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151 results on '"Campos-Domínguez, Minia"'

6. Upadacitinib for the Treatment of Atopic Dermatitis in a Spanish Cohort—Real Life: Fifty-Two–Week Follow-up Results

Author

Pereyra-Rodriguez, Jose-Juan, primary, Herranz, Pedro, additional, Figuras-Nart, Ignasi, additional, Perez, Bibiana, additional, Elosua, Marta, additional, Munera-Campos, Monica, additional, Melgosa-Ramos, Javier, additional, Zaragoza Ninet, Violeta, additional, Silvestre, Juan Francisco, additional, Campos-Domínguez, Minia, additional, Guilabert, Antonio, additional, Miquel, Javier, additional, Alcantara-Luna, Sara, additional, de la Cueva, Pablo, additional, Serra-Baldrich, Esther, additional, and Armario-Hita, Jose Carlos, additional

Published
2022
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9. Inter‐ and intra‐observer variability in the selection of therapy for infantile hemangiomas among pediatric dermatologists in Spain

Author

Colmenero, María, primary, del Boz, Javier, additional, Bernabeu Wittel, José, additional, Roé, Esther, additional, Feito‐Rodríguez, Marta, additional, Vicente‐Villa, María Asunción, additional, Martín‐Santiago, Ana, additional, Palencia Pérez, Sara Isabel, additional, Azon, Antoni, additional, Valdivielso‐Ramos, Marta, additional, Torrelo, Antonio, additional, Sánchez Moya, Ana Isabel, additional, Campos‐Domínguez, Minia, additional, Garnacho‐Saucedo, Gloria, additional, Azaña Defez, José Manuel, additional, Vera Casaño, Ángel, additional, Tercedor‐Sánchez, Jesús, additional, Alcalá, Rebeca, additional, González‐Enseyat, María Antonia, additional, Giacaman, Aniza, additional, Hernández‐Martin, Ángela, additional, Monserrat García, María Teresa, additional, Bauzá, Ana, additional, Domínguez‐Cruz, Javier, additional, García‐Doval, Ignacio, additional, and Grau‐Pérez, Mercè, additional

Published
2022
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15. Baseline Description of the Spanish Academy of Dermatology Infantile Haemangioma Nationwide Prospective Cohort. Comparison of Patients Treated with Propranolol in Routine Clinical Practice with Previous Pivotal Clinical Trial Data Descripción basal de la cohorte nacional prospectiva de hemangiomas infantiles de la Academia Española de Dermatología y Venereología. Comparación de los pacientes tratados con propranolol en la práctica clínica rutinaria y los datos del ensayo clínico pivotal previo

Author

Cuenca-Barrales, Carlos, Baselga Torres, Eulàlia, del Boz-González, Javier, Vicente-Villa, Asunción, Palencia-Pérez, Sara Isabel, Campos-Domínguez, Minia, Valdivieso-Ramos, M., Martín-Santiago, Ana, Monserrat-García, Maria Teresa, Azon, Antoni, Feito-Rodríguez, Marta, Domínguez-Cruz, Javier Jesús, Roé Crespo, Esther, Salas-Márquez, Cristina, Giacaman, Aniza, Lorente-Lavirgen, Ana Isabel, Quintana-Castanedo, Lucía, de Vega-Martínez, Marina, García-Doval, Ignacio, and Bernabéu-Wittel, José

Subjects
Haemangioma, Capillary, Cross-sectional studies, Timolol, Prospective studies, Propranolol
Abstract

Altres ajuts: Fundación Piel Sana AEDV. Background: There are several therapeutic options for infantile haemangiomas (IH). Propranolol is used according to a pivotal trial. We aimed to describe the characteristics of IH in clinical practice, including the therapies used, and to compare the characteristics of patients treated with propranolol with those of the trial to assess its external validity. Methods: Consecutive patients attending 12 Spanish hospitals from June 2016 to October 2019 were included (n = 601). Results: The mean age was 3.9 (SD:1.9) months, with a 2:1 female-to-male ratio. Most IHs were localized (82%, 495), superficial (64%, 383) and located in the face (25%, 157) and trunk (31%, 188). Median size was 17 (IR: 10-30) x 12 (IR: 7-20) mm. Complications were found in 16 (3%) patients. Treatment was initiated for 52% (311). Most patients received timolol (76%, 237); propranolol was reserved for complications or high-risk IHs. Aesthetic impairment was the main reason for starting therapy (64%, 199). Several characteristics of the patients and IHs treated with propranolol are similar to those of the pivotal clinical trial, but 1/3 of IHs did not reach the minimum diameter to meet the inclusion criteria, and important prognostic information was not reported. Conclusions: As most patients receive treatment for aesthetic impairment, there is a need to better understand the aesthetic results of therapies and to increase evidence on the use of timolol, which is currently the most common therapy. Propranolol is being used in a population generally similar to that of the trial; however, this statement cannot be definitely confirmed.

Published
2021

16. Dermatofibrosarcoma protuberans pigmentado: Descripción de un caso pediátrico

Author

Nieto-Benito, LM, Berenguer-Fröhner, Beatriz, Parra-Blanco, Verónica, and Campos-Domínguez, Minia

Subjects
Mohs surgery, Cirugía de Mohs, Dermatofibrosarcoma, Tumores cutáneos, Artificial, Sarcoma, Skin Neoplasm, Piel, Skin
Abstract

Resumen: Introducción: El tumor de Bednar es un sarcoma de bajo grado, infrecuente, considerado como la variante pigmen tada del dermatofibrosarcoma protuberans (DFSP). Objetivo: describir las características clínicas, histopatológicas, el tratamiento y la evolución de un caso pediátrico de esta infrecuente neoplasia. Caso Clínico: escolar de 9 años que consultó por una pápula indurada asintomática, de dos años de evolución en el dorso del cuarto dedo del pie izquierdo. La biopsia incisional de la lesión fue com patibles con un DFSP pigmentado. El estudio inmunohistoquímico mostró positividad intensa para CD34 en toda la lesión, con factor XIIIa negativo. Se complementó el estudio de la pieza histológica con citogenética molecular FISH para el gen PDGFB (22q13.1) el cual reflejó un patrón anómalo en las células tumorales, no así en los melanocitos ni en la piel peritumoral. Se realizó cirugía micrográfica de Mohs diferida con cobertura mediante sustituto dérmico, sin recidiva ni recurrencia tumoral a los 5 años de seguimiento. Conclusiones: El DFSP pigmentado es un sarcoma de bajo grado, que muy infrecuentemente se presenta en pacientes pediátricos. Las variantes clásica y pigmentada deben ser sospechadas ante una lesión papulonodular única, de crecimiento lento y progresivo, con presencia de células fusiformes con patrón estoriforme en la biopsia y con estudio inmunohistoquímico positi vo para CD34. Es una entidad con buen pronóstico, con escaso riesgo de recurrencia y metástasis, si se logra la realización de una extirpación completa. Abstract: Introduction: Bednar tumor is a rare low-grade sarcoma considered the pigmented variant of dermatofibrosarco ma protuberans (DFSP). Objective: To describe the clinical and histopathological characteristics, treatment and evolution of this rare neoplasm. Clinical Case: A 9-year old female presented with a 2-year history of an indurated, asymptomatic papule on the back of her fourth left toe. The incisio nal biopsy was compatible with pigmented DFSP. The immunohistochemical study showed intense positivity for CD34 throughout the lesion, with negative factor XIIIa. We complemented the study with molecular cytogenetics (FISH) for PDGFB gene (22q13.1) which showed an abnormal pattern in tumor cells, but not in the melanocytes or the peritumoral skin. Delayed Mohs surgery and skin substitute dressing were performed without neoplastic recurrence at 5 years of follow up. Conclu sion: Pigmented DFSP is a low-grade sarcoma that is very rare in pediatric patients. The classical and pigmented variants should be suspected in the presence of a single papulonodular lesion of slow and progressive growth, with presence of spindle cells with storiform pattern in the biopsy and positive immunohistochemical study for CD34. It is an entity with good prognosis, with little risk of recurren ce and metastasis, if complete excision is achieved.

Published
2019

23. Congenital tufted angioma: A multicenter retrospective study of 30 cases

Author

Feito-Rodríguez, Marta, primary, Sánchez-Orta, Alba, additional, De Lucas, Raúl, additional, López-Gutiérrez, Juan Carlos, additional, Ruiz-Bravo, Elena, additional, Baselga, Eulalia, additional, Victoria, Ana M., additional, Hernández-Martín, Angela, additional, Campos-Domínguez, Minia, additional, Berenguer Fröhner, Beatriz, additional, Garnacho-Saucedo, Gloria, additional, Vera Casaño, Angel, additional, Vicente Villa, Asunción, additional, Bernabeu-Wittel, José, additional, Kutzner, Heinz, additional, and Requena, Luis, additional

Published
2018
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24. Dermatitis facticia, estudio retrospectivo de 28 pacientes

Author

Vilas Boas, Pedro, primary, Ruedas-Martínez, Antonio, additional, Campos-Domínguez, Minia, additional, Barchino-Ortiz, Lucia, additional, Avilés-Izquierdo, José Antonio, additional, Ciudad-Blanco, Cristina, additional, and Suárez-Fernández, Ricardo, additional

Published
2018
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27. Omeprazole-induced hypertrichosis in two children

Author

Elosua-González, Marta, primary, Campos-Domínguez, Minia, additional, Bancalari, Daniel, additional, Noguera-Morel, Lucero, additional, Hernández-Martín, Angela, additional, Huerta-Aragonés, Jorge, additional, and Torrelo, Antonio, additional

Published
2018
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30. Microscopía confocal en las enfermedades ampollosas subepidérmicas autoinmunes

Author

Sánchez-Mateos Rubio, Paloma, Suárez Fernández, Ricardo, Millán Salas, Jesús, Campos Domínguez, Minia, Sánchez-Mateos Rubio, Paloma, Suárez Fernández, Ricardo, Millán Salas, Jesús, and Campos Domínguez, Minia

Abstract

Las enfermedades ampollosas subepidérmicas autoinmunes constituyen un complejo grupo de trastornos cutáneos en cuya patogenia se rompe la unión dermoepidérmica. Su alta morbilidad se debe a la afectación de grandes áreas cutáneas por ampollas, erosiones o cicatrices y a la posible afectación de las mucosas oral, conjuntival, laríngea, esofágica y genitourinaria. Además, se ha demostrado su asociación con enfermedades neurológicas degenerativas y neoplasias. Existe un gran solapamiento clínico e histológico entre múltiples enfermedades, ya que varios antígenos de la membrana basal pueden estar implicados. En las dos últimas décadas se han producido grandes avances para intentar descubrir todos los antígenos implicados y la posible correlación clínico-inmunológica entre manifestaciones clínicas y antígenos diana. La inmunofluorescencia directa e indirecta y técnicas serológicas como el ELISA se realizan ya de rutina en centros de referencia. Sin embargo, estas técnicas no siempre llegan al diagnóstico de certeza. El desarrollo de nuevas técnicas inmunológicas más sensibles, específicas y reproducibles contribuirá a que los diagnósticos sean más exactos y por tanto el manejo terapéutico y pronóstico de los enfermos sea mejor. La microscopía confocal es una técnica prometedora en este campo..., Subepidermal autoimmune bullous diseases are a complex group of entities featuring rupture of the dermal-epidermal junction. Its high morbidity is caused by blisters, erosions and scars all over the skin surface. Involvement of mucous membranes (oral, conjunctival, laryngeal, esophagic and genital) is possible. Besides, an association with neurologic and oncologic disease has been stated. There is a great clinical and histological overlap between different diseases, because several antigens can be involved. In the last two decades, new antigens have been discovered, with clinicalimmunological correlation. Direct immunofluorescence, indirect immunofluorescence and serological techniques such as ELISA are already performed in referral centers. However, these techniques do not always lead to a certain diagnosis. Development of new immunological tests, sensitive, specific and reproducible will improve diagnostic accuracy, patient management and prognosis. Confocal microscopy is a promising technique in this field...

Published
2017

31. Microscopía confocal en las enfermedades ampollosas subepidérmicas autoinmunes

Author

Campos Domínguez, Minia, Sánchez-Mateos Rubio, Paloma, Suárez Fernández, Ricardo, and Millán Salas, Jesús

Subjects
Dermatología
Abstract

Las enfermedades ampollosas subepidérmicas autoinmunes constituyen un complejo grupo de trastornos cutáneos en cuya patogenia se rompe la unión dermoepidérmica. Su alta morbilidad se debe a la afectación de grandes áreas cutáneas por ampollas, erosiones o cicatrices y a la posible afectación de las mucosas oral, conjuntival, laríngea, esofágica y genitourinaria. Además, se ha demostrado su asociación con enfermedades neurológicas degenerativas y neoplasias. Existe un gran solapamiento clínico e histológico entre múltiples enfermedades, ya que varios antígenos de la membrana basal pueden estar implicados. En las dos últimas décadas se han producido grandes avances para intentar descubrir todos los antígenos implicados y la posible correlación clínico-inmunológica entre manifestaciones clínicas y antígenos diana. La inmunofluorescencia directa e indirecta y técnicas serológicas como el ELISA se realizan ya de rutina en centros de referencia. Sin embargo, estas técnicas no siempre llegan al diagnóstico de certeza. El desarrollo de nuevas técnicas inmunológicas más sensibles, específicas y reproducibles contribuirá a que los diagnósticos sean más exactos y por tanto el manejo terapéutico y pronóstico de los enfermos sea mejor. La microscopía confocal es una técnica prometedora en este campo...

Published
2016

33. Kaposiform Hemangioendothelioma Presenting as Hydrops Fetalis

Author

Sobrino-Fernández, Elena, primary, Campos-Domínguez, Minia, additional, Gregorio-Hernández, Rebeca, additional, Huerta-Aragonés, Jorge, additional, Beléndez-Bieler, Cristina, additional, Lancharro-Zapata, Ángel, additional, Franco-Fernández, María Luisa, additional, Bernardo-Atienza, Belén, additional, and Sánchez-Luna, Manuel, additional

Published
2017
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40. La presencia del infoentretenimiento en los canales generalistas de la TDT española

Author

Berrocal Gonzalo, Salomé, Redondo García, Marta, Martín Jiménez, Virginia, Campos Domínguez, Minia, Berrocal Gonzalo, Salomé, Redondo García, Marta, Martín Jiménez, Virginia, and Campos Domínguez, Minia

Abstract

Introduction. This article is part of the strand of empirical studies on infotainment and presents a characterisation of the infotainment content broadcast by the Spanish mainstream DTT channels. Method. The study is based on the analysis of the infotainment content included in the programming of the six most important mainstream DTT channels in Spain, and the content analysis of the prime time infotainment content. Results. Infotainment occupies a privileged position in the mainstream television channels but there are significant differences across networks. The main distinctive features that characterise infotainment are humour, drama and the use of technical resources to increase the sensationalism of images. Discussion. Infotainment is consolidated as a relevant macro-genre whose presence ranges from 34.91% (in La Sexta) to 8.12% (in La 2), being the magazine and debate shows the dominant formats. Surprisingly, the presence of infotainment in TVE 1 (18.10%) is higher than in the networks Antena 3 and Cuatro., Introducción. El artículo se incluye dentro de las investigaciones empíricas sobre infoentretenimiento y realiza una caracterización de los estilemas del infoentretenimiento televisivo comprobando su presencia dentro de la programación de los canales generalistas de la TDT española. Metodología. Se analizan las parrillas de los seis canales generalistas contabilizando el tiempo dedicado al infoentretenimiento; posteriormente se realiza un análisis de contenido de los espacios en prime time. Resultados. Se observa cómo el infoentretenimiento ocupa una posición privilegiada dentro de la programación aunque con diferencias significativas entre cadenas. Como estilemas dominantes destacan el humorismo, la dramatización y los recursos técnicos para espectacularizar la imagen. Discusión. El infoentretenimiento se consolida como un macrogénero relevante con porcentajes que van del 34,91% (La Sexta) al 8,12% (La 2), siendo el magazine y el debate los formatos dominantes. Sorprendentemente La 1 de

Published
2014

42. Miliaria cristalina

Author

Horcajada-Reales, Celia, primary, Conde-Montero, Elena, additional, Campos-Domínguez, Minia, additional, and Suárez-Fernández, Ricardo, additional

Published
2014
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44. Necrosis cutánea por vancomicina

Author

Borregón Nofuentes, Paloma, primary, Campos Domínguez, Minia, additional, Parra Blanco, Verónica, additional, Pulido Pérez, Ana, additional, Horcajada Reales, Celia, additional, and Suárez Fernández, Ricardo, additional

Published
2012
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47. Pili Annulati

Author

Barchino Ortiz, Lucía, primary, Campos Domínguez, Minia, additional, and Lázaro Ochaita, Pablo, additional

Published
2010
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50. Langerhans cell histiocytosis mimicking lichen nitidus with bone involvement.

Author

Lozano Masdemont, Belén, Gómez‐Recuero Muñoz, Laura, Villanueva Álvarez‐Santullano, Ana, Parra Blanco, Verónica, and Campos Domínguez, Minia

Subjects
SKIN disease diagnosis, BONE diseases, HUMAN skin color, BIOPSY, DISEASE risk factors
Abstract

We report the case of a 6-month-old Hispanic boy with a 4-month history of widespread pruritic hypopigmented papules mimicking lichen nitidus. The final diagnosis was multisystem non-risk-organ Langerhans cell histiocytosis ( LCH), with cutaneous and multiple bone involvement. With this patient and others previously reported in the literature, we suggest an early biopsy of the hypopigmented rash in children. [ABSTRACT FROM AUTHOR]

Published
2017
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