1. Impact of facial and truncal acne on quality of life: A multi-country population-based survey
- Author
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Rajeev Chavda, Marco Rocha, Edward Lain, Stefan Beissert, Julie C Harper, Alison M. Layton, Adelaide A. Hebert, Jerry Tan, Jonathan M. Weiss, Fran Cook-Bolden, and Brigitte Dréno
- Subjects
HRQoL, health-related quality of life ,medicine.medical_specialty ,Dermatology ,CompAQ ,F, facial acne only ,Quality of life ,CDLQI, children's dermatology life quality index ,Surveys and Questionnaires ,Humans ,Medicine ,Patient Reported Outcome Measures ,CompAQ, Comprehensive Acne Quality of Life ,Population based survey ,Acne ,business.industry ,truncal acne ,dermatology life quality index (DLQI) ,Dermatology Life Quality Index ,Odds ratio ,medicine.disease ,humanities ,Confidence interval ,F+T, combined facial and truncal acne ,facial acne ,CI, confidence interval ,OR, odds ratio ,DLQI, dermatology life quality index ,quality of life ,patient-reported outcomes ,Original Article ,business ,Psychosocial ,Multi country - Abstract
Background Acne confers an increased risk of physical, psychiatric, and psychosocial sequelae, potentially affecting multiple dimensions of health-related quality of life (HRQoL). Morbidity associated with truncal acne is poorly understood. Objective To determine how severity and location of acne lesions impact the HRQoL of those who suffer from it. Methods A total of 694 subjects with combined facial and truncal acne (F+T) and 615 with facial acne only (F) participated in an online, international survey. Participants self-graded the severity of their acne at different anatomical locations and completed the dermatology life quality index (DLQI). Results The F+T participants were twice as likely to report "very large" to "extremely large" impact on HRQoL (ie, DLQI > 10 and children's DLQI [CDLQI] > 12) as compared with the F participants (DLQI: odds ratio [OR] 1.61 [95% confidence interval {CI} 1.02-2.54]; CDLQI: OR 1.86 [95% CI 1.10-3.14]). The impact of acne on HRQoL increased with increasing acne severity on the face (DLQI and CDLQI P values = .001 and .017, respectively), chest (P = .003; P = .008), and back (P = .001; P = .028). Limitations Temporal evaluation of acne impact was not estimated. Conclusions Facial and truncal acne was associated with a greater impact on HRQoL than facial acne alone. Increasing severity of truncal acne increases the adverse impact on HRQoL irrespective of the severity of facial acne.
- Published
- 2021