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44 results on '"C Maio"'

1. Mental nerve paresthesia due to periapical pathology

Author: F. Di Francesco, S. Ferrara, C. Maio, G. De Marco, P. Sammartino, M. Menditti, D. Menditti1, L. Ramaglia, Di Francesco, F., Ferrara, S., Maio, C., De Marco, G., Sammartino, P., Menditti, M., Menditti1, D., and Ramaglia, L.
Published: 2019

2. Prevalence of Abdominal Aortic Aneurysms in the General Population and in Subgroups at High Cardiovascular Risk in Italy. Results of the RoCAV Population Based Study

Author: Francesco Gianfagna, Giovanni Veronesi, Matteo Tozzi, Antonino Tarallo, Rossana Borchini, Marco M. Ferrario, Lorenza Bertù, Andrea Montonati, Patrizio Castelli, Lorenzo Mara, Marco Franchin, Alessandro Angrisano, Marco Tadiello, Luca M. Quarti, Ilaria Tagliabue, Elena Buscarini, Valeria Farioli, Girolamo Sala, Sonia Agrusti, Alessandro Colombo, Stefania Ferraro, Nicola Rivolta, Gabriele Piffaretti, Marco Conti, Ramona C. Maio, Ursula Andreotta, Martina Ruspa, Laura Turetta, Tiziana Abate, Simona Rossi, Mariapia Ghiringhelli, Federica Quadrini, Nadia Facchinetti, Oriana Dashi, Silvia Mombelli, Davide Mazzoleni, Maria P. Martignoni, Gabriele Caravati, and Giancarlo De Luca
Subjects: Male, medicine.medical_specialty, Epidemiology, Population, Myocardial Infarction, 030204 cardiovascular system & hematology, 030230 surgery, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, medicine, Prevalence, Humans, Myocardial infarction, education, Stroke, Vascular diseases, Mass screening, Aged, Ultrasonography, Risk assessment, education.field_of_study, business.industry, Smoking, Middle Aged, medicine.disease, Abdominal aortic aneurysm, Cross-Sectional Studies, Cardiovascular diseases, Surgery, Cardiology and Cardiovascular Medicine, Italy, Population study, Female, business, Aortic Aneurysm, Abdominal
Abstract: Objectives Prevalence data on abdominal aortic aneurysm (AAA) in women, subjects younger than 65 years and in subgroups carrying specific risk factors are scarce. AAA prevalence was evaluated in an Italian population including women and younger subjects, stratifying for the presence of cardiovascular disease (CVD) risk factors and CVD risk score. Materials and methods A population based cross-sectional study was conducted between 2013 and 2016. Men aged 50–75 and women aged 60–75 years, resident in the city of Varese (northern Italy), were randomly selected from the civil registry. A vascular surgeon performed an abdominal aortic ultrasound scan at four sites using the leading edge to leading edge method. CVD risk score was computed using the ESC-SCORE algorithm. The age and gender specific prevalence was estimated, stratifying by the presence of CVD and cardiovascular risk factors. Results Among the 3755 subjects with a valid ultrasound measurement, 63 subjects with an AAA were identified (5 referred for surgical intervention), among whom 34 were not previously known (30 men 1.3%, 95% CI 0.9–1.8; 4 women 0.3%, 95% CI 0.1–0.8). Considering age classes in men only, the highest prevalence of screen detected AAA was found in subjects aged 65–70 (1.2%; 95% CI 0.4–2.5) and 70–75 (2.5%; 95% CI 1.4–4.0) years. Among 65–75 year old men, the highest AAA prevalence was found in subjects with a previous myocardial infarction (MI 4.9%, 95% CI 2.0–9.9) and in ever-smokers reporting more than 15 pack years of smoking (4.1%, 95% CI 2.5–6.3). Among the younger subjects, those having an ESC-SCORE higher than 5% or a previous CVD (MI or stroke) showed a prevalence of 1.4% (95% CI 0.3–4.2; prevalence including subaneurysms 6.7%, 95% CI 3.7–11.0%). Conclusions In the study population, both a general screening program in 65–75 year old men and an approach targeted to subgroups at higher risk merit evaluation in a cost-effectiveness study. In 50–64 year old men, strategies for population selection should consider CVD risk stratification tools.
Published: 2018

3. The potential role of in vivo optical coherence tomography for evaluating oral soft tissue: A systematic review

Author: Enrica Gentile, C Maio, Antonio Romano, Alberta Lucchese, Luigi Laino, Gentile, Enrica, Maio, Claudio, Romano, Antonio, Laino, Luigi, and Lucchese, Alberta
Subjects: 0301 basic medicine, Isi web of science, Cancer Research, medicine.medical_specialty, medical database, Population, Cochrane Library, Oral cavity, 01 natural sciences, Pathology and Forensic Medicine, 010309 optics, 03 medical and health sciences, Study Eligibility Criteria, Optical coherence tomography, In vivo, 0103 physical sciences, Medicine, Humans, Medical physics, education, education.field_of_study, Mouth, optical coherence tomography, medicine.diagnostic_test, oral mucosa, business.industry, Soft tissue, Surgery, in vivo, 030104 developmental biology, Otorhinolaryngology, Periodontics, Oral Surgery, business, Mouth Diseases, Tomography, Optical Coherence
Abstract: Background: The introduction of optical coherence tomography (OCT) in dentistry enabled the integration of already existing clinical and laboratory investigations in the study of the oral cavity. This systematic review presents an overview of the literature, to evaluate the usefulness of in vivo OCT for diagnosing oral soft tissues lesions, to compare the OCT results with traditional histology, and to identify limitations in prior studies so as to improve OCT applications. Methods: We performed a review of the literature using different search engines (PubMed, ISI Web of Science, and the Cochrane Library) employing MeSH terms such as “optical coherence tomography” and “OCT” in conjunction with other terms. We utilized the Population, Intervention, Comparison, Outcomes, and Study design (PICOS) method to define our study eligibility criteria. Results: Initial results were 3155. In conclusion, there were only 27 studies which met our selection criteria. We decided to allocate the 27 selected items into three groups: healthy mucosa; benign, premalignant, and malignant lesions; and oral manifestations of systemic therapies or pathological conditions. Conclusions: Although the OCT is an easy-to-perform test and it offers an attractive diagnostic and monitoring prospect for soft tissues of the oral cavity, further studies are needed to complete the current knowledge of this imaging technique. Background: The introduction of optical coherence tomography (OCT) in dentistry enabled the integration of already existing clinical and laboratory investigations in the study of the oral cavity. This systematic review presents an overview of the literature, to evaluate the usefulness of in vivo OCT for diagnosing oral soft tissues lesions, to compare the OCT results with traditional histology, and to identify limitations in prior studies so as to improve OCT applications. Methods: We performed a review of the literature using different search engines (PubMed, ISI Web of Science, and the Cochrane Library) employing MeSH terms such as “optical coherence tomography” and “OCT” in conjunction with other terms. We utilized the Population, Intervention, Comparison, Outcomes, and Study design (PICOS) method to define our study eligibility criteria. Results: Initial results were 3155. In conclusion, there were only 27 studies which met our selection criteria. We decided to allocate the 27 selected items into three groups: healthy mucosa; benign, premalignant, and malignant lesions; and oral manifestations of systemic therapies or pathological conditions. Conclusions: Although the OCT is an easy-to-perform test and it offers an attractive diagnostic and monitoring prospect for soft tissues of the oral cavity, further studies are needed to complete the current knowledge of this imaging technique.
Published: 2017

4. The potential role of in vivo reflectance confocal microscopy for evaluating oral cavity lesions: a systematic review

Author: Rosario Serpico, C Maio, Alberta Lucchese, Enrica Gentile, Antonio Romano, Luigi Laino, Lucchese, Alberta, Gentile, Enrica, Romano, Antonio, Maio, Claudio, Laino, Luigi, and Serpico, Rosario
Subjects: Reflectance confocal microscopy, Cancer Research, Pathology, medicine.medical_specialty, Future studies, medical database, hard tissue, reflectance confocal microscopy, Oral cavity, Pathology and Forensic Medicine, Autoimmune Diseases, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, In vivo, Oral and maxillofacial pathology, Medicine, Humans, Mouth mucosa, Mouth neoplasm, Microscopy, Confocal, oral mucosa, business.industry, Mouth Mucosa, medicine.disease, Clinical Practice, in vivo, Otorhinolaryngology, 030220 oncology & carcinogenesis, Periodontics, Mouth Neoplasms, Oral Surgery, business, Mouth Diseases, Precancerous Conditions
Abstract: Background: Since the early 2000s, several studies have examined the application of reflectance confocal microscopy (RCM) to the oral cavity. This review gives an overview of the literature on reflectance confocal microscopy analysis of the oral cavity in vivo and identifies flaws in the studies, providing guidance to improve reflectance confocal microscopy applications and inform the design of future studies. Methods: The PubMed, ISI, Scopus, and Cochrane Library databases were searched for publications on RCM using the terms ‘reflectance confocal microscopy’ in combination with ‘mouth’ and other terms related to the topic of interest. Results: The search gave 617 results. Seventeen studies were included in our final analysis. We decided to organize the selected articles according to four topics: healthy mucosa, autoimmune diseases, cancer and precancerous lesions, and hard dental tissues. Conclusion: Although reflectance confocal microscopy is promising for diagnosing and monitoring oral pathology, it has shortcomings and there are still too few publications on this topic. Further studies are needed to increase the quantity and quality of the results, to translate research into clinical practice. Background: Since the early 2000s, several studies have examined the application of reflectance confocal microscopy (RCM) to the oral cavity. This review gives an overview of the literature on reflectance confocal microscopy analysis of the oral cavity in vivo and identifies flaws in the studies, providing guidance to improve reflectance confocal microscopy applications and inform the design of future studies. Methods: The PubMed, ISI, Scopus, and Cochrane Library databases were searched for publications on RCM using the terms âreflectance confocal microscopyâ in combination with âmouthâ and other terms related to the topic of interest. Results: The search gave 617 results. Seventeen studies were included in our final analysis. We decided to organize the selected articles according to four topics: healthy mucosa, autoimmune diseases, cancer and precancerous lesions, and hard dental tissues. Conclusion: Although reflectance confocal microscopy is promising for diagnosing and monitoring oral pathology, it has shortcomings and there are still too few publications on this topic. Further studies are needed to increase the quantity and quality of the results, to translate research into clinical practice.
Published: 2016

5. Closed Fuel Cycle Waste Treatment Strategy

Author: J. H. Westsik, Gary J. Sevigny, Denis M. Strachan, Steven M. Frank, E. D. Collins, Robert Thomas Jubin, James C. Marra, Josef Matyas, John D. Vienna, William L. Ebert, Brian J. Riley, Dirk Gombert, Tina M. Nenoff, V. C. Maio, Troy G. Garn, Jarrod V. Crum, R. Jones, Nick Soelberg, and Praveen K. Thallapally
Subjects: Waste treatment, Materials science, Waste management, Fuel cycle, Radioactive waste, Refuse-derived fuel, Spent nuclear fuel, High-level waste
Published: 2015
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6. Nivolumab in previously untreated melanoma without BRAF mutation

Author: Robert, C. Long, G.V. Brady, B. Dutriaux, C. Maio, M. Mortier, L. Hassel, J.C. Rutkowski, P. McNeil, C. Kalinka-Warzocha, E. Savage, K.J. Hernberg, M.M. Lebbé, C. Charles, J. Mihalcioiu, C. Chiarion-Sileni, V. Mauch, C. Cognetti, F. Arance, A. Schmidt, H. Schadendorf, D. Gogas, H. Lundgren-Eriksson, L. Horak, C. Sharkey, B. Waxman, I.M. Atkinson, V. Ascierto, P.A.
Abstract: BACKGROUND: Nivolumab was associated with higher rates of objective response than chemotherapy in a phase 3 study involving patients with ipilimumab-refractory metastatic melanoma. The use of nivolumab in previously untreated patients with advanced melanoma has not been tested in a phase 3 controlled study. METHODS: We randomly assigned 418 previously untreated patients who had metastatic melanoma without a BRAF mutation to receive nivolumab (at a dose of 3 mg per kilogram of body weight every 2 weeks and dacarbazine-matched placebo every 3 weeks) or dacarbazine (at a dose of 1000 mg per square meter of body-surface area every 3 weeks and nivolumab-matched placebo every 2 weeks). The primary end point was overall survival. RESULTS: At 1 year, the overall rate of survival was 72.9% (95% confidence interval [CI], 65.5 to 78.9) in the nivolumab group, as compared with 42.1% (95% CI, 33.0 to 50.9) in the dacarbazine group (hazard ratio for death, 0.42; 99.79% CI, 0.25 to 0.73; P
Published: 2015

7. A medicina de Nina Rodrigues: análise de uma trajetória científica

Author: Marcos C. Maio
Subjects: história da medicina, história da antropologia, história da ciência, medicina legal, Medicine, Public aspects of medicine, RA1-1270
Abstract: Uma das maneiras mais profícuas de se pesquisar a história da medicina brasileira na passagem do século XIX para o XX é a investigação da trajetória profissional de determinados médicos que tiveram posições de relevo no processo de mudanças que atingiu o campo médico à época. Neste sentido, este artigo tem por objetivo analisar a carreira acadêmico-profissional de Raimundo Nina Rodrigues, a partir da noção de campo científico de Pierre Bourdieu. Partindo do princípio de que o campo médico é um espaço de confrontos estruturalmente determinado pelos embates passados, onde os médicos buscam monopolizar a autoridade/competência científica, considero que o perfil médico de Nina Rodrigues é um indicador preciso do processo de especialização e concorrência que se desenvolveu naquele momento.

8. The optical instrumentation of the ATLAS Tile Calorimeter

Author: Abdallah, J. Adragna, P. Alexa, C. Alves, R. Amaral, P. and Ananiev, A. Anderson, K. Andresen, X. Antonaki, A. and Batusov, V. Bednar, P. Bergeaas, E. Biscarat, C. Blanch, O. Blanchot, G. Bohm, C. Boldea, V. Bosi, F. Bosman, M. Bromberg, C. Budagov, J. Calvet, D. Cardeira, C. and Carli, T. Carvalho, J. Cascella, M. Castillo, M. V. and Costelo, J. Cavalli-Sforza, M. Cavasinni, V. Cerqueira, A. S. Clement, C. Cobal, M. Cogswell, F. Constantinescu, S. and Costanzo, D. Da Silva, P. David, M. Davidek, T. and Dawson, J. De, K. Del Prete, T. Diakov, E. Di Girolamo, B. Dita, S. Dolejsi, J. Dolezal, Z. Dotti, A. and Downing, R. Drake, G. Efthymiopoulos, I. Errede, D. and Errede, S. Farbin, A. Fassouliotis, D. Feng, E. Fenyuk, A. Ferdi, C. Ferreira, B. C. Ferrer, A. Flaminio, V. and Flix, J. Francavilla, P. Fullana, E. Garde, V. and Gellerstedt, K. Giakoumopoulou, V. Giangiobbe, V. and Gildemeister, O. Gilewsky, V. Giokaris, N. Gollub, N. and Gomes, A. Gonzalez, V. Gouveia, J. Grenier, P. Gris, P. and Guarino, V. Guicheney, C. Gupta, A. Hakobyan, H. and Haney, M. Hellman, S. Henriques, A. Higon, E. Hill, N. and Holmgren, S. Hruska, I. Hurwitz, M. Huston, J. and Plante, I. Jen-La Jon-And, K. Junk, T. Karyukhin, A. and Khubua, J. Klereborn, J. Konstantinov, V. Kopikov, S. and Korolkov, I. Krivkova, P. Kulchitsky, Y. Kurochkin, Yu and Kuzhir, P. Lapin, V. LeCompte, T. Lefevre, R. Leitner, R. Li, J. Liablin, M. Lokajicek, M. Lomakin, Y. and Lourtie, P. Lovas, L. Lupi, A. Maidantchik, C. Maio, A. and Maliukov, S. Manousakis, A. Marques, C. Marroquim, F. and Martin, F. Mazzoni, E. Merritt, F. Miagkov, A. and Miller, R. Minashvili, I. Miralles, L. Montarou, G. and Nemecek, S. Nessi, M. Nikitine, I. Nodulman, L. and Norniella, O. Onofre, A. Oreglia, M. Palan, B. Pallin, D. Pantea, D. Pereira, A. Pilcher, J. Pina, J. and Pinhao, J. Pod, E. Podlyski, F. Portell, X. Poveda, J. and Pribyl, L. Price, E. Proudfoot, J. Ramalho, M. and Ramstedt, M. Raposeiro, L. Reis, J. Richards, R. Roda, C. Romanov, V. Rosnet, P. Roy, P. Ruiz, A. and Rumiantsau, V. Russakovich, N. Da Costa, J. Sa Salto, O. and Salvachua, B. Sanchis, E. Sanders, H. Santoni, C. and Santos, J. Saraiva, J. G. Sarri, F. Says, L. -P. and Schlager, G. Schlereth, J. Seixas, J. M. Sellden, B. and Shalanda, N. Shevtsov, P. Shochet, M. Silva, J. and Simaitis, V. Simonyan, M. Sissakian, A. Sjoelin, J. and Solans, C. Solodkov, A. Solovianov, O. Sosebee, M. and Spano, F. Speckmeyer, P. Stanek, R. Starchenko, E. and Starovoitov, P. Suk, M. Sykora, I. Tang, F. Tas, P. and Teuscher, R. Tischenko, M. Tokar, S. Topilin, N. Torres, J. Underwood, D. Usai, G. Valero, A. Valkar, S. and Valls, J. A. Vartapetian, A. Vazeille, F. Vellidis, C. and Ventura, F. Vichou, I. Vivarelli, I. Volpi, M. White, A. and Zaitsev, A. Zaytsev, Yu Zenin, A. Zenis, T. Zenonos, Z. Zenz, S. Zilka, B. ATLAS Tile Calorimeter Community
Subjects: Physics::Instrumentation and Detectors, High Energy Physics::Experiment
Abstract: The Tile Calorimeter, covering the central region of the ATLAS experiment up to pseudorapidities of +/-1.7, is a sampling device built with scintillating tiles that alternate with iron plates. The light is collected in wave-length shifting (WLS) fibers and is read out with photomultipliers. In the characteristic geometry of this calorimeter the tiles lie in planes perpendicular to the beams, resulting in a very simple and modular mechanical and optical layout. This paper focuses on the procedures applied in the optical instrumentation of the calorimeter, which involved the assembly of about 460,000 scintillator tiles and 550,000 WLS fibers. The outcome is a hadronic calorimeter that meets the ATLAS performance requirements, as shown in this paper.
Published: 2013

9. Mechanical construction and installation of the ATLAS tile calorimeter

Author: Abdallah, J. Adragna, P. Alexa, C. Alves, R. Amaral, P. Ananiev, A. Anderson, K. Andresen, X. Antonaki, A. Batusov, V. Bednar, P. Behrens, A. Bergeaas, E. Biscarat, C. Blanch, O. Blanchot, G. Blocki, J. Bohm, C. Boldea, V. Bosi, F. Bosman, M. Bromberg, C. Brunel, B. Budagov, J. Calderón, D. Calvet, D. Cardeira, C. Carli, T. Carvalho, J. Cascella, M. Castillo, M.V. Costello, J. Cavalli-Sforza, M. Cavasinni, V. Cerqueira, A.S. Clement, C. Cobal, M. Cogswell, F. Constantinescu, S. Costanzo, D. Da Silva, P. David, M. Davidek, T. Dawson, J. De, K. Del Prete, T. Di Girolamo, B. Dita, S. Dolejsi, J. Dolezal, Z. Dotti, A. Downing, R. Drake, G. Efthymiopoulos, I. Errede, D. Errede, S. Farbin, A. Fassouliotis, D. Feng, E. Fenyuk, A. Ferdi, C. Ferreira, B.C. Ferrer, A. Ferrer, J. Flaminio, V. Flix, J. Francavilla, P. Fullana, E. Garde, V. Gayde, J.C. Gellerstedt, K. Giakoumopoulou, V. Giangiobbe, V. Gildemeister, O. Gilewsky, V. Giokaris, N. Gollub, N. Gomes, A. Gonzalez, V. Gouveia, J. Grenier, P. Gris, P. Grudzinski, J. Guarino, V. Guicheney, C. Gupta, A. Hakobyan, H. Haney, M. Hellman, S. Henriques, A. Higon, E. Hill, N. Holmgren, S. Hruska, I. Hurwitz, M. Huston, J. Jen-La Plante, I. Jon-And, K. Junk, T. Karyukhin, A. Khubua, J. Klereborn, J. Kopikov, S. Korolkov, I. Krivkova, P. Kulchitsky, Y. Kurochkin, Y. Kuzhir, P. Lapin, V. Lasseur, C. Lecompte, T. Lefevre, R. Leitner, R. Li, J. Lyablin, M. Lim, H. Lokajicek, M. Lomakin, Y. Lourtie, P. Lovas, L. Lupi, A. Maidantchik, C. Maio, A. Maliukov, S. Manousakis, A. Marques, C. Marroquim, F. Martin, F. Mazzoni, E. Mergelkuhl, D. Merritt, F. Miagkov, A. Miller, R. Minashvili, I. Miralles, L. Montarou, G. Nemecek, S. Nessi, M. Nikitine, I. Nodulman, L. Norniella, O. Nyman, T. Onofre, A. Oreglia, M. Palan, B. Pallin, D. Pantea, D. Pereira, A. Pilcher, J. Pina, J. Pinhão, J. Pod, E. Podlyski, F. Portell, X. Poveda, J. Pribyl, L. Price, L.E. Proudfoot, J. Ramalho, M. Ramstedt, M. Raposeiro, L. Reis, J. Richards, R. Roda, C. Romanov, V. Rose-Dulcina, L. Rosnet, P. Roy, P. Ruiz, A. Rumiantsau, V. Russakovich, N. Sa Da Costa, J. Salto, O. Salvachua, B. Sanchis, E. Sanders, H. Santoni, C. Santos, J. Saraiva, J.G. Sarri, F. -P Says, L. Schlager, G. Schlereth, J. Seixas, J.M. Selldèn, B. Shalanda, N. Shchelchkov, A. Shevtsov, P. Shochet, M. Silva, J. Simaitis, V. Simonyan, M. Sissakian, A. Sjoelin, J. Skrzecz, F. Solans, C. Solodkov, A. Solovianov, O. Sorokina, J. Sosebee, M. Spano, F. Speckmeyer, P. Stanek, R. Starchenko, E. Starovoitov, P. Suk, M. Sykora, I. Tang, F. Tas, P. Teuscher, R. Tokar, S. Topilin, N. Torres, J. Underwood, D. Usai, G. Utkin, V. Valero, A. Valkar, S. Valls, J.A. Vartapetian, A. Vazeille, F. Vellidis, C. Ventura, F. Vichou, I. Vivarelli, I. Volpi, M. White, A. Wood, K. Zaitsev, A. Zenin, A. Zenis, T. Zenonos, Z. Zenz, S. Zilka, B.
Subjects: Physics::Instrumentation and Detectors, High Energy Physics::Experiment
Abstract: This paper summarises the mechanical construction and installation of the Tile Calorimeter for the ATLAS experiment at the Large Hadron Collider in CERN, Switzerland. The Tile Calorimeter is a sampling calorimeter using scintillator as the sensitive detector and steel as the absorber and covers the central region of the ATLAS experiment up to pseudorapidities ±1.7. The mechanical construction of the Tile Calorimeter occurred over a period of about 10 years beginning in 1995 with the completion of the Technical Design Report and ending in 2006 with the installation of the final module in the ATLAS cavern. During this period approximately 2600 metric tons of steel were transformed into a laminated structure to form the absorber of the sampling calorimeter. Following instrumentation and testing, which is described elsewhere, the modules were installed in the ATLAS cavern with a remarkable accuracy for a structure of this size and weight. © CERN 2013 for the benefit of the ATLAS collaboration.
Published: 2013

10. Different behavioral effects of haloperidol, clozapine and thioridazine in a concurrent lever pressing and feeding procedure

Author: T Turski, M Champion, John D. Salamone, C Maio, Michael S. Cousins, and J Kovach
Subjects: Male, Time Factors, business.product_category, Sedation, Thioridazine, Pharmacology, law.invention, Rats, Sprague-Dawley, Operant conditioning chamber, law, medicine, Haloperidol, Animals, Clozapine, Lever, digestive, oral, and skin physiology, Antagonist, Feeding Behavior, Rats, Dopamine receptor, Conditioning, Operant, medicine.symptom, Psychology, business, Antipsychotic Agents, medicine.drug
Abstract: Rats were tested using a lever pressing/feeding procedure in which a preferred food (Bioserve pellets) was available by pressing a lever on a fixed ratio 5 schedule, but a less preferred food (lab chow) was also available concurrently in the operant chamber. The effects of repeated (14 day) injections of haloperidol, clozapine and thioridazine were compared. Haloperidol (0.05-0.15 mg/kg) significantly reduced lever pressing and increased chow intake throughout the drug treatment period. Injections of clozapine (2.0-6.0 mg/kg) suppressed lever pressing but failed to produce substantial increases in chow intake. In the haloperidol experiment there was a significant inverse correlation between lever pressing and chow intake, but in the clozapine experiment there was not. Regression analysis indicated that rats treated with the high dose of clozapine showed some tolerance to the suppression of lever pressing. Tests of sedation also were conducted before and after the instrumental behavior sessions. Haloperidol produced little or no sedative effect in the dose range tested. Clozapine produced substantial sedation during the first 10 days of administration, but this effect, like the suppression of lever pressing, showed signs of tolerance. Thioridazine (3.0-9.0 mg/kg) produced some effects that resembled haloperidol, and other effects, including sedation, that resembled clozapine. These studies indicate that haloperidol suppresses lever pressing for food at low doses that do not produce severe motivational or sedative effects that disrupt food intake. In contrast, it appears as though the suppression of lever pressing produced by clozapine stems from a sedative effect that also serves to set limits on chow intake. These results indicate that haloperidol and clozapine suppress lever pressing through different mechanisms.
Published: 1996
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11. A medicina de Nina Rodrigues: análise de uma trajetória científica Brazilian physician Nina Rodrigues: analysis of a scientific career

Author: Marcos C. Maio
Subjects: História da Ciência, History of Science, History of Anthropology, Medicina Legal, lcsh:Public aspects of medicine, lcsh:R, lcsh:Medicine, História da Medicina, História da Antropologia, History of Medicine, lcsh:RA1-1270, Legal Medicine
Abstract: Uma das maneiras mais profícuas de se pesquisar a história da medicina brasileira na passagem do século XIX para o XX é a investigação da trajetória profissional de determinados médicos que tiveram posições de relevo no processo de mudanças que atingiu o campo médico à época. Neste sentido, este artigo tem por objetivo analisar a carreira acadêmico-profissional de Raimundo Nina Rodrigues, a partir da noção de campo científico de Pierre Bourdieu. Partindo do princípio de que o campo médico é um espaço de confrontos estruturalmente determinado pelos embates passados, onde os médicos buscam monopolizar a autoridade/competência científica, considero que o perfil médico de Nina Rodrigues é um indicador preciso do processo de especialização e concorrência que se desenvolveu naquele momento.One of the most productive ways of investigating the history of Brazilian medical practice at the turn of this century is to focus on the fruitful and ambiguous careers of those physicians that played an important role in the changes affecting the medical field at that time. This paper aims at analyzing the scientific career of physician-anthropologist Raimundo Nina Rodrigues, taking as its conceptual basis Pierrre Bourdieu's notion of "scientific field ". The paper's point of departure is the notion that the medical field is a space of confrontation that is structurally determined by previous conflicts in which physicians try to monopolize claims to scientific authority and competence. Nina Rodrigues' medical profile appears in this context as a precise indicator of the process of specialization and competition that took place during that period.
Published: 1995

12. Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes

Author: Armando Stano, Morgane Gillard, Alexandra C. Maio-Liu, Evan A. Scott, Jeffrey A. Hubbell, and Melody A. Swartz
Subjects: Polymers, T-Lymphocytes, Priming (immunology), 02 engineering and technology, CD8-Positive T-Lymphocytes, Cross-Presentation, Mice, Drug Delivery Systems, Size, Copolymer, Cells, Cultured, 0303 health sciences, biology, Imidazoles, Cross-presentation, Self-assembly, 021001 nanoscience & nanotechnology, Interleukin-12, Innate Immunity, 3. Good health, Cell biology, Vivo, medicine.anatomical_structure, Mechanics of Materials, Aminoquinolines, 0210 nano-technology, Materials science, T cell, Biophysics, Bioengineering, Microparticles, Poly(Propylene Sulfide) Nanoparticles, Biomaterials, Immunomodulation, 03 medical and health sciences, Antigen, Gardiquimod, MHC class I, medicine, Animals, Vesicles, 030304 developmental biology, Mhc Class-I, Ph, Interleukin-6, Vaccine-Delivery, Dendritic cell, Dendritic Cells, Mice, Inbred C57BL, Immunology, Polymersome, Drug delivery, Ceramics and Composites, biology.protein
Abstract: While current subunit vaccines successfully induce humoral immune responses, a need exists for vaccine strategies to elicit strong cell-mediated immunity to address diseases such as cancer and chronic viral infection. Polymersomes are stable vesicles composed of self-assembling block copolymers with tunable degradation properties allowing delivery of both hydrophilic (within vesicle interior) or hydrophobic (within vesicle membrane) payload molecules. Here we apply oxidation-sensitive nanoscale polymersomes for both antigen and adjuvant delivery to dendritic cell (DC) endosomes. Calcein-loaded polymersomes were observed to release their payload initially in multiple DC endosomal compartments and subsequently within the cytosol. With either the Toll-like receptor agonists gardiquimod or R848 as payloads within the polymersomes, release resulted in DC activation, as indicated by induction of inflammatory cytokine expression and upregulation of DC maturation surface markers: for example, the ability of gardiquimod to induce IL-6 and IL-12 cytokine expression by DCs was enhanced 10-fold when loaded within polymersomes. With the model antigen ovalbumin as a payload, release resulted in CD8(+) T cell cross-priming by promoting protein antigen cross-presentation through MHC I, as indicated by activation of OT-I CD8(+) T cells. Our results demonstrate that oxidation-sensitive polymersomes can function as a vaccine delivery platform for inducing cell-mediated antigen-specific immune responses. (C) 2012 Elsevier Ltd. All rights reserved.
Published: 2012

13. The ATLAS Inner Detector commissioning and calibration

Author: The ATLAS Collaboration Aad, G. Abbott, B. Abdallah, J. Abdelalim, A.A. Abdesselam, A. Abdinov, O. Abi, B. Abolins, M. Abramowicz, H. Abreu, H. Acharya, B.S. Adams, D.L. Addy, T.N. Adelman, J. Adorisio, C. Adragna, P. Adye, T. Aefsky, S. Aguilar-Saavedra, J.A. Aharrouche, M. Ahlen, S.P. Ahles, F. Ahmad, A. Ahsan, M. Aielli, G. Akdogan, T. Åkesson, T.P.A. Akimoto, G. Akimov, A.V. Aktas, A. Alam, M.S. Alam, M.A. Albrand, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexander, G. Alexandre, G. Alexopoulos, T. Alhroob, M. Aliev, M. Alimonti, G. Alison, J. Aliyev, M. Allport, P.P. Allwood-Spiers, S.E. Almond, J. Aloisio, A. Alon, R. Alonso, A. Alviggi, M.G. Amako, K. Amelung, C. Amorim, A. Amorós, G. Amram, N. Anastopoulos, C. Andeen, T. Anders, C.F. Anderson, K.J. Andreazza, A. Andrei, V. Anduaga, X.S. Angerami, A. Anghinolfi, F. Anjos, N. Annovi, A. Antonaki, A. Antonelli, M. Antonelli, S. Antos, J. Antunovic, B. Anulli, F. Aoun, S. Arabidze, G. Aracena, I. Arai, Y. Arce, A.T.H. Archambault, J.P. Arfaoui, S. Arguin, J.-F. Argyropoulos, T. Arik, M. Armbruster, A.J. Arnaez, O. Arnault, C. Artamonov, A. Arutinov, D. Asai, M. Asai, S. Asfandiyarov, R. Ask, S. Åsman, B. Asner, D. Asquith, L. Assamagan, K. Astvatsatourov, A. Atoian, G. Auerbach, B. Augsten, K. Aurousseau, M. Austin, N. Avolio, G. Avramidou, R. Ay, C. Azuelos, G. Azuma, Y. Baak, M.A. Bach, A.M. Bachacou, H. Bachas, K. Backes, M. Badescu, E. Bagnaia, P. Bai, Y. Bain, T. Baines, J.T. Baker, O.K. Baker, M.D. Baker, S. Dos Pedrosa, F.B.S. Banas, E. Banerjee, P. Banerjee, S. Banfi, D. Bangert, A. Bansal, V. Baranov, S.P. Barashkou, A. Barber, T. Barberio, E.L. Barberis, D. Barbero, M. Bardin, D.Y. Barillari, T. Barisonzi, M. Barklow, T. Barlow, N. Barnett, B.M. Barnett, R.M. Baroncelli, A. Barr, A.J. Barreiro, F. Guimarães da Costa, J.B. Barrillon, P. Bartoldus, R. Bartsch, D. Bates, R.L. Batkova, L. Batley, J.R. Battaglia, A. Battistin, M. Bauer, F. Bawa, H.S. Bazalova, M. Beare, B. Beau, T. Beauchemin, P.H. Beccherle, R. Bechtle, P. Beck, G.A. Beck, H.P. Beckingham, M. Becks, K.H. Beddall, A.J. Beddall, A. Bednyakov, V.A. Bee, C. Begel, M. Harpaz, S.B. Behera, P.K. Beimforde, M. Belanger-Champagne, C. Bell, P.J. Bell, W.H. Bella, G. Bellagamba, L. Bellina, F. Bellomo, M. Belloni, A. Belotskiy, K. Beltramello, O. Ami, S.B. Benary, O. Benchekroun, D. Bendel, M. Benedict, B.H. Benekos, N. Benhammou, Y. Benjamin, D.P. Benoit, M. Bensinger, J.R. Benslama, K. Bentvelsen, S. Beretta, M. Berge, D. Kuutmann, E.B. Berger, N. Berghaus, F. Berglund, E. Beringer, J. Bernabéu, J. Bernat, P. Bernhard, R. Bernius, C. Berry, T. Bertin, A. Besana, M.I. Besson, N. Bethke, S. Bianchi, R.M. Bianco, M. Biebel, O. Biesiada, J. Biglietti, M. Bilokon, H. Bindi, M. Bingul, A. Bini, C. Biscarat, C. Bitenc, U. Black, K.M. Blair, R.E. Blanchard, J.-B. Blanchot, G. Blocker, C. Blondel, A. Blum, W. Blumenschein, U. Bobbink, G.J. Bocci, A. Boehler, M. Boek, J. Boelaert, N. Böser, S. Bogaerts, J.A. Bogouch, A. Bohm, C. Bohm, J. Boisvert, V. Bold, T. Boldea, V. Bondarenko, V.G. Bondioli, M. Boonekamp, M. Bordoni, S. Borer, C. Borisov, A. Borissov, G. Borjanovic, I. Borroni, S. Bos, K. Boscherini, D. Bosman, M. Boterenbrood, H. Bouchami, J. Boudreau, J. Bouhova-Thacker, E.V. Boulahouache, C. Bourdarios, C. Boveia, A. Boyd, J. Boyko, I.R. Bozovic-Jelisavcic, I. Bracinik, J. Braem, A. Branchini, P. Brandt, A. Brandt, G. Brandt, O. Bratzler, U. Brau, B. Brau, J.E. Braun, H.M. Brelier, B. Bremer, J. Brenner, R. Bressler, S. Britton, D. Brochu, F.M. Brock, I. Brock, R. Brodet, E. Bromberg, C. Brooijmans, G. Brooks, W.K. Brown, G. Bruckman de Renstrom, P.A. Bruncko, D. Bruneliere, R. Brunet, S. Bruni, A. Bruni, G. Bruschi, M. Bucci, F. Buchanan, J. Buchholz, P. Buckley, A.G. Budagov, I.A. Budick, B. Büscher, V. Bugge, L. Bulekov, O. Bunse, M. Buran, T. Burckhart, H. Burdin, S. Burgess, T. Burke, S. Busato, E. Bussey, P. Buszello, C.P. Butin, F. Butler, B. Butler, J.M. Buttar, C.M. 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Cheplakov, A. Chepurnov, V.F. Cherkaoui El Moursli, R. Tcherniatine, V. Chesneanu, D. Cheu, E. Cheung, S.L. Chevalier, L. Chevallier, F. Chiefari, G. Chikovani, L. Childers, J.T. Chilingarov, A. Chiodini, G. Chizhov, V. Choudalakis, G. Chouridou, S. Christidi, I.A. Christov, A. Chromek-Burckhart, D. Chu, M.L. Chudoba, J. Ciapetti, G. Ciftci, A.K. Ciftci, R. Cinca, D. Cindro, V. Ciobotaru, M.D. Ciocca, C. Ciocio, A. Cirilli, M. Clark, A. Clark, P.J. Cleland, W. Clemens, J.C. Clement, B. Clement, C. Coadou, Y. Cobal, M. Coccaro, A. Cochran, J. Coggeshall, J. Cogneras, E. Colijn, A.P. Collard, C. Collins, N.J. Collins-Tooth, C. Collot, J. Colon, G. Conde Muiño, P. Coniavitis, E. Conidi, M.C. Consonni, M. Constantinescu, S. Conta, C. Conventi, F. Cooke, M. Cooper, B.D. Cooper-Sarkar, A.M. Cooper-Smith, N.J. Copic, K. Cornelissen, T. Corradi, M. Corriveau, F. Corso-Radu, A. Cortes-Gonzalez, A. Cortiana, G. Costa, G. Costa, M.J. Costanzo, D. Costin, T. Côté, D. Torres, R.C. Courneyea, L. Cowan, G. Cowden, C. Cox, B.E. Cranmer, K. Cranshaw, J. Cristinziani, M. Crosetti, G. Crupi, R. Crépé-Renaudin, S. Almenar, C.C. Donszelmann, T.C. Curatolo, M. Curtis, C.J. Cwetanski, P. Czyczula, Z. D'Auria, S. D'Onofrio, M. D'Orazio, A. Da Via, C. Dabrowski, W. Dai, T. Dallapiccola, C. Dallison, S.J. Daly, C.H. Dam, M. Danielsson, H.O. Dannheim, D. Dao, V. Darbo, G. Darlea, G.L. Davey, W. Davidek, T. Davidson, N. Davidson, R. Davies, M. Davison, A.R. Dawson, I. Daya, R.K. De, K. de Asmundis, R. De Castro, S. De Faria Salgado, P.E.C. De Cecco, S. de Graat, J. De Groot, N. de Jong, P. De Mora, L. De Branco, M.O. De Pedis, D. De Salvo, A. De Sanctis, U. De Santo, A. De Vivie De Regie, J.B. Dean, S. Dedovich, D.V. Degenhardt, J. Dehchar, M. Del Papa, C. Del Peso, J. Del Prete, T. Dell'Acqua, A. Dell'Asta, L. Della Pietra, M. della Volpe, D. Delmastro, M. Delsart, P.A. Deluca, C. Demers, S. Demichev, M. Demirkoz, B. Deng, J. Deng, W. Denisov, S.P. Derkaoui, J.E. Derue, F. Dervan, P. Desch, K. Deviveiros, P.O. Dewhurst, A. DeWilde, B. Dhaliwal, S. Dhullipudi, R. Di Ciaccio, A. Di Ciaccio, L. Di Girolamo, A. Di Girolamo, B. Di Luise, S. Di Mattia, A. Di Nardo, R. Di Simone, A. Di Sipio, R. Diaz, M.A. Diblen, F. Diehl, E.B. Dietrich, J. Dietzsch, T.A. Diglio, S. Yagci, K.D. Dingfelder, J. Dionisi, C. Dita, P. Dita, S. Dittus, F. Djama, F. Djilkibaev, R. Djobava, T. do Vale, M.A.B. Do Wemans, A.V. Doan, T.K.O. Dobos, D. Dobson, E. Dobson, M. Doglioni, C. Doherty, T. Dolejsi, J. Dolenc, I. Dolezal, Z. Dolgoshein, B.A. Dohmae, T. Donega, M. Donini, J. Dopke, J. Doria, A. Dos Anjos, A. Dotti, A. Dova, M.T. Doxiadis, A. Doyle, A.T. Drasal, Z. Dris, M. Dubbert, J. Duchovni, E. Duckeck, G. Dudarev, A. Dudziak, F. Dührssen, M. Duflot, L. Dufour, M.-A. Dunford, M. Yildiz, H.D. Duxfield, R. Dwuznik, M. Düren, M. Ebenstein, W.L. Ebke, J. Eckweiler, S. Edmonds, K. Edwards, C.A. Egorov, K. Ehrenfeld, W. Ehrich, T. Eifert, T. Eigen, G. Einsweiler, K. Eisenhandler, E. Ekelof, T. El Kacimi, M. Ellert, M. Elles, S. Ellinghaus, F. Ellis, K. Ellis, N. Elmsheuser, J. Elsing, M. Emeliyanov, D. Engelmann, R. Engl, A. Epp, B. Eppig, A. Erdmann, J. Ereditato, A. Eriksson, D. Ermoline, I. Ernst, J. Ernst, M. Ernwein, J. Errede, D. Errede, S. Ertel, E. Escalier, M. Escobar, C. Curull, X.E. Esposito, B. Etienvre, A.I. Etzion, E. Evans, H. Fabbri, L. Fabre, C. Facius, K. Fakhrutdinov, R.M. Falciano, S. Fang, Y. Fanti, M. Farbin, A. Farilla, A. Farley, J. Farooque, T. Farrington, S.M. Farthouat, P. Fassnacht, P. Fassouliotis, D. Fatholahzadeh, B. Fayard, L. Fayette, F. Febbraro, R. Federic, P. Fedin, O.L. Fedorko, W. Feligioni, L. Felzmann, C.U. Feng, C. Feng, E.J. Fenyuk, A.B. Ferencei, J. Ferland, J. Fernandes, B. Fernando, W. Ferrag, S. Ferrando, J. Ferrara, V. Ferrari, A. Ferrari, P. Ferrari, R. Ferrer, A. Ferrer, M.L. Ferrere, D. Ferretti, C. Fiascaris, M. Fiedler, F. Filipčič, A. Filippas, A. Filthaut, F. Fincke-Keeler, M. Fiolhais, M.C.N. Fiorini, L. Firan, A. 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Zaitsev, A.M. Zajacova, Z. Zambrano, V. Zanello, L. Zaytsev, A. Zeitnitz, C. Zeller, M. Zemla, A. Zendler, C. Zenin, O. Zenis, T. Zenonos, Z. Zenz, S. Zerwas, D. della Porta, G.Z. Zhan, Z. Zhang, H. Zhang, J. Zhang, Q. Zhang, X. Zhao, L. Zhao, T. Zhao, Z. Zhemchugov, A. Zhong, J. Zhou, B. Zhou, N. Zhou, Y. Zhu, C.G. Zhu, H. Zhu, Y. Zhuang, X. Zhuravlov, V. Zimmermann, R. Zimmermann, S. Zimmermann, S. Ziolkowski, M. Živković, L. Zobernig, G. Zoccoli, A. zur Nedden, M. Zutshi, V.
Subjects: Physics::Instrumentation and Detectors
Abstract: The ATLAS Inner Detector is a composite tracking system consisting of silicon pixels, silicon strips and straw tubes in a 2 T magnetic field. Its installation was completed in August 2008 and the detector took part in data-taking with single LHC beams and cosmic rays. The initial detector operation, hardware commissioning and in-situ calibrations are described. Tracking performance has been measured with 7. 6 million cosmic-ray events, collected using a tracking trigger and reconstructed with modular pattern-recognition and fitting software. The intrinsic hit efficiency and tracking trigger efficiencies are close to 100%. Lorentz angle measurements for both electrons and holes, specific energy-loss calibration and transition radiation turn-on measurements have been performed. Different alignment techniques have been used to reconstruct the detector geometry. After the initial alignment, a transverse impact parameter resolution of 22. 1±0. 9 μm and a relative momentum resolution σp/p=(4. 83±0. 16)×10-4 GeV-1×pT have been measured for high momentum tracks. © 2010 CERN for the benefit of the ATLAS collaboration.
Published: 2010

14. Commissioning of the ATLAS Muon Spectrometer with cosmic rays

Author: The ATLAS Collaboration Aad, G. Abbott, B. Abdallah, J. Abdelalim, A.A. Abdesselam, A. Abdinov, O. Abi, B. Abolins, M. Abramowicz, H. Abreu, H. Acharya, B.S. Adams, D.L. Addy, T.N. Adelman, J. Adorisio, C. Adragna, P. Adye, T. Aefsky, S. Aguilar-Saavedra, J.A. Aharrouche, M. Ahlen, S.P. Ahles, F. Ahmad, A. Ahmed, H. Ahsan, M. Aielli, G. Akdogan, T. Åkesson, T.P.A. Akimoto, G. Akimov, A.V. Aktas, A. Alam, M.S. Alam, M.A. Albrand, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexander, G. Alexandre, G. Alexopoulos, T. Alhroob, M. Aliev, M. Alimonti, G. Alison, J. Aliyev, M. Allport, P.P. Allwood-Spiers, S.E. Almond, J. Aloisio, A. Alon, R. Alonso, A. Alviggi, M.G. Amako, K. Amelung, C. Amorim, A. Amorós, G. Amram, N. Anastopoulos, C. Andeen, T. Anders, C.F. Anderson, K.J. Andreazza, A. Andrei, V. Anduaga, X.S. Angerami, A. Anghinolfi, F. Anjos, N. Annovi, A. Antonaki, A. Antonelli, M. Antonelli, S. Antos, J. Antunovic, B. Anulli, F. Aoun, S. Arabidze, G. Aracena, I. Arai, Y. Arce, A.T.H. Archambault, J.P. Arfaoui, S. Arguin, J.-F. Argyropoulos, T. Arik, M. Armbruster, A.J. Arnaez, O. Arnault, C. Artamonov, A. Arutinov, D. Asai, M. Asai, S. Asfandiyarov, R. Ask, S. Åsman, B. Asner, D. Asquith, L. Assamagan, K. Astbury, A. Astvatsatourov, A. Atoian, G. Auerbach, B. Augsten, K. Aurousseau, M. Austin, N. Avolio, G. Avramidou, R. Axen, D. Ay, C. Azuelos, G. Azuma, Y. Baak, M.A. Bach, A.M. Bachacou, H. Bachas, K. Backes, M. Badescu, E. Bagnaia, P. Bai, Y. Bain, T. Baines, J.T. Baker, O.K. Baker, M.D. Baker, S. Dos Santos Pedrosa, F.B. Banas, E. Banerjee, P. Banerjee, S. Banfi, D. Bangert, A. Bansal, V. Baranov, S.P. Baranov, S. Barashkou, A. Barber, T. Barberio, E.L. Barberis, D. Barbero, M. Bardin, D.Y. Barillari, T. Barisonzi, M. Barklow, T. Barlow, N. Barnett, B.M. Barnett, R.M. Baroncelli, A. Barr, A.J. Barreiro, F. Barreiro Guimarães da Costa, J. Barrillon, P. Bartoldus, R. Bartsch, D. Bates, R.L. Batkova, L. Batley, J.R. Battaglia, A. Battistin, M. Bauer, F. Bawa, H.S. Bazalova, M. Beare, B. Beau, T. Beauchemin, P.H. Beccherle, R. Becerici, N. Bechtle, P. Beck, G.A. Beck, H.P. Beckingham, M. Becks, K.H. Beddall, A.J. Beddall, A. Bednyakov, V.A. Bee, C. Begel, M. Harpaz, S.B. Behera, P.K. Beimforde, M. Belanger-Champagne, C. Bell, P.J. Bell, W.H. Bella, G. Bellagamba, L. Bellina, F. Bellomo, M. Belloni, A. Belotskiy, K. Beltramello, O. Ben Ami, S. Benary, O. Benchekroun, D. Bendel, M. Benedict, B.H. Benekos, N. Benhammou, Y. Benincasa, G.P. Benjamin, D.P. Benoit, M. Bensinger, J.R. Benslama, K. Bentvelsen, S. Beretta, M. Berge, D. Bergeaas Kuutmann, E. Berger, N. Berghaus, F. Berglund, E. Beringer, J. Bernat, P. Bernhard, R. Bernius, C. Berry, T. Bertin, A. Besana, M.I. Besson, N. Bethke, S. Bianchi, R.M. Bianco, M. Biebel, O. Biesiada, J. Biglietti, M. Bilokon, H. Bindi, M. Binet, S. Bingul, A. Bini, C. Biscarat, C. Bitenc, U. Black, K.M. Blair, R.E. Blanchard, J.-B. Blanchot, G. Blocker, C. Blondel, A. Blum, W. Blumenschein, U. 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Wright, D. Wrona, B. Wu, S.L. Wu, X. Wulf, E. Wynne, B.M. Xaplanteris, L. Xella, S. Xie, S. Xu, D. Xu, N. Yamada, M. Yamamoto, A. Yamamoto, K. Yamamoto, S. Yamamura, T. Yamaoka, J. Yamazaki, T. Yamazaki, Y. Yan, Z. Yang, H. Yang, U.K. Yang, Z. Yao, W.-M. Yao, Y. Yasu, Y. Ye, J. Ye, S. Yilmaz, M. Yoosoofmiya, R. Yorita, K. Yoshida, R. Young, C. Youssef, S.P. Yu, D. Yu, J. Yuan, L. Yurkewicz, A. Zaidan, R. Zaitsev, A.M. Zajacova, Z. Zambrano, V. Zanello, L. Zaytsev, A. Zeitnitz, C. Zeller, M. Zemla, A. Zendler, C. Zenin, O. Zenis, T. Zenonos, Z. Zenz, S. Zerwas, D. della Porta, G.Z. Zhan, Z. Zhang, H. Zhang, J. Zhang, Q. Zhang, X. Zhao, L. Zhao, T. Zhao, Z. Zhemchugov, A. Zhong, J. Zhou, B. Zhou, N. Zhou, Y. Zhu, C.G. Zhu, H. Zhu, Y. Zhuang, X. Zhuravlov, V. Zimmermann, R. Zimmermann, S. Zimmermann, S. Ziolkowski, M. Živković, L. Zobernig, G. Zoccoli, A. zur Nedden, M. Zutshi, V.
Subjects: Physics::Instrumentation and Detectors, Physics::Accelerator Physics, High Energy Physics::Experiment, Nuclear Experiment
Abstract: The ATLAS detector at the Large Hadron Collider has collected several hundred million cosmic ray events during 2008 and 2009. These data were used to commission the Muon Spectrometer and to study the performance of the trigger and tracking chambers, their alignment, the detector control system, the data acquisition and the analysis programs. We present the performance in the relevant parameters that determine the quality of the muon measurement. We discuss the single element efficiency, resolution and noise rates, the calibration method of the detector response and of the alignment system, the track reconstruction efficiency and the momentum measurement. The results show that the detector is close to the design performance and that the Muon Spectrometer is ready to detect muons produced in high energy proton-proton collisions. © 2010 CERN for the benefit of the ATLAS collaboration.
Published: 2010

15. The ATLAS Simulation Infrastructure

Author: The ATLAS Collaboration Aad, G. Abbott, B. Abdallah, J. Abdelalim, A.A. Abdesselam, A. Abdinov, O. Abi, B. Abolins, M. Abramowicz, H. Abreu, H. Acharya, B.S. Adams, D.L. Addy, T.N. Adelman, J. Adorisio, C. Adragna, P. Adye, T. Aefsky, S. Aguilar-Saavedra, J.A. Aharrouche, M. Ahlen, S.P. Ahles, F. Ahmad, A. Ahmed, H. Ahsan, M. Aielli, G. Akdogan, T. Åkesson, T.P.A. Akimoto, G. Akimov, A.V. Aktas, A. Alam, M.S. Alam, M.A. Albrand, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexander, G. Alexandre, G. Alexopoulos, T. Alhroob, M. Aliev, M. Alimonti, G. Alison, J. Aliyev, M. Allport, P.P. Allwood-Spiers, S.E. Almond, J. Aloisio, A. Alon, R. Alonso, A. Alviggi, M.G. Amako, K. Amelung, C. Amorim, A. Amorós, G. Amram, N. Anastopoulos, C. Andeen, T. Anders, C.F. Anderson, K.J. Andreazza, A. Andrei, V. Anduaga, X.S. Angerami, A. Anghinolfi, F. Anjos, N. Annovi, A. Antonaki, A. Antonelli, M. Antonelli, S. Antos, J. Antunovic, B. Anulli, F. Aoun, S. Arabidze, G. Aracena, I. Arai, Y. Arce, A.T.H. Archambault, J.P. Arfaoui, S. Arguin, J.-F. Argyropoulos, T. Arik, M. Armbruster, A.J. Arnaez, O. Arnault, C. Artamonov, A. Arutinov, D. Asai, M. Asai, S. Asfandiyarov, R. Ask, S. Åsman, B. Asner, D. Asquith, L. Assamagan, K. Astbury, A. Astvatsatourov, A. Atoian, G. Auerbach, B. Augsten, K. Aurousseau, M. Austin, N. Avolio, G. Avramidou, R. Axen, D. Ay, C. Azuelos, G. Azuma, Y. Baak, M.A. Bach, A.M. Bachacou, H. Bachas, K. Backes, M. Badescu, E. Bagnaia, P. Bai, Y. Bain, T. Baines, J.T. Baker, O.K. Baker, M.D. Baker, S. Dos Santos Pedrosa, F.B. Banas, E. Banerjee, P. Banerjee, S. Banfi, D. Bangert, A. Bansal, V. Baranov, S.P. Baranov, S. Barashkou, A. Barber, T. Barberio, E.L. Barberis, D. Barbero, M. Bardin, D.Y. Barillari, T. Barisonzi, M. Barklow, T. Barlow, N. Barnett, B.M. Barnett, R.M. Baroncelli, A. Barr, A.J. Barreiro, F. Guimarães da Costa, J.B. Barrillon, P. Bartoldus, R. Bartsch, D. Bates, R.L. Batkova, L. Batley, J.R. Battaglia, A. Battistin, M. Bauer, F. Bawa, H.S. Bazalova, M. Beare, B. Beau, T. Beauchemin, P.H. Beccherle, R. Becerici, N. Bechtle, P. Beck, G.A. Beck, H.P. Beckingham, M. Becks, K.H. Beddall, A.J. Beddall, A. Bednyakov, V.A. Bee, C. Begel, M. Behar Harpaz, S. Behera, P.K. Beimforde, M. Belanger-Champagne, C. Bell, P.J. Bell, W.H. Bella, G. Bellagamba, L. Bellina, F. Bellomo, M. Belloni, A. Belotskiy, K. Beltramello, O. Ben Ami, S. Benary, O. Benchekroun, D. Bendel, M. Benedict, B.H. Benekos, N. Benhammou, Y. Benincasa, G.P. Benjamin, D.P. Benoit, M. Bensinger, J.R. Benslama, K. Bentvelsen, S. Beretta, M. Berge, D. Kuutmann, E.B. Berger, N. Berghaus, F. Berglund, E. Beringer, J. Bernat, P. Bernhard, R. Bernius, C. Berry, T. Bertin, A. Besana, M.I. Besson, N. Bethke, S. Bianchi, R.M. Bianco, M. Biebel, O. Biesiada, J. Biglietti, M. Bilokon, H. Bindi, M. Binet, S. Bingul, A. Bini, C. Biscarat, C. Bitenc, U. Black, K.M. Blair, R.E. Blanchard, J.-B. Blanchot, G. Blocker, C. Blondel, A. Blum, W. Blumenschein, U. Bobbink, G.J. Bocci, A. Boehler, M. Boek, J. Boelaert, N. Böser, S. Bogaerts, J.A. Bogouch, A. Bohm, C. Bohm, J. Boisvert, V. Bold, T. Boldea, V. Bondarenko, V.G. Bondioli, M. Boonekamp, M. Bordoni, S. Borer, C. Borisov, A. Borissov, G. Borjanovic, I. Borroni, S. Bos, K. Boscherini, D. Bosman, M. Boterenbrood, H. Bouchami, J. Boudreau, J. Bouhova-Thacker, E.V. Boulahouache, C. Bourdarios, C. Boveia, A. Boyd, J. Boyko, I.R. Bozovic-Jelisavcic, I. Bracinik, J. Braem, A. Branchini, P. Brandenburg, G.W. Brandt, A. Brandt, G. Brandt, O. Bratzler, U. Brau, B. Brau, J.E. Braun, H.M. Brelier, B. Bremer, J. Brenner, R. Bressler, S. Britton, D. Brochu, F.M. Brock, I. Brock, R. Brodet, E. Bromberg, C. Brooijmans, G. Brooks, W.K. Brown, G. Bruckman de Renstrom, P.A. Bruncko, D. Bruneliere, R. Brunet, S. Bruni, A. Bruni, G. Bruschi, M. Bucci, F. Buchanan, J. Buchholz, P. Buckley, A.G. Budagov, I.A. Budick, B. Büscher, V. Bugge, L. Bulekov, O. Bunse, M. Buran, T. Burckhart, H. Burdin, S. 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Subjects: Physics::Instrumentation and Detectors, High Energy Physics::Experiment
Abstract: The simulation software for the ATLAS Experiment at the Large Hadron Collider is being used for large-scale production of events on the LHC Computing Grid. This simulation requires many components, from the generators that simulate particle collisions, through packages simulating the response of the various detectors and triggers. All of these components come together under the ATLAS simulation infrastructure. In this paper, that infrastructure is discussed, including that supporting the detector description, interfacing the event generation, and combining the GEANT4 simulation of the response of the individual detectors. Also described are the tools allowing the software validation, performance testing, and the validation of the simulated output against known physics processes. © 2010 CERN for the benefit of the ATLAS collaboration.
Published: 2010

16. Testbeam studies of production modules of the ATLAS Tile Calorimeter

Author: Adragna, P. Alexa, C. Anderson, K. Antonaki, A. Arabidze, A. Batkova, L. Batusov, V. Beck, H.P. Bednar, P. Bergeaas Kuutmann, E. Biscarat, C. Blanchot, G. Bogush, A. Bohm, C. Boldea, V. Bosman, M. Bromberg, C. Budagov, J. Burckhart-Chromek, D. Caprini, M. Caloba, L. Calvet, D. Carli, T. Carvalho, J. Cascella, M. Castelo, J. Castillo, M.V. Cavalli-Sforza, M. Cavasinni, V. Cerqueira, A.S. Clement, C. Cobal, M. Cogswell, F. Constantinescu, S. Costanzo, D. Corso-Radu, A. Cuenca, C. Damazio, D.O. David, M. Davidek, T. De, K. Del Prete, T. Di Girolamo, B. Dita, S. Djobava, T. Dobson, M. Dolejsi, J. Dolezal, Z. Dotti, A. Downing, R. Efthymiopoulos, I. Eriksson, D. Errede, D. Errede, S. Farbin, A. Fassouliotis, D. Febbraro, R. Fedorko, I. Fenyuk, A. Ferdi, C. Ferrer, A. Flaminio, V. Francis, D. Fullana, E. Gadomski, S. Gameiro, S. Garde, V. Gellerstedt, K. Giakoumopoulou, V. Gildemeister, O. Gilewsky, V. Giokaris, N. Gollub, N. Gomes, A. Gonzalez, V. Gorini, B. Grenier, P. Gris, P. Gruwe, M. Guarino, V. Guicheney, C. Gupta, A. Haeberli, C. Hakobyan, H. Haney, M. Hellman, S. Henriques, A. Higon, E. Holmgren, S. Hurwitz, M. Huston, J. Iglesias, C. Isaev, A. Jen-La Plante, I. Jon-And, K. Joos, M. Junk, T. Karyukhin, A. Kazarov, A. Khandanyan, H. Khramov, J. Khubua, J. Kolos, S. Korolkov, I. Krivkova, P. Kulchitsky, Y. Kurochkin, Yu. Kuzhir, P. Le Compte, T. Lefevre, R. Lehmann, G. Leitner, R. Lembesi, M. Lesser, J. Li, J. Liablin, M. Lokajicek, M. Lomakin, Y. Lupi, A. Maidanchik, C. Maio, A. Makouski, M. Maliukov, S. Manousakis, A. Mapelli, L. Marques, C. Marroquim, F. Martin, F. Mazzoni, E. Merritt, F. Miagkov, A. Miller, R. Minashvili, I. Miralles, L. Montarou, G. Mosidze, M. Myagkov, A. Nemecek, S. Nessi, M. Nodulman, L. Nordkvist, B. Norniella, O. Onofre, A. Oreglia, M. Pallin, D. Pantea, D. Petersen, J. Pilcher, J. Pina, J. Pinhão, J. Podlyski, F. Portell, X. Poveda, J. Pribyl, L. Price, L.E. Proudfoot, J. Ramstedt, M. Richards, R. Roda, C. Romanov, V. Rosnet, P. Roy, P. Ruiz, A. Rumiantsev, V. Russakovich, N. Saltó, O. Salvachua, B. Sanchis, E. Sanders, H. Santoni, C. Santos, J. Saraiva, J.G. Sarri, F. Satsunkevitch, I. Says, L.-P. Schlager, G. Schlereth, J. Seixas, J.M. Selldèn, B. Shalanda, N. Shevtsov, P. Shochet, M. Silva, J. Da Silva, P. Simaitis, V. Simonyan, M. Sissakian, A. Sjölin, J. Solans, C. Solodkov, A. Soloviev, I. Solovyanov, O. Sosebee, M. Spanò, F. Stanek, R. Starchenko, E. Starovoitov, P. Stavina, P. Suk, M. Sykora, I. Tang, F. Tas, P. Teuscher, R. Tokar, S. Topilin, N. Torres, J. Tremblet, L. Tsiareshka, P. Tylmad, M. Underwood, D. Unel, G. Usai, G. Valero, A. Valkar, S. Valls, J.A. Vartapetian, A. Vazeille, F. Vichou, I. Vinogradov, V. Vivarelli, I. Volpi, M. White, A. Zaitsev, A. Zenine, A. Zenis, T.
Subjects: Physics::Instrumentation and Detectors, High Energy Physics::Experiment
Abstract: We report test beam studies of 11% of the production ATLAS Tile Calorimeter modules. The modules were equipped with production front-end electronics and all the calibration systems planned for the final detector. The studies used muon, electron and hadron beams ranging in energy from 3 to 350 GeV. Two independent studies showed that the light yield of the calorimeter was ∼ 70 pe / GeV, exceeding the design goal by 40%. Electron beams provided a calibration of the modules at the electromagnetic energy scale. Over 200 calorimeter cells the variation of the response was 2.4%. The linearity with energy was also measured. Muon beams provided an intercalibration of the response of all calorimeter cells. The response to muons entering in the ATLAS projective geometry showed an RMS variation of 2.5% for 91 measurements over a range of rapidities and modules. The mean response to hadrons of fixed energy had an RMS variation of 1.4% for the modules and projective angles studied. The response to hadrons normalized to incident beam energy showed an 8% increase between 10 and 350 GeV, fully consistent with expectations for a noncompensating calorimeter. The measured energy resolution for hadrons of σ / E = 52.9 % / sqrt(E) ⊕ 5.7 % was also consistent with expectations. Other auxiliary studies were made of saturation recovery of the readout system, the time resolution of the calorimeter and the performance of the trigger signals from the calorimeter. © 2009 Elsevier B.V. All rights reserved.
Published: 2009

17. The ATLAS Collaboration

Author: Aad, G. Abbott, B. Abdallah, J. Abdelalim, A.A. Abdesselam, A. Abdinov, O. Abi, B. Abolins, M. Abramowicz, H. Acerbi, E. Acharya, B.S. Adams, D.L. Addy, T.N. Adelman, J. Adorisio, C. Adragna, P. Adye, T. Aefsky, S. Aguilar-Saavedra, J.A. Aharrouche, M. Ahlen, S.P. Ahles, F. Ahmad, A. Ahmed, H. Ahsan, M. Aielli, G. Akdogan, T. Åkesson, T.P.A. Akimoto, G. Akimov, A.V. Alam, M.S. Alam, M.A. Albert, J. Albrand, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexander, G. Alexandre, G. Alexopoulos, T. Alhroob, M. Aliev, M. Alimonti, G. Alison, J. Aliyev, M. Allport, P.P. Allwood-Spiers, S.E. Aloisio, A. Alon, R. Alonso, A. Alviggi, M.G. Amako, K. Amelung, C. Ammosov, V.V. Amorim, A. Amorós, G. Amram, N. Anastopoulos, C. Anders, C.F. Anderson, K.J. Andreazza, A. Andrei, V. Anduaga, X.S. Angerami, A. Anghinolfi, F. Anjos, N. Antonaki, A. Antonelli, M. Antonelli, S. Antunovic, B. Anulli, F. Arabidze, G. Aracena, I. Arai, Y. Arce, A.T.H. Archambault, J.P. Arfaoui, S. Arguin, J.-F. Argyropoulos, T. Arik, M. Armbruster, A.J. Arnaez, O. Arnault, C. Artamonov, A. Arutinov, D. Asai, M. Asai, S. Asfandiyarov, R. Ask, S. Åsman, B. Asner, D. Asquith, L. Assamagan, K. Astbury, A. Astvatsatourov, A. Atoian, G. Auerbach, B. Auge, E. Augsten, K. Aurousseau, M. Austin, N. Avolio, G. Avramidou, R. Axen, D. Ay, C. Azuelos, G. Azuma, Y. Baak, M.A. Bacci, C. Bach, A. Bachacou, H. Bachas, K. Backes, M. Badescu, E. Bagnaia, P. Bai, Y. Bailey, D.C. Bain, T. Baines, J.T. Baker, O.K. Baker, M.D. Baltasar Dos Santos Pedrosa, F. Banas, E. Banerjee, P. Banerjee, S. Banfi, D. Bangert, A. Bansal, V. Baranov, S.P. Baranov, S. Barashkou, A. Barber, T. Barberio, E.L. Barberis, D. Barbero, M. Bardin, D.Y. Barillari, T. Barisonzi, M. Barklow, T. Barlow, N. Barnett, B.M. Barnett, R.M. Baroncelli, A. Barr, A.J. Barreiro, F. Barreiro Guimarães da Costa, J. Barrillon, P. Barros, N. Bartoldus, R. Bartsch, D. Bastos, J. Bates, R.L. Bathe, S. Batley, J.R. Battaglia, A. Battistin, M. Bauer, F. Bazalova, M. Beare, B. Beauchemin, P.H. Beccherle, R. Becerici, N. Bechtle, P. Beck, G.A. Beck, H.P. Beckingham, M. Becks, K.H. Beddall, A.J. Beddall, A. Bednyakov, V.A. Bee, C. Begel, M. Behar Harpaz, S. Behera, P.K. Beimforde, M. Belanger-Champagne, C. Bell, P.J. Bell, W.H. Bella, G. Bellagamba, L. Bellina, F. Bellomo, M. Belloni, A. Belotskiy, K. Beltramello, O. Ben Ami, S. Benary, O. Benchekroun, D. Bendel, M. Benedict, B.H. Benekos, N. Benhammou, Y. Benincasa, G.P. Benjamin, D.P. Benoit, M. Bensinger, J.R. Benslama, K. Bentvelsen, S. Beretta, M. Berge, D. Bergeaas Kuutmann, E. Berger, N. Berghaus, F. Berglund, E. Beringer, J. Bernardet, K. Bernat, P. Bernhard, R. Bernius, C. Berry, T. Bertin, A. Besson, N. Bethke, S. Bianchi, R.M. Bianco, M. Biebel, O. Biesiada, J. Biglietti, M. Bilokon, H. Binet, S. Bingul, A. Bini, C. Biscarat, C. Bitenc, U. Black, K.M. Blair, R.E. Blanchot, G. Blocker, C. Blondel, A. Blum, W. Blumenschein, U. Bobbink, G.J. Bocci, A. Boek, J. Boelaert, N. Böser, S. Bogaerts, J.A. Bogouch, A. Bohm, C. Bohm, J. Boisvert, V. Bold, T. Boldea, V. Boldyrev, A. Bondarenko, V.G. Bondioli, M. Boonekamp, M. Borisov, A. Borissov, G. Borjanovic, I. Borroni, S. Bos, K. Boscherini, D. Bosman, M. Boterenbrood, H. Bouchami, J. Boudreau, J. Bouhova-Thacker, E.V. Boulahouache, C. Bourdarios, C. Boyd, J. Boyko, I.R. Bozovic-Jelisavcic, I. Bracinik, J. Braem, A. Branchini, P. Brandenburg, G.W. Brandt, A. Brandt, G. Brandt, O. Bratzler, U. Brau, J.E. Braun, H.M. Brelier, B. Bremer, J. Brenner, R. Bressler, S. Breton, D. Britton, D. Brochu, F.M. Brock, I. Brock, R. Brodet, E. Bromberg, C. Brooijmans, G. Brooks, W.K. Brubaker, E. Bruckman de Renstrom, P.A. Bruncko, D. Bruneliere, R. Brunet, S. Bruni, A. Bruni, G. Bruschi, M. Bucci, F. Buchanan, J. Buchholz, P. Buckley, A.G. Budagov, I.A. Budick, B. Büscher, V. Bugge, L. Bulekov, O. Bunse, M. Buran, T. Burckhart, H. Burdin, S. Burgess, T. Burke, S. Busato, E. Bussey, P. Buszello, C.P. Butin, F. Butler, B. Butler, J.M. Buttar, C.M. Butterworth, J.M. Byatt, T. Caballero, J. Cabrera Urbán, S. Caforio, D. Cakir, O. Calafiura, P. Calderini, G. Calfayan, P. Calkins, R. Caloba, L.P. Calvet, D. Camarri, P. Cameron, D. Campana, S. Campanelli, M. Canale, V. Canelli, F. Cantero, J. Capasso, L. Caprini, I. Caprini, M. Capua, M. Caputo, R. Caracinha, D. Caramarcu, C. Cardarelli, R. Carli, T. Carlino, G. Carminati, L. Caron, B. Caron, S. Carrillo Montoya, G.D. Carron Montero, S. Carter, A.A. Carter, J.R. Carvalho, J. Casadei, D. Casado, M.P. Cascella, M. Castaneda Hernadez, A.M. Castaneda-Miranda, E. Castillo Gimenez, V. Castro, N. Cataldi, G. Catinaccio, A. Catmore, J.R. Cattai, A. Cattani, G. Caughron, S. Cauz, D. Cavalleri, P. Cavalli, D. Cavalli-Sforza, M. Cavasinni, V. Ceradini, F. Cerqueira, A.S. Cerri, A. Cerrito, L. Cerutti, F. Cetin, S.A. Cevenini, F. Chafaq, A. Chakraborty, D. Chan, K. Chapman, J.D. Chapman, J.W. Chareyre, E. Charlton, D.G. Chatterjii, S. Cheatham, S. Chekanov, S. 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Costa, M.J. Costanzo, D. Costin, T. Côté, D. Coura Torres, R. Courneyea, L. Cowan, G. Cowden, C. Cox, B.E. Cranmer, K. Cranshaw, J. Cristinziani, M. Crosetti, G. Crupi, R. Crépé-Renaudin, S. Cuenca Almenar, C. Cuhadar Donszelmann, T. Curatolo, M. Curtis, C.J. Cwetanski, P. Czyczula, Z. D'Auria, S. D'Onofrio, M. D'Orazio, A. Da Via, C. Dabrowski, W. Dai, T. Dallapiccola, C. Dallison, S.J. Dam, M. Danielsson, H.O. Dannheim, D. Dao, V. Darbo, G. Darlea, G.L. Davey, W. Davidek, T. Davidson, N. Davidson, R. Davison, A.R. Dawson, I. Daya, R.K. De, K. de Asmundis, R. De Castro, S. De Castro Faria Salgado, P.E. De Cecco, S. de Graat, J. De Groot, N. de Jong, P. De La Cruz-Burelo, E. De La Taille, C. De Mora, L. De Oliveira Branco, M. De Pedis, D. De Salvo, A. De Sanctis, U. De Santo, A. De Vivie De Regie, J.B. De Zorzi, G. Dean, S. Deberg, H. Dedovich, D.V. Defay, P.O. Degenhardt, J. Dehchar, M. Del Papa, C. Del Peso, J. Del Prete, T. Dell'Acqua, A. Dell'Asta, L. 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Ebenstein, W.L. Ebke, J. Eckert, S. Eckweiler, S. Edmonds, K. Edwards, C.A. Eerola, P. Egorov, K. Ehrenfeld, W. Ehrich, T. Eifert, T. Eigen, G. Einsweiler, K. Eisenhandler, E. Ekelof, T. El Kacimi, M. Ellert, M. Elles, S. Ellis, K. Ellis, N. Elmsheuser, J. Elsing, M. Ely, R. Emeliyanov, D. Engelmann, R. Engl, A. Epp, B. Eppig, A. Epshteyn, V.S. Ereditato, A. Eriksson, D. Ermoline, I. Ernst, J. Ernst, M. Ernwein, J. Errede, D. Errede, S. Ertel, E. Escalier, M. Escobar, C. Espinal Curull, X. Esposito, B. Etienvre, A.I. Etzion, E. Evans, H. Fabbri, L. Facius, K. Fakhrutdinov, R.M. Falciano, S. Falou, A.C. Fang, Y. Fanti, M. Farbin, A. Farilla, A. Farley, J. Farooque, T. Farrington, S.M. Farthouat, P. Fassnacht, P. Fassouliotis, D. Fatholahzadeh, B. Fayard, L. Fayette, F. Febbraro, R. Federic, P. Fedin, O.L. Fedorko, I. Feligioni, L. Felzmann, C.U. Feng, C. Feng, E.J. Fenyuk, A.B. Ferencei, J. Ferland, J. Fernando, W. Ferrag, S. Ferrando, J. Ferrari, A. Ferrari, P. Ferrari, R. Ferrer, A. Ferrer, M.L. Ferrere, D. Ferretti, C. Fiascaris, M. Fiedler, F. Filipčič, A. Filippas, A. Filthaut, F. Fincke-Keeler, M. Fiolhais, M.C.N. Fiorini, L. Firan, A. Fischer, G. Fisher, M.J. Flechl, M. Fleck, I. Fleckner, J. Fleischmann, P. Fleischmann, S. Flick, T. Flores Castillo, L.R. Flowerdew, M.J. Fonseca Martin, T. Formica, A. Forti, A. Fortin, D. Foster, J.M. Fournier, D. Fowler, A.J. Fowler, K. Fox, H. Francavilla, P. Franchino, S. Francis, D. Franklin, M. Franz, S. Fraternali, M. Fratina, S. Freestone, J. Froeschl, R. Froidevaux, D. Frost, J.A. Fukunaga, C. Fullana Torregrosa, E. Fuster, J. Gabaldon, C. Gabizon, O. Gadfort, T. Gadomski, S. Gagliardi, G. Gagnon, P. Gallas, E.J. Gallas, M.V. Gallop, B.J. Gallus, P. Galyaev, E. Gan, K.K. Gao, Y.S. Gaponenko, A. Garcia-Sciveres, M. García, C. García Navarro, J.E. Gardner, R.W. Garelli, N. Garitaonandia, H. Garonne, V. Gatti, C. Gaudio, G. Gauzzi, P. Gavrilenko, I.L. Gay, C. Gaycken, G. Gazis, E.N. Gee, C.N.P. Geich-Gimbel, Ch. Gellerstedt, K. Gemme, C. Genest, M.H. Gentile, S. Georgatos, F. George, S. Ghazlane, H. Ghodbane, N. Giacobbe, B. Giagu, S. Giakoumopoulou, V. Giangiobbe, V. Gianotti, F. Gibbard, B. Gibson, A. Gibson, S.M. Gilbert, L.M. Gilchriese, M. Gilewsky, V. Gingrich, D.M. Ginzburg, J. Giokaris, N. Giordani, M.P. Giordano, R. Giovannini, P. Giraud, P.F. Girtler, P. Giugni, D. Giusti, P. Gjelsten, B.K. Gladilin, L.K. Glasman, C. Glazov, A. Glitza, K.W. Glonti, G.L. Godfrey, J. Goebel, M. Göpfert, T. Goeringer, C. Gössling, C. Göttfert, T. Goggi, V. Goldfarb, S. Goldin, D. Golling, T. Gollub, N.P. Gomes, A. Gonçalo, R. Gong, C. González de la Hoz, S. Gonzalez Silva, M.L. Gonzalez-Sevilla, S. Goodson, J.J. Goossens, L. Gordon, H. Gorelov, I. Gorfine, G. Gorini, B. Gorini, E. Gorišek, A. Gornicki, E. Gosdzik, B. Gosselink, M. Gostkin, M.I. Gough Eschrich, I. Gouighri, M. Goujdami, D. Goulette, M. Goussiou, A.G. Goy, C. Grabowska-Bold, I. Grafström, P. Grahn, K.-J. Granado Cardoso, L. 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Sarkisyan-Grinbaum, E. Sarri, F. Sasaki, O. Sasao, N. Satsounkevitch, I. Sauvage, G. Savard, P. Savine, A.Y. Savinov, V. Sawyer, L. Saxon, D.H. Says, L.P. Sbarra, C. Sbrizzi, A. Scannicchio, D.A. Schaarschmidt, J. Schacht, P. Schäfer, U. Schaetzel, S. Schaffer, A.C. Schaile, D. Schamberger, R.D. Schamov, A.G. Schegelsky, V.A. Schernau, M. Scherzer, M.I. Schiavi, C. Schieck, J. Schioppa, M. Schlenker, S. Schmid, P. Schmitt, C. Schmitz, M. Schott, M. Schouten, D. Schovancova, J. Schram, M. Schreiner, A. Schroeder, C. Schroer, N. Schroers, M. Schultes, J. Schultz-Coulon, H.-C. Schumacher, J. Schumacher, M. Schumm, B.A. Schune, Ph. Schwanenberger, C. Schwartzman, A. Schwemling, Ph. Schwienhorst, R. Schwierz, R. Schwindling, J. Scott, W.G. Searcy, J. Sedykh, E. Segura, E. Seidel, S.C. Seiden, A. Seifert, F. Seixas, J.M. Sekhniaidze, G. Seliverstov, D.M. Sellden, B. Semprini-Cesari, N. Serfon, C. Serin, L. Seuster, R. Severini, H. Sevior, M.E. Sfyrla, A. Shan, L.Y. Shank, J.T. Shao, Q.T. Shapiro, M. Shatalov, P.B. Shaw, K. Sherman, D. Sherwood, P. Shibata, A. Shimojima, M. Shin, T. Shmeleva, A. Shochet, M.J. Shupe, M.A. Sicho, P. Sidoti, A. Siegrist, J. Sijacki, Dj. Silbert, O. Silva, J. Silverstein, D. Silverstein, S.B. Simak, V. Simic, Lj. Simion, S. Simmons, B. Simonyan, M. Sinervo, P. Sinev, N.B. Sipica, V. Siragusa, G. Sisakyan, A.N. Sivoklokov, S.Yu. Sjoelin, J. Sjursen, T.B. Skubic, P. Slater, M. Slavicek, T. Sliwa, K. Sloper, J. Sluka, T. Smakhtin, V. Smirnov, S.Yu. Smirnov, Y. Smirnova, L.N. Smirnova, O. Smith, B.C. Smith, D. Smith, K.M. Smizanska, M. Smolek, K. Snesarev, A.A. Snow, S.W. Snow, J. Snuverink, J. Snyder, S. Soares, M. Sobie, R. Sodomka, J. Soffer, A. Solans, C.A. Solar, M. Solfaroli Camillocci, E. Solodkov, A.A. Solovyanov, O.V. Soluk, R. Sondericker, J. Sopko, V. Sopko, B. Sosebee, M. Sosnovtsev, V.V. Soukharev, A. Spagnolo, S. Spanò, F. Spencer, E. Spighi, R. Spigo, G. Spila, F. Spiwoks, R. Spousta, M. Spreitzer, T. Spurlock, B. St. Denis, R.D. Stahl, T. Stamen, R. Stancu, S.N. Stanecka, E. Stanek, R.W. Stanescu, C. Stapnes, S. Starchenko, E.A. Stark, J. Staroba, P. Stastny, J. Staude, A. Stavina, P. Steinbach, P. Steinberg, P. Stekl, I. Stelzer, B. Stelzer, H.J. Stenzel, H. Stevenson, K. Stewart, G. Stockton, M.C. Stoicea, G. Stonjek, S. Strachota, P. Stradling, A. Straessner, A. Strandberg, J. Strandberg, S. Strandlie, A. Strauss, M. Strizenec, P. Ströhmer, R. Strom, D.M. Stroynowski, R. Stugu, B. Soh, D.A. Su, D. Suchkov, S.I. Sugaya, Y. Sugimoto, T. Suhr, C. Sulin, V.V. Sultansoy, S. Sun, X. Sundermann, J.E. Suruliz, K. Sushkov, S. Susinno, G. Sutton, M.R. Suzuki, T. Suzuki, Y. Sykora, I. Sykora, T. Szymocha, T. Sánchez, J. Ta, D. Taffard, A. Tafirout, R. Taga, A. Takahashi, Y. Takai, H. Takashima, R. Takeda, H. Takeshita, T. Talby, M. Talyshev, A. Tamsett, M.C. Tanaka, J. Tanaka, R. Tanaka, S. Tanaka, S. Tapprogge, S. Tardif, D. Tarem, S. Tarrade, F. Tartarelli, G.F. Tas, P. Tasevsky, M. Tassi, E. Taylor, C. Taylor, F.E. Taylor, G.N. Taylor, R.P. Taylor, W. Teixeira-Dias, P. Ten Kate, H. Teng, P.K. Terada, S. Terashi, K. Terron, J. Terwort, M. Testa, M. Teuscher, R.J. Tevlin, C.M. Thananuwong, R. Thioye, M. Thoma, S. Thomas, J.P. Thomas, T.L. Thompson, E.N. Thompson, P.D. Thompson, P.D. Thompson, R.J. Thompson, A.S. Thomson, E. Thun, R.P. Tic, T. Tikhomirov, V.O. Tikhonov, Y.A. Tipton, P. Tique Aires Viegas, F.J. Tisserant, S. Toczek, B. Todorov, T. Todorova-Nova, S. Tojo, J. Tokár, S. Tokushuku, K. Tomasek, L. Tomasek, M. Tomasz, F. Tomoto, M. Tompkins, D. Tompkins, L. Toms, K. Tonoyan, A. Topfel, C. Topilin, N.D. Torrence, E. Torró Pastor, E. Toth, J. Touchard, F. Tovey, D.R. Tovey, S.N. Trefzger, T. Tremblet, L. Tricoli, A. Trigger, I.M. Trincaz-Duvoid, S. Tripiana, M.F. Triplett, N. Trischuk, W. Trivedi, A. Trocmé, B. Troncon, C. Trzupek, A. Tsarouchas, C. Tseng, J.C.-L. Tsiakiris, M. Tsiareshka, P.V. Tsipolitis, G. Tsiskaridze, V. Tskhadadze, E.G. Tsukerman, I.I. Tsulaia, V. Tsuno, S. Turecek, D. Turk Cakir, I. Turlay, E. Tuts, P.M. Twomey, M.S. Tylmad, M. Tyndel, M. Tzanakos, G. Uchida, K. Ueda, I. Uhrmacher, M. Ukegawa, F. Unal, G. Underwood, D.G. Undrus, A. Unel, G. Unno, Y. Urbaniec, D. Urkovsky, E. Urquijo, P. Urrejola, P. Usai, G. Vacavant, L. Vacek, V. Vachon, B. Vahsen, S. Valenta, J. Valente, P. Valentinetti, S. Valkar, S. Vallecorsa, S. Valls Ferrer, J.A. van der Graaf, H. van der Kraaij, E. van der Poel, E. Van Der Ster, D. van Eldik, N. van Gemmeren, P. van Kesteren, Z. van Vulpen, I. VanBerg, R. Vandelli, W. Vaniachine, A. Vankov, P. Vannucci, F. Vari, R. Varnes, E.W. Varouchas, D. Vartapetian, A. Varvell, K.E. Vassilakopoulos, V.I. Vassilieva, L. Vazeille, F. Veillet, J.J. Vellidis, C. Veloso, F. Veneziano, S. Ventura, A. Ventura, D. Venturi, M. Venturi, N. Vercesi, V. Verducci, M. Verkerke, W. Vermeulen, J.C. Vetterli, M.C. Vichou, I. Vickey, T. Viehhauser, G.H.A. Villa, M. Villani, E.G. Villaplana Perez, M. Villate, J. Vilucchi, E. Vincter, M.G. Vinogradov, V.B. Viret, S. Virzi, J. Vitale, A. Vitells, O.V. Vivarelli, I. Vives Vaques, F. Vlachos, S. Vlasak, M. Vlasov, N. Vokac, P. Volpi, M. von der Schmitt, H. von Loeben, J. von Radziewski, H. von Toerne, E. Vorobel, V. Vorobiev, A.P. Vorwerk, V. Vos, M. Voss, R. Voss, T.T. Vossebeld, J.H. Vranjes, N. Vranjes Milosavljevic, M. Vrba, V. Vreeswijk, M. Vu Anh, T. Vudragovic, D. Vuillermet, R. Vukotic, I. Wagner, P. Wahlen, H. Walbersloh, J. Walder, J. Walker, R. Walkowiak, W. Wall, R. Wang, C. Wang, J. Wang, S.M. Ward, C.P. Warsinsky, M. Watkins, P.M. Watson, A.T. Watts, G. Watts, S. Waugh, A.T. Waugh, B.M. Webel, M. Weber, J. Weber, M.D. Weber, M. Weber, M.S. Weber, P. Weidberg, A.R. Weingarten, J. Weiser, C. Wellenstein, H. Wells, P.S. Wemans, A. Wen, M. Wenaus, T. Wendler, S. Wengler, T. Wenig, S. Wermes, N. Werner, M. Werner, P. Werthenbach, U. Wessels, M. Whalen, K. Wheeler-Ellis, S.J. White, A. White, M.J. White, S. Whiteson, D. Whittington, D. Wicek, F. Wicke, D. Wickens, F.J. Wiedenmann, W. Wielers, M. Wienemann, P. Wiglesworth, C. Wildauer, A. Wildt, M.A. Wilkens, H.G. Williams, E. Williams, H.H. Willocq, S. Wilson, J.A. Wilson, M.G. Wilson, A. Wingerter-Seez, I. Winklmeier, F. Wittgen, M. Wolter, M.W. Wolters, H. Wosiek, B.K. Wotschack, J. Woudstra, M.J. Wraight, K. Wright, C. Wright, D. Wrona, B. Wu, S.L. Wu, X. Wulf, E. Xella, S. Xie, S. Xu, N. Yamada, M. Yamamoto, A. Yamamoto, S. Yamamura, T. Yamanaka, K. Yamaoka, J. Yamazaki, T. Yamazaki, Y. Yan, Z. Yang, H. Yang, U.K. Yang, Z. Yao, W.-M. Yao, Y. Yasu, Y. Ye, J. Ye, S. Yilmaz, M. Yoosoofmiya, R. Yorita, K. Yoshida, R. Young, C. Youssef, S.P. Yu, D. Yu, J. Yuan, J. Yuan, L. Yurkewicz, A. Zaidan, R. Zaitsev, A.M. Zajacova, Z. Zambrano, V. Zanello, L. Zarzhitsky, P. Zaytsev, A. Zeitnitz, C. Zeller, M. Zema, P.F. Zemla, A. Zendler, C. Zenis, T. Zenonos, Z. Zenz, S. Zerwas, D. Zevi della Porta, G. Zhan, Z. Zhang, H. Zhang, J. Zhang, Q. Zhang, X. Zhao, L. Zhao, T. Zhao, Z. Zhemchugov, A. Zhong, J. Zhou, B. Zhou, N. Zhou, Y. Zhu, C.G. Zhu, H. Zhu, Y. Zhuang, X. Zhuravlov, V. Zimmermann, R. Zimmermann, S. Ziolkowski, M. Zitoun, R. Živković, L. Zobernig, G. Zoccoli, A. zur Nedden, M.
Published: 2009

18. UNESCO and the study of race relations in Brazil: regional or national issue?

Author: M C, Maio
Subjects: Social Identification, Sociology, United Nations, Research, Civil Rights, Race Relations, History, 20th Century, Social Change, Social Behavior, Brazil, Prejudice, Social Welfare
Published: 2007

19. [Brazil within the concert of nations: the struggle against racism in the early days of Unesco]

Author: M C, Maio
Subjects: Internationality, United Nations, Political Systems, Social Conditions, Politics, Race Relations, History, 20th Century, Brazil
Abstract: This article has the objective of approaching the political and scientific context that led Brazil to the position of Unesco paradigm for racial matters. I set out from the hypothesis that soon after the Holocaust, the positive image of race relations in Brazil was in greater evidence, becoming sort of anti-Nazi Germany. At this time, a number of unforeseen efforts took place in the sense of striving for an association between the search for understanding the German totalitarian phenomenon, the radical critique of the scientific standing of the concept of race, the evidencing of socio-economic demands of underdeveloped countries, and the choice of Brazil as a socio-anthropological laboratory. This combination of aims only became viable from the onset of a transnational political-academic alliance universalistic in nature.
Published: 2006

20. Sodium-Bearing Waste Treatment, Applied Technology Plan

Author: Lance Lauerhass, Keith J. Perry, Vince C. Maio, Arlin L. Olson, and S. Kenneth Merrill
Subjects: Data flow diagram, Nuclear technology, Engineering, Waste treatment, Conceptual design, business.industry, Process (engineering), Settlement (finance), Key (cryptography), Plan (drawing), business, Civil engineering, Construction engineering
Abstract: Settlement Agreement between the Department of Energy and the State of Idaho mandates treatment of sodium-bearing waste at the Idaho Nuclear Technology and Engineering Center within the Idaho National Engineering and Environmental Laboratory. One of the requirements of the Settlement Agreement is to complete treatment of sodium-bearing waste by December 31, 2012. Applied technology activities are required to provide the data necessary to complete conceptual design of four identified alternative processes and to select the preferred alternative. To provide a technically defensible path forward for the selection of a treatment process and for the collection of needed data, an applied technology plan is required. This document presents that plan, identifying key elements of the decision process and the steps necessary to obtain the required data in support of both the decision and the conceptual design. The Sodium-Bearing Waste Treatment Applied Technology Plan has been prepared to provide a description/roadmap of the treatment alternative selection process. The plan details the results of risk analyzes and the resulting prioritized uncertainties. It presents a high-level flow diagram governing the technology decision process, as well as detailed roadmaps for each technology. The roadmaps describe the technical steps necessary in obtaining data to quantify andmore » reduce the technical uncertainties associated with each alternative treatment process. This plan also describes the final products that will be delivered to the Department of Energy Idaho Operations Office in support of the office's selection of the final treatment technology.« less
Published: 2003
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21. [The Rio de Janeiro Medical and Surgical Society: the genesis of an alternative institutional network]

Author: L O, Ferreira, M C, Maio, and N, Azevedo
Subjects: Complementary Therapies, General Surgery, History, 19th Century, Professional Autonomy, Societies, Brazil
Abstract: Creation of the Rio de Janeiro Medical and Surgical Society serves as the basis for this study of late-19th-century medicine in Brazil. The hypothesis is that beginning in the 1880s changes to institutions and the diversification of medical community inaugurateed the structuring of a field of social relations specific to medical practitioners. With official medical institutions undergoing crises, alternative groups that emerged outside the government framework worked together toward common ends, particularly the construction of a kind of Brazilian medical knowledge that could play a role on the international scientific scenario.
Published: 2001

22. 1 Overview of Mixed Waste Solidification and Stabilization Methods

Author: Vincent C. Maio
Subjects: Stabilization methods, Waste management, Environmental science, Mixed waste
Published: 2001
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23. [Use of Valtrac in digestive surgery. Initial clinical experience]

Author: A, Monaco, G, Moncelli, L, Gastaldi, C, Verna, M, Scifo, R, Nizia, C, Maio, L, Governato, A, Deirino, F, Mangione, and P, Volterrani
Subjects: Adult, Aged, 80 and over, Male, Colon, Digestive System Diseases, Anastomosis, Surgical, Stomach, Rectum, Middle Aged, Jejunum, Surgical Staplers, Ileum, Humans, Female, Digestive System Surgical Procedures, Aged
Abstract: Stapling instruments are being currently used for digestive or colorectal anastomoses with definite advantages. The authors report their initial clinical experience about BAR utilization to restore intestinal continuity after upper digestive and colorectal resections. The authors have been carried out 20 anastomoses on 18 patients: 11 males and 7 females. Eleven (61.1%) of them were affected with malignant neoplasms and in 9 cases were performed an urgency procedure. The colorectal and jejunal-jejunal anastomoses were performed, respectively, in 8 cases; gastric-jejunal and ileo-colic anastomoses, respectively, in 2. The satisfactory results obtained seem to demonstrate that the biofragmentable anastomotic ring constitutes a "safe" method of bowel junction of the whole digestive apparatus.
Published: 1997

24. Paradental cyst of the first molar: Report of a rare case with bilateral presentation and review of the literature

Author: A E Borgonovo, P Reo, G B Grossi, and C Maiorana
Subjects: Bilateral cyst, mandibular disease, oral surgery, paradental cyst, Dentistry, RK1-715
Abstract: The paradental cyst is a lesion classified and recognized by World Health Organization quite recently, which is related to an inflammatory process, especially pericoronitis, involving a tooth in eruption. The aim of this article is to report a rare bilateral case of paradental cyst. An 8-year-old boy presented to the Oral Surgery Department, Dental Clinic, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Fondazione Ospedale Maggiore Policlinico, University of Milan, with the complaint of swelling over the buccal gingiva of his unerupted lower left first molar. Radiographs revealed a radiolucency involving the bifurcation and root area of teeth 36 and 46. The cysts were enucleated, maintaining the affected teeth in site; microscopic evaluation revealed a chronically inflamed cyst lined by a non-keratinized stratified squamous epithelium; the histopathology associated with macroscopic and radiographic examinations permitted the definitive diagnosis of a paradental cyst on the mandibular left and right first molars. The most recent literature shows the rarity of the paradental cyst occurring with bilateral localization. Because the paradental cyst can present variable clinical and radiographic signs, it is mandatory to correlate all clinical, radiographic, and histological data to obtain a definitive diagnosis.
Published: 2012
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25. [Not Available]

Author: M C, Maio and D, Batista
Subjects: Health Benefit Plans, Employee, Occupational Health Services, Industry, History, 20th Century, Railroads, Brazil, Social Security
Published: 1989

26. [Not Available]

Author: G, Hochman, M C, Maio, and N, Trindade Lima
Subjects: Insurance, Health, History, 20th Century, Brazil, Social Security
Published: 1989

27. [A case of shock due to hypersensitivity to dextran]

Author: G V, D'Arcangelo, S, Arca, and C, Maio
Subjects: Drug Hypersensitivity, Humans, Dextrans, Shock, Middle Aged
Abstract: An examination is made of the relevant literature in the light of a case of shock due to serious hypersensitivity to high molecular weight (70,000) dextran. It is shown that similar cases occur with a certain frequency when dextran is used in situations other than surgery and frank shock. The reaction explodes in response to the first drops of the first administration. The ready availability of resuscitation equipment is a fundamental requisite for the satisfactory outcome of treatment.
Published: 1980

28. An overview of burning mouth syndrome

Author: Enrica Gentile, C Maio, Mariasofia Tammaro, Agostino Guida, Dorina Lauritano, Alberta Lucchese, Carmen Salerno, Dario Di Stasio, Rosario Serpico, Massimo Petruzzi, Salerno, C, Di Stasio, D, Petruzzi, M, Lauritano, D, Gentile, E, Guida, A, Maio, C, Tammaro, M, Serpico, R, Lucchese, A, Salerno, Carmen, Di Stasio, Dario, Petruzzi, Massimo, Lauritano, Dorina, Gentile, Enrica, Guida, Agostino, Maio, Claudio, Tammaro, Mariasofia, Serpico, Rosario, and Lucchese, Alberta
Subjects: Burning mouth syndrome, oral diseases, oral medicine, oral biology, dentistry, 0301 basic medicine, Benzylamines, medicine.medical_specialty, Oral health, Lidocaine, education, 030106 microbiology, oral medicine, Chronic pain, Oral pain, Review, Clonazepam, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Pharmacotherapy, oral biology, Prevalence, Humans, Medicine, oral diseases, LS7_2, Oral mucosa, Burning Sensation, MED/26 - NEUROLOGIA, dentistry, General Immunology and Microbiology, business.industry, digestive, oral, and skin physiology, Ambientale, MED/28 - MALATTIE ODONTOSTOMATOLOGICHE, Burning mouth syndrome, 030206 dentistry, medicine.disease, Dermatology, Dysgeusia, stomatognathic diseases, medicine.anatomical_structure, Capsaicin, medicine.symptom, business, medicine.drug
Abstract: Burning mouth syndrome (BMS) is characterised by the presence of a burning sensation in the oral mucosa in the absence of any clinically apparent mucosal sign. It occurs more commonly in older women and often affects the tongue tip and lateral borders, lips, and hard and soft palates. Besides the burning sensation, patients with BMS may complain of unremitting oral mucosal pain, dysgeusia, and xerostomia. The exact pathophysiology of primary BMS remains unknown. A major challenge for the clinician is the treatment of BMS: identifying possible causative factors is the first step, but BMS is often idiopathic. Drug therapy, in addition to behavioural therapy and psychotherapy, may help to eliminate the symptoms. Considering the growing incidence of BMS in older people, further research is required to determine the true efficacy of current management strategies for patients with this disorder.

29. A medicina de Nina Rodrigues: análise de uma trajetória científica

Author: Marcos C. Maio
Subjects: História da Medicina, História da Antropologia, História da Ciência, Medicina Legal, Medicine, Public aspects of medicine, RA1-1270
Abstract: Uma das maneiras mais profícuas de se pesquisar a história da medicina brasileira na passagem do século XIX para o XX é a investigação da trajetória profissional de determinados médicos que tiveram posições de relevo no processo de mudanças que atingiu o campo médico à época. Neste sentido, este artigo tem por objetivo analisar a carreira acadêmico-profissional de Raimundo Nina Rodrigues, a partir da noção de campo científico de Pierre Bourdieu. Partindo do princípio de que o campo médico é um espaço de confrontos estruturalmente determinado pelos embates passados, onde os médicos buscam monopolizar a autoridade/competência científica, considero que o perfil médico de Nina Rodrigues é um indicador preciso do processo de especialização e concorrência que se desenvolveu naquele momento.

30. Metric analysis of the patella for sex estimation in a Portuguese sample.

Author: Maio C, Cunha E, and Navega D
Abstract: The biological profile estimation is the first step toward positive identification. However, it is not always possible to access a complete and well-preserved skeleton due to postmortem damage and taphonomic changes. As such, there is a need to develop new alternatives to analyze different bones of the human skeleton. The present study aims to analyze the patellar osteometry, with attention to its degree of sexual dimorphism, to establish a simple method for estimating sex in Portuguese adults. Six measurements were taken from 222 patella pairs, including 117 females and 105 males from the XXI Century Identified Skeleton Collection of the University of Coimbra. Subsequently, this method was validated in a different sample of 50 individuals equally representing both sexes. Maximum height stands out with a 77.0% of correct sex estimation, reaching 98.0% when applied to the new sample. The linear discriminant function analysis containing all the six variables showed the best results, with 80.2% of correct classification after cross-validation and 96.0% when applied to the independent sample., (© The Author(s) 2024. Published by OUP on behalf of the Academy of Forensic Science.)
Published: 2024
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31. When Alice Took Sertraline: A Case of Sertraline-Induced Alice in Wonderland Syndrome.

Author: Vilela M, Fernandes D, Salazar T Sr, Maio C, and Duarte A
Abstract: Alice in Wonderland syndrome (AIWS) is a rare disorder that refers to episodic body image distortions, sometimes associated with altered perception of external space and time. AIWS is mainly associated with viral disease in children as well as migraines and epileptic seizures in adults. Its pathogenesis is still very much unknown and there are not many reported drug-associated cases in medical literature. We describe a case of a 67-year-old woman, with a relevant history of depressive disorder, nontoxic goiter, and dyslipidemia that presented short episodes of altered body perception associated with altered external space perception for a period of one week. Her physical examination was unremarkable and her cerebral computerized axial tomography (cerebral CAT) and blood tests showed no alterations. She had been medicated with sertraline till the previous year and had restarted it in the previous month. She reported similar episodes of body image distortions in the first weeks of initiating sertraline for the first time. The current episode lasted for two weeks and in one year follow-up she reported no recurrence. The patient was diagnosed with AIWS probably induced by sertraline, being the first reported case of the kind., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2020, Vilela et al.)
Published: 2020
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32. Psychiatric disorders in oral lichen planus: a preliminary case control study.

Author: Di Stasio D, Lauritano D, Gritti P, Migliozzi R, Maio C, Minervini G, Petruzzi M, Serpico R, Candotto V, and Lucchese A
Subjects: Aged, Case-Control Studies, Humans, Anxiety complications, Depression complications, Lichen Planus, Oral complications, Lichen Planus, Oral psychology
Abstract: The aim of this study was to evaluate the prevalence of psychiatric symptoms in patients with oral lichen planus (OLP) compared to a control group. Eleven patients (mean age 65.2 years-old), with diagnosis of OLP and 13 controls (mean age 64.8 years-old) underwent a psychiatric evaluation with five psychometric scales: Visual Analogue Scale (VAS), Hamilton Rating Scale for Depression (HAM-D), State-Trait Anxiety Inventory (STAI 1-2), Distress Thermometer (DT) and Brief Fatigue Inventory (BFI). Seventy-three % of OLP group presented a VAS score of mild type; 9% had depressive symptoms; 100% of the sample had a score above the cut-off for state and trait anxiety; 45% presented Distress (36% moderate type). However, no statistical difference was found in comparison with the control group. In this study, there was no difference in these parameters between the OLP group and the control group. Perhaps, a larger cohort of patients could give different results.
Published: 2018

33. Depression and distress in burning mouth syndrome: A case control study.

Author: Di Stasio D, Candotto V, Serpico R, Migliozzi R, Petruzzi M, Tammaro M, Maio C, Gritti P, Lauritano D, and Lucchese A
Subjects: Anxiety complications, Case-Control Studies, Fatigue complications, Humans, Quality of Life, Burning Mouth Syndrome complications, Burning Mouth Syndrome psychology, Depression complications
Abstract: To compare the results of psychometric tests in patients with BMS and controls, participants were tested for depression, anxiety, fatigue and distress. Patients with BMS had noticeably higher scores for depression, fatigue and distress, compared to controls. Depression and distress were significantly correlated with the burning symptom. Moreover, distress and burning symptoms proved to be interdependent. Depression seems to play a specific role in BMS. Burning symptoms affect quality of life of patients and they could be a predictor of distress.
Published: 2018

34. Telescopic overdenture on natural teeth: prosthetic rehabilitation on (OFD) syndromic patient and a review on available literature.

Author: Minervini G, Romano A, Petruzzi M, Maio C, Serpico R, Lucchese A, Candotto V, and Di Stasio D
Subjects: Anodontia, Dental Caries, Humans, Denture, Overlay, Orofaciodigital Syndromes rehabilitation
Abstract: Orofaciodigital syndromes (OFD) are rare genetical disorders characterized by malformations of the mouth (oris), face (facies), hands and feet (digitus = finger, toe). It is still impossible to fully understand the whole spectrum of all dysfunctions due to OFD, since the expressions of the syndrome vary in each patient. There are various alterations, thoroughly described in literature that can affect the oral cavity such as dental caries, abnormal teeth, enamel hypoplasia, supernumerary teeth and dental agenesis. A syndromic patient with a complex picture showing conditions such as palatine fissures and a severe hypodontia has to be treated using a multidisciplinary approach, and in particular, needs a prosthetic rehabilitation for the restoration of missing dental elements in the arch.
Published: 2018

35. Systemic and topical photodynamic therapy (PDT) on oral mucosa lesions: an overview.

Author: Di Stasio D, Romano A, Gentile C, Maio C, Lucchese A, Serpico R, Paparella R, Minervini G, Candotto V, and Laino L
Subjects: Humans, Photosensitizing Agents administration & dosage, Photosensitizing Agents pharmacology, Photosensitizing Agents therapeutic use, Mouth Diseases drug therapy, Mouth Diseases pathology, Mouth Mucosa drug effects, Mouth Mucosa pathology, Photochemotherapy
Abstract: Photodynamic Therapy (PDT) is a minimally invasive treatment that has shown promising results in treating preneoplasticlesions. PDT reckons on the administration of a drug (photosensitizer), which can be used in a topical or systemic form. Photodynamic therapy has been successfully used in the management of a variety of pathologies from different anatomical sites, including the head, neck, brain and lungs, hepatobiliary tree and other gastrointestinal and urological pathologies, skin, gynaecological conditions and in vascular anomalies. Starting from these same considerations, PDT has also been adopted for oral malignant and premalignant lesions treatment, and should be kept under investigation as a promising therapeutic management of leukoplakia and preneoplastic lesions of the oral cavity.
Published: 2018

36. Oral-facial-digital syndrome (OFD): 31-year follow-up management and monitoring.

Author: Minervini G, Romano A, Petruzzi M, Maio C, Serpico R, Di Stasio D, and Lucchese A
Subjects: Dental Caries, Dental Enamel Hypoplasia, Follow-Up Studies, Humans, Tooth, Supernumerary, Orofaciodigital Syndromes diagnosis, Orofaciodigital Syndromes therapy
Abstract: Orofaciodigital syndrome (OFD) is a group of hereditary disorders identified by malformations of the mouth (oris), face (facies), hands and feet (digitus=finger and toe). Although there are several different types reported in the literature, there is a great overlap in their clinical presentation. The full spectrum of all disorders due to OFD is not yet fully understood, since each patient shows variations in the expression of the syndrome. In the oral cavity, teeth are often affected by various alterations, such as dental caries, abnormal teeth, enamel hypoplasia, supernumerary teeth and dental agenesis. Treatment of a syndromic patient with a complex picture showing conditions such as palatine fissures and a severe hypodontia involves a multidisciplinary approach and a careful periodical follow-up.
Published: 2018

37. The potential role of in vivo optical coherence tomography for evaluating oral soft tissue: A systematic review.

Author: Gentile E, Maio C, Romano A, Laino L, and Lucchese A
Subjects: Humans, Mouth diagnostic imaging, Mouth Diseases diagnostic imaging, Tomography, Optical Coherence
Abstract: Background: The introduction of optical coherence tomography (OCT) in dentistry enabled the integration of already existing clinical and laboratory investigations in the study of the oral cavity. This systematic review presents an overview of the literature, to evaluate the usefulness of in vivo OCT for diagnosing oral soft tissues lesions, to compare the OCT results with traditional histology, and to identify limitations in prior studies so as to improve OCT applications., Methods: We performed a review of the literature using different search engines (PubMed, ISI Web of Science, and the Cochrane Library) employing MeSH terms such as "optical coherence tomography" and "OCT" in conjunction with other terms. We utilized the Population, Intervention, Comparison, Outcomes, and Study design (PICOS) method to define our study eligibility criteria., Results: Initial results were 3155. In conclusion, there were only 27 studies which met our selection criteria. We decided to allocate the 27 selected items into three groups: healthy mucosa; benign, premalignant, and malignant lesions; and oral manifestations of systemic therapies or pathological conditions., Conclusions: Although the OCT is an easy-to-perform test and it offers an attractive diagnostic and monitoring prospect for soft tissues of the oral cavity, further studies are needed to complete the current knowledge of this imaging technique., (© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Published: 2017
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38. The potential role of in vivo reflectance confocal microscopy for evaluating oral cavity lesions: a systematic review.

Author: Lucchese A, Gentile E, Romano A, Maio C, Laino L, and Serpico R
Subjects: Autoimmune Diseases diagnosis, Autoimmune Diseases pathology, Humans, Microscopy, Confocal instrumentation, Mouth Diseases diagnosis, Mouth Mucosa diagnostic imaging, Mouth Mucosa pathology, Mouth Neoplasms diagnostic imaging, Mouth Neoplasms pathology, Precancerous Conditions diagnosis, Precancerous Conditions pathology, Microscopy, Confocal methods, Mouth Diseases diagnostic imaging, Mouth Diseases pathology
Abstract: Background: Since the early 2000s, several studies have examined the application of reflectance confocal microscopy (RCM) to the oral cavity. This review gives an overview of the literature on reflectance confocal microscopy analysis of the oral cavity in vivo and identifies flaws in the studies, providing guidance to improve reflectance confocal microscopy applications and inform the design of future studies., Methods: The PubMed, ISI, Scopus, and Cochrane Library databases were searched for publications on RCM using the terms 'reflectance confocal microscopy' in combination with 'mouth' and other terms related to the topic of interest., Results: The search gave 617 results. Seventeen studies were included in our final analysis. We decided to organize the selected articles according to four topics: healthy mucosa, autoimmune diseases, cancer and precancerous lesions, and hard dental tissues., Conclusion: Although reflectance confocal microscopy is promising for diagnosing and monitoring oral pathology, it has shortcomings and there are still too few publications on this topic. Further studies are needed to increase the quantity and quality of the results, to translate research into clinical practice., (© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Published: 2016
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39. An overview of burning mouth syndrome.

Author: Salerno C, Di Stasio D, Petruzzi M, Lauritano D, Gentile E, Guida A, Maio C, Tammaro M, Serpico R, and Lucchese A
Subjects: Benzylamines administration & dosage, Burning Mouth Syndrome diagnosis, Burning Mouth Syndrome epidemiology, Burning Mouth Syndrome physiopathology, Capsaicin administration & dosage, Capsaicin therapeutic use, Clonazepam administration & dosage, Humans, Lidocaine administration & dosage, Prevalence, Burning Mouth Syndrome therapy
Abstract: Burning mouth syndrome (BMS) is characterised by the presence of a burning sensation in the oral mucosa in the absence of any clinically apparent mucosal sign. It occurs more commonly in older women and often affects the tongue tip and lateral borders, lips, and hard and soft palates. Besides the burning sensation, patients with BMS may complain of unremitting oral mucosal pain, dysgeusia, and xerostomia. The exact pathophysiology of primary BMS remains unknown. A major challenge for the clinician is the treatment of BMS: identifying possible causative factors is the first step, but BMS is often idiopathic. Drug therapy, in addition to behavioural therapy and psychotherapy, may help to eliminate the symptoms. Considering the growing incidence of BMS in older people, further research is required to determine the true efficacy of current management strategies for patients with this disorder.
Published: 2016
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40. Career patterns of physician assistants: a retrospective longitudinal study.

Author: Warner ML, Maio C, and Hudmon KS
Subjects: Adult, Aged, Attitude of Health Personnel, Female, Humans, Longitudinal Studies, Male, Middle Aged, Retrospective Studies, Career Mobility, Physician Assistants, Specialization statistics & numerical data
Abstract: Objectives: A distinguishing characteristic of the physician assistant (PA) profession is career flexibility to move between specialties without further training or certification. The objectives of this study were to characterize the number and type of practice specialties and to explore attitudes towards career flexibility., Methods: Practice patterns were examined using a survey of AAPA member and non-member graduates from the classes of 1978, 1988, and 1998., Results: Overall, respondents (n = 1,703; 31%) reported practicing in an average of 1.95 specialty practices per decade over the course of their career (range, 1-18; SD, 1.40). Adjusted for the number of decades elapsed postgraduation, the 1978, 1988, and 1998 cohorts practiced in an average of 1.08 (SD, 0.71), 1.51 (SD, 1.02), and 2.41 (SD, 1.49) specialties per decade, respectively (P < 0.0001; all pair-wise comparisons significant, P < 0.001)., Conclusions: Most PAs change specialties during their career, and this trait of the profession is highly valued.
Published: 2013
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41. [Use of Valtrac in digestive surgery. Initial clinical experience].

Author: Monaco A, Moncelli G, Gastaldi L, Verna C, Scifo M, Nizia R, Maio C, Governato L, Deirino A, Mangione F, and Volterrani P
Subjects: Adult, Aged, Aged, 80 and over, Colon surgery, Digestive System Diseases surgery, Female, Humans, Ileum surgery, Jejunum surgery, Male, Middle Aged, Rectum surgery, Stomach surgery, Anastomosis, Surgical instrumentation, Digestive System Surgical Procedures, Surgical Staplers
Abstract: Stapling instruments are being currently used for digestive or colorectal anastomoses with definite advantages. The authors report their initial clinical experience about BAR utilization to restore intestinal continuity after upper digestive and colorectal resections. The authors have been carried out 20 anastomoses on 18 patients: 11 males and 7 females. Eleven (61.1%) of them were affected with malignant neoplasms and in 9 cases were performed an urgency procedure. The colorectal and jejunal-jejunal anastomoses were performed, respectively, in 8 cases; gastric-jejunal and ileo-colic anastomoses, respectively, in 2. The satisfactory results obtained seem to demonstrate that the biofragmentable anastomotic ring constitutes a "safe" method of bowel junction of the whole digestive apparatus.
Published: 1997

42. Different behavioral effects of haloperidol, clozapine and thioridazine in a concurrent lever pressing and feeding procedure.

Author: Salamone JD, Cousins MS, Maio C, Champion M, Turski T, and Kovach J
Subjects: Animals, Male, Rats, Rats, Sprague-Dawley, Time Factors, Antipsychotic Agents pharmacology, Clozapine pharmacology, Conditioning, Operant drug effects, Feeding Behavior drug effects, Haloperidol pharmacology, Thioridazine pharmacology
Abstract: Rats were tested using a lever pressing/feeding procedure in which a preferred food (Bioserve pellets) was available by pressing a lever on a fixed ratio 5 schedule, but a less preferred food (lab chow) was also available concurrently in the operant chamber. The effects of repeated (14 day) injections of haloperidol, clozapine and thioridazine were compared. Haloperidol (0.05-0.15 mg/kg) significantly reduced lever pressing and increased chow intake throughout the drug treatment period. Injections of clozapine (2.0-6.0 mg/kg) suppressed lever pressing but failed to produce substantial increases in chow intake. In the haloperidol experiment there was a significant inverse correlation between lever pressing and chow intake, but in the clozapine experiment there was not. Regression analysis indicated that rats treated with the high dose of clozapine showed some tolerance to the suppression of lever pressing. Tests of sedation also were conducted before and after the instrumental behavior sessions. Haloperidol produced little or no sedative effect in the dose range tested. Clozapine produced substantial sedation during the first 10 days of administration, but this effect, like the suppression of lever pressing, showed signs of tolerance. Thioridazine (3.0-9.0 mg/kg) produced some effects that resembled haloperidol, and other effects, including sedation, that resembled clozapine. These studies indicate that haloperidol suppresses lever pressing for food at low doses that do not produce severe motivational or sedative effects that disrupt food intake. In contrast, it appears as though the suppression of lever pressing produced by clozapine stems from a sedative effect that also serves to set limits on chow intake. These results indicate that haloperidol and clozapine suppress lever pressing through different mechanisms.
Published: 1996
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43. Symplastic leiomyoma of the scrotum. A case report.

Author: De Rosa G, Boscaino A, Giordano G, Donofrio V, Staibano S, Maio C, and Iandolo M
Subjects: Humans, Male, Middle Aged, Leiomyoma pathology, Muscle Neoplasms pathology, Muscle, Smooth pathology, Scrotum
Abstract: Mesenchimal tumors of the scrotum are rare lesions. Here, we describe a case of symplastic leiomyoma of the scrotum, in a 49-year old man. This is the third case reported in the world literature. Grossly, the lesion is a white-gray nodule, with fasciculated pattern, on sectioning. Histologically, the neoplasm is formed by whorling bundles of fusiform cells, which have atypical nuclei, with occasional cytoplasmatic inclusions. Mitoses are absent. The muscolar nature of the lesion is demonstrated by positivity for Masson-trichrome stain and for actin and desmine antigens.
Published: 1996

44. [A case of shock due to hypersensitivity to dextran].

Author: D'Arcangelo GV, Arca S, and Maio C
Subjects: Humans, Middle Aged, Dextrans adverse effects, Drug Hypersensitivity complications, Shock chemically induced
Abstract: An examination is made of the relevant literature in the light of a case of shock due to serious hypersensitivity to high molecular weight (70,000) dextran. It is shown that similar cases occur with a certain frequency when dextran is used in situations other than surgery and frank shock. The reaction explodes in response to the first drops of the first administration. The ready availability of resuscitation equipment is a fundamental requisite for the satisfactory outcome of treatment.
Published: 1980

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