523 results on '"Callaghan, Richard"'
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2. Biochemical interactions between the Atm1-like transporter from Novosphingobium aromaticivorans and heavy metals
3. Vinca alkaloid binding to P-glycoprotein occurs in a processive manner
4. Exploiting the metabolic energy demands of drug efflux pumps provides a strategy to overcome multidrug resistance in cancer
5. The utilisation of glutamine and glucose by a 3-D tumour model trapped in quiescence
6. Regulation of ABCG4 transporter expression by sterols and LXR ligands
7. Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane
8. The Strategic Location of the Maldives in Indian Ocean Maritime Trade and Colonization
9. Craniofacial morphology does not support a pre-contact Carib “invasion” of the northern Caribbean
10. Methods of reconstitution to investigate membrane protein function
11. Comments on the Mainland Origins of the Preceramic Cultures of the Greater Antilles
12. Dual effects of the PI3K inhibitor ZSTK474 on multidrug efflux pumps in resistant cancer cells
13. Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species
14. Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein
15. Just How and Where Does P-glycoprotein Bind All Those Drugs?
16. Using seafaring simulations and shortest-hop trajectories to model the prehistoric colonization of Remote Oceania
17. Regulation of P-Glycoprotein in the Brain
18. Improving the stability and function of purified ABCB1 and ABCA4: The influence of membrane lipids
19. Corrigendum to “Regulation of ABCG4 transporter expression by sterols and LXR ligands” [PMID: 33141061, DOI: 10.1016/j.bbagen.2020.129769]
20. Drift voyages across the mid-Atlantic
21. Overcoming ABCG2-mediated drug resistance with imidazo-[1,2-b]-pyridazine-based Pim1 kinase inhibitors
22. Survivin isoform Delta Ex3 regulates tumor spheroid formation
23. Collateral sensitivity as a strategy against cancer multidrug resistance
24. The Binding of Auxin to the Arabidopsis Auxin Influx Transporter AUX1
25. Examining Prehistoric Migration Patterns in the Palauan Archipelago: A Computer Simulated Analysis of Drift Voyaging
26. Metabolic Alterations During the Growth of Tumour Spheroids
27. Just How and Where Does P-glycoprotein Bind All Those Drugs?
28. The Use of Simulation Models to Estimate Frequency and Location of Japanese Edo Period Wrecks Along the Canadian Pacific Coast
29. The Ubiquitin E3 Ligase Nedd4 Regulates the Expression and Amyloid-β Peptide Export Activity of P-Glycoprotein
30. Ceramic Age Seafaring and Interaction Potential in the Antilles: A Computer Simulation 1
31. The stabilisation of purified, reconstituted P-glycoprotein by freeze drying with disaccharides
32. Purification and structural analyses of ABCG2
33. Examining dispersal mechanisms for the translocation of chicken ( Gallus gallus) from Polynesia to South America
34. Estimating trajectories of colonisation to the Mariana Islands, western Pacific
35. The Ortoiroid
36. St. Vincent
37. Seafaring Simulations
38. Accumulation and distribution of doxorubicin in tumour spheroids: the influence of acidity and expression of P-glycoprotein
39. Exploring the possible interaction between anti-epilepsy drugs and multidrug efflux pumps; in vitro observations
40. The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis
41. 1,3‐Benzodioxole‐Modified Noscapine Analogues: Synthesis, Antiproliferative Activity, and Tubulin‐Bound Structure
42. Review/Drug Metabolism and Transport: P-glycoprotein: So Many Ways to Turn It On
43. Archaeological Views of Caribbean Seafaring
44. How can we best use structural information on P-glycoprotein to design inhibitors?
45. Definition of the domain boundaries is critical to the expression of the nucleotide-binding domains of P-glycoprotein
46. The Flippase Delusion?
47. Prehistoric trade between Ecuador and West Mexico: a computer simulation of coastal voyages
48. Diffusivity and distribution of vinblastine in three-dimensional tumour tissue: Experimental and mathematical modelling
49. Repacking of the transmembrane domains of P‐glycoprotein during the transport ATPase cycle
50. The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influence
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