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1. Comparative study of colorimetric in situ hybridization and quantitative real-time polymerase chain reaction for diagnosis of infection by 'Leishmania infantum' in dogs in formalin-fixed and paraffin-embedded skin

Author

Silva, Ricardo Goncalves, Kiupel, Matti, Langohr, Ingeborg Maria, Wise, Annabel, Pereira, Sandro Antonio, Goncalves, Natalia Pedra, da Conceicao, Greice Maria Silva, Ferreira, Luiz Claudio, de Campos, Monique Paiva, de Freitas Campos Miranda, Luciana, Figueiredo, Fabiano Borges, de Vasconcellos Carvalhaes de Oliveira, Raquel, Keidel, Lucas, and Menezes, Rodrigo Caldas

Published
2024

8. A case of canine visceral leishmaniasis of unknown origin in Curitiba (state of Paraná, Brazil) treated successfully with miltefosine

Author

Gonçalves, Gustavo, primary, Campos, Monique Paiva, additional, Tirado, Thais Cristina, additional, Negrão, Dayane Domingos, additional, Silva, Gabriela Mayoral Pedroso da, additional, Poleto, Ana Paula Coninck Mafra, additional, Hartin, Tatianna Paula, additional, Silva, Juliana Batista Andrade, additional, Castilhos, Marilia de Melo Santos de, additional, and Figueiredo, Fabiano Borges, additional

Published
2023
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9. Serosurvey of anti-Leishmania (Leishmania) infantum antibodies in hunting dogs and hunters in Brazil

Author

Kmetiuk, Louise Bach, primary, de Campos, Monique Paiva, additional, Bach, Renato van Wilpe, additional, Brandão, Ana Pérola Drulla, additional, de Barros-Filho, Ivan Roque, additional, Lipinski, Leandro Cavalcante, additional, Fávero, Giovani Marino, additional, dos Santos, Andrea Pires, additional, Fiqueiredo, Fabiano Borges, additional, and Biondo, Alexander Welker, additional

Published
2021
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11. Frequency of co-seropositivities for certain pathogens and their relationship with clinical and histopathological changes and parasite load in dogs infected with Leishmania infantum

Author

Oliveira, Valéria da Costa, primary, Junior, Artur Augusto Velho Mendes, additional, Ferreira, Luiz Claudio, additional, Calvet, Tatiana Machado Quinates, additional, dos Santos, Shanna Araujo, additional, Figueiredo, Fabiano Borges, additional, Campos, Monique Paiva, additional, Rodrigues, Francisco das Chagas de Carvalho, additional, de Oliveira, Raquel de Vasconcellos Carvalhaes, additional, de Lemos, Elba Regina Sampaio, additional, Rozental, Tatiana, additional, da Silva, Raphael Gomes, additional, Amendoeira, Maria Regina Reis, additional, Teles-de-Freitas, Rayane, additional, Bruno, Rafaela Vieira, additional, Morgado, Fernanda Nazaré, additional, Miranda, Luciana de Freitas Campos, additional, and Menezes, Rodrigo Caldas, additional

Published
2021
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13. First description of parasite load and clinicopathological and anatomopathological changes in a dog naturally coinfected with Dioctophyme renale and Leishmania infantum in Brazil

Author

Oliveira, Valéria da Costa, primary, Mendes Junior, Artur Augusto Velho, additional, Cavalcanti, Maíra Cruz de Holanda, additional, Madeira, Maria de Fátima, additional, Ferreira, Luiz Cláudio, additional, Figueiredo, Fabiano Borges, additional, Campos, Monique Paiva de, additional, Nadal, Niara Vanat, additional, Almosny, Nádia Regina Pereira, additional, and Menezes, Rodrigo Caldas, additional

Published
2019
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14. Correction: Frequency of co-seropositivities for certain pathogens and their relationship with clinical and histopathological changes and parasite load in dogs infected with Leishmania infantum.

Author

Oliveira, Vale´ria da Costa, Junior, Artur Augusto Velho Mendes, Ferreira, Luiz Claudio, Calvet, Tatiana Machado Quinates, Santos, Shanna Araujo dos, Figueiredo, Fabiano Borges, Campos, Monique Paiva, Rodrigues, Francisco das Chagas de Carvalho, Oliveira, Raquel de Vasconcellos Carvalhaes de, Lemos, Elba Regina Sampaio de, Rozental, Tatiana, Silva, Raphael Gomes da, Amendoeira, Maria Regina Reis, Teles-de-Freitas, Rayane, Bruno, Rafaela Vieira, Morgado, Fernanda Nazare, Miranda, Luciana de Freitas Campos, and Menezes, Rodrigo Caldas

Subjects
LEISHMANIA infantum, DOG parasites, HISTOPATHOLOGY, MAMMARY glands, SPELLING errors, PATHOGENIC microorganisms
Abstract

This document is a correction notice for an article titled "Frequency of co-seropositivities for certain pathogens and their relationship with clinical and histopathological changes and parasite load in dogs infected with Leishmania infantum." The correction addresses an error in the spelling of the fourth author's name and an error in Table 2, where the histological change in the sample "Mammary gland" should be "Non-granulomatous mastitis" instead of "Non-granulomatous endocarditis." The correct citation for the article is provided, along with the correct information for Table 2. The document also includes copyright information and a reference to the original article. [Extracted from the article]

Published
2023
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15. Corrigendum: Leishmania infantum Virulence Factor A2 Protein: Linear B-Cell Epitope Mapping and Identification of Three Main Linear B-Cell Epitopes in Vaccinated and Naturally Infected Dogs

Author

Campos, Monique Paiva, primary, Figueiredo, Fabiano Borges, additional, Morgado, Fernanda Nazaré, additional, Renzetti, Alinne Rangel dos Santos, additional, de Souza, Sara Maria Marques, additional, Pereira, Sandro Antônio, additional, Rodrigues-Da-Silva, Rodrigo Nunes, additional, Lima-Junior, Josué Da Costa, additional, and De Luca, Paula Mello, additional

Published
2018
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16. Can vaccines against canine visceral leishmaniasis interfere with the serological diagnostics recommended by the Brazilian Ministry of Health?

Author

Campos, Monique Paiva de, Luca, Paula Mello De, Renzetti, Alinne Rangel dos Santos, Souza, Sara Maria Marques de, Mendes Júnior, Artur Augusto Velho, Barros, Renata Simões, and Figueiredo, Fabiano Borges

Subjects
leishmaniose visceral canina, diagnosis, soroconversão, vaccine, vacina, seroconversion, canine visceral leishmaniasis, diagnóstico
Abstract

The objective of the current research was to assess seroconversion in dogs immunized with Leishmune® and Leish Tec® vaccines using rapid chromatographic immunoassay DPP® (Dual Path Platform) (DPP CVL) and enzyme immunoassay (EIE) up to one year after the vaccination protocol. The study sample comprised 28 dogs divided into two groups, each group immunized with an anti-CVL vaccine and clinically monitored for one year through clinical evaluation and laboratory tests. 22 (78.5%) dog were monitored. During the evaluation time (T1-30 days, T2-6 months, and T3-1 year after vaccination) the results for all dogs were negative for CVL, except for one animal vaccinated with Leish tec® that seroconverted in the DPP CVL test at T2. Subsequent examinations of this dog were negative. Our results showed that in a non-endemic area, even at different evaluation times, dogs vaccinated against CVL with Leishmune® or Leish tec® did not seroconvert in the serological protocol used by the Brazilian Ministry of Health (DPP/EIE). RESUMO: O objetivo deste trabalho foi avaliar a soroconversão em cães imunizados com as vacinas Leishmune® e Leish tec®, através do teste imunocromatográfico rápido DPP® (Dual Path Platform) (DPP LVC) e do ensaio imunoenzimático (EIE) durante um ano após o protocolo vacinal. Trata-se de um estudo onde 28 cães divididos em dois grupos foram imunizados cada um com uma vacina anti - LVC e acompanhados durante um ano através de avaliação clínica e exames laboratoriais. Foi possível acompanhar 22 (78.5%) cães. Nos exames dos tempos 1, 2 e 3 (respectivamente 30 dias, 6 messes e 1 ano após a vacinação) os resultados de todos os cães também foram negativos para LVC, exceto de um cão que recebeu a vacina Leish tec® e soroconverteu no DPP LVC no T2, após 6 meses a vacina. Os exames posteriores deste cão foram negativos. Os resultados do presente estudo demostraram que, em área não endêmica e mesmo em diferentes tempos de avaliação, cães vacinados contra LVC, independente da vacina utilizada, não foram capazes de soroconverter no protocolo utilizado pelo Ministério da Saúde brasileiro (DPP/EIE).

Published
2017

17. Leishmania infantum Virulence Factor A2 Protein: Linear B-Cell Epitope Mapping and Identification of Three Main Linear B-Cell Epitopes in Vaccinated and Naturally Infected Dogs

Author

Campos, Monique Paiva, primary, Figueiredo, Fabiano Borges, additional, Morgado, Fernanda Nazaré, additional, Renzetti, Alinne Rangel dos Santos, additional, de Souza, Sara Maria Marques, additional, Pereira, Sandro Antônio, additional, Rodrigues-Da-Silva, Rodrigo Nunes, additional, Lima-Junior, Josué Da Costa, additional, and De Luca, Paula Mello, additional

Published
2018
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18. Impact of 4% Deltamethrin-Impregnated Dog Collars on the Prevalence and Incidence of Canine Visceral Leishmaniasis

Author

Kazimoto, Thaís Aparecida, primary, Amora, Sthenia Santos Albano, additional, Figueiredo, Fabiano Borges, additional, Magalhães, Jamille Maia e, additional, Freitas, Yannara Barbosa Nogueira, additional, Sousa, Maressa Laíse Reginaldo, additional, Melo, Anne Emanuelle Câmara da Silva, additional, Campos, Monique Paiva, additional, Alves, Nilza Dutra, additional, and Werneck, Guilherme Loureiro, additional

Published
2018
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19. Occurrence of Leishmania infantum in the central nervous system of naturally infected dogs: Parasite load, viability, co-infections and histological alterations

Author

Oliveira, Valéria da Costa, primary, Boechat, Viviane Cardoso, additional, Mendes Junior, Artur Augusto Velho, additional, Madeira, Maria de Fátima, additional, Ferreira, Luiz Claudio, additional, Figueiredo, Fabiano Borges, additional, Campos, Monique Paiva, additional, de Carvalho Rodrigues, Francisco das Chagas, additional, Carvalhaes de Oliveira, Raquel de Vasconcellos, additional, Amendoeira, Maria Regina Reis, additional, and Menezes, Rodrigo Caldas, additional

Published
2017
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21. Cytokine and iNOS profiles in lymph nodes of dogs naturally infected with Leishmania infantum and their association with the parasitic DNA load and clinical and histopathological features

Author

de Vasconcelos, Tassia Cristina Bello, primary, Doyen, Noelle, additional, Cavaillon, Jean-Marc, additional, Bruno, Sávio Freire, additional, de Campos, Monique Paiva, additional, de Miranda, Luisa Helena Monteiro, additional, Madeira, Maria de Fátima, additional, Belo, Vinícius Silva, additional, and Figueiredo, Fabiano Borges, additional

Published
2016
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22. Can vaccines against canine visceral leishmaniasis interfere with the serological diagnostics recommended by the Brazilian Ministry of Health?

Author

de Campos, Monique Paiva, De Luca, Paula Mello, dos Santos Renzetti, Alinne Rangel, de Souza, Sara Maria Marques, Velho Mendes Júnior, Artur Augusto, Simões Barros, Renata, and Borges Figueiredo, Fabiano

Subjects
*VISCERAL leishmaniasis, *SEROCONVERSION, *DOG vaccination, *ENZYME-linked immunosorbent assay, *VACCINATION
Abstract

The objective of the current research was to assess seroconversion in dogs immunized with Leishmune® and Leish Tec® vaccines using rapid chromatographic immunoassay DPP® (Dual Path Platform) (DPP CVL) and enzyme immunoassay (EIE) up to one year after the vaccination protocol. The study sample comprised 28 dogs divided into two groups, each group immunized with an anti-CVL vaccine and clinically monitored for one year through clinical evaluation and laboratory tests. 22 (78.5%) dog were monitored. During the evaluation time (T1-30 days, T2-6 months, and T3-1 year after vaccination) the results for all dogs were negative for CVL, except for one animal vaccinated with Leish tec® that seroconverted in the DPP CVL test at T2. Subsequent examinations of this dog were negative. Our results showed that in a non-endemic area, even at different evaluation times, dogs vaccinated against CVL with Leishmune® or Leish tec® did not seroconvert in the serological protocol used by the Brazilian Ministry of Health (DPP/EIE). [ABSTRACT FROM AUTHOR]

Published
2017
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24. Impact of 4% Deltamethrin-Impregnated Dog Collars on the Prevalence and Incidence of Canine Visceral Leishmaniasis.

Author

Kazimoto TA, Amora SSA, Figueiredo FB, Magalhães JME, Freitas YBN, Sousa MLR, Melo AECDS, Campos MP, Alves ND, and Werneck GL

Subjects
Animals, Brazil epidemiology, Dog Diseases epidemiology, Dogs, Female, Insecticides administration & dosage, Leishmania infantum, Leishmaniasis, Visceral epidemiology, Leishmaniasis, Visceral prevention & control, Male, Nitriles administration & dosage, Pyrethrins administration & dosage, Seroepidemiologic Studies, Dog Diseases prevention & control, Insecticides pharmacology, Leishmaniasis, Visceral veterinary, Nitriles pharmacology, Pyrethrins pharmacology
Abstract

In Brazil, visceral leishmaniasis is caused by the protozoan Leishmania infantum, primarily transmitted by Lutzomyia longipalpis and with the dog as its main urban reservoir. This study aims to evaluate the effectiveness of 4% deltamethrin-impregnated dog collars (DMC) DIC, Scalibor ® 65 cm model and MSD manufacturer, on the prevalence and incidence of canine visceral leishmaniasis (CVL) and on the rate of infection of sandflies by L. infantum. The research was conducted in two areas of the municipality Mossoró, State of Rio Grande do Norte in Northeast of Brazil. Two semiannual serosurveys, followed by culling seropositive dogs, and searches for phlebotominae were performed in the control area (CA), whereas in the collar intervention area (IA), aside from those procedures, DMC were fitted to dogs every 6 months. CVL was diagnosed by the Dual Path Platform rapid test (TR-DPP ® ) and the Immunoenzymatic assay (EIE). The sandflies were collected monthly, identified, and the females were submitted to Quantitative Real-Time Polymerase Chain Reaction for detection of L. infantum DNA. The use of collars was associated with a 53-59% reduction in the incidence of CVL. The most abundant phlebotomine species were L. longipalpis (81.8%). Positive pools of L. longipalpis were obtained in the IA only in the first survey, whereas the presence of the DNA of the parasite in the vector was observed in the CA in both surveys. We conclude that the continuous use of these collars may have the potential to reduce both the incidence of CVL and the rate of infected phlebotomine sandflies.

Published
2018
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25. First autochthonous case of canine visceral leishmaniasis in Volta Redonda, Rio de Janeiro, Brazil.

Author

de Campos MP, da Silva DA, Madeira Mde F, Velho AA Jr, and Figueiredo FB

Subjects
Animals, Brazil, Dogs, Female, Dog Diseases parasitology, Leishmaniasis, Visceral veterinary
Abstract

In Brazil, American visceral leishmaniasis (AVL) is caused by Leishmania (Leishmania) chagasi and its main vector is Lutzomyia longipalpis. Cases of canine visceral leishmaniasis (CVL) in non-endemic areas have been reported over the last few years throughout the country. The objective of this research note is to describe an autochthonous case of CVL that occurred in the municipality of Volta Redonda, state of Rio de Janeiro, an area where the disease is not endemic, alerting veterinarians and the scientific community to the expansion of this important zoonosis and advising veterinary practitioners on how to deal with a suspicion of CVL. Canine visceral leishmaniasis can be misdiagnosed within a broad spectrum of canine diseases based on clinical and laboratory findings. Therefore, knowledge of its clinical manifestations, specific and sensitive laboratory diagnostic tests and parasitological procedures are of the utmost importance for rapid confirmation and notification of a case, thus contributing directly to the control of a focus.

Published
2013
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