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Canine parvovirus 2 (CPV-2) is an important causative agent of segmental enteritis in young dogs and has globally distributed variants and subtypes. Viral mutations can alter the pathogenesis and clinical signs, making identifying the samples circulating in a given region relevant. This study described the epidemiological and clinical findings and the molecular characterization of CPV-2 samples circulating in the canine population of Uruguaiana, Rio Grande do Sul (RS), Brazil. We analyzed 27 cases with a complete clinical history and at least one confirmatory etiologic diagnosis. In addition to clinical and epidemiological data, whole blood samples or tissues were tested by PCR for viral DNA detection. Amplified products were sequenced and analyzed, and phylogeny was generated with reference sequences. The disease was diagnosed especially in the summer months, and the most common clinical findings were diarrhea, anorexia, listlessness, and vomiting. Infection was predominant in young (< 6 months) unvaccinated or partially immunized dogs, with mortality exceeding 93%. It was possible to identify 15 CPV-2 samples, four of which were CPV-2a and 11 were new CPV-2a. It can be concluded that canine parvovirus is a disease with high mortality rates, with young unvaccinated dogs being more susceptible, with a predominance of the new CPV-2a variant in the western region of Rio Grande do Sul. [ABSTRACT FROM AUTHOR]

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

It aimed to compare the trans anesthetic clinical and perioperative analgesic effects by prolonged continuous infusion of fentanyl (GF, bolus of 5 µg/kg and continuous infusion (CI) of 15 µg/kg/h) or remifentanil (GR, CI of 18 µg/kg/h) in dogs undergoing to elective ovariohysterectomy. Twenty female healthy dogs were premedicated with acepromazine, inducted to unconsciousness with propofol and kept under anesthesia with isoflurane. The M0 (baseline) was recorded and animals were randomly allocated in GF (n = 10) or GR (n = 10), recording clinical and blood gas parameters every 15 minutes (M15...M120) for two hours and, after, during surgery, adjusting the opioid rate according to surgical requirement. The isoflurane vaporization reduced by up to 47% and 42% in GF and GR, respectively, when compared to M0. During the first two hours of CI, six animals of each group required atropine intervention and three animals of GF required ephedrine. The number of rate adjustments during intraoperative was significant higher in GR when compared to GF (P = 0.0248). By the Log-rank test, there was a higher possibility of not receiving analgesic rescue in the first 30 minutes of postoperative in GF when compared to GR (P < 0.0001) and all animals required analgesic rescue during the firsts 3 and 6 hours in GR and GF, respectively. It is concluded that, when the proposal continuous infusions were compared, fentanyl required fewer analgesic rescues during perioperative, nonetheless, it is recommended rate adjustment during intraoperative and additional analgesia for postoperative for both treatments. [ABSTRACT FROM AUTHOR]

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[Introduction] Compressed air energy storage (CAES) is a technology for storing electrical energy on a large scale, only second to pumped storage in terms of scale. The gas storage device is an important component of CAES. The gas storage facilities of compressed air energy storage power plants that have been put into commercial operation domestically and abroad are mostly natural geological structures such as salt caverns and abandoned mines. Large-scale, long-term compressed air energy storage requires more economical and widely applicable gas storage facilities. [Method] Artificial underground cavern gas storage facilities largely freed compressed air energy storage power plants from the reliance on specific geological conditions, becoming a strong support for the large-scale construction of long-term compressed air energy storage power plants. However, there were few research achievements in this field domestically and internationally. Understanding the research status at home and abroad, summarizing advanced experiences from other industries, and clarifying the challenges that need to be addressed urgently in this field had significant implications for the large-scale construction of compressed air energy storage power plants. [Result] There are significant differences in the operating characteristics between artificial underground caverns in compressed air energy storage power plants and conventional artificial caverns such as natural gas storage facilities and hydroelectric water conveyance tunnels, and there is a lack of mature design methods and regulations for this field, with many technological challenges still awaiting resolution. This paper reviews the characteristics and key research contents of underground artificial caverns in compressed air energy storage power plants. [Conclusion] Prioritizing safety, considering cost-effectiveness and fostering innovation provide a guarantee for the independent development of the underground hard rock gas storage facilities for compressed air energy storage power plants. This technology holds practical significance in enriching China's energy storage and power generation experiences, and improving new power systems. If this technology matures, it can provide strong support for the construction of a new power system in China.

Extrachromosomal circular DNA (eccDNA) has recently gained increasing attention due to its significant role in cancer and other pathophysiologic states. The majority of circular DNAs detected by Circle-seq are small-size eccDNAs with enigmatic functions. One major technical hurdle is to synthesize eccDNA for functional identification. Here, we describe CAES (Circle-seq based Artificial EccDNA Synthesis), a promising and reliable method for artificial eccDNA synthesis. Eight eccDNAs carrying different microRNA genes (eccMIR) found in gastric cancer tissues, ranging from 329 bp to 2189 bp in size, were created utilizing the CAES method. Exonuclease V and single restriction-endonuclease digestion identified the circular structure of synthetic eccDNAs. The DNA circularization efficiency afforded by CAES ranged from 15.6% to 31.1%, which was negatively correlated with the eccDNA length. In addition, we demonstrated that CAES-synthesized eccMIRs can express both miRNA-3p and − 5p molecules efficiently independent of a canonical promoter in human cell lines. Further assays proved that these eccMIRs were functional as they were able to repress the luciferase gene containing a miRNA-target sequence in the 3′UTR as well as the endogenous mRNA targets. Finally, kinetics study revealed that eccDNA exhibited a decay rate similar to the standard plasmids and linear DNA in cultured cells. Together, this study offers a rapid and convenient method for Circle-seq users to synthesize artificial eccDNAs. It also demonstrates the promising potential of eccMIR as a bacterial DNA-free vector for safe and robust miRNA overexpression in both basic research and therapeutic applications.

Sinonasal neoplasms represent approximately 1% of all neoplasms and represent a major challenge for treatment. The treatment of nasal tumors must be local, and radiotherapy can be a good option in these cases. This study evaluated the therapeutic response of canine sinonasal neoplasms to megavoltage radiotherapy, and consequently, its influence on the survival and quality of life of these animals. We included 26 dogs with sinonasal neoplasms through histopathological and cytological examination. Dogs were treated with radiotherapy at total doses of 42–54 Gy (for carcinomas) and 45 Gy (for sarcomas) in 15–18 fractions of 2.8–3.0 Gy. Tumor staging was performed based on skull tomography. The most frequent clinical signs of sinonasal neoplasms were sneezing, nasal noise, and epistaxis. Acute side effects were mild and more frequent. Survival was evaluated based on tumor stage, obtaining a mean overall survival of 329 days (95% confidence interval, 229–428) and a median of 252.5 days. The survival time in animals in stage T3/T4 was significantly shorter than that in those in stage T1/T2 (P < 0.05). Moreover, 86.4% of the treated animals showed clinical improvement. Radiotherapy was well tolerated by dogs and effective in controlling sinonasal neoplasms. [ABSTRACT FROM AUTHOR]

Copyright of Natural Gas Industry is the property of Natural Gas Industry Journal Agency and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The potential energy of compressed air represents a multi-application source of power. Historically employed to drive certain manufacturing or transportation systems, it became a source of vehicle propulsion in the late 19th century. During the second half of the 20th century, significant efforts were directed towards harnessing pressurized air for the storage of electrical energy. Today's systems, which are based on storing the air at a high pressure, are usually recognized as compressed air energy storage (CAES) installations. This paper aims to provide an overview of different technologies that take advantage of the energy accumulated in the compressed air. Particular attention is paid to the CAES installations that are working as electrical energy storage systems (EESs). These systems, developed originally as large capacity (>100 MWe) and fuel-based installations, may soon become fully scalable, highly efficient, and fuel-free electrical energy storage systems. To present this opportunity, a thorough review encompassing previous and up-to-date advancements in their development was carried out. In particular, CAES concepts, such as diabatic (D-CAES), adiabatic (A-CAES), and isothermal (I-CAES), are described in detail. This review also provides the detailed characteristics of the crucial elements of these configurations, including compressors, expanders, air storage chambers, and thermal storage tanks. Knowledge of these components and their role allows us to understand the main challenges behind the further development of the mentioned CAES setups. Apart from the CAES systems that are designed as EES systems, this paper describes other prospective technologies that utilize the energy of pressurized air. Accordingly, compressed air cars and their key elements are explained in detail. Moreover, the technology renowned as wave-driven compressed air energy storage (W-CAES) is described as well, indicating that the utilization of pressurized air represents a viable option for converting ocean energy into electrical power. [ABSTRACT FROM AUTHOR]

Hip dysplasia (CFD) is the most common orthopedic case in small animal clinics, and, from this, other conditions can arise, such as lateral dislocation of the patella. The objective of this work is to present the preventive surgical treatment for DCF, using the technique of juvenile pubic symphysiodesis (SPJ), and also the surgical treatment to correct lateral patellar dislocation using the trochlear chondroplasty technique in a 4-month-old canine patient., who had hip instability and a history of lameness in the right pelvic limb. SPJ constitutes a prophylactic treatment for FCD that consists of the induced suspension of bone growth in the pubic symphysis region. Trochlear chondroplasty was the technique for deepening the trochlear groove which, together with intervention in the soft tissues, had the function of fixing the patella in its anatomical position. It is concluded that the use of the SPJ technique had the main function of preventing CFD in a young animal, just as trochlear chondroplasty had the reestablishment of normal function of the affected limb. [ABSTRACT FROM AUTHOR]

Despite renewable energy source integration being a well-established requirement in international policies, energy systems still face some unresolved issues, including the intermittence of production. To tackle this problem, a viable solution could comprise the off-peak storage of electricity production excess, to be consumed later during peak-load hours. The transition from the diffuse pattern of centralized generation to the distributed model, involving energy communities, suggests an additional aspect to manage: the spatial constraints of systems for domestic applications. Compressed-air energy storage represents a promising Power-to-Power technology for small-scale energy integration. This study proposes the application of a gas–liquid energy storage system (GLES) in a residential building, using renewable energy excess from a photovoltaic (PV) array. The performance of the proposed system, whose operation involves the compression of the gaseous mass through a piston operated by mineral oil, was evaluated through energy analysis performed simulating the devices and their coupling with the load profiles of the building. The thermodynamic model of storage was validated using data from an experimental campaign on a prototype. A sensitivity study, acting on the features of the system, such as the compression rate and vessel size, allowed us to compare the absorbed PV energy excess, the coverage of the building energy demand during the expansion phase, and the electrical efficiency of a daily cycle. The results obtained, together with the related economic analysis, were used to quantify the market potential of the proposed solution, to be exploited as a mechanical alternative to conventional electric batteries in dwellings. [ABSTRACT FROM AUTHOR]

The maintenance of power balance poses significant challenges in renewable combined deregulated power systems due to the unpredictable nature of renewable energy sources. This situation leads to economic instability within the system. However, an energy storage system can help maintain energy supply and control system stability for renewable incorporated thermal power plants. Unlike in regulated markets, energy prices in deregulated markets are not fixed by any government body or particular company. Instead, the Independent System Operator (ISO) serves as the main entity in the electrical market, gathering tenders from Generation Companies (GENCOs), Distribution Companies (DISCOs), and Transmission Companies (TRANSCOs). The market controller regulates energy prices using Nodal Pricing (NP), which provides economic benefits to both GENCOs and DISCOs. However, the unpredictability of renewable sources often results in a decline in system profit due to the production of an imbalance price (CostIMC) caused by a mismatch in contracted power generation from the renewable power plant. To address these issues, this study proposes a novel combined system that utilizes a suitable scheduling technique for the optimum operation of a wind farm-compressed air energy storage (CAES) system to maximize profit and revenue while maintaining grid frequency. The CAES system's energy level is divided into four different levels, and an optimal strategy has been developed to efficiently utilize the CAES system to maintain grid frequency. This work has been conducted in both regulated and deregulated environments using a modified IEEE 30-bus system. The proposed method has been compared with an existing approach and has yielded better results in all aspects. [ABSTRACT FROM AUTHOR]

In the present era, the electrical network faces difficulty owing to the restricted supply of conventional energy resources. Solar and wind power are supremely acceptable renewable energy around the globe due to their cheap availability, zero fuel costs, and environmental safety features. Maintaining power balance in a renewable combined day‐ahead power network becomes challenging owing to the uncertainty of renewable sources, resulting in economic instability. An energy‐storing device is essential for combining renewable sources with existing thermal power plants to control the energy supply and maintain system stability. Any government agency in the deregulated market does not set up energy pricing. The ISO (independent system operator) is the primary organization in the day‐ahead power network that is responsible for collecting energy bids from DISCOs (distribution companies), TRANSCOs (transmission companies), and GENCOs (generation companies). The energy pricing is set by the market regulator at a rate known as Location‐based marginal pricing (LBMP), which provides benefits to GENCOs, and DISCOs as well as the customers. In a deregulated market, the unpredictability of renewable sources affects system profit owing to the creation of instability cost (ISC), induced by mismatching the bidding power production from the renewable plant. To lessen these concerns, the presented approach has proposed an innovative model that employs ideal scheduling of the WF (wind‐farm)‐CAES (compressed‐air‐energy‐storage)‐fuel cell (FC) hybrid systems to enhance system economic profitability while keeping the grid frequency (GF) in the safe zone. The fuel cell acts as the energy‐storing device that can be utilized during high‐demand times on the grid, with the ultimate goal of maximizing profits for the overall system. The CAES system's energy level is separated into four dissimilar points, and this study presents an optimum approach for efficiently using it to maintain grid frequency. The new strategy outperformed the previous methods in all categories. The study was performed using the IEEE 30 bus test system. [ABSTRACT FROM AUTHOR]

Infectious enteritis is highly prevalent among dogs worldwide and, in some cases, it can be fatal. This study describes the clinical and laboratorial findings of single and mixed infections associated with severe enteritis in 76 dogs from Southern Brazil. Intestinal segments and/or fecal samples were subjected to histopathology and molecular detection of DNA viruses, bacteria and protozoa. Severe intestinal lesions were observed in most cases. Single infections were detected in 52.6% of cases, double (36.8%) and triple (10.5%) infections were also identified. Carnivore protoparvovirus 2 (CPV-2) was the most frequent agent in single infections (36.8%). Coinfection by CPV-2 and Giardia spp. was the most common in dual infections (19.7%), followed by CPV-2 and Cryptosporidium spp. (10.5%). The most frequent triple infection was CPV-2, Giardia sp. and Cryptosporidium spp. (6.6%). Our results shown that single and mixed infections are associated with severe enteritis in dogs in southern Brazil, mainly involving CPV-2 and Giardia sp. [ABSTRACT FROM AUTHOR]

This survey analyzed data obtained through a questionnaire on the clinical approaches used by veterinarians to treat dogs with epileptic seizures. We found that neurological examinations were performed by 12% of the respondents, blood tests by 85%, and computed tomography by 72%. In addition, serology for infectious disease detection was mentioned by 30% of the respondents, and 72% did not classify epileptic seizures. According to the answers, the treatment of choice was phenobarbital in 100% of cases which was combined with potassium bromide in 19%. Moreover, 51% of the respondents mentioned that they monitored the serum phenobarbital levels. The study results showed disagreements on the conduct and care recommended by the International Veterinary Epilepsy Task Force consensus. [ABSTRACT FROM AUTHOR]

Copyright of Acta Veterinaria Brasilica is the property of Acta Veterinaria Brasilica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Veterinaria Brasilica is the property of Acta Veterinaria Brasilica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Veterinaria Brasilica is the property of Acta Veterinaria Brasilica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Brasileira de Reprodução Animal is the property of Revista Brasileira de Reproducao Animal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Digestive endoscopy is an advanced and non-invasive technology that contributes to the diagnosis and therapeutic management of the various diseases of the gastrointestinal tract that affect canines. The advantages of the technique include diagnostic accuracy, easier handling and the possibility of collecting samples through biopsy, however, its limitations are linked to complications in the anesthetic procedure and the difficulty in evaluating some structures. Thus, gastroscopy, the focus of this study, is a widely used tool that aims to help resolve clinical conditions in patients affected by different gastropathies. Therefore, the objective of this study was to promote, based on a literature review, a general approach to this examination in dogs, highlighting the main aspects of the technique and its application. [ABSTRACT FROM AUTHOR]

Copyright of Revista Academica Ciencia Animal is the property of Revista Academica Ciencia Animal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

It is usually to conduct a full-scale three-dimensional flow analysis for a radial turbine to find a way to increase the efficiency of a Compressed Air Energy Storage (CAES) system. However, long solving time and huge consumption of computing resources become a major obstacle to the analysis. Therefore, in present study, a surrogate model with test data-based multi-layer perceptron (MLP) Neural Network is proposed to overcome the difficulty. Instead of complex flow field solving process, it provides reliable turbine aerodynamic performance and flow field distribution characteristics in a short solution time by "learning the measurement results". The validation results illustrated that the predicted maximum relative errors of isentropic efficiency, corrected mass flow rate and corrected power are only 0.03%, 0.22% and 0.26% respectively. The predicted flow distribution parameters in chamber, shroud cavity and outlet region of rotor are also basically consistent with the experimental results. In the chamber, it can be found that a pressure stagnation point is observed at circumferential angle of 270° when total pressure ratio is decreased. In the shroud cavity, obvious pressure variation is found near outlet of shroud cavity which although labyrinth seals exist. At outlet of rotor, obvious variations of velocity and pressure are found in the 0.0–0.4 and 0.6–0.8 of blade height. At the same time, obvious variations of velocity and pressure are found in the 0.0–0.4 and 0.6–0.8 of blade height and this is because the influence of upper passage vortex, lower passage vortex and end wall secondary flow. The present study can provide further reference for the dynamic performance evaluation of CAES radial inflow turbine. [ABSTRACT FROM AUTHOR]

With the widespread recognition of underground salt cavern compressed air storage at home and abroad, how to choose and evaluate salt cavern resources has become a key issue in the construction of gas storage. This paper discussed the condition of building power plants, the collection of regional data and salt plant data, and the analysis of stability and tightness. Comprehensive analysis and evaluation methods were put forward from four aspects, including ground comprehensive conditions, regional geological conditions and formation lithology, salt mine characteristics, stability, and tightness of salt caverns. The limit equilibrium theory was applied to establish the limit equilibrium failure mode of salt caverns under operating pressure, and the stability coefficient calculation method of the target salt cavern was determined by combining the mechanical characteristics. Based on the physical and mechanical properties of salt rocks, it was found that salt rocks with enough thickness around the salt cavity could be used as sealing rings to ensure the tightness of the salt cavern. Combined with the field water sealing test, the tightness of the target salt cavern is verified. This method has been applied to the salt cavern screening and evaluation of a 300 MW compressed air energy storage power plant project in Yingcheng, Hubei Province, and remarkable results have been obtained, indicating the rationality of the method. [ABSTRACT FROM AUTHOR]

The integration of an increasing share of Renewable Energy Sources (RES) requires the availability of suitable energy storage systems to improve the grid flexibility and Compressed Air Energy Storage (CAES) systems could be a promising option. In this study, a CO2-free Diabatic CAES system is proposed and analyzed. The plant configuration is derived from a down-scaled version of the McIntosh Diabatic CAES plant, where the natural gas is replaced with green hydrogen, produced on site by a Proton Exchange Membrane electrolyzer powered by a photovoltaic power plant. In this study, the components of the hydrogen production system are sized to maximize the self-consumption share of PV energy generation and the effect of the design parameters on the H2-CAES plant performance are analyzed on a yearly basis. Moreover, a comparison between the use of natural gas and hydrogen in terms of energy consumption and CO2 emissions is discussed. The results show that the proposed hydrogen fueled CAES can effectively match the generation profile and the yearly production of the natural gas fueled plant by using all the PV energy production, while producing zero CO2 emissions. [ABSTRACT FROM AUTHOR]

Introdução: A proximidade entre o ser humano e os animais de companhia tem vindo a ser cada vez mais frequente. No entanto, esta aproximação torna-se um risco para a infeção por agentes zoonóticos como parasitas intestinais dos cães e gatos. Objetivos: Neste estudo foi avaliada a contaminação de espaços públicos com formas parasitárias intestinais de cães e gatos. Foi também realizada uma entrevista com um questionário a tutores com a finalidade de avaliar a perceção destes quanto às rotinas que pudessem representar risco de infeção humana e hábitos de desparasitação dos animais. Material e Métodos: Foram analisadas 120 amostras de fezes e 55 amostras de solo provenientes de parques e jardins públicos, parques infantis, parques caninos, praias e centros escolares. Utilizou-se para a análise das amostras fecais o método de Willis e o método de sedimentação simples, e para as amostras de solo, o método de Rugai. Também foram realizadas 101 entrevistas aos tutores que passeavam os seus cães. Resultados Foi observada a prevalência de parasitismo em 17,5% de amostras fecais e 67,3% nas amostras de solo. Nas amostras fecais a prevalência foi de 14,2% Toxocara spp., 4,2% ancilostomídeos, 0,8% Dipylidium caninum e 0,8% Cystoisospora spp. Nas amostras de solo a prevalência foi de 54,5% família Taeniidae, 29,1% Toxocara spp., 23,6% ancilostomídeos, 3,6% Dipylidium caninum, 3,6% Cystoisospora spp. e 1,8% Strongyloides spp. Nas entrevistas, 88,1% dos tutores afirmou recolher as fezes dos seus cães, em 54,5% dos cães não se realizava a desparasitação interna com regularidade, 86,1% dos animais tinha acesso aos quartos, camas e sofás dos tutores, 72,3% dos tutores permitiam que os cães lambessem a sua face e 84,2% dos tutores desconhecia o significado da palavra “zoonose”. Conclusões: Foi observada uma elevada prevalência de parasitismo nas fezes e no ambiente com formas parasitárias de elevado risco zoonótico como Toxocara spp., Ancylostoma spp. Dipylidium caninum e Strongyloides spp. O contato próximo dos animais com os tutores revelou ser um risco para infeções parasitárias zoonóticas, devendo ser encorajadas campanhas de sensibilização e educação da população nas vertentes humana, animal e ambiental e adoção de uma abordagem “Uma só Saúde”.

A anestesia epidural é um tipo de técnica anestésica locorregional utilizada para auxiliar na analgesia trans e pós-operatória, bloqueando a nocicepção cirúrgica diretamente nas raízes nervosas que saem da medula espinhal utilizando os anestésicos locais. As abordagens existentes para realização desta técnica são a toracolombar, lombossacral e sacrococcígea, tendo esta última uma segurança maior devido à ausência de cone medular e saco dural, com isso, o presente relato objetivou demonstrar a técnica epidural através da abordagem sacrococcígea como uma opção mais segura para cães de pequeno porte. A paciente passou por implantação de uma prótese de tróclea em membro pélvico direito devido a osteoartrose da rima troclear e a técnica escolhida para bloqueio locorregional foi anestesia epidural sacrococcígea com utilização de lidocaína 0,25 ml/kg e morfina 0,1 mg/kg. Durante o procedimento cirúrgico não foi necessário resgate analgésico assim como não foi necessário resgate para o pós-operatório, sendo utilizado apenas dipirona 25mg/kg e meloxicam 0,1 mg/kg. O despertar foi tranquilo e sem indícios de dor, concluindo que a abordagem sacrococcígea garante efeitos tão satisfatórios quanto a abordagem lombossacral, e com menos chances de intercorrências.

A pitiose configura-se como uma infecção piogranulomatosa crônica que afeta o trato gastrointestinal de pequenos animais ou a pele, sendo provocada pelo patógeno transmitido pela água, Pythium insidiosum. Esta revisão bibliográfica explora a capacidade da avaliação ultrassonográfica abdominal, abrangendo o estômago, duodeno, jejuno e cólon, como método de auxílio no diagnóstico de pitiose gastrointestinal em cães, bem como os principais achados encontrados em pacientes acometidos pela doença.

The potential energy of compressed air represents a multi-application source of power. Historically employed to drive certain manufacturing or transportation systems, it became a source of vehicle propulsion in the late 19th century. During the second half of the 20th century, significant efforts were directed towards harnessing pressurized air for the storage of electrical energy. Today’s systems, which are based on storing the air at a high pressure, are usually recognized as compressed air energy storage (CAES) installations. This paper aims to provide an overview of different technologies that take advantage of the energy accumulated in the compressed air. Particular attention is paid to the CAES installations that are working as electrical energy storage systems (EESs). These systems, developed originally as large capacity (>100 MWe) and fuel-based installations, may soon become fully scalable, highly efficient, and fuel-free electrical energy storage systems. To present this opportunity, a thorough review encompassing previous and up-to-date advancements in their development was carried out. In particular, CAES concepts, such as diabatic (D-CAES), adiabatic (A-CAES), and isothermal (I-CAES), are described in detail. This review also provides the detailed characteristics of the crucial elements of these configurations, including compressors, expanders, air storage chambers, and thermal storage tanks. Knowledge of these components and their role allows us to understand the main challenges behind the further development of the mentioned CAES setups. Apart from the CAES systems that are designed as EES systems, this paper describes other prospective technologies that utilize the energy of pressurized air. Accordingly, compressed air cars and their key elements are explained in detail. Moreover, the technology renowned as wave-driven compressed air energy storage (W-CAES) is described as well, indicating that the utilization of pressurized air represents a viable option for converting ocean energy into electrical power.

Na cirurgia de remoção de neoplasias mamárias a obtenção de margens livres é importante para predizer a eficácia do procedimento. O objetivo deste estudo foi avaliar a relação das margens com os achados clínicos e histopatológicos de cadelas com neoplasia mamária submetidas à exérese cirúrgica. Foi realizado um estudo retrospectivo, no período de 2016 à 2020, de 169 cadelas diagnosticadas com neoplasia mamária maligna, onde foram obtidas informações quanto: avaliação das margens, localização, tamanho, apresentação clínica, grau de aderência, graduação e classificação histopatológica das neoplasias e o comprometimento de linfonodos regionais. As margens estavam comprometidas em 11 (6,5%) pacientes. As neoplasias malignas mais frequentes foram carcinoma em tumor misto (n=83; 29,64%). Pacientes com carcinoma anaplásico (n=6; 2,14%) apresentaram mais probabilidade de ter as margens comprometidas (p= 0,050), e os pacientes com adenomioepitelioma maligno (n=13; 100%), maiores chances de apresentarem as margens livres (p=0,021). Os pacientes que apresentaram os linfonodos com metástases, possuíram mais chance de as margens estarem comprometidas (p=0.041). Podemos concluir que os achados histopatológicos possuem relação com as margens cirúrgicas, enquanto os parâmetros clínicos como: localização, o tamanho, a apresentação não interferiram. Nesse estudo os pacientes acometidos com carcinomas anaplásicos apresentam uma maior chance de as margens estarem comprometidas, enquanto os acometidos por adenomioepitelioma maligno tenderam a apresentar as margens cirúrgicas livres de neoplasia.

A úlcera de córnea é uma das patologias mais recorrentes quando se trata da oftalmologia veterinária, diversos fatores podem ocasionar a ocorrência da mesma. Consiste na ruptura da membrana epitelial juntamente com o surgimento do estroma, as causas normalmente estão relacionadas com inflamações e lesões das camadas da córnea, para um diagnóstico preciso é necessário realizar além da anamnese completa e do exame oftalmológico, o teste com fluorescência. Atualmente vem sendo pesquisado e realizado, o uso de pele de tilápia como enxerto principalmente no reparo de queimaduras em humanos, e os resultados foram bem sucedidos. A pele de tilápia possui uma epiderme recoberta por um epitélio pavimentoso estratificado e extensas camadas de colágeno, o seu uso vem trazendo resultados promissores também na Medicina Veterinária. O presente artigo busca realizar uma revisão de literatura acerca dos resultados obtidos após o enxerto com pele de tilápia ter sido utilizado em intervenções cirúrgicas de reparo corneal em cães.

O maropitant é utilizado em cães e gatos como antiemético sendo sua ação antagonista nos receptores NK-1, seu ligante mais próximo o neuropeptídeo conhecido como substância P, que desempenha um papel primordial na transmissão e manutenção de informações nociceptivas, assim a inibição da liberação dessa substância é considerada uma conduta para fornecer analgesia eficaz. O objetivo deste trabalho, foi avaliar a eficácia analgésica do maropitant em duas cadelas submetidas a ovariosalpingohisterectomia.

O objetivo do estudo foi avaliar os aspectos clínicos e laboratoriais de cães com hipercortisolismo dependente do hormônio adrenocorticotrófico (ACTH) em uma série de casos (131). Predominaram fêmeas (63%), idade média de 10 anos, as raças mais frequentes foram Shih-tzu (15,27%), Poodle (14,5%) e Yorkshire (14,5%). Os achados laboratoriais mais comuns foram elevação da atividade de alanina aminotransferase (ALT) (49,56%) e fosfatase alcalina (FA) (75,65%), hipertrigliceridemia (74,34%) e hipercolesterolemia (51,72%). As manifestações clínicas mais frequentes foram poliúria (47,86%), polidipsia (54,70%) e polifagia (47%). As comorbidades mais encontradas foram hepatopatias (70,16%), alterações em vesícula biliar (66,13%) e dermatopatias (11,29%). Concluiu-se que a caracterização dos pacientes foi semelhante a estudos anteriores; porém, com uma frequência menor de manifestações clínicas, sugerindo um diagnóstico em estágios mais precoces.

O objetivo deste trabalho foi relatar o procedimento anestésico multimodal com infusão de dexmedetomidina realizado em uma cadela, SRD, 10 meses, para a cirurgia de ovariosalpingohisterectomia (OSH). Como protocolo de mediação pré-anestésica foram utilizadas, dexmedetomidina 2 mcg/kg/IM, cetamina 1 mg/kg/IM e metadona 0,1 mg/kg/IM. Após 10 minutos a paciente foi conduzida ao centro cirúrgico já com acesso intravenoso no qual foi realizada a indução com propofol 3mg/kg/IV e mantida com infusão de dexmedetomidina na dose de 0,5mcg/kg/min e na anestesia inalatória com isoflurano no vaporizador universal. Durante todo o procedimento os parâmetros avaliados foram frequência cardíaca, pressão sistólica, frequência respiratória, saturação de oxigênio no sangue periférico, pressão parcial de gás carbônico ao final da expiração, glicemia e temperatura. A avaliação foi realizada a cada 5 minutos, com exceção da glicemia que foi avaliada em quatro momentos diferentes, sendo eles pré-anestésico, trans cirúrgico e pós-operatório imediato. Os efeitos indesejados da dexmedetomidina é dose dependente, as alterações nos parâmetros fisiológicos aferidas durante o procedimento foram mínimas e foi constatado um ótimo relaxamento abdominal durante o procedimento além de uma excelente analgesia no trans e pós-cirúrgico. Sendo assim, a infusão de dexmedetomidina na dose utilizada (0,5mcg/kg/min) pode ser uma ferramenta segura no procedimento anestésico, além de promover uma rápida recuperação e uma analgesia eficiente no pós-operatório.

Tumores testiculares são comumente descritos em caninos, nos quais destacam-se o sertolioma, seminoma e tumor das células de Leydig. Tumores mistos são menos frequentes, mas podem surgir como uma associação entre células germinativas ou entre células germinativas e intersticiais. O objetivo deste trabalho é descrever um caso de tumor testicular misto unilateral em canino, destacando-se os aspectos patológicos e imuno-histoquímicos. O caso refere-se a um cão de dez anos de idade atendido no Hospital Veterinário da Universidade Federal da Paraíba, Areia, Brasil, com histórico de sangramento peniano durante dez dias. No atendimento foi constatado aumento de volume no testículo esquerdo associado a moderada hematúria, o que motivou solicitação de exames hematológicos, ultrassonografia abdominal e citologia testicular. Achados significativos foram observados apenas na citologia do testículo, que foram consistentes com sertolioma. Diante do quadro, o animal foi encaminhado para cirurgia, sendo realizada a ablação de ambos os testículos os quais foram enviados ao Laboratório de Patologia da referida instituição para avaliação histopatológica. Fragmentos dos testículos foram fixados em formol 10%, processados rotineiramente para confecção de blocos de parafina, cortados a 3µm e corados com hematoxilina e eosina (HE). Os achados histopatológicos revelaram túbulos seminíferos contorcidos constituídos por uma proliferação de células grandes, situadas perpendicularmente à membrana basal dos túbulos (Sertoli), possuindo amplo citoplasma, levemente granular, de limites distintos, e núcleo com cromatina frouxa e nucléolos únicos e evidentes. Uma segunda população era caraterizada por proliferação de células intersticiais pleomórficas, exibindo amplo citoplasma vacuolizado e núcleo discretamente excêntrico (células de Leydig), apresentavam anisocitose e anisocariose moderadas. Diante disso, considerou-se a ocorrência de um tumor testicular misto. Para a confirmação da linhagem celular foi solicitado estudo imuno-histoquímico do tumor, nos quais GATA-4, Melan A e alfa-inibina se mostraram positivos para células de Leydig e o PGP9.5 foi positivo para células de Leydig e germinativas. Através dos achados imuno-histoquímicos pode-se constatar tumor misto de células germinativas e do cordão estromal, o que diferiu do diagnóstico com a coloração usual de HE. Tumores testiculares são neoplasmas comuns na espécie canina, no entanto podem ocorrer com padrões morfológicos atípicos, constituindo desafio no diagnóstico patológico.

This study investigated the association between neurological signs as well as plausible risk factors and the seroprevalence of Toxoplasma gondii and Neospora caninum infection in dogs of the Campo Grande region of Mato Grosso do Sul, Brazil. In this study, the dogs were divided into two groups based on the presence and the absence of neurological signs (n=30 in each group). Serological diagnosis was performed using the indirect fluorescent antibody test. In the group with neurological disorders, 23.3% and 30% of the dogs had anti-T. gondii and anti-N. caninum antibodies, respectively. Moreover, three dogs from this group showed co-infection with both protozoa. In the group without neurological signs, 16.7% and 13.3% of the dogs were seropositive for T. gondii and N. caninum, respectively. Although presence of neurological signs was not associated with T. gondii and N. caninum infections (P = 0.747 and P = 0.21, respectively), there was a statistical association between T. gondii seropositivity and peripheral neurological alteration (P = 0.016) among dogs with neurological signs. Raw meat ingestion was the only risk factor associated with the presence of anti-N. caninum antibodies (P = 0.041). Results revealed evidence of exposure to N. caninum and T. gondii in dogs irrespective of the presence of neurological signs. Moreover, this study highlighted the need for serological investigation of T. gondii in dogs with disturbances in peripheral nervous systems and not offering raw meat to animals to avoid the risk of N. caninum infection. [ABSTRACT FROM AUTHOR]

The present study deals with the development of compressed air energy storage options for off-peak electricity storage, along with heat recovery options. Three cases based on compressed air energy storage are considered for investigation and compared for evaluation. While case 1 considers only compressed air energy storage, case 2 includes cascaded heat storage for useful heat output. In case 3, compressed air energy storage is integrated with cascaded latent heat storage and organic Rankine cycle for power generation. The developed systems are analyzed based on the first and second laws of thermodynamics. Results indicate that heat recovery in the air compression process has great potential to improve the system performance. Heat storage option is included in the develped systems to provide opportunity for later use. For a 12 h charging period and a 6 h discharging period, the energy efficiencies for cases 1, 2 and 3 are determined to be 30.09%, 44.92% and 33.21%, respectively. The corresponding exergy efficiencies are then found to be 30.09%, 31.15% and 33.21%. While using the heat recovered as the useful output has improved the energetic performance by almost 15%, it has increased the exergetic performance by around 1%. When there is no heat demand on the site, case 3 has great potential to store off-peak electricity. [ABSTRACT FROM AUTHOR]

Copyright of Extensão em Foco is the property of Universidade Federal do Parana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Prognóstico é definido na medicina, como uma predição baseada no diagnóstico do paciente e nas possibilidades terapêuticas, acerca da duração da enfermidade, gravidade da doença e taxa de óbito. Os índices de prognóstico utilizados em medicina humana ou mesmo os poucos padronizados para medicina veterinária não são muito difundidos ou aplicados na clínica de pequenos animais. Dessa forma, esta pesquisa objetivou identificar variáveis de uso comum na rotina clínica que possam ser úteis como marcadoras de prognóstico, se correlacionando, especificamente como o tempo de internamento (TI), gravidade de doença e mortalidade. Para tal, foram avaliados 246 cães da rotina de um hospital veterinário escola do sul do Brasil, estudados em relação ao estado nutricional (EN) (por anamnese, exame físico e laboratorial), exames hematológicos e diversos parâmetros bioquímicos séricos. Foram calculadas as frequências, médias e desvios-padrões das variáveis, análises de correlação e análises comparativas (Kruskal-Wallis em α = 5%). Foram considerados marcadores relevantes de gravidade de doença em cães: presença de desnutrição, incluindo histórico de hiporexia, anorexia, escore de condição corporal (ECC) ≤3 e escore de massa muscular (EMM≤2); baixos valores de transferrina (TF), da capacidade total de ligação ao ferro (CTLF) e anemia; além de valores elevados de índice de saturação da transferrina (IST), lactato e da relação PCR/albumina. Nos animais sem doenças sistêmicas ou com doenças sistêmicas discretas a moderadas, os indicadores de elevado TI foram: baixos valores de albumina, relação Proteína-C-Reativa (PCR)/Albumina e hiporexia. Nos animais com doenças sistêmicas críticas, os indicadores de baixo TI (secundários a alta mortalidade) foram: baixos valores de índice de massa corporal (IMC) e hemoglobina (HB). Os indicadores de mortalidade em cães doentes foram: hipoalbuminemia e elevada concentração de ureia. Conclui-se que a constatação dessas alterações, especialmente quando ocorrem simultaneamente, embasa a determinação do prognóstico em cães de uma população hospitalar, de maneira objetiva, prática e acessível.

Copyright of Arquivos Brasileiros de Oftalmologia is the property of Arquivos Brasileiros de Oftalmologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Interdisciplinar de Marketing (RIMAR) is the property of RIMAR - Revista Interdisciplinar de Marketing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Brasileira de Reprodução Animal is the property of Revista Brasileira de Reproducao Animal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Os meningiomas são neoplasias benignas que podem apresentar caráter biológico maligno devido às alterações intracranianas, e de acordo à sua localização causar compressão dos tecidos adjacentes. Estão entre as neoplasias mais comuns de sistema nervoso central em cães. Podem surgir em pacientes geriátricos e causam sintomas variáveis, dependendo da localização, extensão e taxa de crescimento. O tratamento definitivo é feito por ressecção cirúrgica e radioterapia. O objetivo desse trabalho é relatar um caso de meningioma intracraniano envolvendo o bulbo olfatório e lobo frontal esquerdos em um cão da raça Pastor de Shetland, com 10 anos de idade, encaminhado para o setor de diagnóstico por imagem para a realização de ressonância magnética após apresentar convulsões generalizadas e tetraparesia não deambulatória, bem como a escolha do protocolo anestésico e analgésico e cuidados pós-operatórios. Concluiu-se que pacientes submetidos à craniotomia devem ser submetidos à anestesia geral com protocolos seguros que considerem o procedimento cirúrgico e também às comorbidades. No pós-operatório desses pacientes se requer acompanhamento em unidades de terapia intensiva a fim de reduzir o risco de óbito e de complicações.

In the energy transition, the promotion of renewable sources entails the development of storage technologies to manage the mismatch between energy production and demand. In this scenario, the use of CAES (Compressed Air Energy Storage) technology enables the efficient and cost-effective storage of large amounts of energy. However, this technology is developed in salt domes who have an inherent risk associated of underground exploration phase. To address this, we propose to develop an infrastructure (iCAES) in abandoned underground mines, where the exploration phase is completed and well known. For its implementation, this paper defines a structure hierarchization method gathers the technical and socio-economic criteria. It involves a multi-criteria problem, and the correct selection of the location must be based on specific mathematical algorithms. For this case the Analytic Hierarchy Process (AHP) from multi-criteria decision making (MCDM) methods allows quantified by means of a scientific and mathematical scale and the assignment of weights, so that it is possible to evaluate different alternatives. This is possible thanks to the application of the AHP model in absolute terms. The information gathering has been based on the specific case study of coal basins in the north of Spain, in the region of León. Considering the proposed methodology, the most suitable alternative locations to implement iCAES in the region of León were identified.

RESUMO Objetivo investigar as habilidades comunicativas em crianças pertencentes a famílias multiespécie, nas quais o cão é o animal de estimação. Método estudo do tipo exploratório, descritivo, transversal, de natureza qualitativa. Casuística: 34 sujeitos de ambos os sexos, na faixa etária entre três meses e quatro anos e cinco meses, pertencentes a famílias multiespécie. A pesquisa foi realizada na residência dos próprios sujeitos. Procedimento: os dados foram coletados por meio de observação e filmagem de uma situação de interação, na rotina familiar, durante 30 minutos, envolvendo a presença do cão. Análise dos resultados: os dados foram analisados por meio de categorias de análises de conteúdo quanto a elementos verbais e não verbais, privilegiando as condutas comunicativas na interação criança-cão-adulto interlocutor. Resultados evidenciou-se que o cão desempenhou papel de interlocutor durante as cenas de interação com efeitos nas funções comunicativas da criança. Conclusão os resultados dessa pesquisa apontam para possíveis benefícios no que se refere às habilidades comunicativas nas interações multiespécie e sugere pesquisas posteriores.

A Síndrome respiratória obstrutiva dos braquicéfalos (SROB) é caracterizada por alterações anatômicas e fisiológicas que provocam importante obstrução das vias aéreas superiores e afetam predominantemente cães de raças braquicéfalicas. Essas alterações anatômicas podem ser classificadas em primárias, como a estenose de narina, prolongamento de palato mole e hipoplasia de traqueia, e secundárias, geralmente ocasionadas pelo aumento da turbulência e resistência ao ar, como a eversão de sáculos laríngeos, edema, inflamação da nasofaringe, paralisia e colapso de laringe. Pode ocorrer a evolução dessas alterações com a idade, desenvolvendo doenças respiratórias mais graves e até levar o paciente a óbito. O objetivo deste relato foi descrever um caso clínico cirúrgico de um canino, da raça bulldogue francês, submetido às técnicas de rinoplastia e estafilectomia. O paciente deu entrada com um quadro de dificuldade respiratória quando submetido à exercício, com dispneia, roncos durante o sono, inquietação e algumas vezes regurgitava o alimento. Ao exame físico, constatou-se ser a Síndrome braquicefálica, em que apresentava estenose de narina e estridor inspiratório, sugerindo prolongamento de palato mole. O paciente foi encaminhado para cirurgia corretiva de Rinoplastia e estafilectomia. O procedimento foi realizado, com um bom prognóstico e melhora significativa na qualidade de vida.

Power supply instability in the grid has been exacerbated by the rapid development of new energy generation methods. Notably, large-scale energy storage is the most practical solution to this problem. Meanwhile, in China, an effective method of reusing the increasing number of abandoned coal mines is urgently required. Accordingly, building compressed air energy storage (CAES) plants along the roadways of abandoned coal mines can serve as a viable energy storage method while repurposing these mines. This study examined the effect of the lower limit of air pressure (LLAP) on the stability of coal mine roadways in CAES applications by considering an ongoing pilot CAES coal mine in Chongqing, China. The findings indicate that the LLAP has a positive correlation with the roadway stability provided the frequency of air injection/extraction and upper limit of air pressure are constant. Over 10 years of CAES operation, a higher LLAP corresponds to less overall deformation of the roadway and top slab subsidence, and smaller plastic zone volume. Furthermore, the first main principle stress also decreases as the LLAP increases. According to the findings of this paper, the LLAP for the actual operation of CAES should be adjusted upwards as appropriate, which help to improve the geological stability of CAES roadways.

Geological restrictions and the low energy density of compressed air energy storage (CAES) plants constitute a technical and economic barrier to the enablement of variable and intermittent sustainable sources of energy production. Liquid air energy storage (LAES) and pumped thermal energy storage (PTES) systems offer a promising pathway for increasing the share of renewable energy in the supply mix. PTES remains under development while LAES suffers from low liquefaction unit efficiency, although it is at a higher technology readiness level (TRL) than PTES. The most significant element of large-scale EES is related to the discharge features of the power plants, especially the energy storage unit. Here, a novel multi-aspect equation, based on established codes and thermodynamic principles, is developed to quantify the required storage capacity to meet demand consistent with the design parameters and operational limitations of the system. An important conclusion of the application of the multi-aspect equation shows that liquid air storage systems instead of compressed air would reduce the space required for storage by 35 times. Finally, a cost equation was introduced as a function of the required storage volume. Calculations have demonstrated that the use of the novel cost equation, in lieu of the old one-aspect cost equation, for an LAES power plant with a production capacity of about 50 MW makes the costs of installing liquid air storage tanks against the total expenditure of the power plant about six times higher than what was reported in earlier research. [ABSTRACT FROM AUTHOR]

Objetivou-se avaliar o efeito coindutor e cardiorrespiratório da dexmedetomidina (DXD) sobre a dose de propofol para a indução anestésica em cães. Foram utilizados 24 cães machos, idade média de 2,5(±2) anos e peso médio de 10,9(±1) kg. Os animais foram pré-medicados, IM, com acepromazina e morfina, nas doses de 0,05 mg/kg e 0,5 mg/kg, respectivamente, alocados aleatoriamente em três tratamentos de indução da anestesia (n:8): GDI (DXD 5 µg/kg e propofol dose efeito); GDII (DXD 2,5 µg/kg e propofol dose efeito); ou GC (propofol dose efeito) e manutenção anestésica realizada com isoflurano. Os parâmetros cardiovasculares, foram avaliados imediatamente antes da administração do coindutor (M0), antes da administração do propofol (M1); imediatamente após a intubação (0 minutos) (M2), e aos 2 e 5 minutos após a intubação (M3 e M4), respectivamente. Utilizou-se ANOVA seguido de Dunnet para dados paramétricos, e Friedman, seguido de Kruskall-Wallis, para não paramétricos (p=0,05). A dose de propofol necessária para a indução anestésica foi de 2,64(±0,51) mg/kg para o grupo GC, enquanto para o GDI e GDII foi de 1,63(±0,37) mg/kg (p=0,0056) e 1,47(±0,52) mg/kg (p=0,0061), representando uma redução de 38,25% e 44,31% no requerimento de propofol, respectivamente. Os menores valores para a frequência cardíaca ocorreram em M1 em relação ao M0, com diminuição de 44,5% (p=0,0036) e 51,06% (p=0,0048) e 4,34% (p=0,76) para GDI, GDII e GC, respectivamente. Conclui-se que a DXD reduz significativamente o requerimento de propofol para a indução da anestesia em cães, podendo ser utilizada como adjuvante na indução da anestesia. [ABSTRACT FROM AUTHOR]