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14 results on '"Cabula, Carlo"'

1. Is routine axillary lymph node dissection needed to tailor systemic treatments for breast cancer patients in the era of molecular oncology? A position paper of the Italian National Association of Breast Surgeons (ANISC)

Author

Rocco, Nicola, primary, Ghilli, Matteo, additional, Curcio, Annalisa, additional, Bortul, Marina, additional, Burlizzi, Stefano, additional, Cabula, Carlo, additional, Cabula, Roberta, additional, Ferrari, Alberta, additional, Folli, Secondo, additional, Fortunato, Lucio, additional, Frittelli, Patrizia, additional, Gentilini, Oreste, additional, Grendele, Sara, additional, Grassi, Massimo Maria, additional, Grossi, Simona, additional, Magnoni, Francesca, additional, Murgo, Roberto, additional, Palli, Dante, additional, Rovera, Francesca, additional, Sanguinetti, Alessandro, additional, Taffurelli, Mario, additional, Tazzioli, Giovanni, additional, Terribile, Daniela Andreina, additional, Caruso, Francesco, additional, and Galimberti, Viviana, additional

Published
2024
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3. Nipple sparing mastectomy: Surgical and oncological outcomes from a national multicentric registry with 913 patients (1006 cases) over a six year period

Author

Orzalesi, Lorenzo, Casella, Donato, Santi, Caterina, Cecconi, Lorenzo, Murgo, Roberto, Rinaldi, Stefano, Regolo, Lea, Amanti, Claudio, Roncella, Manuela, Serra, Margherita, Meneghini, Graziano, Bortolini, Massimiliano, Altomare, Vittorio, Cabula, Carlo, Catalano, Francesca, Cirilli, Alfredo, Caruso, Francesco, Lazzaretti, Maria Grazia, Cataliotti, Luigi, and Bernini, Marco

Published
2016
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4. Current trends and outcomes of breast reconstruction following nipple-sparing mastectomy: results from a national multicentric registry with 1006 cases over a 6-year period

Author

Casella, Donato, Calabrese, Claudio, Orzalesi, Lorenzo, Gaggelli, Ilaria, Cecconi, Lorenzo, Santi, Caterina, Murgo, Roberto, Rinaldi, Stefano, Regolo, Lea, Amanti, Claudio, Roncella, Manuela, Serra, Margherita, Meneghini, Graziano, Bortolini, Massimiliano, Altomare, Vittorio, Cabula, Carlo, Catalano, Francesca, Cirilli, Alfredo, Caruso, Francesco, Lazzaretti, Maria Grazia, Meattini, Icro, Livi, Lorenzo, Cataliotti, Luigi, and Bernini, Marco

Published
2017
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7. Current trends and outcomes of breast reconstruction following nipple-sparing mastectomy: results from a national multicentric registry with 1006 cases over a 6-year period

Author

Casella, Donato, primary, Calabrese, Claudio, additional, Orzalesi, Lorenzo, additional, Gaggelli, Ilaria, additional, Cecconi, Lorenzo, additional, Santi, Caterina, additional, Murgo, Roberto, additional, Rinaldi, Stefano, additional, Regolo, Lea, additional, Amanti, Claudio, additional, Roncella, Manuela, additional, Serra, Margherita, additional, Meneghini, Graziano, additional, Bortolini, Massimiliano, additional, Altomare, Vittorio, additional, Cabula, Carlo, additional, Catalano, Francesca, additional, Cirilli, Alfredo, additional, Caruso, Francesco, additional, Lazzaretti, Maria Grazia, additional, Meattini, Icro, additional, Livi, Lorenzo, additional, Cataliotti, Luigi, additional, and Bernini, Marco, additional

Published
2016
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8. Local treatment with electrochemotherapy of superficial angiosarcomas: Efficacy and safety results from a multi‐institutional retrospective study

Author

Guida, Michele, primary, Campana, Luca G., additional, Curatolo, Pietro, additional, Strippoli, Sabino, additional, Bonadies, Antonio, additional, Grilz, Gretha, additional, Cabula, Carlo, additional, Rotunno, Roberta, additional, Bucher, Stefania, additional, Solari, Nicola, additional, Santoriello, Antonio, additional, Valpione, Sara, additional, and Rossi, Carlo R., additional

Published
2016
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9. BP103 ELECTROCHEMOTHERAPY IN THE TREATMENT OF CUTANEOUS METASTASES FROM BREAST CANCER: A MULTICENTER COHORT ANALYSIS

Author

Agresti, Roberto, primary, Cabula, Carlo, additional, Campana, Luca, additional, Grilz, Gretha, additional, Bussone, Riccardo, additional, Galuppo, Sara, additional, Valpione, Sara, additional, De Meo, Leonardo, additional, Bonadies, Antonio, additional, Curatolo, Pietro, additional, De Laurentiis, Michelino, additional, Renne, Maria, additional, Fabrizio, Tommaso, additional, Solari, Nicola, additional, Guida, Michele, additional, Santoriello, Antonio, additional, and D'Aiuto, Massimiliano, additional

Published
2015
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12. Local treatment with electrochemotherapy of superficial angiosarcomas: efficacy and safety results from a multi-institutional retrospective study.

Author

Guida, Michele, Campana, Luca Giovanni, Strippoli, Sabino, Curatolo, Pietro, Bonadies, Antonio, Grilz, Gretha, Cabula, Carlo, Rotunno, Roberta, Bucher, Stefania, Solari, Nicola, Santoriello, Antonio, and Rossi, Carlo Riccardo

Subjects
CANCER chemotherapy, ANGIOSARCOMA, DRUG efficacy, TUMORS, ANTINEOPLASTIC agents
Published
2016
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13. Nipple sparing mastectomy: Surgical and oncological outcomes from a national multicentric registry with 913 patients (1006 cases) over a six year period

Author

Alfredo Cirilli, Francesca Catalano, Donato Casella, C. Cabula, Roberto Murgo, Marco Bernini, Massimiliano Bortolini, Vittorio Altomare, L. Regolo, Claudio Amanti, Lorenzo Cecconi, F. Caruso, Caterina Santi, Maria Grazia Lazzaretti, Lorenzo Orzalesi, Graziano Meneghini, Margherita Serra, Manuela Roncella, Stefano Rinaldi, Luigi Cataliotti, Orzalesi, Lorenzo, Casella, Donato, Santi, Caterina, Cecconi, Lorenzo, Murgo, Roberto, Rinaldi, Stefano, Regolo, Lea, Amanti, Claudio, Roncella, Manuela, Serra, Margherita, Meneghini, Graziano, Bortolini, Massimiliano, Altomare, Vittorio, Cabula, Carlo, Catalano, Francesca, Cirilli, Alfredo, Caruso, Francesco, Lazzaretti, Maria Grazia, Cataliotti, Luigi, and Bernini, Marco

Subjects
Adult, Nipple-Sparing Mastectomy, medicine.medical_specialty, Nipple areola complex necrosi, locoregional breast recurrences, Mastectomy, Subcutaneous, Breast Neoplasms, 030230 surgery, national registry, nipple areola complex necrosis, nipple areola complex recurrences, nipple sparing mastectomy, surgery, Surgical Flaps, Necrosis, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Nipple areola complex recurrence, medicine, Humans, Prospective Studies, Registries, Single institution, Young adult, Prospective cohort study, Aged, Retrospective Studies, business.industry, Retrospective cohort study, General Medicine, Odds ratio, Middle Aged, National registry, Surgery, Treatment Outcome, Italy, Nipples, 030220 oncology & carcinogenesis, Female, National database, Locoregional breast recurrence, Neoplasm Recurrence, Local, business, Nipple sparing mastectomy
Abstract

Background Nipple sparing mastectomy is deemed surgically and oncologically safe based on a long lasting literature data from reviews of single institution series. This study aims at evaluating surgical and oncological outcomes of NSM on a large multi-institutional scale, by means of the Italian National registry. Methods In July 2011 a panel of Italian specialists agreed upon and designed a National database of NSM. Centers with at least 150 cancers per year and following the National follow-up schedule guidelines could participate inserting any NSM case performed, retrospectively and prospectively from that moment on. In March 2015 analysis of data was accomplished. Dataset for this study consists of cases performed in the period between January 1st 2009 and December 31st 2014. Results 913 Women were included in the analysis, for a total of 1006 procedures. Prophylactic mastectomies were 124 (12.3%). MRI utilization increased over time. NSM failure rate, with NAC removal for any reason was 11.5%. NAC necrosis rate was 4.8%. Larger skin-flap necrosis rate was 2.3%. Major surgical complications rate was 4.4%. Oncological outcomes were calculated among primitive EBC cases only: locoregional recurrences rate was 2.9%, NAC recurrence 0.7%. Systemic recurrence rate was 1.0%. Five deaths (0.7%) were registered. Conclusions More than 10% of NSM procedures are prophylactic mastectomies. MRI is gaining more importance over time. Surgical and oncological results show that NSM is effective. This National multicentric analysis enables a comparison of results with no geographical differences and a "safe" state of the art of NSM in Italy.

Published
2016

14. Treatment strategies with electrochemotherapy for limb in-transit melanoma: Real-world outcomes from a European, retrospective, cohort study.

Author

Campana LG, Tauceri F, Bártolo J, Calabrese S, Odili J, Carrara G, Farricha V, Piazzalunga D, Bottyán K, Bisarya K, Mascherini M, Clover JA, Sestini S, Bošnjak M, Kis E, Fantini F, Covarelli P, Brizio M, Sayed L, Cabula C, Careri R, Fabrizio T, Eisendle K, MacKenzie Ross A, Schepler H, Borgognoni L, Sersa G, and Valpione S

Abstract

Background: This study analysed treatment strategies with electrochemotherapy (ECT) in melanoma with limb in-transit metastases (ITM)., Methods: We audited AJCC v.8 stage IIIB-IIID patients treated across 22 centres (2006-2020) within the International Network for Sharing Practices of ECT (InspECT)., Results: 452 patients were included, 58 % pre-treated (93 % had lower limb ITM, 44 % had ≤10 metastases [median size 1.5 cm]. Treatment strategies included first-line ECT (n = 145, 32 %), ECT with concurrent locoregional/systemic treatment (n = 163, 36 %), and salvage ECT (n = 144, 32 %). The objective response rate was 63 % (complete response [CR], 24 %), increasing to 74 % (CR, 39 %) following retreatment (median two ECT, range 1-8). CR rate in treatment-naïve and pre-treated patients was 50 % vs 32 % (p < 0.001). Bleomycin de-escalation was associated with lower CR (p = 0.004). Small tumour number and size, hexagonal electrode, retreatment, and post-ECT skin ulceration predicted response in multivariable analysis. At a median follow-up of 61 months, local and locoregional recurrence occurred in 55 % and 81 % of patients. Median local progression-free, new lesions-free, and regional recurrence-free survival were 32.9, 6.9, and 7.7 months. Grade-3 toxicity was 15 %. Concurrent treatment and CR correlated with improved regional control and survival. Concomitant checkpoint inhibition did not impact toxicity or survival outcomes. The median overall survival was 5.7 years., Conclusions: Among patients with low-burden limb-only ITM, standard-dose bleomycin ECT results in durable local response. Treatment naivety, low tumour volume, hexagonal electrode application, retreatment, and post-ECT ulceration predict response. CR and concurrent treatment correlate with improved regional control and survival outcomes. Combination with checkpoint inhibitors is safe but lacks conclusive support., Competing Interests: Declaration of competing interest LGC, JO, MM, JAC, EK, MB, RC, AM, HS, and GS received travel grants unrelated to this work from Igea Clinical Biophysics S.p.A. (Carpi, Italy). FT, JB, SC, GC, VF, DP, KB, KB, SS, MB, FF, PC, LS, CC, TF, KE, LB, and SV have no conflicts of interest to declare., (Copyright © 2024 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.)

Published
2024
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