Search

Your search keyword '"Cai, Xing-jun"' showing total 12 results
Start Over Author "Cai, Xing-jun"
12 results on '"Cai, Xing-jun"'

1. A Double-Blind Randomized Placebo-Controlled Phase 3 Trial of Tobramycin Inhalation Solution in Adults With Bronchiectasis With Pseudomonas aeruginosa Infection

Author

Guan, Wei-jie, Xu, Jin-fu, Luo, Hong, Xu, Xing-xiang, Song, Yuan-lin, Ma, Wan-li, Liang, Zong-an, Liu, Xue-dong, Zhang, Guo-jun, Zhang, Xiao-ju, Li, Rong-kai, Zhu, Shu-yang, Zhang, Yi-jie, Cai, Xing-jun, Wei, Li-ping, Tian, Dong-bo, Zhao, Hui, Chen, Ping-yan, Qu, Jie-ming, and Zhong, Nan-shan

Published
2023
Full Text
View/download PDF

3. sj-pdf-1-ini-10.1177_17534259211034221 - Supplemental material for Long non-coding RNA ZFAS1 alleviates sepsis-induced myocardial injury via target miR-34b-5p/SIRT1

Author

Chen, Dan-Dan, Wang, Hong-Wu, and Cai, Xing-Jun

Subjects
animal structures, viruses, FOS: Clinical medicine, 110306 Endocrinology
Abstract

Supplemental material, sj-pdf-1-ini-10.1177_17534259211034221 for Long non-coding RNA ZFAS1 alleviates sepsis-induced myocardial injury via target miR-34b-5p/SIRT1 by Dan-Dan Chen, Hong-Wu Wang and Xing-Jun Cai in Innate Immunity

Published
2021
Full Text
View/download PDF

9. Three new ester glycosides with cytotoxic activity from the seeds of Caesalpinia sappan.

Author

Wang, Min, Tan, Juan, Chen, Jun, Xie, Tian, Lin, Liang-Mo, Zhong, Li-Li, Cai, Xing-Jun, and Wu, Qiong-Shi

Subjects
CAESALPINIA, GLYCOSIDES, SEEDS, ESTERS, CELL lines, MARINE natural products
Abstract

Three new ester glycosides, named as Caesateroside A (1), Caesateroside B (2) and Caesateroside C (3) were obtained from the seeds of Caesalpinia sappan. The new structures of compounds 1-3 were elucidated by analyzing their 1 D NMR, 2 D NMR and HR-ESI-MS spectra. Compounds 1-3 showed weak-moderate cytotoxicity against Hela and HepG-2 human cancer cell lines. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

10. Ferroptosis is involved in alcohol-induced cell death in vivoand in vitro

Author

Liu, Chun-Yu, Wang, Min, Yu, Hong-Min, Han, Fang-Xuan, Wu, Qiong-Shi, Cai, Xing-Jun, Kurihara, Hiroshi, Chen, Yong-Xing, Li, Yi-Fang, and He, Rong-Rong

Abstract

ABSTRACTA critical pathogenic factor in the development of lethal liver failure is cell death induced by the accumulation of lipid reactive oxygen species. In this study, we discovered and illuminated a new mechanism that led to alcoholic liver disease via ferroptosis, an iron-dependent regulated cell death. Study in vitroshowed that both necroptosis inhibitor and ferroptosis inhibitors performed significantly protective effect on alcohol-induced cell death, while apoptosis inhibitor and autophagy inhibitor had no such effect. Our data also indicated that alcohol caused the accumulation of lipid peroxides and the mRNA expression of prostaglandin-endoperoxide synthase 2, reduced the protein expression of the specific light-chain subunit of the cystine/glutamate antiporter and glutathione peroxidase 4. Importantly, ferrostatin-1 significantly ameliorated liver injury that was induced by overdosed alcohol both in vitroand in vivo. These findings highlight that targeting ferroptosis serves as a hepatoprotective strategy for alcoholic liver disease treatment.

Published
2020
Full Text
View/download PDF

12. A Double-Blind Randomized Placebo-Controlled Phase 3 Trial of Tobramycin Inhalation Solution in Adults With Bronchiectasis With Pseudomonas aeruginosaInfection

Author

Guan, Wei-jie, Xu, Jin-fu, Luo, Hong, Xu, Xing-xiang, Song, Yuan-lin, Ma, Wan-li, Liang, Zong-an, Liu, Xue-dong, Zhang, Guo-jun, Zhang, Xiao-ju, Li, Rong-kai, Zhu, Shu-yang, Zhang, Yi-jie, Cai, Xing-jun, Wei, Li-ping, Tian, Dong-bo, Zhao, Hui, Chen, Ping-yan, Qu, Jie-ming, and Zhong, Nan-shan

Abstract

Few large-scale studies have demonstrated the efficacy of tobramycin nebulization in bronchiectasis. We evaluated the efficacy and safety of nebulized tobramycin inhalation solution (TIS) in adults with bronchiectasis with Pseudomonas aeruginosainfection.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results