228 results on '"CANDAN, Cengiz"'
Search Results
2. Timing and Modality of Kidney Replacement Therapy in Children and Adolescents
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Cortina, G., Arbeiter, K., Dusek, J., Harambat, J., Ranchin, B., Fischbach, M., Querfeld, U., Habbig, S., Galiano, M., Büscher, R., Gimpel, C., Kemper, M., Melk, A., Thurn, D., Schaefer, F., Doyon, A., Wühl, E., Pohl, M., Wygoda, S., Jeck, N., Kranz, B., Wigger, M., Montini, G., Lugani, F., Testa, S., Vidal, E., Matteucci, C., Picca, S., Jankauskiene, A., Azukaitis, K., Zurowska, A., Drodz, D., Tkaczyk, M., Urasinski, T., Litwin, M., Szczepanska, M., Texeira, A., Peco-Antic, A., Bucher, B., Laube, G., Anarat, A., Bayazit, A.K., Yalcinkaya, F., Basin, E., Cakar, N., Soylemezoglu, O., Duzova, A., Bilginer, Y., Erdogan, H., Donmez, O., Balat, A., Kiyak, A., Caliskan, S., Canpolat, N., Candan, C., Civilibal, M., Emre, S., Ozcelik, G., Mir, S., Sözeri, B., Yavascan, O., Tabel, Y., Ertan, P., Yilmaz, E., Shroff, R., Thumfart, Julia, Wagner, Steffen, Kirchner, Marietta, Azukaitis, Karolis, Bayazit, Aysun K., Obrycki, Lukasz, Canpolat, Nur, Bulut, Ipek Kaplan, Duzova, Ali, Anarat, Ali, Bessenay, Lucie, Shroff, Rukshana, Paripovic, Dusan, Sever, Lale, Candan, Cengiz, Lugani, Francesca, Yilmaz, Alev, Yalcinkaya, Fatos, Arbeiter, Klaus, Kiyak, Aysel, Zurowska, Aleksandra, Galiano, Matthias, Querfeld, Uwe, Melk, Anette, and Schaefer, Franz
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- 2024
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3. Long-term Effects of Kidney Transplantation Compared With Dialysis on Intima–media Thickness in Children—Results From the 4C-T Study
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Grabitz, Carl, Sugianto, Rizky I., Doyon, Anke, Azukaitis, Karolis, Anarat, Ali, Bacchetta, Justine, Bayazit, Aysun K., Bulut, Ipek K., Caliskan, Salim, Canpolat, Nur, Duzova, Ali, Habbig, Sandra, Harambat, Jerome, Kiyak, Aysel, Longo, Germana, Obrycki, Lukasz, Paripovic, Dusan, Söylemezoğlu, Oğuz, Thurn-Valsassina, Daniela, Yilmaz, Alev, Shroff, Rukshana, Schaefer, Franz, Schmidt, Bernhard M.W., Melk, Anette, Cortina, Gerard, Arbeiter, Klaus, Dusek, Jiri, Harambat, Jerome, Ranchin, Bruno, Fischbach, Michel, Zaloszyc, Ariane, Querfeld, Uwe, Gellermann, Jutta, Habbig, Sandra, Liebau, Max, Galiano, Matthias, Büscher, Rainer, Gimpel, Charlotte, Kemper, Matthias, Oh, Jun, Melk, Anette, Thurn-Valassina, Daniela, Doyon, Anke, Wühl, Elke, Schaefer, Franz, John, Ulrike, Wygoda, Simone, Jeck, Nicola, Kranz, Birgitta, Wigger, Marianne, Mencarelli, Francesca, Lugani, Francesca, Testa, Sara, Montini, Giovanni, Morello, William, Vidal, Enrico, Benetti, Elisa, Murer, Luisa, Matteucci, Ciara, Picca, Stefano, Gesù, Ospedale Bambino, Jankauskiene, Augustina, Azukaitis, Karolis, Zurowska, Aleksandra, Zagozozon, Ilona, Drodz, Dorota, Urasinski, Tomasz, Litwin, Mieczyslaw, Niemirska, Anna, Obrycki, Lukasz, Szczepanska, Maria, Texeira, Ana, Peco-Antic, Amira, Paripovic, Dusan, Simonetti, Giacomo, Laube, Guido, Anarat, Ali, Bayazit, Aysun K., Yalcinkaya, Fatos, Baskin, Esra, Cakar, Nilgun, Soylemezoglu, Oguz, Duzova, Ali, Bilginer, Yelda, Erdogan, Hakan, Donmez, Osman, Balat, Ayse, Kiyak, Aysel, Caliskan, Salim, Canpolat, Nur, Civilibal, Mahmut, Candan, Cengiz, Emre, Sevinc, Yilmaz, Alev, Alpay, Harika, Ozcelik, Gul, Mir, Sevgi, Sözeri, Betul, Bulut, Ipek K., Aksu, Nejat, Yavascan, Onder, Tabel, Yilmaz, Ertan, Pelin, Yilmaz, Ebru, and Shroff, Rukshana
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- 2024
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4. Steroid-Resistant Nephrotic Syndrome due to NPHS2 Variants Is Not Associated With Posttransplant Recurrence
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Boutaba, Mounia, Csaiscich, Dagmar, Baiko, Sergay, Azocar, Marta, Quiroz, Lily, Serna Higuita, Lina Maria, Dušek, Jiří, Ranchin, Bruno, Zaloszyc, Adriane, Davitaia, Tinatin, Gellermann, Jutta, Oh, Jun, Melk, Anette, Schaefer, Franz, Staude, Hagen, Printza, Nikoleta, Tory, Kalman, Gheissari, Alaleh, Remuzzi, Giuseppe, Pasini, Andrea, Ghiggeri, Gian Marco, Ardissino, Gianluigi, Benetti, Elisa, Emma, Francesco, Camilla, Roberta, Nigmatullina, Nazym, Aoun, Bilal, Mourani, Chebl, Abou-Jaoudé, Pauline, Jankauskiene, Augustina, Wasilewska, Anna, Klekot, Lidia Hyla, Zurowska, Aleksandra, Drozdz, Dorota, Tkaczyk, Marcin, Sikora, Przemysław, Ostalska, Danuta, Brodkiewicz, Andrzej, Litwin, Mieczyslaw, Panczyk-Tomaszewska, Małgorzata, Medyńska, Anna, Szczepanska, Maria, Afonso, Alberto Caldas, Jardim, Helena, Lungu, Adrian, Tsygin, Alexej, Prikhodina, Larisa, Paripovic, Dusan, Bogdanovic, Radovan, Krmar, Rafael T., Saeed, Bassam, Anarat, Ali, Balat, Ayse, Baskin, Z. Esra, Cakar, Nilgun, Erdogan, Ozlem, Özcakar, Birsin, Ozaltin, Fatih, Sakallioglu, Onur, Soylemezoglu, Oguz, Akman, Sema, Gok, Faysal, Caliskan, Salim, Candan, Cengiz, Yilmaz, Alev, Sozeri, Betul, Akil, Ipek, Ertan, Pelin, Özkaya, Ozan, Kalyoncu, Mukaddes, Bitzan, Martin, Formina, Svitlana, Sobko, Roman, Kachmar, Jessica, Boyer, Olivia, Lipska-Ziętkiewicz, Beata, Morinière, Vincent, Gribouval, Olivier, Heidet, Laurence, Balasz-Chmielewska, Irena, Cloarec, Sylvie, Csaicsich, Dagmar, Decramer, Stéphane, Guigonis, Vincent, Hogan, Julien, Bayazit, Aysun Karabay, Tsimaratos, Michel, Trautmann, Agnes, Antignac, Corinne, and Dorval, Guillaume
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- 2024
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5. A case of chronic kidney disease with pulmonary hypertension, hyperuricemia, immunodeficiency and other extrarenal findings: Answers
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Göknar, Nilüfer, Keleşoğlu, Emre, Kasap, Nurhan, Üçkardeş, Diana, and Candan, Cengiz
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- 2022
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6. Timing and modality of kidney replacement therapy in children and adolescents
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Thumfart, Julia, primary, Wagner, Steffen, additional, Kirchner, Marietta, additional, Azukaitis, Karolis, additional, Bayazit, Aysun K., additional, Obrycki, Lukasz, additional, Canpolat, Nur, additional, Bulut, Ipek Kaplan, additional, Duzova, Ali, additional, Anarat, Ali, additional, Bessenay, Lucie, additional, Shroff, Rukshana, additional, Paripovic, Dusan, additional, Sever, Lale, additional, Candan, Cengiz, additional, Lugani, Francesca, additional, Yilmaz, Alev, additional, Yalcinkaya, Fatos, additional, Arbeiter, Klaus, additional, Kiyak, Aysel, additional, Zurowska, Aleksandra, additional, Galiano, Matthias, additional, Querfeld, Uwe, additional, Melk, Anette, additional, Schaefer, Franz, additional, Cortina, G., additional, Arbeiter, K., additional, Dusek, J., additional, Harambat, J., additional, Ranchin, B., additional, Fischbach, M., additional, Zalosczyk, A., additional, Querfeld, U., additional, Habbig, S., additional, Galiano, M., additional, Büscher, R., additional, Gimpel, C., additional, Kemper, M., additional, Melk, A., additional, Thurn, D., additional, Schaefer, F., additional, Doyon, A., additional, Wühl, E., additional, Pohl, M., additional, Wygoda, S., additional, Jeck, N., additional, Kranz, B., additional, Wigger, M., additional, Montini, G., additional, Lugani, F., additional, Testa, S., additional, Vidal, E., additional, Matteucci, C., additional, Picca, S., additional, Jankauskiene, A., additional, Azukaitis, K., additional, Zurowska, A., additional, Drodz, D., additional, Tkaczyk, M., additional, Urasinski, T., additional, Litwin, M., additional, Niemirska, A., additional, Szczepanska, M., additional, Texeira, A., additional, Peco-Antic, A., additional, Bucher, B., additional, Laube, G., additional, Anarat, A., additional, Bayazit, A.K., additional, Yalcinkaya, F., additional, Basin, E., additional, Cakar, N., additional, Soylemezoglu, O., additional, Duzova, A., additional, Bilginer, Y., additional, Erdogan, H., additional, Donmez, O., additional, Balat, A., additional, Kiyak, A., additional, Caliskan, S., additional, Canpolat, N., additional, Candan, C., additional, Civilibal, M., additional, Emre, S., additional, Alpay, H., additional, Ozcelik, G., additional, Mir, S., additional, Sözeri, B., additional, Yavascan, O., additional, Tabel, Y., additional, Ertan, P., additional, Yilmaz, E., additional, and Shroff, R., additional
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- 2024
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7. Refining genotype–phenotype correlations in 304 patients with autosomal recessive polycystic kidney disease and PKHD1 gene variants
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Eid, Loai Akram, Arbeiter, Klaus, Godefroid, Nathalie, Lombet, Jacques, De Mul, Aurélie, Feldkoetter, Markus, Zieg, Jakub, Grundmann, Franziska, Galiano, Matthias, Buchholz, Björn, Buescher, Anja, Häffner, Karsten, Gross, Oliver, Patzer, Ludwig, Oh, Jun, Haffner, Dieter, Bernhardt, Wanja, Schaefer, Susanne, Wygoda, Simone, Halbritter, Jan, Derichs, Ute, Klaus, Günter, Lechner, Felix, Ponsel, Sabine, König, Jens, Staude, Hagen, Wurm, Donald, Bald, Martin, Gessner, Michaela, Soliman, Neveen A., Ariceta, Gema, Gonzalez Rodriguez, Juan David, Ojeda, Francisco de la Cerda, Harambat, Jerome, Morin, Denis, Dossier, Claire, Dorval, Guillaume, Shroff, Rukshana, Stabouli, Stella, Hooman, Nakysa, Mencarelli, Francesca, Morello, William, Longo, Germana, Emma, Francesco, Jankauskiene, Augustina, Taranta-Janusz, Katarzyna, Zagozdzon, Ilona, Zachwieja, Katarzyna, Stanczyk, Malgorzata, Bienias, Beata, Litwin, Mieczyslaw, Morawiec-Knysak, Aurelia, Afonso, Alberto Caldas, Dunand, Oliver, Rachisan, Andreea, Miloševski-Lomić, Gordana, Papizh, Svetlana, Rus, Rina, Jilani, Houweyda, Atmis, Bahriye, Duzova, Ali, Soylu, Alper, Candan, Cengiz, Caliskan, Salim, Yilmaz, Alev, Gökce, İbrahim, Akinci, Nurver, Mir, Sevgi, Dursun, Ismail, Tabel, Yilmaz, Nalcacioglu, Hulya, Burgmaier, Kathrin, Brinker, Leonie, Erger, Florian, Beck, Bodo B., Benz, Marcus R., Bergmann, Carsten, Boyer, Olivia, Collard, Laure, Dafinger, Claudia, Fila, Marc, Kowalewska, Claudia, Lange-Sperandio, Bärbel, Massella, Laura, Mastrangelo, Antonio, Mekahli, Djalila, Miklaszewska, Monika, Ortiz-Bruechle, Nadina, Prikhodina, Larisa, Ranchin, Bruno, Ranguelov, Nadejda, Schild, Raphael, Seeman, Tomas, Sever, Lale, Sikora, Przemyslaw, Szczepanska, Maria, Teixeira, Ana, Thumfart, Julia, Uetz, Barbara, Weber, Lutz Thorsten, Wühl, Elke, Zerres, Klaus, Dötsch, Jörg, Schaefer, Franz, and Liebau, Max Christoph
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- 2021
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8. A case of chronic kidney disease with pulmonary hypertension, hyperuricemia, immunodeficiency and other extrarenal findings: Questions
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Göknar, Nilüfer, Keleşoğlu, Emre, Kasap, Nurhan, Üçkardeş, Diana, and Candan, Cengiz
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- 2022
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9. Outcome of immunosuppression in children with IgA vasculitis–related nephritis.
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Rohner, Katharina, Marlais, Matko, Ahn, Yo Han, Ali, Alaa, Alsharief, Abrar, Novak, Anja Blejc, Brambilla, Marta, Cakici, Evrim Kargin, Candan, Cengiz, Canpolat, Nur, Chan, Eugene Yu-hin, Decramer, Stéphane, Didsbury, Madeleine, Durao, Filipa, Durkan, Anne M, Düzova, Ali, Forbes, Thomas, Gracchi, Valentina, Güngör, Tulin, and Horinouchi, Tomoko
- Subjects
PROGNOSIS ,SYMPTOMS ,PEDIATRIC nephrology ,GLOMERULAR filtration rate ,CHRONIC kidney failure - Abstract
Background Immunoglobulin A vasculitis with nephritis (IgAVN) is the most common vasculitis in children. Due to a lack of evidence, treatment recommendations are based on expert opinion, resulting in variation. The aim of this study was to describe the clinical presentation, treatment and outcome of an extremely large cohort of children with biopsy-proven IgAVN in order to identify prognostic risk factors and signals of treatment efficacy. Methods Retrospective data were collected on 1148 children with biopsy-proven IgAVN between 2005 and 2019 from 41 international paediatric nephrology centres across 25 countries and analysed using multivariate analysis. The primary outcome was estimated glomerular filtration rate (eGFR) and persistent proteinuria at last follow-up. Results The median follow-up was 3.7 years (interquartile range 2–6.2). At last follow-up, 29% of patients had an eGFR <90 mL/min/1.73 m
2 , 36% had proteinuria and 3% had chronic kidney disease stage 4–5. Older age, lower eGFR at onset, hypertension and histological features of tubular atrophy and segmental sclerosis were predictors of poor outcome. There was no evidence to support any specific second-line immunosuppressive regimen being superior to others, even when further analysing subgroups of children with reduced kidney function, nephrotic syndrome or hypoalbuminemia at onset. Delayed start of immunosuppressive treatment was associated with a lower eGFR at last follow-up. Conclusion In this large retrospective cohort, key features associated with disease outcome are highlighted. Importantly, there was no evidence to support that any specific immunosuppressive treatments were superior to others. Further discovery science and well-conducted clinical trials are needed to define accurate treatment and improve outcomes of IgAVN. [ABSTRACT FROM AUTHOR]- Published
- 2024
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10. Pediatric kidney care experience after the 2023 Türkiye earthquake
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Bakkaloğlu, Sevcan A, primary, Delibaş, Ali, additional, Sürmeli Döven, Serra, additional, Taner, Sevgin, additional, Yavuz, Sevgi, additional, Erfidan, Gökçen, additional, Danacı Vatansever, Esra, additional, Aynacı, Fatma, additional, Yilmaz, Kenan, additional, Taşdemir, Mehmet, additional, Akacı, Okan, additional, Akıncı, Nurver, additional, Güven, Serçin, additional, Çiçek, Neslihan, additional, Dursun, Ismail, additional, Keleşoğlu, Emre, additional, Sancaktar, Muhammet, additional, Alaygut, Demet, additional, Saygılı, Seha, additional, Yavaşcan, Önder, additional, Yılmaz, Alev, additional, Gülleroğlu, Kaan, additional, Ertan, Pelin, additional, Demir, Belde Kasap, additional, Poyrazoğlu, Hakan, additional, Pınarbaşı, Seda, additional, Gençler, Aylin, additional, Baştuğ, Funda, additional, Günay, Neslihan, additional, Çeleğen, Kübra, additional, Noyan, Aytül, additional, Parmaksız, Gönül, additional, Avcı, Begüm, additional, Çaycı, Fatma Şemsa, additional, Bayrakçı, Umut, additional, Özlü, Sare Gülfem, additional, Aksoy, Özlem Yüksel, additional, Yel, Sibel, additional, İnal, Güldane Aylin, additional, Köse, Seçil, additional, Bayazıt, Aysun Karabay, additional, Atmış, Bahriye, additional, Sarıbaş, Emel, additional, Çağlı, Çağla, additional, Tabel, Yılmaz, additional, Elmas, Ahmet Taner, additional, Zırhlı Selçuk, Şenay, additional, Demircioğlu Kılıç, Beltinge, additional, Akbalık Kara, Mehtap, additional, Büyükçelik, Mithat, additional, Balat, Ayşe, additional, Durucu Tiryaki, Betül, additional, Erdoğdu, Bilge, additional, Aksu, Bağdagül, additional, Mahmudova, Günay, additional, Dursun, Hasan, additional, Candan, Cengiz, additional, Göknar, Nilüfer, additional, Mutlubaş, Fatma, additional, Çamlar, Seçil Arslansoyu, additional, Başaran, Cemaliye, additional, Akbulut, Burcu Bulum, additional, Düzova, Ali, additional, Gülhan, Bora, additional, Oruç, Çiğdem, additional, Peru, Harun, additional, Alpay, Harika, additional, Türkkan, Özde Nisa, additional, Gülmez, Rüveyda, additional, Çelakıl, Mehtap, additional, Doğan, Kenan, additional, Bilge, Ilmay, additional, Pehlivanoğlu, Cemile, additional, Büyükkaragöz, Bahar, additional, Leventoğlu, Emre, additional, Alpman, Nuray, additional, Zeybek, Cengiz, additional, Tülpar, Sebahat, additional, Çiçek Gülşan, Rümeysa Yasemin, additional, Kara, Aslıhan, additional, Gürgöze, Metin Kaya, additional, Akyol Önder, Esra Nagehan, additional, Özdemir Atikel, Yeşim, additional, Pul, Serim, additional, Sönmez, Ferah, additional, Yıldız, Gizem, additional, Akman, Sema, additional, Elmacı, Midhat, additional, Küçük, Nuran, additional, Yüksel, Selçuk, additional, Kavaz, Aslı, additional, Nalçacıoğlu, Hülya, additional, Alparslan, Caner, additional, Dinçel, Nida, additional, Elhan, Atilla H, additional, and Sever, Lale, additional
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- 2024
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11. COL4A3 mutation is an independent risk factor for poor prognosis in children with Alport syndrome
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Ozdemir, Gulsah, Gulhan, Bora, Atayar, Emine, Saygılı, Seha, Soylemezoglu, Oguz, Ozcakar, Zeynep Birsin, Eroglu, Fehime Kara, Candan, Cengiz, Demir, Belde Kasap, Soylu, Alper, Yüksel, Selçuk, Alpay, Harika, Agbas, Ayse, Duzova, Ali, Hayran, Mutlu, Ozaltin, Fatih, and Topaloglu, Rezan
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- 2020
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12. Low levels of urinary epidermal growth factor predict chronic kidney disease progression in children
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Arbeiter, Klaus, Rosales, Alejandra, Dusek, Jiri, Zaloszyc, Ariane, Querfeld, Uwe, Gellermann, Jutta, Liebau, Max, Weber, Lutz, Muschiol, Evelin, Büscher, Rainer, Oh, Jun, Melk, Anette, Thurn-Valassina, Daniela, Haffner, Dieter, Schaefer, Franz, Gimpel, Charlotte, John, Ulrike, Wygoda, Simone, Jeck, Nikola, Wigger, Marianne, Testa, Sara, Murer, Luisa, Matteucci, Chiara, Jankauskiene, Augustina, Azukaitis, Karolis, Drozdz, Dorota, Lugani, Francesca, Zurowska, Aleksandra, Zaniew, Marcin, Litwin, Mieczyslaw, Nimierska, Anna, Teixeira, Ana, Peco-Antic, Amira, Paripovic, Dusan, Laube, Guido, Anarat, Ali, Bayazit, Aysun, Duzova, Ali, Bilginer, Yelda, Caliskan, Salim, Canpolat, Nur, Civilibal, Mahmut, Mir, Sevgi, Sözeri, Betül, Kranz, Brigitta, Mencarelli, Francesca, Dorn, Brigitte, Yalcinkaya, Fatos, Baskin, Esra, Cakar, Nilgun, Soylemezoglu, Oguz, Emre, Sevinc, Candan, Cengiz, Kiyak, Aysel, Ozcelik, Gul, Alpay, Harika, Shroff, Rukshana, Rachin, Bruno, Harambat, Jerome, Szczepanska, Maria, Erdogan, Hakan, Donmez, Osman, Balat, Ayse, Aksu, Nejat, Tabel, Yilmaz, Ertan, Pelin, Yilmaz, Ebru, Bakkaloglu, Aysin, Ozaltin, Fatih, Sallay, Peter, Drożdż, Dorota, Bonzel, Klaus-Eugen, Wingen, Anna-Margrete, Żurowska, Aleksandra, Balasz, Irena, Trivelli, Antonella, Perfumo, Francesco, Müller-Wiefel, Dirk-Erhard, Möller, Kerstin, Offner, Gisela, Enke, Barbara, Wühl, Elke, Hadtstein, Charlotte, Mehls, Otto, Hohbach-Hohenfellner, Katharina, Jeck, Nickola, Klaus, Günter, Ardissino, Gianluigi, Montini, Giovanni, Charbit, Marina, Niaudet, Patrick, Afonso, Alberto Caldas, Fernandes-Teixeira, Ana, Dušek, Jiri, Picca, Stefano, Berg, Ulla B., Celsi, Giovanni, Fischbach, Michel, Terzic, Joelle, Fydryk, Janusz, Urasinski, Tomasz, Coppo, Rosanna, Peruzzi, Licia, Grenda, Ryszard, Neuhaus, Thomas J., Ju, Wenjun, Kirchner, Marietta, Nair, Viji, Smith, Michelle, Fang, Zhiyin, Thurn-Valsassina, Daniela, Niemirska, Anna, Bulut, Ipek Kaplan, Vidal, Enrico, Yavascan, Onder, and Kretzler, Matthias
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- 2019
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13. Risk Factors for Early Dialysis Dependency in Autosomal Recessive Polycystic Kidney Disease
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Ranguelov, Nadejda, Godefroid, Nathalie, Collard, Laure, Lombet, Jacques, Maquet, Julie, Schalk, Gesa, Querfeld, Uwe, Beck, Bodo B., Benzing, Thomas, Buettner, Reinhard, Grundmann, Franziska, Kurschat, Christine, Benz, Kerstin, Tzschoppe, Anja, Buchholz, Björn, Buescher, Rainer, Häffner, Karsten, Pohl, Martin, Gross, Oliver, Krügel, Jenny, Stock, Johanna, Patzer, Ludwig, Oh, Jun, Bernhardt, Wanja, Doyon, Anke, Vinke, Tobias, Sander, Anja, Henn, Michael, Derichs, Ute, Beetz, Rolf, Jeck, Nikola, Lange-Sperandio, Bärbel, Ponsel, Sabine, Kusser, Franziska, Uetz, Barbara, Benz, Marcus, Schmidt, Silke, Huppertz-Kessler, Christina, Kranz, Birgitta, Titieni, Andrea, Wurm, Donald, Leichter, Heinz E., Bald, Martin, Billing, Heiko, Nabhan, Marwa M., Lara, Luis Enrique, Papachristou, Fotios, Emma, Francesco, Cerkauskiene, Rimante, Azukaitis, Karolis, Wasilewska, Anna, Balasz-Chmielewska, Irena, Miklaszewska, Monika, Tkaczyk, Marcin, Sikora, Przemyslaw, Zaniew, Marcin, Niemirska, Ania, Antoniewicz, Jolanta, Lesiak, Justyna, Afonso, Alberto Caldas, Teixeira, Ana, Milosevski-Lomic, Gordana, Paripović, Dusan, Peco-Antic, Amira, Papizh, Svetlana, Bayazit, Aysun Karabay, Anarat, Ali, Soylu, Alper, Kavukcu, Salih, Candan, Cengiz, Caliskan, Salim, Canpolat, Nur, Emre, Sevinc, Alpay, Harika, Akinci, Nurver, Conkar, Secil, Poyrazoglu, Hakan M., Dusunsel, Ruhan, Burgmaier, Kathrin, Kunzmann, Kevin, Ariceta, Gema, Bergmann, Carsten, Buescher, Anja Katrin, Burgmaier, Mathias, Dursun, Ismail, Duzova, Ali, Eid, Loai, Erger, Florian, Feldkoetter, Markus, Galiano, Matthias, Geßner, Michaela, Goebel, Heike, Gokce, Ibrahim, Haffner, Dieter, Hooman, Nakysa, Hoppe, Bernd, Jankauskiene, Augustina, Klaus, Guenter, König, Jens, Litwin, Mieczyslaw, Massella, Laura, Mekahli, Djalila, Melek, Engin, Mir, Sevgi, Pape, Lars, Prikhodina, Larisa, Ranchin, Bruno, Schild, Raphael, Seeman, Tomas, Sever, Lale, Shroff, Rukshana, Soliman, Neveen A., Stabouli, Stella, Stanczyk, Malgorzata, Tabel, Yilmaz, Taranta-Janusz, Katarzyna, Testa, Sara, Thumfart, Julia, Topaloglu, Rezan, Weber, Lutz Thorsten, Wicher, Dorota, Wühl, Elke, Wygoda, Simone, Yilmaz, Alev, Zachwieja, Katarzyna, Zagozdzon, Ilona, Zerres, Klaus, Dötsch, Jörg, Schaefer, Franz, and Liebau, Max Christoph
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- 2018
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14. Indoxyl sulfate associates with cardiovascular phenotype in children with chronic kidney disease
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Holle, Johannes, Querfeld, Uwe, Kirchner, Marietta, Anninos, Alexandros, Okun, Jürgen, Thurn-Valsassina, Daniela, Bayazit, Aysun, Niemirska, Ana, Canpolat, Nur, Bulut, Ipek Kaplan, Duzova, Ali, Anarat, Ali, Shroff, Rukshana, Bilginer, Yelda, Caliskan, Salim, Candan, Cengiz, Harambat, Jerome, Özcakar, Zeynep Birsin, Soylemezoglu, Oguz, Tschumi, Sibylle, Habbig, Sandra, Yilmaz, Ebru, Balat, Ayse, Zurowska, Aleksandra, Cakar, Nilgun, Kranz, Birgitta, Ertan, Pelin, Melk, Anette, Azukaitis, Karolis, and Schaefer, Franz
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- 2019
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15. Metabolic acidosis is common and associates with disease progression in children with chronic kidney disease
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Harambat, Jérôme, Kunzmann, Kevin, Azukaitis, Karolis, Bayazit, Aysun K., Canpolat, Nur, Doyon, Anke, Duzova, Ali, Niemirska, Anna, Sözeri, Betul, Thurn-Valsassina, Daniela, Anarat, Ali, Bessenay, Lucie, Candan, Cengiz, Peco-Antic, Amira, Yilmaz, Alev, Tschumi, Sibylle, Testa, Sara, Jankauskiene, Augustina, Erdogan, Hakan, Rosales, Alejandra, Alpay, Harika, Lugani, Francesca, Arbeiter, Klaus, Mencarelli, Francesca, Kiyak, Aysel, Dönmez, Osman, Drozdz, Dorota, Melk, Anette, Querfeld, Uwe, and Schaefer, Franz
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- 2017
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16. Outbreak of Shiga toxin-producing Escherichia-coli-associated hemolytic uremic syndrome in Istanbul in 2015: outcome and experience with eculizumab
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Ağbaş, Ayşe, Göknar, Nilüfer, Akıncı, Nurver, Yıldırım, Zeynep Yürük, Taşdemir, Mehmet, Benzer, Meryem, Gökçe, İbrahim, Candan, Cengiz, Küçük, Nuran, Uzuner, Selçuk, Özçelik, Gül, Demirkol, Demet, Sever, Lale, and Çalışkan, Salim
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- 2018
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17. Effect of Implicit Argumentation Education on PSTs' Understandings about NOS
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Candan Cengiz and Filiz Kabapınar
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Argumentation ,nature of science ,pre-service science teacher education ,Chemistry ,QD1-999 - Abstract
The aim of education programs in the recent years is to develop the understandings of prospective science teachers (PSTs) who may have some inadequate and naive views on comprehension and dimensions of nature of science (NOS). There have been a number of attempt to teach NOS as explicit and implicit. However, limited number of studies have been carried out in order to find out the effect of teaching based on implicit argumentation over PSTs’ understanding of NOS. This research gap motivated the present study. Action research was benefitted in the research. VNOS-C consisting of open-ended questions was used as data collection tool. Additionally interviews were carried out with PSTs (n=16). Content analysis with qualitative and interpretive approach was carried out for the qualitative data. Findings of the study indicated that teaching via implicit argumentation has a positive effect on PSTs’ understandings about NOS even though teaching the NOS elements was not the main purpose of the intervention.
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- 2017
18. Follow-up results of patients with ADCK4 mutations and the efficacy of CoQ10 treatment
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Atmaca, Mustafa, Gulhan, Bora, Korkmaz, Emine, Inozu, Mihriban, Soylemezoglu, Oguz, Candan, Cengiz, and Bayazit, Aysun Karabay
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Coenzyme Q10 -- Physiological aspects -- Research ,Gene mutation -- Physiological aspects -- Research ,Glomerulonephritis -- Risk factors -- Genetic aspects -- Diagnosis -- Research ,Health - Abstract
Background ADCK4-related glomerulopathy is an important differential diagnosis in adolescents with steroid-resistant nephrotic syndrome (SRNS) and/or chronic kidney disease (CKD) of unknown origin. We screened adolescent patients to determine the frequency of ADCK4 mutation and the efficacy of early CoQ10 administration. Methods A total of 146 index patients aged 10-18 years, with newly diagnosed non-nephrotic proteinuria, nephrotic syndrome, or chronic renal failure and end-stage kidney disease (ESKD) of unknown etiology were screened for ADCK4 mutation. Results Twenty-eight individuals with bi-allelic mutation from 11 families were identified. Median age at diagnosis was 12.4 (interquartile range [IQR] 8.04-19.7) years. Upon first admission, all patients had albuminuria and 18 had CKD (6 ESKD). Eight were diagnosed either through the screening of family members following index case identification or during genetic investigation of proteinuria in an individual with a history of a transplanted sibling. Median age of these 8 patients was 21.5 (range 4.4-39) years. CoQ10 supplementation was administered following genetic diagnosis. Median estimated glomerular filtration rate (eGFR) just before CoQ10 administration was 140 (IQR 117-155) ml/min/1.73m.sup.2, proteinuria was 1,008 (IQR 281-1,567) mg/m.sup.2/day. After a median follow-up of 11.5 (range 4-21) months following CoQ10 administration, proteinuria was significantly decreased (median 363 [IQR 175-561] mg/m.sup.2/day, P=0.025), whereas eGFR was preserved (median 137 [IQR 113-158] ml/min/1.73m.sup.2, P=0.61). Conclusions ADCK4 mutations are one of the most common causes of adolescent-onset albuminuria and/or CKD of unknown etiology in Turkey. CoQ10 supplementation appears efficacious at reducing proteinuria, and may thereby be renoprotective., Author(s): Mustafa Atmaca [sup.1] , Bora Gulhan [sup.2] , Emine Korkmaz [sup.3] , Mihriban Inozu [sup.2] , Oguz Soylemezoglu [sup.4] , Cengiz Candan [sup.5] , Aysun Karabay Bayazit [sup.6] , [...]
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- 2017
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19. Meningococcemia in a vaccinated child receiving eculizumab and review of the literature
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Üçkardeş, Diana, primary, Göknar, Nilüfer, additional, Kasap, Nurhan, additional, Keleşoğlu, Emre, additional, Arga, Mustafa, additional, and Candan, Cengiz, additional
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- 2023
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20. Modelling of color perception of different eye colors using artificial neural networks.
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Candan Cengiz and Erdogan Köse
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- 2013
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21. Long-Term Outcome of Steroid-Resistant Nephrotic Syndrome in Children
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Trautmann, Agnes, Schnaidt, Sven, Lipska-Ziętkiewicz, Beata S., Bodria, Monica, Ozaltin, Fatih, Emma, Francesco, Anarat, Ali, Melk, Anette, Azocar, Marta, Oh, Jun, Saeed, Bassam, Gheisari, Alaleh, Caliskan, Salim, Gellermann, Jutta, Higuita, Lina Maria Serna, Jankauskiene, Augustina, Drozdz, Dorota, Mir, Sevgi, Balat, Ayse, Szczepanska, Maria, Paripovic, Dusan, Zurowska, Alexandra, Bogdanovic, Radovan, Yilmaz, Alev, Ranchin, Bruno, Baskin, Esra, Erdogan, Ozlem, Remuzzi, Giuseppe, Firszt-Adamczyk, Agnieszka, Kuzma-Mroczkowska, Elzbieta, Litwin, Mieczyslaw, Murer, Luisa, Tkaczyk, Marcin, Jardim, Helena, Wasilewska, Anna, Printza, Nikoleta, Fidan, Kibriya, Simkova, Eva, Borzecka, Halina, Staude, Hagen, Hees, Katharina, Schaefer, Franz, Azocar, M, Quiroz, Lily, Higuita, LM Serna, Dušek, Jiří, Ranchin, B, Fischbach, Michel, Davitaia, Tinatin, Gellerman, J, Oh, J, Melk, A, Schaefer, F, Wigger, Marianne, Printza, N, Sallay, Peter, Gheissari, Alaleh, Noris, Marina, Pasini, Andrea, Ghiggeri, Gian Marco, Ardissino, Gianluigi, Benetti, Elisa, Emma, F, Aoun, Bilal, Abou-Jaoudé, Pauline, Jankauskiene, A, Wasilewska, A, Gacka, Ewa, Zurowska, A, Drozdz, D, Tkaczyk, M, Lodz, Małgorzata Stańczyk, Borzecka, H, Silska, Magdalena, Jarmolinski, Tomasz, Firszt-Adamczyk, A, Ksiazek, Joanna, Kuzma-Mroczkowska, E, Medynska, Anna, Szczepanska, M, Afonso, Alberto Caldas, Jardim, H, Belgrade, Amira Peco-Antic, Bogdanovic, R, Krmar, Rafael T, Simonetti, Giacomo D, Saeed, B, Anarat, A, Balat, A, Baskin, E, Cakar, Nilgun, Erdogan, O, Özcakar, Birsin, Ozaltin, F, Sakallioglu, Onur, Soylemezoglu, Oguz, Akman, Sema, Gok, Faysal, Caliskan, S, Candan, Cengiz, Yilmaz, A, Mir, S, Akil, Ipek, Ertan, Pelin, Özkaya, Ozan, Kalyoncu, Mukaddes, Simkova, E, Alhammadi, Entesar, and Sobko, Roman
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- 2017
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22. Long-term Results in Children with Henoch-Schönlein Nephritis
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ASLAN, Caner, primary, GOKNAR, Nilufer, additional, KELESOGLU, Emre, additional, UCKARDES, Diana, additional, and CANDAN, Cengiz, additional
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- 2022
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23. Early childhood height-adjusted total kidney volume as a risk marker of kidney survival in ARPKD
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Nalcacioglu, Hulya, Dunand, Oliver, Mastrangelo, Antonio, Murer, Luisa, Emma, Francesco, Ruzgiene, Dovile, Taranta-Janusz, Katarzyna, Balasz-Chmielewska, Irena, Miklaszewska, Monika, Stanczyk, Malgorzata, Sikora, Przemyslaw, Kowalewska, Claudia, Szczepanska, Maria, Teixeira, Ana, Rachisan, Andreea, Papachristou, Fotios, Paripović, Dušan, Prikhodina, Larisa, Jilani, Houweyda, Bayazit, Aysun Karabay, Soylu, Alper, Candan, Cengiz, Sever, Lale, Emre, Sevinc, Cicek, Neslihan, Akinci, Nurver, Mir, Sevgi, Poyrazoğlu, Hakan M., Tabel, Yilmaz, Mencarelli, Francesca, Burgmaier, Kathrin, Kilian, Samuel, Arbeiter, Klaus, Atmis, Bahriye, Büscher, Anja, Derichs, Ute, Dursun, Ismail, Duzova, Ali, Eid, Loai Akram, Galiano, Matthias, Gessner, Michaela, Gokce, Ibrahim, Haeffner, Karsten, Hooman, Nakysa, Jankauskiene, Augustina, Körber, Friederike, Longo, Germana, Massella, Laura, Mekahli, Djalila, Miloševski-Lomić, Gordana, Rus, Rina, Shroff, Rukshana, Stabouli, Stella, Weber, Lutz T., Wygoda, Simone, Yilmaz, Alev, Zachwieja, Katarzyna, Zagozdzon, Ilona, Dötsch, Jörg, Schaefer, Franz, Liebau, Max Christoph, Potemkina, Alexandra, Ranguelov, Nadejda, Collard, Laure, De Mul, Aurélie, Feldkoetter, Markus, Seeman, Tomas, Zieg, Jakub, Thumfart, Julia, Grundmann, Franziska, Buchholz, Björn, Pape, Lars, Gross, Oliver, Patzer, Ludwig, Schild, Raphael, Haffner, Dieter, Bernhardt, Wanja, Wuehl, Elke, Henn, Michael, Halbritter, Jan, Klaus, Günter, Lechner, Felix, Lange-Sperandio, Bärbel, Uetz, Barbara, Benz, Marcus, König, Jens, Staude, Hagen, Wurm, Donald, Bald, Martin, Soliman, Neveen A., Ariceta, Gema, Rodriguez, Juan David Gonzalez, de la Cerda Ojeda, Francisco, Harambat, Jerome, Ranchin, Bruno, Fila, Marc, Dossier, Claire, Boyer, Olivia, Marlais, Matko, UCL - (SLuc) Département de pédiatrie, Ruzgienė, Dovilė, Burgmaier, Kathrin, Kilian, Samuel, Arbeiter, Klaus, Atmis, Bahriye, Buescher, Anja, Derichs, Ute, Dursun, Ismail, Duzova, Ali, Eid, Loai Akram, Galiano, Matthias, Gessner, Michaela, Gokce, Ibrahim, Haeffner, Karsten, Hooman, Nakysa, Jankauskiene, Augustina, Koerber, Friederike, Longo, Germana, Massella, Laura, Mekahli, Djalila, Milosevski-Lomic, Gordana, Nalcacioglu, Hulya, Rus, Rina, Shroff, Rukshana, Stabouli, Stella, Weber, Lutz T., Wygoda, Simone, Yilmaz, Alev, Zachwieja, Katarzyna, Zagozdzon, Ilona, Doetsch, Joerg, Schaefer, Franz, and Liebau, Max Christoph
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Liver Cirrhosis ,Male ,glomerulus filtration rate ,Medizin ,cell surface receptor ,preschool child ,DISEASE ,Cohort Studies ,Chronic kidney disease ,Polycystic kidney disease ,Medicine ,genetics ,Longitudinal Studies ,Child ,pathophysiology ,Ultrasonography ,Kidney ,Multidisciplinary ,longitudinal study ,organ size ,chronic kidney failure ,biological marker ,cohort analysis ,Prognosis ,Autosomal Recessive Polycystic Kidney Disease ,PKHD1 protein, human ,Multidisciplinary Sciences ,medicine.anatomical_structure ,female ,Quartile ,Child, Preschool ,Cohort ,Disease Progression ,Science & Technology - Other Topics ,Glomerular Filtration Rate ,medicine.medical_specialty ,kidney ,Adolescent ,Science ,Urology ,Renal function ,Kidney Volume ,Receptors, Cell Surface ,Article ,Humans ,ddc:610 ,human ,Renal Insufficiency, Chronic ,Polycystic Kidney, Autosomal Recessive ,Paediatric kidney disease ,Science & Technology ,business.industry ,echography ,Infant ,medicine.disease ,mortality ,kidney polycystic disease ,disease exacerbation ,physiology ,business ,metabolism ,Biomarkers ,Kidney disease - Abstract
Autosomal recessive polycystic kidney disease (ARPKD) is characterized by bilateral fibrocystic changes resulting in pronounced kidney enlargement. Impairment of kidney function is highly variable and widely available prognostic markers are urgently needed as a base for clinical decision-making and future clinical trials. In this observational study we analyzed the longitudinal development of sonographic kidney measurements in a cohort of 456 ARPKD patients from the international registry study ARegPKD. We furthermore evaluated correlations of sonomorphometric findings and functional kidney disease with the aim to describe the natural disease course and to identify potential prognostic markers. Kidney pole-to-pole (PTP) length and estimated total kidney volume (eTKV) increase with growth throughout childhood and adolescence despite individual variability. Height-adjusted PTP length decreases over time, but such a trend cannot be seen for height-adjusted eTKV (haeTKV) where we even observed a slight mean linear increase of 4.5 ml/m per year during childhood and adolescence for the overall cohort. Patients with two null PKHD1 variants had larger first documented haeTKV values than children with missense variants (median (IQR) haeTKV 793 (450–1098) ml/m in Null/null, 403 (260–538) ml/m in Null/mis, 230 (169–357) ml/m in Mis/mis). In the overall cohort, estimated glomerular filtration rate decreases with increasing haeTKV (median (IQR) haeTKV 210 (150–267) ml/m in CKD stage 1, 472 (266–880) ml/m in stage 5 without kidney replacement therapy). Strikingly, there is a clear correlation between haeTKV in the first eighteen months of life and kidney survival in childhood and adolescence with ten-year kidney survival rates ranging from 20% in patients of the highest to 94% in the lowest quartile. Early childhood haeTKV may become an easily obtainable prognostic marker of kidney disease in ARPKD, e.g. for the identification of patients for clinical studies. © 2021, The Author(s)., ESPN 2014.2; PKD Foundation, PKDF; Bundesministerium für Bildung und Forschung, BMBF: 01GM1515, 01GM1903; Universität zu Köln, UoC; Marga und Walter Boll-Stiftung; Universitätsklinikum Köln, We thank the German Society for Pediatric Nephrology (GPN), the ESCAPE Network, and the European Society for Paediatric Nephrology (ESPN; Working Groups CAKUT and Inherited Renal Diseases) for their support. ML was supported by grants of the GPN, ESPN (Grant ESPN 2014.2), and the German PKD foundation. KB and ML were supported by the Medical Faculty of the University of Cologne (Koeln Fortune program), and the Marga and Walter Boll-Foundation. FS and ML are supported by the German Federal Ministry of Research and Education (BMBF grant 01GM1515 and 01GM1903). This work was generated within the European Reference Network for Rare Kidney Disorders (ERKNet).
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- 2021
24. Bilateral Native Kidney Papillary Renal Cell Carcinomas in a 11-Year-Old Renal Transplant Patient
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Durakbaşa, Çiğdem Ulukaya, additional, Ugurlu, Deniz, additional, Bozbeyoglu, Sabriye Gulcin, additional, Aydoner, Sinem, additional, Seneldir, Hatice, additional, Candir, Mehmet Onur, additional, Candan, Cengiz, additional, and Gemici, Atilla, additional
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- 2022
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25. Hepatocyte Nuclear Factor 1 Beta Mutation-associated Newborn Onset of Glomerulocystic Kidney Disease: A Case Presentation
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Göknar, Nilüfer, primary, Ekici Avcı, Melda, additional, Üçkardeş, Diana, additional, Keleşoğlu, Emre, additional, Tekkuş Ermiş, Kübra, additional, and Candan, Cengiz, additional
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- 2021
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26. Subclinical cardiovascular disease and its association with risk factors in children with steroid-resistant nephrotic syndrome
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Candan, Cengiz, Canpolat, Nur, Gokalp, Selman, Yildiz, Nurdan, Turhan, Pinar, Tasdemir, Mehmet, Sever, Lale, and Caliskan, Salim
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Children -- Diseases ,Steroids (Drugs) -- Usage -- Health aspects ,Nephrotic syndrome -- Drug therapy -- Patient outcomes ,Cardiovascular diseases -- Risk factors ,Health - Abstract
Background The aim of this study was to evaluate the presence of subclinical cardiovascular disease (CVD) and its relation to risk factors in pediatric patients with steroid-resistant nephrotic syndrome (NS). Methods Thirty-seven patients with normal renal function were compared with 22 healthy controls regarding the presence of subclinical CVD. Measurements included aortic pulse wave velocity (PWV), carotid intima media thickness (IMT), and left ventricular mass (LVM). Patients were additionally assessed for blood pressure (BP) pattern and the presence of hypertension by 24-h ambulatory blood pressure monitoring. Results Compared with the controls, patients had significantly higher mean aortic PWV-standard deviation scores (SDS), mean carotid IMT-SDS, and LVM index (p Conclusions Based on these results, steroid-resistant NS children generally are at high risk of cardiovascular complications, but the increased risk is likely to be multifactorial. Keywords Steroid-resistant nephrotic syndrome Aortic Stiffness * Atherosclerosis * Cardiovascular disease * Childhood, Introduction Idiopathic nephrotic syndrome (NS) in the adult population is considered to be an important risk factor for accelerated atherosclerosis [1]. However the role of idiopathic NS in the development [...]
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- 2014
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27. Refining genotype–phenotype correlations in 304 patients with autosomal recessive polycystic kidney disease and PKHD1 gene variants
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Burgmaier, Kathrin, primary, Brinker, Leonie, additional, Erger, Florian, additional, Beck, Bodo B., additional, Benz, Marcus R., additional, Bergmann, Carsten, additional, Boyer, Olivia, additional, Collard, Laure, additional, Dafinger, Claudia, additional, Fila, Marc, additional, Kowalewska, Claudia, additional, Lange-Sperandio, Bärbel, additional, Massella, Laura, additional, Mastrangelo, Antonio, additional, Mekahli, Djalila, additional, Miklaszewska, Monika, additional, Ortiz-Bruechle, Nadina, additional, Patzer, Ludwig, additional, Prikhodina, Larisa, additional, Ranchin, Bruno, additional, Ranguelov, Nadejda, additional, Schild, Raphael, additional, Seeman, Tomas, additional, Sever, Lale, additional, Sikora, Przemyslaw, additional, Szczepanska, Maria, additional, Teixeira, Ana, additional, Thumfart, Julia, additional, Uetz, Barbara, additional, Weber, Lutz Thorsten, additional, Wühl, Elke, additional, Zerres, Klaus, additional, Dötsch, Jörg, additional, Schaefer, Franz, additional, Liebau, Max Christoph, additional, Eid, Loai Akram, additional, Arbeiter, Klaus, additional, Godefroid, Nathalie, additional, Lombet, Jacques, additional, De Mul, Aurélie, additional, Feldkoetter, Markus, additional, Zieg, Jakub, additional, Grundmann, Franziska, additional, Galiano, Matthias, additional, Buchholz, Björn, additional, Buescher, Anja, additional, Häffner, Karsten, additional, Gross, Oliver, additional, Oh, Jun, additional, Haffner, Dieter, additional, Bernhardt, Wanja, additional, Schaefer, Susanne, additional, Wygoda, Simone, additional, Halbritter, Jan, additional, Derichs, Ute, additional, Klaus, Günter, additional, Lechner, Felix, additional, Ponsel, Sabine, additional, König, Jens, additional, Staude, Hagen, additional, Wurm, Donald, additional, Bald, Martin, additional, Gessner, Michaela, additional, Soliman, Neveen A., additional, Ariceta, Gema, additional, Gonzalez Rodriguez, Juan David, additional, Ojeda, Francisco de la Cerda, additional, Harambat, Jerome, additional, Morin, Denis, additional, Dossier, Claire, additional, Dorval, Guillaume, additional, Shroff, Rukshana, additional, Stabouli, Stella, additional, Hooman, Nakysa, additional, Mencarelli, Francesca, additional, Morello, William, additional, Longo, Germana, additional, Emma, Francesco, additional, Jankauskiene, Augustina, additional, Taranta-Janusz, Katarzyna, additional, Zagozdzon, Ilona, additional, Zachwieja, Katarzyna, additional, Stanczyk, Malgorzata, additional, Bienias, Beata, additional, Litwin, Mieczyslaw, additional, Morawiec-Knysak, Aurelia, additional, Afonso, Alberto Caldas, additional, Dunand, Oliver, additional, Rachisan, Andreea, additional, Miloševski-Lomić, Gordana, additional, Papizh, Svetlana, additional, Rus, Rina, additional, Jilani, Houweyda, additional, Atmis, Bahriye, additional, Duzova, Ali, additional, Soylu, Alper, additional, Candan, Cengiz, additional, Caliskan, Salim, additional, Yilmaz, Alev, additional, Gökce, İbrahim, additional, Akinci, Nurver, additional, Mir, Sevgi, additional, Dursun, Ismail, additional, Tabel, Yilmaz, additional, and Nalcacioglu, Hulya, additional
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- 2021
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28. Rituximab treatment for difficult-to-treat nephrotic syndrome in children: a multicenter, retrospective study
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TAŞDEMİR, Mehmet, primary, CANPOLAT, Nur, additional, YILDIZ, Nurdan, additional, ÖZÇELİK, Gül, additional, BENZER, Meryem, additional, SAYGILI, Seha Kamil, additional, ÖZKAYIN, Emine Neşe, additional, TÜRKKAN, Özde Nisa, additional, BALAT, Ayşe, additional, CANDAN, Cengiz, additional, ÇELAKIL, Mehtap, additional, YAVUZ, Sevgi, additional, AKINCI, Nurver, additional, GÖKNAR, Nilüfer, additional, AKGÜN, Cihangir, additional, TÜLPAR, Sebahat, additional, ALPAY, Harika, additional, SEVER, Fatma Lale, additional, and BİLGE, İlmay, additional
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- 2021
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29. Henoch Schönlein Purpura / Ig A Vasculitis in Children and Risk Factors for Renal Involvement
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Demir, Selcan, primary, Candan, Cengiz, primary, Turhan, Pınar, primary, and Ergüven, Müferet, primary
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- 2021
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30. Glucose intolerance: is it a risk factor for cardiovascular disease in children with chronic kidney disease?
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Canpolat, Nur, Caliskan, Salim, Sever, Lale, Guzeltas, Alper, Kantarci, Fatih, Candan, Cengiz, Civilibal, Mahmut, Kasapcopur, Ozgur, and Arisoy, Nil
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- 2012
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31. Dialysate CA125 levels after 5 years on continuous peritoneal dialysis
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Candan, Cengiz, Turhan, Pınar, Sever, Lale, Civilibal, Mahmut, Canpolat, Nur, Caliskan, Salim, Kasapcopur, Ozgur, and Arisoy, Nil
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- 2011
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32. Left ventricular systolic and diastolic function and carotid intima-media thickness in pediatric dialysis patients
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Civilibal, Mahmut, Oflaz, Huseyin, Caliskan, Salim, Candan, Cengiz, Canpolat, Nur, Pehlivan, Gulseren, Sever, Lale, Kasapcopur, Ozgur, and Arisoy, Nil
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- 2009
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33. Blood volume monitoring to adjust dry weight in hypertensive pediatric hemodialysis patients
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Candan, Cengiz, Sever, Lale, Civilibal, Mahmut, Caliskan, Salim, and Arisoy, Nil
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- 2009
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34. Progression of coronary calcification in pediatric chronic kidney disease stage 5
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Civilibal, Mahmut, Caliskan, Salim, Kurugoglu, Sebuh, Candan, Cengiz, Canpolat, Nur, Sever, Lale, Kasapcopur, Ozgur, and Arisoy, Nil
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- 2009
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35. Traditional and “new” cardiovascular risk markers and factors in pediatric dialysis patients
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Civilibal, Mahmut, Caliskan, Salim, Oflaz, Huseyin, Sever, Lale, Candan, Cengiz, Canpolat, Nur, Kasapcopur, Ozgur, Bugra, Zehra, and Arisoy, Nil
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- 2007
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36. Severe neurological outcomes after very early bilateral nephrectomies in patients with autosomal recessive polycystic kidney disease (ARPKD)
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Häffner, Karsten, Gross, Oliver, Bernhardt, Wanja, Doyon, Anke, Henn, Michael, Halbritter, Jan, Derichs, Ute, Klaus, Günter, Lange-Sperandio, Bärbel, Uetz, Barbara, Benz, Marcus, Titieni, Andrea, Staude, Hagen, Leichter, Heinz E., Soliman, Neveen A., Lara, Luis Enrique, de la Cerda Ojeda, Francisco, Harambat, Jerome, Ranchin, Bruno, Fila, Marc, Dossier, Claire, Boyer, Olivia, Stabouli, Stella, Hooman, Nakysa, Mencarelli, Francesca, Morello, William, Longo, Germana, Emma, Francesco, Ruzgiene, Dovile, Wasilewska, Anna, Balasz-Chmielewska, Irena, Miklaszewska, Monika, Stanczyk, Malgorzata, Sikora, Przemyslaw, Litwin, Mieczyslaw, Morawiec-Knysak, Aurelia, Teixeira, Ana, Milosevski-Lomic, Gordana, Prikhodina, Larisa, Rus, Rina, Jilani, Houweyda, Melek, Engin, Duzova, Ali, Candan, Cengiz, Sever, Lale, Ranguelov, Nadejda, Yilmaz, Alev, Cicek, Neslihan, Akinci, Nurver, Mir, Sevgi, Dursun, Ismail, Tabel, Yilmaz, Nalcacioglu, Hulya, Shroff, Rukshana, Marlais, Matko, Soylu, Alper, Arbeiter, Klaus, Eid, Loai Akram, Liebau, Max Christoph, Schaefer, Franz, Oh, Jun, Dötsch, Jörg, Zagozdzon, Ilona, Wygoda, Simone, Wurm, Donald, Wühl, Elke, Weber, Lutz Thorsten, Tkaczyk, Marcin, Burgmaier, Kathrin, Ariceta, Gema, Bald, Martin, Buescher, Anja Katrin, Burgmaier, Mathias, Erger, Florian, Gessner, Michaela, GÖKCE, İBRAHİM, König, Jens, Kowalewska, Claudia, Massella, Laura, Mastrangelo, Antonio, Mekahli, Djalila, Pape, Lars, Patzer, Ludwig, Potemkina, Alexandra, Schalk, Gesa, Schild, Raphael, Szczepanska, Maria, Taranta-Janusz, Katarzyna, Collard, Laure, De Mul, Aurélie, Feldkoetter, Markus, Seeman, Tomas, Thumfart, Julia, Grundmann, Franziska, Galiano, Matthias, Buchholz, Björn, Buescher, Rainer, UCL - (SLuc) Service de pédiatrie générale, De Mul, Aurélie, Burgmaier, Kathrin, Ariceta, Gema, Bald, Martin, Buescher, Anja Katrin, Burgmaier, Mathias, Erger, Florian, Gessner, Michaela, Gokce, Ibrahim, Koenig, Jens, Kowalewska, Claudia, Massella, Laura, Mastrangelo, Antonio, Mekahli, Djalila, Pape, Lars, Patzer, Ludwig, Potemkina, Alexandra, Schalk, Gesa, Schild, Raphael, Shroff, Rukshana, Szczepanska, Maria, Taranta-Janusz, Katarzyna, Tkaczyk, Marcin, Weber, Lutz Thorsten, Wuehl, Elke, Wurm, Donald, Wygoda, Simone, Zagozdzon, Ilona, Doetsch, Joerg, Oh, Jun, Schaefer, Franz, Liebau, Max Christoph, and Ege Üniversitesi
- Subjects
Male ,Pediatrics ,medicine.medical_treatment ,Medizin ,030232 urology & nephrology ,INFANTS ,lcsh:Medicine ,Nephrectomy ,RECOMMENDATIONS ,Cohort Studies ,0302 clinical medicine ,Postoperative Complications ,Risk Factors ,HYPOTENSION ,Polycystic Kidney ,Medicine ,UNILATERAL NEPHRECTOMY ,ENCODES ,lcsh:Science ,Renal Dialysis/statistics & numerical data ,PERITONEAL-DIALYSIS ,Kidney ,ddc:618 ,Multidisciplinary ,Autosomal recessive polycystic kidney disease (ARPKD) ,Autosomal Recessive Polycystic Kidney Disease ,medicine.anatomical_structure ,Cohort ,ARegPKD consortium ,Disease Progression ,Female ,Cohort study ,Nephrectomy/adverse effects ,medicine.medical_specialty ,Renal function ,MATURATION ,Article ,03 medical and health sciences ,Polycystic kidney disease ,Renal Dialysis ,030225 pediatrics ,MANAGEMENT ,Humans ,In patient ,Dialysis ,Polycystic Kidney, Autosomal Recessive ,Nervous System Diseases/epidemiology/etiology ,Autosomal Recessive/surgery ,Paediatric kidney disease ,business.industry ,lcsh:R ,1ST YEAR ,NEUROPATHY ,Infant, Newborn ,Infant ,Newborn ,medicine.disease ,Postoperative Complications/epidemiology/etiology ,lcsh:Q ,Nervous System Diseases ,business - Abstract
To test the association between bilateral nephrectomies in patients with autosomal recessive polycystic kidney disease (ARPKD) and long-term clinical outcome and to identify risk factors for severe outcomes, a dataset comprising 504 patients from the international registry study ARegPKD was analyzed for characteristics and complications of patients with very early (? 3 months; VEBNE) and early (4–15 months; EBNE) bilateral nephrectomies. Patients with very early dialysis (VED, onset ? 3 months) without bilateral nephrectomies and patients with total kidney volumes (TKV) comparable to VEBNE infants served as additional control groups. We identified 19 children with VEBNE, 9 with EBNE, 12 with VED and 11 in the TKV control group. VEBNE patients suffered more frequently from severe neurological complications in comparison to all control patients. Very early bilateral nephrectomies and documentation of severe hypotensive episodes were independent risk factors for severe neurological complications. Bilateral nephrectomies within the first 3 months of life are associated with a risk of severe neurological complications later in life. Our data support a very cautious indication of very early bilateral nephrectomies in ARPKD, especially in patients with residual kidney function, and emphasize the importance of avoiding severe hypotensive episodes in this at-risk cohort. © 2020, The Author(s)., Marga und Walter Boll-Stiftung Universität zu Köln, UoC Bundesministerium für Bildung und Forschung, BMBF: 01GM1903, 01GM1515 PKD Foundation, PKDF European Paediatric Neurology Society, EPNS, We thank the German Society for Pediatric Nephrology (GPN) and the ESCAPE Network for their support. ML was supported by grants of the GPN, the European Society for Paediatric Nephrology (ESPN), the German PKD foundation, the Koeln Fortune program, the GEROK program of the Medical Faculty of University of Cologne, and the Marga and Walter Boll-Foundation. FS and ML are supported by the the German Federal Ministry of Research and Education (BMBF grant 01GM1515 and 01GM1903). KB was supported by the Koeln Fortune program of the Medical Faculty of University of Cologne and the Marga and Walter Boll-Foundation. This work was generated within the European Reference Network for Rare Kidney Disorders (ERKNet). Open Access funding provided by Projekt DEAL.
- Published
- 2020
37. CLINICAL CHARACTERISTICS OF PATIENTS WITH GENETICALLY CONFIRMED ALPORT SYNDROME
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HAYRAN, KADİR MUTLU, SOYLU, ALPER, TOPALOĞLU, REZAN, Ozdemir, Gulsah, GÜLHAN, BORA, Atayar, Emine, CANPOLAT, Nur, Soylemezoglu, Oguz, ÖZÇAKAR, ZEYNEP BİRSİN, Eroglu, Fehime Kara, CANDAN, CENGİZ, Demir, Belde Kasap, YÜKSEL, SELÇUK, ALPAY, HARİKA, Agbas, Ayse, DÜZOVA, ALİ, and ÖZALTIN, FATİH
- Published
- 2020
38. Early childhood height-adjusted total kidney volume as a risk marker of kidney survival in ARPKD
- Author
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UCL - (SLuc) Département de pédiatrie, Nalcacioglu, Hulya, Dunand, Oliver, Mastrangelo, Antonio, Murer, Luisa, Emma, Francesco, Ruzgiene, Dovile, Taranta-Janusz, Katarzyna, Balasz-Chmielewska, Irena, Miklaszewska, Monika, Stanczyk, Malgorzata, Sikora, Przemyslaw, Kowalewska, Claudia, Szczepanska, Maria, Teixeira, Ana, Rachisan, Andreea, Papachristou, Fotios, Paripović, Dušan, Prikhodina, Larisa, Jilani, Houweyda, Bayazit, Aysun Karabay, Soylu, Alper, Candan, Cengiz, Sever, Lale, Emre, Sevinc, Cicek, Neslihan, Akinci, Nurver, Mir, Sevgi, Poyrazoğlu, Hakan M., Tabel, Yilmaz, Mencarelli, Francesca, Burgmaier, Kathrin, Kilian, Samuel, Arbeiter, Klaus, Atmis, Bahriye, Büscher, Anja, Derichs, Ute, Dursun, Ismail, Duzova, Ali, Eid, Loai Akram, Galiano, Matthias, Gessner, Michaela, Gokce, Ibrahim, Haeffner, Karsten, Hooman, Nakysa, Jankauskiene, Augustina, Körber, Friederike, Longo, Germana, Massella, Laura, Mekahli, Djalila, Miloševski-Lomić, Gordana, Rus, Rina, Shroff, Rukshana, Stabouli, Stella, Weber, Lutz T., Wygoda, Simone, Yilmaz, Alev, Zachwieja, Katarzyna, Zagozdzon, Ilona, Dötsch, Jörg, Schaefer, Franz, Liebau, Max Christoph, Potemkina, Alexandra, Ranguelov, Nadejda, Collard, Laure, De Mul, Aurélie, Feldkoetter, Markus, Seeman, Tomas, Zieg, Jakub, Thumfart, Julia, Grundmann, Franziska, Buchholz, Björn, Pape, Lars, Gross, Oliver, Patzer, Ludwig, Schild, Raphael, Haffner, Dieter, Bernhardt, Wanja, Wuehl, Elke, Henn, Michael, Halbritter, Jan, Klaus, Günter, Lechner, Felix, Lange-Sperandio, Bärbel, Uetz, Barbara, Benz, Marcus, König, Jens, Staude, Hagen, Wurm, Donald, Bald, Martin, Soliman, Neveen A., Ariceta, Gema, Rodriguez, Juan David Gonzalez, de la Cerda Ojeda, Francisco, Harambat, Jerome, Ranchin, Bruno, Fila, Marc, Dossier, Claire, Boyer, Olivia, Marlais, Matko, UCL - (SLuc) Département de pédiatrie, Nalcacioglu, Hulya, Dunand, Oliver, Mastrangelo, Antonio, Murer, Luisa, Emma, Francesco, Ruzgiene, Dovile, Taranta-Janusz, Katarzyna, Balasz-Chmielewska, Irena, Miklaszewska, Monika, Stanczyk, Malgorzata, Sikora, Przemyslaw, Kowalewska, Claudia, Szczepanska, Maria, Teixeira, Ana, Rachisan, Andreea, Papachristou, Fotios, Paripović, Dušan, Prikhodina, Larisa, Jilani, Houweyda, Bayazit, Aysun Karabay, Soylu, Alper, Candan, Cengiz, Sever, Lale, Emre, Sevinc, Cicek, Neslihan, Akinci, Nurver, Mir, Sevgi, Poyrazoğlu, Hakan M., Tabel, Yilmaz, Mencarelli, Francesca, Burgmaier, Kathrin, Kilian, Samuel, Arbeiter, Klaus, Atmis, Bahriye, Büscher, Anja, Derichs, Ute, Dursun, Ismail, Duzova, Ali, Eid, Loai Akram, Galiano, Matthias, Gessner, Michaela, Gokce, Ibrahim, Haeffner, Karsten, Hooman, Nakysa, Jankauskiene, Augustina, Körber, Friederike, Longo, Germana, Massella, Laura, Mekahli, Djalila, Miloševski-Lomić, Gordana, Rus, Rina, Shroff, Rukshana, Stabouli, Stella, Weber, Lutz T., Wygoda, Simone, Yilmaz, Alev, Zachwieja, Katarzyna, Zagozdzon, Ilona, Dötsch, Jörg, Schaefer, Franz, Liebau, Max Christoph, Potemkina, Alexandra, Ranguelov, Nadejda, Collard, Laure, De Mul, Aurélie, Feldkoetter, Markus, Seeman, Tomas, Zieg, Jakub, Thumfart, Julia, Grundmann, Franziska, Buchholz, Björn, Pape, Lars, Gross, Oliver, Patzer, Ludwig, Schild, Raphael, Haffner, Dieter, Bernhardt, Wanja, Wuehl, Elke, Henn, Michael, Halbritter, Jan, Klaus, Günter, Lechner, Felix, Lange-Sperandio, Bärbel, Uetz, Barbara, Benz, Marcus, König, Jens, Staude, Hagen, Wurm, Donald, Bald, Martin, Soliman, Neveen A., Ariceta, Gema, Rodriguez, Juan David Gonzalez, de la Cerda Ojeda, Francisco, Harambat, Jerome, Ranchin, Bruno, Fila, Marc, Dossier, Claire, Boyer, Olivia, and Marlais, Matko
- Abstract
Autosomal recessive polycystic kidney disease (ARPKD) is characterized by bilateral fibrocystic changes resulting in pronounced kidney enlargement. Impairment of kidney function is highly variable and widely available prognostic markers are urgently needed as a base for clinical decision-making and future clinical trials. In this observational study we analyzed the longitudinal development of sonographic kidney measurements in a cohort of 456 ARPKD patients from the international registry study ARegPKD. We furthermore evaluated correlations of sonomorphometric findings and functional kidney disease with the aim to describe the natural disease course and to identify potential prognostic markers. Kidney pole-to-pole (PTP) length and estimated total kidney volume (eTKV) increase with growth throughout childhood and adolescence despite individual variability. Height-adjusted PTP length decreases over time, but such a trend cannot be seen for height-adjusted eTKV (haeTKV) where we even observed a slight mean linear increase of 4.5 ml/m per year during childhood and adolescence for the overall cohort. Patients with two null PKHD1 variants had larger first documented haeTKV values than children with missense variants (median (IQR) haeTKV 793 (450–1098) ml/m in Null/null, 403 (260–538) ml/m in Null/mis, 230 (169–357) ml/m in Mis/mis). In the overall cohort, estimated glomerular filtration rate decreases with increasing haeTKV (median (IQR) haeTKV 210 (150–267) ml/m in CKD stage 1, 472 (266–880) ml/m in stage 5 without kidney replacement therapy). Strikingly, there is a clear correlation between haeTKV in the first eighteen months of life and kidney survival in childhood and adolescence with ten-year kidney survival rates ranging from 20% in patients of the highest to 94% in the lowest quartile. Early childhood haeTKV may become an easily obtainable prognostic marker of kidney disease in ARPKD, e.g. for the identification of patients for clinical studies.
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- 2021
39. Rapid Drug Desensitization to Iron Sucrose in Pediatrics.
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Karakurt, Leman Tuba, Uckardes, Diana, Cavkaytar, Özlem, Candan, Cengiz, and Arga, Mustafa
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SUCROSE ,URTICARIA ,RECOMBINANT erythropoietin ,DRUG side effects ,CHILD patients - Abstract
Oral iron therapy was ineffective in our patient, and iv iron therapy was required for an optimal erythropoietic response to rHuEPO and to rapidly restore iron.[[1], [3]] Despite the patient being hypersensitive to iron sucrose, we were able to successfully desensitize him by following the aforementioned protocol. At the end of the treatment, the serum hemoglobin and ferritin levels of the patient were above the target value (Hb: 11.4 g/dL Ferritin: 144 /L), and then, the rHuEPO treatment was initiated. However, due to the requirement of serum ferritin level >100 /L for the insurance-related approval of rHuEPO treatment in our country, iv iron treatment was obligatory for the patient. [Extracted from the article]
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- 2023
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40. Coronary artery calcifications in children with end-stage renal disease
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Civilibal, Mahmut, Caliskan, Salim, Adaletli, Ibrahim, Oflaz, Huseyin, Sever, Lale, Candan, Cengiz, Canpolat, Nur, Kasapcopur, Ozgur, Kuruoglu, Sebuh, and Arisoy, Nil
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- 2006
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41. Anocutaneous reflex revisited: how valuable is its determination in children with spina bifida? a descriptive study in a cohort of 217 patients
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Ozel, Kerem, primary, Canmemis, Arzu, additional, Goknar, Nilufer, additional, Candan, Cengiz, additional, Alizada, Orkhan, additional, and Alatas, Ibrahim, additional
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- 2021
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42. Spina bifidalı çocukların yaşam kalitesi üzerine temiz aralıklı kateterizasyonun etkisi
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ARIKAN, Abdullah, primary and CANDAN, Cengiz, additional
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- 2020
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43. P0063CLINICAL CHARACTERISTICS OF PATIENTS WITH GENETICALLY CONFIRMED ALPORT SYNDROME
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Ozdemir, Gulsah, primary, Gulhan, Bora, primary, Atayar, Emine, primary, Canpolat, Nur, primary, Soylemezoglu, Oguz, primary, Ozcakar, Z Birsin, primary, Kara Eroğlu, Fehime, primary, Candan, Cengiz, primary, Kasap Demir, Belde, primary, Soylu, Alper, primary, Yuksel, Selcuk, primary, Alpay, Harika, primary, Agbas, Ayse, primary, Duzova, Ali, primary, Hayran, Mutlu, primary, Ozaltin, Fatih, primary, and Topaloglu, Rezan, primary
- Published
- 2020
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44. Prospective teachers and secondary students' ideas on global environmental issues: Contradictions or similarities
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Filiz Kabapinar, Candan Cengiz, and Oya Ağlarcı
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Marketing ,Economics and Econometrics ,General Chemical Engineering ,General Materials Science - Abstract
The present study aims to investigate prospective teachers' (PTs') and secondary students' (SSs') ideas related to environmental issues. A case study design was adopted in this study. SSs (n = 100) who received instruction on environmental issues and PTs (n = 150) who attended courses concerning environmental education were participated in this study. An open-ended questionnaire was designed and used as a data collection tool. Written answers of the participants were analysed in ideographic terms. The results of the study showed that the PTs held a range of alternative ideas similar to SSs. They both linked environmental problems which were irrelevant with cause' effect chain. Yet, PTs provided a more scientific definitions regarding greenhouse effect, global warming and ozone layer depletion as compared to SSs. Keywords: Global environmental issues, prospective teachers, secondary students, environmental education, greenhouse effect, global warming, ozone layer depletion.
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- 2018
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45. Classic polyarteritis nodosa presenting with acute anuric renal failure
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Candan, Cengiz, Civilibal, Mahmut, Oktay, Gulsah, Canpolat, Nur, Caliskan, Salim, Kilicaslan, Isin, Sever, Lale, Kasapcopur, Ozgur, and Arisoy, Nil
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- 2010
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46. Left ventricular function by ‘conventional’ and ‘tissue Doppler’ echocardiography in paediatric dialysis patients
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CIVILIBAL, MAHMUT, CALISKAN, SALIM, OFLAZ, HUSEYIN, SEVER, LALE, CANDAN, CENGİZ, CANPOLAT, NUR, KASAPCOPUR, OZGUR, and ARISOY, NIL
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- 2009
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47. Factors influencing children’s use of urban green spaces
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Işıl Kaymaz, Ozlem Candan Cengiz-Hergul, and Dicle Oguz
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03 medical and health sciences ,0302 clinical medicine ,Geography ,0211 other engineering and technologies ,Public Health, Environmental and Occupational Health ,Space use ,Physical activity ,021107 urban & regional planning ,030212 general & internal medicine ,02 engineering and technology ,Environmental design ,Socioeconomics ,Neighbourhood (mathematics) - Abstract
The purpose of this study was to investigate patterns and factors related to 6- to 12-year-old children’s and their parents’ green space use behaviours in Çayyolu neighbourhood of Ankara, Turkey. Data were collected through draw and write surveys and questionnaire surveys at selected schools, and direct observations in eight parks in the neighbourhood. A total of 418 children and 383 of their parents participated in the surveys. In all, 498 recordings were made during on-site observations. Findings suggest that there is an interaction between park visiting patterns of parents and their children. Taking children to parks was a major motivation for – particularly female (p
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- 2017
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48. Systemic lupus erythematosus due to Epstein–Barr virus or Epstein–Barr virus infection provocating acute exacerbation of systemic lupus erythematosus?
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Kasapcopur, Ozgur, Ergul, Yakup, Kutlug, Seyhan, Candan, Cengiz, Camcioglu, Yildiz, and Arisoy, Nil
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- 2006
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49. Rituximab treatment for difficult-to-treat nephrotic syndrome in children: A multicenter study
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Tasdemir, Mehmet, Canpolat, Nur, Yildiz, Nurdan, Ozcelik, Gul, Benzer, Meryem, Seha Kamil Saygili, Ozkayin, Nese, Turkkan, Ozde Nisa, Balat, Ayse, Candan, Cengiz, Celakil, Mehtap Ezel, Yavuz, Sevgi, Akinci, Nurver, Goknar, Nilufer, Akgun, Cihangir, Tulpar, Sebahat, Alpay, Harika, Sever, Lale, Bilge, Ilmay, TaSdemir, Mehmet, Bilge, Ilmay Koc Univ, Sch Med, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey, Canpolat, Nur, Saygili, Seha Kamil, Sever, Lale Istanbul Univ, Cerrahpaa Sch Med, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey, Yildiz, Nurdan, Alpay, Harika Marmara Univ, Sch Med, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey, Ozcelik, Gul, Akinci, Nurver Sisli Hamidiye Etfal Educ & Res Hosp, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey, Benzer, Meryem, Tulpar, Sebahat Bakirkoy Dr Sadi Konuk Educ & Res Hosp, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey, Ozkayin, Nese Trakya Univ, Sch Med, Div Pediat Nephrol, Dept Pediat, Edirne, Turkey, Turkkan, Ozde Nisa Istanbul Univ, Istanbul Sch Med, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey, Balat, Ayse Istanbul Aydin Univ, Sch Med, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey, Candan, Cengiz Istanbul Medeniyet Univ, Goztepe Educ & Res Hosp, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey, Celakil, Mehtap Ezel Kocaeli Univ, Sch Med, Div Pediat Nephrol, Dept Pediat, Kocaeli, Turkey, Yavuz, Sevgi Kanuni Sultan Suleyman Educ & Res Hosp, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey, Goknar, Nilufer Bagcilar Educ & Res Hosp, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey, and Akgun, Cihangir Istanbul Medipol Univ, Sch Med, Div Pediat Nephrol, Dept Pediat, Istanbul, Turkey
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Multicenter Study ,Nephrotic Syndrome ,Rituximab Treatment - Abstract
WOS: 000443998400408 …
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- 2018
50. Effects of nutritional Vitamin D supplementation on markers of bone and mineral metabolism in children with chronic kidney disease
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Cakar, N., Basin, E., Yalcinkaya, F., KARABAY BAYAZIT, AYSUN, Anarat, A., Laube, G., Bucher, B., Peco-Antic, A., Texeira, A., Donmez, O., Balat, A., Szczepanska, M., Niemirska, A., Litwin, M., Urasinski, T., Tkaczyk, M., Kiyak, A., Drodz, D., Zurowska, A., Azukaitis, K., Jankauskiene, A., Picca, S., Matteucci, C., Vidal, E., Testa, S., Lugani, F., Montini, G., Wigger, M., Kranz, B., Jeck, N., Wygoda, S., Pohl, M., Wuehl, E., Doyon, A., Schaefer, F., Thurn, D., Melk, A., Kemper, M., ÇALIŞKAN, Salim, Gimpel, C., Buescher, R., Galiano, M., Habbig, S., Querfeld, U., Zalosczyk, A., Fischbach, M., Ranchin, B., Harambat, J., Canpolat, N., Dusek, J., Arbeiter, K., Cortina, G., Haffner, Dieter, Candan, C., Schaefer, Franz, Sander, Anja, Leifheit-Nestler, Maren, Civilibal, M., Querfeld, Uwe, Melk, Anette, Rosales, Alejandra, Candan, Cengiz, Soylemezoglu, Oguz, Zaloszyc, Ariane, Habbig, Sandra, ALPAY, HARİKA, Emre, S., Alpay, H., Ozcelik, G., Kiyak, Aysel, Harambat, Jerome, Mir, S., Sozeri, B., Yalcinkaya, Fatos, Yilmaz, Ebru, Azukaitis, Karolis, Yavascan, O., DÜZOVA, ALİ, CANPOLAT, Nur, Niemirska, Anna, Tabel, Y., Ertan, P., Thurn, Daniela, KAPLAN BULUT, İPEK, Lerch, Christian, Yilmaz, E., Prytula, A., Bachetta, J., Haffner, D., Klaus, G., Gessner, M., Schmitt, C. P., Stabouli, S., Reusz, G., Verrina, E., Groothoff, J., Tondel, C., Gamero, M. A., Petrosyan, E., Dursun, I., Erdogan, H., Bilginer, Y., Soylemezoglu, O., Shroff, Rukshana, Shroff, R., Wan, Mandy, Bakkaloglu, SEVCAN AZİME, Aitkenhead, Helen, Rees, Lesley, Çukurova Üniversitesi, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, ARD - Amsterdam Reproduction and Development, Paediatric Nephrology, AGEM - Inborn errors of metabolism, APH - Quality of Care, APH - Methodology, Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School Children's Hospital, Hannover, Germany, Renal Unit, Great Ormond Street Hospital for Children, London, United Kingdom, Department of Chemical Pathology, Great Ormond Street Hospital for Children, London, United Kingdom, Department of Pediatric Nephrology, Ege University, Bornova, Izmir, Turkey, Department of Pediatric Nephrology, Faculty of Medicine, Cukurova University, Adana, Turkey, Department of Nephrology, Kidney Transplantation and Arterial Hypertension, Children's Memorial Health Institute, Warsaw, Poland, Department of Pediatrics, Istanbul University Cerrahpasa, Faculty of Medicine, Istanbul, Turkey, Division of Pediatric Nephrology, Hacettepe University, Faculty of Medicine, Ankara, Turkey, Clinic of Pediatrics, Faculty of Medicine, Vilnius University, Vilnius, Lithuania, Department of Pediatric Nephrology, Sanliurfa Children's Hospital, Sanliurfa, Turkey, Department of Pediatric Nephrology, School of Medicine, Ankara University, Ankara, Turkey, Department of Pediatrics, Bordeaux University Hospital, Bordeaux, France, Department of Pediatric Nephrology, Yenimahalle Egitim ve Arastirma Hastanesi Bakirkoy, Istanbul, Turkey, Department of Pediatric Nephrology, Marmara University School of Medicine, Istanbul, Turkey, Division of Pediatric Nephrology, University Children's, Adolescent's Hospital, Cologne, Germany, Pole Médico-Chirurgical de Pédiatrie, Service de Pédiatrie I, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Department of Pediatric Nephrology, Gazi University Hospital, Ankara, Turkey, Department of Pediatric Nephrology, Göztepe Egitim ve Arastirma Hastanesi, Cocuk Klinigi, Göztepe, Istanbul, Turkey, Department of Pediatrics, Innsbruck Medical University, Innsbruck, Austria, Clinic of Pediatric Nephrology, Charite Children's Hospital, Berlin, Germany, Institute of Medical Biometry and Informatics, University Heidelberg, Heidelberg, Germany, Division of Pediatric Nephrology, Heidelberg, Germany, Children's Hospital, Innsbruck, Austria, University Children's Hospital, Vienna, Austria, University Hospital Motol, Prague, Czech Republic, Hôpital des Enfants, Bordeaux, France, Hôpital Femme Mère Enfant, Université de Lyon, France, Hôpital de Hautepierre, Strasbourg, France, Charité Children's Hospital, Berlin, Germany, University Children's Hospital, Cologne, Germany, University Children's Hospital, Erlangen, Germany, University Children's Hospital, Essen, Germany, Center for Pediatrics and Adolescent Medicine, Freiburg, Germany, UKE University Children's Hospital, Hamburg, Germany, Hannover Medical School, Hannover, Germany, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany, Center for Pediatrics and Adolescent Medicine, Jena, Germany, City Hospital St. Georg, Leipzig, Germany, KfH Kidney Center for Children, Marburg, Germany, University Children's Hospital, Münster, Germany, Children's Hospital, Rostock, Germany, S. Orsola-Malpighi Hospital, Bologna, Italy, Istituto Giannina Gaslini, Genova, Italy, Fondazione Ospedale Maggiore Policlinico, Milano, Italy, Pediatric Nephrology, Dialysis and Transplant Unit, Padova, Italy, Ospedale Bambino Gesú, Rome, Italy, University Children's Hospital, Vilnius, Lithuania, Pediatric and Adolescent Nephrology, Gdansk, Poland, University Children's Hospital, Krakow, Poland, Polish Mothers Memorial Hospital Research Institute, Lodz, Poland, Clinic of Pediatrics, Szczecin, Poland, Children's Memorial Health Institute, Warsaw, Poland, Zabrze, Poland, Hospital Sao Joao, Porto, Portugal, University Children's Hospital, Belgrade, Serbia, Inselspital, Bern, Switzerland, University Children's Hospital, Zurich, Switzerland, Cukurova University, Adana, Turkey, University Faculty of Medicine, Ankara, Turkey, Baskent University, Faculty of Medicine, Ankara, Turkey, Diskapi Children's Hospital, Ankara, Turkey, Gazi University Hospital, Ankara, Turkey, Hacettepe Medical Faculty, Ankara, Turkey, Dortcelik Children's Hospital, Bursa, Turkey, Uludag University, Bursa, Turkey, University of Gaziantep, Turkey, Bakirkoy Children's Hospital, Istanbul, Turkey, Istanbul University Cerrahpasa, Faculty of Medicine, Istanbul, Turkey, Goztepe Educational and Research Hospital, Istanbul, Turkey, Haseki Educational and Research Hospital, Istanbul, Turkey, Istanbul Medical Faculty, Istanbul, Turkey, Marmara University Medical Faculty, Istanbul, Turkey, Sisli Educational and Research Hospital, Istanbul, Turkey, Ege University Medical Faculty, Izmir, Turkey, Tepecik Training and Research Hospital, Izmir, Turkey, Inonu University, Malatya, Turkey, Celal Bayar University, Manisa, Turkey, Ghent University, Utopaed, Belgium, University Children's Hospital, Lyon, France, University Children's Hospital, Marburg, Germany, University Children's Hospital, Tübingen, Germany, University Children's Hospital, Thessaloniki, Greece, Semmelweis University, Budapest, Hungary, G. Gaslini Institute, Genoa, Italy, Academic Medical Center, Amsterdam, Netherlands, University Children's Hospital, Bergen, Norway, Reina Sofia Universitary Hospital, Cordoba, Spain, Russian National Research Medical University, Moscow, Russian Federation, Erciyes University, Faculty of Medicine, Kayseri, Turkey, Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı., Dönmez, Osman, AAA-8778-2021, Lerch, Christian, Shroff, Rukshana, Wan, Mandy, Rees, Lesley, Aitkenhead, Helen, Bulut, Ipek Kaplan, Thurn, Daniela, Bayazit, Aysun Karabay, Niemirska, Anna, Canpolat, Nur, Duzova, Ali, Azukaitis, Karolis, Yilmaz, Ebru, Yalcinkaya, Fatos, Harambat, Jerome, Kiyak, Aysel, Alpay, Harika, Habbig, Sandra, Zaloszyc, Ariane, Soylemezoglu, Oguz, Candan, Cengiz, Rosales, Alejandra, Melk, Anette, Querfeld, Uwe, Leifheit-Nestler, Maren, Sander, Anja, Schaefer, Franz, Haffner, Dieter, Cortina, G., Arbeiter, K., Dusek, J., Harambat, J., Ranchin, B., Fischbach, M., Zalosczyk, A., Querfeld, U., Habbig, S., Galiano, M., Buescher, R., Gimpel, C., Kemper, M., Melk, A., Thurn, D., Schaefer, F., Doyon, A., Wuehl, E., Pohl, M., Wygoda, S., Jeck, N., Kranz, B., Wigger, M., Montini, G., Lugani, F., Testa, S., Vidal, E., Matteucci, C., Picca, S., Jankauskiene, A., Azukaitis, K., Zurowska, A., Drodz, D., Tkaczyk, M., Urasinski, T., Litwin, M., Niemirska, A., Szczepanska, M., Texeira, A., Peco-Antic, A., Bucher, B., Laube, G., Anarat, A., Bayazit, A. K., Yalcinkaya, F., Basin, E., Cakar, N., Soylemezoglu, O., Duzova, A., Bilginer, Y., Erdogan, H., Donmez, O., Balat, A., Kiyak, A., Caliskan, S., Canpolat, N., Candan, C., Civilibal, M., Emre, S., Alpay, H., Ozcelik, G., Mir, S., Sozeri, B., Yavascan, O., Tabel, Y., Ertan, P., Yilmaz, E., Shroff, R., Prytula, A., Bachetta, J., Haffner, D., Klaus, G., Gessner, M., Schmitt, C. P., Stabouli, S., Reusz, G., Verrina, E., Groothoff, J., Tondel, C., Gamero, M. A., Petrosyan, E., Bakkaloglu, S. A., and Dursun, I.
- Subjects
Male ,Fibroblast growth factor 23 ,Comorbidity ,urologic and male genital diseases ,Dietary supplement ,0302 clinical medicine ,Chronic kidney disease ,Chronic ,Child ,Klotho ,Children ,Clinical outcome ,Serum sclerostin ,Double blind procedure ,Vitamins ,Multicenter study ,female genital diseases and pregnancy complications ,3. Good health ,Clinical trial ,Bone and mineral metabolism ,Vitamin D deficiency ,Vitamin D supplementation ,Adolescent ,Alkaline Phosphatase ,Biomarkers ,Bone Density ,Double-Blind Method ,Female ,Fibroblast Growth Factors ,Follow-Up Studies ,Glomerular Filtration Rate ,Humans ,Renal Insufficiency, Chronic ,Vitamin D ,Dietary Supplements ,Blood ,Randomized controlled trial ,Nephrology ,Cohort analysis ,Human ,medicine.medical_specialty ,Mineral metabolism ,Sclerostin ,Clinical article ,Diet supplementation ,Article ,vitamin D deficiency ,Ergocalciferol ,03 medical and health sciences ,Cholecalciferol supplementation ,CKD ,Vitamin D and neurology ,Follow up ,medicine.disease ,Renal-failure ,Clinical effectiveness ,Endocrinology ,chemistry ,School child ,Chronic kidney failure ,Physiology ,Beta Glucuronidase ,Klotho Protein ,Chronic Kidney Disease-Mineral and Bone Disorder ,Fibroblast growth factor ,030232 urology & nephrology ,Medizin ,030204 cardiovascular system & hematology ,Growth-factor 23 ,chemistry.chemical_compound ,Randomized controlled trial (topic) ,Urology & nephrology ,Estimated glomerular filtration rate ,Renal Insufficiency ,Alpha-klotho ,Protein expression level ,Vitamin supplementation ,Priority journal ,Double-blind ,Klotho protein ,Glomerulus filtration rate ,medicine.drug ,Vitamin ,Bone metabolism ,Pathophysiology ,Hemodialysis-patients ,Internal medicine ,medicine ,Renal insufficiency, chronic ,FGF-23 ,Transplantation ,business.industry ,Alkaline phosphatase bone isoenzyme ,Fibroblast Growth Factor-23 ,Biological marker ,Metabolism ,business ,Controlled study ,Kidney disease - Abstract
PubMedID: 29481636 Background: We investigated the effects of nutritional vitamin D supplementation on markers of bone and mineral metabolism, i.e. serum levels of fibroblast growth factor 23(FGF23), Klotho, bone alkaline phosphatase (BAP) and sclerostin, in two cohorts with chronic kidney disease (CKD). Methods: In all, 80 vitamin D-deficient children were selected: 40 with mild to moderate CKD from the ERGO study, a randomized trial of ergocalciferol supplementation [estimated glomerular filtration rate (eGFR) 55 mL/min/1.73 m 2 ], and 40 with advanced CKD from the observational Cardiovascular Comorbidity in Children with Chronic Kidney Disease (4C) study (eGFR 24 mL/min/1.73 m 2 ). In each study, vitamin D supplementation was started in 20 children and 20 matched children not receiving vitamin D served as controls. Measures were taken at baseline and after a median period of 8 months. Age- and gender-related standard deviation scores (SDSs) were calculated. Results: Before vitamin D supplementation, children in the ERGO study had normal FGF23 (median 0.31 SDS) and BAP (-0.10 SDS) but decreased Klotho and sclerostin (-0.77 and - 1.04 SDS, respectively), whereas 4C patients had increased FGF23 (3.87 SDS), BAP (0.78 SDS) and sclerostin (0.76 SDS) but normal Klotho (-0.27 SDS) levels. Vitamin D supplementation further increased FGF23 in 4C but not in ERGO patients. Serum Klotho and sclerostin normalized with vitamin D supplementation in ERGO but remained unchanged in 4C patients. BAP levels were unchanged in all patients. In the total cohort, significant effects of vitamin D supplementation were noted for Klotho at eGFR 40-70mL/min/1.73m 2 . Conclusions: Vitamin D supplementation normalized Klotho and sclerostin in children with mild to moderate CKD but further increased FGF23 in advanced CKD. © The Author(s) 2018. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. American Society of Pediatric Nephrology: ESPN 2014.3 This work was supported by the European Society for Pediatric Nephrology (reference number ESPN 2014.3), KfH Foundation for Preventive Medicine and ERA-EDTA (to D.H.).
- Published
- 2018
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