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1. Caractérisation spectrale et temporelle de l'émission X issue de l'interaction laser-agrégats

Author

C. Bonte, H. Jouin, Marion Harmand, B. Pons, J. J. Santos, S. Micheau, C. Fourment, and Olivier Peyrusse

Subjects
General Physics and Astronomy
Abstract

Les agregats de gaz rares constituent un etat de la matiere intermediaire entre les cibles solides massives et les atomes en phase gazeuse. Il a ete demontre que les agregats irradies sont sources d'ions, d'electrons, de neutrons ainsi que de rayonnement allant du visible aux X durs. Cette source peut-etre produite avec un taux de repetition eleve et a l'avantage de ne pas produire de debris, dommageables pour les optiques notamment, et de presenter une tres forte conversion de l'energie laser incidente. Nous nous interessons au rayonnement X particulierement, en le caracterisant en intensite, spectre et duree, comme prealable a toute application de cette source X et comme moyen privilegie d'etude de la physique des plasmas nanometriques chauds et denses. En collaboration avec l'INRS-Energie (Varenne, Qc, Canada), nous avons mis en oeuvre une camera a balayage de fente dont la resolution temporelle est de 800 fs rms. En focalisant des impulsions laser courtes (30fs - 5ps) et intenses (jusqu'a 10 17 W/cm 2 ) sur des agregats d'argon dont le rayon varie de 15 a 30nm, nous avons demontre que l'emission X dont l'energie est superieure a 2 keV est plus courte que 2ps, limite par la resolution temporelle. En couplant la camera a un cristal tronconique, dont la conception a ete realisee au LULI (Palaiseau, France), nous nous sommes interesses au rayonnement de couche K dans la gamme 2,9 - 3,2 keV. Nous avons demontre que ce rayonnement a une duree inferieure a 3ps (limite de la resolution temporelle), et que les raies etaient emises avec un ecart relatif inferieur a 1 ps. Une simulation basee sur le modele nano-plasma propose par T. Ditmire et sur le code collisionnel-radiatif Transpec a ete developpee au CELIA. Les spectres X resolus en temps calcules reproduisent a la fois la brievete d'emission du rayonnement X et les etats de charge eleves observes.

Published
2006
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2. Broadband, high dynamics and high resolution charge coupled device-based spectrometer in dynamic mode for multi-keV repetitive x-ray sources

Author

C. Bonte, Marion Harmand, S. Hulin, N. Arazam, C. Fourment, Fabien Dorchies, T. Caillaud, Dominique Descamps, S. Petit, Joao Santos, Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Deutsches Elektronen-Synchrotron [Zeuthen] (DESY), Helmholtz-Gemeinschaft = Helmholtz Association, Pôle Fromager AOP du Massif Central, Laboratoire d'Ecologie Microbienne - UMR 5557 (LEM), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Ecole Nationale Vétérinaire de Lyon (ENVL)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Ecole Nationale Vétérinaire de Lyon (ENVL), Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etudes Lasers Intenses et Applications ( CELIA ), Université de Bordeaux ( UB ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Centre National de la Recherche Scientifique ( CNRS ), DAM Île-de-France ( DAM/DIF ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), Deutsches Elektronen-Synchrotron [Zeuthen] ( DESY ), Helmholtz-Gemeinschaft, Ecologie microbienne ( EM ), Centre National de la Recherche Scientifique ( CNRS ) -Ecole Nationale Vétérinaire de Lyon ( ENVL ) -Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique ( INRA ) -VetAgro Sup ( VAS ), Université Claude Bernard Lyon 1 ( UCBL ), Ecole Nationale Vétérinaire de Lyon ( ENVL ), Laboratoire d'optique appliquée ( LOA ), École Nationale Supérieure de Techniques Avancées ( Univ. Paris-Saclay, ENSTA ParisTech ) -École polytechnique ( X ) -Centre National de la Recherche Scientifique ( CNRS ), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Ecole Nationale Vétérinaire de Lyon (ENVL), Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Vétérinaire de Lyon (ENVL)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS), and Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-École Nationale Supérieure de Techniques Avancées (ENSTA Paris)

Subjects
Physics, [PHYS]Physics [physics], Photon, [ PHYS ] Physics [physics], Spectrometer, business.industry, Resolution (electron density), Detector, Laser, 01 natural sciences, 010305 fluids & plasmas, law.invention, Optics, law, 0103 physical sciences, Charge-coupled device, Atomic number, 010306 general physics, business, Instrumentation, Energy (signal processing), ComputingMilieux_MISCELLANEOUS
Abstract

We present a new operating mode, using a charged coupled device as dispersionless spectrometer dedicated to repetitive x-ray sources in the multi-keV domain. This enables to get spectra with high statistics in a short acquisition time and a way compatible with the operation of other diagnostics requiring accumulation. Several reconstruction algorithms for the spreading events are discussed, and a near Fano-limited resolution is demonstrated by using single pixel events. In this case, a method to take into account partial canceling of the events is presented. Experimental characterization and detailed modeling of the detector are performed, which allow to determine absolute number of photon with +/-35% accuracy. Characterization of the 5-25 keV x rays emitted by a short pulse laser-produced plasma is reported, as well as their dependency with the atomic number, the laser duration, and energy.

Published
2009

3. Observation of Subpicosecond X-Ray Emission from Laser-Cluster Interaction

Author

Fabien Dorchies, F. Blasco, T. Caillaud, C. Bonte, C. Fourment, Olivier Peyrusse, Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)

Subjects
[PHYS]Physics [physics], Physics, X-ray, Electron shell, General Physics and Astronomy, Time resolution, Laser, law.invention, Photon emission, law, Cluster (physics), Atomic physics, Ultrashort pulse, ComputingMilieux_MISCELLANEOUS
Abstract

We present the first experimental evidence of the subpicosecond duration of x-ray pulses emitted from laser-irradiated clusters, demonstrating the suitability of such a debris free target for ultrafast x-ray science applications. The $K$-shell emission ($\ensuremath{\sim}3\text{ }\text{ }\mathrm{keV}$) from large Ar clusters ($6\ifmmode\times\else\texttimes\fi{}{10}^{5}$ to $4\ifmmode\times\else\texttimes\fi{}{10}^{6}$ atoms) is time resolved, when irradiated by ultrashort (40 fs to 5 ps) and intense laser pulses (${10}^{15\ensuremath{-}17}\text{ }\text{ }\mathrm{W}/{\mathrm{cm}}^{2}$). The observations are supported by hydrodynamical and collisional-radiative calculations, that reproduce the extremely short x-ray pulse duration.

Published
2008
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4. Dynamics of rare gas nanoclusters irradiated by short and intense laser pulses

Author

Fabien Dorchies, S. Micheau, J. J. Santos, Marion Harmand, H. Jouin, Bernard Pons, C. Fourment, Olivier Peyrusse, C. Bonte, Centre d'Etudes Lasers Intenses et Applications (CELIA), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), Laboratoire d'Etudes Aérodynamiques (LEA), Centre National de la Recherche Scientifique (CNRS)-ENSMA-Université de Poitiers, Deutsches Elektronen-Synchrotron [Zeuthen] (DESY), Helmholtz-Gemeinschaft = Helmholtz Association, Démarche intégrée pour l'obtention d'aliments de qualité (UMR Qualisud), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Avignon Université (AU)-Université de La Réunion (UR)-Université de Montpellier (UM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), and Université de Poitiers-ENSMA-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS]Physics [physics], Nuclear and High Energy Physics, Radiation, Materials science, Streak camera, Laser, 01 natural sciences, 010305 fluids & plasmas, law.invention, Nanoclusters, Ion, law, Picosecond, Excited state, Ionization, 0103 physical sciences, Atomic physics, 010306 general physics, Ultrashort pulse, ComputingMilieux_MISCELLANEOUS
Abstract

We report on a joint experimental–theoretical effort to shed light on the dynamics of rare gas (Ar) nanoclusters irradiated by short and intense laser pulses. The experiments employ a streak camera coupled to a conical crystal to yield energy- and time-resolved X-ray spectra, in the keV range on picosecond scale. These spectra display ultrafast subpicosecond ionization dynamics, leading to highly charged states such as Ar16+, and indicate that the duration of the energetic X-rays is less than the experimental 1.3 ps temporal resolution. The theoretical calculations rely on the well-known nanoplasma model, which has been improved to represent the collisional ionization processes that are of importance in nanoplasma dynamics. Allowance is made for high-order ionization transitions involving intermediate excited states. The simulations indicate significant populations of excited states of highly charged ions, in agreement with the experimental findings. Further, detailed collisional-radiative calculations indicate that the duration of the X-ray bursts is less than 100 fs.

Published
2007
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5. High dynamic range streak camera for subpicosecond time-resolved x-ray spectroscopy

Author

J. P. Geindre, V. Pitre, J. C. Kieffer, P. Audebert, C. Bonte, Fabien Dorchies, Sebastien Magnan, Marion Harmand, Deutsches Elektronen-Synchrotron [Zeuthen] (DESY), Helmholtz-Gemeinschaft = Helmholtz Association, Centre d'Etudes Lasers Intenses et Applications (CELIA), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), Institut National de la Recherche Scientifique [Québec] (INRS), Laboratoire pour l'utilisation des lasers intenses (LULI), Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), and Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Physics, [PHYS]Physics [physics], Spectrometer, business.industry, Streak camera, Detector, 02 engineering and technology, 021001 nanoscience & nanotechnology, 01 natural sciences, Optical switch, Optics, Signal-to-noise ratio, Temporal resolution, 0103 physical sciences, Optoelectronics, 010306 general physics, 0210 nano-technology, business, Instrumentation, High dynamic range, ComputingMilieux_MISCELLANEOUS, Jitter
Abstract

The full characterization of a time resolved x-ray spectrometer is presented. It is based on the coupling of a conical crystal with a subpicosecond x-ray streak camera. The detector is designed to operate in accumulation mode at high repetition rate (up to 1 kHz) allowing signal to noise ratio as high as 10(4):1. Optical switches have been used to limit the jitter induced in the subpicosecond range, demonstrating the very long term stability (a few hours) of the entire device. The data analysis have been developed to get the spectral and temporal resolution of an ultrashort laser-plasma-based x-ray source.

Published
2007

6. Ultra short x-ray source from laser-clusters interaction

Author

C. Fourment, T. Caillaud, Olivier Peyrusse, Fabien Dorchies, J. Stevefelt, C. Bonte, M. Harmand, Joao Santos, and F. Blasco

Subjects
Physics, law, Astrophysics::High Energy Astrophysical Phenomena, Femtosecond, Radius, Emission spectrum, Plasma, Atomic physics, Laser, Absorption (electromagnetic radiation), Atomic, molecular, and optical physics, Ion, law.invention
Abstract

Interaction of femtosecond (30 fs-5 ps) and intense (up to 1017 W/cm2) laser pulses with Ar clusters (180 to 350 Å radius) has been studied. The laser absorption and the cluster heating have been measured using different diagnostics, demonstrating the production of very hot and dense plasmas, in the keV range. A special attention has been devoted to the K-shell x-ray emission spectra (2.9-3.3 keV). X-ray emission has been observed from ions in very high charge states (Ar16+). Time-resolved measurements have been performed, giving evidence, for the first time, of extremely short x-ray pulses down to the sub-picosecond. Simulations based on both an hydrodynamic model and collisional-radiative atomic physics reveal an extremely brief x-ray emission burst consistent with measurements.© (2006) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.

Published
2006
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7. Time-resolved X-ray spectra of hot & dense plasmas from laser-clusters interaction

Author

T. Caillaud, C. Bonte, J. J. Santos, J. Stevefelt, R. Fedosejevs, Marion Harmand, C. Fourment, Olivier Peyrusse, F. Blasco, Fabien Dorchies, Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoire d'Etudes Aérodynamiques (LEA), Université de Poitiers-ENSMA-Centre National de la Recherche Scientifique (CNRS), Deutsches Elektronen-Synchrotron [Zeuthen] (DESY), Helmholtz-Gemeinschaft = Helmholtz Association, Laboratoire pour l'utilisation des lasers intenses (LULI), Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), and Centre National de la Recherche Scientifique (CNRS)-ENSMA-Université de Poitiers

Subjects
Physics, [PHYS]Physics [physics], Range (particle radiation), Astrophysics::High Energy Astrophysical Phenomena, General Physics and Astronomy, Plasma, Radius, Laser, Ion, law.invention, law, Femtosecond, Emission spectrum, Atomic physics, Absorption (electromagnetic radiation), ComputingMilieux_MISCELLANEOUS
Abstract

Interaction of femtosecond (30 fs - 5 ps) and intense (up to 10 17 W/cm 2 ) laser pulses with Ar clusters (180 to 350 A radius) has been studied. The laser absorption and the cluster heating have been measured using different diagnostics, demonstrating the production of very hot and dense plasmas, in the keV range. A special attention has been devoted to the K-shell x-ray emission spectra (2.9-3.3 keV). X-ray emission has been observed from ions in very high charge states (Ar 16+ ). Time-resolved measurements have been performed, giving evidence, for the first time, of extremely short x-ray pulses (

Published
2006

8. Experimental study of x-ray emission in laser-cluster interaction

Author

T. Caillaud, Patrick Mora, Olivier Peyrusse, Fabien Dorchies, F. Blasco, and C. Bonte

Subjects
Physics, Argon, Streak camera, Astrophysics::High Energy Astrophysical Phenomena, chemistry.chemical_element, Plasma, Laser, law.invention, chemistry, law, Ionization, Cluster (physics), Emission spectrum, Atomic physics, Cluster expansion
Abstract

Rare gas cluster jets are an intermediate medium between solid and gas targets. Laser-cluster jets interaction may generate a great number of energetic particles such as X-rays, UV, high harmonics, ions, electrons and neutrons. To understand all the mechanisms involved in this interaction we need to make a complete study of individual cluster response to an ultra-short laser pulse. We studied the laser interaction with our Argon cluster gas jet, which is well characterized in cluster size and density, to enlarge the knowledge of this interaction. We measured absorption, heating and X-ray emission spectra versus laser parameters and clusters size (~15-30 nm). We show that there is a strong refraction effect on laser propagation due to the residual gas density. This effect was confirmed by laser propagation simulation with a cylindrical 2D particle code WAKE. The role played by refraction was to limit maximum laser intensity on the focal spot and to increase interaction volume. By this way, X-ray emission was observed with laser intensity not so far from the ionization threshold (few 10 14 W.cm -2 ). We also studied plasma expansion both at cluster scale and focal volume scale and deduced the deposited energy distribution as a function of time. Thanks to a simple hydrodynamic model, we used these results to study cluster expansion. X-ray emission is then simulated by TRANSPEC code in order to reproduce X-ray spectra and duration. Those results revealed an extremely brief X-ray emission consistent with a preliminary measure by streak camera (~ps).

Published
2005
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9. Investigation of laser-irradiated Ar cluster dynamics from K-shell x-ray emission measurements

Author

Fabien Dorchies, C. Bonte, J. Stevefelt, H. Jouin, Bernard Pons, T. Caillaud, S. Micheau, F. Blasco, Centre d'Etudes Lasers Intenses et Applications (CELIA), and Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Physics, Resolution (electron density), X-ray, Electron shell, Order (ring theory), Laser, Spectral line, Ion, law.invention, law, [PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], Atomic physics, Circular polarization, 52.50.Jm, 52.38.Ph, 32.30.Rj
Abstract

Intense (up to a few ${10}^{17}\phantom{\rule{0.3em}{0ex}}\mathrm{W}∕{\mathrm{cm}}^{2}$) femtosecond (down to $40\phantom{\rule{0.3em}{0ex}}\mathrm{fs}$) laser pulses are focused onto a partially clusterized argon gas jet. The target was previously characterized and optimized in order to get a homogeneous and dense jet of clusters with a well controlled size. The interaction leads to x-ray emission that is absolutely calibrated and spectrally resolved using a high resolution time-integrated spectrometer in the $K$-shell range (from $2.9\phantom{\rule{0.3em}{0ex}}\text{to}\phantom{\rule{0.3em}{0ex}}4.3\phantom{\rule{0.3em}{0ex}}\mathrm{keV}$). X-ray spectra are investigated as a function of different laser temporal parameters such as the nanosecond prepulse contrast, the laser pulse duration, and the femtosecond delay between two different laser pulses. The cluster size ranges from $180\phantom{\rule{0.3em}{0ex}}\text{to}\phantom{\rule{0.3em}{0ex}}350\phantom{\rule{0.3em}{0ex}}\mathrm{\AA{}}$ and irradiation by laser pulses with both linear and circular polarization is investigated. The experimental results are discussed in terms of the laser-cluster interaction dynamics. They are compared with the predictions of collision-dominated nanoplasma models. However, further interaction processes are required in order to explain the observed characteristic lines demonstrating highly charged ions up to ${\mathrm{Ar}}^{16+}$.

Published
2005
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10. Time-dependent study of K-shell satellite line structure from L-shell ions in ultra-short laser argon cluster experiments

Author

A. Ya. Faenov, T. A. Pikuz, F. Blasco, C. Salin, G. C. Junkel-Vives, T. Caillaud, I. Yu. Skobelev, A. I. Magunov, C. Stenz, Fabien Dorchies, Joseph Abdallah, C. Bonte, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), BIOVERT (BIOVERT), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Centre d'Etudes Lasers Intenses et Applications (CELIA), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Laboratoire pour l'utilisation des lasers intenses (LULI), Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS]Physics [physics], Radiation, Argon, Materials science, Electron shell, chemistry.chemical_element, Plasma, Laser, 01 natural sciences, Atomic and Molecular Physics, and Optics, Spectral line, 010305 fluids & plasmas, law.invention, Ion, chemistry, law, 0103 physical sciences, Femtosecond, Cluster (physics), Atomic physics, 010306 general physics, Spectroscopy, ComputingMilieux_MISCELLANEOUS
Abstract

The interaction of high-power, ultra-short, femtosecond laser pulses with matter, particularly solids and atomic gas clusters has been an area of extensive research in recent years. In particular, gas cluster targets, with their high densities and resistance to heat conduction, combine the advantages of both gas and solid targets. High temperature and high-density plasmas with satellite lines from multiply charged ions have been observed: 2p-1s emissions in Li-like through F-like ions appear in the experimental spectrum. The experimental satellite spectra show sensitivity to pulse duration, laser contrast, and cluster size. Since the laser energy is deposited in such a short timescale, a time-dependent model is being developed to study the plasma formation in such systems. In the present work, preliminary time-integrated spectra simulated from this model are presented assuming different initial conditions for the pre-plasma. The computational model also includes a provision for non-thermal electrons at energies substantially above the mean plasma temperature.

Published
2003

11. On the interaction of femtosecond laser pulses with cluster targets

Author

François Salin, C. Stenz, Fabien Dorchies, P. D' Oliveira, J. Abdallach, T. A. Pikuz, C. Bonte, P. Monot, Vladimir A. Gasilov, G. C. Junkel-Vives, B. Yu. Sharkov, F. Blasco, I. Yu. Skobelev, A. I. Magunov, T. Auguste, S. Hulin, A. S. Boldarev, T. Caillaud, A. Ya. Faenov, BIOVERT (BIOVERT), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Service des Photons, Atomes et Molécules (SPAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Serveurs Laser (SLIC), Institut Rayonnement Matière de Saclay (IRAMIS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire Interactions, Dynamiques et Lasers (ex SPAM) (LIDyl), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Pôle Fromager AOP du Massif Central, Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Laboratoire pour l'utilisation des lasers intenses (LULI), Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), and Dorchies, Fabien

Subjects
[PHYS]Physics [physics], Jet (fluid), Materials science, General Physics and Astronomy, Plasma, Laser, 01 natural sciences, Spectral line, [PHYS] Physics [physics], 010305 fluids & plasmas, law.invention, law, Picosecond, 0103 physical sciences, Femtosecond, Cluster (physics), Emission spectrum, Atomic physics, 010306 general physics, ComputingMilieux_MISCELLANEOUS
Abstract

The heating of clusters by femtosecond laser pulses is studied theoretically and experimentally. Both the formation of a cluster target and the results of experimental studies of the cluster plasma by the methods of X-ray emission spectroscopy are considered. A numerical model of cluster formation in a supersonic gas jet is proposed. It is shown that detailed studies of two-phase gas-dynamic processes in a nozzle forming the jet give the spatial distributions of all parameters required for the correct calculation of the cluster heating by short laser pulses. Calculations of nozzles of different configurations show that in a number of cases an almost homogeneous cluster target can be formed, whereas in other cases the distributions of parameters prove to be not only inhomogeneous but also even nonmonotonic. A simple physical model of the plasma production by a femtosecond laser pulse and a picosecond prepulse is proposed. It is shown that a comparison of X-ray spectra with detailed calculations of the ion kinetics makes it possible to determine the main parameters of the plasma being produced.

Published
2002

12. Evidence of supercritical density in 45-fs-laser-irradiated Ar-cluster plasmas

Author

T. Caillaud, A. I. Magunov, Fabien Dorchies, T. A. Pikuz, A. Ya. Faenov, I. Yu. Skobelev, G. C. Junkel-Vives, C. Bonte, Joseph Abdallah, C. Stenz, François Salin, F. Blasco, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Laboratoire pour l'utilisation des lasers intenses (LULI), Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), BIOVERT (BIOVERT), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)

Subjects
Physics, [PHYS]Physics [physics], Argon, Order (ring theory), chemistry.chemical_element, Plasma, Electron, Laser, 7. Clean energy, 01 natural sciences, Atomic and Molecular Physics, and Optics, Spectral line, 010305 fluids & plasmas, law.invention, chemistry, law, 0103 physical sciences, Irradiation, Emission spectrum, Atomic physics, 010306 general physics, ComputingMilieux_MISCELLANEOUS
Abstract

Plasmas have been created by irradiating atomic clusters of argon with high-contrast, ultrashort $(l100\mathrm{fs})$ laser pulses and recording the corresponding K-shell emission spectra. The high-resolution Ar K-shell spectra were analyzed using a theoretical two-temperature collisional-radiative model of irradiated atomic clusters incorporating the effects of highly energetic electrons $(\ensuremath{\sim}5\mathrm{keV}).$ Comparison of the measured spectrum with the calculations indicates that a supercritical density near ${N}_{e}=2\ifmmode\times\else\texttimes\fi{}{10}^{22}{\mathrm{cm}}^{\ensuremath{-}3}$ was attained in the shortest-pulse and highest-contrast shots. Results from additional experiments using pulses on the order of 300--400 fs are also consistent with a hydrodynamic model of laser-cluster interactions.

Published
2002

13. Observation of dielectronic satellites in the K-spectrum of argon ions in plasma produced by femtosecond laser pulses

Author

T. A. Pikuz, A. Ya. Faenov, C. Stenz, F. Blasco, Fabien Dorchies, C. Bonte, Pascal Quinet, I. Yu. Skobelev, A. I. Magunov, Emile Biémont, T. Caillaud, François Salin, BIOVERT (BIOVERT), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), IPNAS, Université de Liège, Astrophysique et Spectroscopie, Université de Mons-Hainaut, Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Laboratoire pour l'utilisation des lasers intenses (LULI), Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), and Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB)

Subjects
[PHYS]Physics [physics], education.field_of_study, Materials science, Argon, Plasma parameters, Population, General Physics and Astronomy, chemistry.chemical_element, Plasma, Laser, 01 natural sciences, 010305 fluids & plasmas, law.invention, Ion, chemistry, Physics::Plasma Physics, law, 0103 physical sciences, Femtosecond, Physics::Atomic Physics, Spectral resolution, Atomic physics, 010306 general physics, education, ComputingMilieux_MISCELLANEOUS
Abstract

The satellite structure of 1s2p1,3P1-1s21S0 lines of the He-like argon ion in plasma produced by a 45-fs laser pulse in a gas-jet cluster target is measured with a high spectral resolution. Radiation transitions 2p → 1s from autoionizing states (AISs) are detected for ions ranging from Li-like to F-like. The spectrum observed is theoretically simulated with the use of the spectroscopic data for the AISs of multicharged ions obtained within the multiconfiguration relativistic Hartree-Fock method. Good agreement with experimental data is obtained when the main population channels of these states are taken into account for typical values of cluster-target plasma parameters.

Published
2002

14. X-ray spectroscopy diagnostic of a plasma produced by femtosecond laser pulses irradiating a cluster target

Author

Vladimir A. Gasilov, A. S. Boldarev, B. Yu. Sharkov, F. Blasco, P. A. Loboda, S. Hulin, T. Auguste, Fabien Dorchies, T. Caillaud, T. A. Pikuz, François Salin, A. Ya. Faenov, G. V. Baidin, I. A. Litvinenko, C. Stenz, Pascal D'Oliveira, V. V. Popova, P. Monot, G. C. Junkel-Vives, A. I. Magunov, S. Dobosz, I. Yu. Skobelev, J. Abdallach, C. Bonte, BIOVERT (BIOVERT), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Service des Photons, Atomes et Molécules (SPAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Serveurs Laser (SLIC), Institut Rayonnement Matière de Saclay (IRAMIS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire Interactions, Dynamiques et Lasers (ex SPAM) (LIDyl), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Pôle Fromager AOP du Massif Central, Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Laboratoire pour l'utilisation des lasers intenses (LULI), Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Dorchies, Fabien, Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), and Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB)

Subjects
Femtosecond pulse shaping, [PHYS]Physics [physics], Materials science, Plasma parameters, business.industry, General Physics and Astronomy, Plasma, Laser, 01 natural sciences, 010305 fluids & plasmas, law.invention, [PHYS] Physics [physics], Optics, Multiphoton intrapulse interference phase scan, Physics::Plasma Physics, law, 0103 physical sciences, Femtosecond, Plasma diagnostics, Atomic physics, 010306 general physics, Spectroscopy, business, ComputingMilieux_MISCELLANEOUS
Abstract

The parameters of a plasma produced upon the interaction of ultrashort laser pulses with cluster targets are measured by the methods of X-ray spectroscopy. The dependence of the plasma parameters on the initial properties of a cluster target (the design of a supersonic nozzle, the average size of clusters, the spatial inhomogeneity) and the laser pulse properties (its duration and contrast) is studied. The plasma diagnostics is performed using the model of formation of emission spectra, which was proposed earlier and includes a number of fitting parameters, which provide good agreement with experimental spectra. The systematic experimental studies performed by us showed that our model of cluster heating by ultrashort pulses is indeed a physical model, and the fitting parameters represent the average values of plasma parameters in the corresponding space-time regions.

Published
2002

15. Influence of ultrashort laser pulse duration on the X-ray emission spectrum of plasma produced in cluster target

Author

T. A. Pikuz, G. C. Junkel-Vives, T. Caillaud, Joseph Abdallah, P. A. Loboda, I. A. Litvinenko, A. I. Magunov, V. V. Popova, C. Bonte, A. Ya. Faenov, Fabien Dorchies, François Salin, I. Yu. Skobelev, G. V. Baidin, F. Blasco, C. Stenz, BIOVERT (BIOVERT), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Laboratoire pour l'utilisation des lasers intenses (LULI), Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), and Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)

Subjects
[PHYS]Physics [physics], Electron density, Argon, Materials science, Physics and Astronomy (miscellaneous), chemistry.chemical_element, Pulse duration, Plasma, Laser, 7. Clean energy, 01 natural sciences, 010305 fluids & plasmas, Ion, law.invention, chemistry, law, 0103 physical sciences, Electron temperature, Emission spectrum, Atomic physics, 010306 general physics, ComputingMilieux_MISCELLANEOUS
Abstract

Line emission spectrum of a laser plasma produced in an argon cluster jet target was measured on the n1P1−11S0 (n=5–9) transitions of the helium-like Ar XVII ion for a pulse duration varying from 45 fs to 1.1 ps and a constant fluence of ∼105 J/cm2. The independent modeling of the relative intensities of the transitions from the n=5,..., 10 levels, as well as of the 21P1− 12S0 and 23P1−12S0 lines and dielectronic satellites indicates that the electron temperature is anomalously low and that the electron density in emitting plasma increases with shortening the laser pulse. The excitation from the ground state by a small fraction of hot electrons is expected to be the main channel of populating the Ar XVII levels.

Published
2001

16. Fundus changes in patients with the mitochondrial DNA point mutation at position 3243

Author

C, Bonte, A, Leys, G, Matthijs, and L, Missotten

Subjects
Adult, Macular Degeneration, Mitochondrial Encephalomyopathies, Humans, Point Mutation, Female, Middle Aged, DNA, Mitochondrial
Abstract

The A3243G transition in the mitochondrial DNA is commonly associated with the syndrome of mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS). Previously, atypical pigmentary retinopathy has been described in patients with this syndrome and in patients with other phenotypes of the same mitochondrial defect. Maternally inherited diabetes mellitus and deafness has been recognized as a distinct clinical presentation of the mitochondrial point mutation at position 3243, and recently a pattern dystrophy has been identified as a characteristic ocular abnormality in these patients. The finding of a macular pattern dystrophy in patients with diabetes should therefore lead to screening for this aberrant mitochondrial genome.

Published
1996

17. Weaning practices in phenylketonuria vary between health professionals in Europe

Author

A. Pinto, S. Adams, K. Ahring, H. Allen, M.F. Almeida, D. Garcia-Arenas, N. Arslan, M. Assoun, Y. Atik Altınok, D. Barrio-Carreras, A. Belanger Quintana, S.M. Bernabei, C. Bontemps, F. Boyle, G. Bruni, M. Bueno-Delgado, G. Caine, R. Carvalho, A. Chrobot, K. Chyż, B. Cochrane, C. Correia, K. Corthouts, A. Daly, S. De Leo, A. Desloovere, A. De Meyer, A. De Theux, B. Didycz, M.E. Dijsselhof, K. Dokoupil, J. Drabik, C. Dunlop, W. Eberle-Pelloth, K. Eftring, J. Ekengren, I. Errekalde, S. Evans, A. Foucart, L. Fokkema, L. François, M. French, E. Forssell, C. Gingell, C. Gonçalves, H. Gökmen Özel, A. Grimsley, G. Gugelmo, E. Gyüre, C. Heller, R. Hensler, I. Jardim, C. Joost, M. Jörg-Streller, C. Jouault, A. Jung, M. Kanthe, N. Koç, I.L. Kok, T. Kozanoğlu, B. Kumru, F. Lang, K. Lang, I. Liegeois, A. Liguori, R. Lilje, O. Ļubina, P. Manta-Vogli, D. Mayr, C. Meneses, C. Newby, U. Meyer, S. Mexia, C. Nicol, U. Och, S.M. Olivas, C. Pedrón-Giner, R. Pereira, K. Plutowska-Hoffmann, J. Purves, A. Re Dionigi, K. Reinson, M. Robert, L. Robertson, J.C. Rocha, C. Rohde, S. Rosenbaum-Fabian, A. Rossi, M. Ruiz, J. Saligova, A. Gutiérrez-Sánchez, A. Schlune, K. Schulpis, J. Serrano-Nieto, A. Skarpalezou, R. Skeath, A. Slabbert, K. Straczek, M. Giżewska, A. Terry, R. Thom, A. Tooke, J. Tuokkola, E. van Dam, T.A.M. van den Hurk, E.M.C. van der Ploeg, K. Vande Kerckhove, M. Van Driessche, A.M.J. van Wegberg, K. van Wyk, C. Vasconcelos, V. Velez García, J. Wildgoose, T. Winkler, J. Żółkowska, J. Zuvadelli, and A. MacDonald

Subjects
Medicine (General), R5-920, Biology (General), QH301-705.5
Abstract

Background: In phenylketonuria (PKU), weaning is considered more challenging when compared to feeding healthy infants. The primary aim of weaning is to gradually replace natural protein from breast milk or standard infant formula with solids containing equivalent phenylalanine (Phe). In addition, a Phe-free second stage L-amino acid supplement is usually recommended from around 6 months to replace Phe-free infant formula. Our aim was to assess different weaning approaches used by health professionals across Europe. Methods: A cross sectional questionnaire (survey monkey®) composed of 31 multiple and single choice questions was sent to European colleagues caring for inherited metabolic disorders (IMD). Centres were grouped into geographical regions for analysis. Results: Weaning started at 17–26 weeks in 85% (n = 81/95) of centres, >26 weeks in 12% (n = 11/95) and 26 weeks. First solids were mainly low Phe vegetables (59%, n = 56/95) and fruit (34%, n = 32/95).A Phe exchange system to allocate dietary Phe was used by 52% (n = 49/95) of centres predominantly from Northern and Southern Europe and 48% (n = 46/95) calculated most Phe containing food sources (all centres in Eastern Europe and the majority from Germany and Austria). Some centres used a combination of both methods.A second stage Phe-free L-amino acid supplement containing a higher protein equivalent was introduced by 41% (n = 39/95) of centres at infant age 26–36 weeks (mainly from Germany, Austria, Northern and Eastern Europe) and 37% (n = 35/95) at infant age > 1y mainly from Southern Europe. 53% (n = 50/95) of centres recommended a second stage Phe-free L-amino acid supplement in a spoonable or semi-solid form. Conclusions: Weaning strategies vary throughout European PKU centres. There is evidence to suggest that different infant weaning strategies may influence longer term adherence to the PKU diet or acceptance of Phe-free L-amino acid supplements; rendering prospective long-term studies important. It is essential to identify an effective weaning strategy that reduces caregiver burden but is associated with acceptable dietary adherence and optimal infant feeding development. Keywords: Weaning, Infant, Phenylketonuria, Phenylalanine, Phe-free infant formula

Published
2019
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18. Cleaning up the Geulhaven at Rotterdam

Author

S. J. B. C. Bonte and J. H. Volbeda

Subjects
Dredging, Backhoe loader, law, Environmental engineering, Environmental science, Turbidity, law.invention, Sand fraction
Abstract

The dredging treatment and storage of polluted soil is a great problem in the Netherlands as well as elsewhere. Dredging itself is hardly a problem. Much research has been done to find adapted ways of dredging in order not to pollute the waterbody while dredging and to prevent spreading of polluted dredged material to neighbouring unpolluted area’s. The anti-turbidity screen and the closed backhoe bucket are examples of this. Results of relevant measurements about turbidity caused by dredging have been publicized already. 1) Complete cleaning of larger volumes of dredged material has as yet not been practiced in the Netherlands in view of the immense cost involved.

Published
1990
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19. Sanierung des Geulhaven in Rotterdam

Author

S. J. B. C. Bonte and J. H. Volbeda

Abstract

Raumung und Lagerung von kontaminiertem Boden ist in den Niederlanden ebenso wie anderswo ein groses Problem. Das Raumen an sich ist eigentlich einfach. Es wurden umfangreiche Forschungsprogramme durchgefuhrt, um Spezialraum-methoden zu finden, bei denen das Wasser uber dem Schlamm beim Raumen nicht verschmutzt wird, und so zu verhindern, das das verschmutzte geraumte Material in benachbarte, saubere Zonen gelangt. Beispiele hierfur sind die Trubungsschutzvorrichtung und die geschlossene Baggerschaufel. Entsprechende Mesergebnisse uber die beim Raumen verursachte Wasserturbulenz wurden bereits veroffentlicht (1). Die vollkommene Massensanierung von geraumtem Material wurde in Anbetracht der enormen Kosten in den Niederlanden noch nicht durchgefuhrt.

Published
1990
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20. Early feeding practices in infants with phenylketonuria across Europe

Author

A. Pinto, S. Adams, K. Ahring, H. Allen, M.F. Almeida, D. Garcia-Arenas, N. Arslan, M. Assoun, Y. Atik Altınok, D. Barrio-Carreras, A. Belanger Quintana, S.M. Bernabei, C. Bontemps, F. Boyle, G. Bruni, M. Bueno-Delgado, G. Caine, R. Carvalho, A. Chrobot, K. Chyż, B. Cochrane, C. Correia, K. Corthouts, A. Daly, S. De Leo, A. Desloovere, A. De Meyer, A. De Theux, B. Didycz, M.E. Dijsselhof, K. Dokoupil, J. Drabik, C. Dunlop, W. Eberle-Pelloth, K. Eftring, J. Ekengren, I. Errekalde, S. Evans, A. Foucart, L. Fokkema, L. François, M. French, E. Forssell, C. Gingell, C. Gonçalves, H. Gökmen Özel, A. Grimsley, G. Gugelmo, E. Gyüre, C. Heller, R. Hensler, I. Jardim, C. Joost, M. Jörg-Streller, C. Jouault, A. Jung, M. Kanthe, N. Koç, I.L. Kok, T. Kozanoğlu, B. Kumru, F. Lang, K. Lang, I. Liegeois, A. Liguori, R. Lilje, O. Ļubina, P. Manta-Vogli, D. Mayr, C. Meneses, C. Newby, U. Meyer, S. Mexia, C. Nicol, U. Och, S.M. Olivas, C. Pedrón-Giner, R. Pereira, K. Plutowska-Hoffmann, J. Purves, A. Re Dionigi, K. Reinson, M. Robert, L. Robertson, J.C. Rocha, C. Rohde, S. Rosenbaum-Fabian, A. Rossi, M. Ruiz, J. Saligova, A. Gutiérrez-Sánchez, A. Schlune, K. Schulpis, J. Serrano-Nieto, A. Skarpalezou, R. Skeath, A. Slabbert, K. Straczek, M. Giżewska, A. Terry, R. Thom, A. Tooke, J. Tuokkola, E. van Dam, T.A.M. van den Hurk, E.M.C. van der Ploeg, K. Vande Kerckhove, M. Van Driessche, A.M.J. van Wegberg, K. van Wyk, C. Vasconcelos, V. Velez García, J. Wildgoose, T. Winkler, J. Żółkowska, J. Zuvadelli, and A. MacDonald

Subjects
Medicine (General), R5-920, Biology (General), QH301-705.5
Abstract

Background: In infants with phenylketonuria (PKU), dietary management is based on lowering and titrating phenylalanine (Phe) intake from breast milk or standard infant formula in combination with a Phe-free infant formula in order to maintain blood Phe levels within target range. Professionals use different methods to feed infants with PKU and our survey aimed to document practices across Europe. Methods: We sent a cross sectional, survey monkey® questionnaire to European health professionals working in IMD. It contained 31 open and multiple-choice questions. The results were analysed according to different geographical regions. Results: Ninety-five centres from 21 countries responded. Over 60% of centres commenced diet in infants by age 10 days, with 58% of centres implementing newborn screening by day 3 post birth. At diagnosis, infant hospital admission occurred in 61% of metabolic centres, mainly in Eastern, Western and Southern Europe. Breastfeeding fell sharply following diagnosis with only 30% of women still breast feeding at 6 months.53% of centres gave pre-measured Phe-free infant formula before each breast feed and 23% alternated breast feeds with Phe-free infant formula. With standard infant formula feeds, measured amounts were followed by Phe-free infant formula to satiety in 37% of centres (n = 35/95), whereas 44% (n = 42/95) advised mixing both formulas together. Weaning commenced between 17 and 26 weeks in 85% centres, ≥26 weeks in 12% and

Published
2018
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21. [Fronto-nasal dysplasia (apropos of 4 cases)]

Author

G, Fontaine, R, Walbaum, B, Poupard, C, Bonte, P, Dhellemmes, E, Maquet, H, Ythier, and C, Stevenard

Subjects
Cleft Palate, Male, Jaw Abnormalities, Child, Preschool, Humans, Abnormalities, Multiple, Female, Forehead, Syndrome, Nose, Child, Lip
Abstract

Four cases of frontonasal dysplasia are reported in two boys and two girls. Clinical diagnosis was made at 16 months in one case and sooner in 3 cases (1 month-3 1/2 months) in presence of following features: severe hypertelorism (4/4), paramedian lip and palate cleft (3/4), nose root broadering (4/4), bifid or cleft nose tip (3/4), window's peak (3/4) mediofrontal swelling (4/4), cranium bifidum occultum (2/4). Many abnormalities were associated: conduction deafness (1/4), goldenhar syndrome (1/4), GH deficiency (1/4), etc... In three cases when cerebral investigation was possible, it was pointed out: corpus callosum agenesis (3/3), hydrocephalus (3/3), Dandy-Walker cyst (2/3). Caryotype is normal in whole cases which are sporadic. Two children are dead. The two alive remaining have severe mental impairment.

Published
1983

23. [Acute spinal amyotrophy in toxoplasmosis]

Author

F, Dubois, H, Petit, O, Godefroy, C, Bonte, and J D, Guieu

Subjects
Adult, Male, Muscular Atrophy, Spinal, Acute Disease, Trimethoprim, Sulfamethoxazole Drug Combination, Humans, Toxoplasmosis
Abstract

A 19 year-old man developed an acute syndrome of the anterior horn of cervical spinal cord during a primo-infection with toxoplasma. The neurological syndrome was completely regressive after treatment with 1 600 mg/day of trimethoprim-sulfamethoxazole for three months.

Published
1989

24. A field study of the validity of static paper sampling in fluoride pollution surveys

Author

J. Bonte, J. Alary, P. Bourbon, C. Bonte, C. Balsa, Institut francilien recherche, innovation et société (IFRIS), Institut National de la Recherche Agronomique (INRA)-École des hautes études en sciences sociales (EHESS)-OST-Université Paris-Est Marne-la-Vallée (UPEM)-Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.)-ESIEE Paris-Centre National de la Recherche Scientifique (CNRS), and Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.)-Institut National de la Recherche Agronomique (INRA)-École des hautes études en sciences sociales (EHESS)-OST-Université Paris-Est Marne-la-Vallée (UPEM)-ESIEE Paris-Centre National de la Recherche Scientifique (CNRS)

Subjects
Pollution, Environmental Engineering, Field (physics), Accurate estimation, media_common.quotation_subject, [SDV]Life Sciences [q-bio], Mineralogy, Cattle Diseases, Soil science, Poaceae, chemistry.chemical_compound, Fluorides, Methods, Environmental Chemistry, Animals, Soil Pollutants, Waste Management and Disposal, ComputingMilieux_MISCELLANEOUS, media_common, Air Pollutants, fungi, Sampling (statistics), Particulates, chemistry, Evaluation Studies as Topic, Cattle, Environmental Pollutants, Seasons, Fluoride, Fluoride Poisoning
Abstract

A field study of fluoride pollution and of its consequences was made over a period of five years in the vicinity of an alumina reduction plant. This study, based upon the use of a static soda impregnated paper sampler, shows that the results obtained are in good agreement with the atmospheric fluoride concentrations obtained with dynamic samplers, especially when fluoride is present in gaseous form (HF). The results suggest that vertically mounted paper samplers are less sensitive to the collection of particulate fluorides. Collection rate is strongly influenced and increases with speed. If this parameter is known, an accurate estimation of the absolute atmospheric concentration is possible; the values shown by this technique are in good correlation with the value (annual mean) of pasture fluoride content. As a correlation exists between pasture fluoride content and the symptoms shown by cattle, the static filter samplers can predict disease in the case of slow chronic fluorosis. The field study agrees with earlier laboratory experiments and shows the validity of these simple and inexpensive types of exposure methods.

Published
1981

25. [A case of liposarcoma of the mediastinum]

Author

A, Briccoli, M, Beghi, M, Bertolani, and C, Bonte

Subjects
Male, Humans, Liposarcoma, Middle Aged, Tomography, X-Ray Computed, Mediastinal Neoplasms
Published
1985

31. [Tuberculosis in BCG vaccinated children]

Author

B, Gaudier and C, Bonte

Subjects
Male, Adolescent, Child, Preschool, BCG Vaccine, Hypersensitivity, Immunity, Humans, Infant, Tuberculosis, Female, Child
Published
1967

36. [Hypervitaminosis D in children. 3 cases]

Author

B, Gaudier, C, Ponté, J P, Nuyts, C, Bonte, P, Ryckewaert, and A, Lacombe

Subjects
Male, Child, Preschool, Infant, Newborn, Humans, Infant, Female, Vitamin D, Rickets
Published
1969

37. [Neonatal listeriosis: 5 cases]

Author

C, Ponté, C, Bonte, J P, Nuyts, P, Ryckewaert, L, Ryckewaert, B, Gosselin, A P, Blanc-Gabin, and C, Duquennoy

Subjects
Male, Infant, Newborn, Humans, Listeriosis, Infant, Premature, Diseases
Published
1969

47. [Aberrant sub-clavicular arteries in children (20 cases)]

Author

C, Dupuis, C, Ponte, J, Remy, C, Bonte, J P, Nuyts, J P, Farriaux, and E, Maillard

Subjects
Heart Defects, Congenital, Male, Child, Preschool, Age Factors, Angiography, Infant, Newborn, Subclavian Artery, Humans, Infant, Abnormalities, Multiple, Female, Child, Aortic Coarctation
Published
1970

48. [Total infradiaphragmatic, abnormal pulmonary venous return]

Author

C, Dupuis, H, Ducoulombier, P, Ryckewaert, P, Lequien, C, Bonte, and B, Leuridan

Subjects
Cyanosis, Heart Defects, Congenital, Male, Pulmonary Veins, Angiocardiography, Diaphragm, Angiography, Infant, Newborn, Humans, Heart Arrest
Published
1969

50. [Radioimmunological determination of plasmatic growth hormone in growth delays. Results recorded in 43 cases after stimulations with insulin and arginine]

Author

C, Ponté, P, Franchimont, B, Gaudier, J P, Nuyts, P, Ryckewaert, B, Deconinck, C, Bonte, and P, Debruxelles

Subjects
Male, Adolescent, Radioimmunoassay, Growth, Arginine, Body Height, Hypopituitarism, Hypothyroidism, Age Determination by Skeleton, Child, Preschool, Growth Hormone, Humans, Insulin, Female, Affective Symptoms, Child, Growth Disorders
Published
1970

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