Search

Your search keyword '"Cahill, Megan E."' showing total 22 results
Start Over Author "Cahill, Megan E."
22 results on '"Cahill, Megan E."'

3. Coding

Author

Jackman, Claire C., Dyer, Katherine H., Sharp, Jessica L., Miller-Cahill, Megan E., Fountain, Stephen B., Dunphy-Lelii, Sarah, Section editor, Vonk, Jennifer, editor, and Shackelford, Todd K., editor

Published
2022
Full Text
View/download PDF

6. Coding

Author

Jackman, Claire C., primary, Dyer, Katherine H., additional, Sharp, Jessica L., additional, Miller-Cahill, Megan E., additional, and Fountain, Stephen B., additional

Published
2020
Full Text
View/download PDF

8. Evaluation of Public Health Contact Tracing for Mpox Among Gay, Bisexual, and Other Men Who Have Sex With Men—10 US Jurisdictions, May 17–July 31, 2022

Author

Cope, Anna Barry, primary, Kirkcaldy, Robert D., additional, Weidle, Paul J., additional, Jackson, David A., additional, Laramee, Nicholas, additional, Weber, Robyn, additional, Rowse, Julia, additional, Mangla, Anil, additional, Fox, Brian, additional, Saunders, Katharine E., additional, Taniguchi, Kristen, additional, Usagawa, Lauren, additional, Cahill, Megan E., additional, Harrington, Pauline, additional, Ricketts, Erin K., additional, Harbi, Khalil, additional, Malec, Lenka, additional, Templin, Tingting Gu, additional, Drociuk, Dan, additional, Hannibal, Terri, additional, Klos, Rachel, additional, and Bernstein, Kyle T., additional

Published
2023
Full Text
View/download PDF

10. Analytical Approaches to Uncover Genetic Associations for Rare Outcomes: Lessons from West Nile Neuroinvasive Disease

Author

Cahill, Megan E. and Montgomery, Ruth R.

Subjects
Incidence, Humans, West Nile virus, Article, West Nile Fever
Abstract

West Nile viral infection causes severe neuroinvasive disease in less than one percent of infected humans. There are no targeted therapeutics for this serious and potentially fatal disease, and to date no vaccine has been approved for humans. With climate change expected to result in rising incidence of West Nile and other related vector-borne viral infections, there is an increasing need to identify those at risk for serious disease and potential leads for therapeutic and vaccine development. Genetic variation, particularly in genes whose products are either directly or indirectly connected to immune response to infections, is a critical avenue of investigation to identify those at higher risk of clinically apparent West Nile infection. Given the small percent of infections that progress to severe disease and the relatively low numbers of reported infections, it is challenging to conduct well-powered studies to identify genetic factors associated with more severe outcomes. In this chapter, we outline several approaches with the objective to take full advantage of all available data in order to identify genetic factors which lead to increased risk of severe West Nile neuroinvasive disease. These methods are generalizable to other conditions with limited cohort size and rare outcomes.

Published
2022
Full Text
View/download PDF

12. West Nile Virus Seroprevalence, Connecticut, USA, 2000-014

Author

Cahill, Megan E., Yao, Yi, Nock, David, Armstrong, Philip M., Andreadis, Theodore G., Diuk-Wasser, Maria A., and Montgomery, Ruth R.

Subjects
West Nile fever -- Health aspects, Medical research -- Health aspects, Infection -- Health aspects, Health
Abstract

Since the 1999 emergence of West Nile virus (WNV) in North America, >43,000 cases of disease and 1,884 deaths have been reported (1); overall infections are estimated at [approximately equal [...]

Published
2017

13. Additional file 1 of A new method for exploring gene–gene and gene–environment interactions in GWAS with tree ensemble methods and SHAP values

Author

Johnsen, Pål V., Riemer-Sørensen, Signe, DeWan, Andrew Thomas, Cahill, Megan E., and Langaas, Mette

Subjects
ComputerApplications_COMPUTERSINOTHERSYSTEMS
Abstract

Additional file 1. Supplementary materials providing technical details about quality control of genetic data, theory, implementation as well as figures.

Published
2021
Full Text
View/download PDF

17. Single cell immune profiling of dengue virus patients reveals intact immune responses to Zika virus with enrichment of innate immune signatures

Author

Zhao, Yujiao, primary, Amodio, Matthew, additional, Vander Wyk, Brent, additional, Gerritsen, Bram, additional, Kumar, Mahesh M., additional, van Dijk, David, additional, Moon, Kevin, additional, Wang, Xiaomei, additional, Malawista, Anna, additional, Richards, Monique M., additional, Cahill, Megan E., additional, Desai, Anita, additional, Sivadasan, Jayasree, additional, Venkataswamy, Manjunatha M., additional, Ravi, Vasanthapuram, additional, Fikrig, Erol, additional, Kumar, Priti, additional, Kleinstein, Steven H., additional, Krishnaswamy, Smita, additional, and Montgomery, Ruth R., additional

Published
2020
Full Text
View/download PDF

22. Analytical Approaches to Uncover Genetic Associations for Rare Outcomes: Lessons from West Nile Neuroinvasive Disease.

Author

Cahill ME and Montgomery RR

Subjects
Humans, Incidence, West Nile Fever complications, West Nile virus genetics
Abstract

West Nile viral infection causes severe neuroinvasive disease in less than 1% of infected humans. There are no targeted therapeutics for this serious and potentially fatal disease, and to date no vaccine has been approved for humans. With climate change expected to result in rising incidence of West Nile and other related vector-borne viral infections, there is an increasing need to identify those at risk for serious disease and potential leads for therapeutic and vaccine development. Genetic variation, particularly in genes whose products are either directly or indirectly connected to immune response to infections, is a critical avenue of investigation to identify those at higher risk of clinically apparent West Nile infection. Given the small percent of infections that progress to severe disease and the relatively low numbers of reported infections, it is challenging to conduct well-powered studies to identify genetic factors associated with more severe outcomes. In this chapter, we outline several approaches with the objective to take full advantage of all available data in order to identify genetic factors which lead to increased risk of severe West Nile neuroinvasive disease. These methods are generalizable to other conditions with limited cohort size and rare outcomes., (© 2023. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.)

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results