1. Gender differences in predictors of intensive care units admission among COVID-19 patients: The results of the SARS-RAS study of the Italian Society of Hypertension
- Author
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Iaccarino G, Grassi G, Borghi C, Carugo S, Fallo F, Ferri C, Giannattasio C, Grassi D, Letizia C, Mancusi C, Minuz P, Perlini S, Pucci G, Rizzoni D, Salvetti M, Sarzani R, Sechi L, Veglio F, Volpe M, Muiesan ML, SARS-RAS Investigators, Iaccarino G, Grassi G, Borghi C, Carugo S, Fallo F, Ferri C, Giannattasio C, Grassi D, Letizia C, Mancusi C, Minuz P, Perlini S, Pucci G, Rizzoni D, Salvetti M, Sarzani R, Sechi L, Veglio F, Volpe M, Muiesan ML, SARS-RAS Investigators, Iaccarino, G, Grassi, G, Borghi, C, Carugo, S, Fallo, F, Ferri, C, Giannattasio, C, Grassi, D, Letizia, C, Mancusi, C, Minuz, P, Perlini, S, Pucci, G, Rizzoni, D, Salvetti, M, Sarzani, R, Sechi, L, Veglio, F, Volpe, M, Muiesan, M, Iaccarino, G., Borghi, C., Carugo, S., Fallo, F., Ferri, C., Giannattasio, C., Grassi, D., Letizia, C., Mancusi, C., Minuz, P., Perlini, S., Pucci, G., Rizzoni, D., Salvetti, M., Sarzani, R., Sechi, L., Veglio, F., Volpe, M., Muiesan, M. L., and SARS-RAS Investigator
- Subjects
COVID-19, gender, obesity ,Male ,Pulmonology ,Cross-sectional study ,Disease ,Cardiovascular Medicine ,covid , gender ,Vascular Medicine ,Severity of Illness Index ,Covid ,law.invention ,Adolescent ,Adult ,Aged ,Aged, 80 and over ,Betacoronavirus ,Coronavirus Infections ,Cross-Sectional Studies ,Female ,Heart Failure ,Humans ,Hypertension ,Italy ,Middle Aged ,Obesity ,Pandemics ,Pneumonia, Viral ,Renal Insufficiency, Chronic ,Risk Factors ,Sex Factors ,Young Adult ,Intensive Care Units ,Patient Admission ,0302 clinical medicine ,Medical Conditions ,Endocrinology ,Health care ,80 and over ,Medicine ,Chronic ,Nephrology ,Cardiovascular Diseases ,Human ,medicine.medical_specialty ,Endocrine Disorders ,Science ,Intensive Care Unit ,COVID-19 ,SARS-CoV-2 ,03 medical and health sciences ,Intensive care ,Severity of illness ,Renal Diseases ,Diabetes Mellitus ,Cross-Sectional Studie ,Betacoronaviru ,Biology and Life Sciences ,Correction ,Covid 19 ,Pneumonia ,Clinical trial ,Health Care ,Health Care Facilities ,Observational study ,SARS_CoV-2 ,Viral Diseases ,Physiology ,Sex Factor ,030204 cardiovascular system & hematology ,law ,Chronic Kidney Disease ,Medicine and Health Sciences ,Coronary Heart Disease ,030212 general & internal medicine ,Viral ,Renal Insufficiency ,intensive care ,Multidisciplinary ,SARS_CoV-2, Gender, intensive care, prediction ,Intensive care unit ,Hospitals ,Infectious Diseases ,Physiological Parameters ,Research Article ,Chronic Obstructive Pulmonary Disease ,Cardiology ,Pandemic ,business.industry ,Coronavirus Infection ,Risk Factor ,Body Weight ,Gender ,prediction ,Hyperyension ,Metabolic Disorders ,Emergency medicine ,business - Abstract
BackgroundThe global rate of intensive care unit (ICU) admission during the COVID-19 pandemic varies within countries and is among the main challenges for health care systems worldwide. Conflicting results have been reported about the response to coronavirus infection and COVID-19 outcomes in men and women. Understanding predictors of intensive care unit admission might be of help for future planning and management of the disease.Methods and findingsWe designed a cross-sectional observational multicenter nationwide survey in Italy to understand gender-related clinical predictors of ICU admission in patients with COVID-19. We analyzed information from 2378 charts of Italian patients certified for COVID-19 admitted in 26 hospitals. Three hundred ninety-five patients (16.6%) required ICU admission due to COVID19 infection, more frequently men (74%), with a higher prevalence of comorbidities (1,78±0,06 vs 1,54±0,03 pConclusionsOur study demonstrates that gender is the primary determinant of the disease's severity among COVID-19. Obesity is the condition more often observed among those admitted to ICU within both genders.Trial registrationClinicaltrials.gov: NCT04331574.
- Published
- 2020