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346 results on '"CASULA, G"'

9. A nationwide audit of the use of radiotherapy for rectal cancer in Italy

Author

Gagliardi, G., Pucciarelli, S., Asteria, C. R., Infantino, A., Romano, G., Cola, B., De Nardi, P., Brulatti, M., Lambertini, M., Contessini-Avesani, E., Casula, G., Coco, C., D’Amico, D., Selvaggi, F. F., Eccher, C., D’Ambrosio, G., Galeotti, F., Jovine, E., Demma, I., Fianchini, A., Ambrosino, G., Casentino, L. M., and Fiorino, M.

Published
2010
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24. MUTYH-associated colon disease: Adenomatous polyposis is only one of the possible phenotypes. A family report and literature review

Author

Luigi Zorcolo, Fantola, G., Balestrino, L., Restivo, A., Vivanet, C., Spina, F., Cabras, F., Ambu, R., and Casula, G.

Subjects
Adult, Male, Cancer Research, Hyperplasia, Lymphoid Tissue, Genetic Counseling, Colonoscopy, Syndrome, General Medicine, Middle Aged, DNA Glycosylases, 030218 nuclear medicine & medical imaging, Primary Prevention, 03 medical and health sciences, Phenotype, 0302 clinical medicine, Adenomatous Polyposis Coli, Oncology, 030220 oncology & carcinogenesis, Colonic Neoplasms, Mutation, Humans, Genetic Predisposition to Disease, Genetic Testing
Abstract

Aims and background The MutY human homologue gene (MUTYH) is responsible for about a quarter of attenuated familial adenomatous polyposis. Occasionally, it has been associated with hyperplastic polyps and serrated adenoma. We report a family where the same MUTYH mutation determined four different phenotypes, including a case of hyperplastic polyposis syndrome. Patients and methods A family with a history of right-sided colon cancer and multiple colonic polyposis was investigated. Genetic tests were correlated with clinical findings to define phenotypic manifestations of MUTYH mutations. The pertinent English-language literature was reviewed to evaluate the risk of malignancy of MUTYH and the role of prophylactic surgery. Results Three male siblings carried a biallelic MUTYH mutation (G382D-exon13), while the fourth was heterozygote. One developed an isolated cecal cancer at the age of 48. Another, aged 38, was diagnosed with numerous minute colonic and rectal polyps and underwent a proctocolectomy, with final pathology showing a picture of hyperplastic and lymphoid polyposis. The third biallelic brother, 46 years old, developed four hyperplastic lesions, while the heterozygote brother had a large flat serrated adenoma of the right colon removed at the age of 50. Conclusion Many aspects of MUTYH mutation still need to be clarified and one of them regards the different phenotypic expressions. Although the majority of reported cases manifested attenuated adenomatous polyposis, hyperplastic polyps and serrated adenomas appear to be more common than expected. Presenting hyperplastic polyposis syndrome is very unusual and may represent a clinical dilemma for correct management. Current evidence suggests to handle MUTYH-associated polyposis as typical FAP.

Published
2011

28. Vertical and horizontal crustal movements in Central and Northern Italy

Author

BALDI, PAOLO, BACCHETTI, MASSIMO, Casula G., Cenni N., Loddo F., Pesci A., Baldi P., Casula G., Cenni N., Loddo F., Pesci A., and Bacchetti M.

Subjects
ITALIA, central and northern Apennines, GPS network, DEFORMAZIONI, GPS, GPS network, velocity field, central and northern Apennines, velocity field, TETTONICA
Abstract

Descrizione del campo di deformazione nell'Italia centro-settentrionale desunto dall'analisi di dati di stazioni GPS permanenti.

Published
2011

30. An experiment for ZSCAN efficiency in surface monitoring

Author

Pesci A., Loddo F., Casula G., Ceccaroni F., Bianchini D., Menci L., BALDI, PAOLO, INGV, Pesci A., Loddo F., Casula G., Ceccaroni F., Bianchini D., Baldi P., and Menci L.

Subjects
CRUSTAL DEFORMATION, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, PHOTOGRAMMETRY, DIGITALL MODELS
Abstract

ZSCAN is an innovative and complete measurement system for the accurate acquisition and management of point clouds. It is composed of a photogrammetric device with one or more calibrated cameras installed on a mechanical apparatus.....

Published
2009

32. Data analysis of permanent GPS networks in Italy and surrounding regions:application of a distributed processing approach

Author

Serpelloni E., Casula G., Galvani A., Anzidei M., BALDI, PAOLO, Serpelloni E., Casula G., Galvani A., Anzidei M., and Baldi P.

Subjects
DEFORMAZIONI, GPS, TETTONICA
Abstract

The procedures used to combine into a uniform velocity solution the observations of more than 80 continuous GPS stations operating in the central Mediterranean in the 1998-2004 time interval. are described

Published
2006

39. A new gps permanent network in the northern apennines: first results

Author

Cenni, N., Albarello, D., Babbucci, D., Baldi, P., Casula, G., Ferrini, M., Loddo, F., Mantovani, E., Pesci, A., Viti, M., INTERNATIONAL UNION OF GEOLOGICAL SCIENCES, Cenni N., Albarello D., Babbucci D., Baldi P., Casula G., Ferrini M., Loddo F., Mantovani E., Pesci A., and Viti M.

Subjects
STRAIN, NEOTECTONIC, GPS
Abstract

This study provides information on the velocity and strain fields of the principal seismogenetic zones of Toscana region.

Published
2004

40. Innovative Surveying and Monitoring Approaches to Geomorphological Processes Detection

Author

MORA, PAOLO, BALDI, PAOLO, GHIROTTI, MONICA, BACCHETTI, MASSIMO, Bedin A., Casula G., Cenni N., Fabris M., Loddo F., Pesci A., Mora P., Baldi P., Bedin A., Casula G., Cenni N., Fabris M., Ghirotti M., Loddo F., Pesci A., and Bacchetti M.

Subjects
LASER SCANNING, PHOTOGRAMMETRY, GEOMORPHOLOGY, GLOBAL POSITIONING SYSTEM - GPS
Published
2004

42. Emerging technologies in coloproctology: results of the Italian Society of Colorectal Surgery Logbook of Adverse Events

Author

Group study members: Altomare DF, Aeco, Amato, A, Basso, L, Bianco, V, Binda, G, Boffi, F, Bottini, C, Carrino, F, Casula, G, Cavicchi, A, Codacci Pisanelli, M, De Nardi, P, Destefano, I, Dodi, G, Fucini, C, Gaj, F, Gentile, M, Iachino, C, Indinnimeo, M, Infantino, A, La Torre, F, Mancini, S, Mattana, C, Nemati Fard, M, Pescatori, M, Pietroletti, R, Pulvirenti D’Urso, A, Rinaldi, M, Ripetti, V, Spinelli, F, Tricomi, N, Veronesi, P, and Zorcolo, L.

Subjects
Adult, Male, Reoperation, medicine.medical_specialty, Pathology, Emerging technologies, Events, Biomedical Technology, Adverse, Emerging, Technologies, Coloproctology, Young Adult, Medical, Humans, Medicine, Adverse effect, Digestive System Surgical Procedures, Societies, Medical, Aged, business.industry, General surgery, Colorectal Surgery, Female, Italy, Middle Aged, Surgery, Gastroenterology, Colorectal surgery, Societies, business, Logbook, emerging technologies in coloproctology
Abstract

The aim of this paper is to present the results of the Italian Society of Colorectal Surgery [or Società Italiana di Chirurgia Colorettale (SICCR)] Logbook of adverse events (AE) occurring in relation to emerging technologies in coloproctology (ETCs), over a 3-year period.A total of 245 AE were reported (patients age: mean = 49.6 years, range = 20-75 years; gender: 155 = F, 90 = M). The "observations" originated from the same institution of the AEs in 44 cases (18.0%), while 201 patients (82.0%) had been operated on somewhere else.The three most reported ETCs were: Procedure for prolapsed haemorrhoids (PPH) (n = 120-48.9%), stapled transanal rectal resection (STARR (n = 96-39.2%), and transanal haemorrhoidal dearterialization (THD) (n = 11-4.5%). PPH, STARR, and THD together accounted for n = 227 (92.6%) observations. For the three main reported ETCs, the various AEs are listed. Chronic pain after PPH was 46/120 (38.3%), and after STARR of 21/96 (21.9%). The overall re-operation rate was n = 135 (55.1%) versus n = 110 (44.9%) no reoperation. In particular, for the three main reported ETCs, n = 68/120 (56.7%) following an AE after PPH, n = 47/94 (50.0%) following an AE after STARR, and n = 6/11 (54.5) following an AE post-THD. The various types of treatment to solve AE after each of the three most observed ETCs are reported in the text.Our results do not allow us to draw statistical conclusions; however, this was not the aim of our survey. ETCs are important, yet they are not without major risks. Manufacturers should help colorectal surgeons to convey the right message to patients.

Published
2013

44. Ultralow Voltage, OTFT-Based Sensor for Label-Free DNA Detection

Author

Lai, S. [ 1 ], Demelas M. [ 1, 2 ], Casula G. [ 1, Cosseddu P. [ 1, Barbaro M. [ 1 ], and Bonfiglio A. [ 1

Subjects
Detection limit, Materials science, Organic field-effect transistor, Transistors, Electronic, Oligonucleotide, business.industry, Mechanical Engineering, Electric Conductivity, organic chemosensor, organic field effect transistor, organic biosensor, DNA hybridization sensor, ultra-low voltage device, Nucleic Acid Hybridization, DNA, Electric charge, Transduction (genetics), Electricity, Mechanics of Materials, Optoelectronics, General Materials Science, Field-effect transistor, Organic Chemicals, business, Selectivity, Voltage
Abstract

An organic ultralow voltage field effect transistor for DNA hybridization detection is presented. The transduction mechanism is based on a field-effect modulation due to the electrical charge of the oligonucleotides, so label-free detection can be performed. The device shows a sub-nanometer detection limit and unprecedented selectivity with respect to single nucleotide polymorphism.

Published
2013

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