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1. Anorectal melanoma: a rare entity

Author

Relvas, Luis Miguel, Gago, Tania, Velasco, Francisco, Barros, Sonia, Carvalho, Isabel Malta, and Caldeira, Paulo

Published
2024

2. I-CARE, a European Prospective Cohort Study Assessing Safety and Effectiveness of Biologics in Inflammatory Bowel Disease

Author

Gornet, Jean-Marc, Beaugerie, Laurent, Shaji, Sebastian, Peyrin-Biroulet, Laurent, Reimund, Jean-Marie, Hebuterne, Xavier, Amiot, Aurélien, Armelao, Franco, Blanc, Pierre, Papi, Claudio, De Chambrun, Guillaume Pineton, Roblin, Xavier, Chu, Karmiris, Konstantinos, Shariq, Sohail, Viazis, Nikolaos, Limdi, Jimmy, Eder H, Piotr, Michalopoulos, Georgios, Bell, Andrew, Biancone, Livia, Dewitte, Marie, Mazhar, Zia, Franchimont, Denis, Nancey, Stephane, Macaigne, Gilles, Principi, Maria Beatrice, Fumery, Mathurin, Parkes, Gareth, Valats, Jean-Christophe, Doherty, Glen, Bouguen, Guillaume, Molnar, Tamás, Tsai, Hersin, Gangi, Mohsin, Pedersen, Natalia, Heluwaert, Frédéric, Shenderey, Richard, Zeissig, Sebastian, Butterworth, Jeffrey, Castiglione, Fabiana, Corless, Lynsey, Zallot, Camille, Baert, Filip, Singh, Salil, Sonwalkar, Sunil, Clayton, Elizabeth, Rahier, Jean-François, Vani, Deven, Bellaiche, Guy, De Vos, Martine, Kirchgesner, Julien, Kopylov, Uri, Lobaton, Triana, Locher, Christophe, Mantzaris, Gerassimos, Abouda, George, Smith, Katie, Sprakes, Michael, Theodoropoulou, Angeliki, Wesley, Emma, Bonnet, Joëlle, Elphick, David, Gilletta, Cyrielle, Gordon, John, Laharie, David, Nakad, Antoine, Orlando, Ambrogio, Dubois, Patrick, Hasselblatt, Peter, Michiels, Christophe, Preston, Cathryn, Staicu, Anca, Vuitton, Lucine, Kaassis, Mehdi, Speight, Ally, Ghosh, Deb, Löwenberg, Mark, Mathieu, Nicolas, Pelletier, Anne-Laure, Phillips, Anne, Magro, Fernando, Altwegg, Romain, Avni, Irit, biron, Landy, Jonathon, Nachury, Maria, Shenoy, Achuth, Trang, Caroline, Abitbol, Vered, Bamias, Georgios, Farkas, Klaudia, Maaser, Christian, Shitrit, Ariella, Siegmund, Britta, Filippi, Jérôme, O'morain, Colm, Yanai, Henit, Costes, Laurent, Hobday, David, Szepes, Zoltán, Calabrese, Emma, Dallal, Helen, Fung, Michael, Ramadas, Arvind, Baburajan, Bijay, Koss, Konrad, Barberis, Christophe, Buisson, Anthony, Amil, Morgane, Balestrieri, Paola, Johnson, Matthew, Tzouvala, Maria, Viennot, Stéphanie, Nagy, Ferenc, Thompson, Nick, Alric, Laurent, Samuel, Sunil, Bourrier, Anne, Chanteloup, Elise, Del Tedesco, Emilie, Harbord, Marcus, Lobo, Alan, Myers, Sally, Pollok, Richard, Ahmad, Tariq, Chaudhary, Rakesh, Karakoidas, Christos, Soliman, Ashraf, Stefanescu, Carmen, Theocharis, Georgios, Branden, Stijn Vanden, Beltran, Belén, Bouhnik, Yoram, Bourreille, Arnaud, Branco, Joana, Colleypriest, Ben, Eliakim, Rami, Knight, Paul, O'toole, Aoibhlinn, Robles, Virgina, Triantafyllou, Konstantinos, Bosca, Marta Maia, Lambrecht, Guy, Mosquera, Lucia Marquez, Panter, Simon, Pappa, Aikaterini, Simon, Marion, Sivaji, Ganesh, Bellanger, Christophe, Belle, Arthur, Borruel, Natalia, Egan, Laurence, Peeters, Harald, Sharpstone, Daniel, Arasaradnam, Ramesh, Benitez, José Manuel, Dahlerup, Jens Frederik, Giouleme, Olga, Gisbert, Javier P., Helwig, Ulf, Minguez, Miguel, Tsironi, Eftychia, Variola, Angela, Allen, Patrick, Boivineau, Lucille, Cole, Andy, Dib, Nina, Gomollon, Fernando, Johnston, Richard, Katsanos, Konstantinos, Kennedy, Nick, Kiszka-Kanowitz, Marianne, Marin-Jimenez, Ignacio, Miheller, Pál, Nos, Pilar, Saraj, Othman, Vinter-Jensen, Lars, Zittan, Eran, Baudry, Clotilde, Calvet, Xavier, Cazelles-Boudier, Marie-Christine, Coenegrachts, Jean-Louis, Cullen, Garret, Daperno, Marco, Dhar, Anjan, Gerard, Romain, Jensen, Nanna, Maharshak, Nitsan, Mcalindon, Mark, Mcloughlin, Simon, Parkes, Miles, Patel, Kamal, Peixoto, Armando, Polymeros, Dimitrios, Portela, Francisco, Rocca, Rodolfo, Seksik, Philippe, Subramanian, Sreedhar, Tennenbaum, Ruth, Atreya, Raja, Bachmann, Oliver, Berger, Arthur, Bor, Renáta, Buckley, Maire, Carpio, Daniel, Chaparro, María, Costa, Francesco, Domenech, Eugeni, Esteve, Maria, Foley, Stephen, Guardiola, Jordi, Koutroubakis, Ioannis, Kuehbacher, Tanja, Landman, Cécilia, Lavagna, Alessandro, Manceñido, Noemí, Mañosa, Míriam, Martín-Arranz, Maria Dolores, Plastaras, Laurianne, Scribano, Maria Lia, Sengupta, Subhasish, Teich, Nils, Tran-Minh, My-Linh, Zampeli, Evanthia, Amininejad, Leila, Arroyo, Teresa, Attar, Alain, Backman, Ann-Sofie, Bálint, Anita, Beckly, John, Ben Horin, Shomron, Bernardo, Sónia, Caillo, Ludovic, Caron, Bénédicte, Shanika de Silva, María, FábiáN, Anna, Fiorino, Gionata, Gutierrez, Ana, Lahat, Adi, Masmoudi, Mohamed, Mendolaro, Marco, Muls, Vinciane, Poullenot, Florian, Probert, Christopher, Reenaers, Catherine, Rutka, Mariann, Sarwari, Zaman, Sayer, Joanne, Sicilia, Beatriz, Sousa, Helena, van Kemseke, Catherine, Zabana, Yamile, Astegiano, Marco, Banim, Paul, Bettenworth, Dominik, Boualit, Médina, Brodersen, Jacob Broder, Christidou, Angeliki, Cooney, Rachel, Pinto, João Cortez, Cravo, Portugal Marília, Cremer, Anneline, Danese, Silvio, di Sabatino, Antonio, Fallingborg, Jan, Ferronato, Antonio, Planella, Esther Garcia, Gupta, Sanjay, Halfvarson, Jonas, Israeli, Eran, Kestenbaum, Samantha, Larsen, Lone, Macken, Elisabeth, Mathou, Nicoletta, Milassin, Ágnes, Pofelski, Joanna, Ricci, Chiara, Rodriguez-Moranta, Francisco, Schmidt-Lauber, Martin, Shaw, Ian, Soares, Marta, Soliman, Heithem, Triantos, Christos, Zografos, Konstantinos, Agrawal, Anurag, Armuzzi, Alessandro, Aubourg, Alexandre, Acosta, Manuel Barreiro-de, Barrio, Jesús, Bergemalm, Daniel, Bermejo, Fernando, Bodini, Giorgia, Bohr, Johan, Bossuyt, Peter, Christodoulou, Dimitrios, Claessens, Christophe, Collins, Paul, de Francisco, Ruth, Garcia, Santiago, Georgopoulos, Sotirios, Goutorbe, Felix, Kalantzis, Chrisostomos, Kourikou, Anastasia, Mace, Vincent, Malamut, Georgia, Ministro, Paula, Larmurier, Isabelle Nion, Ricart, Elena, Serrero, Mélanie, Sheridan, Juliette, Weimers, Petra, Andersen, Vibeke, Arroja, Bruno, Bokemeyer, Bernd, Bujanda, Luis, Degand, Thibault, Eriksson, Carl, Garceau, Cécile, Glerup, Henning, Goren, Idan, Jackson, Lucina, Koch, Stéphane, Mesonero, Francisco, Ordas, Ingrid, Riviere, Pauline, Saibeni, Simone, Soares, João, Tavernier, Noémie, Theede, Klaus, Ungar, Bella, Bästlein, Elke, Gasbarrini, Antonio, Protopapas, Andreas, Reindl, Wolfgang, Bossa, Fabrizio, Hart, Ailsa, Heil, Franz-Josef, O'Connor, Anthony, Oldenburg, Bas, Pastorelli, Luca, Stephen patchett, Ramakrishnan, Subramaniam, de Caestecker, John, Echarri, Ana, Kevans, David, Büning, Jürgen, Coelho, Rosa, Jansen, Jeroen, Koslowski, Benjamin, Wells, Christopher, Ceballos, Daniel, König, Ingrid, Padmanabhan, Hari, Patani, Timi, Qureshi, Raheel, Zagorowicz, Edyta, Allez, Matthieu, Archavlis, Emmanouil, Bonnet, Delphine, Guidi, Luisa, Mcnamara, Deirdre, Vernia, Piero, Weidenhiller, Michael, Alon, Lang, Boysen, Trine, Delattre, Charlotte, Farrell, Richard, Krüger, Rolf-Achim, Paupard, Thierry, Vind, Ida, Caprioli, Flavio, Gancho, Vladimir, Quentin, Vincent, Avidan, Benjamin, D’Haens, Geert, Mccarthy, Jane, Snook, Jonathon, Soufleris, Konstantinos, Zerbib, Frank, Carter, Dan, Depla, Annekatrien, Eisenbach, Thomas, Fries, Walter, Grammatikos, Nikolaos, Ilegems, Saskia, Lopez-Sanroman, Antonio, Moreau, Jacques, Riegler, Gabriele, Rietdijk, Svend, Rocha, Marta, Rosa, Isabelle, Ryan, Barbara, Yeremenko, Yelena, Boruchowicz, Arnaud, Damião, Filipe, Laoudi, Foteini, Lügering, Andreas, Macarri, Giampiero, Thomopoulos, Konstantinos, Barros, Luísa, Blixt, Thomas, Garros, Aurélien, Khorrami, Sam, Sokol, Harry, Sturm, Andreas, Livovsky, Dan, Maul, Jochen, Miks, Heinrich, Papadopoulos, Vasileios, Schmidt, Carsten, Snir, Yifat, Svenningsen, Lise, Ahmed, Wafaa, Broitman, Yelena, Cuillerier, Emmanuel, Kant, Prashant, Leyden, Jan, Lichtenstein, Lev, Lopes, Susana, Martineau, Chloé, Mulcahy, Hugh, Schweitzer, Axel, Van Schaik, Fiona, Banai, Hagar, Danion, Pauline, Dulery, Charlotte, Fidder, Herma, Gay, Claire, Hagege, Hervé, Harnois, Florence, Jørgensen, Søren Peter, Müller-Ziehm, Jens, Oikonomou, Michail, Palmela, Carolina, Schulze/Röske, Jörg, Smith, Mark, Thurm, Tamar, Bresso, Francesca, Brixi, Hedia, Jones, John, Macmathuna, Padraig, Painchart, Claire, Ron, Yulia, Vester-Andersen, Marianne, Alexandrino, Gonçalo, Börner, Norbert, Cardoso, Mariana, Chagas, Cristina, Dignaß, Axel, Dotan, Iris, Hedin, Charlotte, Karatzas, Pantelis, Kasapidis, Panagiotis, Palatka, Károly, Sakizlis, Georgios, Wilson, Ana, Bosanko, Nick, Caldeira, Paulo, Gagniere, Charlotte, Libier, Louise, Meunier, Camille, Moog, Gero, Pasquion, Audrey, Pica, Roberta, Akbar, Ayesha, Arab, Nadia, Cadiot, Guillaume, Carvalho, João, Charpignon, Claire, Fellermann, Laus, Fishman, Sigal, Fraser, Gerald, Gluck, Nathan, Hoesl, Mark, Kierkus, Jarosław, Klopocka, Maria, Arranz, Eduardo Martin, Menchen, Luis, Nikolaus, Susanna, Petrache, Anca, Ponsioen, Cyriel, Riestra, Sabino, Robledo, Pilar, Rodriguez, Cristina, Samer, Misheal, Tischer, Matthias, Wypych, Joanna, Baudon, Julien, Bezzio, Cristina, Boschetti, Gilles, Burisch, Johan, Creed, Tom, Demarzo, Maria Giulia, Festa, Stefano, Figueroa, Andrés, Julsgaard, Mette, Navarro, Pablo, Perez-Galindo, Pablo, Rouillon, Cléa, Sablich, Emanuele, Tosca, Joan, Vidon, Mathias, Vidon, Marine, Vitte, René-Louis, Wampach, Anne, Baumann, Cédric, Urmes, Isabelle Clerc, Rousseau, Hélène, Borie, Marc, Uzzan, Mathieu, Chatten, Kelly, Peter, Rimmer, Tariq, Iqbal, Cossignani, Marta, Cañete, Fiorella, Holvoet, Tom, Krasz, Susanne, Dias, Sandra, Abalia, Hadas, Abaza, Aziza, Abramovich, Gal, Ackzell, Ingrid, Adams, Carol, Addleton, Catherine, Alfambra, Erika, Algaba, Alicia, Allcock, Clare, Allison, Joanna, Amouriaux, Karine, Anderson, Julie, Anderson, Emma, Appelmans, Saskia, Armstrong, Lisa, Atkins, Stacey, Attaran-Bandarabadi, Masoumeh, Bailey, Yvonne, Bardot, Stephanie, Beck, Natasha, Bennett, Lillie, Bergfeld, Jonathan Phil, Berkane, Ramdane, Boey, Hanne, Bowlas, Louise, Bradley-Potts, Joanne, Brear, Tracy, Bretlander-Peters, Nicole, Brown, Ellen, Brown, Johanna, Buckingham, Elizabeth, Buellens, Katrien, Bull, Rhian, Burke, Maura, Burns, Leighanne, Burton, Julie, Bwalya, Agness, Cabanas, Karine, Callaghan, Muriel, Camou, Océane, Campbell, Debbie, Capoferro, Elvira, Carnahan, Mandy, Carnio, Cornelia, Carter, Anne, Clack, Concetta Casali, Chedouba, Leïla, Cipriano, Bessie, Claeys, Sophie, Closset, Manon, Coban, Dilek, Cococcia, Sara, Coe, Carolann, Cole, Helen, Collet, Emilie, Collins, Kayleigh, Combes, Isabelle, Connor, Emma, Constantin, Kathryn, Cooke, Susan, Cornet, Nathanaëlle, Corrihons, Estelle, Corsino, Pilar, Cortaville, Rosie, Cotterill, Donna, Cowton, Amanda, Cox, Harriet, Cripps, Viktoria, Crowder, Amanda, Cukier, Tzufit, Daniel, Amelia, Dawe, Chris, de Haan, Jose, Croix, Rosanna de la, Dejonckheere, Evva, Villanegro, Juan Delare, Delaval, Guillaume, Delliponti, Mariangela, Delommez, Aude, Detry, Emilie, Dhanaratne, Melanie, Galan, Laura Diez, Dodel, Marie, Dooks, Emma, Du Cheyron, Joseph, Duane, Linda, Vulgo Cochran, Jennifer Dulling, Dyer, Simona, Dymond, Harvey, Ekblad, Charlotte, Elliott, Kerry, Emmerson, Ingrid, Eugene-Jolchine, Irène, Fleming, Lorna, Fletcher, Eve, Ford, Sarah, Forshaw, Greg, Foulds, Angela, Francois, Caroline, Fuge, Nicole, Gafni, Gal, Ganon, Miri, Nuñez, Olga Garcia, Ramirez, Laura Garcia, Gelder, Sophie, Gettkowski, Raimonda, Gilardi, Daniela, Giuffrida, Paolo, Gobert, Vincent, Godden, Jo, Godwin, Nuala, Goulden, Kay, Graham, Sharon, Green, Charlotte, Green, Marie, Gueye, Aboubakar, Guler, Tuba, Gustavsson, Ida, Hadjisavvas, Helena, Hammonds, Fiona, Hantzi, Christina, Hauke, Marion, Haydock, Julie, Hayes, Orla, Nislev, Lizette Helbo, Hochstodter, Jessica, Hogg, Ashleigh, Hölbing, Manuela, Holland, Maureen, Holsbergen, Maartje, Howard, Linda, Hoyda, Aviya, Hull, Robert, Irish, Jane, Jackson, Wendy, Janssen, Wendy, Jeffrey, Lesley, Jourdan, Sofia, Jutrowska, Izabela, Kaniel, Chava, Karezos, Theofilos, Kelly, Niamh, Kelly, Jessica, Kennedy, Mary, Kennedy, Una, Kibaru, Joyce, Kirkman, Gemma, Klaproth, Janine, Kneese, Corinna, Koch, Andrea, Kokke, Kathleen, Koppelow, Martha, Krause, Sabine, Krauspe, Sabine, Kwakkenbos, Petra, Labarile, Nunzia, Lang, Hannah, Lassailly, Marianne, Leconte, Martine, Lepczynski, Linda, Levell, Emma, Levhar, Nina, Lindhort, Kerstin, Lisle, Jessica, Cauce, Beatriz Lopez, Lorenz, Gabriele, Lovati, Ambra, Lowry, Tracey, Lund, Margareta, Vorderbrügge, Anne Lutz, Maansson, Suzanne, Madapathage, Videsheka, Cheviakoff, Maelys, Magness, Alison, Manley, Orla, Manyoni, Catherine, Marg, Ingke, Marra, Antonella, Martins, Carole, Massella, Arianna, Mathias, Aurore, Mervyn, Danielle, Minsart, Charlotte, Mitchell, Sally, Monks, Kathleen, Montero, Mélanie, Moore, Alson, Moser, Maren, Moss, Alison, Mullen, Angela, Murciano, M. Francisca, Naylor, Deanna, Nehus, Ansgar, Nicholson, Anne, Nöding, Sarah, Nolan, Sinead, Nörenberg, Janet, Northcott, Clare, O'Connell, Jim, O’Kelly, Alison, Orbach-Zingboim, Noam, Orobitg, Judit, Otieno, Charlene, Owen, Charlotte, Patch, Sarah, Pauker, Maor, Pauli, Renate, Pearson, Harriet, Peggy, Falgon, Petit, Séverine, Petrissans, Christine, Piergallini, Simona, Pippard, Lucy, Pitt, Laura, Pócsik, Gabriella, Poher, Yoann, Pomes, Chloé, Pritchard, Lucy, Puchades, Laura, Quaid, Sheena, Rana, Aleem, Raynard, Dana, Reilly, Mykla, Reinert, Sonja, Reinknecht, Manuela, Renner, Baerbel, Reynolds, Rob, Rizzuto, Giulia, Robinson, Matthew, Robrechts, Joke, Rodriguez, Eva M., Rosenblum, Efrat, Russel, Tamlyn, Sadare, Ibiyemi, Salama, Noa, Schakel, Toos, Schauer, Anja, Schiavoni, Elisa, Shaw, Caroline, Shelton, Sarah, Sicart, Virginie, Siouville, Elodie, Smith, Orla, Soude, Théo, Stephenson, Sophie, Stephenson, Elaine, Steppe, Marjan, Sterkx, An, Stickley, Jo, Sugrue, Kathleen, Swietec, Natalia, Tasiaux, Charlotte, Thamu, Bhavneet, Thomas, Susane, Tobi, Ogwa, Touabi, Kahina, Tovi, Shifra, Tregonning, Julie, Turchini, Laura, Unkhoff, Julia, Unruh, Olesya, Uzun, Nurcan, Van Aert, Frauke, Bergh, Sandrine Vanden, Vandenbroucke, Louise, Vansteenkiste, Laura, Vardit, Shay, Vergriete, Valentin, Walker, Elaine, Warner, Eleanor, Watchorn, Olivia, Watson, Ekaterina, Wauthier, Marie-Claire, Weetman, Belgium Maria, Weston, Margaret, West-Petroschka, Wiebke, Wienecke, Susann, Wierling, Kerstin, Wiestler, Miriam, Wilcox, Rebecca, Wilhelmsen, Elva, Williams, Angharad, Williamson, Georgina, Wilson, Deborah, Wistance, Kate, Wortmann, Nicolas, Wurie, Subie, Yadgar, Karin, Young, Gail, Young, Megan, Aucouturier, Julien, Bertin, Marie- Jo, Bougrine, Hasnae, Coisnon, Marie, Defrance, Antoine, Gutierrez, Kati, Harouz, Amel, Jerber, Laure, Khlifi, Aida, Kirati, Amina, Liworo, Nasaladjine, Logoltat, Maude, Mailhat, Charlotte, M'Bayi, Chancely, Medane, Yasmina, Merkhoufa, Dalal, Elhad, Saouda Mohamed, Monthe, Bertille, Moyon, Fanny, Rabiega, Pascaline, Sekela, Jennifer, Thilloy, Charlotte, Hamamouche, Naima, Partisotti, Frederic, Blandin, Patrick, Mokhtari, Hocine, Coutard, Laure, and Doherty, Glen A.

Published
2023
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4. Treat to target versus standard of care for patients with Crohn's disease treated with ustekinumab (STARDUST): an open-label, multicentre, randomised phase 3b trial

Author

Rocca, Rodolfo, Lopes, Susana, Caprioli, Flavio, Ardizzone, Sandro, Echarri Piudo, Ana, Gionchetti, Paolo, Roblin, Xavier, Seidler, Ursula, Andersson, David, Patel, Kamal, Desreumaux, Pierre, Saibeni, Simone, From, Gustav, Fedurco, Miroslav, Gregus, Milos, Bouhnik, Yoram, Luegering, Andreas, Cosintino, Rocco, Bunganic, Ivan, Ramos, Jaime, Aguas Peris, Mariam, Dewit, Olivier, Principi, Mariabeatrice, Wesley, Emma, Lago, Paula, Nancey, Stephane, Martín Arranz, María Dolores, Hindryckx, Pieter, Orlando, Ambrogio, Geccherle, Andrea, Annunziata, Maria Laura, Hayee, Bu'hussain, Balaz, Jozef, Portela, Francisco, Gilletta, Cyrielle, Kucharzik, Torsten, Mínguez, Miguel, Gisbert, Javier Pérez, Casbas, Ana Gutiérrez, Louis, Edouard, Marino, Marco, Parkes, Gareth, Cummings, Fraser, Jharap, Bindia, Kjeldsen, Jens, Correia, Luís, Ministro, Paula, Ebert, Matthias, Hertervig, Erik, Staessen, Dirk, Dutré, Joris, Colard, Arnaud, Morrison, Graham, Glerup, Henning, Dahlerup, Jens Frederik, Wolfhagen, Frank, Batovsky, Marian, Molnar, Martin, Kadleckova, Barbora, Caldeira, Paulo, Laharie, David, Hebuterne, Xavier, Bonaz, Bruno, Allez, Matthieu, Fischer, Andreas, Hinojosa Del Val, Joaquín Ernesto, Ciria, Miriam Mañosa, Herrera Justiniano, Jose Manuel, Soderman, Charlotte, Chandy, Rajiv, Mowat, Craig, Irving, Peter, Fallingborg, Jan, Matous, Jan, Douda, Tomas, Altwegg, Romain, Benitez, Jose Manuel, Arroyo Villarino, María Teresa, Capón, Jordi Guardiola, Vicenc, Daniel Ginard, Dewint, Pieter, Almer, Sven, Kindt, Sebastien, Danese, Silvio, Vermeire, Severine, D'Haens, Geert, Panés, Julian, Dignass, Axel, Magro, Fernando, Nazar, Maciej, Le Bars, Manuela, Lahaye, Marjolein, Ni, Lioudmila, Bravata, Ivana, Lavie, Frederic, Daperno, Marco, Lukáš, Milan, Armuzzi, Alessandro, Löwenberg, Mark, Gaya, Daniel R, and Peyrin-Biroulet, Laurent

Published
2022
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7. How functional movement variability facilitates successful skill adaptation during the volleyball attack.

Author

Caldeira, Paulo, Paulo, Ana, Veloso, António, Infante, Jorge, Davids, Keith, and Araújo, Duarte

Subjects
VOLLEYBALL, ECOSYSTEM dynamics, VOLLEYBALL players, LOGISTIC regression analysis, REGRESSION analysis
Abstract

From an ecological dynamics perspective, careful manipulation of task constraints can provide opportunities for action, exploited by functional movement variability of participants. The constraints-led approach (CLA) induces functional movement variability in practice designs, supporting athlete performance in satisfying task constraints and finding performance solutions to achieve intended task goals. Young male volleyball players were randomly assigned to either a traditional approach (TA) or CLA practice group. Selected spatial-temporal movement coordination variables were recorded, to explore their relations to successful performance outcomes in the attacking phase. Binomial logistic regression was used to verify the association of spatial-temporal movement variables with the percentage of successful attacks. Six spatial-temporal variables were included, and a manual backward stepwise regression was used to remove those which did not contribute to the best predictive model of successful performance. After a 6-week intervention programme, the CLA practice group displayed a significantly higher percentage of successful attack actions, when facing the opposition block. The TA group showed a small increase in successful attack actions after the intervention. The final binomial logistic regression model revealed that the variables 'lateral deviation of the participants' centre of mass' at the planting step and 'longitudinal deviation of the participants' centre of mass' at point of ball contact were the main predictors of successful attacking outcomes. To overcome the opposition's block in volleyball, infusing functional variability in a CLA task design, promoted superior performance in practice. Presumably, greater movement pattern variability emerged in participants to satisfy performance constraints in successful volleyball attacks. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Deslocamento de abomaso : fatores implicados na sobrevivência após cirurgia corretiva

Author

Caldeira, Paulo Jorge Ramos, Bexiga, José Ricardo Dias, and Guerreiro, Dário Alexandre de Sá (Tutor)

Subjects
Transition period, Deslocamento de abomaso, BHB sérico, Abomasal displacement, Dairy cow, Serum BHB, Maneio alimentar, Período de transição, Vaca leiteira, Feed management
Abstract

Dissertação de Mestrado Integrado em Medicina Veterinária, na área científica de Clínica O melhoramento genético para a produção leiteira tem sido constante ao longo dos últimos anos, o que tem levado à preferência por animais com uma grande capacidade digestiva e uma maior profundidade corporal. O deslocamento de abomaso é o distúrbio abomasal mais frequente e representa a razão mais habitual para cirurgia abdominal em bovinos leiteiros, principalmente vacas de elevada produção. A etiologia do deslocamento de abomaso é considerada multifatorial, sendo que a acumulação de gás e a distensão do órgão, devido a hipomotilidade ou atonia abomasal, são pré-requisitos para que estes ocorram. Esta doença apresenta elevados prejuízos económicos, na medida em que existem custos com tratamentos, diminuição da produção leiteira, perda de peso, aumento do intervalo entre partos, descarte de leite ou até mesmo a morte ou refugo do animal. O parto apresenta ser a condição que mais frequentemente predispõe ao deslocamento de abomaso à esquerda. Também a cetose e outras doenças metabólicas apresentam correlação positiva com a ocorrência desta doença. O tratamento pode ser dividido em tratamento clínico e tratamento cirúrgico. O tratamento clínico apresenta como objetivo a restauração da motilidade abomasal, para que seja possível a expulsão do gás no interior do órgão. Este tipo de tratamento apenas é indicado em casos que os animais não apresentem sinais clínicos sistémicos, porém apresenta uma elevada taxa de recidiva. O tratamento cirúrgico tem como função a reposição do órgão na sua posição anatómica correta e a criação de uma fixação permanente. Pode ser dividido em dois grandes grupos: os métodos fechados ou minimamente invasivos e os métodos abertos ou invasivos. O estudo contou com 26 animais de uma exploração do concelho da Moita. Destes animais apenas 2 (7,7%) não sobreviveram no período de 10 dias após a cirurgia corretiva. No que diz respeito no período de 90 dias após a cirurgia, 4 vacas (15,4%) não sobreviveram. Os animais incluídos neste estudo contavam com uma idade média de 3,11 anos, uma lactação, um intervalo entre partos médio de 470 dias, uma condição corporal média de 3,25, uma média de BHB sérico de 1,25 mmol/L e um pH médio do líquido abomasal de 2,5. Não foi encontrada nenhuma correlação estatisticamente significativa entre os parâmetros estudados, como os níveis séricos de BHB, o IEP, a CC e o pH do líquido abomasal ABSTRACT - ABOMASAL DISPLACEMENT: FACTORS INVOLVED IN SURVIVAL AFTER CORRECTIVE SURGERY - Genetic improvement for dairy production has been constant over the last few years, which has led to a preference for animals with a great digestive capacity and greater body depth. Abomasal displacement is the most frequent abomasal disorder and represents the most usual reason for abdominal surgery in dairy cattle, especially high production cows. The etiology of abomasal displacement is considered multifactorial, with gas accumulation and distension of the organ due to abomasal hypomotility or atony being prerequisites for its occurrence. This disease presents high economic losses, as there are costs with treatments, decrease in milk production, weight loss, increase in the interval between calving, discarding of milk or even the death or slaughter of the animal. Calving is the condition that most often predisposes to left abomasal displacement. Ketosis and other metabolic diseases also present a positive correlation with the occurrence of this disease. The treatment can be divided into clinical and surgical treatment. The objective of the clinical treatment is the restoration of abomasal motility, so that it is possible to expel the gas inside the organ. This type of treatment is only indicated in cases where the animals do not present systemic clinical signs, but it presents a high rate of recurrence. Surgical treatment has the function of restoring the organ to its correct anatomical position and creating a permanent fixation. It can be divided into two major groups: closed or minimally invasive methods, and open or invasive methods. The study included 26 animals from a farm in the municipality of Moita. Of these animals only 2 (7.7%) did not survive within 10 days after the corrective surgery. Regarding the period of 90 days after surgery, 4 cows (15.4%) did not survive. The animals included in this study had a mean age of 3.11 years, one lactation, a mean calving interval of 470 days, a mean body condition of 3.25, a mean serum BHB of 1.25 mmol/L and a mean abomasal fluid pH of 2.5. No statistically relevant correlation was found among the studied parameters such as BHB serum levels, calving interval, body condition, and pH of the abomasum liquid N/A

Published
2023

14. Impact of Early Surgery and Immunosuppression on Crohnʼs Disease Disabling Outcomes

Author

Magro, Fernando, Dias, Cláudia C., Coelho, Rosa, Santos, Paula M., Fernandes, Samuel, Caetano, Cidalina, Rodrigues, Ângela, Portela, Francisco, Oliveira, Ana, Ministro, Paula, Cancela, Eugénia, Vieira, Ana I., Barosa, Rita, Cotter, José, Carvalho, Pedro, Cremers, Isabelle, Trabulo, Daniel, Caldeira, Paulo, Antunes, Artur, Rosa, Isadora, Moleiro, Joana, Peixe, Paula, Herculano, Rita, Gonçalves, Raquel, Gonçalves, Bruno, Tavares Sousa, Helena, Contente, Luís, Morna, Henrique, and Lopes, Susana

Published
2017
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17. Treat to target versus standard of care for patients with Crohn's disease treated with ustekinumab (STARDUST): an open-label, multicentre, randomised phase 3b trial

Author

Danese, Silvio, primary, Vermeire, Severine, additional, D'Haens, Geert, additional, Panés, Julian, additional, Dignass, Axel, additional, Magro, Fernando, additional, Nazar, Maciej, additional, Le Bars, Manuela, additional, Lahaye, Marjolein, additional, Ni, Lioudmila, additional, Bravata, Ivana, additional, Lavie, Frederic, additional, Daperno, Marco, additional, Lukáš, Milan, additional, Armuzzi, Alessandro, additional, Löwenberg, Mark, additional, Gaya, Daniel R, additional, Peyrin-Biroulet, Laurent, additional, Rocca, Rodolfo, additional, Lopes, Susana, additional, Caprioli, Flavio, additional, Ardizzone, Sandro, additional, Echarri Piudo, Ana, additional, Gionchetti, Paolo, additional, Roblin, Xavier, additional, Seidler, Ursula, additional, Andersson, David, additional, Patel, Kamal, additional, Desreumaux, Pierre, additional, Saibeni, Simone, additional, From, Gustav, additional, Fedurco, Miroslav, additional, Gregus, Milos, additional, Bouhnik, Yoram, additional, Luegering, Andreas, additional, Cosintino, Rocco, additional, Bunganic, Ivan, additional, Ramos, Jaime, additional, Aguas Peris, Mariam, additional, Dewit, Olivier, additional, Principi, Mariabeatrice, additional, Wesley, Emma, additional, Lago, Paula, additional, Nancey, Stephane, additional, Martín Arranz, María Dolores, additional, Hindryckx, Pieter, additional, Orlando, Ambrogio, additional, Geccherle, Andrea, additional, Annunziata, Maria Laura, additional, Hayee, Bu'hussain, additional, Balaz, Jozef, additional, Portela, Francisco, additional, Gilletta, Cyrielle, additional, Kucharzik, Torsten, additional, Mínguez, Miguel, additional, Gisbert, Javier Pérez, additional, Casbas, Ana Gutiérrez, additional, Louis, Edouard, additional, Marino, Marco, additional, Parkes, Gareth, additional, Cummings, Fraser, additional, Jharap, Bindia, additional, Kjeldsen, Jens, additional, Correia, Luís, additional, Ministro, Paula, additional, Ebert, Matthias, additional, Hertervig, Erik, additional, Staessen, Dirk, additional, Dutré, Joris, additional, Colard, Arnaud, additional, Morrison, Graham, additional, Glerup, Henning, additional, Dahlerup, Jens Frederik, additional, Wolfhagen, Frank, additional, Batovsky, Marian, additional, Molnar, Martin, additional, Kadleckova, Barbora, additional, Caldeira, Paulo, additional, Laharie, David, additional, Hebuterne, Xavier, additional, Bonaz, Bruno, additional, Allez, Matthieu, additional, Fischer, Andreas, additional, Hinojosa Del Val, Joaquín Ernesto, additional, Ciria, Miriam Mañosa, additional, Herrera Justiniano, Jose Manuel, additional, Soderman, Charlotte, additional, Chandy, Rajiv, additional, Mowat, Craig, additional, Irving, Peter, additional, Fallingborg, Jan, additional, Matous, Jan, additional, Douda, Tomas, additional, Altwegg, Romain, additional, Benitez, Jose Manuel, additional, Arroyo Villarino, María Teresa, additional, Capón, Jordi Guardiola, additional, Vicenc, Daniel Ginard, additional, Dewint, Pieter, additional, Almer, Sven, additional, and Kindt, Sebastien, additional

Published
2022
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18. Constraints-led approach and synergetic behaviour in volleyball performance

Author

Caldeira, Paulo Jorge Pereira, Araújo, Duarte Fernando da Rosa Belo Patronilho de, and Infante, Jorge Manuel Castanheira

Subjects
Perceptual attunement, Synergies, Individual differences, Variabilidade funcional, Functional variability, Diferenças individuais, Ecological approach, Abordagem ecológica, Sinergias, Afinação perceptual, Ciências Sociais [Domínio/Área Científica]
Abstract

O objetivo desta tese foi investigar a Abordagem Baseada nos Constrangimentos (ABC) e comportamento sinergético no voleibol. Enquadrados pela dinâmica ecológica investigámos conceitos teóricos relacionados com o comportamento sinergético individual e coletivo e aplicamos a ABC em equipas de voleibol. Inicialmente, apresentámos uma revisão narrativa dos princípios da ABC e pedagogia não-linear sugerindo dois exemplos para aplicação em treino. De seguida, produzimos dois artigos de opinião sobre o papel das estruturas de biotensegridade no comportamento sinergético individual e coletivo. Nos estudos experimentais implementámos a ABC para guiar os atletas através das fases de “Search”, “Discover” e “Exploit”. Primeiro, numa equipa de cadetes feminina manipulámos os constrangimentos da tarefa de forma a respeitar as diferenças individuais e comparar a precisão no remate após o treino, assim como, analisar a estratégia temporal na estrutura coordenativa da corrida e chamada de remate. Os resultados mostram que respeitar as diferenças individuais promovem melhor performance (i.e., na precisão do remate) e que congelar os graus de liberdade numa componente da estrutura coordenativa da chamada foi a estratégia associada com mais precisão no remate. De seguida, implementámos um estudo com jogadoras peritas para comparar frequências de contacto na defesa entre o jogo formal, a estratégia tradicional de defesa e a estratégia de coletivamente atender a variáveis especificadoras no decorrer da jogada. Adicionalmente, medimos a sincronização da defesa em situações de sucesso e insucesso defensivo. Resultados mostram que coletivamente atender a variáveis especificadoras no decorrer da jogada promove maior frequência de contactos e que as jogadas de sucesso defensivo estão associadas a alterações na sincronização no decorrer da jogada. Por último, com jogadores jovens de elite comparámos os efeitos na performance de ataque entre treinar de acordo com os princípios da ABC e com uma abordagem tradicional. Também tivemos como objetivo predizer quais as variáveis espácio-temporais que foram exploradas pelos jogadores nos ataques com sucesso. Resultados mostram um aumento da performance com a ABC e que variabilidade na chamada e consistência no ponto de contacto da bola aumenta a probabilidade de atacar com sucesso. The aim of this thesis was to research the Constraints-led Approach (CLA) and synergetic behaviour in volleyball performance. Grounded on ecological dynamics framework we researched theoretically concepts related to individual and collective synergetic behaviour and experimentally implemented the CLA with volleyball teams. First, we presented a narrative review on the principles of CLA and nonlinear pedagogy providing two practical examples to apply to the sub-phase of volleyball attack. Next, we advanced a position statement and a novel hypothesis on the crucial role of biotensegrity structures in individual and collective coordinative structurers (i.e., synergies). In the experimental studies we implemented CLA to guide the performers trough the phases of “Search”, “Discover” and “Exploit”. First, with a team of young female volleyball players we manipulate task constraints to accommodate individual differences and compare spike accuracy after training as well as understand time strategies in the coordinative structure of the horizontal approach. Results show that accommodating individual differences enhances performance (i.e., spike accuracy) and freezing degrees of freedom maintaining high variability in a component of the coordinative structure of the horizontal approach was the strategy of movement re-organization associated with higher spike accuracy. Next, we implemented a study with expert female volleyball players to compare frequencies of defensive ball contacts between real game, traditional defense strategy and “online” attunement to specifying variables. Additionally, we measure group synchronization in successful and unsuccessful defense situations. Results show that collectively attuning to relevant information promotes significant higher frequencies of defense ball contact than pre-determined strategies of action and successful defensive plays are associated with “online” significant changes in group synchronization. Finally, with young male elite volleyball players we aimed to compare the effects of training based on CLA principles to a traditional approach on attack performance. Also, aimed to predict what spatial temporal variables were exploited by the players to achieve successful attacks. Results showed a significant improvement in attack performance for CLA, and we found that variability at the end of the planting step and consistency at ball contact increased the chances of a successful attack.

Published
2021

19. Self-Determination Theory and Nonlinear Pedagogy: An Approach to Exercise Professionals’ Strategies on Autonomous Motivation

Author

Zarazaga Raposo, Frederico, Caldeira, Paulo, Batalau, Rui, Araújo, Duarte, Silva, Marlene Nunes, Zarazaga Raposo, Frederico, Caldeira, Paulo, Batalau, Rui, Araújo, Duarte, and Silva, Marlene Nunes

Abstract

Promoting adherence to exercise, especially in a long-term, remains a critical issue in fitness and wellness (F&W) context. SelfDetermination Theory (SDT) and Non-Linear Pedagogy (NLP) have progressively established themselves as valid backgrounds for intervention in F&W context. Analysing the assumptions of both, seems to reveal points of contact and complementarities yet to be explored through experimental research. Autonomy, competence and relatedness are basic psychological needs (BPN) that motivational strategies based on SDT seek to satisfy, aiming autonomous self-regulation for exercise. NLP practice is centered in the performerenvironment system exhibiting tasks that should be representative of the context of performance with adaptive variability; tasks should be simplified rather than decomposed. Task, individual and environmental constraints are considered and manipulated to guide the performer through a learning process according to the individual differences, promoting cooperation and stimulating decision. Research has demonstrated the determining importance of the type of exercise professionals’ motivational practices, leading to a positive or negative impact on practitioners. These strategies may involve the diagnostic of action capabilities, and the use of Motivational Interview (MI) principles to facilitate the goal-setting process, manipulating task constraints, and using instructions as task constraints. The purpose of this manuscript is to discuss possibilities on how NLP can target autonomous motivation, based on SDT, resulting in a landscape of affordances for exercise and daily activities that promote autonomous motivation in the F&W context. To our better knowledge, NLP has never been considered neither in the scope of F&W, or as a facilitator of autonomous motivation., Promover la adhesión al ejercicio, es un problema en la condición física y bienestar (CF&B). La teoría de la autodeterminación (TAD) y pedagogía no lineal (PNL) se han consolidado como válidos para la intervención en la CF&B. Ambos parecen tener puntos de contacto y complementariedades aún por explorar a través de la investigación. La autonomía, competencia y relación son necesidades psicológicas básicas que las estrategias motivacionales basadas en TAD buscan satisfacer, con vista a la regulación autónoma para el ejercicio. La PNL se centra en el sistema de entorno del ejecutante que presenta tareas representativas del contexto con variabilidad adaptativa; Las tareas deben simplificarse y no descomponerse. Las restricciones de tareas, individuales y ambientales se manipulan para guiar al ejecutante a través de un proceso de aprendizaje de acuerdo con diferencias individuales, promoviendo la cooperación y estimulando la decisión. Se ha demostrado la importancia de estas prácticas motivacionales de profesionales y su impacto positivo o negativo. Estas estrategias pueden implicar con el diagnóstico de capacidades de acción, y el uso de los principios de la entrevista motivacional (EM) para facilitar el estabelecimiento de objetivos, manipulando las restricciones de tareas y utilizando las instrucciones como restricciones. El propósito de este manuscrito es discutir cómo puede la PNL enfocarse en la motivación autónoma, basada en el TAD, dando como resultado los recursos para el ejercicio y actividades diarias que promueven la motivación autónoma en la CF&B. Para nuestro conocimiento, la PNL nunca ha sido considerada en el CF&B, ni como facilitadora de la motivación autónoma.

Published
2020

20. Standards for Brazilian school libraries

Author

Campello, Bernadete, primary, Gonçalves Abreu, Vera Lúcia Furst, additional, Da Terra Caldeira, Paulo, additional, Barbosa, Ricardo Rodrigues, additional, Da Conceição Carvalho, Maria, additional, Duarte, Adriana Bogliolo Sirihal, additional, Araújo, Carlos Alberto Ávila, additional, Vianna, Márcia Milton, additional, Fialho, Janaína Ferreira, additional, and Alvarenga, Maura, additional

Published
2021
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22. Data on the evaluation of FGF2 gene expression in Colorectal Cancer

Author

Caiado, Helena, primary, Conceição, Natércia, additional, Tiago, Daniel, additional, Marreiros, Ana, additional, Vicente, Susana, additional, Enriquez, Jose Luis, additional, Vaz, Ana Margarida, additional, Antunes, Artur, additional, Guerreiro, Horácio, additional, Caldeira, Paulo, additional, and Cancela, M. Leonor, additional

Published
2020
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25. Evaluation of MGP gene expression in colorectal cancer

Author

Caiado, Helena, primary, Conceição, Natércia, additional, Tiago, Daniel, additional, Marreiros, Ana, additional, Vicente, Susana, additional, Enriquez, Jose Luis, additional, Vaz, Ana Margarida, additional, Antunes, Artur, additional, Guerreiro, Horácio, additional, Caldeira, Paulo, additional, and Cancela, M. Leonor, additional

Published
2020
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26. Supplemental_Material – Supplemental material for Soluble human Suppression of Tumorigenicity 2 is associated with endoscopic activity in patients with moderate-to-severe ulcerative colitis treated with golimumab

Author

Magro, Fernando, Lopes, Susana, Silva, Marco, Coelho, Rosa, Portela, Francisco, Branquinho, Diogo, Correia, Luís, Fernandes, Samuel, Cravo, Marília, Caldeira, Paulo, Sousa, Helena Tavares De, Patita, Marta, Lago, Paula, Ramos, Jaime, Afonso, Joana, Redondo, Isabel, Machado, Patrícia, Philip, George, Lopes, Joanne, and Carneiro, Fátima

Subjects
FOS: Clinical medicine, 111199 Nutrition and Dietetics not elsewhere classified, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, Supplemental_Material for Soluble human Suppression of Tumorigenicity 2 is associated with endoscopic activity in patients with moderate-to-severe ulcerative colitis treated with golimumab by Fernando Magro, Susana Lopes, Marco Silva, Rosa Coelho, Francisco Portela, Diogo Branquinho, Luís Correia, Samuel Fernandes, Marília Cravo, Paulo Caldeira, Helena Tavares de Sousa, Marta Patita, Paula Lago, Jaime Ramos, Joana Afonso, Isabel Redondo, Patrícia Machado, George Philip, Joanne Lopes and Fátima Carneiro in Therapeutic Advances in Gastroenterology

Published
2019
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27. A influência da pedagogia não-linear e da abordagem baseada nos constrangimentos no treino do remate no voleibol

Author

Caldeira, Paulo, Paulo, Ana, Infante, Jorge, Araújo, Duarte, Caldeira, Paulo, Paulo, Ana, Infante, Jorge, and Araújo, Duarte

Abstract

The objective of this article is to overview the principles of the constraints-led approach and nonlinear pedagogy and how they can be applied to volleyball training. To better structure volleyball training and enhance game performance are developed the principles of representative context, task manipulation, instructions based on external focus of attention highlighting the effects of the action and taking advantage on movement variability. In volleyball games, attack is responsible for the majority of points, which highlights the importance of training this tactical action in a representative context. We present two examples of how to apply the constraints-led approach and nonlinear pedagogy to the sub-phase of attack with block opposition., O objetivo deste artigo é rever os fundamentos teóricos da abordagem baseada nos constrangimentos e da pedagogia não-linear e como, de acordo com os seus princípios, poderá ser abordado o treino do voleibol. Neste sentido, para estruturar o treino de voleibol e melhorar o desempenho em jogo são desenvolvidos os princípios de manutenção do contexto ecológico, de manipulação da tarefa, de concentrar as instruções num foco externo valorizando os efeitos da ação e capitalizar a variabilidade do movimento. No voleibol o ataque é responsável pela maioria dos pontos efectuados, o que sublinha a importância do treino desta ação tática num contexto ecológico. São apresentados dois exemplos da aplicação da abordagem baseada nos constrangimentos e da pedagogia não-linear à subfase de ataque com oposição do bloco., El objetivo de este articulo es repasar los fundamentos teóricos del enfoque basado en los constreñimientos y de la pedagogía no-linear e como, según sus principios, podrá ser abordado el entrenamiento de voleibol. En este sentido, para estructurar el entrenamiento de voleibol y mejorar el desempeño en juego son desarrollados los principios de manutención del contexto ecológico, de manipulación de tarea, de concentrar las instrucciones en un foco externo valorizando los efectos de la acción. En el voleibol el ataque es responsable por la mayoría de los puntos efectuados, lo que subraya la importancia del entrenamiento de esta acción táctica en un contexto ecológico. Son presentados dos ejemplos de la aplicación del abordaje basado en los constreñimientos y de la pedagogía no-linear a la sub-fase de ataque con oposición de bloque.

Published
2019

29. Characterization of GTO's under different modes of zero current switching

Author

Mertens, Axel, Skudelny, Hans-Christoph, Caldeira, Paulo P.A., and Lipo, T.

Subjects
Power electronics -- Research, Thyristors -- Research, Semiconductor switches -- Research, Business, Electronics, Electronics and electrical industries
Abstract

In recent years, several papers described the use of GTO's in zero current switching (ZCS) applications, with the goal of increasing the frequency range for medium- and high-power converters. Zero current switching with GTO's can be applied in series and parallel resonant converters, as well as in PWM inverters with commutation aid networks. The voltage and current waveforms at the devices differ in each of these applications, and different modes of ZCS can be identified. In this paper, a comparative view of the behavior and characteristics of the GTO in the different modes of ZCS is presented. The variety of ZCS waveforms is described and transferred into a unifying schematic. The behavior of GTO's in the different modes of operation is characterized, and requirements to the circuit environment are pointed out. The relations between the most important circuit parameters and some of the device waveform parameters are investigated experimentally.

Published
1994

30. Utilization of the series resonant DC link converter as a conditioning system for SMES

Author

Marschke, Karl W., Caldeira, Paulo P.A., and Lipo, Thomas A.

Subjects
Magnetic energy storage -- Equipment and supplies, Power conditioning -- Research, Electric current converters -- Usage, Business, Electronics, Electronics and electrical industries
Abstract

In this paper a new superconductive magnetic energy storage (SMES) system utilizing a high-frequency series resonant dc link power converter of high efficiency as the conditioning converter is presented. This system generates a high-frequency (20 kHz or more) resonant current in a series link and switching is done at zero current instants, reducing switching losses to a minimal value. Through the utilization of an adequate control strategy, the input power factor can be fully adjusted during the charging, storing, and discharging modes of the SMES, improving the overall system efficiency. Different semiconductor devices are employed as the switching elements of the resonant converter and switching losses are established for each case. Experimental results from a monophase and three-phase system verified the results obtained from digital simulation.

Published
1992

31. Responsabilidade Social e Gestão Fiscal? O Caso da 'Missão Continente Sorriso'

Author

Caldeira, Paulo, Borrego, Ana, and Bandeira, Ana

Subjects
Benefícios fiscais, Mecenato social, Teoria da legitimidade, Teoria dos stokeholders, Fiscal management, Theory of legitimacy, Tax benefits, Gestão fiscal, Social patronage, Stokeholders theory, CSR, Ciências Sociais::Economia e Gestão [Domínio/Área Científica], RSE
Abstract

O interesse por este tema surgiu pelo facto de termos conhecimento que as iniciativas de Responsabilidade Social Empresarial (RSE) podem ter impactos fiscais favoráveis no contexto dos mecenas, pelo que foi escolhido um projecto de RSE da SONAE para realizar um estudo aplicado. Assim, este trabalho tem como principal objectivo determinar, na percepção dos consumidores, quais foram as motivações da SONAE para “apadrinhar” o projecto “O Livro das Melhores Receitas da Família”; para tal realizou-se um questionário a uma amostra de clientes do «Hipermercado Continente». O tratamento estatístico dos dados recolhidos permitiu verificar que a maioria dos inquiridos entende a RSE como uma forma de contribuir para o desenvolvimento da economia, melhorando a qualidade de vida dos trabalhadores e da sociedade em geral. Acresce que consideram que as principais motivações da SONAE para “apadrinhar” esta causa são o fortalecimento da sua imagem de marca e reputação empresarial, bem como o aproveitarem dos benefícios fiscais (BF) associados à mesma; BF dos quais cerca de metade dos inquiridos não tinha conhecimento de que o mecenas podia usufruir, contudo, não obstante considerarem esse facto inaceitável, um número considerável de inquiridos afirma que irá continuar a comprar o livro, apoiando esta causa The interest in this theme occurs due to the fact that we know that the Corporate Social Responsibility (CSR) initiatives can have favorable tax impacts in the sponsors’ context, so a CSR project from SONAE was chosen to carry out a study. Thus, this work has as main objective to determine, in the perception of the consumers, what were the motivations of SONAE to “sponsor” the project “The book of the better family recipes”; a questionnaire was applied on a sample of clients of the «Continente Hypermarket». The statistical treatment of the data collected showed that the majority of respondents consider CSR as a way to contribute to the development of the economy, improving the quality of life of workers and society in general. In addition, they consider that SONAE's main motivations for “patronizing” this cause are to strengthen of the image and business reputation, as well as to take advantage of the tax benefits associated, from which about half of the respondents were unaware that SONAE could benefit from them, however, even though they considered this to be unacceptable, a considerable number of respondents stated that they would continue to buy the book, supporting this cause

Published
2018

32. PROJETO DE DIAGNÓSTICO DA BIBLIOTECA DO INSTITUTO DE HIGIENE E MEDICINA TROPICAL (IHMT): UM ESTUDO DE CASO DE ACERVO DOS ANAIS

Author

Caldeira, Paulo, Francês, Rita, Silva, Ana, and Sousa, Ana

Abstract

In this art icle, we present the diagnosis project of the Inst ituto de Higiene e Medicina Tropical (IHMT) Library and its collect ion. We selected the main tools of analysis, and the criteria and parameters proposed for the general descript ion and analysis of historical charact er of t he document s, applied in a case st udy of t he “ Anais doIHMT ”. In conclusion we point out some fut ure perspectives which may result from the proposed project ., Anais do Instituto de Higiene e Medicina Tropical, v. 11 (2012): Edição Comemorativa

Published
2018

34. Comparing the Continuous Geboes Score With the Robarts Histopathology Index: Definitions of Histological Remission and Response and their Relation to Faecal Calprotectin Levels

Author

Magro, Fernando, primary, Lopes, Joanne, primary, Borralho, Paula, primary, Lopes, Susana, primary, Coelho, Rosa, primary, Cotter, José, primary, Dias de Castro, Francisca, primary, Tavares de Sousa, Helena, primary, Salgado, Marta, primary, Andrade, Patrícia, primary, Vieira, Ana Isabel, primary, Figueiredo, Pedro, primary, Caldeira, Paulo, primary, Sousa, A, primary, Duarte, Maria A, primary, Ávila, Filipa, primary, Silva, João, primary, Moleiro, Joana, primary, Mendes, Sofia, primary, Giestas, Sílvia, primary, Ministro, Paula, primary, Sousa, Paula, primary, Gonçalves, Raquel, primary, Gonçalves, Bruno, primary, Oliveira, Ana, primary, Chagas, Cristina, primary, Cravo, Marilia, primary, Dias, Cláudia Camila, primary, Afonso, Joana, primary, Portela, Francisco, primary, Santiago, Mafalda, primary, Geboes, Karel, primary, and Carneiro, Fátima, primary

Published
2019
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35. Sexual Quality of Life in Inflammatory Bowel Disease: A Multicenter, National-Level Study

Author

Roseira, Joana, primary, Magro, Fernando, primary, Fernandes, Samuel, primary, Simões, Carolina, primary, Portela, Francisco, primary, Vieira, Ana Isabel, primary, Patita, Marta, primary, Leal, Carina, primary, Lago, Paula, primary, Caldeira, Paulo, primary, Gago, Tânia, primary, Currais, Pedro, primary, Dias, Cláudia Camila, primary, Santiago, Mafalda, primary, Dias, Sandra, primary, and Tavares de Sousa, Helena, primary

Published
2019
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37. Sa1867 – Sexual Quality of Life in Inflammatory Bowel Disease – a Multicentre, National-Level Study

Author

Roseira, Joana, primary, Magro, Fernando, additional, Fernandes, Samuel R., additional, Simões, Carolina, additional, Portela, Francisco, additional, Vieira, Ana, additional, Patita, Marta, additional, Leal, Carina, additional, Lago, Paula M., additional, Caldeira, Paulo, additional, Gago, Tania, additional, Currais, Pedro, additional, Dias, Camila, additional, and Sousa, Helena T., additional

Published
2019
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39. Soluble human Suppression of Tumorigenicity 2 is associated with endoscopic activity in patients with moderate-to-severe ulcerative colitis treated with golimumab

Author

Magro, Fernando, primary, Lopes, Susana, additional, Silva, Marco, additional, Coelho, Rosa, additional, Portela, Francisco, additional, Branquinho, Diogo, additional, Correia, Luís, additional, Fernandes, Samuel, additional, Cravo, Marília, additional, Caldeira, Paulo, additional, Tavares de Sousa, Helena, additional, Patita, Marta, additional, Lago, Paula, additional, Ramos, Jaime, additional, Afonso, Joana, additional, Redondo, Isabel, additional, Machado, Patrícia, additional, Philip, George, additional, Lopes, Joanne, additional, and Carneiro, Fátima, additional

Published
2019
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40. Accuracy of Faecal Calprotectin and Neutrophil Gelatinase B-associated Lipocalin in Evaluating Subclinical Inflammation in UlceRaTIVE Colitis-the ACERTIVE study

Author

Magro, Fernando, Lopes, Susana, Coelho, Rosa, Cotter, Jose, Castro, Francisca Dias, Sousa, Helena Tavares, Salgado, Marta, Andrade, Patricia, Vieira, Ana Isabel, Figueiredo, Pedro, Caldeira, Paulo, Sousa, A., Duarte, Maria A., Avila, Filipa, Silva, Joao, Moleiro, Joana, Mendes, Sofia, Giestas, Silvia, Ministro, Paula, Sousa, Paula, Goncalves, Raquel, Goncalves, Bruno, Oliveira, Ana, Chagas, Cristina, Torres, Joana, Dias, Claudia Camila, Lopes, Joanne, Borralho, Paula, Afonso, Joana, Geboes, Karel, Fatima Carneiro, and Ibd, Portuguese Study Group

Subjects
Male, Pathology, Crohns-disease, Neutrophils, Inflammatory bowel disease, Gastroenterology, chemistry.chemical_compound, Feces, 0302 clinical medicine, Gelatinase, Relapse, Irritable bowel syndrome, General Medicine, Middle Aged, Ulcerative colitis, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Female, medicine.symptom, Bowel-disease, Adult, medicine.medical_specialty, Colon, Remission, Remissão induzida, Histologic inflammation, Asymptomatic, Severity, 03 medical and health sciences, Mesalazine, Lipocalin-2, Colite ulcerosa, Internal medicine, medicine, Humans, Colorectal neoplasia, business.industry, Marker, medicine.disease, Faecal calprotectin, chemistry, Remission induction, Matrix-Metalloproteinase-9 Complex, Colitis, Ulcerative, Risk-factor, Calprotectin, business, Leukocyte L1 Antigen Complex, Biomarkers
Abstract

Background and aims: Mucosal healing and histological remission are different targets for patients with ulcerative colitis, but both rely on an invasive endoscopic procedure. This study aimed to assess faecal calprotectin and neutrophil gelatinase B–associated lipocalin as biomarkers for disease activity in asymptomatic ulcerative colitis patients. Methods: This was a multicentric cross-sectional study including 371 patients, who were classified according to their endoscopic and histological scores. These results were evaluated alongside the faecal levels of both biomarkers. Results: Macroscopic lesions [i.e. endoscopic Mayo score ≥1] were present in 28% of the patients, and 9% had active disease according to fht Ulcerative Colitis Endoscopic Index of Severity. Moreover, 21% presented with histological inflammation according to the Geboes index, whereas 15% and 5% presented with focal and diffuse basal plasmacytosis, respectively. The faecal levels of calprotectin and neutrophil gelatinase B–associated lipocalin were statistically higher for patients with endoscopic lesions and histological activity. A receiver operating characteristic–based analysis revealed that both biomarkers were able to indicate mucosal healing and histological remission with an acceptable probability, and cut-off levels of 150–250 μg/g for faecal calprotectin and 12 μg/g for neutrophil gelatinase B–associated lipocalin were proposed. Conclusions: Faecal calprotectin and neutrophil gelatinase B–associated lipocalin levels are a valuable addition for assessment of disease activity in asymptomatic ulcerative colitis patients. Biological levels of the analysed biomarkers below the proposed thresholds can rule out the presence of macroscopic and microscopic lesions with a probability of 75–93%. However, caution should be applied whenever interpreting positive results, as these biomarkers present consistently low positive predictive values. * Abbreviations: : 5-ASA : 5-aminosalicylic acid or ‘mesalazine' AUC : area under the curve AZT : azathioprine FC : faecal calprotectin IBD : inflammatory bowel disease IBS : irritable bowel syndrome IQR : interquartile range MH : mucosal healing NGAL : neutrophil gelatinase B–associated lipocalin NPV : negative predictive value PPV : positive predictive value ROC : receiver operating characteristic UC : ulcerative colitis UCEIS : Ulcerative Colitis Endoscopic Index of Severity.

Published
2017

42. Comparing the Continuous Geboes Score With the Robarts Histopathology Index: Definitions of Histological Remission and Response and their Relation to Faecal Calprotectin Levels.

Author

Magro, Fernando, Lopes, Joanne, Borralho, Paula, Lopes, Susana, Coelho, Rosa, Cotter, José, Castro, Francisca Dias de, Sousa, Helena Tavares de, Salgado, Marta, Andrade, Patrícia, Vieira, Ana Isabel, Figueiredo, Pedro, Caldeira, Paulo, Sousa, A, Duarte, Maria A, Ávila, Filipa, Silva, João, Moleiro, Joana, Mendes, Sofia, and Giestas, Sílvia

Abstract

Background and Aims The histological status of ulcerative colitis [UC] patients in clinical and endoscopic remission has gained space as an important prognostic marker and a key component of disease monitoring. Our main aims were to compare two histological indexes—the continuous Geboes score [GS] and the Robarts Histopathology index [RHI]—regarding their definitions of histological remission and response, and the ability of faecal calprotectin [FC] levels to discriminate between these statuses. Methods This was an analysis of three prospective cohorts including 422 patients previously enrolled in other studies. Results The two continuous scores [GS and RHI] were shown to be significantly correlated [correlation coefficient of 0.806, p < 0.001] and particularly close regarding their definition of histological response: 95% and 88% of all patients classified as having/not having [respectively] histological response according to RHI also did so according to GS. Moreover, median FC levels in patients with histological response were lower than those in patients without histological response [GS: 73.00 vs 525.00, p < 0.001; RHI: 73.50 vs 510.00, p < 0.001]; a similar trend was observed when FC levels of patients in histological remission were compared to those of patients with histological activity [GS: 76.00 vs 228.00, p < 0.001; RHI: 73.50 vs 467.00, p < 0.001]. FC levels allowed us to exclude the absence of histological remission [according to RHI] and absence of histological response [according to RHI and GS], with negative predictive values varying from 82% to 96%. However, optimization of the FC cut-off to exclude the absence of histological remission, as for the continuous GS, falls within values that resemble those of the healthy population. Conclusion The continuous GS and RHI histological scores are strongly correlated in their definitions of histological response. An absence of histological remission could only be excluded at physiological levels of FC. [ABSTRACT FROM AUTHOR]

Published
2020
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44. Su1801 - Different Histological Indexes for the Assessment of Ulcerative Colitis Activity

Author

Magro, Fernando, primary, Lopes, Joanne D., additional, Borralho, Paula, additional, Lopes, Susana, additional, Coelho, Rosa, additional, Cotter, José, additional, de Castro, Francisca Dias, additional, Sousa, Helena T., additional, Lago, Paula M., additional, Salgado, Marta, additional, Andrade, Patricia, additional, Vieira, Ana, additional, Figueiredo, Pedro, additional, Caldeira, Paulo, additional, Sousa, A, additional, Duarte, Maria A, additional, Ávila, Filipa, additional, da Silva, João Pereira, additional, Moleiro, Joana, additional, Mendes, Sofia, additional, Giestas, Silvia, additional, Ministro, Paula, additional, Sousa, Paula, additional, Gonçalves, Raquel, additional, Gonçalves, Bruno M., additional, Oliveira, Ana Maria, additional, Rosa, Isadora, additional, Rodrigues, Marta, additional, Chagas, Cristina, additional, Torres, Joana, additional, Dias, Camila, additional, Afonso, Joana, additional, Geboes, Karel, additional, and Carneiro, Fatima, additional

Published
2018
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45. Comparison of different histological indexes in the assessment of UC activity and their accuracy regarding endoscopic outcomes and faecal calprotectin levels

Author

Magro, Fernando, primary, Lopes, Joanne, additional, Borralho, Paula, additional, Lopes, Susana, additional, Coelho, Rosa, additional, Cotter, José, additional, Castro, Francisca Dias de, additional, Sousa, Helena Tavares de, additional, Salgado, Marta, additional, Andrade, Patrícia, additional, Vieira, Ana Isabel, additional, Figueiredo, Pedro, additional, Caldeira, Paulo, additional, Sousa, A, additional, Duarte, Maria A, additional, Ávila, Filipa, additional, Silva, João, additional, Moleiro, Joana, additional, Mendes, Sofia, additional, Giestas, Sílvia, additional, Ministro, Paula, additional, Sousa, Paula, additional, Gonçalves, Raquel, additional, Gonçalves, Bruno, additional, Oliveira, Ana, additional, Rosa, Isadora, additional, Rodrigues, Marta, additional, Chagas, Cristina, additional, Dias, Cláudia Camila, additional, Afonso, Joana, additional, Geboes, Karel, additional, and Carneiro, Fátima, additional

Published
2018
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46. Ulcerative colitis: let's talk about extent

Author

Vaz, A., Eusébio, Marta, Antunes, A., Queiros, P., Gago, T., Belo, T., Caldeira, Paulo, and Guerreiro, H.

Abstract

Ulcerative colitis (UC) is a chronic inflammatory disease in which clinical course varies substantially between patients. The extent of the disease is usually pointed out as one of the factors responsible for this variation. With this study, we pretended to evaluate the differences in natural history and pharmacological therapy prescription between left-sided and extended UC.

Published
2016

47. Olmesartan-Induced Enteropathy: An Unusual Cause of Villous Atrophy

Author

Eusébio, Marta, Caldeira, Paulo, Antunes, Artur Gião, Ramos, André, Velasco, Francisco, Cadillá, Jesús, and Guerreiro, Horácio

Subjects
Gastrointestinal Diseases, Atrofia, Angiotensin II Receptor Antagonist/adverse effects, Doenças Gastrointestinais, Atrophy, Antanosistas dos Recetores da Angiotensina II/efeitos adversos
Abstract

We report a case of a 63-year-old-man presenting with chronic diarrhea and weight loss while on olmesartan treatment for hypertension. Investigation showed multiple nutritional deficiencies associated with diffuse intestinal villous atrophy. Serologies for celiac disease were negative and other causes of villous atrophy were excluded. Olmesartan as a precipitant agent was suspected and withdrawn. Clinical improvement occurred in days with no need for other therapeutic measures. Follow-up at three months showed clinical remission and almost complete recovery of intestinal atrophy. Olmesartan is an angiotensin receptor blocker commonly prescribed for the management of hypertension. Spruelike enteropathy associated with this drug is a recently described entity with few cases reported. It presents with chronic diarrhea and intestinal villous atrophy and should be included in its differential diagnosis. This case intends to alert clinicians for the possibility of this event in a patient on treatment with this drug. Apresentamos o caso de um homem de 63 anos com diarreia crónica e perda ponderal. Apresentava hipertensão arterial tratada com olmesartan. A investigação complementar mostrou múltiplos défices nutricionais associados a atrofia vilositária intestinal difusa. As serologias de doença celíaca foram negativas e outras causas de atrofia vilositária foram excluídas. Suspeitou-se do olmesartan como agente precipitante, sendo este suspenso. Observou-se melhoria clínica em dias, sem necessidade de outras medidas terapêuticas. No seguimento, aos 3 meses, constatou-se remissão clínica e recuperação quase completa da atrofia intestinal. O olmesartan é um bloqueador dos recetores da angiotensina, geralmente prescrito no tratamento da hipertensão. A enteropatia “spruelike” associada a este fármaco é uma entidade recentemente descrita, com poucos casos reportados. Manifesta-se por diarreia crónica associada a atrofia vilositária intestinal, devendo ser incluída no seu diagnóstico diferencial. Com este caso pretende-se alertar os clínicos para a possibilidade deste evento em doentes sob tratamento com este fármaco.

Published
2016

48. Clinical performance of an infliximab rapid quantification assay

Author

Magro, Fernando, primary, Afonso, Joana, additional, Lopes, Susana, additional, Coelho, Rosa, additional, Gonçalves, Raquel, additional, Caldeira, Paulo, additional, Lago, Paula, additional, de Sousa, Helena Tavares, additional, Ramos, Jaime, additional, Gonçalves, Ana Rita, additional, Ministro, Paula, additional, Rosa, Isadora, additional, Meira, Tânia, additional, Andrade, Patrícia, additional, Soares, João-Bruno, additional, Carvalho, Diana, additional, Sousa, Paula, additional, Vieira, Ana Isabel, additional, Lopes, Joanne, additional, Dias, Cláudia Camila, additional, Geboes, Karel, additional, and Carneiro, Fátima, additional

Published
2017
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49. Calprotectin and the Magnitude of Antibodies to Infliximab in Clinically-stable Ulcerative Colitis Patients are More Relevant Than Infliximab Trough Levels and Pharmacokinetics for Therapeutic Escalation

Author

Magro, Fernando, primary, Afonso, Joana, additional, Lopes, Susana, additional, Coelho, Rosa, additional, Gonçalves, Raquel, additional, Caldeira, Paulo, additional, Lago, Paula, additional, de Sousa, Helena Tavares, additional, Ramos, Jaime, additional, Gonçalves, Ana Rita, additional, Ministro, Paula, additional, Rosa, Isadora, additional, Vieira, Ana Isabel, additional, Andrade, Patrícia, additional, Soares, João-Bruno, additional, Carvalho, Diana, additional, Sousa, Paula, additional, Meira, Tânia, additional, Lopes, Joanne, additional, Moleiro, Joana, additional, Dias, Cláudia Camila, additional, Falcão, Amílcar, additional, Geboes, Karel, additional, and Carneiro, Fatima, additional

Published
2017
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50. Comparison of different histological indexes in the assessment of UC activity and their accuracy regarding endoscopic outcomes and faecal calprotectin levels.

Author

Magro, Fernando, Lopes, Joanne, Borralho, Paula, Lopes, Susana, Coelho, Rosa, Cotter, José, de Castro, Francisca Dias, de Sousa, Helena Tavares, Salgado, Marta, Andrade, Patrícia, Vieira, Ana Isabel, Figueiredo, Pedro, Caldeira, Paulo, Sousa, A., Duarte, Maria A., Ávila, Filipa, Silva, João, Moleiro, Joana, Mendes, Sofia, and Giestas, Sílvia

Subjects
HYPOKINESIA, TAX assessment
Published
2019
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