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1,227 results on '"Campo G."'

1. Comparison of “IN-REC-SUR-E” and LISA in preterm neonates with respiratory distress syndrome: a randomized controlled trial (IN-REC-LISA trial)

Author

Vento, Giovanni, Paladini, Angela, Aurilia, C., Ozdemir, S. Alkan, Carnielli, V. P., Cools, F., Costa, S., Cota, F., Dani, C., Davis, P. G., Fattore, S., Fè, C., Finer, N., Fusco, F. P., Gizzi, C., Herting, E., Jian, M., Lio, A., Lista, G., Mosca, F., Nobile, S., Perri, A., Picone, S., Pillow, J. J., Polglase, G., Pasciuto, T., Pastorino, R., Tana, M., Tingay, D., Tirone, C., van Kaam, A. H., Ventura, M. L., Aceti, A., Agosti, M., Alighieri, G., Ancora, G., Angileri, V., Ausanio, G., Aversa, S., Balestri, E., Baraldi, E., Barbini, M. C., Barone, C., Beghini, R., Bellan, C., Berardi, A., Bernardo, I., Betta, P., Binotti, M., Bizzarri, B., Borgarello, G., Borgione, S., Borrelli, A., Bottino, R., Bracaglia, G., Bresesti, I., Burattini, I., Cacace, C., Calzolari, F., Campagnoli, M. F., Capasso, L., Capozza, M., Capretti, M. G., Caravetta, J., Carbonara, C., Cardilli, V., Carta, M., Castoldi, F., Castronovo, A., Cavalleri, E., Cavigioli, F., Cecchi, S., Chierici, V., Cimino, C., Cocca, F., Cocca, C., Cogo, P., Coma, M., Comito, V., Condò, V., Consigli, C., Conti, R., Corradi, M., Corsello, G., Corvaglia, L. T., Costa, A., Coscia, A., Cresi, F., Crispino, F., D’Amico, P., De Cosmo, L., De Maio, C., Del Campo, G., Di Credico, S., Di Fabio, S., Di Nicola, P., Di Paolo, A., Di Valerio, S., Distilo, A., Duca, V., Falcone, A., Falsaperla, R., Fasolato, V. A., Fatuzzo, V., Favini, F., Ferrarello, M. P., Ferrari, S., Nastro, F. Fiori, Forcellini, C. A., Fracchiolla, A., Gabriele, A., Galdo, F., Gallini, F., Gangemi, A., Gargano, G., Gazzolo, D., Gentile, M. P., Ghirardello, S., Giardina, F., Giordano, L., Gitto, E., Giuffrè, M., Grappone, L., Grasso, F., Greco, I., Grison, A., Guglielmino, R., Guidotti, I., Guzzo, I., La Forgia, N., La Placa, S., La Torre, G., Lago, P., Lanciotti, L., Lavizzari, A., Leo, F., Leonardi, V., Lestingi, D., Li, J., Liberatore, P., Lodin, D., Lubrano, R., Lucente, M., Luciani, S., Luvarà, D., Maffei, G., Maggio, A., Maggio, L., Maiolo, K., Malaigia, L., Mangili, G., Manna, A., Maranella, E., Marciano, A., Marcozzi, P., Marletta, M., Marseglia, L., Martinelli, D., Martinelli, S., Massari, S., Massenzi, L., Matina, F., Mattia, L., Mescoli, G., Migliore, I. V., Minghetti, D., Mondello, I., Montano, S., Morandi, G., Mores, N., Morreale, S., Morselli, I., Motta, M., Napolitano, M., Nardo, D., Nicolardi, A., Nider, S., Nigro, G., Nuccio, M., Orfeo, L., Ottaviano, C., Paganin, P., Palamides, S., Palatta, S., Paolillo, P., Pappalardo, M. G., Pasta, E., Patti, L., Paviotti, G., Perniola, R., Perotti, G., Perrone, S., Petrillo, F., Piazza, M. S., Piccirillo, A., Pierro, M., Piga, E., Pingitore, G. A., Pisu, S., Pittini, C., Pontiggia, F., Pontrelli, G., Primavera, A., Proto, A., Quartulli, L., Raimondi, F., Ramenghi, L., Rapsomaniki, M., Ricotti, A., Rigotti, C., Rinaldi, M., Risso, F. M., Roma, E., Romanini, E., Romano, V., Rosati, E., Rosella, V., Rulli, I., Salvo, V., Sanfilippo, C., Sannia, A., Saporito, A., Sauna, A., Scapillati, E., Schettini, F., Scorrano, A., Mantelli, S. Semeria, Sepporta, V., Sindico, P., Solinas, A., Sorrentino, E., Spaggiari, E., Staffler, A., Stella, M., Termini, D., Terrin, G., Testa, A., Tina, G., Tirantello, M., Tomasini, B., Tormena, F., Travan, L., Trevisanuto, D., Tuling, G., Tulino, V., Valenzano, L., Vedovato, S., Vendramin, S., Villani, P. E., Viola, S., Viola, V., Vitaliti, G., Vitaliti, M., Wanker, P., Yang, Y., Zanetta, S., and Zannin, E.

Published
2024
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3. Pulmonary Valve Stenosis: From Diagnosis to Current Management Techniques and Future Prospects

Author

Marchini F, Meossi S, Passarini G, Campo G, and Pavasini R

Subjects
pulmonary valve stenosis, percutaneous treatment, valvotomy, valvuloplasty, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Federico Marchini, Sofia Meossi, Giulia Passarini, Gianluca Campo, Rita Pavasini Cardiology Unit, Azienda Ospedaliero Universitaria di Ferrara, Ferrara, ItalyCorrespondence: Rita Pavasini, Cardiology Unit, Azienda Ospedaliero Universitaria di Ferrara, Via Aldo Moro 8, Ferrara, FE, 44124, Italy, Tel +39 0532237227, Email pvsrti@unife.itAbstract: Pulmonary stenosis (PS) is mainly a congenital defect that accounts for 7– 12% of congenital heart diseases (CHD). It can be isolated or, more frequently, associated with other congenital defects (25– 30%) involving anomalies of the pulmonary vascular tree. For the diagnosis of PS an integrated approach with echocardiography, cardiac computed tomography and cardiac magnetic resonance (CMR) is of paramount importance for the planning of the interventional treatment. In recent years, transcatheter approaches for the treatment of PS have increased however, meaning surgery is a possible option for complicated cases with anatomy not suitable for percutaneous treatment. The present review aims to summarize current knowledge regarding diagnosis and treatment of PS.Keywords: pulmonary valve stenosis, percutaneous treatment, valvotomy, valvuloplasty

Published
2023

4. Prevalence and predictive role of hypertriglyceridemia in statin-treated patients at very high risk: Insights from the START study

Author

Steering Committee, De Luca (Chairman), L., Gulizia (co-chairman), M.M., Temporelli, P.L., Riccio, C., Colivicchi, F., Amico, A.F., Formigli, D., Geraci, G., Di Lenarda, A., Executive Committee, De Luca, L., Maggioni, A.P., Lucci, D., Coordinating Center, Lorimer, A., Orsini, G., Gonzini, L., Fabbri, G., Priami, P., Maras, P., Ramani, F., Falcone, C., Passarelli, I., Mauri, S., Calabrò, P., Bianchi, R., Di Palma, G., Mascia, F., Vetrano, A., Fusco, A., Proia, E., Aiello, A., Tomai, F., Licitra, R., Petrolini, A., Bosco, B., Magliari, F., Callerame, M., Mazzella, T., Lettica, G.V., Coco, G., Incao, F., Marinacci, L., D'Addario, S., Tartaglione, S.N., Ubaldi, S., Sanchez, F.A., Costa, P., Manca, G., Failla, M., Scherillo, M., Procaccini, V., Senni, M., Luminita, E.M., Bonomo, P., Mossa, C., Corda, S., Colavita, A.R., Trevisonno, G., Vizzari, G., Cosentino, N., Formaro, C., Paolillo, C., Nalin, I.L., De Rosa, F.M., Fontana, F., Fuscaldo, G.F., Passamonti, E., Bertella, E., Calvaruso, E.V., Varani, E., Tani, F., Cicchitelli, G., Gabrielli, D., Paoloni, P., Marziali, A., Campo, G., Tebaldi, M., Biscaglia, S., Biase, M Di, Brunetti, N.D., Gallotta, A.M., Mattei, L., Marini, R., Balsemin, F., Urbano, M.D., Naio, R., Vicinelli, P., Arena, G., Mazzini, M., Gigli, N., Miserrafiti, B., Monopoli, A., Mortara, A., Delfino, P., Chioffi, M.M., Marino, P., Gravellone, M., Barbieri, L., Ledda, A., Carmina, M.G., Raisaro, A.E., Di Giacomo, C., Somaschini, A., Fasano, M.L., Sannazzaro, M., Arcieri, R., Pantaleoni, M., Leuzzi, C., Gorlato, G., Greco, G., Chiera, A., Ammaturo, T.A., Malanchini, G., Del Corral, M.P., Tedesco, L., Pede, S., Urso, L.G., Piscione, F., Galasso, G., Provasoli, S., Fattore, L., Lucca, G., Cresti, A., Cardillo, A., Fera, M.S., Vennettilli, F., Gaudio, C., Paravati, V., Caldarola, P., Locuratolo, N., Verlato, R., De Conti, F., Turiano, G., Preti, G., Moretti, L., Silenzi, S., Colonna, G., Picciolo, A., Nicosia, A., Cascone, C., Di Sciascio, G., Mangiacapra, F., Russo, A., Mastroianno, S., Esposito, G., Cosmi, F., D'Orazio, S., Costantini, C., Lanari, A., De Rosa, P., Esposito, L., Bilato, C., Valle, C Dalla, Ceresa, M., Colombo, E., Pennisi, V., Casciola, G., Driussi, M., Bisceglia, T., Scalvini, S., Rivadossi, F., Volpe, M., Comito, F., Scorzoni, D., Grimoldi, P., Lagioia, R., Santoro, D., De Cesare, N., Comotti, T., Poli, A., Martina, P., Musolino, M.F., Multari, E.I., Bilardo, G., Scalchi, G., Olivieri, C., Caranci, F., Pavan, D., Ganci, G., Mariani, A., Falchetti, E., Lanzillo, T., Caccavale, A., Bongo, A.S., Rizzi, A., Favilli, R., Maffei, S., Mallardo, M., Fulgione, C., Bordin, F., Bonmassari, R., Battaia, E., Puzzo, A., Vianello, G., D'Arpino, A., Romei, M., Pajes, G., Petronzelli, S., Ghezzi, F., Brigido, S., Pignatelli, L., Brscic, E., Sori, P., Russo, M., Biancolillo, E., Ignone, G., De Giorgio, N.A., Campaniello, C., Ponticelli, P., Margonato, A., Gerosa, S., Cutaia, A., Casalicchio, C., Bartolomucci, F., Larosa, C., Spadafina, T., Putignano, A., De Cristofaro, R., Bernardi, L., Sommariva, L., Celestini, A., Bertucci, C.M., Marchetti, M., Grisolia, E Franceschini, Ammendolea, C., Carini, M., Scipione, P., Politano, M., Rubino, G., Reina, C., Peccerillo, N., Paloscia, L., D'Alleva, A., Petacchi, R., Pignalosa, M., Lucchetti, D., Di Palma, F., La Mastra, R.A., Filippis, M De, Fontanella, B., Zanini, G., Casolo, G., Del Meglio, J., Parato, V.M., Genovesi, E., D'Alimonte, A., Miglioranza, A., Alessandri, N., Moscariello, F., Mauro, C., Sasso, A., Caso, P., Petrillo, C., Napoletano, C., Paparoni, S.R., Bernardo, V., Serdoz, R., Rotunno, R., Oppo, I., Aloisio, A., Aurelio, A., Licciardello, G., Cassaniti, L., Gulizia, M.M., Francese, G.M., Marcassa, C., Villani, R., Zorzoli, F., Mileto, F., Vecchis, M De, Scolozzi, D., Lupi, G., Caruso, D., Rebulla, E., La Fata, B., Anselmi, M., Girardi, P., Borruso, E., Ferrantelli, G., Sassone, B., Bressan, S., Capriolo, M., Pelissero, E., Piancastelli, M., Gobbi, M., Cocco, F., Bruno, M.G., Berti, S., Lo Surdo, G., Tanzi, P., De Rosa, R., Vilei, E., De Iaco, M.R., Grassi, G., Zanella, C., Marullo, L., Alfano, G., Pelaggi, P., Talarico, R., Tuccillo, B., Irace, L., Proietti, F., Di Croce, G., Di Lorenzo, L., Zarrilli, A., Bongini, M., Ranise, A., Aprile, A., Fornengo, C., Capogrosso, V., Tranghese, A., Golia, B., Marziano, A., Roncon, L., Picariello, C., Bagni, E., Leci, E., Gregorio, G., Gatto, F., Piemonte, F., Gervasio, F., Navazio, A., Guerri, E., Belmonte, E., Marino, F., Di Belardino, N., Di Nuzzo, M.R., Epifani, M., Comolatti, G., Conconi, B., Benea, D., Casu, G., Merella, P., Ammirati, M.A., Corrado, V.M., Spagnolo, D., Caico, S.I., Bonizzato, S., Margheri, M., Corrado, L., Antonicelli, R., Ferrigno, C., Merlino, A., Nassiacos, D., Antonelli, A., Marchese, A., Uguccioni, M., Villella, A., Bechi, S., Lo Bianco, F., Bedogni, F., Negro, L., Donato, L., Statile, D., Cassin, M., Fedele, F., Granatelli, A., Calcagno, S., Politi, A., Pani, A., De Luca, Leonardo, Temporelli, Pier Luigi, Gulizia, Michele Massimo, Gonzini, Lucio, Ammaturo, Tiziana Anita, Tedesco, Luigi, Pede, Silvia, Oliva, Fabrizio, Gabrielli, Domenico, Colivicchi, Furio, and Averna, Maurizio R.

Published
2023
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8. Efficacy of “Physiology-Guided PCI” Using Pressure Catheter in Comparison to Conventional Pressure Wires: A Multicenter Analysis

Author

Anastasia, G., Galante, D., Biscaglia, S., Vergallo, Rocco, Di Giusto, F., Migliaro, S., Petrolati, E., Vicere, A., Scancarello, D., Marrone, A., Verardi, F. M., Campaniello, Giorgia, Giuliana, Chiara, Pollio Benvenuto, Ciro, Viccaro, Vincenzo, Todisco, Simona, Burzotta, Francesco, Aurigemma, Cristina, Romagnoli, E., Trani, Carlo, Crea, Filippo, Porto, Italo, Campo, G., Leone, Antonio Maria, Vergallo R., Campaniello G., Giuliana C., Pollio Benvenuto C., Viccaro V., Todisco S., Burzotta F. (ORCID:0000-0002-6569-9401), Aurigemma C., Trani C. (ORCID:0000-0001-9777-013X), Crea F. (ORCID:0000-0001-9404-8846), Porto I. (ORCID:0000-0002-9854-5046), Leone A. M. (ORCID:0000-0002-1276-9883), Anastasia, G., Galante, D., Biscaglia, S., Vergallo, Rocco, Di Giusto, F., Migliaro, S., Petrolati, E., Vicere, A., Scancarello, D., Marrone, A., Verardi, F. M., Campaniello, Giorgia, Giuliana, Chiara, Pollio Benvenuto, Ciro, Viccaro, Vincenzo, Todisco, Simona, Burzotta, Francesco, Aurigemma, Cristina, Romagnoli, E., Trani, Carlo, Crea, Filippo, Porto, Italo, Campo, G., Leone, Antonio Maria, Vergallo R., Campaniello G., Giuliana C., Pollio Benvenuto C., Viccaro V., Todisco S., Burzotta F. (ORCID:0000-0002-6569-9401), Aurigemma C., Trani C. (ORCID:0000-0001-9777-013X), Crea F. (ORCID:0000-0001-9404-8846), Porto I. (ORCID:0000-0002-9854-5046), and Leone A. M. (ORCID:0000-0002-1276-9883)

Abstract

N/A

Published
2024

9. Optimization of the Wastewater Treatment Plant: From Energy Saving to Environmental Impact Mitigation

Author

Panepinto, D., Riggio, V., Ruffino, Barbara, Campo, G., Cerutti, A., Borzooei, S., Ravina, M., Bianco, I., Zanetti, Maria Chiara, Pisello, Anna Laura, Editorial Board Member, Hawkes, Dean, Editorial Board Member, Bougdah, Hocine, Editorial Board Member, Rosso, Federica, Editorial Board Member, Abdalla, Hassan, Editorial Board Member, Boemi, Sofia-Natalia, Editorial Board Member, Mohareb, Nabil, Editorial Board Member, Mesbah Elkaffas, Saleh, Editorial Board Member, Bozonnet, Emmanuel, Editorial Board Member, Pignatta, Gloria, Editorial Board Member, Mahgoub, Yasser, Editorial Board Member, De Bonis, Luciano, Editorial Board Member, Kostopoulou, Stella, Editorial Board Member, Pradhan, Biswajeet, Editorial Board Member, Abdul Mannan, Md., Editorial Board Member, Alalouch, Chaham, Editorial Board Member, O. Gawad, Iman, Editorial Board Member, Amer, Mourad, Series Editor, Naddeo, Vincenzo, editor, Balakrishnan, Malini, editor, and Choo, Kwang-Ho, editor

Published
2020
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14. Vessel-oriented cardiovascular events in patients with diabetes undergoing intracoronary physiology-guided revascularization

Author

Rubino, F, primary, Scarsini, R, additional, Sgreva, S, additional, Tebaldi, M, additional, Vescovo, G, additional, Barbierato, M, additional, Vicere', A, additional, Galante, D, additional, Mammone, C, additional, Lunardi, M, additional, Tavella, D, additional, Pesarini, G, additional, Campo, G, additional, Leone, A M, additional, and Ribichini, F L, additional

Published
2023
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15. Patient-level outcomes of patients undergoing resorbable magnesium scaffold (RMS) implantation stratified according to different subgroups: a post-hoc analysis of SHERPA MAGIC study

Author

Pompei, G, primary, Campo, G, additional, Ruggiero, R, additional, Maffeo, D, additional, Sgura, F, additional, Preti, G, additional, Iannaccone, M, additional, Erriquez, A, additional, Biscaglia, S, additional, Sganzerla, P, additional, Capecchi, A, additional, Pignatelli, G, additional, Dall'ara, G, additional, Varbella, F, additional, and Cerrato, E, additional

Published
2023
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18. Prevalence and predictive role of hypertriglyceridemia in statin-treated patients at very high risk: insights from the START Study

Author

De Luca, Leonardo, primary, Temporelli, Pier Luigi, additional, Gulizia, Michele Massimo, additional, Gonzini, Lucio, additional, Ammaturo, Tiziana Anita, additional, Tedesco, Luigi, additional, Pede, Silvia, additional, Oliva, Fabrizio, additional, Gabrielli, Domenico, additional, Colivicchi, Furio, additional, Averna, Maurizio R., additional, De Luca, L., additional, Gulizia, M.M., additional, Temporelli, P.L., additional, Riccio, C., additional, Colivicchi, F., additional, Amico, A.F., additional, Formigli, D., additional, Geraci, G., additional, Di Lenarda, A., additional, Maggioni, A.P., additional, Lucci, D., additional, Lorimer, A., additional, Orsini, G., additional, Gonzini, L., additional, Fabbri, G., additional, Priami, P., additional, Maras, P., additional, Ramani, F., additional, Falcone, C., additional, Passarelli, I., additional, Mauri, S., additional, Calabrò, P., additional, Bianchi, R., additional, Di Palma, G., additional, Mascia, F., additional, Vetrano, A., additional, Fusco, A., additional, Proia, E., additional, Aiello, A., additional, Tomai, F., additional, Licitra, R., additional, Petrolini, A., additional, Bosco, B., additional, Magliari, F., additional, Callerame, M., additional, Mazzella, T., additional, Lettica, G.V., additional, Coco, G., additional, Incao, F., additional, Marinacci, L., additional, D'Addario, S., additional, Tartaglione, S.N., additional, Ubaldi, S., additional, Sanchez, F.A., additional, Costa, P., additional, Manca, G., additional, Failla, M., additional, Scherillo, M., additional, Procaccini, V., additional, Senni, M., additional, Luminita, E.M., additional, Bonomo, P., additional, Mossa, C., additional, Corda, S., additional, Colavita, A.R., additional, Trevisonno, G., additional, Vizzari, G., additional, Cosentino, N., additional, Formaro, C., additional, Paolillo, C., additional, Nalin, I.L., additional, De Rosa, F.M., additional, Fontana, F., additional, Fuscaldo, G.F., additional, Passamonti, E., additional, Bertella, E., additional, Calvaruso, E.V., additional, Varani, E., additional, Tani, F., additional, Cicchitelli, G., additional, Gabrielli, D., additional, Paoloni, P., additional, Marziali, A., additional, Campo, G., additional, Tebaldi, M., additional, Biscaglia, S., additional, Biase, M Di, additional, Brunetti, N.D., additional, Gallotta, A.M., additional, Mattei, L., additional, Marini, R., additional, Balsemin, F., additional, Urbano, M.D., additional, Naio, R., additional, Vicinelli, P., additional, Arena, G., additional, Mazzini, M., additional, Gigli, N., additional, Miserrafiti, B., additional, Monopoli, A., additional, Mortara, A., additional, Delfino, P., additional, Chioffi, M.M., additional, Marino, P., additional, Gravellone, M., additional, Barbieri, L., additional, Ledda, A., additional, Carmina, M.G., additional, Raisaro, A.E., additional, Di Giacomo, C., additional, Somaschini, A., additional, Fasano, M.L., additional, Sannazzaro, M., additional, Arcieri, R., additional, Pantaleoni, M., additional, Leuzzi, C., additional, Gorlato, G., additional, Greco, G., additional, Chiera, A., additional, Ammaturo, T.A., additional, Malanchini, G., additional, Del Corral, M.P., additional, Tedesco, L., additional, Pede, S., additional, Urso, L.G., additional, Piscione, F., additional, Galasso, G., additional, Provasoli, S., additional, Fattore, L., additional, Lucca, G., additional, Cresti, A., additional, Cardillo, A., additional, Fera, M.S., additional, Vennettilli, F., additional, Gaudio, C., additional, Paravati, V., additional, Caldarola, P., additional, Locuratolo, N., additional, Verlato, R., additional, De Conti, F., additional, Turiano, G., additional, Preti, G., additional, Moretti, L., additional, Silenzi, S., additional, Colonna, G., additional, Picciolo, A., additional, Nicosia, A., additional, Cascone, C., additional, Di Sciascio, G., additional, Mangiacapra, F., additional, Russo, A., additional, Mastroianno, S., additional, Esposito, G., additional, Cosmi, F., additional, D'Orazio, S., additional, Costantini, C., additional, Lanari, A., additional, De Rosa, P., additional, Esposito, L., additional, Bilato, C., additional, Valle, C Dalla, additional, Ceresa, M., additional, Colombo, E., additional, Pennisi, V., additional, Casciola, G., additional, Driussi, M., additional, Bisceglia, T., additional, Scalvini, S., additional, Rivadossi, F., additional, Volpe, M., additional, Comito, F., additional, Scorzoni, D., additional, Grimoldi, P., additional, Lagioia, R., additional, Santoro, D., additional, De Cesare, N., additional, Comotti, T., additional, Poli, A., additional, Martina, P., additional, Musolino, M.F., additional, Multari, E.I., additional, Bilardo, G., additional, Scalchi, G., additional, Olivieri, C., additional, Caranci, F., additional, Pavan, D., additional, Ganci, G., additional, Mariani, A., additional, Falchetti, E., additional, Lanzillo, T., additional, Caccavale, A., additional, Bongo, A.S., additional, Rizzi, A., additional, Favilli, R., additional, Maffei, S., additional, Mallardo, M., additional, Fulgione, C., additional, Bordin, F., additional, Bonmassari, R., additional, Battaia, E., additional, Puzzo, A., additional, Vianello, G., additional, D'Arpino, A., additional, Romei, M., additional, Pajes, G., additional, Petronzelli, S., additional, Ghezzi, F., additional, Brigido, S., additional, Pignatelli, L., additional, Brscic, E., additional, Sori, P., additional, Russo, M., additional, Biancolillo, E., additional, Ignone, G., additional, De Giorgio, N.A., additional, Campaniello, C., additional, Ponticelli, P., additional, Margonato, A., additional, Gerosa, S., additional, Cutaia, A., additional, Casalicchio, C., additional, Bartolomucci, F., additional, Larosa, C., additional, Spadafina, T., additional, Putignano, A., additional, De Cristofaro, R., additional, Bernardi, L., additional, Sommariva, L., additional, Celestini, A., additional, Bertucci, C.M., additional, Marchetti, M., additional, Grisolia, E Franceschini, additional, Ammendolea, C., additional, Carini, M., additional, Scipione, P., additional, Politano, M., additional, Rubino, G., additional, Reina, C., additional, Peccerillo, N., additional, Paloscia, L., additional, D'Alleva, A., additional, Petacchi, R., additional, Pignalosa, M., additional, Lucchetti, D., additional, Di Palma, F., additional, La Mastra, R.A., additional, Filippis, M De, additional, Fontanella, B., additional, Zanini, G., additional, Casolo, G., additional, Del Meglio, J., additional, Parato, V.M., additional, Genovesi, E., additional, D'Alimonte, A., additional, Miglioranza, A., additional, Alessandri, N., additional, Moscariello, F., additional, Mauro, C., additional, Sasso, A., additional, Caso, P., additional, Petrillo, C., additional, Napoletano, C., additional, Paparoni, S.R., additional, Bernardo, V., additional, Serdoz, R., additional, Rotunno, R., additional, Oppo, I., additional, Aloisio, A., additional, Aurelio, A., additional, Licciardello, G., additional, Cassaniti, L., additional, Francese, G.M., additional, Marcassa, C., additional, Villani, R., additional, Zorzoli, F., additional, Mileto, F., additional, Vecchis, M De, additional, Scolozzi, D., additional, Lupi, G., additional, Caruso, D., additional, Rebulla, E., additional, La Fata, B., additional, Anselmi, M., additional, Girardi, P., additional, Borruso, E., additional, Ferrantelli, G., additional, Sassone, B., additional, Bressan, S., additional, Capriolo, M., additional, Pelissero, E., additional, Piancastelli, M., additional, Gobbi, M., additional, Cocco, F., additional, Bruno, M.G., additional, Berti, S., additional, Lo Surdo, G., additional, Tanzi, P., additional, De Rosa, R., additional, Vilei, E., additional, De Iaco, M.R., additional, Grassi, G., additional, Zanella, C., additional, Marullo, L., additional, Alfano, G., additional, Pelaggi, P., additional, Talarico, R., additional, Tuccillo, B., additional, Irace, L., additional, Proietti, F., additional, Di Croce, G., additional, Di Lorenzo, L., additional, Zarrilli, A., additional, Bongini, M., additional, Ranise, A., additional, Aprile, A., additional, Fornengo, C., additional, Capogrosso, V., additional, Tranghese, A., additional, Golia, B., additional, Marziano, A., additional, Roncon, L., additional, Picariello, C., additional, Bagni, E., additional, Leci, E., additional, Gregorio, G., additional, Gatto, F., additional, Piemonte, F., additional, Gervasio, F., additional, Navazio, A., additional, Guerri, E., additional, Belmonte, E., additional, Marino, F., additional, Di Belardino, N., additional, Di Nuzzo, M.R., additional, Epifani, M., additional, Comolatti, G., additional, Conconi, B., additional, Benea, D., additional, Casu, G., additional, Merella, P., additional, Ammirati, M.A., additional, Corrado, V.M., additional, Spagnolo, D., additional, Caico, S.I., additional, Bonizzato, S., additional, Margheri, M., additional, Corrado, L., additional, Antonicelli, R., additional, Ferrigno, C., additional, Merlino, A., additional, Nassiacos, D., additional, Antonelli, A., additional, Marchese, A., additional, Uguccioni, M., additional, Villella, A., additional, Bechi, S., additional, Lo Bianco, F., additional, Bedogni, F., additional, Negro, L., additional, Donato, L., additional, Statile, D., additional, Cassin, M., additional, Fedele, F., additional, Granatelli, A., additional, Calcagno, S., additional, Politi, A., additional, and Pani., A., additional

Published
2023
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24. Impact of age at the time of the first ST-elevation myocardial infarction on 10-year outcomes. A sub-analysis from the EXAMINATION EXTEND trial

Author

Arevalos Rivas, V, primary, Spione, F, additional, Gabani, R, additional, Ortega-Paz, L, additional, Gomez-Lara, J, additional, Jimenez-Diaz, V A, additional, Jimenez, M, additional, Jimenez-Quevedo, P, additional, Diletti, R, additional, Pineda, J, additional, Campo, G, additional, Silvestro, A, additional, Maristany, J, additional, Sabate, M, additional, and Brugaletta, S, additional

Published
2022
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25. Implications of the 2021 CKD-EPI cystatin C/creatinine eGFR equation for eligibility for therapy in HFrEF: insights from PARADIGM-HF

Author

Tolomeo, P, primary, Kondo, T, additional, Butt, J H, additional, Desai, A S, additional, Lefkowitz, M P, additional, Rouleau, J L, additional, Solomon, S D, additional, Swedberg, K, additional, Zile, M R, additional, Campo, G, additional, Jhund, P S, additional, Packer, M, additional, and McMurray, J J V, additional

Published
2022
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26. Long-term effects of coronavirus disease 2019 on the cardiovascular system: the CV COVID-19 registry

Author

Arevalos Rivas, V, primary, Ortega-Paz, L, additional, Fernandez-Rodriguez, D, additional, Jimenez-Diaz, V A, additional, Baneras Rius, J, additional, Campo, G, additional, Diaz, J F, additional, Scardino, C, additional, Rodriguez-Santamarta, M, additional, Gonzalo, N, additional, Perginotti, A, additional, Alfonso, F, additional, Amat-Santos, I, additional, Sabate, M, additional, and Brugaletta, S, additional

Published
2022
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27. The hidden interplay between sex and COVID-19 mortality: the role of cardiovascular calcification

Author

Cereda, A, Toselli, M, Palmisano, A, Vignale, D, Leone, R, Nicoletti, V, Gnasso, C, Mangieri, A, Khokhar, A, Campo, G, Scoccia, A, Bertini, M, Loffi, M, Sergio, P, Andreini, D, Pontone, G, Iannopollo, G, Nannini, T, Ippolito, D, Bellani, G, Patelli, G, Besana, F, Vignali, L, Sverzellati, N, Iannaccone, M, Vaudano, P, Sangiorgi, G, Turchio, P, Monello, A, Tumminello, G, Maggioni, A, Rapezzi, C, Colombo, A, Giannini, F, Esposito, A, Cereda A., Toselli M., Palmisano A., Vignale D., Leone R., Nicoletti V., Gnasso C., Mangieri A., Khokhar A., Campo G., Scoccia A., Bertini M., Loffi M., Sergio P., Andreini D., Pontone G., Iannopollo G., Nannini T., Ippolito D., Bellani G., Patelli G., Besana F., Vignali L., Sverzellati N., Iannaccone M., Vaudano P. G., Sangiorgi G. M., Turchio P., Monello A., Tumminello G., Maggioni A. P., Rapezzi C., Colombo A., Giannini F., Esposito A., Cereda, A, Toselli, M, Palmisano, A, Vignale, D, Leone, R, Nicoletti, V, Gnasso, C, Mangieri, A, Khokhar, A, Campo, G, Scoccia, A, Bertini, M, Loffi, M, Sergio, P, Andreini, D, Pontone, G, Iannopollo, G, Nannini, T, Ippolito, D, Bellani, G, Patelli, G, Besana, F, Vignali, L, Sverzellati, N, Iannaccone, M, Vaudano, P, Sangiorgi, G, Turchio, P, Monello, A, Tumminello, G, Maggioni, A, Rapezzi, C, Colombo, A, Giannini, F, Esposito, A, Cereda A., Toselli M., Palmisano A., Vignale D., Leone R., Nicoletti V., Gnasso C., Mangieri A., Khokhar A., Campo G., Scoccia A., Bertini M., Loffi M., Sergio P., Andreini D., Pontone G., Iannopollo G., Nannini T., Ippolito D., Bellani G., Patelli G., Besana F., Vignali L., Sverzellati N., Iannaccone M., Vaudano P. G., Sangiorgi G. M., Turchio P., Monello A., Tumminello G., Maggioni A. P., Rapezzi C., Colombo A., Giannini F., and Esposito A.

Abstract

Recent clinical and demographical studies on COVID-19 patients have demonstrated that men experience worse outcomes than women. However, in most cases, the data were not stratified according to gender, limiting the understanding of the real impact of gender on outcomes. This study aimed to evaluate the disaggregated in-hospital outcomes and explore the possible interactions between gender and cardiovascular calcifications. Data was derived from the sCORE-COVID-19 registry, an Italian multicentre registry that enrolled COVID-19 patients who had undergone a chest computer tomography scan on admission. A total of 1683 hospitalized patients (mean age 67±14 years) were included. Men had a higher prevalence of cardiovascular comorbidities, a higher pneumonia extension, more coronary calcifications (63% vs.50.9%, p<0.001), and a higher coronary calcium score (391±847 vs. 171±479 mm3, p<0.001). Men experienced a significantly higher mortality rate (24.4% vs. 17%, p=0.001), but the death event tended to occur earlier in women (15±7 vs. 8±7 days, p= 0.07). Non-survivors had a higher coronary, thoracic aorta, and aortic valve calcium score. Female sex, a known independent predictor of a favorable outcome in SARS-CoV2 infection, was not protective in women with a coronary calcification volume greater than 100 mm3. There were significant differences in cardiovascular comorbidities and vascular calcifications between men and women with SARS-CoV2 pneumonia. The differences in outcomes can be at least partially explained by the different cardiovascular profiles. However, women with poor outcomes had the same coronary calcific burden as men. The presumed favorable female sex bias in COVID-19 must therefore be reviewed in the context of comorbidities, especially cardiovascular ones.

Published
2021

28. Impact of clinical and subclinical coronary artery disease as assessed by coronary artery calcium in COVID-19

Author

Scoccia, A, Gallone, G, Cereda, A, Palmisano, A, Vignale, D, Leone, R, Nicoletti, V, Gnasso, C, Monello, A, Khokhar, A, Sticchi, A, Biagi, A, Tacchetti, C, Campo, G, Rapezzi, C, Ponticelli, F, Danzi, G, Loffi, M, Pontone, G, Andreini, D, Casella, G, Iannopollo, G, Ippolito, D, Bellani, G, Patelli, G, Besana, F, Costa, C, Vignali, L, Benatti, G, Iannaccone, M, Vaudano, P, Pacielli, A, De Carlini, C, Maggiolini, S, Bonaffini, P, Senni, M, Scarnecchia, E, Anastasio, F, Colombo, A, Ferrari, R, Esposito, A, Giannini, F, Toselli, M, Scoccia A., Gallone G., Cereda A., Palmisano A., Vignale D., Leone R., Nicoletti V., Gnasso C., Monello A., Khokhar A., Sticchi A., Biagi A., Tacchetti C., Campo G., Rapezzi C., Ponticelli F., Danzi G. B., Loffi M., Pontone G., Andreini D., Casella G., Iannopollo G., Ippolito D., Bellani G., Patelli G., Besana F., Costa C., Vignali L., Benatti G., Iannaccone M., Vaudano P. G., Pacielli A., De Carlini C. C., Maggiolini S., Bonaffini P. A., Senni M., Scarnecchia E., Anastasio F., Colombo A., Ferrari R., Esposito A., Giannini F., Toselli M., Scoccia, A, Gallone, G, Cereda, A, Palmisano, A, Vignale, D, Leone, R, Nicoletti, V, Gnasso, C, Monello, A, Khokhar, A, Sticchi, A, Biagi, A, Tacchetti, C, Campo, G, Rapezzi, C, Ponticelli, F, Danzi, G, Loffi, M, Pontone, G, Andreini, D, Casella, G, Iannopollo, G, Ippolito, D, Bellani, G, Patelli, G, Besana, F, Costa, C, Vignali, L, Benatti, G, Iannaccone, M, Vaudano, P, Pacielli, A, De Carlini, C, Maggiolini, S, Bonaffini, P, Senni, M, Scarnecchia, E, Anastasio, F, Colombo, A, Ferrari, R, Esposito, A, Giannini, F, Toselli, M, Scoccia A., Gallone G., Cereda A., Palmisano A., Vignale D., Leone R., Nicoletti V., Gnasso C., Monello A., Khokhar A., Sticchi A., Biagi A., Tacchetti C., Campo G., Rapezzi C., Ponticelli F., Danzi G. B., Loffi M., Pontone G., Andreini D., Casella G., Iannopollo G., Ippolito D., Bellani G., Patelli G., Besana F., Costa C., Vignali L., Benatti G., Iannaccone M., Vaudano P. G., Pacielli A., De Carlini C. C., Maggiolini S., Bonaffini P. A., Senni M., Scarnecchia E., Anastasio F., Colombo A., Ferrari R., Esposito A., Giannini F., and Toselli M.

Abstract

Background and aims: The potential impact of coronary atherosclerosis, as detected by coronary artery calcium, on clinical outcomes in COVID-19 patients remains unsettled. We aimed to evaluate the prognostic impact of clinical and subclinical coronary artery disease (CAD), as assessed by coronary artery calcium score (CAC), in a large, unselected population of hospitalized COVID-19 patients undergoing non-gated chest computed tomography (CT) for clinical practice. Methods: SARS-CoV 2 positive patients from the multicenter (16 Italian hospitals), retrospective observational SCORE COVID-19 (calcium score for COVID-19 Risk Evaluation) registry were stratified in three groups: (a) “clinical CAD” (prior revascularization history), (b) “subclinical CAD” (CAC >0), (c) “No CAD” (CAC = 0). Primary endpoint was in-hospital mortality and the secondary endpoint was a composite of myocardial infarction and cerebrovascular accident (MI/CVA). Results: Amongst 1625 patients (male 67.2%, median age 69 [interquartile range 58–77] years), 31%, 57.8% and 11.1% had no, subclinical and clinical CAD, respectively. Increasing rates of in-hospital mortality (11.3% vs. 27.3% vs. 39.8%, p < 0.001) and MI/CVA events (2.3% vs. 3.8% vs. 11.9%, p < 0.001) were observed for patients with no CAD vs. subclinical CAD vs clinical CAD, respectively. The association with in-hospital mortality was independent of in-study outcome predictors (age, peripheral artery disease, active cancer, hemoglobin, C-reactive protein, LDH, aerated lung volume): subclinical CAD vs. No CAD: adjusted hazard ratio (adj-HR) 2.86 (95% confidence interval [CI] 1.14–7.17, p=0.025); clinical CAD vs. No CAD: adj-HR 3.74 (95% CI 1.21–11.60, p=0.022). Among patients with subclinical CAD, increasing CAC burden was associated with higher rates of in-hospital mortality (20.5% vs. 27.9% vs. 38.7% for patients with CAC score thresholds≤100, 101–400 and > 400, respectively, p < 0.001). The adj-HR per 50 points increase in C

Published
2021

29. COMPASS criteria applied to a contemporary cohort of unselected patients with stable coronary artery diseases: Insights from the STARTregistry

Author

De Luca, L, Formigli, D, Meessen, J, Uguccioni, M, Cosentino, N, Paolillo, C, Di Lenarda, A, Colivicchi, F, Gabrielli, D, Gulizia, M, Scherillo, M, Maras, P, Ramani, F, Falcone, C, Passarelli, I, Mauri, S, Calabro, P, Bianchi, R, Di Palma, G, Mascia, F, Vetrano, A, Fusco, A, Proia, E, Aiello, A, Tomai, F, Licitra, R, Petrolini, A, Bosco, B, Magliari, F, Callerame, M, Mazzella, T, Lettica, G, Coco, G, Incao, F, Marinacci, L, D'Addario, S, Tartaglione, S, Ubaldi, S, Sanchez, F, Costa, P, Manca, G, Failla, M, Procaccini, V, Senni, M, Luminita, E, Bonomo, P, Mossa, C, Corda, S, Colavita, A, Trevisonno, G, Vizzari, G, Formaro, C, Nalin, I, De Rosa, F, Fontana, F, Fuscaldo, G, Passamonti, E, Bertella, E, Calvaruso, E, Varani, E, Tani, F, Cicchitelli, G, Paoloni, P, Marziali, A, Campo, G, Tebaldi, M, Biscaglia, S, Di Biase, M, Brunetti, N, Gallotta, A, Mattei, L, Marini, R, Balsemin, F, D'Urbano, M, Naio, R, Vicinelli, P, Arena, G, Mazzini, M, Gigli, N, Miserrafiti, B, Monopoli, A, Mortara, A, Delfino, P, Chioffi, M, Marino, P, Gravellone, M, Barbieri, L, Ledda, A, Geraci, G, Carmina, M, Raisaro, A, Di Giacomo, C, Somaschini, A, Fasano, M, Sannazzaro, M, Arcieri, R, Pantaleoni, M, Leuzzi, C, Gorlato, G, Greco, G, Chiera, A, Ammaturo, T, Malanchini, G, Del Corral, M, Tedesco, L, Pede, S, Urso, L, Piscione, F, Galasso, G, Provasoli, S, Fattore, L, Lucca, G, Cresti, A, Cardillo, A, Fera, M, Vennettilli, F, Gaudio, C, Paravati, V, Caldarola, P, Locuratolo, N, Verlato, R, De Conti, F, Turiano, G, Preti, G, Moretti, L, Silenzi, S, Colonna, G, Picciolo, A, Nicosia, A, Cascone, C, Di Sciascio, G, Mangiacapra, F, Russo, A, Mastroianno, S, Esposito, G, Cosmi, F, D'Orazio, S, Costantini, C, Lanari, A, De Rosa, P, Esposito, L, Bilato, C, Dalla Valle, C, Ceresa, M, Colombo, E, Pennisi, V, Casciola, G, Driussi, M, Bisceglia, T, Scalvini, S, Rivadossi, F, Volpe, M, Comito, F, Scorzoni, D, Grimoldi, P, Lagioia, R, Santoro, D, De Cesare, N, Comotti, T, Poli, A, Martina, P, Musolino, M, Multari, E, Bilardo, G, Scalchi, G, Olivieri, C, Caranci, F, Pavan, D, Ganci, G, Mariani, A, Falchetti, E, Lanzillo, T, Caccavale, A, Bongo, A, Rizzi, A, Favilli, R, Maffei, S, Mallardo, M, Fulgione, C, Bordin, F, Bonmassari, R, Battaia, E, Puzzo, A, Vianello, G, D'Arpino, A, Romei, M, Pajes, G, Petronzelli, S, Ghezzi, F, Brigido, S, Pignatelli, L, Brscic, E, Sori, P, Russo, M, Biancolillo, E, Ignone, G, De Giorgio, N, Campaniello, C, Ponticelli, P, Margonato, A, Gerosa, S, Cutaia, A, Casalicchio, C, Bartolomucci, F, Larosa, C, Spadafina, T, Putignano, A, Se Cristofaro, R, Bernardi, L, Sommariva, L, Celestini, A, Bertucci, C, Marchetti, M, Franceschini Grisolia, E, Ammendolea, C, Carini, M, Scipione, P, Politano, M, Rubino, G, Reina, C, Peccerillo, N, Paloscia, L, D'Alleva, A, Petacchi, R, Pignalosa, M, Lucchetti, D, Di Palma, F, La Mastra, R, Amico, A, De Filippis, M, Fontanella, B, Zanini, G, Casolo, G, Del Meglio, J, Parato, V, Genovesi, E, D'Alimonte, A, Miglioranza, A, Alessandri, N, Moscariello, F, Mauro, C, Sasso, A, Caso, P, Petrillo, C, Napoletano, C, Paparoni, S, Bernardo, V, Serdoz, R, Rotunno, R, Oppo, I, Aloisio, A, Aurelio, A, Licciardello, G, Cassaniti, L, Francese, G, Marcassa, C, Temporelli, P, Villani, R, Zorzoli, F, Mileto, F, De Vecchis, M, Scolozzi, D, Lupi, G, Caruso, D, Rebulla, E, La Fata, B, Anselmi, M, Girardi, P, Borruso, E, Ferrantelli, G, Sassone, B, Bressan, S, Capriolo, M, Pelissero, E, Piancastelli, M, Gobbi, M, Cocco, F, Bruno, M, Berti, S, Lo Surdo, G, Tanzi, P, De Rosa, R, Vilei, E, De Iaco, M, Grassi, G, Zanella, C, Marullo, L, Alfano, G, Pelaggi, P, Talarico, R, Tuccillo, B, Irace, L, Proietti, F, Di Croce, G, Di Lorenzo, L, Zarrilli, A, Bongini, M, Ranise, A, Aprile, A, Fornengo, C, Capogrosso, V, Tranghese, A, Golia, B, Marziano, A, Roncon, L, Picariello, C, Bagni, E, Leci, E, Gregorio, G, Gatto, F, Piemonte, F, Gervasio, F, Navazio, A, Guerri, E, Belmonte, E, Marino, F, Di Belardino, N, Di Nuzzo, M, Epifani, M, Comolatti, G, Conconi, B, Benea, D, Casu, G, Merella, P, Ammirati, M, Corrado, V, Spagnolo, D, Caico, S, Bonizzato, S, Margheri, M, Corrado, L, Antonicelli, R, Ferrigno, C, Merlino, A, Nassiacos, D, Antonelli, A, Marchese, A, Villella, A, Bechi, S, Lo Bianco, F, Bedogni, F, Negro, L, Donato, L, Statile, D, Cassin, M, Fedele, F, Granatelli, A, Calcagno, S, Politi, A, Pani, A, De Luca L., Formigli D., Meessen J., Uguccioni M., Cosentino N., Paolillo C., Di Lenarda A., Colivicchi F., Gabrielli D., Gulizia M. M., Scherillo M., Maras P., Ramani F., Falcone C., Passarelli I., Mauri S., Calabro P., Bianchi R., Di Palma G., Mascia F., Vetrano A., Fusco A., Proia E., Aiello A., Tomai F., Licitra R., Petrolini A., Bosco B., Magliari F., Callerame M., Mazzella T., Lettica G. V., Coco G., Incao F., Marinacci L., D'Addario S., Tartaglione S. N., Ubaldi S., Sanchez F. A., Costa P., Manca G., Failla M., Procaccini V., Senni M., Luminita E. M., Bonomo P., Mossa C., Corda S., Colavita A. R., Trevisonno G., Vizzari G., Formaro C., Nalin I. L., De Rosa F. M., Fontana F., Fuscaldo G. F., Passamonti E., Bertella E., Calvaruso E. V., Varani E., Tani F., Cicchitelli G., Paoloni P., Marziali A., Campo G., Tebaldi M., Biscaglia S., Di Biase M., Brunetti N. D., Gallotta A. M., Mattei L., Marini R., Balsemin F., D'Urbano M., Naio R., Vicinelli P., Arena G., Mazzini M., Gigli N., Miserrafiti B., Monopoli A., Mortara A., Delfino P., Chioffi M. M., Marino P., Gravellone M., Barbieri L., Ledda A., Geraci G., Carmina M. G., Raisaro A. E., Di Giacomo C., Somaschini A., Fasano M. L., Sannazzaro M., Arcieri R., Pantaleoni M., Leuzzi C., Gorlato G., Greco G., Chiera A., Ammaturo T. A., Malanchini G., Del Corral M. P., Tedesco L., Pede S., Urso L. G., Piscione F., Galasso G., Provasoli S., Fattore L., Lucca G., Cresti A., Cardillo A., Fera M. S., Vennettilli F., Gaudio C., Paravati V., Caldarola P., Locuratolo N., Verlato R., De Conti F., Turiano G., Preti G., Moretti L., Silenzi S., Colonna G., Picciolo A., Nicosia A., Cascone C., Di Sciascio G., Mangiacapra F., Russo A., Mastroianno S., Esposito G., Cosmi F., D'Orazio S., Costantini C., Lanari A., De Rosa P., Esposito L., Bilato C., Dalla Valle C., Ceresa M., Colombo E., Pennisi V., Casciola G., Driussi M., Bisceglia T., Scalvini S., Rivadossi F., Volpe M., Comito F., Scorzoni D., Grimoldi P., Lagioia R., Santoro D., De Cesare N., Comotti T., Poli A., Martina P., Musolino M. F., Multari E. I., Bilardo G., Scalchi G., Olivieri C., Caranci F., Pavan D., Ganci G., Mariani A., Falchetti E., Lanzillo T., Caccavale A., Bongo A. S., Rizzi A., Favilli R., Maffei S., Mallardo M., Fulgione C., Bordin F., Bonmassari R., Battaia E., Puzzo A., Vianello G., D'Arpino A., Romei M., Pajes G., Petronzelli S., Ghezzi F., Brigido S., Pignatelli L., Brscic E., Sori P., Russo M., Biancolillo E., Ignone G., De Giorgio N. A., Campaniello C., Ponticelli P., Margonato A., Gerosa S., Cutaia A., Casalicchio C., Bartolomucci F., Larosa C., Spadafina T., Putignano A., Se Cristofaro R., Bernardi L., Sommariva L., Celestini A., Bertucci C. M., Marchetti M., Franceschini Grisolia E., Ammendolea C., Carini M., Scipione P., Politano M., Rubino G., Reina C., Peccerillo N., Paloscia L., D'Alleva A., Petacchi R., Pignalosa M., Lucchetti D., Di Palma F., La Mastra R. A., Amico A. F., De Filippis M., Fontanella B., Zanini G., Casolo G., Del Meglio J., Parato V. M., Genovesi E., D'Alimonte A., Miglioranza A., Alessandri N., Moscariello F., Mauro C., Sasso A., Caso P., Petrillo C., Napoletano C., Paparoni S. R., Bernardo V., Serdoz R., Rotunno R., Oppo I., Aloisio A., Aurelio A., Licciardello G., Cassaniti L., Francese G. M., Marcassa C., Temporelli P. L., Villani R., Zorzoli F., Mileto F., De Vecchis M., Scolozzi D., Lupi G., Caruso D., Rebulla E., La Fata B., Anselmi M., Girardi P., Borruso E., Ferrantelli G., Sassone B., Bressan S., Capriolo M., Pelissero E., Piancastelli M., Gobbi M., Cocco F., Bruno M. G., Berti S., Lo Surdo G., Tanzi P., De Rosa R., Vilei E., De Iaco M. R., Grassi G., Zanella C., Marullo L., Alfano G., Pelaggi P., Talarico R., Tuccillo B., Irace L., Proietti F., Di Croce G., Di Lorenzo L., Zarrilli A., Bongini M., Ranise A., Aprile A., Fornengo C., Capogrosso V., Tranghese A., Golia B., Marziano A., Roncon L., Picariello C., Bagni E., Leci E., Gregorio G., Gatto F., Piemonte F., Gervasio F., Navazio A., Guerri E., Belmonte E., Marino F., Di Belardino N., Di Nuzzo M. R., Epifani M., Comolatti G., Conconi B., Benea D., Casu G., Merella P., Ammirati M. A., Corrado V. M., Spagnolo D., Caico S. I., Bonizzato S., Margheri M., Corrado L., Antonicelli R., Ferrigno C., Merlino A., Nassiacos D., Antonelli A., Marchese A., Villella A., Bechi S., Lo Bianco F., Bedogni F., Negro L., Donato L., Statile D., Cassin M., Fedele F., Granatelli A., Calcagno S., Politi A., Pani A., De Luca, L, Formigli, D, Meessen, J, Uguccioni, M, Cosentino, N, Paolillo, C, Di Lenarda, A, Colivicchi, F, Gabrielli, D, Gulizia, M, Scherillo, M, Maras, P, Ramani, F, Falcone, C, Passarelli, I, Mauri, S, Calabro, P, Bianchi, R, Di Palma, G, Mascia, F, Vetrano, A, Fusco, A, Proia, E, Aiello, A, Tomai, F, Licitra, R, Petrolini, A, Bosco, B, Magliari, F, Callerame, M, Mazzella, T, Lettica, G, Coco, G, Incao, F, Marinacci, L, D'Addario, S, Tartaglione, S, Ubaldi, S, Sanchez, F, Costa, P, Manca, G, Failla, M, Procaccini, V, Senni, M, Luminita, E, Bonomo, P, Mossa, C, Corda, S, Colavita, A, Trevisonno, G, Vizzari, G, Formaro, C, Nalin, I, De Rosa, F, Fontana, F, Fuscaldo, G, Passamonti, E, Bertella, E, Calvaruso, E, Varani, E, Tani, F, Cicchitelli, G, Paoloni, P, Marziali, A, Campo, G, Tebaldi, M, Biscaglia, S, Di Biase, M, Brunetti, N, Gallotta, A, Mattei, L, Marini, R, Balsemin, F, D'Urbano, M, Naio, R, Vicinelli, P, Arena, G, Mazzini, M, Gigli, N, Miserrafiti, B, Monopoli, A, Mortara, A, Delfino, P, Chioffi, M, Marino, P, Gravellone, M, Barbieri, L, Ledda, A, Geraci, G, Carmina, M, Raisaro, A, Di Giacomo, C, Somaschini, A, Fasano, M, Sannazzaro, M, Arcieri, R, Pantaleoni, M, Leuzzi, C, Gorlato, G, Greco, G, Chiera, A, Ammaturo, T, Malanchini, G, Del Corral, M, Tedesco, L, Pede, S, Urso, L, Piscione, F, Galasso, G, Provasoli, S, Fattore, L, Lucca, G, Cresti, A, Cardillo, A, Fera, M, Vennettilli, F, Gaudio, C, Paravati, V, Caldarola, P, Locuratolo, N, Verlato, R, De Conti, F, Turiano, G, Preti, G, Moretti, L, Silenzi, S, Colonna, G, Picciolo, A, Nicosia, A, Cascone, C, Di Sciascio, G, Mangiacapra, F, Russo, A, Mastroianno, S, Esposito, G, Cosmi, F, D'Orazio, S, Costantini, C, Lanari, A, De Rosa, P, Esposito, L, Bilato, C, Dalla Valle, C, Ceresa, M, Colombo, E, Pennisi, V, Casciola, G, Driussi, M, Bisceglia, T, Scalvini, S, Rivadossi, F, Volpe, M, Comito, F, Scorzoni, D, Grimoldi, P, Lagioia, R, Santoro, D, De Cesare, N, Comotti, T, Poli, A, Martina, P, Musolino, M, Multari, E, Bilardo, G, Scalchi, G, Olivieri, C, Caranci, F, Pavan, D, Ganci, G, Mariani, A, Falchetti, E, Lanzillo, T, Caccavale, A, Bongo, A, Rizzi, A, Favilli, R, Maffei, S, Mallardo, M, Fulgione, C, Bordin, F, Bonmassari, R, Battaia, E, Puzzo, A, Vianello, G, D'Arpino, A, Romei, M, Pajes, G, Petronzelli, S, Ghezzi, F, Brigido, S, Pignatelli, L, Brscic, E, Sori, P, Russo, M, Biancolillo, E, Ignone, G, De Giorgio, N, Campaniello, C, Ponticelli, P, Margonato, A, Gerosa, S, Cutaia, A, Casalicchio, C, Bartolomucci, F, Larosa, C, Spadafina, T, Putignano, A, Se Cristofaro, R, Bernardi, L, Sommariva, L, Celestini, A, Bertucci, C, Marchetti, M, Franceschini Grisolia, E, Ammendolea, C, Carini, M, Scipione, P, Politano, M, Rubino, G, Reina, C, Peccerillo, N, Paloscia, L, D'Alleva, A, Petacchi, R, Pignalosa, M, Lucchetti, D, Di Palma, F, La Mastra, R, Amico, A, De Filippis, M, Fontanella, B, Zanini, G, Casolo, G, Del Meglio, J, Parato, V, Genovesi, E, D'Alimonte, A, Miglioranza, A, Alessandri, N, Moscariello, F, Mauro, C, Sasso, A, Caso, P, Petrillo, C, Napoletano, C, Paparoni, S, Bernardo, V, Serdoz, R, Rotunno, R, Oppo, I, Aloisio, A, Aurelio, A, Licciardello, G, Cassaniti, L, Francese, G, Marcassa, C, Temporelli, P, Villani, R, Zorzoli, F, Mileto, F, De Vecchis, M, Scolozzi, D, Lupi, G, Caruso, D, Rebulla, E, La Fata, B, Anselmi, M, Girardi, P, Borruso, E, Ferrantelli, G, Sassone, B, Bressan, S, Capriolo, M, Pelissero, E, Piancastelli, M, Gobbi, M, Cocco, F, Bruno, M, Berti, S, Lo Surdo, G, Tanzi, P, De Rosa, R, Vilei, E, De Iaco, M, Grassi, G, Zanella, C, Marullo, L, Alfano, G, Pelaggi, P, Talarico, R, Tuccillo, B, Irace, L, Proietti, F, Di Croce, G, Di Lorenzo, L, Zarrilli, A, Bongini, M, Ranise, A, Aprile, A, Fornengo, C, Capogrosso, V, Tranghese, A, Golia, B, Marziano, A, Roncon, L, Picariello, C, Bagni, E, Leci, E, Gregorio, G, Gatto, F, Piemonte, F, Gervasio, F, Navazio, A, Guerri, E, Belmonte, E, Marino, F, Di Belardino, N, Di Nuzzo, M, Epifani, M, Comolatti, G, Conconi, B, Benea, D, Casu, G, Merella, P, Ammirati, M, Corrado, V, Spagnolo, D, Caico, S, Bonizzato, S, Margheri, M, Corrado, L, Antonicelli, R, Ferrigno, C, Merlino, A, Nassiacos, D, Antonelli, A, Marchese, A, Villella, A, Bechi, S, Lo Bianco, F, Bedogni, F, Negro, L, Donato, L, Statile, D, Cassin, M, Fedele, F, Granatelli, A, Calcagno, S, Politi, A, Pani, A, De Luca L., Formigli D., Meessen J., Uguccioni M., Cosentino N., Paolillo C., Di Lenarda A., Colivicchi F., Gabrielli D., Gulizia M. M., Scherillo M., Maras P., Ramani F., Falcone C., Passarelli I., Mauri S., Calabro P., Bianchi R., Di Palma G., Mascia F., Vetrano A., Fusco A., Proia E., Aiello A., Tomai F., Licitra R., Petrolini A., Bosco B., Magliari F., Callerame M., Mazzella T., Lettica G. V., Coco G., Incao F., Marinacci L., D'Addario S., Tartaglione S. N., Ubaldi S., Sanchez F. A., Costa P., Manca G., Failla M., Procaccini V., Senni M., Luminita E. M., Bonomo P., Mossa C., Corda S., Colavita A. R., Trevisonno G., Vizzari G., Formaro C., Nalin I. L., De Rosa F. M., Fontana F., Fuscaldo G. F., Passamonti E., Bertella E., Calvaruso E. V., Varani E., Tani F., Cicchitelli G., Paoloni P., Marziali A., Campo G., Tebaldi M., Biscaglia S., Di Biase M., Brunetti N. D., Gallotta A. M., Mattei L., Marini R., Balsemin F., D'Urbano M., Naio R., Vicinelli P., Arena G., Mazzini M., Gigli N., Miserrafiti B., Monopoli A., Mortara A., Delfino P., Chioffi M. M., Marino P., Gravellone M., Barbieri L., Ledda A., Geraci G., Carmina M. G., Raisaro A. E., Di Giacomo C., Somaschini A., Fasano M. L., Sannazzaro M., Arcieri R., Pantaleoni M., Leuzzi C., Gorlato G., Greco G., Chiera A., Ammaturo T. A., Malanchini G., Del Corral M. P., Tedesco L., Pede S., Urso L. G., Piscione F., Galasso G., Provasoli S., Fattore L., Lucca G., Cresti A., Cardillo A., Fera M. S., Vennettilli F., Gaudio C., Paravati V., Caldarola P., Locuratolo N., Verlato R., De Conti F., Turiano G., Preti G., Moretti L., Silenzi S., Colonna G., Picciolo A., Nicosia A., Cascone C., Di Sciascio G., Mangiacapra F., Russo A., Mastroianno S., Esposito G., Cosmi F., D'Orazio S., Costantini C., Lanari A., De Rosa P., Esposito L., Bilato C., Dalla Valle C., Ceresa M., Colombo E., Pennisi V., Casciola G., Driussi M., Bisceglia T., Scalvini S., Rivadossi F., Volpe M., Comito F., Scorzoni D., Grimoldi P., Lagioia R., Santoro D., De Cesare N., Comotti T., Poli A., Martina P., Musolino M. F., Multari E. I., Bilardo G., Scalchi G., Olivieri C., Caranci F., Pavan D., Ganci G., Mariani A., Falchetti E., Lanzillo T., Caccavale A., Bongo A. S., Rizzi A., Favilli R., Maffei S., Mallardo M., Fulgione C., Bordin F., Bonmassari R., Battaia E., Puzzo A., Vianello G., D'Arpino A., Romei M., Pajes G., Petronzelli S., Ghezzi F., Brigido S., Pignatelli L., Brscic E., Sori P., Russo M., Biancolillo E., Ignone G., De Giorgio N. A., Campaniello C., Ponticelli P., Margonato A., Gerosa S., Cutaia A., Casalicchio C., Bartolomucci F., Larosa C., Spadafina T., Putignano A., Se Cristofaro R., Bernardi L., Sommariva L., Celestini A., Bertucci C. M., Marchetti M., Franceschini Grisolia E., Ammendolea C., Carini M., Scipione P., Politano M., Rubino G., Reina C., Peccerillo N., Paloscia L., D'Alleva A., Petacchi R., Pignalosa M., Lucchetti D., Di Palma F., La Mastra R. A., Amico A. F., De Filippis M., Fontanella B., Zanini G., Casolo G., Del Meglio J., Parato V. M., Genovesi E., D'Alimonte A., Miglioranza A., Alessandri N., Moscariello F., Mauro C., Sasso A., Caso P., Petrillo C., Napoletano C., Paparoni S. R., Bernardo V., Serdoz R., Rotunno R., Oppo I., Aloisio A., Aurelio A., Licciardello G., Cassaniti L., Francese G. M., Marcassa C., Temporelli P. L., Villani R., Zorzoli F., Mileto F., De Vecchis M., Scolozzi D., Lupi G., Caruso D., Rebulla E., La Fata B., Anselmi M., Girardi P., Borruso E., Ferrantelli G., Sassone B., Bressan S., Capriolo M., Pelissero E., Piancastelli M., Gobbi M., Cocco F., Bruno M. G., Berti S., Lo Surdo G., Tanzi P., De Rosa R., Vilei E., De Iaco M. R., Grassi G., Zanella C., Marullo L., Alfano G., Pelaggi P., Talarico R., Tuccillo B., Irace L., Proietti F., Di Croce G., Di Lorenzo L., Zarrilli A., Bongini M., Ranise A., Aprile A., Fornengo C., Capogrosso V., Tranghese A., Golia B., Marziano A., Roncon L., Picariello C., Bagni E., Leci E., Gregorio G., Gatto F., Piemonte F., Gervasio F., Navazio A., Guerri E., Belmonte E., Marino F., Di Belardino N., Di Nuzzo M. R., Epifani M., Comolatti G., Conconi B., Benea D., Casu G., Merella P., Ammirati M. A., Corrado V. M., Spagnolo D., Caico S. I., Bonizzato S., Margheri M., Corrado L., Antonicelli R., Ferrigno C., Merlino A., Nassiacos D., Antonelli A., Marchese A., Villella A., Bechi S., Lo Bianco F., Bedogni F., Negro L., Donato L., Statile D., Cassin M., Fedele F., Granatelli A., Calcagno S., Politi A., and Pani A.

Abstract

Aims Recently, the cardiovascular outcomes for people using anticoagulation strategies (COMPASS) trial demonstrated that dual therapy reduced cardiovascular outcomes compared with aspirin alone in patients with stable atherosclerotic disease. Methods and We sought to assess the proportion of patients eligible for the COMPASS trial and to compare the epidemiology results and outcome of these patients with those without COMPASS inclusion or with any exclusion criteria in a contemporary, nationwide cohort of patients with stable coronary artery disease. Among the 4068 patients with detailed information allowing evaluation of eligibility, 1416 (34.8%) did not fulfil the inclusion criteria (COMPASS-Not-Included), 841 (20.7%) had exclusion criteria (COMPASS-Excluded), and the remaining 1811 (44.5%) were classified as COMPASS-Like. At 1 year, the incidence of major adverse cardiovascular event (MACE), a composite of cardiovascular death, myocardial infarction, and stroke, was 0.9% in the COMPASS-Not-Included and 2.0% in the COMPASS-Like (P = 0.01), and 5.0% in the COMPASS-Excluded group (P < 0.0001 for all comparisons). Among the COMPASS-Like population, patients with multiple COMPASS enrichment criteria presented a significant increase in the risk of MACE (from 1.0% to 3.3% in those with 1 and >_3 criteria, respectively; P = 0.012), and a modest absolute increase in major bleeding risk (from 0.2% to 0.4%, respectively; P = 0.46). Conclusion In a contemporary real-world cohort registry of stable coronary artery disease, most patients resulted as eligible for the COMPASS. These patients presented a considerable annual risk of MACE that consistently increases in the presence of multiple risk factors.

Published
2021

30. Current evidence on the diagnostic and prognostic role of native T1 mapping in heart diseases

Author

Tonet, E, Baggiano, A, Pavasini, R, Guglielmo, M, Censi, S, Cossu, A, Rapezzi, C, Muscogiuri, G, Squeri, A, Campo, G, Pontone, G, Tonet E, Baggiano A, Pavasini R, Guglielmo M, Censi S, Cossu A, Rapezzi C, Muscogiuri G, Squeri A, Campo G, Pontone G., Tonet, E, Baggiano, A, Pavasini, R, Guglielmo, M, Censi, S, Cossu, A, Rapezzi, C, Muscogiuri, G, Squeri, A, Campo, G, Pontone, G, Tonet E, Baggiano A, Pavasini R, Guglielmo M, Censi S, Cossu A, Rapezzi C, Muscogiuri G, Squeri A, Campo G, and Pontone G.

Abstract

Tissue characterization represents a prerogative of cardiac magnetic resonance. Beside late gadolinium enhancement, native T1 mapping (nT1m) reveals tissue composition. It could represent a useful tool for example when contrast medium can't be administrated. The present review summarises current evidence about nT1m in main heart diseases.

Published
2021

31. Is pleural effusion in COVID-19 interstitial pneumonia related to in-hospital mortality?

Author

Cereda, A, Toselli, M, Palmisano, A, Leone, R, Vignale, D, Nicoletti, V, Campo, G, Monello, A, Ippolito, D, Giannini, F, Esposito, A, Cereda A., Toselli M., Palmisano A., Leone R., Vignale D., Nicoletti V., Campo G., Monello A., Ippolito D., Giannini F., Esposito A., Cereda, A, Toselli, M, Palmisano, A, Leone, R, Vignale, D, Nicoletti, V, Campo, G, Monello, A, Ippolito, D, Giannini, F, Esposito, A, Cereda A., Toselli M., Palmisano A., Leone R., Vignale D., Nicoletti V., Campo G., Monello A., Ippolito D., Giannini F., and Esposito A.

Abstract

The recent severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) pandemic has highlighted the importance of pulmonary computed tomography (CT) for diagnosis and prognostic stratification of this new viral pneumonia. 1370 lung CT scans (performed at the time of admission) of consecutive patients hospitalized for SARS-CoV-2 in Northern Italy during the first epidemic wave were analyzed by a radiological CoreLab. The presence of pleural effusion on pulmonary CT scan was present in 188 patients (13.3% of the population) and identified a population with more comorbidities. Patients with pleural effusion had more cardio-respiratory complications with higher mortality. Pleural effusion was an independent predictor of death on multivariate analysis with an HR of 1.4 (95% confidence interval 1-1.9). Pulmonary CT pleural effusion was an independent predictor of mortality.

Published
2021

32. Coronary access following ACURATE neo implantation for ViV-TAVI: ex vivo analysis in patient-specific anatomies

Author

Khokhar, AA, Ponticelli, F, Zlahoda-Huzior, A, Chandra, K, Ruggiero, R, Toselli, M, Gallo, F, Cereda, A, Laricchia, A, Sticchi, A, Regazzoli, D, Mangieri, A, Reimers, B, Biscaglia, S, Tumscitz, C, Campo, G, Mikhail, G, Kim, W-K, Colombo, A, Dudek, D, and Giannini, F

Abstract

Background Coronary access after transcatheter aortic valve implantation (TAVI) with supra-annular self-expandable valves may be challenging or un-feasible. There is little data concerning coronary access following transcatheter aortic valve-in-valve implantation (ViV-TAVI) for degenerated surgical bioprosthesis Aims To evaluate the feasibility and challenge of coronary access after ViV-TAVI with the supra-annular self-expandable ACURATE neo valve. Methods Sixteen patients underwent ViV-TAVI with the ACURATE neo valve. Post-procedural computed tomography (CT) was used to create 3D-printed life-sized patient-specific models for bench-testing of coronary cannulation. Primary endpoint was feasibility of diagnostic angiography and PCI. Secondary endpoints included incidence of challenging cannulation for both diagnostic catheters (DC) and guiding catheters (GC). The association between challenging cannulations with aortic and transcatheter/surgical valve geometry was evaluated using pre and post-procedural CT scans. Results Diagnostic angiography and PCI were feasible for 97% and 95% of models respectively. All non-feasible procedures occurred in ostia that underwent prophylactic ‘chimney’ stenting. DC cannulation was challenging in 17% of models and was associated with a narrower SoV width (30mm vs. 35mm, p

Published
2022

33. Implications of properties and quality of indoor sensor data for building machine learning applications:two case studies in smart campuses

Author

Lillstrang, M. (Miia), Harju, M. (Markus), del Campo, G. (Guillermo), Röning, J. (Juha), Tamminen, S. (Satu), Lillstrang, M. (Miia), Harju, M. (Markus), del Campo, G. (Guillermo), Röning, J. (Juha), and Tamminen, S. (Satu)

Abstract

Sensor devices are becoming omnipresent, supplying data to a wide range of applications. In the building sector, sensors along with other information sources provide the basis for smart building functionalities. Predicting energy loads and inferring occupancy status of spaces are important tasks that promote energy efficiency and user comfort in buildings. For them, as for many other smart building applications, machine learning modelling utilizing sensor data is commonly applied. This article builds understanding of the environment where this kind of machine learning models have to operate by bringing up properties and quality aspects of the public building data provided by indoor sensor devices. This is done by performing a thorough case study on two real life data sets from university campus buildings located in different climates and applying very different sensor network settings. Outcomes include information about heterogeneity, correlations and temporal patterns present in sensor data, and show the need of the building field for better acknowledging the quality deficiencies that sensor data have. Our results aid in assessing and improving the quality of sensor-based indoor data utilized in machine learning modelling, in evaluating whether a data set is representative enough to build a model that is robust under changing conditions in the building, and in choosing an appropriate number of sensors per space when building an indoor wireless sensor network.

Published
2022

34. Intra-articular clodronate in patients with knee osteoarthritis non-responder to intra-articular hyaluronic acid - a case report series of 9 patients with 8-month follow-up.

Author

Saviola, G., Da Campo, G., Bianchini, M. C., Abdi-Ali, L., Comini, L., Rosini, S., and Molfetta, L.

Subjects
OSTEOARTHRITIS, OLDER people, DIPHOSPHONATES, LIDOCAINE, ANALGESICS
Abstract

Background. Osteoarthritis (OA) is a common disease in the elderly people, inducing pain and functional limitations. Clodronate (CLO) a first generation non-nitrogen containing bisphosphonate has been purposed as a treatment of OA, being effective on pain, inflammation, bone marrow oedema, osteophytosis and cartilage regeneration. Intramuscular routes of CLO showed efficacy in the treatment of Knee OA (KOA) and erosive OA of the hand. In KOA intraarticular CLO at low doses (0.5-2 mg) showed efficacy as well as hyaluronic acid (HA), being able to improve the effectiveness if associated to HA. Methods. Nine Consecutive patients (4 female, 5 male, mean age 78,22) with KOA at 2nd or 3rd degree following Kellgren-Lawrance scale, non responder to HA and unintended to surgery. They were treated with intraarticular CLO at the weekly dose of 20 mg, plus lidocaine 1% in 5 cc of saline solution for a route of 5 weekly infiltrations, followed by a second route of 5 intraarticular infiltrations 3 months after the first course. Visual analog score (VAS) pain and Tegner-Lysholm Score (TLS) were used to assess changes following CLO treatment. Results. Baseline pain was 6,77/10, reduced to 1,09 at day 150 (after second course) and to 2,3/10 at day 240. TLS at baseline was 56,7/100, improved to 96,7 at day 150 and to 84,1 at day 240. At day 240 only 2 out of 9 patients had a negative judgement of the treatment and decided to stop it, while 7 were satisfied and available to a further course. There was no increase of consumption of anti-inflammatory or analgesic drugs. A short time lasting pain after the injections was registered in all patients. Conclusions. In a small cohort of patients affected by KOA, non responders to intraarticular HA a higher dose of intraarticular CLO in KOA showed good compliance, amelioration of pain and functionality. [ABSTRACT FROM AUTHOR]

Published
2023
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42. Current status of Drosophila suzukii classical biological control in Italy

Author

Lisi, F., Biondi, A., Cavallaro, C., Zappalà, L., Campo, G., Roversi, P. F., Sabbatini Peverieri, G., Giovannini, L., Tavella, L., Tortorici, F., Bardella, S., Carli, C., Bosio, G., Mori, N., Tonina, L., Zanini, G., Caruso, S., Vaccari, G., Masetti, A., Bittau, B., Bariselli, M., Schmidt, S., Falagiarda, M., Bertignono, L., Bonfanti, R., Giorgini, M., Guerrieri, E., Tropiano, F. G., Verrastro, V., Baser, N., Ibn Amor, A., Endrizzi, S., Tessari, L., Puppato, S., Ioriatti, C., Grassi, A., Anfora, G., Fellin, L., Rossi, Stacconi, and M. V.

Subjects
Settore AGR/11 - ENTOMOLOGIA GENERALE E APPLICATA, importation biological control, Parasidoid, host range, IPM, Horticulture, Ganaspis brasiliensis, Ganaspis brasiliensis, host range, invasive species, importation biological control, IPM, parasitoid, parasitoid, invasive species
Published
2022

43. Complete versus culprit-only strategy in older MI patients with multivessel disease

Author

Biscaglia S, Erriquez A, Serenelli M, D'Ascenzo F, De Ferrari G, Ariza Sole A, Sanchis J, Giannini F, Gallo F, Scala A, Menozzi A, Pighi M, Moreno R, Iannopollo G, Menozzi M, Guiducci V, Tebaldi M, and Campo G

Abstract

AIMS: The revascularization strategy to pursue in older myocardial infarction (MI) patients with multivessel disease (MVD) is currently unknown. For this reason, while waiting for the results of dedicated trials, we sought to compare a complete versus a culprit-only strategy in older MI patients by merging data from four registries.; METHODS AND RESULTS: The inclusion criteria for the target population of the present study were(i) age=75 years; (ii) MI (STE or NSTE); (iii) MVD; (iv) successful treatment of culprit lesion. Propensity scores (PS) were derived using logistic regression (backwardstepwise selection, p

Published
2022

44. Screening for atrial fibrillation in the general population: experience from a cardiovascular risk campaign in the Emilia-Romagna Region|Screening della fibrillazione atriale nella popolazione generale: esperienza della campagna educazionale sul rischio cardiovascolare della Regione Emilia-Romagna

Author

Di Pasquale, G., Cardelli, L. S., Canovi, L., Dal Passo, B., Frascaro, F., Zanarelli, L., Guardigli, G., Campo, G., Aschieri, D., Vignali, L., Navazio, A., Rubboli, A., Ortolani, P., Galvani, M., Ni, M., Piovaccari, G., Tortorici, G., Urbinati, S., Tondi, S., Sassone, B., Tortorella, G., De Palma, R., Casella, G., and Boriani, G.

Subjects
Male, Stroke, Heart Disease Risk Factors, Risk Factors, Cardiovascular Diseases, Thromboembolism, Atrial Fibrillation, Humans, Female, Risk Assessment
Published
2022

46. Invasive Coronary Physiology After Stent Implantation: Another Step Toward Precision Medicine

Author

Biscaglia S., Uretsky B., Barbato E., Collet C., Onuma Y., Jeremias A., Tebaldi M., Hakeem A., Kogame N., Sonck J., Escaned J., Serruys P. W., Stone G. W., Campo G., Biscaglia, S., Uretsky, B., Barbato, E., Collet, C., Onuma, Y., Jeremias, A., Tebaldi, M., Hakeem, A., Kogame, N., Sonck, J., Escaned, J., Serruys, P. W., Stone, G. W., and Campo, G.

Subjects
coronary physiology, quantitative flow ratio, precision medicine, percutaneous coronary intervention, Coronary Artery Disease, Coronary Angiography, instantaneous wave-free ratio, NO, Fractional Flow Reserve, Myocardial, Treatment Outcome, Predictive Value of Tests, fractional flow reserve, outcome, Humans, Stents
Abstract

Intracoronary physiology is routinely used in setting the indication for percutaneous coronary intervention (PCI) but seldom in assessing procedural results. This attitude is increasingly challenged by accumulated evidence demonstrating the value of post-PCI functional assessment in predicting long-term patient outcomes. Besides fractional flow reserve, a number of new indexes recently incorporated to clinical practice, including nonhyperemic pressure and functional angiographic indexes, provide new opportunities for the physiological assessment of PCI results. Largely, the benefit of these tools is derived from longitudinal analysis of the treated vessel, which allows precise identification of the vessel segment accounting for a suboptimal functional result and enabling operators to perform accurate PCI optimization. In this document the authors review available evidence supporting why physiological assessment should be extended to immediate post-PCI with the aim of improving patient outcomes. A step-by-step guide on how available physiological tools can be used for such purpose is provided.

Published
2021

47. COMPASS criteria applied to a contemporary cohort of unselected patients with stable coronary artery diseases: Insights from the STARTregistry

Author

De Luca L., Formigli D., Meessen J., Uguccioni M., Cosentino N., Paolillo C., Di Lenarda A., Colivicchi F., Gabrielli D., Gulizia M. M., Scherillo M., Maras P., Ramani F., Falcone C., Passarelli I., Mauri S., Calabro P., Bianchi R., Di Palma G., Mascia F., Vetrano A., Fusco A., Proia E., Aiello A., Tomai F., Licitra R., Petrolini A., Bosco B., Magliari F., Callerame M., Mazzella T., Lettica G. V., Coco G., Incao F., Marinacci L., D'Addario S., Tartaglione S. N., Ubaldi S., Sanchez F. A., Costa P., Manca G., Failla M., Procaccini V., Senni M., Luminita E. M., Bonomo P., Mossa C., Corda S., Colavita A. R., Trevisonno G., Vizzari G., Formaro C., Nalin I. L., De Rosa F. M., Fontana F., Fuscaldo G. F., Passamonti E., Bertella E., Calvaruso E. V., Varani E., Tani F., Cicchitelli G., Paoloni P., Marziali A., Campo G., Tebaldi M., Biscaglia S., Di Biase M., Brunetti N. D., Gallotta A. M., Mattei L., Marini R., Balsemin F., D'Urbano M., Naio R., Vicinelli P., Arena G., Mazzini M., Gigli N., Miserrafiti B., Monopoli A., Mortara A., Delfino P., Chioffi M. M., Marino P., Gravellone M., Barbieri L., Ledda A., Geraci G., Carmina M. G., Raisaro A. E., Di Giacomo C., Somaschini A., Fasano M. L., Sannazzaro M., Arcieri R., Pantaleoni M., Leuzzi C., Gorlato G., Greco G., Chiera A., Ammaturo T. A., Malanchini G., Del Corral M. P., Tedesco L., Pede S., Urso L. G., Piscione F., Galasso G., Provasoli S., Fattore L., Lucca G., Cresti A., Cardillo A., Fera M. S., Vennettilli F., Gaudio C., Paravati V., Caldarola P., Locuratolo N., Verlato R., De Conti F., Turiano G., Preti G., Moretti L., Silenzi S., Colonna G., Picciolo A., Nicosia A., Cascone C., Di Sciascio G., Mangiacapra F., Russo A., Mastroianno S., Esposito G., Cosmi F., D'Orazio S., Costantini C., Lanari A., De Rosa P., Esposito L., Bilato C., Dalla Valle C., Ceresa M., Colombo E., Pennisi V., Casciola G., Driussi M., Bisceglia T., Scalvini S., Rivadossi F., Volpe M., Comito F., Scorzoni D., Grimoldi P., Lagioia R., Santoro D., De Cesare N., Comotti T., Poli A., Martina P., Musolino M. F., Multari E. I., Bilardo G., Scalchi G., Olivieri C., Caranci F., Pavan D., Ganci G., Mariani A., Falchetti E., Lanzillo T., Caccavale A., Bongo A. S., Rizzi A., Favilli R., Maffei S., Mallardo M., Fulgione C., Bordin F., Bonmassari R., Battaia E., Puzzo A., Vianello G., D'Arpino A., Romei M., Pajes G., Petronzelli S., Ghezzi F., Brigido S., Pignatelli L., Brscic E., Sori P., Russo M., Biancolillo E., Ignone G., De Giorgio N. A., Campaniello C., Ponticelli P., Margonato A., Gerosa S., Cutaia A., Casalicchio C., Bartolomucci F., Larosa C., Spadafina T., Putignano A., Se Cristofaro R., Bernardi L., Sommariva L., Celestini A., Bertucci C. M., Marchetti M., Franceschini Grisolia E., Ammendolea C., Carini M., Scipione P., Politano M., Rubino G., Reina C., Peccerillo N., Paloscia L., D'Alleva A., Petacchi R., Pignalosa M., Lucchetti D., Di Palma F., La Mastra R. A., Amico A. F., De Filippis M., Fontanella B., Zanini G., Casolo G., Del Meglio J., Parato V. M., Genovesi E., D'Alimonte A., Miglioranza A., Alessandri N., Moscariello F., Mauro C., Sasso A., Caso P., Petrillo C., Napoletano C., Paparoni S. R., Bernardo V., Serdoz R., Rotunno R., Oppo I., Aloisio A., Aurelio A., Licciardello G., Cassaniti L., Francese G. M., Marcassa C., Temporelli P. L., Villani R., Zorzoli F., Mileto F., De Vecchis M., Scolozzi D., Lupi G., Caruso D., Rebulla E., La Fata B., Anselmi M., Girardi P., Borruso E., Ferrantelli G., Sassone B., Bressan S., Capriolo M., Pelissero E., Piancastelli M., Gobbi M., Cocco F., Bruno M. G., Berti S., Lo Surdo G., Tanzi P., De Rosa R., Vilei E., De Iaco M. R., Grassi G., Zanella C., Marullo L., Alfano G., Pelaggi P., Talarico R., Tuccillo B., Irace L., Proietti F., Di Croce G., Di Lorenzo L., Zarrilli A., Bongini M., Ranise A., Aprile A., Fornengo C., Capogrosso V., Tranghese A., Golia B., Marziano A., Roncon L., Picariello C., Bagni E., Leci E., Gregorio G., Gatto F., Piemonte F., Gervasio F., Navazio A., Guerri E., Belmonte E., Marino F., Di Belardino N., Di Nuzzo M. R., Epifani M., Comolatti G., Conconi B., Benea D., Casu G., Merella P., Ammirati M. A., Corrado V. M., Spagnolo D., Caico S. I., Bonizzato S., Margheri M., Corrado L., Antonicelli R., Ferrigno C., Merlino A., Nassiacos D., Antonelli A., Marchese A., Villella A., Bechi S., Lo Bianco F., Bedogni F., Negro L., Donato L., Statile D., Cassin M., Fedele F., Granatelli A., Calcagno S., Politi A., Pani A., De Luca, L, Formigli, D, Meessen, J, Uguccioni, M, Cosentino, N, Paolillo, C, Di Lenarda, A, Colivicchi, F, Gabrielli, D, Gulizia, M, Scherillo, M, Maras, P, Ramani, F, Falcone, C, Passarelli, I, Mauri, S, Calabro, P, Bianchi, R, Di Palma, G, Mascia, F, Vetrano, A, Fusco, A, Proia, E, Aiello, A, Tomai, F, Licitra, R, Petrolini, A, Bosco, B, Magliari, F, Callerame, M, Mazzella, T, Lettica, G, Coco, G, Incao, F, Marinacci, L, D'Addario, S, Tartaglione, S, Ubaldi, S, Sanchez, F, Costa, P, Manca, G, Failla, M, Procaccini, V, Senni, M, Luminita, E, Bonomo, P, Mossa, C, Corda, S, Colavita, A, Trevisonno, G, Vizzari, G, Formaro, C, Nalin, I, De Rosa, F, Fontana, F, Fuscaldo, G, Passamonti, E, Bertella, E, Calvaruso, E, Varani, E, Tani, F, Cicchitelli, G, Paoloni, P, Marziali, A, Campo, G, Tebaldi, M, Biscaglia, S, Di Biase, M, Brunetti, N, Gallotta, A, Mattei, L, Marini, R, Balsemin, F, D'Urbano, M, Naio, R, Vicinelli, P, Arena, G, Mazzini, M, Gigli, N, Miserrafiti, B, Monopoli, A, Mortara, A, Delfino, P, Chioffi, M, Marino, P, Gravellone, M, Barbieri, L, Ledda, A, Geraci, G, Carmina, M, Raisaro, A, Di Giacomo, C, Somaschini, A, Fasano, M, Sannazzaro, M, Arcieri, R, Pantaleoni, M, Leuzzi, C, Gorlato, G, Greco, G, Chiera, A, Ammaturo, T, Malanchini, G, Del Corral, M, Tedesco, L, Pede, S, Urso, L, Piscione, F, Galasso, G, Provasoli, S, Fattore, L, Lucca, G, Cresti, A, Cardillo, A, Fera, M, Vennettilli, F, Gaudio, C, Paravati, V, Caldarola, P, Locuratolo, N, Verlato, R, De Conti, F, Turiano, G, Preti, G, Moretti, L, Silenzi, S, Colonna, G, Picciolo, A, Nicosia, A, Cascone, C, Di Sciascio, G, Mangiacapra, F, Russo, A, Mastroianno, S, Esposito, G, Cosmi, F, D'Orazio, S, Costantini, C, Lanari, A, De Rosa, P, Esposito, L, Bilato, C, Dalla Valle, C, Ceresa, M, Colombo, E, Pennisi, V, Casciola, G, Driussi, M, Bisceglia, T, Scalvini, S, Rivadossi, F, Volpe, M, Comito, F, Scorzoni, D, Grimoldi, P, Lagioia, R, Santoro, D, De Cesare, N, Comotti, T, Poli, A, Martina, P, Musolino, M, Multari, E, Bilardo, G, Scalchi, G, Olivieri, C, Caranci, F, Pavan, D, Ganci, G, Mariani, A, Falchetti, E, Lanzillo, T, Caccavale, A, Bongo, A, Rizzi, A, Favilli, R, Maffei, S, Mallardo, M, Fulgione, C, Bordin, F, Bonmassari, R, Battaia, E, Puzzo, A, Vianello, G, D'Arpino, A, Romei, M, Pajes, G, Petronzelli, S, Ghezzi, F, Brigido, S, Pignatelli, L, Brscic, E, Sori, P, Russo, M, Biancolillo, E, Ignone, G, De Giorgio, N, Campaniello, C, Ponticelli, P, Margonato, A, Gerosa, S, Cutaia, A, Casalicchio, C, Bartolomucci, F, Larosa, C, Spadafina, T, Putignano, A, Se Cristofaro, R, Bernardi, L, Sommariva, L, Celestini, A, Bertucci, C, Marchetti, M, Franceschini Grisolia, E, Ammendolea, C, Carini, M, Scipione, P, Politano, M, Rubino, G, Reina, C, Peccerillo, N, Paloscia, L, D'Alleva, A, Petacchi, R, Pignalosa, M, Lucchetti, D, Di Palma, F, La Mastra, R, Amico, A, De Filippis, M, Fontanella, B, Zanini, G, Casolo, G, Del Meglio, J, Parato, V, Genovesi, E, D'Alimonte, A, Miglioranza, A, Alessandri, N, Moscariello, F, Mauro, C, Sasso, A, Caso, P, Petrillo, C, Napoletano, C, Paparoni, S, Bernardo, V, Serdoz, R, Rotunno, R, Oppo, I, Aloisio, A, Aurelio, A, Licciardello, G, Cassaniti, L, Francese, G, Marcassa, C, Temporelli, P, Villani, R, Zorzoli, F, Mileto, F, De Vecchis, M, Scolozzi, D, Lupi, G, Caruso, D, Rebulla, E, La Fata, B, Anselmi, M, Girardi, P, Borruso, E, Ferrantelli, G, Sassone, B, Bressan, S, Capriolo, M, Pelissero, E, Piancastelli, M, Gobbi, M, Cocco, F, Bruno, M, Berti, S, Lo Surdo, G, Tanzi, P, De Rosa, R, Vilei, E, De Iaco, M, Grassi, G, Zanella, C, Marullo, L, Alfano, G, Pelaggi, P, Talarico, R, Tuccillo, B, Irace, L, Proietti, F, Di Croce, G, Di Lorenzo, L, Zarrilli, A, Bongini, M, Ranise, A, Aprile, A, Fornengo, C, Capogrosso, V, Tranghese, A, Golia, B, Marziano, A, Roncon, L, Picariello, C, Bagni, E, Leci, E, Gregorio, G, Gatto, F, Piemonte, F, Gervasio, F, Navazio, A, Guerri, E, Belmonte, E, Marino, F, Di Belardino, N, Di Nuzzo, M, Epifani, M, Comolatti, G, Conconi, B, Benea, D, Casu, G, Merella, P, Ammirati, M, Corrado, V, Spagnolo, D, Caico, S, Bonizzato, S, Margheri, M, Corrado, L, Antonicelli, R, Ferrigno, C, Merlino, A, Nassiacos, D, Antonelli, A, Marchese, A, Villella, A, Bechi, S, Lo Bianco, F, Bedogni, F, Negro, L, Donato, L, Statile, D, Cassin, M, Fedele, F, Granatelli, A, Calcagno, S, Politi, A, and Pani, A

Subjects
medicine.medical_specialty, animal structures, Population, Myocardial Infarction, Coronary artery disease, Rivaroxaban, Internal medicine, Epidemiology, medicine, Humans, Registries, Myocardial infarction, education, Stroke, education.field_of_study, Aspirin, business.industry, Health Policy, Incidence (epidemiology), medicine.disease, COMPASS trial, Cohort, Cardiology and Cardiovascular Medicine, business, START registry, Mace
Abstract

Aims Recently, the cardiovascular outcomes for people using anticoagulation strategies (COMPASS) trial demonstrated that dual therapy reduced cardiovascular outcomes compared with aspirin alone in patients with stable atherosclerotic disease. Methods and results We sought to assess the proportion of patients eligible for the COMPASS trial and to compare the epidemiology and outcome of these patients with those without COMPASS inclusion or with any exclusion criteria in a contemporary, nationwide cohort of patients with stable coronary artery disease. Among the 4068 patients with detailed information allowing evaluation of eligibility, 1416 (34.8%) did not fulfil the inclusion criteria (COMPASS-Not-Included), 841 (20.7%) had exclusion criteria (COMPASS-Excluded), and the remaining 1811 (44.5%) were classified as COMPASS-Like. At 1 year, the incidence of major adverse cardiovascular event (MACE), a composite of cardiovascular death, myocardial infarction, and stroke, was 0.9% in the COMPASS-Not-Included and 2.0% in the COMPASS-Like (P = 0.01), and 5.0% in the COMPASS-Excluded group (P Conclusion In a contemporary real-world cohort registry of stable coronary artery disease, most patients resulted as eligible for the COMPASS. These patients presented a considerable annual risk of MACE that consistently increases in the presence of multiple risk factors.

Published
2021

48. EURObservational Research Programme: the Chronic Ischaemic Cardiovascular Disease Registry: Pilot phase (CICD-PILOT)

Author

Komajda, Michel, Weidinger, Franz, Kerneis, Mathieu, Cosentino, Francesco, Cremonesi, Alberto, Ferrari, Roberto, Kownator, Serge, Steg, Philippe Gabriel, Tavazzi, Luigi, Valgimigli, Marco, Szwed, Hanna, Majda, Wojciech, Olivari, Zoran, Van Belle, Eric, Shlyakhto, Evgeny Vladimirovich, Mintale, Iveta, Slapikas, Rimvydas, Rittger, Harald, Mendes, Miguel, Tsioufis, Constantinos, Balanescu, Serban, Laroche, Cécile, Maggioni, Aldo Pietro, Komajda, Michel, Weidinger, Franz, Cosentino, Francesco, Cremonesi, Alberto, Ferrari, Roberto, Kownator, Serge, Maggioni, Aldo P., Steg, Gabriel, Tavazzi, Luigi, Valgimigli, Marco, Balanescu, Serban, Mendes, Miguel, Mintale, Iveta, Olivari, Zoran, Rittger, Harald, Shlyakhto, Evgeny V., Slapikas, Rimvydas, Szwed, Hanna, Van Belle, Éric, Laroche, Cécile, McNeill, Patti-Ann, Ferreira, Thierry, Vochelet, F., Tavildari, A., Silvestri, M., Maillard, L., Sevilla, J., Malaquin, D., Leborgne, L., Fournier, A., Jarry, G., Teiger, E., Marchant, B., Van Belle, E., Criquioche, A., Dupouy, P., Madiot, H., Lafitte, B., Belle, L., Cayla, G., Abouth-Benamara, S., Messas, E., Delarche, N., Bouvier, E., Couleru, J., Paparoni, F., Marchant, B., Bedossa, M., Lepage, Q., Le Bouquin, L., Auffret, V., Leurent, G., Boulmier, D., Le Breton, H., Vidal, C., Touet, M., Tron, C., Hemmerling, S., Flugel, P.-C., Beschorner, U., Noory, E., Strubin, J., Macharzina, R., Lindemann, C., Specht, T., Brantner, R., Zeller, T., Schwarzwalder, U., Hirschmann, S., Schonhardt, S., Slimack-Braun, S., Link, S., Hauk, M., Welslau, M., Henning, A., Menz, C., Buciuceanu, V., Rastan, A., Bschorr, R., Schmitt, C., Maas, C., Jacques, B., Bohme, T., Burgelin, K., Hoffmann, M., Pirzer, R., Brune, M., Braun, M., Stolte, D., Dietrich, A., Singh, A., Rittger, H., Schibgilla, V., Hopf, S., Fouridis, P., Fabiani, R., Jakob, A., Garlichs, C., Trautvetter, J., Schineis, N., Brugger, A., Bojanic, D., Matschke, C., Schmidt, A., Scheinert, D., Scheinert, S., Banning-Eichenseer, U., Stauffer, A., Straube, F., Hoffmann, E., Antoni, D., Rieber, J., Tomelden, J., Deichstetter, M., Landwehr, P., Reif, S., Kallikazaros, I., Tsioufis, C., Korkovili, M., Stamatelopoulos, K., Tsoumani, Z., Loizos, S., Kanakakis, I., Kampouridis, N., Simeonidis, D., Bougas, T., Chasapi, A., Alexopoulos, D., Xanthopoulou, I., Vogiatzi, X., Stavrou, K., Bampouri, T., Sicuro, M., Amato, G., Pisano, F., Casolati, D., Bare, C., Grotti, S., Angioli, P., Bolognese, L., Ducci, K., Porto, I., Falsini, G., Liisto, F., Manzi, R.C., Langiu, M., Lai, C., Lodolini, V., Biscaglia, S., Ferrari, R., Occhilupo, P., Tebaldi, M., Minarelli, M., Fileti, L., Campo, G., Sbarzaglia, P., Bonilla, N., Schiavina, G., dʼAlessandro, G., Borghesi, M., Cremonesi, A., Rota, I., Ghigliotti, G., Davi, F., Beccaria, F., Brunelli, C., Mussardo, M., Cisotta, F., Spagnolo, B., Liso, A., Dal Corso, L., Favretto, G., Borsatto, F., Benedetto, M., Cirrincione, G., Gandolfo, C., Caruso, M., Stabile, A., Lanteri, S., Riina, M., Lunetto, M.L., Vadala, G., Micari, A., Rossi, E., Griksteite, E., Cavallini, C., Longhi, S., Pasqualini, M., Negrelli, M., Pacchioni, E., Brunazzi, M.C., Marcomin, C., Neri, R., Cassin, M., Vendrametto, F., Macor, F., Nicolosi, G., Pavan, D., Piasentin, C., Roman-Pognuz, A., Taccheri, T., Calcagno, S., Pagliaro, M., Mancone, M., Fedele, F., Cinque, A., Armato, A., Tarducci, R., Della Bona, R., Brandini, R., Rossi, P., Fronticelli, M., Casavecchia, M., Olivari, Z., Calzolari, D., Daniotti, A., Balcere, K., Stirna, V., Libins, A., Zabunova, M., Silina, E., Ozola, G., Rancane, G., Babarskiene, R., Viezelis, M., Petrauskaite, J., Rumbinaite, E., Stankala, S., Juszczyk, Z., Karwowska Polecka, W., Oleksza, A., Bialek, P., Klimczuk, A., Poplawski, A., Aksiucik, A., Musial, W., Swiecki, P., Marcinkiewicz-Siemion, M., Ptaszynska-Kopczynska, K., Prokop, J., Kubica, J., Janiszewska, E., Kopczynska, A., Tarnawska, M., Gruchala, M., Pajkowski, M., Raczak, G., Wojtowicz, D., Strozyk, A., Miekus, P., Szyman, M., Glaza, M., Roszko-Grycner, E., Szpajer, M., Wroblewska, M., Zadrozny, J., Muller, H., Puzio, E., Lesinski, D., Borowski, B., Kowalska, A., Wojtyniak, I., Krzewinska, J., Borej, G., Czaja, P., Janion, M., Zandecki, L., Kuczerowska, R., Bogacki, P., Kafara, M., Rola, A., Podolec, P., Waligora, M., Brozda, M., Skrzynska, M., Glowa, B., Gawor, Z., Dejak, P., Brylka, A., Banasiak, M., Simiera, M., Krecki, R., Ojrzanowski, M., Jankowski, L., Kupczynska, K., Kasprzak, J.D., Zapolski, T., Zarczuk, R., Lukasik, D., Wysokinski, A., Zalewska-Nowak, G., Tarnolicki, M., Major, M., Gorny, J., Krzyzanowski, W., Muzyk-Osikowicz, M., Boltryk, K., Grajek, S., Maczynski, M., Lesiak, M., Komosa, A., Drewnicki, A., Wolniewicz, L., Komorowska, E., Gmyrek, N., Kowalik, M., Kostka, M., Kaminski, L., Mikolowicz-Mosiadz, A., Mazur, R., Kosztowniak, M., Pajaczkowski, K., Duda, K., Kosno-Zak, J., Dworak-Podlewska, E., Burchard, E., Wrzosek, B., Gurba, S., Wozniak, P., Dabek, M., Kuzniar, J., Lyczywek, M., Szubielski, M., Gajewski, M., Wasiak, D., Oscik-Lukasiewicz, M., Kawka-Urbanek, T., Diks, F., Przywoska-Para, B., Drazkowicz-Gozdzik, B., Kornacewicz-Jach, Z., Kula, L., Goracy, J., Chlasta, J., Tomaniak, M., Opolski, G., Serafin, A., Pietrasik, A., Kosek, M., Jastrzebski, J., Witkowski, A., Pruszczyk, P., Roik, M., Kostrubiec, M., Irzyk, K., Wretowski, D., Labyk, A., Budaj, A., Maciejewski, P., Szwed, H., Majda, W., Chojecka, M., Mosur, M., Gajer-Blaszczyk, K., Bociaga, Z., Loboz-Rudnicka, M., Loboz-Grudzien, K., Jaroch, J., Rzyczkowska, B., Chelstowski, W., Lewandowska, A., Darocha, A., Skowron, W., Polonski, L., Maciol-Skurk, K., Madeira, S., Mendes, M., Brito, J., Santos, M., Leite, L., Vicente, J., Calisto, J., Faria, H., Jorge, E., Mendes, A., Santos, R., Pinto, P., Guedes, H., Placido, R., Correia, M.J., Cabrita, I., Rodrigues, C., Nunes Diogo, A., Magalhaes, A., Canas da Silva, A., Selas, M., Portugal, G., Viveiros Monteiro, A., Timoteo, A.T., Ribeiro, M., Espregueira Mendes, D., Rodrigues, R., Lopes, R., Ribeiro, V., Melao, F., Magalhaes, D., Silva, J., Ribeiro, V. Gama, Braga, P., Goncalves, M., de Morais, G. Pires, Melica, B., Rodrigues, A., Santos, L., Cojocaru, L., Mazilu, L., Suceveanu, A.I., Rusali, A., Parepa, I.R., Maxim, R., Matei, L., Ioanovici, S., Buzas, R., Mihaela Iuliana, M., Susan, M., Ionita, M., Coceala, L., Suceava, I., Ciobotaru, G., Lighezan, D., Nicolescu, C., Mukhametgatova, D., Baleeva, L., Galyavich, A., Gratsiansky, N.A., Erlikh, A., Kondratenko, V., Libis, R., Vezikova, N., Skopets, I., Marusenko, I., Lapshin, K., Yakovlev, A., Lokhovinina, N., Alugishvili, M., Panov, A., Abesadze, I., Salakhova, J., Kondrateva, I., and Duplyakov, D.

Published
2016
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50. The Italian arm of the PREPARE study: an international project to evaluate and license a maternal vaccine against group B streptococcus

Author

Berardi A., Cassetti T., Creti R., Vocale C., Ambretti S., Sarti M., Facchinetti F., Cose S., van Bijlsma M., van De Beek D., Poyart C., French N., Nielsen M., Musoke P., Davies H., Ovale S., Lugli L., Capretti M. G., Lanari M., Dondi A., Ciccia M., Francavilla R., Lanzoni A., Baroni L., Fornaciari S., Carretto E., Alessandrini C., Lucia G., Perrone S., Calderaro A., Bacchini P., Giugno C., Rota C., Pagano R., Guidi B., Biasucci G., Benenati B., Schiavo R., Piccinini G., Pulvirenti R., Rizzo V., Ancora G., China C., Papa I., Viola L., Pedna M. F., Bua J., Travan L., Busetti M., Santori D., Merazzi D., Papa A., Laura L., Auriti C., Bernaschi P., Vento G., Giordano L., Spanu T., Haass C., Margiotta M. C., Nardella G., De Nittis R., Laforgia N., Loprieno S., Giuseppe L., Moramarco A. M., Tzialla C., Fasolato V., Orlandini S., Decembrino L., Del Campo G., Maiocchi A., Cuttano A., Tuoni C., Barnini S., Carnielli V., Perrone B., Orecchioni F., Visintini F., Arzese A., Heath P., Le Doare K., Neurology, Amsterdam Neuroscience - Neuroinfection & -inflammation, AII - Infectious diseases, Berardi A., Cassetti T., Creti R., Vocale C., Ambretti S., Sarti M., Facchinetti F., Cose S., van Bijlsma M., van De Beek D., Poyart C., French N., Nielsen M., Musoke P., Davies H., Ovale S., Lugli L., Capretti M.G., Lanari M., Dondi A., Ciccia M., Francavilla R., Lanzoni A., Baroni L., Fornaciari S., Carretto E., Alessandrini C., Lucia G., Perrone S., Calderaro A., Bacchini P., Giugno C., Rota C., Pagano R., Guidi B., Biasucci G., Benenati B., Schiavo R., Piccinini G., Pulvirenti R., Rizzo V., Ancora G., China C., Papa I., Viola L., Pedna M.F., Bua J., Travan L., Busetti M., Santori D., Merazzi D., Papa A., Laura L., Auriti C., Bernaschi P., Vento G., Giordano L., Spanu T., Haass C., Margiotta M.C., Nardella G., De Nittis R., Laforgia N., Loprieno S., Giuseppe L., Moramarco A.M., Tzialla C., Fasolato V., Orlandini S., Decembrino L., Del Campo G., Maiocchi A., Cuttano A., Tuoni C., Barnini S., Carnielli V., Perrone B., Orecchioni F., Visintini F., Arzese A., Heath P., and Le Doare K.

Subjects
0301 basic medicine, Pediatrics, medicine.medical_specialty, Group B streptococcus, Sepsi, International Cooperation, 030106 microbiology, Disease, Abortion, Group B, Streptococcus agalactiae, Sepsis, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Streptococcal Infections, medicine, Humans, Meningitis, 030212 general & internal medicine, Newborn, Prevention, Vaccine, Pregnancy Complications, Infectious, Antibiotic prophylaxis, reproductive and urinary physiology, Group B streptococcu, business.industry, Streptococcal Vaccines, Infant, Newborn, lcsh:RJ1-570, lcsh:Pediatrics, Antibiotic Prophylaxis, medicine.disease, Infectious Disease Transmission, Vertical, Meningiti, Pneumonia, Italy, Immunization, Commentary, Female, business
Abstract

Background Group B streptococcus (GBS) is a leading cause of sepsis, pneumonia and meningitis in infants, with long term neurodevelopmental sequelae. GBS may be associated with poor pregnancy outcomes, including spontaneous abortion, stillbirth and preterm birth. Intrapartum antibiotic prophylaxis (IAP) is currently the only way to prevent early-onset disease (presenting at 0 to 6 days of life), although it has no impact on the disease presenting over 6 days of life and its implementation is challenging in resource poor countries. A maternal vaccine against GBS could reduce all GBS manifestations as well as improve pregnancy outcomes, even in low-income countries. Main body The term “PREPARE” designates an international project aimed at developing a maternal vaccination platform to test vaccines against neonatal GBS infections by maternal immunization. It is a non-profit, multi-center, interventional and experimental study (promoted by the St George University of London. [UK]) with the aim of developing a maternal vaccination platform, determining pregnancy outcomes, and defining the extent of GBS infections in children and mothers in Africa. PREPARE also aims to estimate the protective serocorrelates against the main GBS serotypes that cause diseases in Europe and Africa and to conduct two trials on candidate GBS vaccines. PREPARE consists of 6 work packages. In four European countries (Italy, UK, Netherlands, France) the recruitment of cases and controls will start in 2020 and will end in 2022. The Italian PREPARE network includes 41 centers. The Italian network aims to collect: GBS isolates from infants with invasive disease, maternal and neonatal sera (cases); cord sera and GBS strains from colonized mothers whose infants do not develop GBS infection (controls). Short conclusion PREPARE will contribute information on protective serocorrelates against the main GBS serotypes that cause diseases in Europe and Africa. The vaccine that will be tested by the PREPARE study could be an effective strategy to prevent GBS disease.

Published
2020

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