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2. Correction: Characterising illness stages and recovery trajectories of eating disorders in young people via remote measurement technology (STORY): a multi-centre prospective cohort study protocol

Author

Kuehne, Carina, Phillips, Matthew D., Moody, Sarah, Bryson, Callum, Campbell, Iain C., Conde, Pauline, Cummins, Nicholas, Desrivières, Sylvane, Dineley, Judith, Dobson, Richard, Douglas, Daire, Folarin, Amos, Gallop, Lucy, Hemmings, Amelia, İnce, Başak, Mason, Luke, Rashid, Zulqarnain, Bromell, Alice, Sims, Christopher, Allen, Karina, Bailie, Chantal, Bains, Parveen, Basher, Mike, Battisti, Francesca, Baudinet, Julian, Bristow, Katherine, Dawson, Nicola, Dodd, Lizzie, Frater, Victoria, Freudenthal, Robert, Gripton, Beth, Kan, Carol, Khor, Joel W. T., Kotze, Nicus, Laverack, Stuart, Martin, Lee, Maxwell, Sarah, McDonald, Sarah, McKnight, Delysia, McKay, Ruairidh, Merrin, Jessica, Nash, Mel, Nicholls, Dasha, Palmer, Shirlie, Pearce, Samantha, Roberts, Catherine, Serpell, Lucy, Severs, Emilia, Simic, Mima, Staton, Amelia, Westaway, Sian, Sharpe, Helen, and Schmidt, Ulrike

Published
2024
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3. Characterising illness stages and recovery trajectories of eating disorders in young people via remote measurement technology (STORY): a multi-centre prospective cohort study protocol

Author

Kuehne, Carina, Phillips, Matthew D., Moody, Sarah, Bryson, Callum, Campbell, Iain C., Conde, Pauline, Cummins, Nicholas, Desrivières, Sylvane, Dineley, Judith, Dobson, Richard, Douglas, Daire, Folarin, Amos, Gallop, Lucy, Hemmings, Amelia, İnce, Başak, Mason, Luke, Rashid, Zulqarnain, Bromell, Alice, Sims, Christopher, Allen, Karina, Bailie, Chantal, Bains, Parveen, Basher, Mike, Battisti, Francesca, Baudinet, Julian, Bristow, Katherine, Dawson, Nicola, Dodd, Lizzie, Frater, Victoria, Freudenthal, Robert, Gripton, Beth, Kan, Carol, Khor, Joel W. T., Kotze, Nicus, Laverack, Stuart, Martin, Lee, Maxwell, Sarah, McDonald, Sarah, McKnight, Delysia, McKay, Ruairidh, Merrin, Jessica, Nash, Mel, Nicholls, Dasha, Palmer, Shirlie, Pearce, Samantha, Roberts, Catherine, Serpell, Lucy, Severs, Emilia, Simic, Mima, Staton, Amelia, Westaway, Sian, Sharpe, Helen, and Schmidt, Ulrike

Published
2024
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6. Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals With Anorexia Nervosa: A Coordinated Analysis by the ENIGMA Eating Disorders Working Group

Author

Walton, Esther, Bernardoni, Fabio, Batury, Victoria-Luise, Bahnsen, Klaas, Larivière, Sara, Abbate-Daga, Giovanni, Andres-Perpiña, Susana, Bang, Lasse, Bischoff-Grethe, Amanda, Brooks, Samantha J., Campbell, Iain C., Cascino, Giammarco, Castro-Fornieles, Josefina, Collantoni, Enrico, D’Agata, Federico, Dahmen, Brigitte, Danner, Unna N., Favaro, Angela, Feusner, Jamie D., Frank, Guido K.W., Friederich, Hans-Christoph, Graner, John L., Herpertz-Dahlmann, Beate, Hess, Andreas, Horndasch, Stefanie, Kaplan, Allan S., Kaufmann, Lisa-Katrin, Kaye, Walter H., Khalsa, Sahib S., LaBar, Kevin S., Lavagnino, Luca, Lazaro, Luisa, Manara, Renzo, Miles, Amy E., Milos, Gabriella F., Monteleone, Alessio Maria, Monteleone, Palmiero, Mwangi, Benson, O’Daly, Owen, Pariente, Jose, Roesch, Julie, Schmidt, Ulrike H., Seitz, Jochen, Shott, Megan E., Simon, Joe J., Smeets, Paul A.M., Tamnes, Christian K., Tenconi, Elena, Thomopoulos, Sophia I., van Elburg, Annemarie A., Voineskos, Aristotle N., von Polier, Georg G., Wierenga, Christina E., Zucker, Nancy L., Jahanshad, Neda, King, Joseph A., Thompson, Paul M., Berner, Laura A., and Ehrlich, Stefan

Published
2022
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7. Exploring the relationship between proactive inhibition and restrictive eating behaviours in severe and enduring anorexia nervosa (SE-AN).

Author

Bartholdy, Savani, Dalton, Bethan, Rennalls, Samantha J., Kekic, Maria, McClelland, Jessica, Campbell, Iain C., O'Daly, Owen G., and Schmidt, Ulrike

Subjects
DIETARY patterns, RESPONSE inhibition, FOOD habits, COGNITIVE psychology, ANOREXIA nervosa
Abstract

Background: There is a need for improved understanding of why 20–30% of individuals with anorexia nervosa (AN) develop a severe and enduring form of illness (SE-AN). Previously, we reported differences in proactive inhibition (a pre-emptive slowing of responses) in individuals with AN compared to healthy controls (after controlling for intolerance of uncertainty). The present study is a preliminary exploration of proactive inhibition in which we compared women with SE-AN with healthy comparison (HC) women and explored its association with restrictive/avoidant eating behaviours. Methods: Thirty-four women with SE-AN (defined by >3 years of illness and a previous unsuccessful course of eating disorder treatment) and 30 HCs completed (a) a cued reaction time task, to assess proactive inhibition, and (b) questionnaires assessing restrictive/avoidant eating behaviours and intolerance of uncertainty. Results: Both SE-AN and HC participants showed slower reaction times under conditions of uncertainty, indicating proactive inhibition in both groups. There was a main effect of group, with SE-AN participants showing significantly slower reaction times compared to HC. There was no interaction between group and condition, suggesting that individuals with SE-AN did not differ in proactive inhibition compared to HCs. However, post-hoc analysis between-group tests for each trial type revealed that group differences were only present under conditions of uncertainty. Proactive inhibition was not significantly associated with self-reported restrictive/avoidant eating behaviours, including when taking intolerance of uncertainty into consideration. Conclusions: It is unlikely that proactive inhibition contributes to avoidant and restrictive eating behaviours seen in SE-AN. Our findings suggest that the SE-AN group are relatively more cautious when responding under conditions of uncertainty. Longitudinal studies and between-group comparisons of individuals across different stages of illness will be required to elucidate the way in which proactive inhibition is specifically implicated in SE-AN, rather than in AN more generally. Plain English Summary: Proactive inhibition refers to the pre-emptive slowing of responses. We assessed whether 34 women with severe and enduring anorexia nervosa (defined by greater than 3 years of illness and a previous unsuccessful course of treatment) differed from 30 healthy comparison women in proactive inhibition. We also explored if proactive inhibition was related to restrictive eating behaviours. All participants completed a cued reaction time task to assess proactive inhibition and questionnaires assessing restrictive/avoidant eating behaviours and intolerance of uncertainty. All participants showed proactive inhibition, i.e., slower reaction times under conditions of uncertainty. Participants with severe and enduring anorexia nervosa showed significantly slower reaction times compared to healthy comparison women. Proactive inhibition was not significantly associated with self-reported restrictive/avoidant eating behaviours. Our findings suggest that compared to the healthy comparison group of women, the severe and enduring anorexia nervosa group are more cautious when responding, specifically in the context of uncertainty. It is unlikely that proactive inhibition contributes to avoidant and restrictive eating behaviours in severe and enduring anorexia nervosa. [ABSTRACT FROM AUTHOR]

Published
2025
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8. The Status of Neuromodulation Trials in Eating Disorders

Author

Schmidt, Ulrike and Campbell, Iain C.

Subjects
Psychotherapy, Anorexia nervosa -- Care and treatment, Attentional bias, Health, Psychology and mental health
Abstract

The classical eating disorders (EDs), anorexia nervosa (AN) and bulimia nervosa (BN), and their newer DSM-5 cousins-binge-eating disorder (BED), other specified feeding and eating disorder, and avoidant restrictive food intake [...]

Published
2023

18. Neural Correlates of Failed Inhibitory Control as an Early Marker of Disordered Eating in Adolescents

Author

Rapp, Michael, Artiges, Eric, Schneider, Sophia, Bach, Christine, Paus, Tomas, Barbot, Alexis, Gareth Barker, Bokde, Arun, Vetter, Nora, Büchel, Christian, Cattrell, Anna, Constant, Patrick, Gowland, Penny, Crombag, Hans, Czech, Katharina, Dalley, Jeffrey, Decideur, Benjamin, Spranger, Tade, Ripley, Tamzin, Heym, Nadja, Flor, Herta, Sommer, Wolfgang, Fuchs, Birgit, Gallinat, Jürgen, Spanagel, Rainer, Kaviani, Mehri, Heinrichs, Bert, Andreas Heinz, Subramaniam, Naresh, Jia, Tianye, Ihlenfeld, Albrecht, Ireland, James, Ittermann, Bernd, Conrod, Patricia, Banaschewski, Tobias, Jones, Jennifer, Klaassen, Arno, Lalanne, Christophe, Lanzerath, Dirk, Lawrence, Claire, Lemaitre, Hervé, Desrivieres, Sylvane, Mallik, Catherine, Karl Mann, Mar, Adam, Martinez-Medina, Lourdes, Jean-Luc Martinot, Mennigen, Eva, Mesquita de Carvahlo, Fabiana, Schwartz, Yannick, Bruehl, Ruediger, Müller, Kathrin, Nees, Frauke, Nymberg, Charlotte, Lathrop, Mark, Trevor Robbins, Pausova, Zdenka, Jani Pentilla, Biondo, Francesca, Jean-Baptiste Poline, Hohmann, Sarah, Poustka, Luise, Millenet, Sabina, Michael Smolka, Fröhner, Juliane, Struve, Maren, Steve Williams, Hübner, Thomas, Bromberg, Uli, Aydin, Semiha, Rogers, John, Romanowski, Alexander, Schmäl, Christine, Schmidt, Dirk, Ripke, Stephan, Arroyo, Mercedes, Schubert, Florian, Pena-Oliver, Yolanda, Fauth-Bühler, Mira, Mignon, Xavier, Whelan, Robert, Speiser, Claudia, Fadai, Tahmine, Dai Stephens, Ströhle, Andreas, Paillere, Marie-Laure, Strache, Nicole, Theobald, David, Jurk, Sarah, Vulser, Helene, Miranda, Ruben, Yacubian, Juliana, Frouin, Vincent, Genauck, Alexander, Parchetka, Caroline, Gemmeke, Isabel, Kruschwitz, Johann, Weiß, Katharina, Walter, Henrik, Feng, Jianfeng, Papadopoulos, Dimitri, Filippi, Irina, Ing, Alex, Ruggeri, Barbara, Xu, Bing, Macare, Christine, Chu, Congying, Hanratty, Eanna, Burke Quinlan, Erin, Robert, Gabriel, Schumann, Gunter, Yu, Tao, Ziesch, Veronika, Stedman, Alicia, Bartholdy, Savani, O’Daly, Owen G., Campbell, Iain C., Barker, Gareth, Bokde, Arun L.W., Quinlan, Erin Burke, Desrivières, Sylvane, Garavan, Hugh, Heinz, Andreas, Martinot, Jean-Luc, Paillère Martinot, Marie-Laure, Orfanos, Dimitri Papadopoulos, Fröhner, Juliane H., Smolka, Michael N., and Schmidt, Ulrike

Published
2019
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20. A randomised controlled feasibility trial of intermittent theta burst stimulation with an open longer‐term follow‐up for young people with persistent anorexia nervosa (RaISE): Study protocol

Author

Hemmings, Amelia, primary, Gallop, Lucy, additional, İnce, Başak, additional, Cutinha, Darren, additional, Kan, Carol, additional, Simic, Mima, additional, Zadeh, Ewa, additional, Malvisi, Isabella, additional, McKenzie, Katie, additional, Zocek, Lucy, additional, Sharpe, Helen, additional, O’Daly, Owen, additional, Campbell, Iain C., additional, and Schmidt, Ulrike, additional

Published
2024
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29. EDIFY (Eating Disorders: Delineating Illness and Recovery Trajectories to Inform Personalised Prevention and Early Intervention in Young People):project outline

Author

Hemmings, Amelia, Sharpe, Helen, Allen, Karina, Bartel, Heike, Campbell, Iain C., Desrivières, Sylvane, Dobson, Richard J. B., Folarin, Amos A., French, Tara, Kelly, Jonathan, Micali, Nadia, Raman, Sneha, Treasure, Janet, Abbas, Ruby, Heslop, Beck, Street, Tallulah, Schmidt, Ulrike, Hemmings, Amelia, Sharpe, Helen, Allen, Karina, Bartel, Heike, Campbell, Iain C., Desrivières, Sylvane, Dobson, Richard J. B., Folarin, Amos A., French, Tara, Kelly, Jonathan, Micali, Nadia, Raman, Sneha, Treasure, Janet, Abbas, Ruby, Heslop, Beck, Street, Tallulah, and Schmidt, Ulrike

Abstract

EDIFY (Eating Disorders: Delineating Illness and Recovery Trajectories to Inform Personalised Prevention and Early Intervention in Young People) is an ambitious research project aiming to revolutionise how eating disorders are perceived, prevented and treated. Six integrated workstreams will address key questions, including: What are young people's experiences of eating disorders and recovery? What are the unique and shared risk factors in different groups? What helps or hinders recovery? How do the brain and behaviour change from early- to later-stage illness? How can we intervene earlier, quicker and in a more personalised way? This 4-year project, involving over 1000 participants, integrates arts, design and humanities with advanced neurobiological, psychosocial and bioinformatics approaches. Young people with lived experience of eating disorders are at the heart of EDIFY, serving as advisors and co-producers throughout. Ultimately, this work will expand public and professional perceptions of eating disorders, uplift under-represented voices and stimulate much-needed advances in policy and practice.

Published
2023

30. EDIFY (Eating Disorders: Delineating Illness and Recovery Trajectories to Inform Personalised Prevention and Early Intervention in Young People): project outline.

Author

Hemmings, Amelia, Sharpe, Helen, Allen, Karina, Bartel, Heike, Campbell, Iain C., Desrivières, Sylvane, Dobson, Richard J. B., Folarin, Amos A., French, Tara, Kelly, Jonathan, Micali, Nadia, Raman, Sneha, Treasure, Janet, Abbas, Ruby, Heslop, Beck, Street, Tallulah, and Schmidt, Ulrike

Subjects
EATING disorders, NEUROBIOLOGY
Abstract

EDIFY (Eating Disorders: Delineating Illness and Recovery Trajectories to Inform Personalised Prevention and Early Intervention in Young People) is an ambitious research project aiming to revolutionise how eating disorders are perceived, prevented and treated. Six integrated workstreams will address key questions, including: What are young people's experiences of eating disorders and recovery? What are the unique and shared risk factors in different groups? What helps or hinders recovery? How do the brain and behaviour change from early- to later-stage illness? How can we intervene earlier, quicker and in a more personalised way? This 4-year project, involving over 1000 participants, integrates arts, design and humanities with advanced neurobiological, psychosocial and bioinformatics approaches. Young people with lived experience of eating disorders are at the heart of EDIFY, serving as advisors and co-producers throughout. Ultimately, this work will expand public and professional perceptions of eating disorders, uplift under-represented voices and stimulate much-needed advances in policy and practice. [ABSTRACT FROM AUTHOR]

Published
2023
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32. Identifying disordered eating behaviours in adolescents: how do parent and adolescent reports differ by sex and age?

Author

Bartholdy, Savani, Allen, Karina, Hodsoll, John, O’Daly, Owen G., Campbell, Iain C., Banaschewski, Tobias, Bokde, Arun L. W., Bromberg, Uli, Büchel, Christian, Quinlan, Erin Burke, Conrod, Patricia J., Desrivières, Sylvane, Flor, Herta, Frouin, Vincent, Gallinat, Jürgen, Garavan, Hugh, Heinz, Andreas, Ittermann, Bernd, Martinot, Jean-Luc, Artiges, Eric, Nees, Frauke, Orfanos, Dimitri Papadopoulos, Paus, Tomáš, Poustka, Luise, Smolka, Michael N., Mennigen, Eva, Walter, Henrik, Whelan, Robert, Schumann, Gunter, and Schmidt, Ulrike

Published
2017
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34. EDIFY (Eating Disorders: Delineating Illness and Recovery Trajectories to Inform Personalised Prevention and Early Intervention in Young People): project outline

Author

Hemmings, Amelia, primary, Sharpe, Helen, additional, Allen, Karina, additional, Bartel, Heike, additional, Campbell, Iain C., additional, Desrivières, Sylvane, additional, Dobson, Richard J.B., additional, Folarin, Amos A., additional, French, Tara, additional, Kelly, Jonathan, additional, Micali, Nadia, additional, Raman, Sneha, additional, Treasure, Janet, additional, Abbas, Ruby, additional, Heslop, Beck, additional, Street, Tallulah, additional, and Schmidt, Ulrike, additional

Published
2022
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46. ‘My dad was like “it's your brain, what are you doing?”’: Participant experiences of repetitive transcranial magnetic stimulation treatment in severe enduring anorexia nervosa

Author

Dalton, Bethan, primary, Austin, Amelia, additional, Ching, Brian C. F., additional, Potterton, Rachel, additional, McClelland, Jessica, additional, Bartholdy, Savani, additional, Kekic, Maria, additional, Campbell, Iain C., additional, and Schmidt, Ulrike, additional

Published
2022
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