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243 results on '"Calvin, Andrew D."'

11. Life-Threatening Aortic Dissection during Pregnancy: A Case Report of Undiagnosed FBN1- Related Marfan Syndrome at 39 Weeks Gestation.

Author

Gurrieri, Carmelina, Manske, Westley T., Williams, Carla, Wildenberg, Joseph C., Keppers, Rachel J., Tallarita, Tiziano, Saran, Nishant, and Calvin, Andrew D.

Subjects
AORTIC dissection, ASCENDING aorta dissection, MARFAN syndrome, SYMPTOMS, PREGNANCY, INTENSIVE care units
Abstract

Background: Inherited deficiencies in the FBN1 gene, which encodes fibrillin-1, result in Marfan syndrome, an autosomal dominant connective tissue disorder that is associated with aortic root dilatation and predisposes to aortic dissection. This report is of a 37-year-old woman presenting at 39 weeks of pregnancy with acute thoracic aortic dissection due to previously undiagnosed FBN1-related Marfan syndrome. This case report aims to illustrate the challenges in the diagnosis and in the peri-operative management of acute aortic dissection during pregnancy. Case Report: A healthy 37-year-old woman at 39 weeks of gestation presented to our hospital with dyspnea and chest pain. Initial evaluation for pulmonary embolism with chest computed tomography was unrevealing. The patient was admitted to the intensive care unit for further management. Overnight, her clinical conditions deteriorated, and a transthoracic echocardiography was obtained, demonstrating an acute ascending aortic dissection. She emergently underwent a successful combined cesarean section and ascending aortic dissection repair, with no immediate complications. On postoperative day 4 she developed cardiac tamponade, for which she underwent emergent mediastinal exploration. She was discharged home on postoperative day 10. A month later she completed genetic testing, which revealed a pathogenic mutation in the FBN1 gene, consistent with a molecular diagnosis of Marfan syndrome. Conclusions: This report has shown that FBN1-related Marfan’s syndrome has a variable clinical presentation that can include life-threatening aortic dissection during pregnancy. Successful diagnosis and management of these patients is challenging and requires multidisciplinary expertise, including confirmation of the diagnosis by a clinical geneticist. [ABSTRACT FROM AUTHOR]

Published
2023
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33. 69-year-old woman with rapid heartbeat

Author

Calvin, Andrew D., Geske, Jeffrey B., and Bell, Malcolm R.

Subjects
Company business management, Myocarditis -- Diagnosis, Myocarditis -- Case studies, Myocarditis -- Prognosis, Myocarditis -- Care and treatment, Tachycardia -- Evaluation, Tachycardia -- Care and treatment, Emergency medical services -- Management
Abstract

A 69-year-old woman was transferred to Saint Marys Hospital for evaluation and treatment of a rapid heart-beat. Emergency medical services (EMS) had been called to her home because she was [...]

Published
2008

34. 37-year-old man with painful foot

Author

Geske, Jeffrey B., Calvin, Andrew D., and McDonald, Furman S.

Subjects
Thromboangiitis obliterans -- Diagnosis, Thromboangiitis obliterans -- Development and progression, Thromboangiitis obliterans -- Case studies, Foot diseases -- Diagnosis, Foot diseases -- Development and progression, Foot diseases -- Case studies, Smoking -- Health aspects
Abstract

A 37-year-old Asian man was admitted to a general medicine service at Saint Marys Hospital, a Mayo Clinic-affiliated hospital in Rochester, MN, with a painful foot. He had a 10-week [...]

Published
2008

47. Erratum. Aspirin for the Primary Prevention of Cardiovascular Events. A Systematic Review and Meta-Analysis Comparing Patients With and Without Diabetes. Diabetes Care 2009;32:2300–2306

Author

Calvin, Andrew D., primary, Aggarwal, Niti R., additional, Murad, Mohammad Hassan, additional, Shi, Qian, additional, Elamin, Mohamed B., additional, Geske, Jeffrey B., additional, Fernandez-Balsells, M. Merce, additional, Albuquerque, Felipe N., additional, Lampropulos, Julianna F., additional, Erwin, Patricia J., additional, Smith, Steven A., additional, and Montori, Victor M., additional

Published
2018
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