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This paper intends to enhance the corrosion resistance of coolant pipes in thermal fatigue conditions and lateral hydrostatic pressure in critical engineering environments. This research applies to circular coolant pipes under hydrostatic pressure of the LBE (lead-bismuth eutectic) boundary in nuclear power plants. The resistance against corrosion caused by liquid LBE is mainly formed by Fe12Cr2Si solid solutions coatings on the pipe. The silicon concentration in Fe12Cr2Si can interact with LBE as an effective oxidized compound such as SiO2 and Fe2SiO4 when the silicon concentration is above 1.25 wt%. The oxide film formed on the coating can resist the LBE corroding in the Fe12Cr2Si structure. The primary material for constructing a coolant pipe is T91 ferritic-martensitic alloys, and the surface anti-corrosion coating is Fe12Cr2Si solid solution. With a high-strength structure, FGC (functionally graded composite material) ensures that the pipe resists the corrosion from Liquid LBE. This study evaluates the thermal fatigue failure of coolant pipes and the silicon concentration when the pipe model is under thermal shock testing by a CO2 laser. The research result indicates that the FGM (functionally graded material) structure performs better in effectively raising the margin of safety and reserving the silicon concentration on the inner surface higher than 1.25 wt% as compared to the FGC structure. [ABSTRACT FROM AUTHOR]

Background: Macular amyloidosis (MA) could be of cosmetic concern with a significant psychological impact for patients, and its treatment is challenging. Aim of the work: To compare the efficacy and safety of combined fractional CO2 laser with dimethyl sulfoxide (DMSO) 50% versus fractional CO2 laser alone in the treatment of macular amyloidosis. Patients and methods: Twenty patients with macular amyloidosis were treated with monthly session of fractional CO2 laser only in one side of the lesion (area A), and fractional laser followed by application of DMSO 50% solution in the other side of the lesion (area B). All patients were evaluated clinically, by dermoscope and histopathology before and 3 months after the end of 4 treatment sessions. Results: Both treatments showed significant decrease of pigmentation after treatment (p < 0.001). There was non-significant decrease in rippling on both sides (p = 0.06). The median itching score dropped significantly after treatment from 9 to 3.5 in area A (laser only) and to 2 in area B (laser and DMSO), with non-significant difference between both areas (P = 0.244). Dermoscopic features after treatment showed fading and decreasing in multiple features in both areas A and B, with non-significant difference between the 2 areas. Histopathologically, there was significant reduction in the amyloid deposition after treatment in both areas A and B without significant difference between both areas. Conclusion: both fractional CO2 laser combined with topical DMSO 50% and fractional CO2 laser alone are safe and effective treatment options for MA with significant clinical improvement. [ABSTRACT FROM AUTHOR]

Laser-induced graphene (LIG) has become a highly promising material for flexible functional devices due to its robust mechanical stability, excellent electrical properties, and ease of fabrication. Most research has been focused on LIG production on rigid or flexible substrates, with an obvious gap in laser induction of graphene on elastic, stretchable substrates, which limits the scope of application of LIG in flexible electronics. We demonstrate laser induction of graphene on a novel, cross-linked poly(dimethylsiloxane) (PDMS)/Triton X-100 composite substrates. The effect of varying Triton content (1–30 wt.%) on the structural, thermal, surface, nanomechanical, and electrical properties of LIG was systematically studied. Physicochemical characterization confirmed the successful induction of LIG on the surface of PDMS/Triton composites. A higher content of Triton in the PDMS matrix improves the quality of LIG, increases stiffness and hydrophobicity, and somewhat decreases sheet resistance. Similar thermal properties and super-hydrophobicity were observed for LIG/PDMS/Triton materials as compared to their counterparts without LIG. Direct laser irradiation of graphene on the surface of PDMS/Triton composites results in the formation of extremely promising materials, which have great potential for use in flexible electronic devices. [ABSTRACT FROM AUTHOR]

Striae distensae (SD) are a prevalent dermatological concern of women and approximately 90% of pregnant women experience these stretch marks. Fractional microneedle radiofrequency (FMR) and fractional CO2 laser (FCL) have gained substantial attention in the treatment of SD. In clinical studies, a clear superiority between FMR and FCL treatments is not found due to limited studies and sample sizes. In this systematic review and meta-analysis, a search of English-language articles was performed on PubMed, employing various combinations of keywords "fractional CO2 laser," "microneedle radiofrequency," and "striae". Studies that compared the treatments of FMR and FCL for SD and provided data regarding professional evaluation of improvement, patient self-assessment, and/or the presence of post-inflammatory hyperpigmentation (PIH) were included. We analyzed the incorporated studies utilizing both random and fixed-effects models to estimate pooled odds ratios (OR) and 95% confidence intervals (CI). Professional assessments of improvement showed no statistically significant difference between the FMR and FCL groups (OR: 1.27; 95% CI: 0.49–3.31). Similarly, patient self-assessments of improvement did not exhibit a significant difference (OR: 0.72; 95% CI: 0.13–3.90). However, the development of PIH was significantly less frequent in the FMR group when compared to the FCL group (OR: 0.24; 95% CI: 0.08–0.70). Both FMR and FCL demonstrate comparable performance in terms of improving lesions, as assessed by both healthcare professionals and patients. However, FCL is associated with a higher risk of developing PIH. This finding can guide clinicians especially who prefer a single treatment. [ABSTRACT FROM AUTHOR]

Here, we describe for the first time the fabrication of laser‐induced graphene (LIG) electrodes on a hybrid substrate composed of sandpaper and polyester. As a proof of concept, the proposed device was used as a voltammetric sensor for tadalafil (TAD) quantification in authentic tablet samples. The electrochemical TAD sensing based on differential pulse voltammetry (DPV) revealed a linear behavior in the concentration range from 25 to 250 μmol L−1(R2=0.99), a limit of detection of ~9.6 μmol L−1, sensitivity of ~0.0048 μA(μmol L−1)−1 and acceptable reproducibility values (RSD≤5.8 %). The DPV responses involving the standard addition method in pharmaceutical samples presented recovery results of TAD ranging from 93 to 108 %. Also, the proposed analytical method offered a suitable green analytical chemistry profile. We successfully demonstrated the fabrication of graphene‐like sites and nanoparticles composed of alumina upon a hybrid substrate. [ABSTRACT FROM AUTHOR]

The triboelectric nanogenerator (TENG) has demonstrated exceptional efficiency in harvesting diverse forms of mechanical energy and converting it into electrical energy. This technology is particularly valuable for powering low-energy electronic devices and self-powered sensors. Most traditional TENGs use single-sided patterned friction pairs, which restrict their effective contact area and overall performance. Here, we propose a novel TENG that incorporates microwave patterned aluminum (MC-Al) foil and microcone structured polydimethylsiloxane (MC-PDMS). This innovative design utilizes two PMMA molds featuring identical micro-hole arrays ablated by a CO2 laser, making it both cost-effective and easy to fabricate. A novel room imprinting technique has been employed to create the micromorphology of aluminum (Al) foil using the PMMA mold with shallower micro-hole arrays. Compared to TENGs with flat friction layers and single-side-patterned friction layers, the double-side-patterned MW-MC-TENG demonstrates superior output performance due to increased cone deformation and contact area. The open-circuit voltage of the MW-MC-TENG can reach 141 V, while the short-circuit current can attain 71.5 μA, corresponding to a current density of 2.86 µA/cm2. The power density reaches 1.4 mW/cm2 when the resistance is 15 MΩ, and it can charge a 0.1 μF capacitor to 2.01 V in 2.28 s. In addition, the MW-MC-TENG can function as an insole device to harvest walking energy, power 11 LED bulbs, monitor step speed, and power a timer device. Therefore, the MW-MC-TENG has significant application potential in micro-wearable devices. [ABSTRACT FROM AUTHOR]

Yttrium‐stabilized zirconia (YSZ) plays a crucial role in thermal barrier coatings widely used to protect metallic components in gas turbine engines against high‐temperature combustion product gases and harsh environments. The thermal conductivity of these coatings is a critical parameter influencing the gas turbine design, performance, and service life. In this study, a laser temperature gradient method is utilized to measure the thermal conductivity of porous YSZ coatings. The method employs specialized laser energy delivery to create a one‐dimensional temperature gradient through the sample thickness, closely simulating the operational condition. This approach provides an effective, direct means to determine the thermal conductivity of high‐temperature heat‐resistant porous ceramic materials. [ABSTRACT FROM AUTHOR]

CO2 Laser and Coblation are widely used in Head and neck Surgeries. This study compares the tissue changes produced by these two techniques. 50 Patients who underwent complete excision of benign and malignant pathologies in the Oral Cavity, Oropharynx, and Larynx with Coblation and CO2 Laser were included in the study. The primary excised specimen and another separate specimen from the base of the excised lesion were evaluated histologically based on criteria by Vescovi et al. (1). On histopathological examination, thermal effects (epithelial, connective tissue and vascular) produced by both techniques were comparable. However vascular changes were seen more in tissues CO2 Laser (P = 0.727). Incision margins were more regular in the CO2 Laser group (73%) than in Coblation (55%) but not statistically significant (P = 1.80). Depth of thermal damage (P = 0.171) and connective tissue changes(P = 0.279) was more with Coblation. Both Coblation and CO2 Laser can be used effectively in Head and Neck cases. CO2 Laser, when available, is a better option because of its precise excision, and less collateral tissue damage. [ABSTRACT FROM AUTHOR]

Objective To present a new treatment for ingrown toenail with CO2 laser that is easy to perform, without damage the nail, nail matrix and nail bed. Methods A total of 21 ingrown toenail (IGT) lesions of the big toe in 16 patients who were diagnosed as ingrown toenail were treated with CO2 laser, while tissues along nail groove around the lesion was ablated, ingrown nail plate was exposed and separated. Results A total of 16 patients, with a mean age was (23.38 ± 13.61) years. All the 21 lesions were regressed except 2 with relapse (the cure rate was 90.48%). The time of return to walking, and return to daily activity were (2.25 ±0.66) days and (5.13 ± 0.86) days, respectively. During the 6-35 months follow-up, the cosmetic effect was remarkable with normal appearance and function. There were no complications. Conclusion Ingrown toenail can be surgically treated without matriceetomy and preserved the nail. All necrotic tissue and certain volume of soft tissue surrounding the lesion should be ablated to decompress the nail and reduce inflammation. [ABSTRACT FROM AUTHOR]

Ependymomas are primary CNS tumors representing 3%-6% of all CNS tumors, and 34.5% of ependymomasoccur in the spine. Spinal ependymomas occur most frequently in the cervical spine. Rarely, tumor-associatedsyringomyelia and hematomyelia may complicate cervical spinal ependymomas. Here, the authors present a case ofa 37 year-old gentleman with cervical intramedullary WHO Grade II ependymoma with hematomyelia extendingcephalad to the brainstem. The authors also detail their operative procedure using the OmniGuide CO2 laser andreview current literature on the management of cervical intramedullary ependymoma with tumor-associatedsyringomyelia and/or hematomyelia.

Introduction: High‐flow nasal oxygen (HFNO), or transnasal humidified rapid‐insufflation ventilatory exchange (THRIVE), is a technique providing apneic oxygenation and a degree of ventilation during microlaryngeal surgery. Its use with laser has been questioned due to concern for airway fire. For fire to occur, a triad of ignition source, oxidizer, and fuel source must be present. By using HFNO and eliminating an endotracheal tube (fuel source), it is hypothesized that airway fire risk is minimal. We tested this theory with human cadavers using HFNO with increasing levels of FiO2 while performing microlaryngeal laser surgery. Methods: HFNO was placed on two cadavers, and oxygen was administered at incrementally increasing fraction of inspired oxygen (FiO2) concentrations (30%–100%). Laryngeal microsurgery was conducted with CO2 and KTP lasers applied for 30 s. Oxygen readings were taken at several anatomic locations along the body assessing oxygen concentrations in correlation with increasing FiO2 administration. Results: The use of CO2 and KTP laser on cadaveric vocal folds produced char but no spark or airway fire at any of the tested oxygen concentrations. Apart from the mouth, there was minimal increase in oxygen levels at the surrounding anatomic sites despite elevating FiO2 levels. Conclusion: HFNO may be safe to use during microlaryngeal laser surgery. By eliminating the endotracheal tube as a fuel source, risk of airway fire may be negligible. Our study safely applied CO2 and KTP lasers for an uninterrupted 30 s with HFNO at 70 L/min and 100% FiO2 producing no spark or fire. Level of Evidence: NA Laryngoscope, 135:223–226, 2025 [ABSTRACT FROM AUTHOR]

Introduction: Post-burn hypertrophic scars are an important cause of physical discomfort, limitation of movements, psychological disorders, low self-esteem and reduced quality of life. Treatment for this condition is complex and involves several options. Microneedling, also known as minimally invasive percutaneous collagen induction, is an affordable minimally invasive option that can be combined with other treatments, including ablative ones. Objective: The goal of this study was to present our microneedling approach for the treatment of hypertrophic scars after burns. Method: A prospective study of 15 patients with post-burn hypertrophic scars was conducted between October 2016 and June 2022. All patients were treated with microneedling and drug delivery of triamcinolone. Scars were evaluated using Vancouver Scar Scale (VSS), Burn Scar Assessment Scale (BSAS) and angle measurement for amplitude of movement evaluation of joints. Results: A significant improvement in the VSS score was obtained after microneedling (8.8 ± 0.44 to 4.1 ± 0.98; p = 0.012), especially in the acute group (less than 1 year after burns): 9.3 ± 0.49 to 3.5 ± 1.36; p = 0.041. There was a significant and progressive improvement of the scars throughout the treatment sessions in all criteria evaluated and in the ranges of joint movement (p = 0.012). Conclusion: Our microneedling protocol promoted a significant improvement of post-burn scars, especially in acute hypertrophic scars, and in the amplitude of joint motion. Sequential treatments provided progressive improvement. Level of Evidence IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266. [ABSTRACT FROM AUTHOR]

Traditional waste incineration generates a large amount of exhaust gas, resulting in adverse environmental impacts. Therefore, we developed an organic and intelligent photochemical processing system that utilizes high-energy lasers for incineration, thereby reducing the production of exhaust gas. A large-scale laser machine was set up, incorporating low-cost 2D Light Detection and Ranging (LiDAR) technology for system sensing, which performs angle range and threshold filtering, as well as multispectral laser allocation, integrated with the laser ablation machine system. After testing, the error was <5 mm (<8%), achieving precise object scanning and ranging and solving the problem of manual laser positioning. Experimental results showed that CO2 lasers can effectively process organic materials and medical waste of different sizes. This innovative research will have profound implications for the future development of environmental protection and incineration technologies. In the future, it has widespread application prospects in areas such as pet waste disposal and medical waste treatment. [ABSTRACT FROM AUTHOR]

This study fixates on determining the optimum laser input parameters that simultaneously meet the desired kerf width and depth during CO2 laser cutting of various polymethylmethacrylate (PMMA) sheets. It has three contributions. The first is to model the cutting process of PMMA by polynomial curve fitting as a function of laser power, laser speed, and standoff distance. R-squared (R2), adjusted R2 and root-mean-square error (RMSE) criteria were taken into account to measure the performance of the proposed model. The effect of laser parameters on the process is investigated by analysis of variance (ANOVA) and sensitivity analysis. The second is to optimize the derived nonlinear regression models using genetic algorithm (GA), particle swarm optimization (PSO), whale optimization algorithm (WOA) and ant lion optimization (ALO) metaheuristic methods and compare the performances of the algorithms. The third is to compare the adequacy of the optimization process with the artificial neural network (ANN). The investigations exhibited that the best-fitting polynomials are obtained with the R2 and adjusted R2 values of over 99% and 97%, respectively. ANOVA and sensitivity test revealed that the sensitivity of the laser power, which is the most effective parameter, was 150 at low powers and decreased to 0 as the power value increased. When the nozzle distance is 4.1, the proposed metaheuristics gave effective and sufficiently accurate results. PSO stood out in terms of both best cost value (3.49 × 10–8) and relative error value (0.19%). The relative error of the ANN was found as 3% in terms of kerf depth. [ABSTRACT FROM AUTHOR]

The moisture content of wood influences its machinability and the resulting quality of the machined surface. This study aims to explore the impact of varied moisture content on the final quality of beech wood cut by a CO2 laser (Fagus sylvatica L.). Laser cutting was performed on beech lumbers conditioned at moisture levels of 0%, 8%, 12%, and 18%. The laser-cut specimens were evaluated for surface roughness and waviness by using a stylus surface profilometer at three measuring locations: top, middle, and bottom. The total color difference ΔE was also assessed using a spectrophotometer at the same three locations. The most intriguing findings revealed that surface specimens with higher moisture content are lighter than those with lower moisture content. Specifically, the top areas of specimens with different moisture content exhibited lighter shades than those in the middle and bottom areas. Notably, the surface profile of the specimens remained unaffected by variations in moisture content levels. [ABSTRACT FROM AUTHOR]

Objective: Analyze the duration of symptom‐free intervals following laser wedge excision (LWE) for recurrent idiopathic subglottic stenosis (iSGS). Secondary aim includes evaluating the influence of patient‐related or disease factors. Study Design: Retrospective review. Setting: Tertiary center. Methods: Review of iSGS patients who underwent LWE between 2002 and 2021. LWE patients without prior airway surgery were labeled LWE primary (LWEP) and those with prior history of dilation were labeled LWE secondary (LWES). A conditional frailty repeated events model was used to analyze the median time to recurrence (MTR) for each nth recurrence. Secondary analysis included stratification by use of medical therapy and initial preoperative characteristics of scar (Myer‐Cotton grade, distance between the glottis and superior‐most aspect of scar, DGS; length of scar, DL). Results: Two hundred and ten iSGS patients underwent LWE (131 LWEP, 79 LWES). The proportion of patients experiencing at least 1, 3, 6, and 12 recurrences, respectively, was 68.0% (n = 143), 40.7% (n = 85), 20.0% (n = 42), and 5.2% (n = 11). There was exponential time‐shortening from the 1st to 12th recurrence (P <.0001). While MTR was 4.1 years after the first LWE, this fell to 2.8, 1.7, 1.0, and 0.7 years for the 2nd, 3rd, 6th, and 12th recurrences. Furthermore, LWEP patients experienced longer MTR than LWES counterparts within the first 6 recurrences (P <.01). There was no significant relationship between intersurgical interval and medication adherence, DL, DGS, or grade for recurrences beyond the first (P =.207, P =.20, P =.43, P =.16). Conclusion: Symptom‐free intervals in iSGS shorten with each subsequent recurrence and LWE. The difference in MTR between LWEP and LWES groups was significant within the first 6 recurrences with LWEP having longer MTR. Level of Evidence: 3. [ABSTRACT FROM AUTHOR]

Localized scleroderma (LS), commonly known as morphea, presents a significant clinical challenge due to its chronic, inflammatory nature affecting the skin and potentially underlying tissues. This systematic review explores the innovative approach of combining laser therapy and injectable fillers, specifically hyaluronic acid, for the treatment of LS. We conducted a comprehensive literature review following PRISMA guidelines, examining articles from MEDLINE/PubMed to assess the combined efficacy of these treatments in improving both esthetic and functional outcomes for LS patients. The search yielded 64 articles, with six selected for in-depth analysis for a total of nine patients, covering a range of patient demographics and treatment types. Our review highlights cases where fractional CO2 laser therapy promoted long-term tissue remodeling and instances where hyaluronic acid fillers effectively addressed skin atrophy and volume loss, enhancing both immediate and long-lasting esthetic improvements. The synergy between these treatments suggests a promising dual approach, aiming to maximize esthetic outcomes and to improve the quality of life for LS patients. This review underscores the necessity of further research to establish a comprehensive, evidence-based clinical pathway integrating both treatments for managing LS, thereby enhancing patient satisfaction and addressing the multifaceted nature of this challenging dermatological condition. [ABSTRACT FROM AUTHOR]

Objective: Endoscopic management of subglottic stenosis (SGS) includes a wide range of techniques. This 17‐year review compares treatment outcomes between carbon dioxide (CO2) laser and cold steel. Study Design: Retrospective chart review. Setting: Single tertiary care center. Methods: A chart review was performed for all patients undergoing endoscopic treatment of SGS at Cleveland Clinic between July 12, 2000 and September 1, 2017. Data collected included demographics, stenosis etiology, stenosis severity, comorbidities, treatment modality, and airway procedure history. The primary endpoint was repeated treatment‐free survival (RTFS) within 2 years using a Kaplan‐Meier analysis and Cox proportional hazard model. Results: A total of 139 patients (median [interquartile range] aged 48.7 [37.8, 57.0] years; 83.4% female) were included in the analysis, with etiologies including idiopathic (56.8%), granulomatosis with polyangiitis (25.2%), and intubation (16.5%). All patients underwent either cold steel (107 patients) or CO2 laser (32 patients) lysis of stenosis with concurrent dilation. RTFS within 2 years was 50.2% for CO2 laser and 31.9% for cold steel (hazard ratio [HR] and 95% confidence interval [CI]: 1.69, 0.96‐2.97, P =.07). In patients with no prior airway procedures, there was no difference in RTFS between laser and cold knife (P =.41). However, in patients with prior airway procedures, RTFS was significantly greater in the laser group, even after adjusting for age, smoking history, and stenosis etiology (50.0% vs 16.8%, adjusted HR and CI: 2.82, 1.14‐6.98, P =.025). Conclusion: Endoscopic lysis of SGS with CO2 laser should be considered in revision cases. [ABSTRACT FROM AUTHOR]

Objectives: In-vitro studies were performed on dentin of extracted human molars to investigate the effectiveness of 9.3 μm CO2 laser irradiation to occlude dentinal tubules. The observed occlusion of dentinal tubules with the irradiation was compared with application of three reagents: 2% Sodium Fluoride gel, an aqueous solution of hydroxyapatite nanoparticles and an equal mix of the two. We show that 9.3 μm CO2 laser irradiation occludes dentinal tubules, and the use of laser irradiation produces better occlusion of the opened tubules compared to the use of topical reagents. Methods: Nine extracted and cleaned human molars were cut to obtain dentin disks of thickness of 3–5 mm. Each disc was divided into four quarters, and each quarter served as two samples corresponding to irradiated and non-irradiated group counterparts. Five disks were used to study the effect of various laser irradiation energies on the dentinal tubules to find a good pulse fluence for occlusion of the dentinal tubules, and four disks were used for studying the effects of reagents and irradiation at the pulse fluences found in the first part of the study. The samples were irradiated with a beam diameter of 1 mm (1/e2) at 15 Hz pulse repetition rate, scanned automatically using a set of scanning mirrors. Samples were imaged using Scanning Electron Microscope (SEM) which were processed to determine tubule diameter. Safety of the irradiation treatment was investigated on 6 samples by measuring pulpal temperature rise. The effect of three topical reagents corresponding to 2% Sodium Fluoride gel (F), Hydroxyapatite nanoparticles (HA) and an equal mix of F and HA (HAF) on dentinal tubule occlusion was evaluated and compared with the laser irradiation. Results: In all examined cases, laser irradiation at a fluence of 0.81 J/cm2 resulted in a temperature increase less than 3 °C which is safe, and no surface cracking was observed. There is a threshold pulse fluence of 0.27 J/cm2 above which, laser produced surface melting. At a pulse fluence of 0.81 J/cm2 a layer of recast of melted dentin was formed. Under this layer, peritubular dentin melting and occluding of the dentinal tubules was observed. Application of either F or HA or HAF did not produce visible occlusion effect on open tubules after washing and microbrushing with excess distilled water. Conclusions: 9.3 μm CO2 laser irradiation on extracted human molar dentin at pulse fluence of 0.81 J./cm2 resulted in tubule area reduction by 97% without rising pulpal temperatures to unsafe levels. [ABSTRACT FROM AUTHOR]

In this work, we focus on the prediction of the influence of CO2 laser parameters on the kerf properties of cut spruce wood. Laser kerf cutting is mainly characterized by the width of kerf and the width of the heat-affected zone, which depend on the laser power, cutting speed, and structure of the cut wood, represented by the number of cut annual rings. According to the measurement results and ANN prediction results, for lower values of the laser power (P) and cutting speed (v), the effect of annual rings (ARs) is non-negligible. The results of the sensitivity analysis show that the effect of v increases at higher energy density (E) values. With P in the range between 100 and 500 W, v values between 3 and 50 mm·s−1, and AR numbers between 3 and 11, the combination of P = 200 W and v = 50 mm·s−1, regardless of the AR value, leads to the best cut quality for spruce wood. In this paper, the main goal is to show how changes in the input parameters affect the characteristics of the cutting kerf and heat-affected zones for all possible input parameter values. [ABSTRACT FROM AUTHOR]

Microfluidic devices (MFD) have several applications in the chemical and biomedical analysis field such as mixing two different drugs prescribed to inpatients. Micromixer can be fabricated using laser beam to ablate microchannel on the surface of polymeric substrate. In this work, CO2 laser was used to manufacture MFD on polymethyl methacrylate substrate with straight and zigzag profiles by investigating the effect of processing parameters (scanning speed, laser power and depth of focus) on the ablated microchannel width, depth, aspect ratio (AR) and wettability. The focus is to produce channel with depths from around 50 µm to 1600 µm using one system, hence producing large microchannels which were not studied in most of the report work. Then a CFD model was developed to characterize the effect of channel geometry and liquid diffusivity and speed on the fluids mixing efficiency. The results showed that the crater width, depth, AR, surface hydrophilicity and surface temperature increased with increasing line energy, and the effect of the process dynamics at constant fluences was also investigated. Various channel profiles such as V-shaped and U-shaped cross sections were produced by shifting the focal position of the beam. This is important in the design phase of the channels, since our single pass method of machining offers a full range of AR from around 0.3 up to 2.25, and a channel depth of 47–1600 µm. The results also showed that the mixing efficiency significantly relies on the channel geometry and fluid flow characteristics, with a maximum mixing efficiency of 99.9% was recorded using a squared shaped MFD. [ABSTRACT FROM AUTHOR]

Background There are various surgical treatments on ingrown toenails. However, the treatment without matricectomy, damaging the nail and not operating on the nail bed could be better.Objective To present a new treatment for ingrown toenail that completely preserve the nail and nail matrix.Methods 52 surgical procedures were performed on 47patients with ingrown toenail who applied to Dermatology Department from May 14th, 2021 to March 12th, 2023 were enrolled. A certain volume of soft tissue surrounding the lesion was ablated under local anesthesia.Results 52 surgical procedures were performed on 47patients. All lesions’ results were excellent except 3 with relapse (the cure rate is 94.23%). These cases healed after retreatment. During the minimum of 1 year follow-up, the cosmetic effect was remarkable with normal appearance and function. The mean operative time was 9.83 ± 2.24 min. There were no complications was observed. The mean time for patients returning to walk was1.36 ± 0.49 days.Conclusion This study demonstrates that ingrown toenail can be surgically treated without matricectomy and preserved the nail. All necrotic tissue and certain volume of soft tissue surrounding the lesion should be ablated to decompress the nail and reduce inflammation.

A 57-year-old male with a three-year history of folliculotropic mycosis fungoides (FMF), previously treated systemically, received CO2 laser-assisted photodynamic therapy (PDT) following the recurrence of FMF on the face. The procedure involved a CO2 laser (SmartXide DOT Deka) and the photosensitizing agent methyl aminolevulinate (MAL) (METVIX 160 mg/g Cream, Galderma Medical), in conjunction with a red light-emitting diode lamp (Aktilite CL128, Galderma, wavelength 630 nm). The primary endpoint was the clinical remission of the lesions; the secondary one the evaluation of treatment tolerance, measured using the 11-point (0–10) Numeric Rating Scale (NRS) for burning/pain, heat, and swelling. After a single treatment session and four weeks of follow-up, the patient's facial lesions achieved complete clinical remission.

Hidroacanthoma simplex (HS) is a rare skin appendage tumor that typically appears on the trunk and lower limbs in the elderly. Although HS is a predominantly benign condition, the presence of cellular atypia and dermal infiltration on histological examination indicates malignant HS (MHS). 5-aminolaevulinic acid photodynamic therapy (ALA-PDT) uses a photosensitizer and corresponding light source to cause irreversible damage or death of target cells through a photochemical reaction. Here, we reported the successful treatment of a MHS patient with ALA-PDT using plum-blossom needle pretreatment combined with CO2 laser. After five courses of ALA-PDT, the lesions were completely resolved, and the autonomic activity and smooth surface of the left ring finger were restored. This suggests that ALA-PDT is an effective, minimally invasive and safe treatment modality for MHS.

ObjectiveEndoscopic Zenker's diverticulotomy (EZD) is typically performed via stapling (endoscopic staple diverticulotomy; ESD) or CO2 laser (endoscopic laser diverticulotomy; ELD). Conflicting reports exist on which approach provides optimal outcomes. This investigation compared objective fluoroscopic data between ESD and ELD.MethodsA retrospective review of all patients undergoing primary EZD at a tertiary center between January 1, 2014 and January 10, 2022 was performed. Patients undergoing ESD and ELD were matched by preoperative diverticulum size. Primary outcome measures were postoperative diverticulum size and change in diverticulum size from pre- to postoperative swallowing fluoroscopy. Secondary outcome measures were the Eating Assessment Tool (EAT-10) score, penetration aspiration scale (PAS), pharyngeal constriction ratio (PCR), and pharyngoesophageal segment opening (PESo).ResultsThirteen matched pairs with complete fluoroscopic data were identified. The mean (±SD) age of the cohort was 74.0 (±8.5) years. There were no age or gender differences between groups (p > 0.05). The mean pre-operative ZD size was 1.98 (±0.69) cm for ESD and 1.97 (±0.72) cm for ELD; the mean postoperative size was 0.84 (±0.62) cm for ESD and 0.34 (±0.27) cm for ELD (p

This study explores the innovative use of CO2 laser technology in frenuloplasty, a significant shift from classic methods like scalpel surgery or electrocautery towards a minimally invasive approach. The research involved 15 patients aged 25 to 50, undergoing frenuloplasty with a CO2 laser system equipped with a 7-inch defocused handpiece, set at 20 Hz and 0.3 W. This method diverges from conventional laser techniques, focusing on controlled laser passes combined with manual traction to elongate the fibrous tissue of the frenulum. The results demonstrated that the CO2 laser technique allowed for a precise and progressive modification of the frenulum, significantly reducing the risks of hemorrhage and secondary intention fibrosis. The healing process was notably expedited, with patients reporting satisfactory outcomes within a two-week period. Statistically significant improvements were observed in patient-reported outcomes, as evidenced by the increases in the Short Form Health Survey (SF-12) scores, with the mean Physical Component Summary (PCS) score rising from 32.5 to 47.5 and the mean Mental Component Summary (MCS) score from 39.3 to 52.3 (p < 0.001 for both). The study concludes that CO2 laser frenuloplasty is an effective and safe technique, offering substantial benefits in terms of reduced healing time and enhanced patient satisfaction. The significant improvements in SF-12 scores underscore the positive impact on patient quality of life, advocating for the broader application of this technique in clinical practice. Further research is warranted to explore its potential in a wider clinical context.

Aim:: This study aims to compare the efficacy of CO2 fractionated laser therapy and topical estrogen treatment in managing Genitourinary Syndrome of Menopause (GSM). Materials and Methods:: A total of 88 patients diagnosed with GSM were included in this retrospective study. Of these, 39 received CO2 fractionated laser treatment, while 49 were treated with topical estrogen. Patients whose treatment was completed 1 to 1.5 months prior and had pre-treatment Vaginal Health Index (VHI) and International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) scored recorded were included in the study. These patients were invited for a follow-up visit, during which post-treatment VHI and ICIQ-SF scores were assessed by a physician. Results:: Both the laser and estrogen groups showed significant improvements in VHI and ICIQ-SF scores after treatment (p < 0.00001 for both groups). No statistically significant difference was found between the post-treatment VHI and ICIQ-SF scores of the two groups (p < 0.923 and p < 0.579, respectively). Conclusion:: Although there was no significant difference in the treatment efficacy between estrogen and CO2 fractionated laser therapy, there was a considerable difference in cost, with CO2 fractionated, with laser treatment being 23–24 times more expensive. Therefore, CO2 fractionated laser therapy, which shows similar short-term efficacy to topical estrogen, may be more suitable for patients where hormone therapy is contraindicated.

Simple Summary: In this study, we compared the outcomes of surgery for nasopharyngeal tumors in dogs using a conventional scalpel blade and a CO2 surgical laser system. We aimed to evaluate surgical time, bleeding level, patient pain, healing time, scar tissue formation, tumor relapse, and complications. We conducted a clinical prospective study involving 12 inpatient dogs, with 6 undergoing surgeries with a scalpel blade and 6 with a CO2 laser. We found that surgery using the CO2 laser resulted in shorter surgical and healing times, lower pain levels, less scar tissue formation, and a lower rate of tumor relapse compared to scalpel blade surgery. Our findings suggest that using the CO2 laser for nasopharyngeal tumor surgery may offer advantages in terms of precision, reduced discomfort, and fewer complications. We aimed to compare surgical time, bleeding level, patient pain level, healing period, scar tissue, relapse of the initial process and complications in patients with nasopharyngeal oncological masses undergoing surgery using a scalpel blade versus a CO2 surgical laser. This is a clinical prospective study comprising surgical work in the nasopharynx area. A sample of 12 inpatients dogs (N = 12) of both genders underwent a surgical excision of nasopharyngeal masses with a scalpel blade (GS n = 6) and CO2 surgical laser (GL n = 6). An Aesculigth CO2 surgical laser-Vetscalpel® model with a superpulse mode, 12 W of power, and a multi-focus pen was used. Statistically significant differences were registered for a p-value of < 0.05. Variations were noted between both groups (GS and GL) concerning surgery time (p = 0.038), first meal time (p = 0.013), pain level (p = 0.003), and healing time (p = 0.014), with the GL group presenting lower values. GL exhibited only one relapse case, with the elapsed time being more than double that of the GS group. Surgical and healing times were shorter in the GL group, and pain levels were lower, with the GL group also demonstrating less scar tissue than the GS group, along with a lower relapse rate. Nasopharynx surgical exposure with precision via the soft palate using the CO2 laser has facilitated successful treatment of regional masses without discomfort and complications, compared to conventional blade scalpel procedures. [ABSTRACT FROM AUTHOR]

Lasers are based on the principle of light amplification by empowering atoms to store and emit light in a coherent form. Through their effect on tissues, lasers reduce hemorrhage allowing the surgeon to work in a clear field with precise removal of the tissues. Irradiation of the soft tissues by lasers produces thermal effects on the surrounding healthy tissues which can make histopathological examination difficult. Hence this study was done to find a correlation between adjustable parameters of CO2 laser and the extent of collateral thermal damage in the excised vocal cord lesions on histopathological examination and diagnosis. In this study, we enrolled 80 patients who were divided into 4 groups with different combinations of laser power and mode, used during transoral laser micro laryngeal surgery for the excision of vocal cord lesions and subsequent histopathological analysis to objectively measure the extent of thermal damage zone and subjectively assess histo-morphological effects of thermal damage in terms of grade of carbonization. The extent of the thermal damage zone is directly related to the power of the laser, but the mode of the laser had no relation with the thermal damage zone in our study. On subjective histo-morphological examination of excised lesions showed that both power and mode of laser have significant effects on tissue morphology. Continuous mode causes a significantly higher grade of carbonization as compared to the superpulsed mode of the laser. However, in our study it was seen that charring in no way affected the diagnosis in any of the biopsies examined whatever the power or mode of the laser used. The depth and width of the tissue thermal damage zone are mainly dependent upon the laser parameters (power and mode). Although considering the limitations of this study carried out in terms of sample size, it would be pertinent to mention here that further studies with larger cohorts need to be done to authenticate these results. [ABSTRACT FROM AUTHOR]

This study explores the innovative use of CO2 laser technology in frenuloplasty, a significant shift from classic methods like scalpel surgery or electrocautery towards a minimally invasive approach. The research involved 15 patients aged 25 to 50, undergoing frenuloplasty with a CO2 laser system equipped with a 7-inch defocused handpiece, set at 20 Hz and 0.3 W. This method diverges from conventional laser techniques, focusing on controlled laser passes combined with manual traction to elongate the fibrous tissue of the frenulum. The results demonstrated that the CO2 laser technique allowed for a precise and progressive modification of the frenulum, significantly reducing the risks of hemorrhage and secondary intention fibrosis. The healing process was notably expedited, with patients reporting satisfactory outcomes within a two-week period. Statistically significant improvements were observed in patient-reported outcomes, as evidenced by the increases in the Short Form Health Survey (SF-12) scores, with the mean Physical Component Summary (PCS) score rising from 32.5 to 47.5 and the mean Mental Component Summary (MCS) score from 39.3 to 52.3 (p < 0.001 for both). The study concludes that CO2 laser frenuloplasty is an effective and safe technique, offering substantial benefits in terms of reduced healing time and enhanced patient satisfaction. The significant improvements in SF-12 scores underscore the positive impact on patient quality of life, advocating for the broader application of this technique in clinical practice. Further research is warranted to explore its potential in a wider clinical context. [ABSTRACT FROM AUTHOR]

Objectives: This study aimed to compare the effectiveness of carbon dioxide (CO2) laser vaporisation versus intralesional injection of triamcinolone acetonide (TA) in the management of oral lichen planus (OLP). Methods: A randomised clinical trial with a split‐mouth design was conducted on 16 patients with bilateral symptomatic OLP lesions. One side was treated with CO2 laser vaporisation, and the counterpart was treated with TA intralesional injection. The reticular–erythematous–ulcerative (REU) score, Thongprasom sign scoring (TSS), visual analogue scale (VAS) and lesion area were used to evaluate the lesions at weeks 0, 4 and 9. All participants were followed up for 9 months. Results: Reduction in the REU, TSS scores and lesion area from baseline to the end of treatment was significantly greater in the CO2 group than in the TA group (p values were 0.001, 0.002 and 0.048 respectively). However, the reduction in VAS score did not differ between the two groups (p = 0.54). The recurrence rate was significantly higher in the TA group than in the CO2 group (75% vs. 31.1%; p = 0.016). Conclusions: CO2 laser vaporisation was more effective than TA intralesional injection in managing OLP and decreased recurrence rates. [ABSTRACT FROM AUTHOR]

Objective: This in vitro study evaluates the shear bond strength (SBS) of yttria-stabilized tetragonal zirconia (Y-TZP) and resin cement after different surface treatments. Materials and methods: Forty-eight ceramic cubes were divided into four groups (n = 12): G1 (control) sandblasting with Al2O3; G2--sandblasting with silica-coated Al2O3 (Rocatec); G3--Rocatec + CO2 laser; and G4--CO2 laser + Rocatec. A metallic primer was applied to the pretreated ceramic. A rubber ring was adapted on the central area, and then, the resin cement was inserted into the matrix and photoactivated. The samples were evaluated regarding surface roughness (Ra), SBS, failure type, and qualitatively with scanning electron microscopy (SEM). The data were analyzed by one-way analysis of variance followed by Tukey's test (p < 0.05). Results: The mean values of Ra (lm) were as follows: G1--4.52a, G2--4.24a,b, G3--4.10a,b, and G4--2.90b and the mean values of SBS (MPa) were as follows: G1--7.84a, G2--4.41b, G3--4.61b and G4--6.14a,b. SEM analyses showed superficial irregularities for all groups, being more prominent for G1. The presence of silica deposits was observed for G2, G3, and G4, but in the last two groups there were some linear areas, promoted by the fusion of silica, due to the thermomechanical action of the CO2 laser. Conclusions: The surface treatment with CO2 laser + Rocatec, using one MDP-based cement, can be an alternative protocol for the adhesion cementation of Y-TZP ceramic since it was as effective as the conventional pretreatment with aluminum oxide sandblasting. [ABSTRACT FROM AUTHOR]

The skin contraction phenomenon occurs due to the energy emitted by the surgical CO2 LASER affecting the collagen architecture and intracellular water content in tissues. The study aimed to assess how gender, age, breed, body-weight, CO2 LASER emission mode, and potency influence skin contraction following the incision. The study involved 80 dogs (N = 80) of both genders, multiple breeds, undergoing major surgery with CO2 LASER. Subjects were grouped based on LASER potency (12 or 15 Watts) and emission mode (Superpulse—SP or Continuous—CT): GSP12, GSP15, GCT12, and GCT15. A 10 mm incision was performed using the surgical CO2 LASER beam, consistently employing a focal point of 0.4 mm, positioned at a distance of 1 mm from the skin surface, and always maintained perpendicular to it, and resulting lengths measured with a digital caliper. Results were considered significant for p-value < 0.05. GSP12 showed minimal contraction, while GCT15 exhibited the most significant. Male subjects in GCT12, GCT15, and GSP12 experienced less contraction than females. Purebred dogs had greater contraction than mixed breeds. GSP12 individuals showed age-related contraction decrease (p < 0.01), with skin contracting by 0.09 mm per year. Weight and skin contraction trended towards significance (p = 0.06), with a 0.02 mm increase per unit weight. For a constant power of 12 W, the analysis of the relationship between the emission mode of the LASER beam and the final skin contraction (GSP12 vs. GCT12) revealed statistically significant differences (p < 0.01). This study suggests that the use of the Continuous mode of LASER emission, regardless of the power used, is associated with a higher level of final skin contraction. Trial registration number and date of registration for prospectively registered trials: Project approval registration number by the Research and Teaching Ethics Committee (CEIE),Faculty of Veterinary Medicine—University of Lisbon (FMV_ULisboa), Lisboa—Portugal, N/Refª 015/2022. [ABSTRACT FROM AUTHOR]

Nasal mucosa tumors are an uncommon process and very dificult to work on with surgery. Radiotherapy associated or not with chemotherapy is the standard method to treat the disease. However, its access it is in the majority of the case not possible, making the surgery the best choice to try to achieve the patient's control. The anatomy of the region makes the complete surgical resection very difficult to achieve using the common and conventional blade scalpel surgery. The study features the advantages of using a CO2 laser to perform nasal mucosa carcinoma surgery in 6 dogs (N = 6). For the work we used an Aesculigth CO2 surgical laser model -Vetscalpel®, with the settings of 12Watts in a Superpulse mode, and a 0.25–0.4 mm focus to dissect the nasal mucosa, and a 1.5 mm focus for vaporization of the area. All the masses were histopathologically characterized as squamous cells carcinoma. The CO2 surgical laser allow us to work in a bloodless region promoting a more accurate dissection of the nasal mucosa sparing therefore the underlying and adjacent tissues and being less invasive. Also, it was possible to do the vaporization of the entire surgical area interviened. None of the patients presented relapse of clinical signs. Only 2 individuals were alive at the end of the study, presenting a survival rate of 420 and 514 days, which is in the same line of literature results of the treatment with radiotherapy combined with chemotherapy wich shows a median of 474–580 days. The study demonstrates successful outcomes with CO2 laser surgery in treating nasal mucosa SCC in dogs, with patients experiencing improved survival rates compared to traditional treatment methods. This highlights the efficacy and potential of CO2 laser surgery as a valuable tool in managing aggressive nasal tumors in veterinary oncology. [ABSTRACT FROM AUTHOR]

Aim: To characterize the effects of CO2 laser treatment and estrogen treatment on vaginal microbiota in patients with genitourinary syndrome of menopause (GSM). Methods: Sixty‐four patients with genitourinary syndrome were divided into the estrogen group, the CO2 laser group, and the control group. The control group did not receive any treatment. Vaginal mucosa was collected after 3 and 12 months of treatment. The former was used for 16S rRNA sequencing, and the latter was used for pathological evaluation. Vaginal health and voiding function were assessed using the vaginal health index (VHI) scale and the UDI‐6 scale at 3 and 12 months after treatment. Results: The results showed that both treatments reduced alpha diversity in the vaginal flora. Additionally, the abundance of 65 genera differed significantly between the treatment and control groups, with an increase in potentially beneficial bacteria such as Lactobacillus, IheB3_7, Mycoplasma urealyticum, and Streptococcus. In addition, the VHI and UDI‐6 scores improved in both treatment groups compared to the control group after 3 months. Whereas VHI and UDI‐6 scores were close to baseline in the estrogen group, and remained significantly improved in the CO2 laser group after 12 months. Pathological results showed that both methods improved the vaginal health status of patients with GSM after 12 months of treatment. However, the CO2 group exhibited a more significant increase in type III collagen. Conclusions: Both CO2 laser and estrogen therapies can regulate the vaginal flora imbalance of GSM and improve the corresponding symptoms. However, the long‐term efficacy of CO2 laser therapy is superior compared to estrogen therapy. [ABSTRACT FROM AUTHOR]

AISI 316L stainless steel lattices were manufactured using two distinct Laser Powder Bed Fusion (LPBF) techniques: a commercial printer equipped with a fiber laser and a novel system equipped with a CO2 laser. Fiber laser systems produce parts exhibiting superior detail, finer cell size, and lower porosity compared to CO2 laser ones because of the stability of the laser beam and the higher absorptivity of the laser light by the material powder. Electrochemical tests indicated that lattices exhibited inferior corrosion resistance compared to solid counterparts for both manufacturing techniques. This disparity is caused by the distinct corrosion mechanisms exhibited by lattices and solid parts, as observed through Electrochemical Impedance Spectroscopy (EIS). The observed differences are attributed not only to the increased different specific surface areas but also to the distinctive morphologies formed in the material beneath the surface. CO2 LPBF lattices demonstrated higher corrosion sensitivity than the fiber LPBF lattices due to their distinct microstructure and the more prevalent presence of defects.

Introduction: Atrophic acne scarring, a common sequela of acne, can be treated by different interventions, including microneedling and laser resurfacing. Objectives: We sought to evaluate the comparative efficacy of microneedling versus fractional CO2 laser in treating atrophic acne facial scars using clinical outcomes and imaging with high and ultra-high frequency ultrasound. Methods: Participants received 2 sessions, separated by 1 month, of microneedling on the left side of the face and fractional CO2 laser on the right. Clinical and color Doppler ultrasound evaluations (24 and 70 MHz) were conducted at baseline and 3 months after treatment. Each patient completed questionnaires on satisfaction, pain, and adverse effects. Results: Nine subjects were enrolled. The frequency order of scar types was boxcar, ice pick, and rolling. At 3 months, a decrease in scar scores was observed for total scars using ECCA scale (p= 0,0005), ice pick scars (p= 0.0128), and rolling scars (p= 0.0007). Both treatments were rated as good or very good by patient assessments. There was a low frequency of pain and hyperpigmentation reported with both modalities, albeit somewhat higher with microneedling. Twenty-two scars analyzed by ultrasound demonstrated a trend to decrease in size; however, no significant changes were observed for either microneedling or CO2 laser treatments. Moreover, there were no significant differences between these methods. Conclusion: Both microneedling and CO2 laser improved atrophic acne scars. Ultrasound did not show significant differences between these modalities.

PurposeTo explore the efficiency and safety of carbon dioxide (CO2) laser-assisted sclerectomy surgery (CLASS) in Chinese patients with glaucoma secondary to vitrectomy.MethodsThis retrospective study consisted of 16 eyes from 16 patients with glaucoma secondary to vitrectomy who underwent CLASS and were followed up for 12 months. Main outcome measures included preoperative and postoperative intraocular pressure, best corrected visual acuity (BCVA), number of anti-glaucoma medications, and postoperative surgical success rate and complications.ResultsThe postoperative IOP and number of anti-glaucoma medications used at all follow-up time point were significantly lower than those preoperatively. The difference in BCVA was not significant before and after surgery. The main complicatios were peripheral anterior synechiae (PAS) and scleral reservoir reduction, which were controlled after neodymium-doped yttrium aluminum garnet (Nd:YAG) laser, 2 (12.50%) patients underwent re-operation. The complete and total success rates at 12 months were 68.75% and 87.50%, respectively.ConclusionCLASS is a safe and effective procedure for Chinese patients with glaucoma secondary to vitrectomy. PAS and scleral reservoir reduction is a major contributor to postoperative IOP elevation, and trabecular minimally invasive perforation with the Nd:YAG laser is effective in lowering IOP and increasing scleral cistern volume.

Background/Aim: The aim of this study is to compare the impact of CO 2 laser on traditional zirconia and translucent zirconia in terms of the bonding strength to resin cement. Material and Methods: In this in-vitro study 20 zirconia disks (10 mm diameter and 2 mm thickness) were assigned to two groups (n = 10). Group 1: 10 discs of traditional zirconia, Group 2: 10 discs of translucent zirconia, CO 2 lasers were used for pretreatment of zirconia surface, respectively. Dentinal disks were cemented on zirconia disk using dual-curing resin cement. Shear bond strength tests were performed at a crosshead speed of 1 mm/min after 24 h distilled water storage. Data was analyzed by T Student's test. Results: The means and standard deviations of shear bond strength values in Group 1, and Group 2 were 1.15, 0.38, 1.99 , 0.65 MPa respectively. Data showed that application of CO 2 laser resulted in a significant higher shear bond strength of resin cement to translucent zirconia ceramics (p < 0.05). Conclusions: Application of CO 2 laser treatment (3W) increases the bond strength to the resin cement of translucent zirconia compared to traditional zirconia.

The fabrication of robust and high-performance graphene-based electrodes on engineering plastics has garnered significant attention in recent years. In this study, we present a novel methodology to produce porous graphene structures derived from epoxy resin (EP) utilizing a straightforward laser direct-scribing process. Under the influence of a CO2 laser in an ambient atmosphere, EP undergoes a transformation to yield laser-induced graphene (LIG-APP/EP). Furthermore, this LIG-APP/EP was employed to construct an electrode for lithium-ion batteries, which exhibited outstanding electrochemical performance. Notably, the initial charge and discharge capacities of the LIG-APP/EP electrode material were recorded at 976 and 1,452 mAh g−1, respectively, with a coulombic efficiency of 67.2%. Such impressive performance can be ascribed to the hierarchical porous architecture of LIG-APP/EP and the concurrent doping with nitrogen (N) and phosphorus (P) atoms. Given these findings, LIG-APP/EP demonstrates significant potential for applications in advanced electrochemical systems. This innovative approach also offers profound implications for the sustainable recycling of discarded engineering plastics.