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Introduction: Stroke can significantly limit functionality, a fact often not correlated with the neurological deficit itself. The psychiatric complications have been identified as key factors in post-stroke. Depression has shown to be the most common complication and the one associated with a worse prognosis. There is still uncertainty as to its etiology and risk factors. In the most recent systematic review, some factors are recognized: stroke severity, the degree of disability and cognitive impairment. Establishment of other factors wasn't possible due to methodological issues. Thus, it is urgent to define new factors that facilitate a timely diagnosis, which may lessen the negative effects on the rehabilitation process., Objectives: To determine the incidence of post-stroke depression (PSD) and to study variables described in the literature as possible predictors of PSD: sex, age, type of stroke, laterality, vascular territory and presence of aphasia. The study of the type of aphasia was defined as secondary endpoint., Methods: Retrospective longitudinal study involving all patients admitted to a PMR ward, with the diagnosis of stroke de novo, between 1/1/2009 and 31/12/2009. Demographic and clinical data was collected from 74 patients' files., Exclusion Criteria: 'previous stroke', 'prior psychiatric illness with mood disturbance' and 'antidepressant medication at the time of stroke'. SPSS 11.5 was used for statistical analysis., Results: The incidence of PSD was 44.6%. Amongst possible predictor factors tested, only the presence of aphasia showed a significant association with depression (p = 0.02). There was no relation with the type of aphasia. The other predictors tested showed no statistically significant correlation. There seems to be a relationship between male sex and the PSD (p = 0.07), which did not reach significance with this sample size (n)., Conclusions: This study establishes aphasia as a predictive factor of PSD and excludes the remaining variables. The high incidence of PSD in this particular population agrees with the existing studies, but a different study is needed to justify the value found. Further studies are needed, not only to increase knowledge of risk factors for PSD, as to improve the outcomes of rehabilitation programs.

Introduction: Diabetes Mellitus is the leading cause of lower limb amputation, representing a significant economic cost for health services. The development of diabetic ulcers is a main risk factor for amputations, which have a high mortality rate at five years. The ischemia caused by macrovascular disease is a key pathophysiological factor in the development of ischemic ulcers. Existing treatments are prolonged and associated with high rates of failure and relapse, requiring the combination of multiple therapeutic modalities. Lowlevel laser therapy has been used as an adjuvant therapy for diabetic foot ulcers, since the 1960's, due to its hypothetical stimulating effects over microcirculation and tissue repair., Material and Methods: Identification of published scientific studies through a literature search on PubMed, The Cochrane Library and Cochrane Controlled Trials Register., Discussion and Conclusions: Existing evidence is favourable for in vitro cell models, but conflicting in animal models and human populations. There is significant methodological heterogeneity, which may be responsible for discordant results. Guidelines are proposed for future studies in this area, including the detailed characterization of ulcers and the parameters of laser treatment. Well-controlled studies, randomized and double-blind are needed. Accordingly to the primum non nocere, laser therapy can and should be used as adjunctive therapy in the treatment of diabetic foot, because it isn't invasive, has low costs and is a fast therapy without significant adverse effects.