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Danışman: DR. ÖĞR. ÜYESİ ÇİĞDEM ÖNER Yer Bilgisi: İstanbul Gelişim Üniversitesi / Lisansüstü Eğitim Enstitüsü / Antrenörlük Eğitimi Ana Bilim Dalı / Spor Yönetimi Bilim Dalı Konu: Spor = Sports Dizin: Grup iletişimi = Group communication ; Spor kulüpleri = Sports clubs ; Sporcular = Sportsmen ; Takım ruhu = Team spirit ; Takım uyumu = Team cohesion ; Voleybol = Volleyball ; Voleybolcular = Volleyball players ; Yaratıcı drama = Creative drama ; Öz güven = Self confidence ; İletişim = Communication, Bu araştırmada, yaratıcı drama programının elit kadın voleybolcuların uyum, iletişim ve güven düzeylerine etkisinin belirlenmesi amacıyla öntest-sontest kontrol gruplu deneysel araştırma modeli uygulanmıştır. Araştırmada 3 farklı ölçek kullanılmıştır. Bunlar ; İletişim Yeterlilik Ölçeği (Wiemann, 1977; Koca ve Erigüç 2017), Sporda Kendine Güven Kaynakları Ölçeği (Walley vd., 1988; Miçoğulları ve Kirazcı, 2010), Takım Birlikteliği Envanteri (Carron vd., 1985 ; Unutmaz , Kiremitçi ve Gencer, 2011) . Sporda Kendine Güven Kaynakları ölçeğininin Cronbach Alfa güvenirlik katsayısı, birinci takımda hesaplanan Cronbach Alfa katsayısı değeri 0,864, ikinci takımda hesaplanan Cronbach Alfa katsayısı değeri 0,955, üçüncü takımda hesaplanan Cronbach Alfa katsayısı değeri 0,939'dur. Takım bireyleri kaynaklarına ilişkin ölçeğin Cronbach Alfa katsayısı değeri, ölçme aracının homojenliğinin bir göstergesi olup, birinci takımda hesaplanan Cronbach Alfa katsayısı değeri 0,713, ikinci takımda hesaplanan Cronbach Alfa katsayısı değeri 0,616, üçüncü takımda hesaplanan Cronbach Alfa katsayısı değeri 0,731'dir. İletişim düzeyi kaynaklarına ilişkin ölçeğin Cronbach Alfa katsayısı değeri, birinci takımda hesaplanan Cronbach Alfa katsayısı değeri 0,793, ikinci takımda hesaplanan Cronbach Alfa katsayısı değeri 0,858, üçüncü takımda hesaplanan Cronbach Alfa katsayısı değeri 0,685'dur. Verilerin analizi SPSS 26,0 isimli paket programda gerçekleştirilmiştir. Verilerin analizinde, grup içi ve gruplar arası tanımlayıcı istatistik yapılmıştır. Bu bulgulara bakıldığında grupların parametrik olarak dağıldığı gözlemlenmiştir. Kulanmış olduğumuz ölçekler ile deney ön test & son test ile kontrol grubu ön & son test arasında karşılaştırmalı analiz yapılmıştır, bu analizde ANOVA' dan faydalanılmıştır. Bu analiz sonucunda aralarında anlamlı sonuç çıkması halinde Post Hoc Tukey testinden yararlanılmıştır. Araştırmada fonksiyonel ilişki düzeyini görebilmek için çoklu Regresyon analizinden faydalanılmıştır. Bu değişkenler arasında doğrusal ilişkiler tespit edilmiştir. Her bir değişken arasında ilişki katsayısını görebilmek için Pearson Corelation testinden yararlanılmıştır. Bu araştırma 2020-2021 Türkiye voleybol profesyonel 2.ligi, Küçükçekmece voleybol kulübünden, 30 elit kadın voleybolcuyla yapılmıştır. Deney grubunun tamamı ortaöğretim mezunudur. Kontrol grubunun, %13,3'ü ise lisans mezunudur. 30 kişilik sporcu grubunda ortalama yaşlar 15 olup, deney grubu en az 13 , en fazla 17, kontrol grubu en az 13 en çok 26 yaşındadır. Gruplarda sporculuk deneyimi ortalaması deney grubunda 4 yıl, kontrol grubunda 7 yıl, yarışma deneyimleri ortalaması ise deney grubu 4 yıl kontrol grubu da 5 yıldır. Bulgulara göre, 8 oturumluk yaratıcı drama programının sporcularda uyum, kendine güven ve iletişim düzeyine etkisi, yaratıcı drama eğitimi alan voleybolcular (deney grubu) ile yaratıcı drama eğitimi almayan voleybolcular (kontrol grubu) arasında istatiksel olarak anlamlı bir farklılık olduğunu göstermiştir. Araştırmanın amacı doğrultusunda yapılan alan yazın incelemesinde, sporcularda yaratıcı drama programının iletişim, kendine güven ve takım birlikteliği üzerinde ki etkisinin ölçümlendiği bir çalışmaya rastlanmamış olması bu çalışmanın özgünlüğünü ortaya koymaktadır. Bilimsel bilginin kademe kademe yükselebileceği gereğinden hareketle tasarlanan bu çalışmanın bilim insanlarına, psikolojik performans danışmanlarına, sporun yöneticilerine, antrenörlere, sporculara ve yeni araştırmacılara ışık tutacağı ve alan yazında önemli bir boşluğu doldurarak literatüre katkı sağlayacağı düşünülmektedir., In this study, an experimental research model with pretest-posttest control group was applied in order to determine the effect of the creative drama program on the conformity, communication and confidence levels of elite female volleyball players. Three different scales were used in the study. These ; Communication Competence Scale (Wiemann, 1977; Koca and Erigüç 2017), Sources of Self-Confidence in Sports (Walley et al., 1988; Miçoğulları and Kirazcı, 2010), Team Collaboration Inventory (Carron et al., 1985; Forgetz , Kiremitçi and Gencer, 2011) ) . Cronbach's alpha reliability coefficient Confidence in Sports Resources of the scale, the first team calculated Cronbach's alpha coefficient is 0.864, both calculated on the team, nc Cronbach Alpha coefficient value is 0.955, Cronbach Alpha coefficient value calculated in the third team is 0.939. The Cronbach Alpha coefficient value of the scale regarding the resources of the team members is an indicator of the homogeneity of the measurement tool, the Cronbach Alpha coefficient calculated in the first team is 0.713, the Cronbach Alpha coefficient calculated in the second team is 0.616, and the Cronbach Alpha coefficient calculated in the third team is 0.731. Scale level, of communication resource Cronbach 's alpha coefficient value is first set in the calculation of Cronbach's alpha coefficient is 0.793, as calculated in the second team Cronbach's alpha coefficient is 0.858, as calculated in the third set Cronbach The alpha coefficient value is 0.685. The analysis of the data was carried out in a package program named SPSS 26 .0 . In the analysis of the data , descriptive statistics were made within and between groups. Considering these findings, it was observed that the groups were distributed parametrically . Kula been experimenting with scales and preliminary tests we & test control group was made a comparative analysis between the pre & post-test, ANOVA, this analysis' is used. Post Hoc Tukey test was used if there were significant results between them as a result of this analysis . Multiple Regression analysis was used in the research to see the level of functional relationship. Linear relationships were found between these variables. Pearson Corelation test was used to see the correlation coefficient between each variable . This research was conducted with 30 elite female volleyball players from the Küçükçekmece volleyball club, in the 2020-2021 Turkish professional volleyball league. All of the experimental group are secondary school graduates. The control group , a graduate degree is 13.3% . The average age in the 30-person athlete group is 15 , the experimental group is at least 13, at most 17, and the control group is at least 13 and at most 26 years old. According to the findings, the effect of the 8-session creative drama program on the level of harmony, self-confidence and communication in the athletes showed that there was a statistically significant difference between the volleyball players who received creative drama training (experimental group) and volleyball players who did not receive creative drama training (control group). In the literature review conducted in line with the purpose of the research, the fact that no study was found in which the effect of creative drama program on communication, self-confidence and team cohesion was measured in athletes reveals the originality of this study. It is thought that this study, which was designed based on the requirement that scientific knowledge can rise gradually , will shed light on scientists, psychological performance counselors, sports managers, coaches , athletes and new researchers and will contribute to the literature by filling an important gap in the literature.

WOS: 000332000400025 PubMed: 24381109 In this study we have retrospectively analysed the mutation spectrum of the 351 Familial Mediterranean fever patients referred to KA +/- rA +/- kkale University Faculty of Medicine, Department of Medical Genetics Laboratory over a period of 5 years and compared them with Turkey's mean. We have found 11 different mutations, including rare mutations such as F479L, K695R, M680I(G/A) and 45 different genotypes showing the heterogeneity of MEFV mutations in Central Anatolia. The most three prevalent mutations were M694V (14.8 %), E148Q (7.1 %) and M680I(G/C) (4.1 %) in accordance with the literature. We have also investigated R202Q in our routine molecular diagnosis. Mutation causing R202Q (c.605G > A) change was described as a frequent polymorphism and G allele was found in linkage disequilibrium (LD) with M694V. There are limited number of studies investigating R202Q, some of them implicate that its homozygote state is disease causing. We showed the high frequency of R202Q (23.7 %) with and without M694V in all the groups analysed and its high LD rate with M694V in the diagnosed group. Our study is reflecting the mutational heterogeneity of MEFV and summarize mutational spectrum of Turkey's geographical regions and overall Turkey.

Familial Mediterranean Fever (FMF) is an autosomal recessive genetic disorder characterised by recurrent and self-limited abdominal pain, synovitis and pleuritis. MEFV gene mutations are responsible from the disease and its protein product, pyrin or marenostrin, plays an essential role in the regulation of the inflammatory reactions. MEFV gene contains 10 exons and most of the mutations have been found on the last exon. Up to date, 152 mutations and polymorpisms have been reported inwhere V726A, M694V, M694I, M680I and E148Q are the most common mutations. In this study, MEFV allele frequencies of 136 individuals (60 from Pediatry, 76 from Internal Medicine) have been evaluated, and compared with each other. Asymptomatic individuals with FMF family history (4 from Pediatry, 6 from Internal Medicine) were excluded from the analysis. The prominent mutations indicated in the Pediatry group are V726A, M694V and M680I (G/C) and with the allele frequency of 0.06, 0.05 and 0.04 respectively while they were E148Q, M694V, M680I (G/C) in the Internal Medicine group with the allele frequency of 0.12, 0.08 and 0.04. The E148Q mutation is significantly overrepresented in the adult referrals (P = 0.02). Mutation on both alleles was observed in only 12% of cases. Overall mutation frequency was low, seen in 26.2% (66/252). However, when only diagnosed patients were analyzed it is 72.7% (16/22). It is also interesting that 63% of individuals are female that there may be sex influence on FMF phenotype.

Alstrom syndrome is a rare autosomal recessive disorder characterized by retinal degeneration, sensorineural hearing loss, obesity, type 2 diabetes mellitus and chronic nephropathy. It may be associated with acanthosis nigricans, hypergonadotropic hypogonadism, hepatic dysfunction, hepatic steatosis, hyperlipidaemia, dilated cardiomyopathy and short stature. We report a patient with Alstrom syndrome who had hypergonadotropic hypogonadism, hepatic dysfunction, hepatic steatosis and short stature with normal body weight, all of which are seen infrequently with this syndrome.

Background The aim of the present study was to assess the correlation of immunohistochemical subtyping with clinical diagnosis in order to achieve useful epidemiological data regarding amyloidosis in Turkish patients. Method We carried out immunohistochemical studies on 128 biopsies from various sites of 111 patients with biopsy-proven amyloidosis and, based on the results, classified the patients. We assessed the correlation of immunohistochemical subtype with clinical diagnosis and gathered epidemiological data. Results The sites most biopsied were kidney and rectum, followed by the testicle, liver, small intestine and bladder. Amyloid deposits showed positive staining with a single antibody in 120 biopsies. Pure amyloid A (AA) positivity was seen in 113 biopsies; six biopsies were positive for amyloid lambda (AL) and one for beta2-microglobulin (beta2MG). The clinical diagnoses of 81 patients (98 biopsies all AA positive) were suggestive of familial Mediterranean fever (FMF). Also AA positive were eight patients with tuberculosis, seven patients with rheumatoid arthritis, four patients with bronchiectasis and one patient with Crohn's disease. The biopsies from seven patients clinically suspected to have plasma cell dyscrasias were AL positive. One patient undergoing haemodialysis was beta2MG positive. Two patients without definite diagnoses showed double or triple positivity, which could not be interpreted and classified immunohistochemically. Conclusions This study demonstrates that the predominant association of AA amyloidosis is with FMF. It also suggests that the routine immunohistochemical study of patients with amyloidosis who are of certain ethnic backgrounds suffices for classifying the subtype of amyloid fibril protein and the related disease.

In order to obtain data on blood pressure (BP) distribution in Turkish children, a total of 5,599 Turkish children from birth to 18 years were studied. BP rises with age, and both systolic and diastolic BP showed a positive correlation with height and weight in both sexes. As the sampling was representative of Turkish children at different ages, the mean systolic and diastolic BP levels were compared for each age with the results reported in the study of the Second Task Force. The mean systolic and diastolic BP of Turkish children and the increase with growth and development were different from the Second Task Force study. Genetic, ethnic, and environmental factors were suggested to be responsible for this variation. In conclusion, normal BP curves should be applied with caution in childhood, and every population should use their own normal standards to define a measured BP level in children.

ensari, arzu/0000-0001-7036-4457 WOS: 000334521000017 PubMed: 23981758 AimCoexistence of familial Mediterranean fever (FMF) with various systemic vasculitides, including Henoch-Schonlein purpura (HSP) and other inflammatory disorders has been reported and the MEFV gene has been suggested to play an important role in the pathogenesis of this association. In the present study, the mutation rate of the MEFV gene in HSP and its association with the clinical course of the disease were evaluated. MethodThe study group comprised 68 children (36 boys and 32 girls) diagnosed as having HSP. The spectrum and degree of organ involvement and the levels of serum C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were documented for each patient. Allele-specific PCR using oligonucleotide probes which include 12 MEFV mutations (E148Q, P369S, F479L, M680I [G/C], M680I [G/A], I692del, M694V, M694I, K695R, V726A, A744S, R761H) were used for mutation analysis. ResultsOf the 68 patients studied, 50 (74%) showed no mutation, while 18 (26%) had MEFV mutation. Mutation analysis of the whole group revealed that 15 (22%) patients were heterozygous for one of the screened MEFV mutations, while three (4.5%) patients were compound heterozygous for two of the studied mutations, and one (1.5%) patient was homozygous for E148Q/E148Q mutations. Gastrointestinal and joint involvement, and edema were more frequently observed in patients with MEFV mutations, while ESR and CRP levels were significantly higher (P

Objective: A cross-sectional study was performed to evaluate the prevalence of enuresis nocturna (EN) among 6-10 year-old primary school children in Kırıkkale. Material and Method: Children (n:1500) aged between 6-10 years were included in the study. Questionnaires were answered by the parents to evaluate the demographic and voiding characteristics, time of toilet training, dysfunctional voiding (DV) symptoms, prevalence of EN, methods and results of EN treatment. DV score (DVS) validated for Turkish children were surveyed and scores greater than 8.5 were considered significant. Results: Children (n:1372) who completed the questionnaire were included in the study. The mean age of students was 8.27 years (M: F: 707:659). EN was noted in 11.4 % (n:157, group 1) of children. EN history was noted in 37.5 % (n:515, group 2) of children, and 51.1 % (n:700, group 3) of them had never EN. Toilet training was completed after 5 years of age in 5.2 % of the students with EN and 1.3 % of the children without EN (p

Gallstone spillage during laparoscopic cholecystectomy is a relatively common occurrence. These intraperitoneal gallstones are considered to be harmless. Rarely, they may give rise to complications. Surgeons should retrieve spilled stones whenever possible.We report the case of a 75-year-old man with retroperitoneal abscess that developed 6 years following laparoscopic cholecystectomy as a late complication. The cavity, though it drained purulent material, was sterile in culture. Gallstones were found in the drain effluent. To our knowledge this is the first case report in English of such a delayed complication caused by spilled gallstones.Every effort should be made to avoid perforation of the gall bladder during its dissection. Whether the procedure should be converted to open surgery to retrieve all the stones is subject to debate.

Background: Although early treatment is valuable in the prognosis of crush syndrome, the diagnosis and treatment of many victims are inevitably delayed in major disasters. Patients and Methods: Among the 38 victims of the Marmara earthquake with crush injury, 27 were diagnosed as crush syndrome on the basis of findings of acute renal failure. Intensive intravenous fluid treatment was started in all patients on admission. Of these 27 patients, 10 required dialysis treatment while 17 did not. The laboratory data on admission were evaluated and compared between the two groups. Results: The mean admission time of 27 patients was 46.5 ± (SE) 3.08 h. There was no significant difference between the dialysis and the nondialysis groups with regard to patient’s age, trapped time or admission time. A significantly higher number of patients had crush injury in more than one extremity in the dialysis group. The dialysis group had significantly lower systolic blood pressure, central venous pressure but a higher heart rate together with higher levels of serum urea nitrogen, creatinine, creatinine kinase, C-reactive protein, fibrinogen on admission compared to the nondialysis group. Conclusion: Our results suggest that even delayed application of aggressive specific fluid treatment under close monitoring may prevent the development of established acute renal failure.

Background: Various immunological abnormalities leading to impaired immune status have been described in uraemic adults; however, few data are available for uraemic children. Methods: In this study, peripheral blood total lymphocyte count and lymphocyte subsets (CD3+, CD4+, CD8+, CD16+, CD20+) were evaluated, skin tests with PPD and Candida antigens were performed, and serum immunoglobulin (IgG, IgA, IgM) and complement (C3, C4) levels were measured in 30 children with end-stage renal failure (10 before dialysis, 10 on continuous ambulatory peritoneal dialysis, and 10 on haemodialysis) and the results compared with those of 15 healthy controls. Results: The data showed significant lymphopenia in predialysis and haemodialysis groups. No significant change was observed in the CD4+/CD8+ ratio or in the percentages of lymphocyte subsets in either group studied, while the absolute values of some lymphocyte subsets were significantly lower in all groups as compared with controls. In skin test evaluation, only the patients in the predialysis group showed a significantly decreased response to Candida antigen. The serum immunoglobulin levels were significantly decreased in the continuous ambulatory peritoneal dialysis group as compared with the control group. Conclusion: Our results, together with those of other paediatric studies, reported in the literature, suggest that uraemic children are not immunocompromised, though the effects of uraemia may cause some variation in their immune status.

PubMed: 18187500 Background. Haemodialysis treatment can be very tiring and unpleasant, particularly for paediatric patients, families and also for the treatment team. In this study, the basic needs of children on haemodialysis were determined in order to improve the conditions of their therapy environment. Methods. The requirements of 20 children and 40 adults, who were on haemodialysis therapy for a minimum of five sessions, were recorded by means of a questionnaire. Results. The majority of children and adults preferred to be treated in separate units. All children and adults stated that they needed a constant transportation facility to be provided by the dialysis unit. All children wanted their parents/relatives to be with them during the dialysis sessions while only a minority of adults required an accompanying relative. The majority of both paediatric and adult patients preferred daytime sessions. The majority of children preferred to have the same nurse to needle their fistula and supervise their therapy session. Conclusions. The health authority should recognize the role of the therapy team, including a paediatric nephrologist, in providing the basic needs and fulfilling the expectations of paediatric haemodialysis patients in order to increase the efficiency of the treatment. © The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

A 22-month-old girl with nephrotic syndrome and microcephaly is described. She had dysmorphic facies and psychomotor retardation. Her parents were first-degree relatives and one of her siblings had died with nephrotic syndrome and renal failure in infancy. An autosomal recessive inheritance is suggested. The diagnosis of this rare combination is discussed and the relevant literature is reviewed.