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4. A Neurorobotics Approach to Behaviour Selection based on Human Activity Recognition

Author

Ranieri, Caetano M., Moioli, Renan C., Vargas, Patricia A., and Romero, Roseli A. F.

Subjects
Computer Science - Robotics, Computer Science - Artificial Intelligence
Abstract

Behaviour selection has been an active research topic for robotics, in particular in the field of human-robot interaction. For a robot to interact effectively and autonomously with humans, the coupling between techniques for human activity recognition, based on sensing information, and robot behaviour selection, based on decision-making mechanisms, is of paramount importance. However, most approaches to date consist of deterministic associations between the recognised activities and the robot behaviours, neglecting the uncertainty inherent to sequential predictions in real-time applications. In this paper, we address this gap by presenting a neurorobotics approach based on computational models that resemble neurophysiological aspects of living beings. This neurorobotics approach was compared to a non-bioinspired, heuristics-based approach. To evaluate both approaches, a robot simulation is developed, in which a mobile robot has to accomplish tasks according to the activity being performed by the inhabitant of an intelligent home. The outcomes of each approach were evaluated according to the number of correct outcomes provided by the robot. Results revealed that the neurorobotics approach is advantageous, especially considering the computational models based on more complex animals., Comment: This preprint has not undergone peer review or any post-submission improvements or corrections. The Version of Record of this article is published in Cognitive Neurodynamics (2022), and is available online at https://doi.org/10.1007/s11571-022-09886-z

Published
2021
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5. A Data-Driven Biophysical Computational Model of Parkinson's Disease based on Marmoset Monkeys

Author

Ranieri, Caetano M., Pimentel, Jhielson M., Romano, Marcelo R., Elias, Leonardo A., Romero, Roseli A. F., Lones, Michael A., Araujo, Mariana F. P., Vargas, Patricia A., and Moioli, Renan C.

Subjects
Quantitative Biology - Neurons and Cognition, Computer Science - Artificial Intelligence
Abstract

In this work we propose a new biophysical computational model of brain regions relevant to Parkinson's Disease based on local field potential data collected from the brain of marmoset monkeys. Parkinson's disease is a neurodegenerative disorder, linked to the death of dopaminergic neurons at the substantia nigra pars compacta, which affects the normal dynamics of the basal ganglia-thalamus-cortex neuronal circuit of the brain. Although there are multiple mechanisms underlying the disease, a complete description of those mechanisms and molecular pathogenesis are still missing, and there is still no cure. To address this gap, computational models that resemble neurobiological aspects found in animal models have been proposed. In our model, we performed a data-driven approach in which a set of biologically constrained parameters is optimised using differential evolution. Evolved models successfully resembled single-neuron mean firing rates and spectral signatures of local field potentials from healthy and parkinsonian marmoset brain data. As far as we are concerned, this is the first computational model of Parkinson's Disease based on simultaneous electrophysiological recordings from seven brain regions of Marmoset monkeys. Results show that the proposed model could facilitate the investigation of the mechanisms of PD and support the development of techniques that can indicate new therapies. It could also be applied to other computational neuroscience problems in which biological data could be used to fit multi-scale models of brain circuits.

Published
2021
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8. Unlocking the microbiome

Author

Rosana BR Ferreira and L Caetano M Antunes

Subjects
microbiome, fruit flies, D. melanogaster, yeast, bacteria, Medicine, Science, Biology (General), QH301-705.5
Abstract

Individual species of bacteria and yeast present in the food of wild fruit flies work together to provide the nutrients needed for larval growth.

Published
2023
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13. Polymyxin Resistance in Clinical Isolates of K. pneumoniae in Brazil: Update on Molecular Mechanisms, Clonal Dissemination and Relationship With KPC-Producing Strains

Author

Orlando C. Conceição-Neto, Bianca Santos da Costa, Leilane da Silva Pontes, Melise Chaves Silveira, Lívia Helena Justo-da-Silva, Ivson Cassiano de Oliveira Santos, Camila Bastos Tavares Teixeira, Thamirys Rachel Tavares e Oliveira, Fernanda Stephens Hermes, Teca Calcagno Galvão, L. Caetano M. Antunes, Cláudio Marcos Rocha-de-Souza, and Ana P. D. Carvalho-Assef

Subjects
polymyxin resistance, Klebsiella pneumoniae, antibiotic resistance, mcr gene, PhoPQ and PmrAB, Microbiology, QR1-502
Abstract

In Brazil, the production of KPC-type carbapenemases in Enterobacteriales is endemic, leading to widespread use of polymyxins. In the present study, 502 Klebsiella pneumoniae isolates were evaluated for resistance to polymyxins, their genetic determinants and clonality, in addition to the presence of carbapenem resistance genes and evaluation of antimicrobial resistance. Resistance to colistin (polymyxin E) was evaluated through initial selection on EMB agar containing 4% colistin sulfate, followed by Minimal Inhibitory Concentration (MIC) determination by broth microdilution. The susceptibility to 17 antimicrobials was assessed by disk diffusion. The presence of blaKPC, blaNDM and blaOXA-48-like carbapenemases was investigated by phenotypic methods and conventional PCR. Molecular typing was performed by PFGE and MLST. Allelic variants of the mcr gene were screened by PCR and chromosomal mutations in the pmrA, pmrB, phoP, phoQ and mgrB genes were investigated by sequencing. Our work showed a colistin resistance frequency of 29.5% (n = 148/502) in K. pneumoniae isolates. Colistin MICs from 4 to >128 µg/mL were identified (MIC50 = 64 µg/mL; MIC90 >128 µg/mL). All isolates were considered MDR, with the lowest resistance rates observed for amikacin (34.4%), and 19.6% of the isolates were resistant to all tested antimicrobials. The blaKPC gene was identified in 77% of the isolates, in consonance with the high rate of resistance to polymyxins related to its use as a therapeutic alternative. Through XbaI-PFGE, 51 pulsotypes were identified. MLST showed 21 STs, with ST437, ST258 and ST11 (CC11) being the most prevalent, and two new STs were determined: ST4868 and ST4869. The mcr-1 gene was identified in 3 K. pneumoniae isolates. Missense mutations in chromosomal genes were identified, as well as insertion sequences in mgrB. Furthermore, the identification of chromosomal mutations in K. pneumoniae isolates belonging from CC11 ensures its success as a high-risk epidemic clone in Brazil and worldwide.

Published
2022
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16. A Data-Driven Biophysical Computational Model of Parkinson’s Disease Based on Marmoset Monkeys

Author

Caetano M. Ranieri, Jhielson M. Pimentel, Marcelo R. Romano, Leonardo A. Elias, Roseli A. F. Romero, Michael A. Lones, Mariana F. P. Araujo, Patricia A. Vargas, and Renan C. Moioli

Subjects
Basal ganglia, brain modelling, computational modelling, evolutionary computation, neural engineering, Parkinson’s disease, Electrical engineering. Electronics. Nuclear engineering, TK1-9971
Abstract

In this work we propose a new biophysical computational model of brain regions relevant to Parkinson’s Disease (PD) based on local field potential data collected from the brain of marmoset monkeys. PD is a neurodegenerative disorder, linked to the death of dopaminergic neurons at the substantia nigra pars compacta, which affects the normal dynamics of the basal ganglia-thalamus-cortex (BG-T-C) neuronal circuit of the brain. Although there are multiple mechanisms underlying the disease, a complete description of those mechanisms and molecular pathogenesis are still missing, and there is still no cure. To address this gap, computational models that resemble neurobiological aspects found in animal models have been proposed. In our model, we performed a data-driven approach in which a set of biologically constrained parameters is optimised using differential evolution. Evolved models successfully resembled spectral signatures of local field potentials and single-neuron mean firing rates from healthy and parkinsonian marmoset brain data. This is the first computational model of PD based on simultaneous electrophysiological recordings from seven brain regions of Marmoset monkeys. Results indicate that the proposed model may facilitate the investigation of the mechanisms of PD and eventually support the development of new therapies. The DE method could also be applied to other computational neuroscience problems in which biological data is used to fit multi-scale models of brain circuits.

Published
2021
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17. The Global Biogeochemical Cycle of the Rare Earth Elements.

Author

Hatje, V., Schijf, J., Johannesson, K. H., Andrade, R., Caetano, M., Brito, P., Haley, B. A., Lagarde, M., and Jeandel, C.

Subjects
RARE earth metals, BIOGEOCHEMICAL cycles, NEODYMIUM isotopes, ANTHROPOGENIC effects on nature, CARBON cycle, YTTRIUM, RARE earth oxides, NEODYMIUM
Abstract

To improve our understanding and guide future studies and applications, we review the biogeochemistry of the rare earth elements (REE). The REEs, which form a chemically uniform group due to their nearly identical physicochemical properties, include the lanthanide series elements plus scandium (Sc) and yttrium (Y). These elements, in conjunction with the neodymium isotopes, are powerful tools for understanding key oceanic, terrestrial, biological and even anthropogenic processes. Furthermore, their unique properties render them essential for various technological processes and products. Here, we delve into the characteristics of REE biogeochemistry and discuss normalization procedures and REE anomalies. We also examine the aqueous speciation of REEs, contributing to a better understanding of their behavior in aquatic settings, including the role of neodymium isotopes. We then focus on their environmental distribution, fractionation, and controlling processes in different environmental systems across the land‐ocean continuum. In addition, we analyze sinks, sources, and the mobility of REEs, providing insights into their behavior in these environments. We further investigate the sources of anthropogenic REEs and their bioavailability, bioaccumulation, and transfer along food webs. We also explore the potential effects of climate change on the cycling, mobility and bioavailability of REEs, underlining the importance of current research in this evolving field. In summary, we provide a comprehensive review of REE behavior in the environment, from their properties and roles to their distribution and anthropogenic impacts, offering valuable insights and pinpointing key knowledge gaps. Key Points: Rare earth elements (REE) are powerful tracers of both natural and anthropogenic processes within terrestrial and ocean environmentsREE are controlled by absorption, adsorption/desorption, co‐precipitation, remineralization, and particle dissolutionREE are technology‐critical metals with broad applications in the future low‐carbon global economy [ABSTRACT FROM AUTHOR]

Published
2024
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24. Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease

Author

Jhielson M. Pimentel, Renan C. Moioli, Mariana F. P. de Araujo, Caetano M. Ranieri, Roseli A. F. Romero, Frank Broz, and Patricia A. Vargas

Subjects
neurorobotics, basal ganglia, motor control, Parkinson's disease, motor cortex, robot controller, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

In this work, we present the first steps toward the creation of a new neurorobotics model of Parkinson's Disease (PD) that embeds, for the first time in a real robot, a well-established computational model of PD. PD mostly affects the modulation of movement in humans. The number of people suffering from this neurodegenerative disease is set to double in the next 15 years and there is still no cure. With the new model we were capable to further explore the dynamics of the disease using a humanoid robot. Results show that the embedded model under both conditions, healthy and parkinsonian, was capable of performing a simple behavioural task with different levels of motor disturbance. We believe that this neurorobotics model is a stepping stone to the development of more sophisticated models that could eventually test and inform new PD therapies and help to reduce and replace animals in research.

Published
2021
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26. Integrated analysis of ethionamide resistance loci in Mycobacterium tuberculosis clinical isolates

Author

da Silva, Duanne Alves, Ferreira, Nicole Victor, Rego, Amanda Mendes, Barbosa, Pamela Chrystina Pinto, Machado, Rodrigo Fernandes, Pimentel, Alessandra, dos Reis, Lusiano Motta, de Pina, Lucindo Cardoso, Redner, Paulo, Caldas, Paulo Cesar de Souza, Fandinho-Montes, Fátima Cristina Onofre, Borga, Liamar, Leite, Suzanne Pereira, da Rocha, Jorge Luiz, Bastos, Leonardo Soares, Ramos, Jesus Pais, Degrave, Wim Maurits, Antunes, L. Caetano M., and Galvão, Teca Calcagno

Published
2018
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28. Lifelong Exposure to a Low-Dose of the Glyphosate-Based Herbicide RoundUp® Causes Intestinal Damage, Gut Dysbiosis, and Behavioral Changes in Mice

Author

Ingrid Del Castilo, Arthur S. Neumann, Felipe S. Lemos, Marco A. De Bastiani, Felipe L. Oliveira, Eduardo R. Zimmer, Amanda M. Rêgo, Cristiane C. P. Hardoim, Luis Caetano M. Antunes, Flávio A. Lara, Claudia P. Figueiredo, and Julia R. Clarke

Subjects
herbicide, repetitive behavior, social impairment, neurodevelopmental diseases, gut–brain axis, inflammation, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract

RoundUp® (RUp) is a comercial formulation containing glyphosate (N-(phosphono-methyl) glycine), and is the world’s leading wide-spectrum herbicide used in agriculture. Supporters of the broad use of glyphosate-based herbicides (GBH) claim they are innocuous to humans, since the active compound acts on the inhibition of enzymes which are absent in human cells. However, the neurotoxic effects of GBH have already been shown in many animal models. Further, these formulations were shown to disrupt the microbiome of different species. Here, we investigated the effects of a lifelong exposure to low doses of the GBH-RUp on the gut environment, including morphological and microbiome changes. We also aimed to determine whether exposure to GBH-RUp could harm the developing brain and lead to behavioral changes in adult mice. To this end, animals were exposed to GBH-RUp in drinking water from pregnancy to adulthood. GBH-RUp-exposed mice had no changes in cognitive function, but developed impaired social behavior and increased repetitive behavior. GBH-Rup-exposed mice also showed an activation of phagocytic cells (Iba-1–positive) in the cortical brain tissue. GBH-RUp exposure caused increased mucus production and the infiltration of plama cells (CD138-positive), with a reduction in phagocytic cells. Long-term exposure to GBH-RUp also induced changes in intestinal integrity, as demonstrated by the altered expression of tight junction effector proteins (ZO-1 and ZO-2) and a change in the distribution of syndecan-1 proteoglycan. The herbicide also led to changes in the gut microbiome composition, which is also crucial for the establishment of the intestinal barrier. Altogether, our findings suggest that long-term GBH-RUp exposure leads to morphological and functional changes in the gut, which correlate with behavioral changes that are similar to those observed in patients with neurodevelopmental disorders.

Published
2022
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29. Bioactive small molecules produced by the human gut microbiome modulate Vibrio cholerae sessile and planktonic lifestyles

Author

Heidi Pauer, Felipe Lopes Teixeira, Avery V. Robinson, Thiago E. Parente, Marília A. F. De Melo, Leandro A. Lobo, Regina M. C. P. Domingues, Emma Allen-Vercoe, Rosana B. R. Ferreira, and Luis Caetano M. Antunes

Subjects
gut metabolome, antivirulence, bioactive small molecules, vibrio cholerae, microbial signaling, motility, Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Humans live in symbiosis with a diverse community of microorganisms, which has evolved to carry out many specific tasks that benefit the host, including protection against invading pathogens. Within the chemical diversity of the gastrointestinal tract, small molecules likely constitute chemical cues for the communication between the microbiota and pathogens. Therefore, we sought to investigate if molecules produced by the human gut microbiota show biological activity against the human pathogen Vibrio cholerae. To probe the effects of the gut metabolome on V. cholerae, we investigated its response to small-molecule extracts from human feces, from a complex bacterial community cultivated in vitro, and from culture supernatants of Enterocloster citroniae, Bacteroides thetaiotaomicron, and Bacteroides vulgatus. Using RNA sequencing, we determined the impact of the human gut metabolome on V. cholerae global gene expression. Among the genes downregulated in the presence of the fecal extract, the most overrepresented functional category was cell motility, which accounted for 39% of repressed genes. Repression of V. cholerae motility by the fecal extract was confirmed phenotypically, and E. citroniae extracts reproduced this phenotype. A complex in vitro microbial community led to increased motility, as did extracts from B. vulgatus, a species present in this community. Accordingly, mucin penetration was also repressed by fecal and E. citroniae extracts, suggesting that the phenotypes observed may have implications for host colonization. Together with previous studies, this work shows that small molecules from the gut metabolome may have a widespread, significant impact on microbe–microbe interactions established in the gut environment.

Published
2021
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30. Use of Alkaline Solid Wastes from Kraft Pulp and Paper Mills, Dregs and Grits in Cement Production

Author

Torres, C. M. M. E., Pedroti, L. G., Silva, C. M., Fernandes, W. E. H., Viana, N. G., Martins, R. O. G., Lima, G. E. S., Sathler, L. M., Andrade, I. K. R., Caetano, M. A., Ikhmayies, Shadia, editor, Li, Bowen, editor, Carpenter, John S., editor, Li, JIan, editor, Hwang, Jiann-Yang, editor, Monteiro, Sergio Neves, editor, Firrao, Donato, editor, Zhang, Mingming, editor, Peng, Zhiwei, editor, Escobedo-Diaz, Juan P., editor, Bai, Chenguang, editor, Kalay, Yunus Eren, editor, Goswami, Ramasis, editor, and Kim, Jeongguk, editor

Published
2017
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32. Evaluation of Physico-Chemical Properties When Adding Boiler Ashes to Mortar

Author

Caetano, M. A., Martins, R. O. G., de Lima, G. E. S., Araújo, A. I., Pedroti, L. G., Rezende, A. A. P., Alvarenga, R. C. S. S., Ikhmayies, Shadia Jamil, editor, Li, Bowen, editor, Carpenter, John S., editor, Hwang, Jiann-Yang, editor, Monteiro, Sergio Neves, editor, Li, Jian, editor, Firrao, Donato, editor, Zhang, Mingming, editor, Peng, Zhiwei, editor, Escobedo-Diaz, Juan P., editor, and Bai, Chenguang, editor

Published
2016
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33. Spatial distribution and temporal trends of butyltin compounds (TBT, DBT & MBT) in short sediment cores of the SW Portuguese Shelf (western Iberian Margin, NE Atlantic)

Author

Mil-Homens, M., Almeida, C. M. R., Dias, S., Soares, W., van Gaever, P., de Stigter, H., Santos, M.N., Santana, A., Freitas, M., Abrantes, F., Caetano, M., Mil-Homens, M., Almeida, C. M. R., Dias, S., Soares, W., van Gaever, P., de Stigter, H., Santos, M.N., Santana, A., Freitas, M., Abrantes, F., and Caetano, M.

Abstract

Spatial patterns and temporal trends of the butyltin compounds tributyltin (TBT), dibutyltin (DBT), and monobutyltin (MBT) were investigated in a set of sediment samples collected along the SW Portuguese continental shelf. This region did not reach the Good Environmental Status (GES) in accordance with the Marine Strategy Framework Directive (MSFD) during a first evaluation carried out in 2012. Overall, MBT and DBT were the predominant organotin species detected, but high concentrations of TBT were found in and around disposal sites for dredge sludge derived from the dredging in navigation channels, harbours, and shipyard facilities of the Tagus and Sado estuaries. Although Portuguese regulations for monitoring sediment quality in relation to dredging activities consider only PAH, PCB and HCB, they also dictate that other organic contaminants such as butyltin compounds (BTs) should be monitored if suspicion of high values exists, but no action limits are defined for these (MAOTDR, 2007). Without action limits, the monitoring recommendation given in the regulations is not put into practice. Considering their toxicity, BT derivates should be integrated in the legislation, because they represent an environmental threat in the relocation of dredged material, especially when derived from harbour and shipyards areas. Based on this study, we recommend giving more attention to the amounts and impacts of BTs in sediments at dredged material disposal sites (DMDS) and their surroundings. Or even better, in order to be more efficient, monitoring should be done at the source of the dredged materials and not at the sink. In case it is not done, the monitoring of concentrations of TBT (and other BTs) in sediments and organisms, including imposex studies, at all Portuguese sites for disposal of dredged material receiving slightly to strongly contaminated dredged material must be developed.

Published
2023

40. Polymyxin Resistance in Clinical Isolates of K. pneumoniae in Brazil: Update on Molecular Mechanisms, Clonal Dissemination and Relationship With KPC-Producing Strains

Author

Conceição-Neto, Orlando C., da Costa, Bianca Santos, Pontes, Leilane da Silva, Silveira, Melise Chaves, Justo-da-Silva, Lívia Helena, de Oliveira Santos, Ivson Cassiano, Teixeira, Camila Bastos Tavares, Tavares e Oliveira, Thamirys Rachel, Hermes, Fernanda Stephens, Galvão, Teca Calcagno, Antunes, L. Caetano M., Rocha-de-Souza, Cláudio Marcos, and Carvalho-Assef, Ana P. D.

Subjects
Microbiology (medical), Infectious Diseases, Immunology, Microbiology
Abstract

In Brazil, the production of KPC-type carbapenemases in Enterobacteriales is endemic, leading to widespread use of polymyxins. In the present study, 502 Klebsiella pneumoniae isolates were evaluated for resistance to polymyxins, their genetic determinants and clonality, in addition to the presence of carbapenem resistance genes and evaluation of antimicrobial resistance. Resistance to colistin (polymyxin E) was evaluated through initial selection on EMB agar containing 4% colistin sulfate, followed by Minimal Inhibitory Concentration (MIC) determination by broth microdilution. The susceptibility to 17 antimicrobials was assessed by disk diffusion. The presence of blaKPC, blaNDM and blaOXA-48-like carbapenemases was investigated by phenotypic methods and conventional PCR. Molecular typing was performed by PFGE and MLST. Allelic variants of the mcr gene were screened by PCR and chromosomal mutations in the pmrA, pmrB, phoP, phoQ and mgrB genes were investigated by sequencing. Our work showed a colistin resistance frequency of 29.5% (n = 148/502) in K. pneumoniae isolates. Colistin MICs from 4 to >128 µg/mL were identified (MIC50 = 64 µg/mL; MIC90 >128 µg/mL). All isolates were considered MDR, with the lowest resistance rates observed for amikacin (34.4%), and 19.6% of the isolates were resistant to all tested antimicrobials. The blaKPC gene was identified in 77% of the isolates, in consonance with the high rate of resistance to polymyxins related to its use as a therapeutic alternative. Through XbaI-PFGE, 51 pulsotypes were identified. MLST showed 21 STs, with ST437, ST258 and ST11 (CC11) being the most prevalent, and two new STs were determined: ST4868 and ST4869. The mcr-1 gene was identified in 3 K. pneumoniae isolates. Missense mutations in chromosomal genes were identified, as well as insertion sequences in mgrB. Furthermore, the identification of chromosomal mutations in K. pneumoniae isolates belonging from CC11 ensures its success as a high-risk epidemic clone in Brazil and worldwide.

Published
2022

44. Unlocking the microbiome: Individual species of bacteria and yeast present in the food of wild fruit flies work together to provide the nutrients needed for larval growth.

Author

FERREIRA, ROSANA B. R. and ANTUNES, L. CAETANO M.

Subjects
*FRUIT flies, *WILD foods, *SPECIES, *YEAST, *ACETOBACTER
Abstract

A recent study published in eLife explores the role of individual species of bacteria and yeast in the microbiome of wild fruit flies. The researchers found that these microbes work together to provide the necessary nutrients for larval growth. By studying fruit flies, which have less complex microbiomes than humans, the researchers were able to identify specific microbial species that contribute to larval development. This research sheds light on the complex interactions between diet, microbes, and host microbiomes, and could have implications for manipulating microbiomes for various benefits, such as improving human health or altering the behavior of pollinating insects. [Extracted from the article]

Published
2023
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45. List of Contributors

Author

Abbas, B., primary, Abreu, A., additional, Adams, R., additional, Adolfsson-Erici, M., additional, Afonso, A., additional, Afonso-Olivares, C., additional, Agirbas, E., additional, Aguiló, J.M., additional, Airoldi, L., additional, Aksoy, H., additional, Albentosa, M., additional, Alcaro, L., additional, Aliani, S., additional, Al-Maslamani, I., additional, Alomar, C., additional, Altin, D., additional, Álvarez, E., additional, Amaral-Zettler, L.A., additional, Amato, E., additional, Anderson, A., additional, Andrady, A.L., additional, Andrius, G., additional, Angel, D., additional, Ariese, F., additional, Arp, H.P., additional, Asensio, M., additional, Assidqi, K., additional, Avio, C.G., additional, Aytan, U., additional, Bahri, T., additional, Baini, M., additional, Bakir, A., additional, Ball, H., additional, Baranyi, C., additional, Barboza, L.G.A., additional, Barg, U., additional, Bargelloni, L., additional, Barras, H., additional, Barrera, C., additional, Barria, P., additional, Barrows, A., additional, Barth, A., additional, Batel, A., additional, Baztan, J., additional, Baztan, P., additional, Beiras, R., additional, Benedetti, M., additional, Berber, A.A., additional, Berber, N., additional, Bergmann, M., additional, Berlino, M., additional, Berrow, S., additional, Bessa, F., additional, Besseling, E., additional, Beyer, B., additional, Binaglia, M., additional, Bizjak, T., additional, Bjorndal, K.A., additional, Blust, R., additional, Boertien, M., additional, Bolten, A.B., additional, Booth, A.M., additional, Bounoua, B., additional, Bourseau, P., additional, Brahimi, N., additional, Bramini, M., additional, Brennholt, N., additional, Breuninger, E., additional, Bried, J., additional, Broderick, A., additional, Broglio, E., additional, Browne, M.A., additional, Bruzaud, S., additional, Buceta, J., additional, Buchinger, S., additional, Budimir, S., additional, Budzin-ski, H., additional, Butter, E., additional, Cachot, J., additional, Caetano, M., additional, Callaghan, A., additional, Camedda, A., additional, Capella, S., additional, Cardelli, L., additional, Carpentieri, S., additional, Carrasco, A., additional, Carriço, R., additional, Caruso, A., additional, Cassone, A.-L., additional, Castillo, A., additional, Castro, R.O., additional, Catarino, A.I., additional, Cazenave, P.W., additional, Çelik, İ., additional, Cerralbo, P., additional, César, G., additional, Chouinard, O., additional, Chubarenko, I., additional, Chubarenko, I.P., additional, Cicero, A.M., additional, Clarindo, G., additional, Clarke, B., additional, Clérandeau, C., additional, Clüsener-Godt, M., additional, Codina-García, M., additional, Cole, M., additional, Collard, F., additional, Collignon, A., additional, Collins, T., additional, Compa, M., additional, Conan, P., additional, Constant, M., additional, Cordier, M., additional, Courtene-Jones, W., additional, Cousin, X., additional, Covelo, P., additional, Cózar, A., additional, Crichton, E., additional, Crispi, O., additional, Cronin, M., additional, Croot, P.L., additional, Cruz, M.J., additional, d’Errico, G., additional, Dâmaso, C., additional, Das, K., additional, de Alencastro, L.F., additional, de Araujo, F.V., additional, de Boer, J.F., additional, de Lucia, G.A., additional, Debeljak, P., additional, Dehaut, A., additional, Deudero, S., additional, Devrieses, L., additional, Di Vito, S., additional, Díaz, A., additional, Donohue, J., additional, Doumenq, P., additional, Doyle, T.K., additional, Dris, R., additional, Druon, J.-N., additional, Duarte, C.M., additional, Duflos, G., additional, Dumontier, M., additional, Duncan, E., additional, Dussud, C., additional, Eckerlebe, A., additional, Egelkraut-Holtus, M., additional, Eidsvoll, D.P., additional, Ek, C., additional, Elena, S., additional, Elineau, A., additional, Enevoldsen, H., additional, Eppe, G., additional, Eriksen, M., additional, Ernsteins, R., additional, Espino, M., additional, Estévez-Calvar, N., additional, Ewins, C., additional, Fabre, P., additional, Faimali, M., additional, Fattorini, D., additional, Faure, F., additional, Ferrando, S., additional, Ferreira, J.C., additional, Ferreira-da-Costa, M., additional, Fileman, E., additional, Fischer, M., additional, Fortunato, A.B., additional, Fossi, M.C., additional, Foulon, V., additional, Frank, A., additional, Frenzel, M., additional, Frère, L., additional, Frias, J.P.G.L., additional, Frick, H., additional, Froneman, P.W., additional, Gabet, V.M., additional, Gabrielsen, G.W., additional, Gago, J., additional, Gajst, T., additional, Galgani, F., additional, Gallinari, M., additional, Galloway, T.S., additional, Gamarro, E.G., additional, Gambardella, C., additional, Garaventa, F., additional, Garcia, S., additional, Garrabou, J., additional, Garrido, P., additional, Gary, S.F., additional, Gasperi, J., additional, Gaze, W., additional, Geertz, T., additional, Gelado-Caballero, M.D., additional, George, M., additional, Gercken, J., additional, Gerdts, G., additional, Ghiglione, J.-F., additional, Gies, E., additional, Gilbert, B., additional, Giménez, L., additional, Glassom, D., additional, Glockzin, M., additional, Godley, B., additional, Goede, K., additional, Goksøyr, A., additional, Gómez, M., additional, Gómez-Parra, A., additional, González-Marco, D., additional, González-Solís, J., additional, Gorbi, S., additional, Gorokhova, E., additional, Gorsky, G., additional, Gosch, M., additional, Grose, J., additional, Guebitz, G.M., additional, Guedes-Alonso, R., additional, Guijarro, B., additional, Guilhermino, L., additional, Gundry, T., additional, Gutow, L., additional, Haave, M., additional, Haeckel, M., additional, Haernvall, K., additional, Hajbane, S., additional, Hamann, M., additional, Hämer, J., additional, Hamm, T., additional, Hansen, B.H., additional, Hardesty, B.D., additional, Harth, B., additional, Hartikainen, S., additional, Hassellöv, M., additional, Hatzky, S., additional, Healy, M.G., additional, Hégaret, H., additional, Henry, T.B., additional, Hermabessiere, L., additional, Hernández-Brito, J.J., additional, Hernandez-Gonzalez, A., additional, Hernandez-Milian, G., additional, Hernd, G., additional, Herrera, A., additional, Herring, C., additional, Herzke, D., additional, Heussner, S., additional, Hidalgo-Ruz, V., additional, Himber, C., additional, Holland, M., additional, Hong, N.-H., additional, Horton, A.A., additional, Horvat, P., additional, Huck, T., additional, Huhn, M., additional, Huvet, A., additional, Iglesias, M., additional, Igor, C., additional, Isachenko, I.A., additional, Ivar do Sul, J-A., additional, Jahnke, A., additional, Janis, B., additional, Janis, K., additional, Janis, U., additional, Jemec, A., additional, Jiménez, J.C., additional, Johnsen, H., additional, Jorgensen, B., additional, Jørgensen, J.H., additional, Jörundsdóttir, H., additional, Jung, Y.-J., additional, Kedzierski, M., additional, Keiter, S., additional, Kershaw, P., additional, Kerhervé, P., additional, Kesy, K., additional, Khan, F., additional, Khatmullina, L.I., additional, Kirby, J., additional, Kiriakoulakis, K., additional, Klein, R., additional, Klunderud, T., additional, Knudsen, C.M.H., additional, Knudsen, T.B., additional, Kochleus, C., additional, Koelmans, A.A., additional, Kögel, T., additional, Koistinen, A., additional, Kopke, K., additional, Korez, Š., additional, Kowalski, N., additional, Kreikemeyer, B., additional, Kroon, F., additional, Krumpen, T., additional, Krzan, A., additional, Kržan, A., additional, Labrenz, M., additional, Lacroix, C., additional, Ladirat, L., additional, Laforsch, C., additional, Lagarde, F., additional, Lahive, E., additional, Lambert, C., additional, Lapucci, C., additional, Lattin, G., additional, Law, K.L., additional, Le Roux, F., additional, Le Souef, K., additional, Le Tilly, V., additional, Lebreton, L., additional, Leemans, E., additional, Lehtiniemi, M., additional, Lenz, M., 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additional, Martins, H.R., additional, Matiddi, M., additional, Maximenko, N., additional, Mazlum, R., additional, Mcadam, R., additional, Mcknight, L., additional, McNeal, A.W., additional, Measures, J., additional, Mederos, M.S., additional, Mendoza, J., additional, Meyer, M.S., additional, Miguelez, A., additional, Milan, M., additional, Militão, T., additional, Miller, R.Z., additional, Mino-Vercellio-Verollet, M., additional, Mir, G., additional, Miranda-Urbina, D., additional, Misurale, F., additional, Montesdeoca-Esponda, S., additional, Mora, J., additional, Morgana, S., additional, Moriceau, B., additional, Morin, B., additional, Morley, A., additional, Morrison, L., additional, Murphy, F., additional, Naidoo, T., additional, Näkki, P., additional, Napper, I.E., additional, Narayanaswamy, B.E., additional, Nash, R., additional, Negri, A., additional, Nel, H.A., additional, Nerheim, M.S., additional, Nerland, I.L., additional, Neto, J., additional, Neves, V., additional, Nies, H., additional, Noel, M., additional, Nor, N.H.M., additional, Noren, F., additional, O’ Connell, B., additional, O’ Connor, I., additional, Obbard, J.P., additional, Oberbeckmann, S., additional, Obispo, R., additional, Officer, R., additional, Ogonowski, M., additional, Orbea, A., additional, Ortlieb, M., additional, Osborn, A.M., additional, Ostiategui-Francia, P., additional, Packard, T., additional, Pahl, S., additional, Palatinus, A., additional, Palmqvist, A., additional, Pannetier, P., additional, Panti, C., additional, Parmentier, E., additional, Pasanen, P., additional, Patarnello, T., additional, Pattiaratchi, C., additional, Pauletto, M., additional, Paulus, M., additional, Pavlekovsky, K., additional, Pedersen, H.B., additional, Pedrotti, M.-L., additional, Peeken, I., additional, Peeters, D., additional, Peeters, E., additional, Pellegrini, D., additional, Perales, J.A., additional, Perez, E., additional, Perz, V., additional, Petit, S., additional, Pflieger, M., 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additional, Thomas, K.V., additional, Thompson, R.C., additional, Tinkara, T., additional, Tirelli, V., additional, Tomassetti, P., additional, Toorman, E., additional, Toppe, J., additional, Tornambè, A., additional, Torres, R., additional, Torres-Padrón, M.E., additional, Underwood, A.J., additional, Urbina, M., additional, Usategui-Martín, A., additional, Usta, R., additional, Valdés, L., additional, Valente, A., additional, Valentina, T., additional, van Arkel, K., additional, Van Colen, C., additional, Van Der Hal, N., additional, van Franeker, J.A., additional, Van Herwerden, L., additional, Van Loosdrecht, M., additional, van Oyen, A., additional, Vandeperre, F., additional, Vanderlinden, J-P., additional, Vani, D., additional, Vasconcelos, L., additional, Vega-Moreno, D., additional, Ventero, A., additional, Vethaak, A.D., additional, Vianello, A., additional, Vicioso, M., additional, Vieira, L.R., additional, Viršek, M.K., additional, Vos, M., additional, Wahl, M., additional, Wallace, N., additional, Walton, A., additional, Waniek, J.J., additional, Watts, A., additional, Webster, L., additional, Wesch, C., additional, Whitfield, E., additional, Wichels, A., additional, Wieczorek, A.M., additional, Wilcox, C., additional, Williams, R.J., additional, Wong-Wah-Chung, P., additional, Wright, S., additional, Wyles, K.J., additional, Young, R., additional, Yurtsever, M., additional, Yurtsever, U., additional, Zada, L., additional, Zamani, N.P., additional, and Zampetti, G., additional

Published
2017
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46. Defining the Baselines and Standards for Microplastics Analyses in European Waters (JPI-O BASEMAN)

Author

Gerdts, G., primary, Thomas, K., additional, Herzke, D., additional, Haeckel, M., additional, Scholz-Böttcher, B., additional, Laforsch, C., additional, Lagarde, F., additional, Mahon, A.M., additional, Pedrotti, M.L., additional, de Lucia, G.A., additional, Sobral, P., additional, Gago, J., additional, Lorenzo, S.M., additional, Noren, F., additional, Hassellöv, M., additional, Kögel, T., additional, Tirelli, V., additional, Caetano, M., additional, Collignon, A., additional, Lips, I., additional, Mallow, O., additional, Seatala, O., additional, Goede, K., additional, and Licandro, P., additional

Published
2017
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48. Proteus: An Architecture for Adapting Web Page on Small-Screen Devices

Author

Caetano, M. F., Fialho, A. L. F., Bordim, J. L., Castanho, C. D., Jacobi, R. P., Nakano, K., Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Li, Keqiu, editor, Jesshope, Chris, editor, Jin, Hai, editor, and Gaudiot, Jean-Luc, editor

Published
2007
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50. Metals concentrations in transitional and coastal waters by ICPMS and voltammetry analysis of spot samples and passive samplers (DGT)

Author

Caetano, M., Correia dos Santos, M.M., Rosa, N., Carvalho, I., Rodríguez, J.G., Belzunce-Segarra, M.J., Menchaca, I., Larreta, J., Sanz, M.R., Millán-Gabet, V., Gonzalez, J.-L., Amouroux, I., Guesdon, S., Menet-Nédélec, F., White, B., Regan, F., Nolan, M., McHugh, B., Bersuder, P., Bolam, T., Robinson, C.D., Fones, G.R., Zhang, H., Schintu, M., Montero, N., Marras, B., Caetano, M., Correia dos Santos, M.M., Rosa, N., Carvalho, I., Rodríguez, J.G., Belzunce-Segarra, M.J., Menchaca, I., Larreta, J., Sanz, M.R., Millán-Gabet, V., Gonzalez, J.-L., Amouroux, I., Guesdon, S., Menet-Nédélec, F., White, B., Regan, F., Nolan, M., McHugh, B., Bersuder, P., Bolam, T., Robinson, C.D., Fones, G.R., Zhang, H., Schintu, M., Montero, N., and Marras, B.

Abstract

This study investigates the relationships among Ni, Cd and Pb's different chemical forms determined by different methodologies in coastal and transitional waters across a broad geographical scale. Concentrations were measured in spot samples and through passive sampling (DGT). High variability of metal concentrations was found among sampling sites and methodologies due to natural water fluctuations rather than to a given metal or method. Total dissolved metal concentrations in spot samples were lower than the EQS-WFD values. The labile fractions of Cd and Pb, measured in spot samples by Anodic Stripping Voltammetry and by DGT-ICPMS, were highly correlated. Similar labilities were found for Cd, while for Pb, the ASV labile fraction was ≈50% lower. These results reflect the pool of mobile and labile species available towards each technique kinetic window, and they seem not to be affected by discrete sampling flaws.

Published
2022

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