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Since the declaration of the COVID-19 pandemic health care, public health, first responders, and other essential workers have been engaged in the most extensive emergency response in more than a century, whilst trust in science has been eroded and public health has been politicized. Against this context, the authors in this collection assess the potential mental health impacts, widening disparities, and needed interventions for future resilience of the public health workforce. What actions can be taken now to ensure more resilient systems post-pandemic? Focusing on the impacts of the pandemic on responder health across health care, public health, emergency management, and more, the chapters, written by experts in the field, provide an overview of the mental health impacts of disasters and emergencies on responders more broadly, and also highlight the inequitable impacts of the response among sectors of the workforce and populations who are socially or physically vulnerable. Closing with recommendations for changes that are needed to address gaps in capacity, COVID-19, Frontline Responders and Mental Health makes a crucial contribution to building the evidence base and disseminating best practices to ensure recommendations become standard practices in the future. Realizing the harsh potential realities such as a shortage of qualified workers and questions around funding and workforce development needed to ensure preparedness for the next public health emergency, this playbook for delivering resilient public health systems post-pandemic provides a timely oversight for future resilience.

An Epidemiological Update on COVID-19 brings recent findings about the pandemic to the forefront. The reference is a compilation of eleven chapters contributed by expert scholars in epidemiology and medicine that cover topics of interest to anyone interested in COVID-19 monitoring and response measures. The topics also indicate some clinical areas of interest to COVID-19 researchers that have received attention due to the pandemic. It covers basic knowledge about respiratory conditions associated with SARS-CoV-2 infection and COVID-19 epidemiology. These topics are complemented with chapters detailing the symptoms and biochemical mechanisms of novel coronavirus infections intended for readers with an advanced level of understanding of life sciences and medicine. Special topics such as the immune response to Sars-CoV-2, and, recombinant drugs for COVID-19, are also covered in this book. Each chapter is organized in a reader-friendly format and includes a list of references.

On March 11, 2020 the World Health Organization declared the COVID-19 pandemic and life as we knew it paused indefinitely. Confusion, doubts and uncertainty became daily companions as the world watched the pandemic consume country after country.At the University of British Columbia, Canada, a class of aspiring epidemiologists partnered with the professionals working at the frontline of COVID-19 healthcare and research, to examine key questions which would capture a snapshot of the historical pandemic.What caused this outbreak? How does a virus spread? What are the best potential treatments; how did we achieve the development of vaccines, and how do they work? What are the strategies to tackle a two-front war against the virus and the spread of dangerous misinformation and pseudoscience? These questions and more are examined throughout this volume.

This book presents a comprehensive account of the COVID-19 pandemic, also known as the novel coronavirus pandemic, as it happened.This volume examines the first responses to the COVID-19 pandemic, the contexts of earlier epidemics and the epidemiological basics of infectious diseases. Further, it discusses patterns in the spread of the disease; the management and containment of infections at the personal, national, and global level; effects on trade and commerce; the social and psychological impact on people; the disruption and postponement of international events; the role of various international organizations like the WHO in the search for solutions; and the race for a vaccine or a cure.Based on new data and latest developments, the second edition of this volume explores the global spread of COVID-19 since 2019 and examines the emergence of the evolving coronavirus variants (Alpha, Beta, Gamma, Delta and Omicron). Further, it extensively discusses what we have since discovered on the disease, along with recent progress on treatments and vaccines.Authored by a medical professional and an economist working on the frontlines, this book gives a nuanced, verified and fact-checked analysis of the COVID-19 pandemic and its global response. A one-stop resource on the COVID-19 outbreak, it is indispensable for every reader and a holistic work for scholars and researchers of medical sociology, public health, political economy, public policy and governance, sociology of health and medicine, and paramedical and medical practitioners. It will also be a great resource for policymakers, government departments and civil society organizations working in the area.

This book is useful for administrators of different levels involved in counteracting COVID-19, surveillance professionals, clinicians, researchers specializing in epidemiology, microbiology, and infectious diseases, and politicians / legislators engaged in public health sector.We use an innovative approach of combining both epidemiological and sociological analyses, as the very problem is mainly an issue of correct governance. A team of authors from Europe, Russia and China summarizes their experience and knowledge useful for containing SARS-CoV-2 and overcoming social and managerial consequences of the pandemic. The editors are sure that sharing our different experience would help to elaborate necessary strategies, protocols, and principles that may be effectively applied in the future to avoid dramatic consequences of not only COVID-19 but also any possible epidemiological hazards for people and medicine.

This volume presents a comprehensive account of the COVID-19 pandemic, also known as the novel coronavirus pandemic, as it happened. Originating in China in late 2019, the COVID-19 outbreak spread across the entire world in a matter of three to four months. This volume examines the first responses to the pandemic, the contexts of earlier epidemics and the epidemiological basics of infectious diseases. Further, it discusses patterns in the spread of the disease; the management and containment of infections at the personal, national and global level; effects on trade and commerce; the social and psychological impact on people; the disruption and postponement of international events; the role of various international organizations like the WHO in the search for solutions; and the race for a vaccine or a cure. Authored by a medical professional and an economist working on the frontlines, this book gives a nuanced, verified and fact-checked analysis of the COVID-19 pandemic and its global response. A one-stop resource on the COVID-19 outbreak, it is indispensable for every reader and a holistic work for scholars and researchers of medical sociology, public health, political economy, public policy and governance, sociology of health and medicine, and paramedical and medical practitioners. It will also be a great resource for policymakers, government departments and civil society organizations working in the area.

For readers of Plague of Corruption, Thomas S. Cowan, MD, and Sally Fallon Morell ask the question: are there really such things as'viruses'? Or are electro smog, toxic living conditions, and 5G actually to blame for COVID-19? The official explanation for today's COVID-19 pandemic is a “dangerous, infectious virus.” This is the rationale for isolating a large portion of the world's population in their homes so as to curb its spread. From face masks to social distancing, from antivirals to vaccines, these measures are predicated on the assumption that tiny viruses can cause serious illness and that such illness is transmissible person-to-person. It was Louis Pasteur who convinced a skeptical medical community that contagious germs cause disease; his “germ theory” now serves as the official explanation for most illness. However, in his private diaries he states unequivocally that in his entire career he was not once able to transfer disease with a pure culture of bacteria (he obviously wasn't able to purify viruses at that time). He admitted that the whole effort to prove contagion was a failure, leading to his famous death bed confession that “the germ is nothing, the terrain is everything.” While the incidence and death statistics for COVID-19 may not be reliable, there is no question that many people have taken sick with a strange new disease—with odd symptoms like gasping for air and “fizzing” feelings—and hundreds of thousands have died. Many suspect that the cause is not viral but a kind of pollution unique to the modern age—electromagnetic pollution. Today we are surrounded by a jangle of overlapping and jarring frequencies—from power lines to the fridge to the cell phone. It started with the telegraph and progressed to worldwide electricity, then radar, then satellites that disrupt the ionosphere, then ubiquitous Wi-Fi. The most recent addition to this disturbing racket is fifth generation wireless—5G. In The Truth About Contagion: Exploring Theories of How Disease Spreads, bestselling authors Thomas S. Cowan, MD, and Sally Fallon Morell explore the true causes of COVID-19. On September 26, 2019, 5G wireless was turned on in Wuhan, China (and officially launched November 1) with a grid of about ten thousand antennas—more antennas than exist in the whole United States, all concentrated in one city. A spike in cases occurred on February 13, the same week that Wuhan turned on its 5G network for monitoring traffic. Illness has subsequently followed 5G installation in all the major cities in America. Since the dawn of the human race, medicine men and physicians have wondered about the cause of disease, especially what we call “contagions,” numerous people ill with similar symptoms, all at the same time. Does humankind suffer these outbreaks at the hands of an angry god or evil spirit? A disturbance in the atmosphere, a miasma? Do we catch the illness from others or from some outside influence? As the restriction of our freedoms continues, more and more people are wondering whether this is true. Could a packet of RNA fragments, which cannot even be defined as a living organism, cause such havoc? Perhaps something else is involved—something that has upset the balance of nature and made us more susceptible to disease? Perhaps there is no “coronavirus” at all; perhaps, as Pasteur said, “the germ is nothing, the terrain is everything.”

COVID-19 has hit the world unprepared, as the deadliest pandemic of the century. Governments and authorities, as leaders and decision makers fighting the virus, enormously tap into the power of artificial intelligence and its predictive models for urgent decision support. This book showcases a collection of important predictive models that used during the pandemic, and discusses and compares their efficacy and limitations. Readers from both healthcare industries and academia can gain unique insights on how predictive models were designed and applied on epidemic data. Taking COVID19 as a case study and showcasing the lessons learnt, this book will enable readers to be better prepared in the event of virus epidemics or pandemics in the future.

How can we keep up with the deluge of information about COVID-19 and tell which parts are most important and trustworthy?We read:'Scientists recommend','Experts warn','A new model predicts'. How do scientific experts come up with their recommendations? What do their predictions really mean for us, for our friends, and our families?How can we make rational decisions? And how can we have sensible conversations about the pandemic when we disagree?These are the questions that this book is trying to address.It is written in the form of dialogues. Alice, a student of epidemiology, explains the science to three of her fellow students who have a lot of questions for her. The students have the same concerns that we all share to varying degrees: What the pandemic is doing to our health, our economy, and our cherished freedoms. In their conversations, they discover how the science relates to these questions.The book focuses on epidemiology, the science of how infections spread and how the spread can be mitigated. The science of how many infections can be prevented by certain kinds of actions. This is what we need to understand if we want to act wisely, as individuals and as a society.The author's goal is to help the reader think about the COVID-19 pandemic like an epidemiologist. About the various preventive measures, what they are trying to accomplish, what the obstacles are. About what is likely to be most effective in the long run at moderate economic and personal cost. About the likely consequences of personal decisions. About how to best protect oneself and others while allowing all of us to lead lives that are as close as possible to normal.While some chapters present slightly more advanced material than others, no scientific background is needed to follow the conversations. The technical concepts are explained in small steps and the occasional calculations in the book require only high-school mathematics.Related Link(s)

In this book volume-2 proposal has been classified into Part IV: Models for SARS-CoV-2 and Part V: Treatment Strategies for SARS-CoV-2. With the emergence of new coronavirus variants, epidemiology, different host tropism permits a thorough analysis of their evolution and acquired adaptability to their host which need different animal models and treatment approaches. No studies are complete without animal models closely related to human physiology to replicate the disease and observe the pathology conditions as in human cases. Such animal models play a vital role in virus pathogenesis and prepare a therapeutic immune response. Here describe bio-engineered transgenic mouse model inserting with specific genes, or CRISPR-Case9 gene-editing tool has been used previously for SARS-CoV and MERS-CoV. The chapter will deal with culture techniques or cell lines for COVID-19—also histopathology of COVID-19, essential proteins that up or down-regulate SARS-CoV-2. The last chapter of this part will describe other diseases having similar signs and symptoms and their differentiation. There is no specific treatment available to date, just symptomatic therapy. However, scientists will elucidate effective antiviral drugs in clinical trials, phytochemicals, photomedicine such as ultraviolet A & B, homemade remedies, blood plasma transfusion, stem cell therapy, and computational approaches in vivo and in vitro trials. This book will appear as a baseline for academicians, scientists, and health professionals as still, research is going to overcome this outbreak of COVID-19, the novelty of best animal models, and find an effective treatment. However, just a single book proposal like this wouldn't have flourished without enthusiasm and determined publishers'and investigators'strength to take time from their busy schedule and subsidize on time. We thank the whole investigators who contributed, directly and indirectly, to bring it to reality.

COVID-19: Epidemiology, Biochemistry, and Diagnostics explains COVID-19 from multidisciplinary angles such as the evolution of SARS-COV, genetic techniques to study the virus, and diagnostic methodologies widely used in the global COVID-19 pandemic.The chapters in this book provide the reader with up-to-date literature about research on SARS-CoV-2 through three parts:I) Evolution and Entry of SARS-CoV-2 into the hostII) Genetic Alteration and Structural Determination of SARS-CoV-2 ProteinsIII) Quantitative Analysis of SARS-CoV-2 for research and medical diagnosisKey Features:- 15 chapters on SAR-CoV-2 in a multidisciplinary context- Provides a comprehensive overview of SARS-CoV-2 evolution and genetics- Provides biochemical information about SARS-CoV-2 proteins and receptor targets (both structural and non-structural proteins)- Includes an overview of several methods of detecting SARS-CoV-2 virus particles (ELISA, PCR, Neutralizing Antibodies- Covers some critical diagnostic modalities for COVID-19 diagnosis- Provides bibliographic references for further readingReaders will understand the significance of phylogenetic analysis of coronaviruses, along with the pathogenesis of COVID-19 and related diseases such as SARS and MERS. Applications of biochemical technologies such as RT-PCR and CRISPR are also demonstrated in the text. This book is a comprehensive introduction to COVID-19 research for medical researchers, microbiologists and virologists. Students in academic programs in life sciences and medicine will also benefit from the information provided in the book.

In December 2019, new cases of severe pneumonia were first detected in Wuhan, China, and the cause was determined to be a novel beta coronavirus related to the severe acute respiratory syndrome (SARS) coronavirus that emerged from a bat reservoir in 2002. Within six months, this new virus—SARS coronavirus 2 (SARS-CoV-2)—has spread worldwide, infecting at least 10 million people with an estimated 500,000 deaths. COVID-19, the disease caused by SARS-CoV-2, was declared a public health emergency of international concern on January 30, 2020 by the World Health Organization (WHO) and a pandemic on March 11, 2020. To date, there is no approved effective treatment or vaccine for COVID-19, and it continues to spread in many countries. Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2: Modernizing Pandemic Response Strategies lays out a framework to define and describe the data needs for a system to track and correlate viral genome sequences with clinical and epidemiological data. Such a system would help ensure the integration of data on viral evolution with detection, diagnostic, and countermeasure efforts. This report also explores data collection mechanisms to ensure a representative global sample set of all relevant extant sequences and considers challenges and opportunities for coordination across existing domestic, global, and regional data sources.

Coronavirus disease 2019 (COVID 19) is a viral infection caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). The disease was first identified in 2019 in Wuhan, China, and has since spread globally into a pandemic. The outbreak was declared a Public Health Emergency of International Concern on January 30, 2020 by the World Health Organization. The disease has spread to almost 200 countries and continues to do so, resulting in huge mortalities and morbidities, as well as economic burden on the affected countries. The pandemic has resulted in global shutdown and has impacted many lives. This book analyzes the epidemiology of COVID 19, the characteristics of the virus, its mode of spread, pathogenesis, pathology, clinical presentation, diagnosis, prevention, and prognosis. The impact of the disease on the health care system, its psycho-social implications, and its impact on the economy is also discussed in detail. This will serve as a reference manual for physicians, students, epidemiologists and researchers in the field. Knowledge about the infection is fast-evolving, hence readers are advised to review the latest guidelines, especially concerning the management of cases of COVID 19.

Surveying the Covid-19 Pandemic and Its Implications: Urban Health, Data Technology and Political Economy explores social, economic, and policy impacts of COVID-19 that will persist for some time. This timely book surveys the COVID-19 from a holistic, high level perspective, examining such topics as Urban health policy responses impact on cities economies, Urban economic impacts of supply chain disruption, The need for coherent short term urban policies that aligns with long term goals, The rise to citizen science initiatives, The role of open data, The need for protocols to support research collaborations, Building larger infectious disease modelling datasets, NS Advanced computing tools for health policy. - Includes the most hot topical issues surrounding COVID-19 - Provides an urban viewpoint on COVID-19 and its effects on urban health - Presents a multidisciplinary perspective

A history of COVID-19 and the sociopolitical crises that led to the 2020 global pandemicThe COVID-19 pandemic shocked the world. It shouldn't have. Since this century's turn, epidemiologists have warned of new infectious diseases. Indeed, H1N1, H7N9, SARS, MERS, Ebola Makona, Zika, and a variety of lesser viruses have emerged almost annually. But what of the epidemiologists themselves? Some bravely descended into the caves where bat species hosted coronaviruses, including the strains that evolved into the COVID-19 virus. Yet, despite their own warnings, many of the researchers appear unable to understand the true nature of the disease—as if they are dead to what they've seen.Dead Epidemiologists is an eclectic collection of commentaries, articles, and interviews revealing the hidden-in-plain-sight truth behind the pandemic: Global capital drove the deforestation and development that exposed us to new pathogens. Rob Wallace and his colleagues—ecologists, geographers, activists, and, yes, epidemiologists—unpack the material and conceptual origins of COVID-19. From deepest Yunnan to the boardrooms of New York City, this book offers a compelling diagnosis of the roots of COVID-19, and a stark prognosis of what—without further intervention—may come.