Author: "C. O’Herlihy" - Searchworks@Jio Institute Digital Library Search Results

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228 results on '"C. O’Herlihy"'

1. 59 An investigation of global longitudinal strain in primary mitral regurgitation: a retrospective cohort of patients with mitral regurgitation

Author: M Hinds, DM Kerins, C O’Herlihy, A Amaro, R Lavery, and C Vaughan
Subjects: medicine.medical_specialty, Mitral regurgitation, Longitudinal strain, business.industry, Internal medicine, medicine, Cardiology, Retrospective cohort study, business
Published: 2018
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2. Postpartum anal sphincter dysfunction

Author: M. Fitzpatrick and C. O’Herlihy
Subjects: medicine.medical_specialty, Pelvic floor, medicine.diagnostic_test, business.industry, Incidence (epidemiology), Obstetrics and Gynecology, Physical examination, medicine.disease, Surgery, Menopause, medicine.anatomical_structure, Endoanal ultrasound, medicine, Tears, Childbirth, business, Anal sphincter
Abstract: Faecal incontinence presents with a female to male ratio of 8:1 suggesting childbirth as the principal causative factor, although most women do not become symptomatic until after menopause. Obstetric injury may arise as a result of direct muscular damage to the anal sphincter, as occurs during a third-degree tear, and/or may be the result of cumulative damage to the pudendal nerves. Symptomatic women should be assessed in a dedicated clinic where time is available for comprehensive evaluation. Clinical examination alone may fail to detect specific abnormalities. The performance of anal manometry, endoanal ultrasound and neurophysiology studies of the pelvic floor will increase the diagnostic yield. Treatment may include dietary manipulation and physiotherapy. In severe cases surgery may be warranted with secondary repair of the anal sphincter muscle. Adequate primary management of third-degree tears requires careful appraisal so as to reduce the incidence of later incontinence.
Published: 1999
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3. Irish endocrine society: 23rd annual meeting

Author: W. J. Kokaly, T. J. McKenna, W. M. Kong, D. O’sShea, J. Alaghband-Zadeh, J. Jones, G. Carter, P. P. A. Smyth, C. O’Herlihy, J. H. Lazarus, L. D. K. E. Premawardhana, A. B. Parkes, C. S. Kularatna, A. Rees, J. Evans, C. Wijeyaratne, H. Da Silva, A. Gleeson, K. Anderton, D. Owens, P. Collins, A. Johnson, G. H. Tomkin, D. Smith, F. Finucane, K. McKenna, J. Finucane, C. J. Thompson, J. Phillips, E. M. McConnell, A. B. Atkinson, C. Ennis, D. R. McCance, D. R. Hadden, B. Sheridan, P. M. Bell, A. M. Suliman, F. Al-Saber, F. Hayes, T. Fiad, M. Culliton, S. Cunningham, T. P. Smith, W. Campbell, C. F. Johnston, W. J. Curry, K. D. Buchanan, A. C. Leary, G. Grealy, T. M. Higgins, N. Buckley, D. G. Barry, J. B. Ferriss, K. M. S. McNeill, R. T. Cunningham, J. A. O’Hare, P. Burke, P. Grace, E. Murphy, J. Reynolds, J. J. Nolan, N. N. Chan, D. Darko, A. Jackson, W. S. Dhillo, D. O’Shea, M. T. Kilbane, R. A. Ajjan, A. P. Weetman, S. G. Shering, E. W. M. McDermott, N. J. O’Higgins, ÁA. N. Johansson, D. O’Kane, J. D. Allen, C. H Courtney, A. S. McAllister, B. T. Kinsley, T. Smith, J. MacMahon, H. Leslie, D. Cannon, D. Powell, C. H. Courtney, P. T. McSorley, C. N. Ennis, I. S. Young, and J. P. H. Fee
Subjects: Sodium-iodide symporter, medicine.medical_specialty, business.industry, Thyroid, Cancer, General Medicine, medicine.disease, Endocrinology, medicine.anatomical_structure, Cell culture, Internal medicine, medicine, Endocrine system, skin and connective tissue diseases, business, Receptor, Incubation, Thyroid cancer
Abstract: C CLARKE, CG BRENNAN, K RODGERS, RM DWYER, PPA SMYTH ENDOCRINE LABORATORY, DEPARTMENT OF MEDICINE AND THERAPEUTICS, UNIVERSITY COLLEGE DUBLIN, IRELAND he demonstration in extrathyroidal human tissues of the sodium iodide symporter (NIS) has raised the possibility that 1311, commonly used as a systemic therapeutic ablative agent in hyperthyroidism and thyroid cancer, might be applied in the treatment of tumours in other NISexpressing tissues such as human breast cancer. Thyroidal transport of 1311 is known to be proportional to circulating stable I and the aim of this study was to determine how stable I (KI) would effect such transport in human breast cancer cell lines MDA-MB-231, MCF-7 and in FRTL-5 thyroid cells. All cells were incubated with KI (01 00mM) for 72 hours after which 1Th I was added . Incubation and uptake of 'l by cells was counted every four hours. Timed efflux of '^I was measured every five minutes. KI in the incubation medium blocked 1251 uptake in a dose-dependent manner in the E receptor positive MCF7 cell line. The effect was less marked in the E receptor negative MDA-MB-231 with significant uptake being maintained even at an I concentration of 50mM. A similar blockade was seen in the FRTL-5 cells with maximum uptake blockade of 25mM I. The rate of efflux of 15I was similar in both MCF-7 and MDA-MB-231 cell lines with a tin of 35 and 40 minutes respectively. In contrast, efflux from the FRTL-5 cells was faster (tire=15 mins). As the human breast has a much lower avidity for I than the thyroid, control of dietary intake would assume even greater importance in radioactive iodine treatment of breast tumours or their metastases.
Published: 1998
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4. National scientific medical meeting 1997 abstracts

Author: H. J. Willison, A. J. Lastovica, M. M. Prendergast, A. P. Moran, C. Walsh, I. Flitcroft, P. Eustace, C. McMahon, J. Smith, O. P. Smith, G. Lakshmandass, M. R. H. Taylor, C. V. Holland, D. Cox, B. Good, G. M. Kearns, P. Gaffney, K. Shark, M. Frauenshuh, W. Ortmann, R. Messner, R. King, S. Rich, T. Behrens, N. Mahmud, A. Molloy, J. McPartlin, J. M. Scott, D. G. Weir, K. M. Walsh, D. Thorburn, P. Mills, A. J. Morris, T. Good, S. Cameron, E. A. B. McCruden, M. W. Bennett, J. O’Connell, C. Brady, D. Roche, J. K. Collins, F. Shanahan, G. C. O’Sullivant, M. Henry, S. Koston, K. McMahon, W. MacNee, M. X. FitzGerald, C. M. O’Connor, D. McGonagle, W. Gibbon, P. O’Connor, P. Emery, M. Murphy, R. Watson, E. Casey, E. Naidu, L. Barnes, S. McCann, E. Sweeney, E. J. Barrett, H. Graham, R. T. Cunningham, C. F. Johnston, W. J. Curry, K. D. Buchanan, C. H. Courtney, A. S. McAllister, D. R. McCance, D. R. Hadden, P. M. Bell, H. Leslie, B. Sheridan, A. B. Atkinson, M. T. Kilbane, D. F. Smith, M. J. Murray, S. G. Shering, E. W. M. McDermott, N. J. O’Higgins, P. P. A. Smyth, J. McEneny, E. R. Trimble, I. S. Young, P. Sharpe, C. Mercer, D. McMaster, A. E. Evans, J. Cundick, O. Hasselwander, J. McGeough, D. Savage, A. P. Maxwell, F. Kee, C. J. Larkin, R. G. P. Watson, C. Johnston, J. E. S. Ardill, D. A. McNamara, T. N. Walsh, D. J. Bouchier-Hayes, C. Madden, C. Timon, N. Gardiner, M. Lawler, J. O’Riordan, C. Duggan, S. R. McCann, H. Gowing, E. Braakman, C. Byrne, A. C. M. Martens, A. Hagenbeek, N. Kinsella, S. Cusack, H. Baker, B. White, K. Molloy, A. Wogan, S. McElwaine, D. Hollywood, C. Mcmahon, C. Merry, M. Ryan, O. Smith, F. M. Mulcahy, C. Murphy, J. Briones, P. Lavin, M. McCaffrey, P. Gillen, L. Thompson, M. Lalloz, M. Layton, C. Corish, N. P. Kennedy, P. Flood, S. Mulligan, E. McNamara, P. M. Mathias, E. Ball, D. Duiculescu, P. Calistru, N. O’Gorman, M. Abuzakouk, C. Feighery, M. Brannigan, S. Pender, F. Keeling, J. Varghese, M. Lee, M. Colreavy, R. Gaffney, S. Hone, M. Herzig, M. Walsh, C. Dolan, D. Donovan, J. Harmey, A. Haverty, J. H. Wang, J. H. Harmey, H. P. Redmond, G. McGreal, M. J. Moriarty, A. Shortt, E. Kay, G. Pidgeon, P. Dunne, H. Lambkin, J. M. Russell, A. J. O’Neill, B. M. Dunne, M. O’Donovan, E. F. Gaffney, J. E. Gillan, T. G. Cotter, J. Horan, D. Jones, S. K. Biswas, E. C. Mulkerrin, H. Brady, J. O’Donnell, J. Neary, E. Healy, A. Watson, B. Keogh, C. Cassidy, S. Ward, E. Stokes, F. Keoghan, A. Barrett, P. O’Connell, N. Ryall, P. A. O’Connell, A. Jenkinson, T. O’Brien, P. G. O’Connell, R. Harrison, T. Barrett, D. M. D. Bailey, A. Butler, D. E. Barton, G. Daly, M. Gill, S. Heron, Z. Hawi, M. Fitzgerald, L. Mynett-Johnson, D. Shiels, K. Kendler, P. McKeon, R. Straub, D. Walsh, F. Ryan, D. McCabe, R. Murphy, R. Segurado, T. Mulcahy, B. Larson, C. Comerford, R. O’Connell, E. O’Mahony, J. Donnelly, F. Minahan, D. O’Neill, Z. Farrell, C. Glynn, E. Mulkerrin, S. E. Lennox, A. Murphy, I. M. Rea, H. McNulty, C. McMeel, H. McEvoy, R. Freaney, M. J. McKenna, M. Crowe, D. Keating, G. Norman, S. Widda, L. Viani, null Galvin, C. M. Nolan, O. Hardiman, F. Brett, O. Droogan, P. Gallagher, M. Harmey, M. King, J. Murphy, R. Perryrnan, S. Sukumaran, J. Walsh, M. A. Farrell, G. Hughes, C. Cunningham, J. B. Walsh, D. Coakley, M. Hurson, P. McMonagle, S. O’Sullivan, P. Dodd, J. Redmond, R. Browne, S. Keating, J. O’Connor, B. P. Cassidy, R. Smyth, N. P. Sheppard, R. Cullivan, J. Crown, N. Walsh, A. Denihan, I. Bruce, A. Radic, B. A. Lawlor, P. K. Bridges, M. O’Doherty, A. Farrington, B. Farragher, S. Fahy, R. Kelly, T. Carey, J. Owens, O. Gallagher, D. Sloan, C. McDonough, P. Casey, A. Horgan, A. Elneihum, C. O’Neill, T. McMonagle, J. Quinn, D. Meagher, P. Murphy, A. Kinsella, J. Mullaney, J. L. Waddington, S. Rooney, L. Bamford, J. J. O’Connor, R. Franklin, K. O’Brien, G. Fitzpatrick, J. G. Laffey, J. F. Boylan, J. Laffey, M. Coleman, J. Boylan, A. J. McShane, J. P. R. Loughrey, J. Gardiner, J. McGinley, I. Leonard, M. Carey, P. Neligan, J. O’Rourke, A. Cunningham, F. Fennessy, C. Kelly, D. Bouchier-Hayes, J. Kellett, D. Murphy, J. Regan, D. O’Keeffe, A. Mahmud, L. Hemeryck, J. Feely, M. Hall, I. B. A. Menown, T. P. Mathew, G. S. Nesbitt, M. Syme, A. A. J. Adgey, F. Turtle, J. Allen, J. Anderson, R. O’Hanlon, M. B. Codd, S. Walkin, H. A. McCann, D. D. Sugrue, A. M. Rasheed, G. Chen, A. Leahy, S. Jina, I. McDowell, Q. Wo, M. N. Shuhaibar, E. McGovern, G. Manoharan, R. Kirkpatrick, N. P. S. Campbell, C. McCarthy, Y. Wen, S. Killalea, C. J. Fahy, A. Griffith, A. Fraser, T. Ryan, M. Browne, J. Fenton, J. Hughes, C. I. Timon, A. Curran, D. Smyth, J. P. Hughes, P. Lee, A. Kelly, N. Shine, A. Blayney, D. P. McShane, J. Hussey, M. Howlett, A. Langton, A. McEvoy, J. Slevin, C. Fitzpatrick, M. J. Turner, F. Enright, N. Goggin, C. Costigan, D. Duff, P. Osizlok, F. Wood, R. B. Fitzsimons, N. Flanagan, E. Molloy, E. Griffin, P. F. Deasy, M. Sheridan, M. J. White, R. Moore, A. Gray, J. Hill, J. F. T. Glasgow, B. Middleton, D. Slattery, V. Donoghue, A. McMahon, A. McCarthy, P. Oslislok, I. Keogh, K. J. Russell, M. X. Fitzgerald, P. V. Kavanagh, S. M. McNamara, M. Barry, J. E. O’Brien, P. McCormick, C. Molony, R. M. Doyle, P. R. O’Connell, L. C. Dowey, H. McGlynn, D. I. Thurnham, S. J. Elborn, L. Flynn, J. Carton, B. Byrne, C. O’Farrelly, P. Kelehan, C. O’Herlihy, A. M. O’Hara, A. Orren, B. A. Fernie, S. Clarke, G. Courtney, C. de Gascun, M. Byrne, E. Moylett, H. Murphy, K. Butler, C. Nourse, H. Thaker, C. Barry, J. Russell, G. Sheehan, B. Boyle, R. Hone, B. Conboy, C. Butler, D. Moris, M. Cormican, J. Flynn, O. McCormack, N. Corbally, A. Murray, S. Kirrane, C. O’Keane, S. M. Lynch, B. Cryan, D. Whyte, D. Morris, G. Corbett-Feeney, T. Mackle, J. Perkins, C. Saidlear, A. Young, M. Wrigley, J. Clifford, O. Tighe, D. T. Croke, J. Drago, D. R. Sibley, M. Carvalho, M. Hennessy, M. Kelly, C. Hughes, M. Hanlon, K. Sabra, T. Keane, D. Egan, C. Maerry, S. C. Sharma, D. Williams, N. G. Mahon, G. M. Sayers, and Z. Johnson
Subjects: Medical education, business.industry, Medicine, General Medicine, business
Published: 1998
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5. Sylvester o’halloran surgical scientific meeting

Author: G. J. Fulton, M. G. Davies, P. O’Hagen, A. Rasheed, C. Kelly, E. Kay, S. Fitzgerald, D. Bouchier-Hayes, A. Leahy, F. Fennessy, P. Fitzgerald, K. Khosraviani, H. P. Weir, K. Williamson, R. Wilson, R. J. Moorehead, B. J. Rowlands, D. Morrissey, J. O’Connell, D. Lynch, C. O’Sullivan, F. Shanahan, J. K. Collins, J. L. Kelly, C. C. Soberg, A. Lyons, J. A. Mannick, J. A. Lederer, C. Chen, D. J. Bouchier-Hayes, H. Fitzsimons, D. M. O’Hanlon, C. Curran, M. Canney, S. Morris, O. Clinton, H. F. Given, E. Coveney, H. K. Lyerly, F. L. Murphy, C. J. Kelly, D. H. Osborne, P. Kelly, D. S. O’Riordan, P. G. Horgan, F. B. V. Keane, W. A. Tanner, P. Kilmartin, C. P. Delaney, S. M. Johnston, J. M. Fitzpatrick, T. F. Gorey, J. Mehigan, M. G. O/rsRiordan, N. Shines, A. Hill, C. O. McDonnell, F. Murphy, S. M. Javadpour, Y. Alhadi, R. Waldron, R. G. Watson, A. Tarrant, T. K. Neelamekam, J. Mathias, J. Geoghegan, T. Boyle, O. Traynor, S. Hayes, B. O’Donovan, N. Ajmal, J. McCann, N. T. Corrigan, M. G. O’Riordan, P. Ross, M. O’Donohoe, M. Bresnihan, T. M. Feeley, C. Fiuza-Castineira, D. Coleman, H. Fisher, A. Butt, E. Ghumman, P. Grace, P. Burke, S. A. Martin, M. K. Fox-Talbot, P. A. Lipsett, K. D. Lillemoe, H. A. Pitt, D. A. O’Keeffe, A. D. K. Hill, K. Sheahan, F. Ryan, D. Barton, R. Fitzgerald, E. W. McDermott, N. J. O’Higgins, E. Kavanagh, P. Kiely, D. O’Driscoll, M. Ramesh, W. O. Kirwan, D. C. Winter, K. Nally, J. O’Callaghan, J. B. Matthews, B. J. Harvey, G. C. O’Sullivan, L. S. Young, M. C. Regan, P. Sweeney, D. M. Bouchier-Hayes, R. Dardis, P. Broe, M. G. O’Brien, P. Neary, P. Ridgeway, C. Condron, J. H. Wang, H. P. Redmond, D. R. M. Redfern, R. K. S. Strachan, J. M. Hollingdale, P. A. Grace, A. Acheson, A. Graham, C. Weir, B. Lee, C. O’Donnell, D. Buckley, J. A. O’Donnell, E. Purcell, M. O’Donoghue, S. Sultan, M. Colgan, M. Molloy, D. Moore, G. Shanik, P. T. McCollum, Z. Raza, S. Naidu, P. A. Stonebridge, M. P. Colgan, D. J. Moore, D. G. Shanik, J. Dowdall, C. Williams, S. G. Shering, G. Duffy, R. Greengrass, D. Iglehart, G. Little, H. Kim Lyerly, M. Fynes, A. Cahill, C. O’Herlihy, P. R. O’Connell, I. Ahmad, M. Etisham, J. Drumm, H. Flood, K. Mulhall, K. Murray, S. O’Rian, N. Garvey, J. Johnston, G. T. McGreal, M. P. Brady, M. M. Duffy, M. Regan, M. G. Harrington, M. Javadpour, C. McDonnell, E. Eguare, M. C. Barry, G. C. O’Toole, N. O’Higgins, E. McDermott, C. M. Brady, S. A. Sultan, M. K. O’Donoghue, M. P. Molloy, G. D. Shanik, R. J. Holdsworth, M. Fehily, C. Doran, F. Keane, J. F. Rothwell, M. J. Staunton, L. O’Mahony, E. F. Gaffney, K. Mealy, T. P. J. Hennessy, and J. Geibel
Subjects: business.industry, Art history, Medicine, General Medicine, business
Published: 1998
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6. Irish Society of Gastroenterology

Author: M. Woods, L. J. D. O’Donnell, B. Battistini, T. Warner, J. Vane, M. G. Fartming, J. Yaqoob, J. J. Wu, L. A. Norris, M. I. Khan, P. W. N. Keeling, D. Maguire, G. O’Sullivan, B. Harvey, B. Curran, Y. Xin∘, E. W. Kay, M. Leader, K. Henry, O. Crosbie, S. Norris, P. Costello, C. O’Farrelly, J. Hegarty, B. Kennedy, M. Duggan, R. Plant, E. K. Kenny-Walsh, P. Cotter, M. J. Whelton, M. Maloney, N. Noonan, M. Buckley, H. Hamilton, S. Beattie, C. O’Morain, B. McNamara, J. Cuffe, R. A. Barry, D. A. Collins, G. C. O’Sullivan, J. K. Collins, F. Shanahan, M. M. Skelly, H. E. Mulcahy, A. Troy, T. Connell, C. Duggan, M. J. Duffyt, K. Sheahan, D. P. O’Donoghue, H. X. Xia, D. Hyde, M. G. O’Brien, E. F. Fitzgerald, G. Lee, A. J. Hussey, T. J. Boyle, B. Garrihy, O. P. Clinton, O. J. McAnena, G. O’Sulllvan, H. Corby, V. Donnelly, C. O’Herlihy, P. R. O’Connell, T. Deignan, J. Kelly, N. P. Breslin, C. MacDonnell, J. O’Keeffe, K. Mills, U. Srinivasan, R. Willoughby, C. Feighery, B. Twohig, K. Gaynor, P. F. O’Regan, S. Duggan, H. P. Redmond, J. McCarthy, D. Bouchier-Hayes, Q. Y. Ma, K. E. Williamson, B. J. Rowlands, A. Tobin, R. Pilkington, M. O’Donnell, E. O’Shea, A. Conroy, G. Kaminski, A. Walsh, I. J. Temperley, D. Kelleher, D. G. Weir, M. K. Barry, E. D. Mulligan, M. A. Stokes, M. G. O’Riordain, T. F. Gorey, K. F. McGeeney, J. M. Fitzpatrick, R. W. G. Watson, J. H. Wang, F. Campbell, D. Bennett, E. Kavanagh, P. O. Gorman, P. O’Regan, M. M. I. Yassin, M. McCaigue, T. G. Parks, A. A. B. Barros D’Sa, M. Lawlor, S. McElwaine, M. A. Heneghan, M. Kerins, J. Goulding, E. L. Egan, F. M. Stevens, C. F. McCarthy, M. Quirke, A. M. Eustace-Ryan, S. Qureshi, E. Aziz, A. Maree, S. Collins, T. Browne, S. Ahmed, B. O. Sullibhan, P. Smith, F. Walker, F. O’Connor, E. Sweeney, R. J. Farrell, M. Morrint, M. Goggins, and J. G. McNulty
Subjects: medicine.medical_specialty, Irish, business.industry, Ophthalmology, language, medicine, Library science, General Medicine, business, language.human_language
Published: 1995
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7. Gynaecological audit in a general hospital setting

Author: G. Connolly, P. McKenna, Barbara Coughlan, and C. O’Herlihy
Subjects: Patient Transfer, Medical Audit, Pediatrics, medicine.medical_specialty, Waiting Lists, business.industry, Genitalia, Female, General Medicine, Audit, Hospitals, General, medicine.disease, United Kingdom, Patient Admission, Postoperative Complications, medicine, Humans, Female, Medical emergency, General hospital, Emergency Service, Hospital, Obstetrics and Gynecology Department, Hospital, business, Genital Diseases, Female, Ireland
Abstract: In contrast to the long tradition of audit in Obstetrics in Dublin audit in Gynaecology is a new concept. Analysis of data collected during the years 1991-1993 is presented. This has addressed the number and type of patients seen in the Gynaecology Unit, procedures performed and complications ensuing. The figures presented are similar to Gynaecology Units in Britain. Deficiencies, such as auditing for outpatient and inpatient waiting lists have been highlighted. These issues are currently being addressed.
Published: 1995
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8. Irish Society of Gastroenterology

Author: P. K. Neelamakam, E. Brazil, S. Attwood, O. Traynor, J. Yaqoob, M. I. Khan, D. O’Toole, N. Noonan, C. Carey, D. Kelleher, D. G. Weir, P. W. N. Keeling, D. Monahan, L. Cogan, R. Willoughby, J. Jackson, A. Whelan, C. Feighery, G. Z. Kaminski, A. Conroy, S. Dooley, N. A. Parfrey, P. McEneaney, C. O’Morain, J. P. McGrath, R. C. Stuart, J. Hill, P. J. Byrne, C. Timon, S. C. S. Chung, A. VanHasselt, T. P. J. Hennessy, D. Hamilton, D. Mulcahy, D. Walsh, C. Farrely, W. Tormey, J. Fielding, G. Watson, A. Cherukuri, M. Maloney, D. O. Toole, M. Corcoran, J. Coffey, F. Butt, D. McAvinchey, P. V. Delaney, G. J. Burke, S. Youngprapakorn, U. Srinivasan, N. Leonard, C. O’Farrelly, C. O. Morain, C. A. Whelan, E. Barry, C. Collins, P. Costello, C. O’Herlihy, D. P. O’Donoghue, C. Clabby, J. McCarthy, E. Kenny-Walsh, M. J. Whelton, M. Morrin, F. Khan, P. Delaney, J. O’Keeffe, K. Mills, M. A. Bennett, E. W. Kay, H. Mulcahy, M. Leader, D. T. Croke, X. G. Fan, I. Khan, S. Keating, C. Morrison, M. Buckley, F. M. O’Reilly, C. Darby, M. G. Courtney, G. M. Murphy, J. F. Fielding, C. J. O’Boyle, T. J. Boyle, K. Mulhall, M. J. Kerin, D. Courtney, D. S. Quill, H. F. Given, S. Kehoe, R. Quirke, R. B. Stephens, S. Norris, G. McEntee, J. Hegarty, C. Farrelly, D. Thottaparambil, R. Thomas, G. Houghton, S. Sachithanandan, A. Geoghegan, S. Doyle, C. McCaul, T. N. Walsh, R. Farrell, B. Gusau, M. S. O’Mahoney, S. AlBloushi, J. Sachithanandan, J. Walshe, M. Carmody, J. Donohoe, A. G. Shattock, N. Parfrey, S. Lynch, L. Madrigal, J. McEntee, R. Murphy, Z. Ahmed, M. Ryan, C. Montwill, A. Morgan, P. Smith, F. Walker, A. Murphy, M. Moloney, S. McGrath, E. Taraneweh, A. K. Bhatia, D. O’Keeffe, P. McCarthy, E. Rajan, S. Albloushi, B. O’ Farrell, A. Shattock, D. Kearney, J. Lee, F. Gleeson, B. McNamara, J. Cuffe, G. C. O’Sullivan, B. J. Harvey, B. Curran, E. Kay, L. Lawler, S. E. A. Attwood, G. Bourke, J. Hyland, W. A. Owens, C. M. Loughrey, J. A. McAleer, K. G. McManus, J. F. Dillon, F. C. Wong, T. C. N. Lo, K. H. Chan, J. N. Plevris, N. D. C. Finlayson, J. D. Miller, I. A. D. Bouchier, P. C. Hayes, S. V. Walsh, L. J. Egan, C. E. Connolly, F. M. Stevens, E. L. Egan, C. F. McCarthy, Q. Y. Ma, G. D. Magee, J. E. Ardill, K. D. Buchanan, B. J. Rowlands, P. McGettigan, R. Chan, B. O’ Shea, J. McManus, J. Feely, J. Donoghue, N. Fanning, J. Mathias, P. Gillen, W. A. Tanner, F. B. V. Keane, D. M. Campbell, V. Donnelly, D. O’Connell, M. Behan, P. R. O’Connell, C. S. Ko, K. Mealy, B. M. Gusau, M. Goggins, J. Yakoub, R. J. Farrell, and N. Mahmud
Subjects: medicine.medical_specialty, Irish, business.industry, Ophthalmology, medicine, language, Library science, General Medicine, business, language.human_language
Published: 1995
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9. National scientific medical meeting 1995 abstracts

Author: S. Norris, C. Collins, J. Hegarty, C. O’Farrelly, J. Carton, L. Madrigal, D. P. O’Donoghue, H. Holloway, J. F. Fielding, W. Mullins, S. W. Hone, M. Donnelly, F. Powell, A. W. Blayney, E. A. Cahill, S. F. Daly, M. J. Turner, P. A. Sullivan, M. McLoughlin, M. M. Skelly, H. E. Mulcahy, T. Connell, C. Duggan, M. J. Duffy, A. Troy, K. Sheahan, A. Whelan, C. M. Herra, C. T. Keane, H. Johnson, B. Lee, E. Doherty, T. McDonnell, D. Mulherin, O. FitzGerald, B. Bresnihan, H. M. Hassett, A. Boyce, V. Greig, C. O’Herlihy, P. P. A. Smyth, E. F. Roche, I. McCormack, E. Tempany, M. J. Cullen, D. F. Smith, Y. McBrinn, B. Murray, R. Freaney, D. Keating, M. J. McKenna, J. A. O’Hare, H. Alam, Q. Raza, M. Geoghegan, S. Killalea, M. Hall, J. Feely, L. Kyne, B. O’Hara, M. Cullen, I. M. Rea, J. P. Donnelly, R. W. Stout, P. Lacey, M. J. Donnelly, J. McGrath, T. P. Hennessy, C. V. I. Timon, D. Hyde, H. X. Xia, M. Buckley, C. O’Morain, S. Keating, H. Xia, J. P. McGrath, R. C. Stuart, P. Lawlor, P. J. Byrne, T. N. Walsh, T. P. J. Hennessy, M. Duffy, M. Tubridy, J. Redmond, K. Monahan, R. P. Murphy, D. R. Headon, T. O’Gorman, F. M. O’Reilly, C. Darby, G. M. Murphy, A. Murphy, M. Codd, P. Dervan, D. Lawlor, S. O. Loughlin, N. Flanagan, R. Watson, L. Barnes, C. Kilgallen, E. Sweeney, A. Mynes, D. Mooney, I. Donoghue, O. Browne, J. A. Kirrane, D. McKenna, M. Young, E. O’Toole, S. O’Briain, U. Srinivasan, C. Feighery, N. Leonard, E. Jones, M. A. Moloney, D. G. Weir, M. Lawler, A. O’Neill, H. Gowing, D. Pamphilon, S. R. McCann, G. O’Toole, A. Orren, C. M. Seifer, D. C. Crowley, G. J. Sheehan, T. Deignan, J. Kelly, V. J. Tormey, J. Faul, C. Leonard, C. M. Burke, L. W. Poulter, S. Lynch, G. McEntee, O. Traynor, E. Barry, P. Costello, A. Keavney, R. Willoughby, C. O’Donnell, M. Cahill, A. Earley, P. Eustace, R. Osborne, C. Saidlear, B. Holmes, A. Early, A. P. Moran, A. Neisser, R. J. Polt, H. Bernheimer, M. Kainz, B. Schwerer, L. Gallagher, R. Firth, N. Kennedy, E. McGilloway, N. Tubridy, K. Shields, W. K. Cullen, M. J. Rowan, A. R. Moore, M. Rowan, D. Coakley, B. Lawlor, G. Swanwick, R. Al-Naeemi, R. Murphy, N. M. Codd, M. Goggins, N. P. Kennedy, B. L. Mallon, H. Mulcahy, M. Skelly, D. O. Donoghue, D. McCarthy, A. Saunders, D. J. Veale, J. J. F. Belch, D. Breathnach, E. Murphy, G. Kernohan, K. Gibson, A. G. Wilson, G. W. Duff, N. de Vries, L. B. A. van de Putte, J. Donoghue, F. O’Kelly, Z. Johnson, T. Maher, A. Moran, C. Keane, D. O’Neill, N. Horgan, J. M. Barragry, D. M. Campbell, M. Behan, P. R. O’Connell, V. S. Donnelly, D. Crowley, M. Geary, P. Boylan, M. Fanagan, K. Hickey, T. Teoh, M. Doyle, R. Harrison, D. Lyons, Y. Shenouda, M. Coughlan, P. McKenna, P. Lenehan, M. Foley, P. Kelehan, P. Ravichandran, M. Kelly, A. Conroy, C. Fitzpatrick, D. Egan, C. L. Regan, B. V. McAdam, P. McParland, G. A. FitzGerald, D. J. Fitzgerald, S. C. Sharma, K. Foran, C. Barry-Kinsella, R. F. Harrison, F. J. Gillespie, P. O’Mahony, M. Boyle, M. J. White, F. Donohoe, Y. Birrane, M. Naughton, R. B. Fitzsimons, M. Piracha, S. McConkey, E. Griffin, E. Hayes, T. Clarke, N. Parfrey, K. Butler, A. J. Malone, P. J. Kearney, P. F. Duggan, A. Lane, R. Keville, M. Turner, S. Barry, D. Sloan, S. Gallagher, M. Darby, P. Galligan, J. Stack, N. Walsh, M. O’Sullivan, M. Fitzgerald, D. Meagher, S. Browne, C. Larkin, P. Casey, E. O’Callaghan, S. Rooney, E. Walsh, M. Morris, T. Burke, M. Roe, C. Maher, M. Wrigley, M. Gill, M. Burgess, E. Corcoran, D. Walsh, B. Gilmer, C. B. Hayes, L. Thornton, J. Fogarty, R. Lyons, M. O’Connor, V. Delaney, K. Buckley, D. Lillis, V. Delany, C. Hayes, P. Dack, D. Igoe, H. J. O’Neill, P. Kelly, D. McKeown, L. Clancy, G. Varghese, S. Hennessy, J. J. Gilmartin, K. Birthistle, D. Carrington, H. Maguire, P. Atkinson, C. Foley-Nolan, M. Lynch, B. Cryan, D. Whyte, C. Conlon, V. Kucinskas, U. Usinskiene, I. Sakalyte, E. Dawson, K. Molloy, N. Goulden, J. Doyle, E. Lawlor, M. G. Harrington, N. El-Nageh, M. -L. Nolan, J. O’Riordan, G. Judge, G. Crotty, T. Finch, M. Borton, T. Barnes, O. Gilligan, G. Lee, R. Limmer, M. Madden, C. Bergin, A. O’Leary, F. Mulcahy, F. Wallis, M. Glennon, M. Cormican, U. NiRiain, M. Heiginbothom, F. Gannon, T. Smith, C. O’Sullivan, R. Hone, D. A. Caugant, C. A. P. Fijen, E. J. Van Schalkwyk, G. J. Coetzee, U. Ni Riain, M. G. Cormican, L. Park, J. Flynn, V. Regazzoli, M. Hayes, G. Nicholson, P. Higgins, N. Flynn, G. Corbett-Feeney, D. J. Conway, N. J. O’Higgins, S. Rajendiran, J. Byrne, E. Kilfeather, P. Dingle, M. Hunter, S. K. Al-Ghazal, P. Stanley, J. Palmer, A. Hong, P. Saxby, D. Sheehan, I. Regan, J. O’Mullane, M. Ni Chaoimh, M. Leahy, J. J. Heffron, M. Lehane, C. Keohane, N. O’Leary, M. Sheehan, E. Renny-Walsh, M. J. Whelton, C. T. Doyle, J. Webster, N. Benjamin, S. FitzGerald, J. S. Chadha, M. G. FitzGerald, G. R. FitzGerald, L. Hemeryck, P. McGettigan, J. Golden, N. Arthur, S. Y. Wen, P. Deegan, T. Cooke, G. I. Adebayo, P. Gaffney, M. Sinnot, D. O’Riordan, T. Hayes, C. M. O’Connor, M. X. FitzGerald, C. Costello, G. Finlay, J. Hayes, C. O’Connor, K. McMahon, S. Hone, J. Robertson, R. Coakley, S. O’Neill, M. Walsh, J. McCarthy, D. Lannon, A. E. Wood, R. Sharkey, E. Mulloy, M. Long, I. Kilgallen, V. Tormey, S. Horne, T. Feeney, Ó. Ó Muiré, M. J. Griffin, D. Hughes, A. Knaggs, D. Magee, C. McCrory, B. March, D. Phelan, M. White, J. Fabry, D. Buggy, C. Cooney, E. Aziz, D. O’Keefe, A. J. McShane, J. Boylan, E. Tobin, C. Motherway, F. Colreavy, N. Denish, R. Dwyer, A. Bergin, K. O’Brien, R. MacSullivan, K. D. Carson, W. P. Blunnie, D. C. Moriarty, B. Kinirons, B. Lyons, N. Cregg, W. Casey, K. P. Moore, S. A. Colbert, C. Ecoffey, D. O’Gorman, J. Fitzgerald, P. Diamond, M. B. Codd, D. D. Sugrue, J. Kellett, M. Tighe, C. J. McKenna, J. Galvin, H. A. McCann, A. Scallon, A. Fraser, M. Norton, G. Tomkin, I. Graham, A. Byrne, M. Maher, N. Moran, D. Fitzgerald, D. O’Callaghan, D. Coyle, A. G. Nugent, C. McGurk, G. D. Johnston, A. Nugent, B. Silke, N. Murphy, L. Jennings, D. Pratico, C. Doyle, T. Hennessy, H. McCann, D. Sugrue, S. Donnelly, A. Hennessy, C. Hartigan, D. MacDonald, S. Blake, D. McDonald, D. Dominque, S. R. McMechan, G. MacKenzie, J. Allen, G. T. Wright, G. J. Dempsey, M. Crawley, J. Anderson, A. A. J. Adgey, M. T. Harbinson, N. P. S. Campbell, C. M. Wilson, P. K. Ellis, E. M. McIlrath, A. McShane, T. V. Keaveny, K. Rabenstein, F. Scheller, D. Pfeiffer, C. Urban, I. Moser, G. Jobst, A. Manz, S. Verpoorte, F. Dempsey, D. Diamond, M. Smyth, E. Dempsey, V. Hamilton, J. Twomey, R. Crowley, L. Fenelon, F. Walsh, J. McCann, P. McDonagh, E. McGovern, D. Luke, K. Crowley, D. Mannion, D. Murphy, K. Clarkson, E. Carton, I. Leonard, D. O’Toole, M. Staunton, M. Griffin, D. Owens, P. Collins, A. Johnson, G. H. Tomkin, N. A. Herity, J. D. Allen, R. O’Moore, G. M. Crotty, M. DeArce, K. Nikookam, P. Keenan, D. Cregan, N. O’Meara, S. Forman, D. A. Cusack, and B. Farrell
Subjects: medicine.medical_specialty, business.industry, Family medicine, medicine, MEDLINE, General Medicine, business
Published: 1995
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10. Dietary iodine intake in pregnancy: an update

Author: P, Smyth and C, O'Herlihy
Subjects: Pregnancy Complications, Pregnancy, Risk Factors, Developmental Disabilities, Humans, Female, Sodium Chloride, Dietary, Ireland, United Kingdom, Iodine
Published: 2012

11. Comparison of the motor discharge to the voluntary sphincters of continence in the rat

Author: M, Buffini, K D, O'Halloran, C, O'Herlihy, P R, O'Connell, and J F X, Jones
Subjects: Motor Neurons, Urethra, Electromyography, Urinary Bladder, Action Potentials, Anal Canal, Animals, Female, Rats, Wistar, Muscle, Skeletal, Rats
Abstract: The rat external anal sphincter (EAS) and external urethral sphincter (EUS) are voluntary muscles of continence that can display similar synchronous electromyographic (EMG) activity patterns. However, the two sphincters are quite different in structure and function. The EUS is a fast twitch muscle and contains fibers expressing type 2B myosin. In contrast, the EAS exhibits slower kinetics and lacks type 2B fibers. This striking contrast in kinetics and fiber type profiles may be shaped by differences in the basal motor drive that each sphincter receives. A double EMG approach was used to obtain spontaneously active single motor unit action potentials from the EUS and EAS simultaneously and compare their basal discharge frequencies in urethane anaesthetized rats. The basal firing rates of motor units of the EUS and EAS were not significantly different (3.9 ± 0.9 Hz vs. 3.1 ± 1.6 Hz, respectively, n = 7 animals, P = 0.32, paired Student's t-test). However, auto-correlogram analysis showed that EUS is driven by neurons with faster instantaneous firing frequencies: 30.5 ± 2.4 Hz vs 14.3 ± 0.9 Hz in the EAS (P = 0.03, paired Student's t-test). The oscillator(s) driving the EUS operate(s) at a frequency twice that of the EAS. This may explain the presence of type 2B fibers in the EUS. In the inter-micturition periods no cross correlation was found in motor discharge to the sphincters suggesting that the two muscles do not share a common central drive to sustain the continent tonus of the two outlet tracts.
Published: 2012

12. Irish endocrine society

Author: E. Dimitriadis, D. Owens, P. Collins, A. Johnson, G. Tomkin, C. C. Cronin, D. Barry, B. Crowley, J. B. Ferriss, A. M. Hetherton, D. F. Smith, C. O’Herlihy, P. P. A. Smyth, T. M. Fiad, M. Culliton, J. Dunbar, S. K. Cunningham, T. J. McKenna, A. P. Heaney, G. L. Loughrey, D. R. McCance, E. Mcllrath, D. R. Hadden, L. Kennedy, B. Sheridan, J. B. Ferris, A. Whyte, P. E. Cleary, D. J. McAuley, B. Mathew, I. C. Bailey, A. Curtin, K. Lenehan, P. Deegan, M. Henry, M. Stapleton, H. Baker, P. F. Duggan, T. H. Mitchell, J. A. O’Hare, M. Geoghegan, F. Abuaisha, U. Fearon, D. Clarke, R. N. Roberts, A. I. Traub, W. Thompson, H. Whitehead, J. Holmes, R. Roberts, N. A. Al-Mandhari, A. Greer, D. Carson, T. Traub, D. Hadden, T. Ferguson, A. B. Atkinson, S. O’Keeffe, J. G. Devlin, C. Donnellan, C. R. Russell, T. L. Kennedy, A. L. Kennedy, H. A. Long, D. J. Conway, P. M. Mercer, D. Murphy, M. Stokes, K. Sheahan, N. J. O’Higgins, F. P. Dunne, W. A. Ratcliffe, P. Mansour, D. A. Heath, N. M. O’Meara, J. Sturis, K. C. Herold, K. S. Polonsky, O. L. Beatty, C. M. Ritchie, P. M. Bell, J. C. Levy, E. Turkington, D. W. Hadden, R. Harper, C. N. Ennis, G. D. Johnston, P. Scanlan, M. Foley, J. Stronge, R. Firth, R. L. Hanson, L. T. H. Jacobsson, P. H. Bennett, D. T. Bishop, and W. C. Knowler
Subjects: medicine.medical_specialty, business.industry, Library science, General Medicine, Cork, engineering.material, language.human_language, Regional hospital, Irish, Ophthalmology, engineering, language, medicine, business
Published: 1994
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13. Is placental iodine content related to dietary iodine intake?

Author: R, Burns, F, Azizi, M, Hedayati, P, Mirmiran, C, O'Herlihy, and P P A, Smyth
Subjects: Dose-Response Relationship, Drug, Pregnancy, Placenta, Dietary Supplements, Humans, Biological Transport, Female, Iran, Ireland, Iodine
Abstract: Delivery of iodine to the foetus depends not only on maternal dietary iodine intake but also on the presence of a functioning placental transport system. A role for the placenta as an iodine storage organ has been suggested, and this study compares the iodine content of placentas from women giving birth at term in Ireland and Iran, areas with median urinary iodine of 79 and 206 μg/l respectively.Placental cotyledon iodine was measured using an alkaline ashing technique with Sandell-Kolthoff kinetic colorimetry. Samples were taken from six sites from the centre and periphery of each cotyledon. Placentas (Ireland n = 58; Iran n = 45) were obtained from consecutive euthyroid women delivering at term.The median placental iodine (μg/g wet weight) was significantly higher in Iranian than in Irish women (187·2 μg/g vs 34·3 μg/g; P0·001). The distribution of individual placental iodine values showed that values50μg/g were found in 71·0% of Iranian and in only 21·0% of Irish samples. In Irish subjects, the relationship of placental iodine to pregnant population urinary iodine (UI) (ng/g:μg/l) was 1:2 (40:79), while in Iranians this ratio is closer to 1:1 (211:206).These findings, by demonstrating an apparent ability of the placenta to store iodine in a concentration-dependent manner, suggest a hitherto undetected role for the placenta. Whether placental iodine has a role in protecting the foetus from inadequacies in maternal dietary iodine intake is as yet unknown.
Published: 2011

14. Ethnic variation between white European women in labour outcomes in a setting in which the management of labour is standardised-a healthy migrant effect?

Author: J, Walsh, R, Mahony, F, Armstrong, G, Ryan, C, O'Herlihy, and M, Foley
Subjects: Adult, Transients and Migrants, Labor, Obstetric, Cesarean Section, Pregnancy Outcome, Prenatal Care, Oxytocin, Obstetric Labor Complications, Analgesia, Epidural, Pregnancy, Oxytocics, Analgesia, Obstetrical, Birth Weight, Humans, Female, Europe, Eastern, Labor, Induced, Ireland, Retrospective Studies
Abstract: To test the hypothesis that women from Eastern European countries have lower caesarean delivery rates and higher spontaneous labour rates relative to Irish women in a setting in which the management of labour is standardised.A retrospective review of prospectively collected data.Tertiary referral centre, Dublin, Ireland.All Irish and Eastern European term nulliparous women who laboured and delivered in 2008.A comparison of labour outcomes between women from Ireland and women from Eastern European countries.The principal outcomes measured were the gestational age at onset of labour, whether labour was spontaneous or induced, the need for oxytocin augmentation, duration of labour, mode of delivery, epidural use and birthweight.Of 2556 Irish (n = 2041) and Eastern European (n = 511) term cephalic singleton labours in the calendar year 2008, women from Eastern Europe were significantly more likely to labour spontaneously (74.6% versus 65.9%, P0.001), required less epidural analgesia (68.4% versus 59.7%) and were significantly less likely to require delivery by caesarean section (8.6% versus 15.7%, P0.001) than Irish women. This is despite no significant difference between the two groups with regard to mean birthweight (3581 g versus 3569 g, P = 0.6) or macrosomia (birthweight over 4000 g) (18% versus 16%, P = 0.4). There were significant differences in maternal age at delivery (27.2 years versus 29.2 years, P0.001) and body mass index (BMI) (24.1 kg/m² versus 25.4 kg/m², P0.001) between the two groups.These findings confirm our hypothesis that economic migrants from Eastern European countries exhibit a so-called 'healthy migrant effect' in terms of obstetric outcomes.
Published: 2011

15. Irish endocrine society

Author: A. Bowie, D. Owens, P. Collins, A. Johnson, G. H. Tomkin, M. Barakat, D. Carson, A. M. Hetherton, P. Smyth, H. Leslie, H. A. Long, C. O’Herlihy, P. P. A. Smyth, J. Kirby, T. M. Fiad, S. K. Cunningham, T. J. McKenna, J. G. Devlin, E. Brosnan, O. L. Beatty, R. Harper, B. Sheridan, A. B. Atkinson, P. M. Bell, J. A. O’Hare, F. Abuaisha, M. Geoghegan, G. M. Brennan, J. P. Donnelly, L. T. McGrath, G. E. McVeigh, G. D. Johnston, J. R. Hayes, T. O’Brien, T. T. Nguyen, B. A. Kottke, R. Drury, D. Powell, S. Dundon, H. Hoey, D. Gill, R. G. H. Firth, M. Humphreys, C. C. Cronin, D. G. Barry, J. B. Ferriss, R. Freaney, Y. NcBrinn, M. J. McKenna, F. P. Dunne, S. Lee, W. A. Ratcliffe, D. A. Heath, C. M. Gleeson, W. J. Curry, C. F. Johnston, K. D. Buchanan, S. J. Hunter, M. E. Callender, W. H. Daughaday, J. A. McKnight, E. M. Mcllrath, J. D. Teale, F. Hayes, A. O’Brien, C. O’Brien, M. X. Fitzgerald, R. Jones, P. B. Collins, A. H. Johnson, N. M. O’Meara, J. D. Blackman, D. A. Ehrmann, R. L. Rosenfield, K. S. Polonsky, M. Culliton, and J. Dunbar
Subjects: Irish, business.industry, language, Library science, Endocrine system, Medicine, General Medicine, business, language.human_language
Published: 1993
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16. Recent trends in the caesarean section rate 1999-2006

Author: C, O'Herlihy, M E, Foley, and M, Robson
Subjects: Cesarean Section, Pregnancy, Humans, Female, Practice Patterns, Physicians', Ireland, Maternal Age
Published: 2010

17. Appropriate antenatal corticosteroid use in women at risk for preterm birth before 34 weeks of gestation

Author: R, Mahony, A, McKeating, T, Murphy, F, McAuliffe, C, O'Herlihy, and M, Foley
Subjects: Fetal Membranes, Premature Rupture, Adrenal Cortex Hormones, Pregnancy, Risk Factors, Pregnancy Complications, Cardiovascular, Humans, Premature Birth, Female, Hemorrhage, Prenatal Care, Prospective Studies, Ireland
Abstract: To determine the utilisation of antenatal corticosteroid administration in women presenting at risk of preterm birth (PTB) in a centre where tocolytics are not prescribed.A prospective cohort study.Tertiary referral centre, Dublin, Ireland.Four hundred and fourteen consecutive women presenting at risk of PTB.Clinical details were collated prospectively on all booked patients who presented at risk of PTB (i.e. at34 weeks of gestation) during 2008.Rate of administration of antenatal corticosteroids in PTB.Of 8985 deliveries, 414 women (5%) presented at34 weeks of gestation with a clinical potential for PTB, of whom 277 (67%) received antenatal corticosteroids. Amongst women delivering at34 weeks of gestation, 93% (80/86) received any corticosteroids and 76% (65/86) received a complete course. The ratio of women given a complete course of corticosteroids to the number who actually delivered before 34 weeks of gestation was 4:1 overall. Analysis by indication for PTB revealed this ratio to be 15:1 in suspected preterm labour (PTL), 8:1 in antepartum haemorrhage (APH), and 2:1 in both preterm prelabour rupture of membranes (PPROM) and medically indicated PTB (MIPTB). Seven of ten multiparae (70%) who delivered prematurely during the study period following PTL had a history of previous PTL before 34 weeks of gestation.The ratio of maternal antenatal corticosteroid administration for potential versus actual PTB at34 weeks of gestation was high in categories such as PTL and substantial APH, whereas selection in PPROM and MIPTB approached 100%. There should be a low threshold for single course therapy for women with prior PTL before 34 weeks of gestation.
Published: 2010

18. Irish perinatal society

Author: M. Zbaeda, E. Egan, B. G. Loftus, P. Cairns, J. Jenkins, D. C. Wilson, T. Baird, C. M. Scrimgeour, G. McClure, H. L. Halliday, M. Reid, M. J. Rennie, J. C. Dornan, P. Fogarty, J. Dornan, P. G. Hepper, S. Shahidullah, A. Halligan, M. Connolly, R. P. Gleeson, M. Holohan, T. Clarke, T. Matthews, M. King, M. R. N. Darling, S. F. Daly, A. S. Pooley, M. Philbin, M. McCreery, E. W. Lillie, B. M. Byrne, D. Keane, P. Boylan, J. M. Stronge, M. Pillai, D. James, M. Parker, P. O’Dwyer, B. O’Neill, R. Gleeson, J. E. Gillan, P. Crowley, D. Elbourne, H. Ashurst, J. Garcia, D. Murphy, N. Duignan, G. Burke, V. Donnelly, C. O'Herlihy, W. Gorman, S. M. Gormally, T. G. Matthews, D. Condell, R. Campbell, M. D. O’Hara, H. McNamara, N. Johnson, R. Lilford, T. G. Teoh, K. Hickey, A. C. Magee, F. J. Priest, N. C. Nevin, F. J. Stewart, J. Nevin, M. J. Armstrong, K. Robinson, B. Stuart, I. Graham, and H. Refsum
Subjects: Pediatrics, medicine.medical_specialty, Irish, business.industry, language, Medicine, General Medicine, Ancient history, business, language.human_language
Published: 1992
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19. Increased maternal age protects against striae gravidarum

Author: B. Dunphy, K. W. Murphy, and C. O'herlihy
Subjects: medicine.medical_specialty, Pediatrics, business.industry, Obstetrics, Birth weight, Incidence (epidemiology), Obstetrics and Gynecology, Stepwise regression, medicine.disease, eye diseases, Relative risk, Striae gravidarum, Medicine, business, Body mass index
Abstract: SummaryThe relationship between clinical data and the subsequent occurrence of striae gravidarum was studied in a consecutive series of 261 primiparae, using a stepwise logistic regression analysis. The incidence of striae was 42-9 per cent. Variables which demonstrated an independent relationship with the occurrence of striae were maternal age (P
Published: 1992
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20. Cerebral palsy following neonatal hypoxic seizures in singleton term infants: the influence of parity

Author: R, Mahony, F, Enright, C, O'Herlihy, and M E, Foley
Subjects: Male, Parity, Pregnancy, Risk Factors, Seizures, Cerebral Palsy, Incidence, Infant, Newborn, Humans, Female, Hypoxia, Brain, Ireland, Retrospective Studies
Abstract: This was a retrospective review of term singleton neonates (37 weeks) with early onset seizures, with and without encephalopathy, from 1989 through 2000. Our aim was to examine the relationship between antepartum and intrapartum obstetric events, neonatal hypoxic seizures and subsequent neurological impairment of 77,838 infants, the incidence of seizures was significantly higher among primiparas (2.4/1000; 67/31,729) compared with multiparas (0.35/1000; 16/46,109)(p0.001). Compared with multiparas, seizures with encephalopathy occurred more frequently among primiparas (0.8/1000; 26/31,729) vs. multiparas (0.2/1000; 8/46,109), were more commonly associated with unexplained intrapartum hypoxia (0.6/1000, n = 20 vs.0.04/ 1000, n = 2) and the incidence of cerebral palsy, 45% (9/20) vs. 0% (0/2) was significantly higher(p0.001). Seizures with encephalopathy (0.2/1000 vs.0.13/1000) and cerebral palsy (33%) had a similar incidence in primiparas and multiparas following a sentinel event. Neonatal seizures with encephalopathy, related to intrapartum events, were 4 times more common following first delivery and associated with a 9 fold higher incidence of cerebral palsy, implicating primiparous labor in the development of cerebral palsy.
Published: 2009

21. Correlation of perineal outcome at first and second vaginal deliveries

Author: R, Mahony, C, O'Herlihy, and M E, Foley
Subjects: Episiotomy, Pregnancy, Risk Factors, Incidence, Humans, Female, Perineum, Vaginal Birth after Cesarean
Abstract: Perineal outcome in 1000 consecutive term non instrumental second vaginal deliveries was correlated with first delivery method and perineal outcome. Our aim was to determine the relationship between perineal outcome at first and second vaginal deliveries. Overall 75% of first non instrumental vaginal deliveries required sutures. Sutures were required at second delivery in 12% (24 of 199) of cases not sutured at first delivery compared with 60.4% (485 of 801) of those sutured. The rate of second perineal repair correlated with method of first delivery and perineal outcome, instrumental delivery--66.2% (145 of 219), first episiotomy-68.4% (238 of 348) and first sutured tear--43.6% (102 of 234). The incidence of third /fourth degree tear at first delivery was 1.3% (13/1000) (one recurred at second forceps delivery), compared with 0.6% at second delivery. First delivery outcome should be considered when conducting a second delivery as sixty per cent of women require perineal repair following repair at first delivery.
Published: 2009

22. Anal canal pressures are low in women with postpartum anal fissure

Author: H. Corby, V. S. Donnelly, C. O'herlihy, and P. R. O'connell
Subjects: Surgery
Published: 1997
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23. Anal canal pressures are low in women with postpartum anal fissure

Author: C. O'herlihy, H. Corby, V. S. Donnelly, and P. R. O'Connell
Subjects: medicine.medical_specialty, Anal fissure, Pregnancy, Pelvic floor, Constipation, Fissure, business.industry, Anal canal, medicine.disease, Surgery, medicine.anatomical_structure, medicine, Childbirth, medicine.symptom, Prospective cohort study, business
Abstract: Background Anal sphincter hypertonia is commonly thought to underlie development of anal fissure, yet anal fissure is particularly common after childbirth, a time when anal canal pressure may be reduced. This paradox was investigated by a prospective study of the effect of parturition on the pelvic floor. Methods Anal manometry was performed 6 weeks before and after delivery in 209 primigravid women with no pre-existing history of anorectal disease. Postpartum studies only were performed on a further 104 primiparae. Anal fissure was diagnosed by history and direct examination. Results Some 29 women (9 per cent) developed postpartum anal fissure. Antepartum anal canal resting and squeeze pressures were similar in women who did and those who did not develop fissure. Resting and squeeze anal canal pressures decreased post partum in both groups. Postpartum constipation was more common in those with fissure (62 per cent) than in those without (29 per cent) ( X 2 = 10.6, 1 d.f., P
Published: 1997
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24. Elective Caesarean section is associated with a reduction in developmental dysplasia of the hip in term breech infants

Author: C. A. Lowry, V. B. Donoghue, C. O’Herlihy, and J. F. A. Murphy
Subjects: Joint Instability, medicine.medical_specialty, medicine.medical_treatment, Breech presentation, Pregnancy, Epidemiology, Medicine, Humans, Orthopedics and Sports Medicine, Caesarean section, Breech Presentation, reproductive and urinary physiology, Bone Diseases, Developmental, business.industry, Vaginal delivery, Obstetrics, Cesarean Section, Incidence (epidemiology), Infant, Newborn, medicine.disease, female genital diseases and pregnancy complications, medicine.anatomical_structure, Dysplasia, Orthopedic surgery, Vagina, Surgery, Female, Hip Joint, business
Abstract: We wished to establish whether delivery by Caesarean section influenced the incidence of developmental dysplasia of the hip in term breech infants compared with those delivered vaginally. We used maternal charts, singleton term breech presentation, mode of delivery and incidence of developmental dysplasia of the hip for births between January 1997 and October 2002. During the study period 46 089 infants were born. We analysed a total of 941 breech infants of whom 756 were delivered by Caesarean section (515 pre-labour, 241 intrapartum) and 185 vaginally. The incidence of developmental dysplasia of the hip according to the mode of delivery was 19 of 515 (3.69%) following pre-labour Caesarean section, 16 of 241 (6.64%) for intrapartum Caesarean section and 15 of 185 (8.11%) after vaginal delivery. There was a lower incidence of developmental dysplasia of the hip among those infants delivered by elective Caesarean section compared with those delivered vaginally (p < 0.02). These results demonstrate a significantly lower incidence of developmental dysplasia of the hip in term singleton breech births delivered by elective, pre-labour Caesarean section and suggest that labour and delivery influence hip stability in predisposed infants.
Published: 2005

25. The effects of labour and delivery on the pelvic floor

Author: C O'Herlihy and M Fitzpatrick
Subjects: medicine.medical_specialty, Stress incontinence, Manometry, Pudendal nerve, medicine.medical_treatment, Urinary Incontinence, Stress, Anal Canal, Urinary incontinence, Pelvis, Pregnancy, Endoanal ultrasound, medicine, Childbirth, Humans, Caesarean section, Muscle, Skeletal, Physical Therapy Modalities, Ultrasonography, Pelvic floor, business.industry, Obstetrics, Electromyography, Obstetrics and Gynecology, General Medicine, Pelvic Floor, medicine.disease, Magnetic Resonance Imaging, Surgery, Perineum, Diet, Obstetric Labor Complications, medicine.anatomical_structure, Female, medicine.symptom, business, Fecal Incontinence
Abstract: Increasing public and professional attention has recently been focused on the issue of both faecal and urinary incontinence following childbirth and these symptoms are sometimes being cited as indications for elective caesarean section. Faecal incontinence has a female-to-male preponderance of 8:1, consistent with childbirth as the principal causative factor, although most symptomatic women do not seek medical advice until after the menopause. Similarly, urinary stress incontinence is almost an exclusively female phenomenon. Obstetric injury may take the form of direct muscular damage to the anal sphincter, as occurs during a third-degree tear, and/or may be the result of cumulative damage to the pudendal nerves. Mechanical, neural and endocrine factors may all play a causative role in faecal incontinence. Symptoms are rarely volunteered by the patient, and may be present for many years after the index pregnancy, and clinical examination alone may fail to detect specific abnormalities. The performance of anal manometry, endoanal ultrasound, urodynamics and neurophysiology studies of the pelvic floor may help to increase the diagnostic yield. Treatment for both urinary and faecal incontinence is available in the form of physiotherapy, fluid and dietary manipulation and in more severe cases, surgery. Adequate primary management of third-degree tears requires careful appraisal as this injury, in particular, is the most important risk factor for subsequent faecal incontinence symptoms. In this chapter we aim to outline the mechanism of damage to the pelvic floor during childbirth, concentrating primarily on anal sphincter damage. We describe the necessary investigations, follow-up and treatment which women with significant pelvic floor damage should receive following delivery, and we finally discuss the issue of further deliveries and, specifically, the current place of caesarean section.
Published: 2001

26. Selected abstracts

Author: P. P. Corkery, B. F. Leek, B. Caulfield, M. Garrett, J. P. Gormley, P. M. O’Donnell, N. Kennedy, K. Sayers, E. Stokes, B. Bresnihan, O. Fitzgerald, M. A. McGarvey, M. Tonra, A. C. B. Hooper, J. Barry, B. Maurer, J. Hussey, J. Gormley, J. G. Noble, J. Alves-Guerreiro, A. S. Lowe, D. M. Walsh, B. NicNiocaill, M. Harte, W. T. O’Connor, A. M. O’Hara, A. Orren, A. P. Moran, D. A. Hardiman, T. C. Lee, D. T. Croke, R. Tolan, S. McBennett, S. Warmington, M. McGuire, A. Bradford, T. O’Hare, M. MacDermott, F. Lynch, R. G. O’Regan, P. McLoughlin, T. Quinn, J. P. Ryan, M. Pickering, D. P. Campion, J. F. X. Jones, S. Ryan, W. T. McNicholas, P. Nolan, F. J. Doyle, S. M. Rackard, P. Beddy, V. A. Campbell, Y. S. Bakhle, C. Bell, C. Usher, L. Chan, A. K. Keenan, K. E. McQuaid, V. C. Cullen, E. M. Smith, A. Kelly, M. A. Lynch, D. B. Freir, C. Holscher, C. E. Herron, H. A. Pearson, B. P. Curran, J. J. O’Connor, A. Quinn, J. McHale, D. Moriarty, J. O’Connor, J. C. Glennon, B. J. Van Vliet, S. K. Long, C. Kruse, H. C. Gallagher, C. L. Bacon, B. Boland, A. M. Griffin, J. Preisler, L. O’Brien, C. M. Regan, S. Hurley, P. J. Kearney, J. Slevin, C. Barry-Kinsella, C. A. Ryan, O. Kllleen, J. Glllan, T. Clarke, T. Matthews, D. Corcoran, E. Dunn, M. Geary, C. O’Herlihy, D. Keane, M. M. Slattery, M. J. O’Leary, J. J. Morrison, E. Ryan, W. A. Gorman, A. Bourke, J. Larkin, C. Mayes, J. Jenkins, M. Ryan, S. Lalchandani, O. Sheil, N. Lynch, C. Costigan, J. F. Murphy, R. Bhatia, A. Foran, V. Donohue, P. McParland, P. LaSjaunais, G. Rodesch, M. McGinn, J. McAloon, M. O’Leary, K. Astbury, D. Harmon, A. Sharkey, G. Gaffney, G. O’Regan, C. McMahon, D. Murray, C. McDermott, E. Woolhead, J. Gillan, J. L. Cartmill, M. A. Harper, N. Al-Shabibi, M. Hanahoe, M. Wingfield, J. A. M. Larkin, A. H. Bell, B. G. McClure, L. Sweeney, D. H. Martin, P. O’Donoghue, A. Davoren, G. F. Lucas, J. McKiernan, D. M. T. Gallagher, K. P. Dunne, O. Fulena, M. Sheridan, E. Griffin, M. White, P. Deasy, M. O’Riordan, C. O’Gorman, C. Mongan, M. McCafferkey, G. Henry, P. McKenna, A. O’Malley, D. Devaney, P. Kelleghan, E. E. Mooney, J. E. Gillan, M. Fitzpatrick, K. McQuillan, C. Heffron, P. Hodnett, A. Curtain, T. C. F. O’Connor, T. G. Connell, D. Waldron, W. Gorman, T. Bolger, M. O’Keefe, J. Murphy, L. M. Dolan, A. I. Traub, A. E. Curley, H. L. Halliday, T. R. J. Tubman, O. Kileen, H. Riadha, J. Russell, R. Philips, C. Regan, I. Ali, A. C. J. Coughlan, M. J. Turner, A. Smith, D. O’Flanagan, D. Igoe, F. Ryan, D. Forde, E. McArdle, D. Ko, D. Bedford, M. Hegarty, B. Dunlevy, R. Corcoran, T. Holohan, A. Feeney, H. McGee, W. Shannon, M. Condon, C. Hyland, G. Sayers, E. Feely, D. Crowley, D. O’Reilly, T. O’Connell, M. Cronin, H. Johnson, M. Fitzgeraldi, M. Cafferkey, A. Breslin, C. J. Bonner, B. Foley, M. Fitzgerald, P. G. Wall, E. McNamara, P. Costigan, T. Prendergast, K. Foye, C. Cosgrove, A. Keane, E. Murphy, J. O’Donnell, A. Quinlan, L. Thornton, E. A. Roch, R. A. Lyons, A. Maddocks, P. Barnes, L. Price, M. McCabe, P. Nash, A. Midha, Y. Doyle, A. Kilgallen, P. Wright, T. Ryan, D. De La Harpe, V. Harkins, C. Brennan, V. O’Connell, D. S. Evans, J. Ni Mhuircheartaigh, J. M. O’Donnell, A. Rhatigan, E. Shelley, C. Collins, M. Byrne, A. W. Murphy, P. K. Plunkett, A. Murray, G. Bury, F. Lynam, G. McMahon, T. Greally, D. Kane, D. Veale, R. Reece, S. Busteed, M. W. Bennett, M. Stone, C. Molloy, J. O’Connell, M. G. Molloy, F. Shanahan, J. Guerin, E. Casey, C. Feighery, F. Lin, J. Jackson, A. Pendleton, G. D. Wright, A. E. Hughes, D. O’Gradaigh, I. Debham, J. Compston, A. McEvoy, E. P. Murphy, D. Salonen, P. Payne, M. Lax, V. Lapp, R. Inman, K. O’Rourke, D. Brennan, J. Harty, C. McCarthy, J. O’Byrne, S. Eustace, H. Chirayath, N. W. Liggett, M. P. Morgan, D. J. Fitzgerald, C. J. McCarthy, G. M. McCarthy, R. Z. Lee, K. Wai, D. Nevin, A. O. Leary, R. Lee, E. B. Casey, A. O’Leary, D. Breen, D. Tuite, D. McInerney, R. Sim, A. L. Frederic, O. Smith, B. White, M. Murphy, C. Silke, E. O’Keeffe, N. Fanning, L. Spence, N. A. Parfrey, J. R. McConnell, A. D. Crockard, A. P. Cairns, A. L. Bell, O. Kavanagh, D. A. Moyes, M. Finch, M. Rooney, A. Bell, I. Founas, A. El-Magbri, S. Mooney, M. Kennedy, R. J. Coughlan, S. A. Ramakrishnan, A. Gsel, O. Finnerty, M. Burns, M. Yateman, C. Camaco-Hubner, C. F. Matthews, A. Taggart, K. Fuller, M. S. Murphy, M. Phelan, T. B. Murphy, F. Wynne, K. Quane, M. Daly, J. O’Leary, I. da Silva, N. Bermingham, M. Gogarty, L. P. Gallagher, R. O’Hara, C. Godson, H. Brady, H. Osman, A. El-Rafie, D. Foley-Nolan, P. Kirwan, O. Corcoran, T. Duffy, F. Drummond, A. Madigan, D. Williams, P. Gallagher, C. Hatton, S. Cunningham, O. FitzGerald, P. Minnock, E. Wylie, D. Egan, J. Mc Cormack, M. O. Shea, D. Evans, P. O’Lorcain, H. Comber, A. Evans, J. Jones, C. Garavan, K. Kelleher, M. C. Boland, R. Healy, M. B. O’Sullivan, M. Burke, P. Mc Donald, R. Smithson, J. Glass, C. A. Mason, N. Mullins, D. Nolan, P. McCormick, S. Coughlan, S. Dooley, C. C. Kelleher, A. Hope, F. Murphy, M. Barry, J. Sixsmith, A. MacFarlane, C. MacLeod, G. McElroy, D. O’Loan, F. Kennedy, R. M. Kerr, J. Lim, S. P. A. Allwright, F. L. Bradley, J. M. G. Barry, J. Long, J. V. Parry, D. Creagh, I. J. Perry, A. Collins, S. Neilson, N. Colwell, D. O’Halloran, S. O’Neill, S. McErlain, M. Okasha, B. Gaffney, P. McCarron, R. Hinchion, C. Drew, A. Gavin, D. Fitzpatrick, R. Campbell, S. G. Wannamethee, A. Shaper, S. Friel, C. Kelleher, F. Kee, C. C. Atterson, E. A. Wilson, J. M. McConnell, S. M. Wheeler, J. D. Watson, N. Norashikin Rahman, J. Sheehan, C. Wall, B. Kelleher, S. D. O’Broin, R. N. Mullan, P. J. McKeveney, V. M. Hodges, P. C. Winter, P. Maxwell, D. A. Simpson, T. R. J. Lappin, A. P. Maxwell, J. A. Eustace, J. Coresh, C. Kutchey, P. L. Te, L. F. Gimenez, P. J. Scheel, M. Walser, R. A. McMahon, M. Clarkson, F. Martin, H. R. Brady, C. Blake, Y. M. O’Meara, S. Gupta, H. MacKenzie, S. Doyle, T. Fotheringham, P. Haslam, M. P. Logan, P. Conlon, M. Lee, P. Maderna, D. C. Cottell, S. Mitchell, C. Gulmann, R. Østerby, H. J. Bangstad, S. Rljdberg, M. Dempsey, S. Nathwani, M. P. Ryan, B. McMahon, C. Stenson, H. Murtagh, J. H. Brown, P. Doran, A. McGinty, M. A. Little, E. O’Brien, P. Owens, J. Holian, F. Mee, J. J. Walshe, S. A. Omer, D. Power, P. Diamond, R. W. Watson, A. Shahsafei, T. Jiang, B. M. Brenner, H. S. Mackenzie, J. Neary, A. Dorman, M. Keoghan, E. Campbell, J. Walshe, M. Little, L. Nee, C. O’Ceallaigh, H. McGlynn, E. Bergin, P. J. Garrett, T. Keane, G. Gormley, A. Watson, M. G. Atta, T. M. Perl, X. Song, E. Healy, M. Leonard, J. Lynch, A. J. Watson, D. Lappin, D. W. P. Lappin, K. Hannan, M. Burne, F. Daniels, H. Rabb, B. McBride, N. Kieran, C. Shortt, M. Codd, F. Murray, A. McCormack, C. Brown, C. Wong, A. M. Dorman, M. Keogan, J. Donohue, J. Farrell, J. Donohoe, S. O’Broin, A. Balfe, G. J. Mellotte, K. A. Abraham, C. McGorrian, A. E. Wood, M. Neligan, B. D. Kelly, P. Finnegan, M. Cormican, J. Callaghan, J. K. G. Crean, T. A. Moffitt, H. L. Devlin, A. Soosay, D. O’Neill, A. Counihan, D. Hickey, M. T. Keogan, K. Harvey, E. O’Riordan, S. Waldek, P. A. Kalra, D. J. O’Donoghue, R. N. Foley, A. O’Riordan, D. Kelliher, G. Mellotte, L. Giblin, J. A. B. Keogh, M. O’Connell, A. O’Meara, F. Breatnach, J. Gillick, H. Tazawa, P. Puri, E. Molloy, A. J. O’Neill, M. Sheridan-Pereira, J. M. Fitzpatrick, D. W. Webb, R. W. G. Watson, B. Linnane, C. O’Donnell, T. A. Clarke, C. Martin, M. McKay, J. McBrien, F. Glynn, C. O’Donovan, W. W. Hall, J. Smith, K. Khair, R. Liesner, I. M. Hann, O. P. Smith, S. Gallagher, M. J. Mahony, A. Hilal, J. F. Cosgrove, C. Monaghan, B. Craig, A. Al-Hassan, K. Walsh, D. Duff, P. O. Slizlok, C. Halahakoon, C. MacPherson, S. McMillan, E. E. Dalzell, J. McCaughan, A. O. B. Redmond, D. DeCaluwe, A. Yoneda, U. Akl, E. Dempsey, M. Farrell, D. Webb, A. Elabbas, G. Fox, S. Gormally, B. Grant, C. W. B. Corkey, A. Nicholson, A. Murphy, P. O’Grady, O. Barry, C. Macpherson, M. C. Stewart, F. Alderdice, T. G. Matthews, M. McDonnell, C. McGarvey, M. O’Regan, M. Ní Chróinín, P. Tormey, S. Ennis, A. J. Green, S. Abbas, A. O’Marcaigh, M. Conran, E. Crushell, A. Saidi, P. Curran, V. Donoghue, M. D. King, B. Elnazir, J. Leonard, C. Kavanagh, D. Brown, N. Corrigan, B. McCord, M. Quinn, L. O’Connell, B. Mcdonagh, A. Awan, D. Gill, R. Kakkar, D. G. Sweet, J. A. Warner, C. O’Connor, M. Herzig, A. Twomey, M. J. White, B. Sweeney, R. Surana, A. Hodgson, M. Rafferty, W. Livingstone, D. Peake, E. Wassemer, W. Whitehouse, N. Abdullah, P. Oslizlok, N. O’Connell, J. Balding, W. J. Livingstone, M. Healy, L. Mynett-Johnson, I. McAllister, A. C. Dick, B. Herron, V. E. Boston, C. O. Callaghan, D. O. Brien, A. Walsh, M. Philip, D. McShane, M. C. V. Hoey, F. Sharif, M. McDermott, M. Dillon, B. Drumm, M. Rowland, C. Imrie, S. Kelleher, B. Bourke, M. Iqbal, Y. Ziedan, M. O’Neill, S. O’Riordan, S. M. B. Basheer, S. O’Callaghan, A. Chong, M. Kelly, A. J. Nicholson, R. Cooke, C. Sreenan, M. Fallon, B. Denham, V. Dowding, G. Cussen, V. McManus, O. Hensey, H. Monaghan, S. N. Basheer, E. Quinn, H. M. C. V. Hoey, S. Mohamed, R. R. Ramesh, P. Mayne, E. Tracy, S. M. Gormally, E. Curtis, N. McCallion, R. Watson, O. O’Mahony, M. Keegan, K. Ward, D. Barton, J. Poulton, E. Treacy, J. Honour, D. deCaluwe, M. Ni Chróinín, J. Cosgrove, T. S. Chaudhry, N. M. Long, B. Lynch, P. Lasjaunais, D. G. M. McDonald, J. B. McMenamin, M. J. Farrell, E. F. Roche, A. Menon, C. Buckley, A. Mackey, K. Ohlandieck, A. Das, D. Reilly, O. Killeen, J. Harper, E. Roche, H. Hoey, J. Caird, D. O’Brien, D. Allcutt, N. Farrington, J. F. A. Murphy, J. M. Savage, A. J. Sands, F. A. Casey, B. G. Craig, J. C. Dornan, J. Johnston, C. Patterson, C. Lynch, H. C. Mulholland, D. C. Watkins, I. Young, G. Cran, C. A. G. Boreham, W. A. McCallion, N. F. Clements, M. R. Stevenson, D. O’Donoghue, L. Jenkins, A. J. Thompson, M. D. Shields, R. T. Taylor, R. Kerr, J. L. Hughes, M. Stewart, P. Jackson, C. Fitzpatrick, M. Rasheed, E. Colhoun, A. G. Bailie, S. Gray, S. Brown, A. Curley, K. J. MacMahon, C. M. O’Connor, A. Nichelson, N. E. Lynch, D. Finch, M. Foley, E. Scallan, B. Dillon, S. Lyons, R. O’Loughlin, M. Ward, R. Nally, A. Harkin, J. P. Kelly, B. E. Leonard, B. Nic Niocaill, P. Magee, T. J. Connor, Y. Shen, G. R. McCullough, S. M. McDonough, A. F. L. Cramp, M. Hynes, P. Corkery, M. Carey, D. McGarrigle, S. Higgins, H. Murray, C. J. Moran, M. C. Dennedy, J. Brosnan, L. Morris, B. L. Sheppard, A. Black, B. Wilkins, J. Folan-Curran, K. Skelton, M. Owens, C. Nemeroff, D. Houlihan, C. O’Keeffe, N. Nolan, P. A. McCormick, A. W. Baird, I. Raducan, P. Corcoran, R. Brennan, P. Molloy, A. Friel, M. Maher, M. Glennon, T. Smith, A. Nolan, J. A. Houghton, O. Carroll, S. Colleran, G. O’Cuinn, H. M. Snow, D. O’Regan, H. F. Markos, K. Pollock, D. M. Cannon, G. McBean, L. R. Quinlan, M. T. Kane, B. D. Higglns, D. M. Moriarty, D. Fitzgerald, A. Katkada, G. Canny, P. MacMathuna, M. M. O’Donovan, A. G. Schuur, K. J. Murphy, A. G. Foley, S. J. M. ten Bruggencate, and L. Ireland
Subjects: General Medicine
Published: 2000
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27. Prevalence of hysterectomy in Ireland

Author: S Ong, M Coughlan, Mary B. Codd, and C O'Herlihy
Subjects: Adult, medicine.medical_specialty, medicine.medical_treatment, Population, Hysterectomy, Cohort Studies, Age Distribution, Risk Factors, Surveys and Questionnaires, Epidemiology, medicine, Health insurance, Prevalence, Humans, education, Aged, Probability, Gynecology, education.field_of_study, High prevalence, Chi-Square Distribution, business.industry, Obstetrics and Gynecology, Gestational age, General Medicine, Middle Aged, Logistic Models, Socioeconomic Factors, Population Surveillance, Cohort, Female, Parity (mathematics), business, Ireland, Demography
Abstract: Objectives: To assess factors influencing the prevalence of hysterectomy in Ireland. Methods: Analysis of results of a questionnaire completed by a population-based cohort of 17 735 women aged 50–65 years attending for breast screening. Results: Prevalence of hysterectomy was 22.2%, was increased in proportion to parity and was higher in younger women, those who had previously used oral contraception and those who had private health insurance; peak age at operation was 45–49 years. Conclusion: The relatively high prevalence parity reflects contraceptive practices and utilization of health service resources.
Published: 2000

28. Menstrual cycle dependent fluctuations in NK and T-lymphocyte subsets from non-pregnant human endometrium

Author: L, Flynn, B, Byrne, J, Carton, P, Kelehan, C, O'Herlihy, and C, O'Farrelly
Subjects: Adult, Immunity, Cellular, Lymphokines, Receptors, Antigen, T-Cell, gamma-delta, Middle Aged, Flow Cytometry, Killer Cells, Natural, Endometrium, Antigens, CD, T-Lymphocyte Subsets, Immune Tolerance, Humans, Female, Embryo Implantation, Lymphocyte Count, Menstrual Cycle
Abstract: To establish the relative proportions of endometrial lymphocyte subpopulations during the menstrual cycle.Lymphocytes were investigated by flow cytometry, during the early proliferative (EP), late proliferative (LP), early secretory (ES) and late secretory (LS) phases of the menstrual cycle.Between the LP and LS phases, there was an increase in NK cells from 26.4% to 83.2% (P = 0.0017) of the CD45+ population. T cells decreased from 55.06% to 6.7% (P = 0.0017). Within the T-cell population, CD8+ cells decreased significantly from 63.0% in the LP phase to 54.2% in the LS phase (P = 0.04). In contrast, potential regulatory populations such as double negative (DN) T cells CD3+CD4-CD8- and natural T cells (NT) CD3+CD56+, increased significantly in the LS phase (P = 0.05; P = 0.03). gammadelta T cells, predominantly of the DN and NT phenotypes remained consistently low at all stages of the cycle (2.34%).Endometrial lymphocyte fluctuations during the menstrual cycle may reflect hormonal regulation of maternal immunity, thereby promoting tolerance at the time of implantation.
Published: 2000

29. Cesarean delivery and anal sphincter injury

Author: M, Fynes, V S, Donnelly, P R, O'Connell, and C, O'Herlihy
Subjects: Adult, Time Factors, Cesarean Section, Pregnancy, Anal Canal, Humans, Wounds and Injuries, Female, Prospective Studies, Labor Stage, Third
Abstract: Cesarean delivery has been thought to prevent all obstetric anal sphincter damage. The objective of this study was to determine the relationship between the timing of cesarean during primiparous delivery and injury to the anal sphincter mechanism.A prospective observational study was conducted, using a continence questionnaire and anorectal physiology assessment before and six weeks after primiparous delivery. A cohort of 234 women were recruited from the antenatal clinics at the National Maternity Hospital, Dublin. Thirty-four women delivered subsequently by cesarean, and 200 women by spontaneous vaginal delivery.Thirty-four women underwent cesarean delivery without attempted vaginal delivery: eight prior to labor and 26 during labor, 17 in early labor (cervical dilatation less than 8 cm) and 9 in late labor (dilatation greater than 8 cm). No woman delivered by cesarean had altered fecal continence postpartum. Anorectal physiology was unaltered in women delivered by elective cesarean or cesarean in early labor. Pudendal nerve terminal motor latency was prolonged, anal squeeze pressure increment reduced, but vector symmetry index was unchanged in women delivered by cesarean delivery late in labor, indicating neurologic injury to the anal sphincter mechanism.Cesarean delivery performed in late labor, even in the absence of attempted vaginal delivery, does not protect the anal sphincter mechanism.
Published: 1998

30. Discrimination by parity is a prerequisite for assessing obstetric outcome

Author: Michael Foley, M Robson, and C O'Herlihy
Subjects: Gynecology, medicine.medical_specialty, business.industry, medicine.medical_treatment, Obstetrics and Gynecology, Spontaneous labor, General Medicine, Induction of labor, Pediatrics, Perinatology and Child Health, medicine, Gestation, Computer database, Caesarean section, Parity (mathematics), business
Abstract: Background A PubMed search (2004-2011) yielded 115 abstracts on induction of labor of which 27(23.5%) specifically stated that the study was confined to nulliparas or multiparas, 23(20%) mentioned parity as a variable and 65 (56.5%) did not mention parity. The objective was to clarify the major differences between nulliparas and multiparas so that in future, labour outcomes would be reported separately for nulliparas and multiparas. Methods Obstetric data were collated on a computer database on all patients at the time of delivery for the year 2009. Results Among 9161 women (nulliparas, n=4407, multiparas, n=4754) there were 3882 nulliparas and 3563 multiparas (without scar) at term (> 37 weeks gestation). The caesarean section rate was significantly higher amongst nulliparas compared with multiparas for both spontaneous labor (195/2502; 7.8% vs. 25/2678; 0.9%) and induced labor (389/1311;29.7.%v.s.51/811; 6.3%, P Conclusion The results confirm the major differences between nulliparas and multiparas and provide unequivocal evidence that obstetric outcome should be reported separately by parity.
Published: 2012
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31. Patient-controlled analgesia using a miniature electrochemically driven infusion pump

Author: C. O'herlihy, D. O'keefe, Y. Gross, and J.G. Kelly
Subjects: Nursing staff, Morphine, Patient-controlled analgesia, business.industry, Cesarean Section, medicine.medical_treatment, Small systems, Micropump, Analgesia, Patient-Controlled, Equipment Design, Sensitivity and Specificity, Anesthesiology and Pain Medicine, Pregnancy, Anesthesia, medicine, Infusion pump, Analgesia, Obstetrical, Humans, Female, business, Infusion Pumps
Abstract: We describe a miniature electrochemically driven, wrist-worn infusion pump. Generation of gas by an electrolytic reaction compresses a reservoir containing medication and provides a predictable and controllable infusion rate. The pump was used for patient-controlled analgesia (PCA) in women who required analgesia after Caesarean section. It was accepted readily and was convenient for both patients and nursing staff. This portable system, using a novel motive force, has advantages of convenience over larger systems and has sophisticated features not present in existing small systems. It has potential as a routine PCA device and it may have uses in other situations requiring convenient infusion or intermittent injection in an ambulatory setting.
Published: 1994

32. Short-Term Changes in Maternal and Neonatal Urinary Iodine Excretion.

Author: P.P.A. Smyth, D.F. Smith, S. Sheehan, M. Higgins, R. Burns, and C. O'Herlihy
Subjects: IODINE, BLADDER, MOTHERS, BREASTFEEDING
Abstract: Investigation of maternal urinary iodine (UI) excretion in the immediate antenatal and early postpartum periods showed a precipitous fall in median values from 93 μg/L antenatally to 36 μg/L at delivery subsequently rising to 49 μg/L and 63 μg/L at days 3 and 10 postpartum respectively. The fate of ingested iodine not appearing in the maternal urine is unknown but measurement of UI in babies born to nursing mothers suggested transfer from the mother with median neonatal values of 117 and 159 μg/L being recorded at days 3 and 10. While maternal UI seemed to relatively unaffected by breast feeding, median UI from breast feeding babies (148 μg/L) was significantly greater than in those bottle feeding (50 μg/L). This was also reflected by the finding that no breast feeding baby had a UI values < 50 μg/L in comparison to 50% of bottle feeders. The depressed values in mothers and relatively high values in their infants could present a false picture and suggest the need to defer any investigations of iodine status at this time. The findings do however suggest a need for further investigations aimed at determining the fate of iodine ingested perinatally and its possible physiological significance in maintaining thyroid status in the mother and neonate. [ABSTRACT FROM AUTHOR]
Published: 2007
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33. MONITORING OVARIAN FOLLICULAR DEVELOPMENT WITH REAL-TIME ULTRASOUND

Author: H. P. Robinson, C. O'Herlihy, and L. J. Ch De Crespigny
Subjects: Ovulation, Gynecology, endocrine system, medicine.medical_specialty, business.industry, media_common.quotation_subject, Ultrasound, Single measurement, Obstetrics and Gynecology, Real time ultrasound, Ovarian cycle, Andrology, Follicle, Ovarian Follicle, Follicular phase, Humans, Medicine, Female, Obese subjects, business, Monitoring, Physiologic, Ultrasonography, media_common
Abstract: Summary Ovarian follicular growth during the periovulatory period was measured using real-time ultrasound in 33 patients during 53 spontaneous ovulatory cycles. The mean follicular diameter increased from 14·1 mm four days before ovulation to a maximum of 20·1 mm on the day of presumptive ovulation. The results correspond with previous static ultrasound studies of follicular development and in nine cycles in which both methods were employed the correlation between measurements on the same day was highly significant (r = 0·944; p
Published: 1980
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34. Irish Perinatal Society Proceedings of Meeting held in the Rotunda Hospital on 4th–5th March, 1988

Author: P. Thornton, V. Donoghue, A. Bourke, M. Walsh, I. M. Buckley, J. F. Murphy, S. Carroll, M. J. Turner, C. O’Herlihy, J. M. Stronge, D. Keane, I. N. Tobbia, P. Kelehan, M. Connolly, G. Fox, G. O’Connor, T. Clarke, M. King, T. Matthews, M. Brassil, M. Dauncey, E. C. Coles, R. G. Newcome, J. F. A. Murphy, W. A. Gorman, M. McWade, F. Timoney, D. Kenny, P. F. Chamberlain, F. R. Commerford, D. P. J. Barton, R. Connolly, Noreen Gleeson, Anita Griffith, T. D’Arcy, R. Fox, W. Reardon, N. O’Brien, W. Gorman, L. Thornton, E. Griffin, M. Wingfield, A. Bergin, S. O’Keefe, Joan Kelly, K. Connolly, C. Keohane, N. Collins, Angela H. Bell, P. J. McCullagh, G. McClure, E. Hicks, and H. L. Halliday
Subjects: Pediatrics, medicine.medical_specialty, Irish, business.industry, Family medicine, Rotunda, medicine, language, General Medicine, business, language.human_language
Published: 1988
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35. Irish Paediatric Association Annual Clinical Meeting, Limerick, May 15th–16th, 1987

Author: N. O’Brien, K. Dunne, J. Colaco, T. Clarke, F. Leahy, B. Egan-Mitchell, J. F. Cosgrove, Colleen Murphy, A. O’Meara, D. O’Donnabhain, T. A. Clarke, K. Haka Ikse, D. Hynes, J. McMenamin, D. F. Duff, Patrick F. Fottrell, T. G. Matthews, E. Tempany, D. F. Geary, M. A. Wooldridge, M. O’Regan, F. M. Stevens, D. G. Kelly, Evelyn Dykes, P. Kelehan, O. Hensey, Barry O’Donnell, M. D. Shields, Sabine Maguire, C. O’Herlihy, M. Mian, I. Koura, P. Crowley, P. Coulter, C. F. McCarthy, F. McManus, P. Curtis, D. Henvill, K. D. Connolly, A. Corboy, B. McNicholl, E. Griffin, R. Healy, M. King, D. Seckert, P. Regan, R. J. Fitzgerald, M. McKay, B. Denham, M. D. Rollins, Cecily M. Quinn, E. Piggott, D. P. Moore, Hilary Hoey, E. J. Guiney, W. A. Gorman, M. Fitzgerald, F. Breathnach, B. Connolly, B. Corcoran, R. J. M. Quinn, P. O’Connell, P. Kneafsey, H. Hendow, S. F. Cahalane, D. F. Lillis, M. R. N. Darling, J. F. Keating, Patricia Moriarty, and W. Gorman
Subjects: Pediatrics, medicine.medical_specialty, Irish, business.industry, Association (object-oriented programming), Family medicine, language, medicine, General Medicine, business, language.human_language
Published: 1988
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36. The significance of FSH elevation in young women with disorders of ovulation

Author: J H Evans, C O'Herlihy, and R J Pepperell
Subjects: Adult, Ovulation, endocrine system, medicine.medical_specialty, Urinary system, media_common.quotation_subject, Luteinising hormone, Follicle-stimulating hormone, Pregnancy, Internal medicine, medicine, Humans, Amenorrhea, Menstruation Disturbances, Retrospective Studies, General Environmental Science, media_common, business.industry, General Engineering, Estrogens, General Medicine, Luteinizing Hormone, medicine.disease, Bromocriptine, Oligomenorrhea, Endocrinology, General Earth and Planetary Sciences, Female, Follicle Stimulating Hormone, medicine.symptom, Luteinizing hormone, business, hormones, hormone substitutes, and hormone antagonists, Research Article, medicine.drug
Abstract: High serum follicle stimulating hormone (FSH) values are consistent with ovarian failure. We studied the progress of 67 women aged under 35 years with oligomenorrhoea or secondary amenorrhoea in whom the serum FSH value was greater than 20 U/1. Twenty-four patients remained amenorrhoeic, but 17 ovulated and six conceived, two on two occasions. Coincident mean serum luteinising hormone (LH) concentrations were significantly lower and mean total urinary oestrogen concentrations were significantly higher in patients who subsequently ovulated, but the degree of increase in FSH did not correlate well with later ovarian function. Treatment with oestrogens, clomiphene citrate, human pituitary gonadotrophin, and bromocriptine was of no benefit in inducing an ovarian response while FSH concentrations remained raised. Our results suggest that a considerable proportion of younger women with ovulatory disorders associated with FSH values in the menopausal range will spontaneously resume ovulation and some will conceive.
Published: 1980
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37. Neonatal seizures: the Dublin Collaborative Study

Author: W Gorman, T. G. Matthews, E. Griffin, Nora M. O'Brien, P D Curtis, T A Clarke, P. Crowley, C. O’Herlihy, M. R. N. Darling, and P O'Connell
Subjects: Pediatrics, medicine.medical_specialty, Amniotic fluid, Birth weight, Maternity hospitals, Epilepsy, Feeding behavior, Pregnancy, medicine, Birth Weight, Humans, Pregnancy, Prolonged, Labor, Induced, Asphyxia Neonatorum, business.industry, Obstetrics, Infant, Newborn, Feeding Behavior, Delivery, Obstetric, medicine.disease, Parity, Pediatrics, Perinatology and Child Health, Female, business, Ireland, Research Article, Meconium staining
Abstract: Asphyxial seizures occurred in 89 of 101,829 infants born alive at term (0.87/1000) in three large maternity hospitals from January 1980 to December 1984. These seizures were significantly associated with antenatal complications, primiparity, and prolonged pregnancy. Meconium staining of the amniotic fluid was also associated with asphyxial seizures, but there were high false positive (11%) and false negative (50%) rates. Fifteen of the infants who had seizures died (18%) and 21 (25%) were handicapped at 1 year. Outcome was most successfully predicted by the way the infant was feeding at 1-2 weeks. All infants taking more than half their estimated requirements by mouth at 1 week were normal, and those still being fed by tube at 2 weeks were handicapped.
Published: 1988
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38. SCREENING FOR FETAL RISK WITH URINARY OESTROGEN: CREATININE RATIO AT 34 WEEKS

Author: R. H. Martin and C. O'Herlihy
Subjects: medicine.medical_specialty, Placenta Diseases, Pregnancy Trimester, Third, Urinary system, Urology, Physical examination, chemistry.chemical_compound, Pregnancy, Prenatal Diagnosis, medicine, Fetal distress, Humans, Fetal Death, Morning, Gynecology, Creatinine, Fetus, medicine.diagnostic_test, business.industry, Smoking, Obstetrics and Gynecology, Estrogens, Placental Insufficiency, medicine.disease, Pregnancy Complications, Fetal Diseases, Blood pressure, chemistry, Gestation, Female, business
Abstract: Summary The urinary oestrogen :creatinine (O/C) ratio was measured in first morning specimens of 261 women at 34 weeks gestation to assess prospectively its potential in predicting fetal complications. Forty-two patients (16.1 per cent) had low O/C ratios. All three stillbirths in the series occurred in this group and the incidences of fetal growth retardation and fetal distress in labour were also significantly increased. These complications were unusual when the O/C ratio was high. The O/C ratio at 34 weeks reflected fetal well-being more accurately than clinical examination or blood pressure measurement. The mean O/C ratios of cigarette smokers and non-smokers were similar, although smokers were delivered of lighter babies. Measurement of the urinary O/C ratio is simple and inexpensive. Used as a screening test at 34 weeks it appears to provide an early and fairly reliable indication of reduced placental function.
Published: 1980
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39. Vaginal prostaglandin E2 gel and breech presentation

Author: C. O'Herlihy
Subjects: medicine.medical_specialty, Prostaglandin, Cervix Uteri, Labor Presentation, chemistry.chemical_compound, Pregnancy, Breech presentation, medicine, Humans, Labor, Induced, Prostaglandin E2, Breech Presentation, Cervix, reproductive and urinary physiology, Gynecology, Fetus, Obstetrics, business.industry, Prostaglandins E, Obstetrics and Gynecology, Fetal Presentation, Induction of labor, female genital diseases and pregnancy complications, medicine.anatomical_structure, Reproductive Medicine, chemistry, Unripe cervix, Vaginal Creams, Foams, and Jellies, Female, business, medicine.drug
Abstract: Intravaginal prostaglandin (PG) E 2 has been shown to ripen the cervix before induction and to shorten labor when the fetal presentation is cephalic. This study reports the influence of PGE 2 gel on induction and labor in 13 primigravid patients with unfavorable cervixes and breech presentation. The results were compared with 25 similarly treated primigravidae with cephalic presentations. Comparable cervical ripening was achieved in the breech and cephalic groups; labors were of similar duration and the incidence of cesarean section was not significantly different in the breech patients. There were no unwanted fetal or maternal effects associated with the gel. PGE 2 gel is an effective aid to induction of labor when the cervix is unfavorable and the breech presents in otherwise uncomplicated pregnancies.
Published: 1981
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40. Incremental Clomiphene Therapy

Author: John McBain, James B. Brown, M. A. Smith, L Sandri, Roger J. Pepperell, and C O'Herlihy
Subjects: Infertility, medicine.medical_specialty, medicine.drug_class, business.industry, medicine.medical_treatment, Urology, Obstetrics and Gynecology, General Medicine, medicine.disease, Anovulation, Regimen, Follicle-stimulating hormone, Endocrinology, Estrogen, Internal medicine, medicine, Ovulation induction, Gonadotropin, Luteinizing hormone, business
Abstract: Thirty anovulatory patients, previously unresponsive to clomiphene citrate in standard dosage, were treated with a new incremental method of clomiphene therapy. Clomiphene was given continuously with dosage increments every 5 days, up to a maximum dose of 3750 mg, and ovarian response was monitored with urinary estrogen estimation and with ultrasound. Twenty-one patients (70%) ovulated on this regimen and 8 (27%) conceived; 6 patients who ovulated but did not conceive had other infertility factors. Clomiphene response was associated with a progressive rise in follicle-stimulating hormone, luteinizing hormone, and estrogen excretion; these parameters were unchanged in nonresponders. Side effects of treatment were minimal and only 1 case of hyperstimulation occurred. Preliminary testing with estrogen-amplified gonadotropin-releasing hormone did not differentiate responders from nonresponders. Incremental clomiphene treatment appears to be a less complicated alternative for patients who would otherwise require exogenous gonadotropin therapy.
Published: 1982
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41. Induction of ovulation. Ovulation induction therapy: indications and monitoring

Author: C, O'Herlihy
Subjects: Ovulation Induction, Ovary, Humans, Female, Ovarian Diseases, Amenorrhea
Published: 1986

42. Incremental clomiphene therapy: a new method for treating persistent anovulation

Author: C, O'Herlihy, R J, Pepperell, J B, Brown, M A, Smith, L, Sandri, and J C, McBain
Subjects: Adult, Dose-Response Relationship, Drug, Ovulation Induction, Pregnancy, Humans, Estrogens, Female, Follicle Stimulating Hormone, Luteinizing Hormone, Pituitary Hormone-Releasing Hormones, Menstruation Disturbances, Anovulation, Clomiphene
Abstract: Thirty anovulatory patients, previously unresponsive to clomiphene citrate in standard dosage, were treated with a new incremental method of clomiphene therapy. Clomiphene was given continuously with dosage increments every 5 days, up to a maximum dose of 3750 mg, and ovarian response was monitored with urinary estrogen estimation and with ultrasound. Twenty-one patients (70%) ovulated on this regimen and 8 (27%) conceived; 6 patients who ovulated but did not conceive had other infertility factors. Clomiphene response was associated with a progressive rise in follicle-stimulating hormone, luteinizing hormone, and estrogen excretion; these parameters were unchanged in nonresponders. Side effects of treatment were minimal and only 1 case of hyperstimulation occurred. Preliminary testing with estrogen-amplified gonadotropin-releasing hormone did not differentiate responders from nonresponders. Incremental clomiphene treatment appears to be a less complicated alternative for patients who would otherwise require exogenous gonadotropin therapy.
Published: 1981

43. Heparinoid cream in pregnancy--associated superficial thrombophlebitis

Author: C, O'Herlihy
Subjects: Adult, Pregnancy Complications, Leg, Heparinoids, Pregnancy, Humans, Female, Puerperal Disorders, Thrombophlebitis
Published: 1980

44. Letter: Planned delivery

Author: C, O'Herlihy and D, MacDonald
Subjects: Time Factors, Hospital Administration, Pregnancy, Humans, Female, Labor, Induced, Seasons, Hospitals, Maternity, Ireland
Published: 1975

45. Significance of raised immunoglobulin M levels in cord blood of small-for-gestational-age infants

Author: C O'Herlihy and T G Matthews
Subjects: medicine.medical_specialty, Cord, Infections, ABO Blood-Group System, Drug Therapy, Pregnancy, medicine, Humans, Pregnancy Complications, Infectious, biology, Obstetrics, business.industry, Incidence (epidemiology), Infant, Newborn, medicine.disease, Fetal Blood, Toxoplasmosis, Obstetric Labor Complications, Immunoglobulin M, Cord blood, Pediatrics, Perinatology and Child Health, Immunology, Infant, Small for Gestational Age, biology.protein, Small for gestational age, Syphilis, Female, business, Research Article
Abstract: Cord IgM values were determined in small-for-gestational-age infants born at Hammersmith Hospital during a 5 1/2-year period. 121 (12.5%) infants had levels more than 0.2 g/l; in 92 these were between 0.21 and 0.3 g/l. In only 18 (14.8%) was a level of 0.4 g/l exceeded, and 5 proved cases of intrauterine infection--rubella (2), syphilis (2), and toxoplasmosis (1)--were in this group. The factor most often associated with cord IgM more than 0.4 g/l was prolonged rupture of the membranes. There was an increased incidence of blood group B among the mothers, probably reflecting the greater number of nonCaucasian women giving birth to small-for-gestational-age infants. Determination of cord IgM did not help significantly indiagnosis.
Published: 1978

46. Use of ultrasound in monitoring ovulation induction with human pituitary gonadotropins

Author: C, O'Herlihy, J H, Evans, J B, Brown, L J, de Crespigny, and H P, Robinson
Subjects: Dose-Response Relationship, Drug, Follicular Phase, Ovulation Induction, Pregnancy, Gonadotropins, Pituitary, Ovary, Humans, Estrogens, Female, Chorionic Gonadotropin, Monitoring, Physiologic, Ultrasonography
Abstract: Serial follicular growth was studied using real-time ultrasound scanning in 26 anovulatory patients in 55 cycles stimulated with exogenous human pituitary gonadotropin (hPG) and human chorionic gonadotropin (hCG). Dosage was monitored with urinary total estrogen estimations. The ultrasound findings were not made known to the attending physician. Forty-four cycles (80%) were ovulatory, and conception occurred in 13. The mean follicular diameter of 17 to 25 mm at ovulation corresponded with the range observed in spontaneous cycles, although the rate of follicular growth was faster with hPG. On the day the ovulatory dose of hCG was given, as determined by the first urinary estrogen value greater than 50 microgram/24 hours, estrogen excretion was similar whether single or multiple follicles of potential ovulatory size were present, but mean follicular diameters were significantly smaller when there was more than 1 follicle. During the last 4 days before ovulation, the mean diameters in conceptual cycles increased from 14.2 mm to 19.7 mm, values similar to those observed in spontaneous cycles, but different growth patterns occurred in some nonconceptual cycles. Ovarian hyperstimulation was identified by ultrasound scan in 4 of 5 cycles before urinary estrogen excretion exceeded the normal range. Although ultrasound scan does not supplant estrogen monitoring, it can assist in the early detection of hyperstimulation, in the more accurate timing of the ovulatory dose of hCG, and in the withholding of hCG when 3 or more ovulations are possible. It is recommended that ultrasound examination be performed in all patients before the ovulation-inducing dose of hCG is given to provide information on the number of follicles that are likely to ovulate and thus avoid conception of more than twins.
Published: 1982

47. Ultrasound timing of human chorionic gonadotropin administration in clomiphene-stimulated cycle

Author: C, O'Herlihy, R J, Pepperell, and H P, Robinson
Subjects: Ovarian Follicle, Ovulation Induction, Pregnancy, Cervix Mucus, Humans, Female, Chorionic Gonadotropin, Infertility, Female, Clomiphene, Ultrasonography
Abstract: Seventeen patients treated with clomiphene citrate were examined using real-time ultrasound timing 28 ovulatory cycles to determine the pattern of follicular development under clomiphene stimulation. The rate of growth was faster, but the follicular diameter range at ovulation was similar to that during spontaneous cycles. This information was used to time midcycle human chorionic gonadotropin (hCG) administration in over 97 cycles in 21 patients responsive to clomiphene who had not conceived. When hCG was given when the mean follicular diameter reached 18 mm, 92% of these cycles were ovulatory. Fourteen patients (67%) conceived within 6 ovulatory treatment cycles. Five of 7 patients (71%) who did not conceive were found to have endometriosis at laparoscopy. Midcycle cervical scores were significantly lower in clomiphene-treated as compared with spontaneous ovulatory cycles, and additional treatment with ethinyl estradiol did not effect a significant improvement. Timing of midcycle hCG using ultrasound is an effective method of inducing ovulation in patients in whom an estrogenic follicular response without ovulation is obtained with clomiphene treatment.
Published: 1982

48. Neonatal stridor with Larsen's syndrome

Author: C, O'Herlihy and N, O'Brien
Subjects: Male, Laryngeal Cartilages, Face, Infant, Newborn, Joint Dislocations, Humans, Abnormalities, Multiple, Syndrome, Joint Diseases, Respiration Disorders
Published: 1977

49. Perinatal aspects of preterm delivery

Author: C, O'Herlihy and N, O'Brien
Subjects: Pregnancy Complications, Fetus, Pregnancy, Infant Mortality, Infant, Newborn, Humans, Female, Growth, Delivery, Obstetric, Perinatology, Infant, Newborn, Diseases, Infant, Premature, Jaundice, Neonatal
Published: 1977

50. Successful pregnancy following ovulation induction with pulsatile GnRH

Author: C, O'Herlihy, J, Stanley, and D, Powell
Subjects: Adult, Ovulation Induction, Pregnancy, Humans, Female, Infusions, Parenteral, Infertility, Female, Pituitary Hormone-Releasing Hormones
Published: 1985

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