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This case series describes a possible link between perforation during gastrointestinal tract (GIT) endoscopy in cats and a specific underlying condition. GIT endoscopy is commonly performed in cats, with a total of 254 endoscopies performed at a UK referral centre from 1 January 2015 to 31 December 2019. During this period, three cases were reported to have GIT perforation in conjunction with the procedure. All three cases described were diagnosed with alimentary lymphoma of varying location and histological grade. One case suffered colonic perforation and was euthanased, while the other two underwent exploratory coeliotomy. Both surgeries were successful. Of the cats that underwent surgery, one was diagnosed with lymphoplasmocytic inflammation at the perforation site and low‐grade/small cell lymphoma distally, and subsequently treated with prednisolone and chlorambucil, while the other was diagnosed with intermediate‐grade lymphoma at the perforation site, and the owners elected for euthanasia upon diagnosis. [ABSTRACT FROM AUTHOR]

Objectives: The primary goals of this retrospective study were to describe a population of dogs with portal hypertension secondary to liver disease, and to assess whether prognosis could be inferred from historical, clinical, and clinicopathological data., Animals and Procedures: Dogs (N = 76) diagnosed with intrahepatic portal hypertension between 2011 and 2020 were included; dogs with known congenital hepatic anomalies were excluded. Effect on survival was assessed using univariable and multivariable Cox proportional hazards models for historical, clinical, and clinicopathological variables., Results: Dogs survived for a median of 14 d (range: 0 to 2028 d), with 31.6% being euthanized within 2 d of diagnosis and 23.7% surviving longer than 2 mo. Presence of jaundice and duration of clinical signs, expressed in days, were significantly associated with outcome in the univariable analysis (HR = 1.846, 95% CI: 1.094 to 3.117, P = 0.02; HR = 0.995, 95% CI: 0.990 to 1.000, P = 0.033, respectively). However, only presence of jaundice was significantly associated with increased hazard of death in the multivariable analysis., Conclusion: Results of this study show that portal hypertension is associated with a poor prognosis; however, some dogs can show prolonged survival., Clinical Relevance: Clinical data can guide decision-making for clinicians and owners., (Copyright and/or publishing rights held by the Canadian Veterinary Medical Association.)