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1. Beneath HMGA2 alterations in pleomorphic adenomas: Pathological, immunohistochemical, and molecular insights

Author

Ala-Eddine, C., Aubry, K., Babin, E., Bach, C., Badoual, C., Baglin, A.C., Barry, B., Bastit, V., Baujat, B., Benezery, K., Bensadoun, R.J., Benzerdjeb, N., Bernadach, M., Bertolus, C., Biet, A., Bodmer, D., Boisselier, P., Boulagnon-Rombi, C., Bozec, L., Grayeli, A.Bozorg, Brenet, E., Brugel, L., Calais, G., Calugaru, V., Camby, S., Casiraghi, O., Cassagnau, E., Castain, C., Castelli, J., Ceruse, P., Chabolle, F., Chevalier, D., Choussy, O., Clatot, F., Constans, J.M., Coste, A., Coste, F., Costes, V., Cottier, J.P., Coutte, A., Cristofari, J.P., Cupissol, D., Delgrande, J., Delord, J.P., Devauchelle, B., Digue, L., Dolivet, G., Doré, M., Duflo, S., Dufour, X., Dupin, C., Eker, E., Even, C., Evrard, C., Fabiano, E., Faivre, S., Fakhry, N., Ferrand, F.R., Frandon, J., Franetti, D., de Gabory, L., Galy, C., Garcier, M., Garrel, R., Gauthier, H., Gilain, L., Guihard, S., Guillerm, S., Halimi, C., Hans, S., Herman, P., Houessinon, A., Hourseau, M., Huguet, F., Jadaud, E., Jankowski, R., Jeanne, C., Jegoux, F., Juliéron, M., Kaci, R., Kaminsky, M.-C., de Kermadec, H., Kolb, F., Kreps, S., Laadhari, M., Saint Guily, J. Lacau, Laccoureye, L., Lae, M., Lagarde, F., Lagrange, A., Lallemant, B., Lamuraglia, M., Lang, P., Lapeyre, M., Lapierre, A., Cardon, A.Lasne, Le Tourneau, C., Lefebvre, G., Lefevre, M., Lelonge, Y., Leroy, X., Lesnik, M., Liem, X., Linassier, C., Maingon, P., Majoufre, C., Malard, O., Malouf, G., Marchand, C., Marie, J.-P., Maurina, T., Mauvais, O., Merol, J.-C., Michel, J., Mineur, G., Mirafzal, S., Mirghani, H., Modesto, A., Molinier-Blossier, S., de Monès, E., Morinière, S., Mouawad, F., Moya-Plana, A., Muller, L., Musat, E., Nguyen, F., Noel, G., Obongo-Anga, F.R., Onea, M., Orliac, H., Page, C., Patron, V., Pestre, J., Dang, N. Pham, Philouze, P., Poissonnet, G., Pons, C., Pouliquen, C., J.-M.Prades, Prevost, A., Queiros, C., Rahmani, A., Rambeau, A., Ramin, L., Renard, S., Siegfried, A., Righini, C.A., Rolland, F., Saada, E., Sacino, F., Salas, S., Saroul, N., Schultz, P., Simonaggio, A., Sterkers, O., Strunski, V., Sudaka, A., Xu-Shan, S., Taouachi, R., Tassart, M., Testelin, S., J.Thariat, David, M. Timar, Timochenko, A., Toussaint, B., Coste, E. Uro, Valette, G., Van den Abbele, T., Varoquaux, A., Vauleon, E., Vergez, S., Verillaud, B., Villa, J., Villepelet, A., Volondat, M., Vulquin, N., Wagner, I., Wassef, M., Webert, L., Wong, S., Alsugair, Ziyad, Lépine, Charles, Descotes, Françoise, Lanic, Marie-Delphine, Pissaloux, Daniel, Tirode, Franck, Lopez, Jonathan, Céruse, Philippe, Philouze, Pierre, Fieux, Maxime, Wassef, Michel, Baglin, Anne-Catherine, Mihaela, Onea, Castain, Claire, Sudaka, Anne, Uro-Coste, Emmanuelle, Champagnac, Anne, Costes-Martineau, Valérie, Laé, Marick, and Benzerdjeb, Nazim

Published
2024
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2. Characterization of a Molecularly Distinct Subset of Oncocytic Pleomorphic Adenomas/Myoepitheliomas Harboring Recurrent ZBTB47-AS1: PLAG1 Gene Fusion

Author

Alsugair, Ziyad, Perrot, Jimmy, Descotes, Françoise, Lopez, Jonathan, Champagnac, Anne, Pissaloux, Daniel, Castain, Claire, Onea, Mihaela, Céruse, Philippe, Philouze, Pierre, Lépine, Charles, Lanic, Marie-Delphine, Laé, Marick, Costes-Martineau, Valérie, Benzerdjeb, Nazim, Ala-Eddine, C., Aubry, K., Babin, E., Bach, C., Badoual, C., Baglin, A.C., Barry, B., Bastit, V., Baujat, B., Benezery, K., Bensadoun, R.J., Benzerdjeb, N., Bernadach, M., Bertolus, C., Biet, A., Bodmer, D., Boisselier, P., Boulagnon-Rombi, C., Bozec, L., Grayeli, A. Bozorg, Brenet, E., Brugel, L., Calais, G., Calugaru, V., Camby, S., Casiraghi, O., Cassagnau, E., Castain, C., Castelli, J., Ceruse, P., Chabolle, F., Chevalier, D., Choussy, O., Clatot, F., Constans, J.M., Coste, A., Coste, F., Costes, V., Cottier, J.P., Coutte, A., Cristofari, J.P., Cupissol, D., Delgrande, J., Delord, J.P., Devauchelle, B., Digue, L., Dolivet, G., Doré, M., Duflo, S., Dufour, X., Dupin, C., Eker, E., Even, C., Evrard, C., Fabiano, E., Faivre, S., Fakhry, N., Ferrand, F. R., Frandon, J., Franetti, D., de Gabory, L., Galy, C., Garcier, M., Garrel, R., Gauthier, H., Gilain, L., Guihard, S., Guillerm, S., Halimi, C., Hans, S., Herman, P., Houessinon, A., Hourseau, M., Huguet, F., Jadaud, E., Jankowski, R., Jeanne, C., Jegoux, F., Juliéron, M., Kaci, R., Kaminsky, M.-C., de Kermadec, H., Kolb, F., Kreps, S., Laadhari, M., Saint Guily, J. Lacau, Laccoureye, L., Lae, M., Lagarde, F., Lagrange, A., Lallemant, B., Lamuraglia, M., Lang, P., Lapeyre, M., Lapierre, A., Cardon, A. Lasne, Le Tourneau, C., Lefebvre, G, Lefevre, M., Lelonge, Y., Leroy, X., Lesnik, M., Liem, X., Linassier, C., Maingon, P., Majoufre, C., Malard, O., Malouf, G., Marchand, C., Marie, J.-P., Maurina, T., Mauvais, O., Merol, J.-C., Michel, J., Mineur, G., Mirafzal, S., Mirghani, H., Modesto, A., Molinier-Blossier, S., de Monès, E., Morinière, S., Mouawad, F., Moya-Plana, A, Muller, L., Musat, E., Nguyen, F., Noel, G., Obongo-Anga, F.R., Onea, M., Orliac, H., Page, C., Patron, V., Pestre, J., Dang, N. Pham, Philouze, P., Poissonnet, G., Pons, C., Pouliquen, C., Prades, J.-M., Prevost, A., Queiros, C., Rahmani, A., Rambeau, A., Ramin, L., Renard, S., Righini, C.A., Rolland, F., Saada, E., Sacino, F., Salas, S., Saroul, N., Schultz, P., Simonaggio, A., Sterkers, O., Strunski, V., Sudaka, A., Xu-Shan, S., Taouachi, R., Tassart, M., Testelin, S., Thariat, J., David, M. Timar, Timochenko, A., Toussaint, B., Coste, E. Uro, Valette, G., Van den Abbele, T., Varoquaux, A., Vauleon, E., Vergez, S., Verillaud, B., Villa, J., Villepelet, A., Volondat, M., Vulquin, N., Wagner, I., Wassef, M., Webert, L., and Wong, S.

Published
2024
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4. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group

Author

Lacas, Benjamin, Carmel, Alexandra, Landais, Cécile, Wong, Stuart J, Licitra, Lisa, Tobias, Jeffrey S, Burtness, Barbara, Ghi, Maria Grazia, Cohen, Ezra EW, Grau, Cai, Wolf, Gregory, Hitt, Ricardo, Corvò, Renzo, Budach, Volker, Kumar, Shaleen, Laskar, Sarbani Ghosh, Mazeron, Jean-Jacques, Zhong, Lai-Ping, Dobrowsky, Werner, Ghadjar, Pirus, Fallai, Carlo, Zakotnik, Branko, Sharma, Atul, Bensadoun, René-Jean, Redda, Maria Grazia Ruo, Racadot, Séverine, Fountzilas, George, Brizel, David, Rovea, Paolo, Argiris, Athanassios, Nagy, Zoltán Takácsi, Lee, Ju-Whei, Fortpied, Catherine, Harris, Jonathan, Bourhis, Jean, Aupérin, Anne, Blanchard, Pierre, Pignon, Jean-Pierre, Group, MACH-NC Collaborative, Adelstein, DJ, Alfonsi, M, Belkacemi, Y, Bar-Ad, V, Bernier, J, Bratland, Å, Calais, G, Campbell, B, Caudell, J, Chabaud, S, Chamorey, E, Chaukar, D, Choi, KN, Choussy, O, Collette, L, Cruz, JJ, Dani, C, Dauzier, E, Forastiere, AA, Garaud, P, Gregoire, V, Hackshaw, A, Haddad, E, Haffty, BG, Hansen, A, Hayoz, S, Horiot, JC, Jeremic, B, Karrison, TG, Langendijk, JA, Lapeyre, M, Lartigau, E, Leong, T, Le, QT, Lee, PPY, Lewin, F, Lin, A, Lopes, A, Mehta, S, Moon, J, Moyal, E, Occéan, BV, Olmi, P, Orecchia, R, O'Sullivan, B, Overgaard, J, Petit, C, Quon, H, Sanguineti, G, Satar, T, Simes, J, Simon, C, Sire, C, Staar, S, Stromberger, C, Strojan, P, Temam, S, Thomson, D, Timochenko, A, Torri, V, and Tseroni, V

Subjects
Cancer, Clinical Trials and Supportive Activities, Rare Diseases, Clinical Research, 6.5 Radiotherapy and other non-invasive therapies, Evaluation of treatments and therapeutic interventions, Antineoplastic Combined Chemotherapy Protocols, Carcinoma, Squamous Cell, Chemotherapy, Adjuvant, Head and Neck Neoplasms, Humans, Induction Chemotherapy, Randomized Controlled Trials as Topic, Meta-analysis, Review, Individual Patient Data, Randomised Clinical Trials, Chemotherapy, Radiotherapy, Head and Neck Cancer, MACH-NC Collaborative Group, Other Physical Sciences, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

Background and purposeThe Meta-Analysis of Chemotherapy in squamous cell Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) improved overall survival (OS) in patients without distant metastasis. We report the updated results.Materials and methodsPublished or unpublished randomized trials including patients with non-metastatic carcinoma randomized between 1965 and 2016 and comparing curative loco-regional treatment (LRT) to LRT + CT or adding another timing of CT to LRT + CT (main question), or comparing induction CT + radiotherapy to radiotherapy + concomitant (or alternating) CT (secondary question) were eligible. Individual patient data were collected and combined using a fixed-effect model. OS was the main endpoint.ResultsFor the main question, 101 trials (18951 patients, median follow-up of 6.5 years) were analyzed. For both questions, there were 16 new (2767 patients) and 11 updated trials. Around 90% of the patients had stage III or IV disease. Interaction between treatment effect on OS and the timing of CT was significant (p

Published
2021

6. Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis

Author

Adelstein, D.J., Agarwal, J., Alfonsi, M., Argiris, A., Aupérin, A., Bacigalupo, A., Bar-Ad, V., Bartelink, H., Beadle, B., Belkacemi, Y., Bensadoun, R.J., Bernier, J., Blanchard, P., Bourhis, J., Bratland, Å., Brizel, D., Budach, V., Budach, W., Burtness, B., Calais, G., Campbell, B., Caudell, J., Chabaud, S., Chamorey, E., Chaukar, D., Cheugoua-Zanetsie, M., Cho, K.H., Choussy, O., Cruz Hernandez, J.J., Denham, J.W., Dobrowsky, W., Dominello, M.M, Driessen, C.M.L., Fallai, C., Forastiere, A.A., Fortpied, C., Fountzilas, G., Garaud, P., Garden, A.S., Gery, B., Ghadjar, P., Ghi, M.G., Ghosh Laskar, S., Graff-Cailleaud, P., Grau, C., Gregoire, V., Hackshaw, A., Haddad, E, Haffty, B.G., Hansen, A., Hay, J.H., Hayoz, S., Horiot, J.C., Hitt, R., Jeremic, B., Johansen, J., Jones, C., Julieron, M., Kristensen, C.A., Kumar, S., Lacas, B., Langendijk, J.A., Lapeyre, M., Lartigau, E., Licitra, L., Le, Q.T., Lee, J.W., Lee, P., Lewin, F., Li, Y., Lopes, A., Lotayef, M., Maciejewski, B., Mazeron, J.J., Mehta, S., Michalski, W., Moon, J., Moon, S.H., Moyal, E., Nankivell, M., Nilsson, P., Olmi, P., Orecchia, R., O'Sullivan, B., Overgaard, J., Parmar, M.K.B., Petit, C., Pignon, J.P., Pointreau, Y., Posner, M.R., Poulsen, M.G., Quon, H., Racadot, S., Rosenthal, D.I., Rovea, P., Ruo Redda, M.G., Sanguineti, G., Shenouda, G., Simes, J., Sharma, A., Simon, C., Sire, C., Skladowski, K., Spencer, S., Staar, S., Strojan, P., Stromberger, C., Suwinski, R., Szutkowski, Z., Takácsi-Nagy, Z., Tao, Y.G., Temam, S., Thomson, D., Tobias, J.S., Torres-Saavedra, P., Torri, V., Tripcony, L., Trotti, A., Tseroni, V., van Herpen, C., van Tinteren, H., Vermorken, J., Viegas, C.M.P., Vokes, E.E., Waldron, J., Wernecke, K.D, Widder, J., Wolf, G.T., Wong, S.J., Wu, J.S., Yamazaki, H., Zaktonik, B., Zackrisson, B., Zhong, L.P., Petit, Claire, Lacas, Benjamin, Pignon, Jean-Pierre, Le, Quynh Thu, Grégoire, Vincent, Grau, Cai, Hackshaw, Allan, Zackrisson, Björn, Parmar, Mahesh K B, Lee, Ju-Whei, Ghi, Maria Grazia, Sanguineti, Giuseppe, Temam, Stéphane, Cheugoua-Zanetsie, Maurice, O'Sullivan, Brian, Posner, Marshall R, Vokes, Everett E, Cruz Hernandez, Juan J, Szutkowski, Zbigniew, Lartigau, Eric, Budach, Volker, Suwiński, Rafal, Poulsen, Michael, Kumar, Shaleen, Ghosh Laskar, Sarbani, Mazeron, Jean-Jacques, Jeremic, Branislav, Simes, John, Zhong, Lai-Ping, Overgaard, Jens, Fortpied, Catherine, Torres-Saavedra, Pedro, Bourhis, Jean, Aupérin, Anne, and Blanchard, Pierre

Published
2021
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7. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group

Author

Adelstein, D.J., Alfonsi, M., Belkacemi, Y., Bar-Ad, V., Bernier, J., Bratland, Å., Calais, G., Campbell, B., Caudell, J., Chabaud, S., Chamorey, E., Chaukar, D., Choi, K.N., Choussy, O., Collette, L., Cruz, J.J., Dani, C., Dauzier, E., Forastiere, A.A., Garaud, P., Gregoire, V., Hackshaw, A., Haddad, E., Haffty, B.G., Hansen, A., Hayoz, S., Horiot, J.C., Jeremic, B., Karrison, T.G., Langendijk, J.A., Lapeyre, M., Lartigau, E., Leong, T., Le, Q.T., Lee, P.P.Y., Lewin, F., Lin, A., Lopes, A., Mehta, S., Moon, J., Moyal, E., Occéan, B.V., Olmi, P., Orecchia, R., O'Sullivan, B., Overgaard, J., Petit, C., Quon, H., Sanguineti, G., Satar, T., Simes, J., Simon, C., Sire, C., Staar, S., Stromberger, C., Strojan, P., Temam, S., Thomson, D., Timochenko, A., Torri, V., Tseroni, V., Vermorken, J., Vokes, E.E., Waldron, J., Wernecke, K.D., Widder, J., Zackrisson, B., Lacas, Benjamin, Carmel, Alexandra, Landais, Cécile, Wong, Stuart J., Licitra, Lisa, Tobias, Jeffrey S., Burtness, Barbara, Ghi, Maria Grazia, Cohen, Ezra E.W., Grau, Cai, Wolf, Gregory, Hitt, Ricardo, Corvò, Renzo, Budach, Volker, Kumar, Shaleen, Laskar, Sarbani Ghosh, Mazeron, Jean-Jacques, Zhong, Lai-Ping, Dobrowsky, Werner, Ghadjar, Pirus, Fallai, Carlo, Zakotnik, Branko, Sharma, Atul, Bensadoun, René-Jean, Ruo Redda, Maria Grazia, Racadot, Séverine, Fountzilas, George, Brizel, David, Rovea, Paolo, Argiris, Athanassios, Nagy, Zoltán Takácsi, Lee, Ju-Whei, Fortpied, Catherine, Harris, Jonathan, Bourhis, Jean, Aupérin, Anne, Blanchard, Pierre, and Pignon, Jean-Pierre

Published
2021
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8. Patient Satisfaction with Fentanyl Pectin Nasal Spray in Breakthrough Cancer Pain Management During Radiotherapy for Head and Neck Cancer

Author

Pointreau Y, Bensadoun RJ, Bera G, Sire C, Ruffier A, Janoray G, Calais G, Bollet M, Pinel B, Braniste V, and Amores X

Subjects
patient satisfaction, fentanyl nasal spray, breakthrough pain, radiotherapy, head and neck cancer, Medicine (General), R5-920
Abstract

Yoann Pointreau,1 Rene-Jean Bensadoun,2 Guillaume Bera,3 Christian Sire,3 Amandine Ruffier,4 Guillaume Janoray,4,5 Gilles Calais,4 Marc Bollet,6 Baptiste Pinel,7 Viorica Braniste,8 Xavier Amores8 1Radiotherapy Department, Interregional Cancer Institute (ILC) - Jean Bernard Center, Le Mans, France; 2Radiotherapy Department, High Energy Center, Nice, France; 3Oncology and Radiotherapy Department, Southern Brittany Hospital Group, Lorient, France; 4Oncology and Radiotherapy Department, University Hospital of Tours, Tours, France; 5Oncology and Radiotherapy Department, François Rabelais University, EA 7505, Education Ethique Santé (EES), Tours, France; 6Radiotherapy Department, Hartmann Clinic, Neuilly-sur-Seine, France; 7Oncology and Radiotherapy Department, University Hospital of Poitiers, Poitiers, France; 8Kyowa Kirin Pharma, Neuilly-sur-Seine, FranceCorrespondence: Yoann Pointreau Email y.pointreau@cjb72.orgObjective: The severity of breakthrough cancer pain (BTcP) impacts patients’ quality of life, increases the risk of anxiety and depression, lowers functional capacities, and may lead to poor compliance with cancer treatments. The aim of the current study was to assess, in a real-life setting, patient satisfaction with a fentanyl-pectin-nasal-spray (FPNS) for BTcP management in head and neck (H&N) cancer patients treated by radiotherapy.Materials and Methods: This non-interventional, prospective study was conducted in 92 adult H&N-cancer patients undergoing radiotherapy and who started FPNS treatment for BTcP. Throughout the radiotherapy period, the patients completed self-diaries to assess their BTcP episodes, FPNS use, satisfaction on FPNS efficiency (primary outcome), tolerability and ease of use.Results: Prior to FPNS treatment, 86% of the patients were experiencing ≤ 4 BTcP episodes/day. During the radiotherapy period, the BTcP episodes were treated with a median dose of 100μg of FPNS. Patients were “satisfied/very-satisfied” with the efficiency (73% of assessments), ease of use (87% of assessments) and tolerability (87% of assessments) of FPNS. In total, 27% of patients reported at least one adverse event related to FPNS and 4% of patients discontinued treatment due to adverse events. None of the adverse events were serious. Patient quality of life was maintained throughout the radiotherapy period.Conclusion: This study showed, in a real-life setting, that a clear majority of H&N cancer patients treated with FPNS for BTcP throughout radiotherapy expressed satisfaction with this analgesic treatment.Keywords: patient satisfaction, fentanyl nasal spray, breakthrough pain, radiotherapy, head and neck cancer

Published
2020

9. Oncologic outcomes, prognostic factor analysis and therapeutic algorithm evaluation of head and neck mucosal melanomas in France

Author

Albert, S., Andry, G., Babin, E., Bach, C., Badet, J.-M., Badoual, C., Baglin, A.C., Banal, A., Barry, B., Baudin, E., Baujat, B., Bensadoun, R.J., Bertolus, C., Bessède, J.-P., Blanchard, D., Borel, C., Bozorg-Grayeli, A., Breheret, R., Breton, P., Brugel, L., Calais, G., Casiraghi, O., Cassagnau, E., Castillo, L., Ceruse, P., Chabolle, F., Chevalier, D., Chobaut, J.C., Choussy, O., Cosmidis, A., Coste, A., Costes, V., Crampette, L., Darrouzet, V., Demez, P., Dessi, P., Devauchelle, B., Digue, L., Dolivet, G., Dubrulle, F., Duflo, S., Dufour, X., Even, C., Faivre, S., Fakhry, N., Ferron, C., Floret, F., de Gabory, L., Garrel, R., Geoffrois, L., Gilain, L., Giovanni, A., Girod, A., Guerrier, B., Hans, S., Herman, P., Hofman, P., Housset, M., Jankowski, R., Jegoux, F., Juliéron, M., Kaminsky, M.-C., Kolb, F., Lacau St Guily, J., Laccoureye, L., Lallemant, B., Lang, P., Lartigau, E., Lavieille, J.-P., Lefevre, M., Leroy, X., Malard, O., Massip, F., Mauvais, O., Merol, J.-C., Michel, J., Mom, T., Morinière, S., de Monès, E., Moulin, G., Moya-Plana, A., Noel, G., Poissonnet, G., Prades, J.-M., de Raucourt, D., Reyt, E., Righini, C., Marie Robin, Y., Rolland, F., Ruhin, B., Sarroul, N., Schultz, P., Serrano, E., Sterkers, O., Strunski, V., Sudaka, A., Tassart, M., Testelin, S., Thariat, J., Timochenko, A., Toussaint, B., Uro Coste, E., Valette, G., Van den Abbeele, T., Varoquaux, A., Veillon, F., Vergez, S., Vérillaud, B., Wassef, M., Aupérin, A., Obongo, R., Baglin, A., Ferrand, F.R., Saroul, N., and Janot, F.

Published
2019
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11. Characterization of a Molecularly Distinct Subset of Oncocytic Pleomorphic Adenomas/Myoepitheliomas Harboring Recurrent ZBTB47-AS1::PLAG1Gene Fusion

Author

Alsugair, Ziyad, Perrot, Jimmy, Descotes, Françoise, Lopez, Jonathan, Champagnac, Anne, Pissaloux, Daniel, Castain, Claire, Onea, Mihaela, Céruse, Philippe, Philouze, Pierre, Lépine, Charles, Lanic, Marie-Delphine, Laé, Marick, Costes-Martineau, Valérie, Benzerdjeb, Nazim, Ala-Eddine, C., Aubry, K., Babin, E., Bach, C., Badoual, C., Baglin, A.C., Barry, B., Bastit, V., Baujat, B., Benezery, K., Bensadoun, R.J., Benzerdjeb, N., Bernadach, M., Bertolus, C., Biet, A., Bodmer, D., Boisselier, P., Boulagnon-Rombi, C., Bozec, L., Grayeli, A. Bozorg, Brenet, E., Brugel, L., Calais, G., Calugaru, V., Camby, S., Casiraghi, O., Cassagnau, E., Castain, C., Castelli, J., Ceruse, P., Chabolle, F., Chevalier, D., Choussy, O., Clatot, F., Constans, J.M., Coste, A., Coste, F., Costes, V., Cottier, J.P., Coutte, A., Cristofari, J.P., Cupissol, D., Delgrande, J., Delord, J.P., Devauchelle, B., Digue, L., Dolivet, G., Doré, M., Duflo, S., Dufour, X., Dupin, C., Eker, E., Even, C., Evrard, C., Fabiano, E., Faivre, S., Fakhry, N., Ferrand, F. R., Frandon, J., Franetti, D., de Gabory, L., Galy, C., Garcier, M., Garrel, R., Gauthier, H., Gilain, L., Guihard, S., Guillerm, S., Halimi, C., Hans, S., Herman, P., Houessinon, A., Hourseau, M., Huguet, F., Jadaud, E., Jankowski, R., Jeanne, C., Jegoux, F., Juliéron, M., Kaci, R., Kaminsky, M.-C., de Kermadec, H., Kolb, F., Kreps, S., Laadhari, M., Saint Guily, J. Lacau, Laccoureye, L., Lae, M., Lagarde, F., Lagrange, A., Lallemant, B., Lamuraglia, M., Lang, P., Lapeyre, M., Lapierre, A., Cardon, A. Lasne, Le Tourneau, C., Lefebvre, G, Lefevre, M., Lelonge, Y., Leroy, X., Lesnik, M., Liem, X., Linassier, C., Maingon, P., Majoufre, C., Malard, O., Malouf, G., Marchand, C., Marie, J.-P., Maurina, T., Mauvais, O., Merol, J.-C., Michel, J., Mineur, G., Mirafzal, S., Mirghani, H., Modesto, A., Molinier-Blossier, S., de Monès, E., Morinière, S., Mouawad, F., Moya-Plana, A, Muller, L., Musat, E., Nguyen, F., Noel, G., Obongo-Anga, F.R., Onea, M., Orliac, H., Page, C., Patron, V., Pestre, J., Dang, N. Pham, Philouze, P., Poissonnet, G., Pons, C., Pouliquen, C., Prades, J.-M., Prevost, A., Queiros, C., Rahmani, A., Rambeau, A., Ramin, L., Renard, S., Righini, C.A., Rolland, F., Saada, E., Sacino, F., Salas, S., Saroul, N., Schultz, P., Simonaggio, A., Sterkers, O., Strunski, V., Sudaka, A., Xu-Shan, S., Taouachi, R., Tassart, M., Testelin, S., Thariat, J., David, M. Timar, Timochenko, A., Toussaint, B., Coste, E. Uro, Valette, G., Van den Abbele, T., Varoquaux, A., Vauleon, E., Vergez, S., Verillaud, B., Villa, J., Villepelet, A., Volondat, M., Vulquin, N., Wagner, I., Wassef, M., Webert, L., and Wong, S.

Abstract

Recurrent gene fusions are common in salivary gland tumors including benign tumors, such as pleomorphic adenoma (PA) and myoepithelioma (ME). In cases where chromosomal rearrangement is identified in the pleomorphic adenoma gene 1 (PLAG1)gene, different gene partners are found. Oncocytic metaplasia, characterized by oncocytes with abundant eosinophilic granular cytoplasm and hyperchromatic nuclei, is a well-known phenomenon in salivary gland neoplasms. However, the pure oncocytic variant of PA/ME showed PLAG1gene rearrangements involving various gene partners at the molecular level, without any recurrent fusion being found. Our study includes 20 cases of PA/ME, with 11 females and 9 males. The age of patients ranged from 37 to 96 years, with a median age of 62.8 years. Most tumors originate from the parotid gland. The median size of the tumor was 26.5 mm (range: 13 to 60 mm). Among the 20 cases, 14 were a pure oncocytic variant of PA/ME, whereas 6 cases showed focal oncocytic or oncocytic-like aspects. Molecular studies on 20 cases of PA/ME were conducted. A novel recurrent ZBTB47-AS1::PLAG1fusion was identified in 6 of 12 cases with pure oncocytic metaplasia, whereas the other cases had PLAG1gene fusion with different gene partners. The transcriptomic analysis of the cases harboring ZBTB47-AS1::PLAG1fusion demonstrated that these tumors have a distinct molecular profile from conventional PA/ME. This study reveals a unique subset in the oncocytic PA/ME spectrum characterized by pure oncocytic morphology with larger oncocytic cells and recurrent ZBTB47-AS1::PLAG1fusion. It also highlights the transcriptomic distinctness of salivary gland adenomas with pure oncocytic metaplasia in the spectrum of salivary gland neoplasms. Further studies are needed to better understand the oncocytic variant of PA/ME and to determine the true nature of oncocytic cells in PA/ME.

Published
2024
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21. Évolution des concepts dans les cancers des voies aérodigestives supérieures, sous l’égide de l’Intergroupe ORL (GORTEC, GETTEC, GERCOR)

Author

Thariat, J., Jegoux, F., Pointreau, Y., Fayette, J., Boisselier, P., Blanchard, P., Alfonsi, M., Aupérin, A., Bardet, E., Bensadoun, R.-J., Garaud, P., Geoffrois, L., Graff, P., Guigay, J., Janot, F., Lapeyre, M., Lefebvre, J.-L., Martin, L., Racadot, S., Rolland, F., Sire, C., Tao, Y., Tuchais, C., Chibaudel, B., Girard-Calais, M.-H., Cornely, A., Vintonenko, N., Calais, G., De Raucourt, D., Lacau Saint-Guily, J., and Bourhis, J.

Published
2013
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28. Mucoepidermoid carcinoma of salivary glands: A French Network of Rare Head and Neck Tumors (REFCOR) prospective study of 292 cases

Author

Dahan, Laurie Saloner, primary, Giorgi, Roch, additional, Vergez, Sébastien, additional, Le Taillandier de Gabory, Ludovic, additional, Costes-Martineau, Valérie, additional, Herman, Philippe, additional, Poissonnet, Gilles, additional, Mauvais, Olivier, additional, Malard, Olivier, additional, Garrel, Renaud, additional, Uro-Coste, Emmanuelle, additional, Barry, Béatrix, additional, Bach, Christine, additional, Chevalier, Dominique, additional, Mouawad, Francois, additional, Merol, Jean-Claude, additional, Bastit, Vianney, additional, Thariat, Juliette, additional, Gilain, Laurent, additional, Dufour, Xavier, additional, Righini, Christian-Adrien, additional, Moya-Plana, Antoine, additional, Even, Caroline, additional, Radulesco, Thomas, additional, Michel, Justin, additional, Baujat, Bertrand, additional, Fakhry, Nicolas, additional, Albert, S., additional, Andry, G., additional, Babin, E., additional, Bach, C., additional, Badet, J.-M., additional, Badoual, C., additional, Baglin, A.C., additional, Banal, A., additional, Barry, B., additional, Baudin, E., additional, Baujat, B., additional, Bensadoun, R.J., additional, Bertolus, C., additional, Bessède, J.-P., additional, Blanchard, D., additional, Borel, C., additional, Bozorg-Grayeli, A., additional, Breheret, R., additional, Breton, P., additional, Brugel, L., additional, Calais, G., additional, Casiraghi, O., additional, Cassagnau, E., additional, Castillo, L., additional, Ceruse, P., additional, Chabolle, F., additional, Chevalier, D., additional, Chobaut, J.C., additional, Choussy, O., additional, Cosmidis, A., additional, Coste, A., additional, Costes, V., additional, Crampette, L., additional, Darrouzet, V., additional, Demez, P., additional, Dessi, P., additional, Devauchelle, B., additional, Dolivet, G., additional, Dubrulle, F., additional, Duflo, S., additional, Dufour, X., additional, Faivre, S., additional, Fakhry, N., additional, Ferron, C., additional, Floret, F., additional, de Gabory, L., additional, Garrel, R., additional, Geoffrois, L., additional, Gilain, L., additional, Giovanni, A., additional, Girod, A., additional, Guerrier, B., additional, Hans, S., additional, Herman, P., additional, Hofman, P., additional, Housset, M., additional, Jankowski, R., additional, Jegoux, F., additional, Juliéron, M., additional, Kaminsky, M.-C., additional, Kolb, F., additional, St Guily, J. Lacau, additional, Laccoureye, L., additional, Lallemant, B., additional, Lang, P., additional, Lartigau, E., additional, Lavieille, J.-P., additional, Lefevre, M., additional, Leroy, X., additional, Malard, O., additional, Massip, F., additional, Mauvais, O., additional, Merol, J.-C., additional, Michel, J., additional, Mom, T., additional, Morinière, S., additional, de Monès, E., additional, Moulin, G., additional, Noel, G., additional, Poissonnet, G., additional, Prades, J.-M., additional, Radulesco, T., additional, de Raucourt, D., additional, Reyt, E., additional, Righini, C., additional, Robin, Y. Marie, additional, Rolland, F., additional, Ruhin, B., additional, Sarroul, N., additional, Schultz, P., additional, Serrano, E., additional, Sterkers, O., additional, Strunski, V., additional, Sudaka, A., additional, Tassart, M., additional, Testelin, S., additional, Thariat, J., additional, Timochenko, A., additional, Toussaint, B., additional, Coste, E. Uro, additional, Valette, G., additional, Van den Abbeele, T., additional, Varoquaux, A., additional, Veillon, F., additional, Vergez, S., additional, and Wassef, M., additional

Published
2021
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29. Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis

Author

Petit, Claire, primary, Lacas, Benjamin, additional, Pignon, Jean-Pierre, additional, Le, Quynh Thu, additional, Grégoire, Vincent, additional, Grau, Cai, additional, Hackshaw, Allan, additional, Zackrisson, Björn, additional, Parmar, Mahesh K B, additional, Lee, Ju-Whei, additional, Ghi, Maria Grazia, additional, Sanguineti, Giuseppe, additional, Temam, Stéphane, additional, Cheugoua-Zanetsie, Maurice, additional, O'Sullivan, Brian, additional, Posner, Marshall R, additional, Vokes, Everett E, additional, Cruz Hernandez, Juan J, additional, Szutkowski, Zbigniew, additional, Lartigau, Eric, additional, Budach, Volker, additional, Suwiński, Rafal, additional, Poulsen, Michael, additional, Kumar, Shaleen, additional, Ghosh Laskar, Sarbani, additional, Mazeron, Jean-Jacques, additional, Jeremic, Branislav, additional, Simes, John, additional, Zhong, Lai-Ping, additional, Overgaard, Jens, additional, Fortpied, Catherine, additional, Torres-Saavedra, Pedro, additional, Bourhis, Jean, additional, Aupérin, Anne, additional, Blanchard, Pierre, additional, Adelstein, D.J., additional, Agarwal, J., additional, Alfonsi, M., additional, Argiris, A., additional, Aupérin, A., additional, Bacigalupo, A., additional, Bar-Ad, V., additional, Bartelink, H., additional, Beadle, B., additional, Belkacemi, Y., additional, Bensadoun, R.J., additional, Bernier, J., additional, Blanchard, P., additional, Bourhis, J., additional, Bratland, Å., additional, Brizel, D., additional, Budach, V., additional, Budach, W., additional, Burtness, B., additional, Calais, G., additional, Campbell, B., additional, Caudell, J., additional, Chabaud, S., additional, Chamorey, E., additional, Chaukar, D., additional, Cheugoua-Zanetsie, M., additional, Cho, K.H., additional, Choussy, O., additional, Cruz Hernandez, J.J., additional, Denham, J.W., additional, Dobrowsky, W., additional, Dominello, M.M, additional, Driessen, C.M.L., additional, Fallai, C., additional, Forastiere, A.A., additional, Fortpied, C., additional, Fountzilas, G., additional, Garaud, P., additional, Garden, A.S., additional, Gery, B., additional, Ghadjar, P., additional, Ghi, M.G., additional, Ghosh Laskar, S., additional, Graff-Cailleaud, P., additional, Grau, C., additional, Gregoire, V., additional, Hackshaw, A., additional, Haddad, E, additional, Haffty, B.G., additional, Hansen, A., additional, Hay, J.H., additional, Hayoz, S., additional, Horiot, J.C., additional, Hitt, R., additional, Jeremic, B., additional, Johansen, J., additional, Jones, C., additional, Julieron, M., additional, Kristensen, C.A., additional, Kumar, S., additional, Lacas, B., additional, Langendijk, J.A., additional, Lapeyre, M., additional, Lartigau, E., additional, Licitra, L., additional, Le, Q.T., additional, Lee, J.W., additional, Lee, P., additional, Lewin, F., additional, Li, Y., additional, Lopes, A., additional, Lotayef, M., additional, Maciejewski, B., additional, Mazeron, J.J., additional, Mehta, S., additional, Michalski, W., additional, Moon, J., additional, Moon, S.H., additional, Moyal, E., additional, Nankivell, M., additional, Nilsson, P., additional, Olmi, P., additional, Orecchia, R., additional, O'Sullivan, B., additional, Overgaard, J., additional, Parmar, M.K.B., additional, Petit, C., additional, Pignon, J.P., additional, Pointreau, Y., additional, Posner, M.R., additional, Poulsen, M.G., additional, Quon, H., additional, Racadot, S., additional, Rosenthal, D.I., additional, Rovea, P., additional, Ruo Redda, M.G., additional, Sanguineti, G., additional, Shenouda, G., additional, Simes, J., additional, Sharma, A., additional, Simon, C., additional, Sire, C., additional, Skladowski, K., additional, Spencer, S., additional, Staar, S., additional, Strojan, P., additional, Stromberger, C., additional, Suwinski, R., additional, Szutkowski, Z., additional, Takácsi-Nagy, Z., additional, Tao, Y.G., additional, Temam, S., additional, Thomson, D., additional, Tobias, J.S., additional, Torres-Saavedra, P., additional, Torri, V., additional, Tripcony, L., additional, Trotti, A., additional, Tseroni, V., additional, van Herpen, C., additional, van Tinteren, H., additional, Vermorken, J., additional, Viegas, C.M.P., additional, Vokes, E.E., additional, Waldron, J., additional, Wernecke, K.D, additional, Widder, J., additional, Wolf, G.T., additional, Wong, S.J., additional, Wu, J.S., additional, Yamazaki, H., additional, Zaktonik, B., additional, Zackrisson, B., additional, and Zhong, L.P., additional

Published
2021
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30. Short-term androgen deprivation therapy and high-dose radiotherapy in intermediate- and high-risk localized prostate cancer: Results from the GETUG 14 randomized phase III trial

Author

Demogeot, N., Sargos, P., Sahki, N., Guérif, S., De Crevoisier, R., Calais, G., Hannoun Levi, J.M., Bouche, G., Hennequin, C., Cretin, J., Belkacemi, Y., Khalifa, J., Azria, D., Grandgirard, A., Pommier, P., Simon, J.M., Leger, C., Beckendorf, V., Dubray, B., and Supiot, S.

Abstract

Few studies compared short-term androgen deprivation (STADT) with high-dose radiotherapy (STADT-RT) versus high dose radiotherapy (RT) alone in localized prostate cancer.

Published
2024
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31. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group

Author

Lacas, Benjamin, primary, Carmel, Alexandra, additional, Landais, Cécile, additional, Wong, Stuart J., additional, Licitra, Lisa, additional, Tobias, Jeffrey S., additional, Burtness, Barbara, additional, Ghi, Maria Grazia, additional, Cohen, Ezra E.W., additional, Grau, Cai, additional, Wolf, Gregory, additional, Hitt, Ricardo, additional, Corvò, Renzo, additional, Budach, Volker, additional, Kumar, Shaleen, additional, Laskar, Sarbani Ghosh, additional, Mazeron, Jean-Jacques, additional, Zhong, Lai-Ping, additional, Dobrowsky, Werner, additional, Ghadjar, Pirus, additional, Fallai, Carlo, additional, Zakotnik, Branko, additional, Sharma, Atul, additional, Bensadoun, René-Jean, additional, Ruo Redda, Maria Grazia, additional, Racadot, Séverine, additional, Fountzilas, George, additional, Brizel, David, additional, Rovea, Paolo, additional, Argiris, Athanassios, additional, Nagy, Zoltán Takácsi, additional, Lee, Ju-Whei, additional, Fortpied, Catherine, additional, Harris, Jonathan, additional, Bourhis, Jean, additional, Aupérin, Anne, additional, Blanchard, Pierre, additional, Pignon, Jean-Pierre, additional, Adelstein, D.J., additional, Alfonsi, M., additional, Belkacemi, Y., additional, Bar-Ad, V., additional, Bernier, J., additional, Bratland, Å., additional, Calais, G., additional, Campbell, B., additional, Caudell, J., additional, Chabaud, S., additional, Chamorey, E., additional, Chaukar, D., additional, Choi, K.N., additional, Choussy, O., additional, Collette, L., additional, Cruz, J.J., additional, Dani, C., additional, Dauzier, E., additional, Forastiere, A.A., additional, Garaud, P., additional, Gregoire, V., additional, Hackshaw, A., additional, Haddad, E., additional, Haffty, B.G., additional, Hansen, A., additional, Hayoz, S., additional, Horiot, J.C., additional, Jeremic, B., additional, Karrison, T.G., additional, Langendijk, J.A., additional, Lapeyre, M., additional, Lartigau, E., additional, Leong, T., additional, Le, Q.T., additional, Lee, P.P.Y., additional, Lewin, F., additional, Lin, A., additional, Lopes, A., additional, Mehta, S., additional, Moon, J., additional, Moyal, E., additional, Occéan, B.V., additional, Olmi, P., additional, Orecchia, R., additional, O'Sullivan, B., additional, Overgaard, J., additional, Petit, C., additional, Quon, H., additional, Sanguineti, G., additional, Satar, T., additional, Simes, J., additional, Simon, C., additional, Sire, C., additional, Staar, S., additional, Stromberger, C., additional, Strojan, P., additional, Temam, S., additional, Thomson, D., additional, Timochenko, A., additional, Torri, V., additional, Tseroni, V., additional, Vermorken, J., additional, Vokes, E.E., additional, Waldron, J., additional, Wernecke, K.D., additional, Widder, J., additional, and Zackrisson, B., additional

Published
2021
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34. Proposition de sélection et délimitation des volumes cibles microscopiques péritumoraux dans les cancers de la cavité buccale et de l'oropharynx (aires ganglionnaires exclues)

Author

Lapeyre, M., Henrot, P., Alfonsi, M., Bardet, E., Bensadoun, R.J., Dolivet, G., Favrel, V., Gallocher, O., Giraud, P., Graff, P., Guerif, S., Lagarde, P., Lartigau, E., Marchesi, V., Pommier, P., Rives, M., Tortochaux, J., Toussaint, B., Verrelle, P., Bourhis, J., and Calais, G.

Published
2005
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36. Gait speed, cognition and falls in people living with mild-to-moderate Alzheimer disease: data from NILVAD

Author

Dyer, A. H., Murphy, C., Lawlor, B., Kennelly, S. P., Segurado, R., Olde Rikkert, M. G. M., Howard, R., Pasquier, F., Börjesson-Hanson, A., Tsolaki, M., Lucca, U., Molloy, D. William, Coen, R., Riepe, M. W., Kálmán, J., Kenny, R. A., Cregg, F., O'Dwyer, S., Walsh, C., Adams, J., Banzi, R., Breuilh, L., Daly, L., Hendrix, S., Aisen, P., Gaynor, S., Sheikhi, A., Taekema, D. G., Verhey, F. R., Nemni, R., Nobili, F., Franceschi, M., Frisoni, G., Zanetti, O., Konsta, A., Anastasios, O., Nenopoulou, S., Tsolaki-Tagaraki, F., Pakaski, M., Dereeper, O., Sayette, V. D. L., Sénéchal, O., Lavenu, I., Devendeville, A., Calais, G., Crawford, F., Mullan, M., Aalten, P., Berglund, M. A., Claassen, J. A., De Heus, R. A., De Jong, D. L. K., Godefroy, O., Hutchinson, S., Ioannou, A., Jonsson, M., Kent, A., Kern, J., Nemtsas, P., Panidou, M.-K., Abdullah, L., Paris, D., Santoso, A. M., van Spijker, G. J., Spiliotou, M., Thomoglou, G., Wallin, A., and NILVAD Study Group

Subjects
medicine.medical_specialty, Alzheimer disease, Cognition, Dementia, Falls, Alzheimer`s disease Donders Center for Medical Neuroscience [Radboudumc 1], medicine.medical_treatment, Falls in older adults, lcsh:Geriatrics, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, medicine, Humans, Cognitive Dysfunction, 030212 general & internal medicine, Gait, Aged, Rehabilitation, business.industry, medicine.disease, Gait speed, Walking Speed, lcsh:RC952-954.6, Cross-Sectional Studies, Cohort, Accidental Falls, Geriatrics and Gerontology, Alzheimer's disease, business, human activities, 030217 neurology & neurosurgery, Research Article
Abstract

Background Previous evidence suggests that slower gait speed is longitudinally associated with cognitive impairment, dementia and falls in older adults. Despite this, the longitudinal relationship between gait speed, cognition and falls in those with a diagnosis of dementia remains poorly explored. We sought to assess this longitudinal relationship in a cohort of older adults with mild to-moderate Alzheimer Disease (AD). Methods Analysis of data from NILVAD, an 18-month randomised-controlled trial of Nilvadipine in mild to moderate AD. We examined: (i) the cross-sectional (baseline) association between slow gait speed and cognitive function, (ii) the relationship between baseline slow gait speed and cognitive function at 18 months (Alzheimer Disease Assessment Scale, Cognitive Subsection: ADAS-Cog), (iii) the relationship between baseline cognitive function and incident slow gait speed at 18 months and finally (iv) the relationship of baseline slow gait speed and incident falls over the study period. Results Overall, one-tenth (10.03%, N = 37/369) of participants with mild-to-moderate AD met criteria for slow gait speed at baseline and a further 14.09% (N = 52/369) developed incident slow gait speed at 18 months. At baseline, there was a significant association between poorer cognition and slow gait speed (OR 1.05, 95% CI 1.01–1.09, p = 0.025). Whilst there was no association between baseline slow gait speed and change in ADAS-Cog score at 18 months, a greater cognitive severity at baseline predicted incident slow gait speed over 18 months (OR 1.04, 1.01–1.08, p = 0.011). Further, slow gait speed at baseline was associated with a significant risk of incident falls over the study period, which persisted after covariate adjustment (IRR 3.48, 2.05–5.92, p Conclusions Poorer baseline cognition was associated with both baseline and incident slow gait speed. Slow gait speed was associated with a significantly increased risk of falls over the study period. Our study adds further evidence to the complex relationship between gait and cognition in this vulnerable group and highlights increased falls risk in older adults with AD and slow gait speed. Trial registration Secondary analysis of the NILVAD trial (Clincaltrials.gov NCT02017340; EudraCT number 2012–002764-27). First registered: 20/12/2013.

Published
2020

44. Oncologic outcomes, prognostic factor analysis and therapeutic algorithm evaluation of head and neck mucosal melanomas in France

Author

Moya-Plana, A., primary, Aupérin, A., additional, Obongo, R., additional, Baglin, A., additional, Ferrand, F.R., additional, Baujat, B., additional, Saroul, N., additional, Casiraghi, O., additional, Vergez, S., additional, Herman, P., additional, Janot, F., additional, Thariat, J., additional, Vérillaud, B., additional, de Gabory, L., additional, Albert, S., additional, Andry, G., additional, Babin, E., additional, Bach, C., additional, Badet, J.-M., additional, Badoual, C., additional, Baglin, A.C., additional, Banal, A., additional, Barry, B., additional, Baudin, E., additional, Bensadoun, R.J., additional, Bertolus, C., additional, Bessède, J.-P., additional, Blanchard, D., additional, Borel, C., additional, Bozorg-Grayeli, A., additional, Breheret, R., additional, Breton, P., additional, Brugel, L., additional, Calais, G., additional, Cassagnau, E., additional, Castillo, L., additional, Ceruse, P., additional, Chabolle, F., additional, Chevalier, D., additional, Chobaut, J.C., additional, Choussy, O., additional, Cosmidis, A., additional, Coste, A., additional, Costes, V., additional, Crampette, L., additional, Darrouzet, V., additional, Demez, P., additional, Dessi, P., additional, Devauchelle, B., additional, Digue, L., additional, Dolivet, G., additional, Dubrulle, F., additional, Duflo, S., additional, Dufour, X., additional, Even, C., additional, Faivre, S., additional, Fakhry, N., additional, Ferron, C., additional, Floret, F., additional, Garrel, R., additional, Geoffrois, L., additional, Gilain, L., additional, Giovanni, A., additional, Girod, A., additional, Guerrier, B., additional, Hans, S., additional, Hofman, P., additional, Housset, M., additional, Jankowski, R., additional, Jegoux, F., additional, Juliéron, M., additional, Kaminsky, M.-C., additional, Kolb, F., additional, Lacau St Guily, J., additional, Laccoureye, L., additional, Lallemant, B., additional, Lang, P., additional, Lartigau, E., additional, Lavieille, J.-P., additional, Lefevre, M., additional, Leroy, X., additional, Malard, O., additional, Massip, F., additional, Mauvais, O., additional, Merol, J.-C., additional, Michel, J., additional, Mom, T., additional, Morinière, S., additional, de Monès, E., additional, Moulin, G., additional, Moya-Plana, A., additional, Noel, G., additional, Poissonnet, G., additional, Prades, J.-M., additional, de Raucourt, D., additional, Reyt, E., additional, Righini, C., additional, Marie Robin, Y., additional, Rolland, F., additional, Ruhin, B., additional, Sarroul, N., additional, Schultz, P., additional, Serrano, E., additional, Sterkers, O., additional, Strunski, V., additional, Sudaka, A., additional, Tassart, M., additional, Testelin, S., additional, Timochenko, A., additional, Toussaint, B., additional, Uro Coste, E., additional, Valette, G., additional, Van den Abbeele, T., additional, Varoquaux, A., additional, Veillon, F., additional, and Wassef, M., additional

Published
2019
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45. Étude de phase 1 d’escalade de dose d’irradiation avec modulation d’intensité et boost intégré simultané dans la chimioradiothérapie pelvienne des cancers du bas et moyen rectum métastatiques synchrones

Author

Lizée, T., primary, Seegers, V., additional, Blanchecotte, J., additional, Rio, E., additional, Capitain, O., additional, Guérin-Meyer, V., additional, Legouté, F., additional, Gonzalez-Moya, A., additional, Calais, G., additional, Autret, D., additional, Mahé, M.-A., additional, and Paumier, A., additional

Published
2019
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47. PO-0841 Salvage SBRT for local prostate cancer recurrence after radiotherapy: a GETUG retrospective study

Author

Martinage, G., primary, Janoray, G., additional, Rojas, D.P., additional, Zerini, D., additional, Goupy, F., additional, De Crevoisier, R., additional, Bogart, E., additional, Calais, G., additional, Toledano, A., additional, Chauveinc, L., additional, Scher, N., additional, Bondiau, P.Y., additional, Hannoun-Levi, J.M., additional, Silva, M., additional, Meyer, E., additional, Nickers, P., additional, Lacornerie, T., additional, Lartigau, E., additional, Jereczek-Fossa, B.A., additional, and Pasquier, D., additional

Published
2019
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49. Results of a phase III prospective, randomised trial, comparing mitoxantrone and vinorelbine (MV) in combination with standard FAC/FEC in front-line therapy of metastatic breast cancer

Author

Namer, M, Soler-Michel, P, Turpin, F, Chinet-Charrot, P, de Gislain, C, Pouillart, P, Delozier, T, Luporsi, E, Etienne, P.L, Schraub, S, Eymard, J.C, Serin, D, Ganem, G, Calais, G, Maillart, P, Colin, P, Trillet-Lenoir, V, Prevost, G, Tigaud, D, Clavère, P, Marti, P, Romieu, G, and Wendling, J.L

Published
2001
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