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Your search keyword '"Caitlin D’Amico"' showing total 2 results
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2 results on '"Caitlin D’Amico"'

1. The biological mechanism involved in anticancer properties of amniotic membrane

Author

Ameneh Jafari, Hassan Niknejad, Mostafa Rezaei-Tavirani, Hakimeh Zali, and Caitlin D’Amico

Subjects
Amniotic membrane, cancer, apoptosis, angiogenesis., Other systems of medicine, RZ201-999, Internal medicine, RC31-1245
Abstract

The main role of amniotic membrane (AM), or amnion, is to protect the fetus from drying out and create an appropriate environment for its growth. AM is also a suitable candidate for the treatment of various diseases due to its unique characteristics. In recent years, a new line of research has focused on the anticancer properties of amnion and its potential use in cancer treatment. The in vitro and in vivo studies indicate the anti-proliferative and proapoptotic activities, as well as the angioregulatory and immunomodulatory properties of the amniotic membrane. However, the exact mechanism and molecular basis of these anticancer effects of AM are not fully elucidated. This paper presents an overview of the latest findings and knowledge about the anticancer effects of AM and its underlying molecular mechanisms, which is crucial for the application of amnion in cancer therapy.

Published
2020
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2. Preparation and characterization of polylactic-co-glycolic acid/insulin nanoparticles encapsulated in methacrylate coated gelatin with sustained release for specific medical applications

Author

Seyed Mohammad Davachi, Elham Akhavan Farid, Farhood Najafi, Maryam Tabatabaei Hakim, Alireza Abbaspourrad, Shahrouz Taranejoo, Javad Seyfi, Caitlin D’Amico, Iman Hejazi, and Mohamad Pezeshki-Modaress

Subjects
Drug, food.ingredient, media_common.quotation_subject, medicine.medical_treatment, 0206 medical engineering, Biomedical Engineering, Biophysics, Nanoparticle, Bioengineering, Capsules, 02 engineering and technology, Methacrylate, Gelatin, Biomaterials, Plga nanoparticles, chemistry.chemical_compound, food, Polylactic Acid-Polyglycolic Acid Copolymer, medicine, Insulin, Glycolic acid, media_common, Drug Carriers, Chemistry, Temperature, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, 020601 biomedical engineering, Chemical engineering, Delayed-Action Preparations, Drug release, Methacrylates, Nanoparticles, 0210 nano-technology
Abstract

This study aimed to examine the possibility of using insulin orally with gelatin encapsulation to enhance the usefulness of the drug and increase the lifespan of insulin in the body using polylactic-co-glycolic acid (PLGA) nanoparticles alongside gelatin encapsulation. In this regard, PLGA was synthesized

Published
2020

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