Author: "C, Nita" - Searchworks@Jio Institute Digital Library Search Results

62 results on '"C, Nita"'

1. Magnetic moments of thallium isotopes in the vicinity of magic N = 126

Author: Z. Yue, A.N. Andreyev, A.E. Barzakh, I.N. Borzov, J.G. Cubiss, A. Algora, M. Au, M. Balogh, S. Bara, R.A. Bark, C. Bernerd, M.J.G. Borge, D. Brugnara, K. Chrysalidis, T.E. Cocolios, H. De Witte, Z. Favier, L.M. Fraile, H.O.U. Fynbo, A. Gottardo, R. Grzywacz, R. Heinke, A. Illana, P.M. Jones, D.S. Judson, A. Korgul, U. Köster, M. Labiche, L. Le, R. Lica, M. Madurga, N. Marginean, B. Marsh, C. Mihai, E. Nácher, C. Neacsu, C. Nita, B. Olaizola, J.N. Orce, C.A.A. Page, R.D. Page, J. Pakarinen, P. Papadakis, G. Penyazkov, A. Perea, M. Piersa-Siłkowska, Zs. Podolyák, S.D. Prosnyak, E. Reis, S. Rothe, M. Sedlak, L.V. Skripnikov, C. Sotty, S. Stegemann, O. Tengblad, S.V. Tolokonnikov, J.M. Udías, P. Van Duppen, N. Warr, and W. Wojtaczka
Subjects: Laser spectroscopy, Hyperfine structure, Magnetic dipole moments, Theory of finite Fermi systems, Physics, QC1-999
Abstract: The magnetic dipole moments (μ) of 209Tlg (N=128) and 207Tlm (N=126) have been measured for the first time using the in-source laser resonance-ionization spectroscopy technique with the Laser Ion Source and Trap (LIST) at ISOLDE (CERN). The application of the LIST suppresses the usually overwhelming background of the isobaric francium isotopes and allows access to heavy thallium isotopes with A⩾207. The self-consistent theory of finite Fermi systems based on the energy density functional by Fayans et al. well describes the N dependence of μ for 1/2+ thallium ground states, as well as μ for the 11/2− isomeric states in europium, gold and thallium isotopes. The inclusion of particle-vibration coupling leads to a better agreement between the theory and experiment for μ(Tlg, Iπ=1/2+). It is shown that beyond mean-field contributions to μ cannot be neglected at least for thallium isotopes with Iπ=1/2+.
Published: 2024
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2. First spectroscopy of 61Ti and the transition to the Island of Inversion at N = 40

Author: K. Wimmer, F. Recchia, S.M. Lenzi, S. Riccetto, T. Davinson, A. Estrade, C.J. Griffin, S. Nishimura, F. Nowacki, V. Phong, A. Poves, P.-A. Söderström, O. Aktas, M. Al-Aqeel, T. Ando, H. Baba, S. Bae, S. Choi, P. Doornenbal, J. Ha, L. Harkness-Brennan, T. Isobe, P.R. John, D. Kahl, G. Kiss, I. Kojouharov, N. Kurz, M. Labiche, K. Matsui, S. Momiyama, D.R. Napoli, M. Niikura, C. Nita, Y. Saito, H. Sakurai, H. Schaffner, P. Schrock, C. Stahl, T. Sumikama, V. Werner, W. Witt, and P.J. Woods
Subjects: Physics, QC1-999
Abstract: Isomeric states in 59,61Ti have been populated in the projectile fragmentation of a 345 AMeV 238U beam at the Radioactive Isotope Beam Factory. The decay lifetimes and delayed γ-ray transitions were measured with the EURICA array. Besides the known isomeric state in 59Ti, two isomeric states in 61Ti are observed for the first time. Based on the measured lifetimes, transition multipolarities as well as tentative spins and parities are assigned. Large-scale shell model calculations based on the modified LNPS interaction show that both 59Ti and 61Ti belong to the Island of Inversion at N=40 with ground state configurations dominated by particle-hole excitations to the g9/2 and d5/2 orbits. Keywords: Radioactive beams, Gamma-ray spectroscopy, Isomeric decay, Shell evolution, Island of Inversion
Published: 2019
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3. On the multipole mixing ratio of the 1066 keV transition from the 0.52 μs isomer of 180Hf

Author: A. Chalil, T.J. Mertzimekis, A. Zyriliou, P. Vasileiou, N. Florea, C. Mihai, R. Mihai, C. Nita, C. Sotty, A. Mitu, L. Stan, A. Turturica, R. Mărginean, and N. Mărginean
Subjects: Nuclear and High Energy Physics, Nuclear Experiment
Abstract: The nucleus $^{180}$Hf is one of the most primary of examples of an axially symmetric prolate rotor. Combined with the presence of high-$K$ isomers, spectroscopic studies can provide important information on the nature of its single-particle levels. Precise measurements are essential for constraining nuclear models and interpreting the nature of such isomeric states. In this work, the nucleus $^{180}$Hf was populated using the proton pick-up reaction $^{181}$Ta($^{11}$B,$^{12}$C)$^{180}$Hf at beam energy of 47 MeV at Horia Hulubei National Institute of Nuclear Physics and Engineering (IFIN-HH). The spin of the 1374 keV state and the mixing ratio of the $1066$ keV transition have been measured, the latter with an increased precision compared to the previous value from literature. The presently measured spin of the 1374 keV state, currently assigned a tentative value of $(4^-_1)$, favors one of the two different values reported in the literature. The particular state constitutes the band-head of a rotational band in $^{180}$Hf. The measured multipolarity mixing ratio of the inter-band transition $1374 \rightarrow 309$ keV can provide important information for the testing and constraining of theoretical nuclear models used for the study of the intrinsic properties of $^{180}$Hf as well as its neighboring isotopes.
Published: 2023
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4. Is there a role for cough suppression techniques in the COVID‐19 era?

Author: R. O’Doherty, N. Cribben, and C. Nita
Subjects: Aerosols, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), SARS-CoV-2, business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), MEDLINE, COVID-19, Virology, Anesthesiology and Pain Medicine, Cough suppression, Cough, Airway Extubation, Intubation, Intratracheal, Humans, Medicine, business
Published: 2020
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5. Nucleon inelastic scattering cross sections on O 16 and Si 28

Author: M. Boromiza, C. Borcea, P. Dessagne, D. Ghita, T. Glodariu, G. Henning, M. Kerveno, N. Marginean, C. Mihai, R. Mihai, A. Negret, C. Nita, M. Nyman, A. Olacel, A. Oprea, A. J. M. Plompen, C. Sotty, G. Suliman, R. Suvaila, L. Stan, A. Turturica, G. Turturica
Published: 2020
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6. Prominence of Pairing in Inclusive (p,2p) and (p,pn) Cross Sections from Neutron-Rich Nuclei

Author: N, Paul, A, Obertelli, C A, Bertulani, A, Corsi, P, Doornenbal, J L, Rodriguez-Sanchez, G, Authelet, H, Baba, D, Calvet, F, Château, S, Chen, A, Delbart, J-M, Gheller, A, Giganon, A, Gillibert, T, Isobe, V, Lapoux, M, Matsushita, S, Momiyama, T, Motobayashi, M, Niikura, H, Otsu, C, Péron, A, Peyaud, E C, Pollacco, J-Y, Roussé, H, Sakurai, C, Santamaria, M, Sasano, Y, Shiga, D, Steppenbeck, S, Takeuchi, R, Taniuchi, T, Uesaka, H, Wang, K, Yoneda, T, Ando, T, Arici, A, Blazhev, F, Browne, A M, Bruce, R, Carroll, L X, Chung, M L, Cortés, M, Dewald, B, Ding, Zs, Dombradi, F, Flavigny, S, Franchoo, F, Giacoppo, M, Górska, A, Gottardo, K, Hadynska-Klek, Z, Korkulu, S, Koyama, Y, Kubota, A, Jungclaus, J, Lee, M, Lettmann, B D, Linh, J, Liu, Z, Liu, C, Lizarazo, C, Louchart, R, Lozeva, K, Matsui, T, Miyazaki, K, Moschner, S, Nagamine, N, Nakatsuka, C, Nita, S, Nishimura, C R, Nobs, L, Olivier, S, Ota, Z, Patel, Zs, Podolyák, M, Rudigier, E, Sahin, T Y, Saito, C, Shand, P-A, Söderström, I G, Stefan, T, Sumikama, D, Suzuki, R, Orlandi, V, Vaquero, Zs, Vajta, V, Werner, K, Wimmer, J, Wu, and Z, Xu
Subjects: Nuclear Theory, Physics::Accelerator Physics, Nuclear Experiment
Abstract: Fifty-five inclusive single nucleon-removal cross sections from medium mass neutron-rich nuclei impinging on a hydrogen target at ∼ 250 MeV / nucleon are measured at the RIKEN Radioactive Isotope Beam Factory. Systematically higher cross sections are found for proton removal from nuclei with an even number of protons as compared to odd-proton number projectiles for a given neutron separation energy. Neutron removal cross sections display no even-odd splitting, contrary to nuclear cascade model predictions. Both effects are understood through simple considerations of neutron separation energies and bound state level densities originating in pairing correlations in the daughter nuclei. These conclusions are supported by comparison with semimicroscopic model predictions, highlighting the enhanced role of low-lying level densities in nucleon-removal cross sections from loosely bound nuclei.
Published: 2019

7. Evolution of E 2 strength in the rare-earth isotopes Hf 174 , 176 , 178

Author: J. Wiederhold, V. Werner, R. Kern, N. Pietralla, D. Bucurescu, R. Carroll, N. Cooper, T. Daniel, D. Filipescu, N. Florea, R-B. Gerst, D. Ghita, L. Gurgi, J. Jolie, R. S. Ilieva, R. Lica, N. Marginean, R. Marginean, C. Mihai, I. O. Mitu, F. Naqvi, C. Nita, M. Rudigier, S. Stegemann, S. Pascu, P. H. Regan
Published: 2019
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8. CO_2 storage and release in the deep Southern Ocean on millennial to centennial timescales

Author: Catherine Cole, Rosanna Greenop, Laura F. Robinson, Jess F. Adkins, Joseph A. Stewart, James W. B. Rae, Andrea Burke, Tianyu Chen, Ben J Taylor, Tao Li, D. C. Nita, and Eloise Littley
Subjects: Carbon dioxide in Earth's atmosphere, Multidisciplinary, 010504 meteorology & atmospheric sciences, Climate change, Ocean acidification, 010502 geochemistry & geophysics, 01 natural sciences, Deep sea, Carbon cycle, Oceanography, Continental margin, Deglaciation, Ice age, 0105 earth and related environmental sciences
Abstract: The cause of changes in atmospheric carbon dioxide (CO2) during the recent ice ages is yet to be fully explained. Most mechanisms for glacial–interglacial CO2 change have centred on carbon exchange with the deep ocean, owing to its large size and relatively rapid exchange with the atmosphere1. The Southern Ocean is thought to have a key role in this exchange, as much of the deep ocean is ventilated to the atmosphere in this region2. However, it is difficult to reconstruct changes in deep Southern Ocean carbon storage, so few direct tests of this hypothesis have been carried out. Here we present deep-sea coral boron isotope data that track the pH—and thus the CO2 chemistry—of the deep Southern Ocean over the past forty thousand years. At sites closest to the Antarctic continental margin, and most influenced by the deep southern waters that form the ocean’s lower overturning cell, we find a close relationship between ocean pH and atmospheric CO2: during intervals of low CO2, ocean pH is low, reflecting enhanced ocean carbon storage; and during intervals of rising CO2, ocean pH rises, reflecting loss of carbon from the ocean to the atmosphere. Correspondingly, at shallower sites we find rapid (millennial- to centennial-scale) decreases in pH during abrupt increases in CO2, reflecting the rapid transfer of carbon from the deep ocean to the upper ocean and atmosphere. Our findings confirm the importance of the deep Southern Ocean in ice-age CO2 change, and show that deep-ocean CO2 release can occur as a dynamic feedback to rapid climate change on centennial timescales. Analysis of deep-sea coral boron isotope data, as a proxy for pH and thus CO2 chemistry, provides evidence of CO2 storage in the deep Southern Ocean during the last ice age, and its rapid release on millennial to centennial timescales during deglaciation.
Published: 2018
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9. CO

Author: J W B, Rae, A, Burke, L F, Robinson, J F, Adkins, T, Chen, C, Cole, R, Greenop, T, Li, E F M, Littley, D C, Nita, J A, Stewart, and B J, Taylor
Subjects: Carbon Sequestration, Time Factors, Atmosphere, Climate, Oceans and Seas, Greenland, Ice, Antarctic Regions, Carbon Dioxide, Hydrogen-Ion Concentration, Models, Theoretical, Anthozoa, Isotopes, Animals, Seawater, History, Ancient, Boron
Abstract: The cause of changes in atmospheric carbon dioxide (CO
Published: 2018

10. Structure-property relationships for Eu doped TiO2 thin films grown by a laser assisted technique from colloidal sols

Author: Constantin Logofatu, A. Pérez del Pino, Mario Borlaf, Eniko Gyorgy, Rosalía Serna, C. Nita, I. Camps, Rosa Giménez Moreno, Liviu Duta, María T. Colomer, Ministry of Education and Research (Romania), and Ministerio de Economía y Competitividad (España)
Subjects: Materials science, Photoluminescence, General Chemical Engineering, Analytical chemistry, chemistry.chemical_element, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Photocatalytic applications, Thermal-stability, X-ray photoelectron spectroscopy, Europium, Optical-properties, Evaporation maple, Thin film, Spectroscopy, Graphene oxide, Band-gap, Dopant, General Chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Absorption edge, chemistry, Nanoparticles, 0210 nano-technology, Titanium-dioxide, Oxide/graphene oxide composites, Visible spectrum
Abstract: Photoactive europium doped titanium dioxide (Eu:TiO2) thin films were grown by a matrix assisted pulsed laser evaporation technique. TiO2 and Eu cation-adsorbed TiO2 nanoparticles (NPs) sols were used as starting materials. The sols were synthesized by a colloidal sol–gel route. In order to obtain solid targets, the sols were cooled down until solidification in liquid nitrogen. The irradiation of the solid targets was performed in a controlled oxygen atmosphere using an UV KrF* (λ = 248 nm, τFWHM ≤ 25 ns, ν = 10 Hz) excimer laser source. The NPs were transferred and deposited onto solid substrates placed in the front of the frozen targets, forming continuous thin films. The as-grown undoped and Eu:TiO2 thin films were submitted to post-deposition thermal treatments. The surface morphology, crystalline structure, and chemical composition of the thin films were characterized by field emission scanning electron microscopy, X-ray diffraction, and X-ray photoelectron spectroscopy. Functional optical properties of the films were investigated by UV-VIS-NIR spectroscopy, spectroscopic ellipsometry, and photoluminescence as a function of dopant concentration in the TiO2 host and annealing temperature. A direct correlation was established between the processing conditions, films structure, chemical composition and oxidation states studied both at the top surface and in-depth as well as their functional, optical properties. Eu doping induces a blue-shift of the absorption edge with respect to the as-grown samples. Under visible light excitation (λ = 488 nm, emitted by an Ar+ laser source), the Eu:TiO2 samples show characteristic photoluminescence corresponding to the 5D0 → 7Fi (i = 0, 1, 2, 3, 4) transitions of Eu+ ions in the visible spectral range. The samples treated at the highest annealing temperature are characterized by strong photoluminescence emission, high transmittance in the VIS-NIR spectral regions, and high refractive index., The authors thank the financial support of the Executive Unit for Financing Higher Education, Research, Development and Innovation of the Romanian Ministry of Education and Scientific Research under the contract PN-III-P2-2.1-PED-2016-1043 and the Spanish Ministry of Economy and Competitiveness under the project ENE2014-56109-C3-3-R. ICMAB acknowledges financial support from the Spanish Ministry of Economy and Competitiveness, through the “Severo Ochoa” Programme for Centres of Excellence in R&D (SEV- 2015-0496). I. C. and M. B. thank the financial support of Consejo Superior de Investigaciones Científicas for PhD Grants JAE-Pre-201100578 and JAE-Pre-083.
Published: 2017

11. STRATEGI KOMUNIKASI PEMASARAN PADA BANK MUAMALAT CABANG PALOPO

Author: NITA ADELIA SARI C, NITA
Subjects: 302.2 Komunikasi
Published: 2017

12. THE SINERGY BETWEEN LASERS AND ADIPOSE SURGERY IN FACE AND NECK REJUVENATION: A NEW APPROACH FROM PERSONAL EXPERIENCE

Author: D. A. Chirita, M. Filipescu, Dana Mihaela Jianu, A. C. Nita, and S. A. Jianu
Subjects: medicine.medical_specialty, Co2 laser, Autologous Fat Graft, business.industry, Biomedical Engineering, Adipose tissue, Original Articles, Fat redistribution, Surgery, Clinical photography, medicine, Skin laxity, Dermal matrix, business, Rejuvenation
Abstract: Background and aims: Patients now want a long-lasting youthful appearance but with a minimally-invasive approach. Our unique approach, “AdipoLASER reJuvenation (ALJ)”, involves a variety of minimally-invasive laser- and lipolysis-based techniques, and the present study assessed the impact of this ALJ approach. Subjects and Methods: From 2008 — 2011, we prospectively enrolled 221 patients into the study. 71 of them, underwent the ALJ approach: 2 reductive techniques via microliposuction and laser-assisted lipolysis (LAL); and 2 regenerative techniques via autologous fat graft and fractional CO2 laser resurfacing. The remaining 150 patients underwent only 1 or 2 of these techniques. Patients were monitored through 1 to 18 months, clinical photography was taken and histological assessments were performed. Results: ignificantly better and long-lasting results were obtained for the complete ALJ approach regarding all aspects of the face, mandible and neck compared with controls. The combination of the regenerative and the reductive approaches delivered on excellent balance, restoring a youthful, natural appearance to the face. Conclusions: The fractional CO2 laser has both a photodestructive, or HLLT, effect and an LLLT component in the beam periphery. This LLLT effect possibly prolonged the life and improved the take of the fat grafts, with the well-documented HLLT effect inducing swift collagenesis and better remodeling of the dermal matrix. A natural look in depressed areas was thus restored with the combination of fat redistribution and the HLLT/LLLT effect. Microlipolysis and laser-assisted lipolysis (LAL) could at the same time remove those areas of redundant and prolapsed fat while countering skin laxity, and address both jowl formation and submental flaccidity. The unique combination of all four approaches in our “AdipoLASER reJuvenation” proved to be superior to any other lesser approach in both the long- and short term with very little patient downtime, but did not present much more in terms of treatment time and cost to the patient. We believe that the ALJ approach offers a real minimally-invasive alternative to the classic surgical facelift
Published: 2012
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13. Adiponectin predicts cardiovascular events in diabetes dialysis patients

Author: C. Nita, Crina Rusu, Ioan Mihai Patiu, Anca Rusu, Gabriel Kacso, Simona Racasan, Remus Moldovan, Dan Vladutiu, Alina Potra, Diana Moldovan, Cosmina Ioana Bondor, Remus Orasan, B. Ghigolea, Ina Maria Kacso, and C. Spanu
Subjects: Male, medicine.medical_specialty, medicine.medical_treatment, Clinical Biochemistry, Population, Adipokine, Kaplan-Meier Estimate, Gastroenterology, Cohort Studies, chemistry.chemical_compound, Renal Dialysis, Internal medicine, Diabetes mellitus, medicine, Diabetes Mellitus, Humans, education, Proportional Hazards Models, education.field_of_study, Adiponectin, Cholesterol, business.industry, Hazard ratio, General Medicine, Middle Aged, medicine.disease, Atherosclerosis, Endocrinology, Treatment Outcome, chemistry, Cardiovascular Diseases, Multivariate Analysis, Uric acid, Regression Analysis, Female, Hemodialysis, business
Abstract: Objectives Adiponectin is an insulin-sensitizing, anti-inflammatory adipokine with anti-atherogenic actions in the general population. In dialysis patients it is unclear whether adiponectin conserves its protective value or is, on the contrary, associated to worse prognosis. We assessed the predictive value of adiponectin for atherosclerosis related cardiovascular events in type 2 diabetic dialysis patients. Design and methods Prevalent diabetic dialysis patients from three dialysis units (n = 77) were enrolled in a 3 years' prospective observational study. Serum adiponectin, clinical and laboratory parameters were determined at baseline; new occurrence of atherosclerosis related events (coronary events, atherosclerosis obliterans, and stroke) was recorded. Results Baseline adiponectin was 17.25(9.53–31.97) μg/mL and significantly correlated to HDL cholesterol (r = 0.29, p = 0.01), triglycerides (r = −0.40, p = 0.0004), ferritin (r = − 0.29, p = 0.02), transferrin (r = − 0.28, p = 0.02), and uric acid (r = − 0.24, p = 0.04). In multivariate analysis association to triglycerides (p = 0.001), HDL cholesterol (p = 0.01) and ferritin (p = 0.04) remained significant. 36 new fatal and non-fatal new cardiovascular events occurred, 29 patient died. Cox proportional regression analysis showed that adiponectin below or above a ROC-derived cut-off of 27.33 μg/mL significantly influenced event-free survival: hazard ratio (HR) 2.48, 95% confidence interval (CI) (1.09–5.66), p = 0.031 along with fasting glucose HR 1.01, 95%CI(1.00–1.02), p = 0.01 and history of cardiovascular events at inclusion HR 3.16, 95%CI(1.36–7.32), p = 0.007. In multivariate analysis baseline adiponectin HR 5.02, 95%CI(0.98–25.06), p = 0.05 and glycemia HR 1.01, 95%CI(1.00–1.02), p = 0.01 influenced event-free survival. Adiponectin also predicted cardiovascular events in patients without cardiovascular disease at inclusion but was not associated to overall mortality. Conclusions In diabetes dialysis patients low adiponectin favors occurrence of atherosclerosis related cardiovascular events.
Published: 2015

14. First Experimental Tests of the Modernized VASSILISSA Separator

Author: K. Rezynkina, A. I. Svirikhin, O. N. Malyshev, S. Ntshangase, J. Piot, A. Lopez-Martens, A. V. Isaev, P. Jones, A. N. Kuznetsov, A. G. Popeko, B. Andel, M. L. Chelnokov, Elka Stefanova, A. V. Yeremin, J. Gehlot, S. Mulins, B. J. P. Gall, F. Dechery, A. V. Belozerov, E. A. Sokol, A. A. Kuznetsova, V. I. Chepigin, K. Hauschild, D. Tonev, F. Le Blanc, C. Nita, O. Dorvaux, D. Pantelika, CSNSM SNO, Centre de Spectrométrie Nucléaire et de Spectrométrie de Masse (CSNSM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)-Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Grand Accélérateur National d'Ions Lourds (GANIL), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Design phase, Nuclear physics, Physics, Nuclear and High Energy Physics, Radiation, Nuclear magnetic resonance, Recoil, Radiology, Nuclear Medicine and imaging, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Atomic and Molecular Physics, and Optics, Separator (electricity), Ion
Abstract: International audience; The results of the first experimental tests of the modernized VASSILISSA separator with the useof accelerated 22Ne ions are presented. Data has been obtained on the transmission coefficients of recoilnuclei synthesized in asymmetric combinations of the incident ion and target nuclei. Estimates from ion optical calculations performed in the design phase of the project of modernizing the separator are completelyconfirmed.2015
Published: 2015
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15. Thermal and fluid simulation of the environment under the dashboard, compared with measurement data

Author: G M Sirbu, I C Nita, and Cristian Sorin Popescu
Subjects: Natural convection, business.industry, Computer science, 020209 energy, 02 engineering and technology, Computational fluid dynamics, Heat sink, Automotive engineering, Reliability (semiconductor), Thermal, 0202 electrical engineering, electronic engineering, information engineering, Dashboard, Electronics, business, Simulation, Test data
Abstract: The development of vehicles during the last decade is related to the evolution of electronic systems added in order to increase the safety and the number of services available on board, such as advanced driver-assistance systems (ADAS). Cars already have a complex computer network, with electronic control units (ECUs) connected to each other and receiving information from many sensors. The ECUs transfer an important heat power to the environment, while proper operating conditions need to be provided to ensure their reliability at high and low temperature, vibration and humidity. In a car cabin, electronic devices are usually placed in the compartment under the dashboard, an enclosed space designed for functional purposes. In the early stages of the vehicle design it has become necessary to analyse the environment under dashboard, by the use of Computational Fluid Dynamics (CFD) simulations and measurements. This paper presents the cooling of heat sinks by natural convection, a thermal and fluid simulation of the environment under the dashboard compared with test data.
Published: 2017
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16. Fat graft, laser CO₂ and platelet-rich-plasma synergy in scars treatment

Author: A C, Nita, O A, Orzan, M, Filipescu, and D, Jianu
Subjects: Adult, Male, Adolescent, Platelet-Rich Plasma, preadipocyte, Middle Aged, fat graft, scar, Case Presentation, Cicatrix, Young Adult, Humans, Female, Laser Therapy
Abstract: Rationale: Many treatments have been proposed for cosmetic or functional improvement of scars. It is known that fat grafts and laser treatment can have beneficial effects on the remodeling of scar tissue, and platelet-rich plasma (PRP) can be effective during the wound-healing process. We hypothesized that laser and PRP can enhance fat graft survival and the combination would be effective in improving scars appearance. Objective: The purpose of this study was to evaluate the efficacy of these combinations in the treatment of atrophic and contractile scars. Methods and Results: From 2008-2013, we treated with this combination 64 patients affected by atrophic and contractile scars involving different body parts. At 6 months the patients’ overall satisfaction rate was excellent for over 50% of the patients. Discussion: The association of an ablative laser CO2 with PRP and autologous fat graft seems to be a promising and effective therapeutic approach for atrophic and contractile scars. Abbreviations: PRP platelet-rich plasma, OTI orotracheal intubation, HLLT high level laser therapy, LLLT low level laser therapy
Published: 2013

17. Study of16O(12C,α20Ne)α for the investigation of carbon-carbon fusion reaction via the Trojan Horse Method

Author: R. G. Pizzone, M. La Cognata, L. Trache, G. G. Rapisarda, Z. Hons, C. Bordeanu, G. Velisa, J. Mrazek, C. Spitaleri, S. Romano, Tamás Szücs, D. Pantelica, C. Nita, A. Tumino, H. Petrascu, and G. G. Kiss
Subjects: Physics, History, Reinforced carbon–carbon, chemistry.chemical_element, Trojan horse, Computer Science Applications, Education, Nuclear physics, Stars, Cross section (physics), Low energy, chemistry, Nuclear fusion, Carbon
Abstract: Carbon-carbon fusion reaction represents a nuclear process of great interest in astrophysics, since the carbon burning is connected with the third phase of massive stars (M > 8 M☉) evolution. In spite of several experimental works, carbon-carbon cross section has been measured at energy still above the Gamow window moreover data at low energy present big uncertainty. In this paper we report the results about the study of the 16O(12C,α 20Ne)α reaction as a possible three-body process to investigate 12C(12C,α)20Ne at astrophysical energy via Trojan Horse Method (THM). This study represents the first step of a program of experiments aimed to measure the 12C+12C cross section at astrophysical energy using the THM.
Published: 2016
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18. In the footsteps of Dorothea Bate: Coastal caves of Mediterranean islands and dwarf mammalian fauna

Author: D A Richards, V L Herridge, A M Lister, D C Nita, J-L Schwenninger, K E H Penkman, E J Rhodes, R Grün, G Iliopoulos, G Mangano, L Bonfiglio, and G Insacco
Published: 2012
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19. Constraining sea level change at the end of marine isotope stage 5 using high-resolution sub-samples of a Bahamas flowstone

Author: D A Richards, P L Smart, D C Nita, G E Moseley, D L Hoffmann, and R L Edwards
Published: 2012
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20. Low plasma adiponectin levels predict increased urinary albumin/creatinine ratio in type 2 diabetes patients

Author: Gabriel Kacso, M. Gherman Caprioara, Alina Ramona Lenghel, N. Hancu, Ina Maria Kacso, Crina Rusu, Cosmina Ioana Bondor, Diana Moldovan, and C. Nita
Subjects: Male, medicine.medical_specialty, Time Factors, Urology, Renal function, Type 2 diabetes, urologic and male genital diseases, Kidney Function Tests, Body Mass Index, chemistry.chemical_compound, Internal medicine, medicine, Albuminuria, Humans, Diabetic Nephropathies, Prospective Studies, Creatinine, Proteinuria, Adiponectin, Visual test, business.industry, nutritional and metabolic diseases, Middle Aged, medicine.disease, Prognosis, Endocrinology, chemistry, Diabetes Mellitus, Type 2, Nephrology, Disease Progression, Microalbuminuria, Female, medicine.symptom, business, Follow-Up Studies, Glomerular Filtration Rate
Abstract: Experimental studies have shown that adiponectin has antiproteinuric and nephroprotective effects. The purpose of the study was to assess the value of plasma adiponectin as a predictor of proteinuria in type 2 diabetes (T2D) patients.In this one-year prospective follow-up study, we included T2D patients with positive visual test for microalbuminuria (Micral) and negative visual test for proteinuria. Exclusion criteria were: glomerular filtration ratio (GFR)30 ml/min, acute infection/inflammation, uncontrolled hypertension, and atherosclerotic complications. The main outcome measure was the change in urinary albumin/creatinine ratio (UACR) after 1 year follow-up (Δ UACR).Fifty-six patients (66% males) completed the study. Their initial mean UACR was 81.58 ± 26.42 mg/g and mean GFR was 81.15 ± 3.96 ml/min. At baseline, simple regression disclosed significant correlations between UACR and plasma adiponectin (r = 0.54, P = 0.00002) and GFR (r = -0.28, P = 0.03); in multiple regression analysis, plasma adiponectin remained the only predictor of UACR (P = 0.00007). Baseline plasma adiponectin was significantly correlated to body mass index (r = -0.28, P = 0.04), waist circumference (r = -0.27, P = 0.05), HDL cholesterol (r = 0.35, P = 0.01), and LDL cholesterol (r = 0.27, P = 0.04). Baseline plasma adiponectin significantly correlated in simple (r = -0.38, P = 0.004) and multiple regression (P = 0.04) to Δ UACR. When patients were divided according to Δ UACR in nonprogressors (Δ UACR0) and progressors (Δ UACR0), logistic regression showed that baseline GFR (OR = 1.04, CI95%: 1.00-1.09, P = 0.04) and plasma adiponectin (OR = 1.16, CI95%: 1.02-1.32, P = 0.02) were the only factors that predicted whether the patient would be a progressor or not.In T2D patients, lower plasma adiponectin levels seem to be predictive of increased UACR.
Published: 2011

21. Gene symbol: GLA

Author: Costel, Spanu, R H, Lekanne dit Deprez, J E M, Groener, and C C, Nita
Subjects: Family Health, alpha-Galactosidase, Mutation, Fabry Disease, Humans
Published: 2007

22. PMU Data Characterization and Application to Stability Monitoring

Author: C. Hoffmann, Thomas J. Downar, Mark R. Bell, Lefteri H. Tsoukalas, C. Nita-Rotaru, Rong Gao, A.P.S. Meliopoulos, George J. Cokkinides, Edward J. Coyle, and Oleg Wasynczuk
Subjects: Lyapunov function, Engineering, Computer science, business.industry, Real-time computing, Control engineering, System monitoring, Stability (probability), Field (computer science), symbols.namesake, SCADA, symbols, Global Positioning System, Transient (oscillation), Instrumentation (computer programming), business, Energy (signal processing)
Abstract: This paper provides a methodology to characterize the accuracy of PMU data (GPS-synchronized) and the applicability of this data for monitoring system stability. GPS-synchronized equipment (PMUs) is in general higher precision equipment as compared to typical SCADA systems. Conceptually, PMU data are time tagged with precision better than 1 microsecond and magnitude accuracy that is better than 0.1%. This potential performance is not achieved in an actual field installation due to errors from instrumentation channels and system imbalances. Presently, PMU data precision from substation installed devices is practically unknown. On the other hand, specific applications of PMU data require specific accuracy of data. Applications vary from simple system monitoring to wide area protection and control to voltage instability prediction and transient stability monitoring. The paper focuses on the last application, i.e. transient stability monitoring. We propose an approach that is based on the energy functions (Lyapunov indirect method). Specifically, we provide a methodology for determining the required data accuracy for the reliable real time estimation of the energy function. When the data meet these requirements, the estimated energy function can be visualized and animated providing a powerful visual tool for observing the transient stability or instability of the system.
Published: 2006
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23. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

Author: S. Artigas, A V Dreval, Mark I. McCarthy, C Watson, Peter H. Bennett, M Quint, Y Ikeda, E Alpert, F Schiele, H Sekihara, Erik Gylfe, P Lowe, J Kuhlmann, Alain Golay, V Longo, Shahidul Alam Khan Akm., L G Mantovani, M Zawodniak-Szalapska, G Winkler, T Harrity, L Virág, U Johne, Kuo S-W., Linda C Tapsell, J Rodriguez, Michel Komajda, K Kankova, Carole A. Cull, M Sporna, E Estilles, U Ribel, M C Spruce, E Buzzigoli, T Prazak, J K McLaughlin, M K Lingohr, M Lim, F Calara, A Siebenhofer, G Meregalli, Roberto Anichini, A D Baron, R Kurashvili, P C Butler, G I Fantus, T. E. De Gooyer, Park Y-M., R. Walther, S Heinrich, Agnieszka Zawiejska, S Mukherjee, Nikolaos Papanas, G Wong, Ian D. Caterson, David M. Maahs, Shuichi Kaneko, Alexandra E. Butler, Francisco Javier Ampudia-Blasco, O N Kong, Attali J-R., C A Hedman, K Oshinyemi, Nicolle Müller, I C Cranston, N Okumus, M V Vlaiculescu, Balasubramanian Ravikumar, W W Cheatham, K Mukasa, K B Biswas, Annunziata Lapolla, Phil McEwan, G Mader, Gilles Chassot, Dragi Anevski, Werner A. Scherbaum, M Donath, C Hesselmann, R A Gandhi, David E. Moller, Ezio Bonifacio, C Garcia, V Ifandi, P Hornnes, Nieuwenhoven Fav., C Puech, S Pérez-Del-Pulgar, Kim S-R., G Hines, C Rubio Terrés, Michael Gaster, N. Hosszufalusi, A Scholze, Andrew A. Young, Stavros Liatis, F Hariri, S Tan, Paul Valensi, Allan E. Karlsen, J Kim, E. Moberg, J Kaiser, L Berman, G Nelson, A Altkrüger, P Kothare, D B Cook, S Doran, G. van Dijk, Shahnaz Shahinfar, Kim C-S., P Stahl, M Manousaki, S Sigrist, S K Lim, M. P. Stern, A Guberti, C Rezzani, J McKenney, Karl Thomaseth, Sofia Carlsson, M Julia, R Brillante, I Rubesova, T Darkow, E Matsumoto, Wendy M. Macfarlane, M Di Martino, G Bardini, Rossella Menghini, D Duhot, E Farcasiu, Annalisa Natalicchio, I Lindner, J Buvat, Christian L. Brand, Harry Dorchy, Iwona Pietrzak, Z T Luo, P Home, M Ekelund, Jesper Gromada, Kristine Færch, F Piarulli, H Kim, R Mentel, Zsuzsanna K. Zsengellér, Dullaart Rpf., Anton Luger, Thomas A. Pearson, V Manicardi, P Rösen, Feng Y-M., R Morganti, Lars Hansen, Demuth H-U., Haruo Kasai, A Shostak, Rudi Steffensen, G Taylor, Markolf Hanefeld, C Santini, E Hamaguchi, Roberto Miccoli, F Storms, M Cooper, Y Lee, Allison E. Aiello, P Smith, T Suehiro, K Treece, M Waluś, Timothy A Welborn, Simone Baltrusch, E Kontela, S Chai, J Crean, H Yokoyama, Johan G. Eriksson, Rafael Hernández Hernández, J Rodríguez-Saldaña, M P Tornero, G Formoso, D. Lovell, E Bingham, A Mylonakis, M Manteghetti, D Fedele, Antonio Martín-Duce, Ralph A. DeFronzo, D Salcedo, Kurt Højlund, Antonio Petrone, Sheu Whh., C Gutierrez, Flavia Pricci, S Kurita, Z G Abbas, M M Benedetti, Philippe A. Halban, Daniel J. Cox, O Ljungkvist, Justine Davies, J Palsgaard, Lars Sjöström, E Bosi, L Janin-Manificat, W. F. Kelly, M. Fernandez, E Colak, O V Mulyarchik, B Kronshage, F Lang, M Erfurth, Takashi Kadowaki, N Jendrike, U Walter, J Wishart, Y. Neye, D Kim, N Furuhashi, M Barsotti, D Florow, L Ke, L Borgquist, N C Jackson, Ffolliott M. Fisher, V Baskar, K Yoshioka, Bryan A. Wolf, G Chabrier, R Skoumal, Livio Luzi, H Kose, I Pharisien, B. Klein, H Winiarska, M C Johnson, L Griffiths, Nonna Kravchun, C Combe, Baptist Gallwitz, J Zdychova, L Skorda, Jorma Ilonen, W Gao, I N Steen, A Terrinoni, P D Ambery, W Kern, C M Kusminski, Cho M-H., Paolo Pozzilli, Louise G. Grunnet, E Schönle, David R Matthews, Robert W. Taylor, Y Cohen, Kim H-S., M P Eccles, N B Tutuncu, D McDowell, Richard M. Bergenstal, K Takamatsu, T Steiner, Jaan Palgi, Valdemar Grill, N Niculescu, G Federici, S Lehto, P. M. McKeigue, M Barone, Michael E. Trautmann, S Smirnov, J Mannion, M Eto, C Rousseau, M Conti, C S Ernest, Antonio Ceriello, D H Schweitzer, Jung E-D., Andreas Festa, Avijit Lahiri, A Shepelkevich, A Murro, A Kollmann, Jonathan R.S. Arch, R Landgraf, Son H-Y., I Engelsberger, E Agardh, S Rodríguez-Mulero, P J Kraml, K Lee, D. F. Du Toit, E Kim, G Fadini, Williams Ajk., Philip Home, M B Antcieferov, C Perlemoine, D Perrea, Song X-L., D Ruggieri, Krister Bokvist, Heidi Sørensen, Bilbao, G Yoshino, J P Taylor, Shen H-M., S M Furier, R Urquhart, J Wohlgelernter, Jianping Weng, T. Baba, Q Hong, C Silva, Castaigne J-P., M Felaco, X X Zhang, M Jaroň, Milla Rosengård-Bärlund, J G Papp, Toshio Miyata, Lervang H-H., Park M-K., I Kinalska, A Long, Oomen Phn., N Kogawa, Ippolita Patrizia Patera, S. Karadeniz, Dinesh Selvarajah, D S Chung, A Wensaas, Richard Imrich, M Recasens, J Ruxer, O Buchea, E Wilpart, S P Stepanenko, Le Ttd., H Ohgawara, Mariaconsuelo Valentini, A Mondok, M Peltonen, Marianne O. Larsen, K Chatzianagnostou, Agneta Ståhle, A L Ferrari, L Bordier, F Maingrette, A Matsuda, G Vukomanovic, Jakob D. Wikstrom, T Yamakita, E Gorostiaga, J Jin, B Gopalan, Heinz Drexel, S Hewitt, Rury R. Holman, C Dieterle, T L Ruchti, N Asatiani, M Sidira, A Iezzi, A J Sommerfield, D Châtenet, M L Olsen, R Bergemann, C Koehler, T L Kuraeva, B Balas, Christian Berne, E Santos-Mazo, G Smith, A Siejka, R Kožnarová, A Mattina, S Sheikh, A Adomeit, M Rasmussen, J. Fagerudd, N Busciantella Ricci, Nuria Vilarrasa, E Hammar, T L Thoms, L Aydın, Ron G. Rosenfeld, A Nikolajuk, R Gos, C L Morgan, H L Yu, D Dheelchand, S Ramrath, N Boudriga, Jerome I. Rotter, C Jahannault, W M Weston, Folke Lindgärde, M Hertlova, D Knight, A Monroy-Mayorga, E Pardini, A Chamson-Reig, B Franke, Janie McCluskey, Joseph Bryan, C Nikolopoulou, Christie M. Ballantyne, Fausto Santeusanio, L Pegoraro, M Lee, A Klimenko, S Jaiveer, K. Pettersson-Fernholm, Michael A. Nauck, A Ekbom-Schnell, G Deferrari, Riccardo Schiaffini, S. Pampanelli, Khan Aka., David Hopkins, Maija Wessman, M Kamarinos, Noh J-H., O Ebisui, K McCarroll, Jeppe Sturis, Peter Nowotny, N Gorbenko, Åke Sjöholm, David G. Maggs, A E Halseth, B Cresci, A A Ortiz-Gress, A Korakovouni, O Matejkova, C E Mogensen, C J Lin, Ramon Gomis, H Seaman, C Granier, Yang C-H., F Assah, O Sanchez, Fausto Machicao, Peter G. Morris, Alberto Ortiz, A Giardinelli, D Bracaglia, A Gonzalo, S Pavlatos, Andreas Lechner, F Canovic, L Sjolind, Allan Vaag, Birgitte Bruun Nielsen, David A. Ziegler, Vito Lampasona, R Gershoni-Baruch, A. Dei Cas, H Renz, E Mena, Matthew Waltham, Kim D-M., H Levanen, D D Mick, Valentina Alexandrovna Peterkova, E Meskhishvili, Sarah Nutland, R Bustani, John R. Lindsay, M Christoforidou, A Abicht, E Harno, K Cyganek, A Fitchet, S Neelotpol, P Nikishin, P Serradas, J Hinrichsen, M Halvorson, M Chovatia, B Voet, Jinny Willis, E Parretti, M Haslbeck, M Wellard, L Teng, Julio Wainstein, J S Fischer, K. Lalic, D Roggenland, I Gich, R Anwar, Maurizio Cassader, D Serota, X J Li, R J Schotzinger, Vilmundur Gudnason, Björn Zethelius, S A Wootton, W Andrzejewski, R Rezsohazy, R Gao, T Klimentova, T Mazurek, I Bruckner, C Dohrmann, R E James, G daSilva Xavier, Kim S-Y., A Dorca, Stuart J. Pocock, Terri J. Allen, I Giovos, P B Parab, N H Andersen, P Fotinakis, Miriam Cnop, H Lee, Norbert Tennagels, Omorodola I. Abatan, F Ailett, I. Lager, D Manzella, H Hut, Larry A. Distiller, G Lip, Lim S-K., Rong Zhang, T Tsuno, Steen Knudsen, M. Bajardi, Manuel Benito, Dai Sugimoto, Melvin J. Prince, D W Dunstan, D Rankins, K A Majali, G Ozansoy, Isabella Russo, S Uçak, G Annuzzi, R Talar-Wojnarowska, K Lange, S Neugebauer-Baba, Campbell H. Thompson, Eric Renard, P. D. Mountjoy, Z Morrison, Elizabeth A. Davis, Franco Cavallo, C Corvaja, R Antuña, Craig John Currie, H Linnebjerg, He Y-L., A J Palmer, Mariola R. Chacón, H Malinska, M. Jones, R Lichnovská, K Mandes, Paolo Tessari, T Mokhort, A Laina, H. L. Y. Chan, I Schmidt, R Banks, Richard G. IJzerman, L Ksinantova, G Setti, H Vaudry, A Gallo, V Spallone, Chen J-W., Thomas Danne, A Chong, M Hallschmid, S Aczel, S Hulme, N Islam, M Hosoi, P M Ternan, P Di Bartolo, N Bishara, T Shibasaki, Martin A. Osterhoff, Im S-S., M Jecht, T Hamaguchi, S Mattera, K Ways, Elizabeth Northam, U Rajala, Reinhard W. Holl, L Yang, S Panaiotopoulos, K Horvath, R Kluge, Thora B. Bodvarsdottir, Y Dong, Irene Alemanno, C McDougall, Reimar W. Thomsen, M Campbell, W Rabl, John Öhrvik, Yuichiro Yamada, Paola Ungaro, W Benzer, Mike Sampson, Roberto Trevisan, R G Radu, Aas A-M., P E Lobo, Ricardo Scott, S M Son, Josephine M. Forbes, T A Hillier, K L Wyne, Louis L. Nguyen, J Farmer, M H Tan, Kwon H-S., J Yang, L Sandvik, Franco Folli, A K Jenum, M Nguyen, W Pratipanawatr, A L Frederiksen, Rebecca Smith, Lee H-J., A Schäfer, C Manuelli, G S Denver, T Vukovich, B Maceira, K Matsumoto, K. Chokkalingam, Nurcan Üçeyler, P Modi, Timothy M. Morgan, S Mertens, B M Singh, Michaela Riedl, K Iso, C Cucurullo, G. F. Bottazzo, M Calvani, K Hur, J Wetzels, Kazuhiro Takahashi, Y Aso, H Stammer, M G Masding, Fitsum Guebre-Egziabher, J L González-Sánchez, L Armstrong, Alberto Maran, Peter G.F. Swift, S S Popovic, J Starczynski, E Vitacolonna, Luigi Laviola, R W Gelling, Marina Cardellini, D Barilla, Rosa de Diego Martínez, W H Landschulz, Anne Mette Rosenfalck, R K Wong, Kevin E. Schneider, K Peros, Giuseppe Nanni, F Zhang, I Rákóczi, T Iburi, M Nakhjavani, X Q Zhang, S Tournis, Per Lav Madsen, Graham A. Hitman, A. Tura, K Laubner, N D Kostic, Lawrence M. Dolan, R. Sinha Roy, J A Wagner, J. Tuomilehto, J Hauptman, M Abdel-Ghany, D Lacombe, Toralph Ruge, Johannes A Maassen, Triantafyllos Didangelos, K Sasaki, I Argüelles, Klaus Levin, C Popow, Emanuel Christ, R Chetty, L Baillet-Blanco, Jo-Ann Salmon, T Mine, James L. Trevaskis, I Franke, J Gorski, E A Andrianova, A Dayan, A Caballero, Aleksandra Gilis-Januszewska, M Yasujima, Z Kasalová, C.D.A. Stehouwer, F. K. Gorus, G A Nichols, A Glowania, David P. Strachan, P Fredlund, N. F. da Silva, P Reboldi, M Sausbier, K H Groenier, G Stuccio, N Guttman, K R Ahmed, A D Ristic, T Kapellen, J Coutcher, Aldo V. Greco, Oswald Wagner, A Zagayko, Maria Alevizaki, B B Zhang, W F Ferris, Jenny Fredriksson, Lois Jovanovic, J Hänninen, R De Giglio, Kazuo Yagui, O Potterat, P Hamliton, R E Scranton, B Mankovsky, A Stylianou, B Fellström, Abdel-Wahab Yha., M Kitagawa, Katherine L. Baldock, F R Johnson, F Baigts, S D'Addato, F J Sanz, A Mistry, S D Wise, T Pratipanawatr, U R Fölsch, James R.C. Parkinson, Claudia Sommer, C Park, F E Griffiths, M L Martí, R Demirtunc, S Taniguchi, J Lundkvist, T Siegmund, Juan Sztajzel, C Dienesch, F Baumgartner, L Scalone, T M Mckolanis, K Otake, Ullrik Pedersen-Bjergaard, T M Vriesendorp, Michael B. Wheeler, Henry Schmitt, Peter Hovind, S Lange, Stephane Roze, L. Van Gaal, B Klaproth, Anthony E. Civitarese, D Eckland, A Dagar, D F Hopkins, Kari Stefansson, C Gonzalez-Yanes, B Meyboom-de Jong, D. J. Betteridge, K Buhling, M Crepaldi, Ana M. Wägner, L Renna, L Volpe, R McBride, V Corbo, E O Brennesvik, R P Hayes, R Abdollahnia, G Viviani, C F Liew, Francisco Pérez-Bravo, Jeffrey Baron, Brian M. Frier, H H Samira, D Szentendrei, K. J. Schjoedt, W K Waldhäusl, D Gniuli, D Zou, G Tschank, V Urbančič, A L Nolan, Albertini J-P., J Malcomson, M Larbig, C Cheyssac, K Aurich, C M Kesson, S Heller, Maija E. Miettinen, R F Luco, Adrian J. Cameron, Luigi Mattiello, Z. Metelko, X E Zhang, M Parramón, I. G. 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Thornalley, A Chaidaroglou, K Miura, B Zinman, O M Dvoynishnikova, J Plank, Jan Bolinder, C Lush, B Rubi, R Pozzilli, M Bashir, S A Shtandel, F Mosca, A Naskalska, Josef Vcelak, U Sausbier, P Cavaiani, T U Baehring, Michele Solimena, P Formisano, M Rastaldi, Bernard Thorens, J Ruzzin, E Arbit, M. Hori, Torkel B. Brismar, E Soltes Rak, A Filo, P Heinke, Matthew P. Coghlan, M Masotti, I Perevozskaya, K Ahn, I Moules, K Van Dyck, I Goldstein, Z Mathe, G Z Zhao, S Fajardo, J Taylor, S Chrul, J C Pareja, D Hadjidakis, A J Scheen, N Siddiqua, D C Cavan, R Grella, Krabbe S, H J Rochlitz, A E Hinkkanen, W Wilpshaar, Richard Stevens, M Dreyer, S Hara, X Wang, Melania Manco, D Gillen, Magalie A. Ravier, Olli Simell, John C. Lawrence, Kohnert K-D., Agardh C-D., A Berghold, L Kristensen, Grant Sfa., N Gursoy, Leif Groop, N Freemantle, Anja Schweizer, L Pala, Legros J-J., C. Di Pietro, N. Yamamoto, J Magyar, B Nikolovski, H Ikeda, D Lee, Bruce A. Buckingham, A O Wollitzer, I Kennedy, C Ernest, Neville H. McClenaghan, S Tanaka, Asimina Mitrakou, T Heinze, W Kerner, Moeenaldeen Al-Sayed, Charles Thivolet, L Klaff, A Miconi, Cristina Valeri, J. O. Christensen, K. Ekberg, A Jardine, T Endo, X Zhang, D F Child, A Kienitz, D K Seidel, H. Tada, Sylvie Abouna, Cyrus Cooper, Catherine R Chittleborough, Roberta Assaloni, S Corbi, A K Bose, K Ozawa, C Ahn, K A Deans, G Jackowski, Martin Gibson, Patrick McElduff, O A Mojiminiyi, Manuel Serrano-Ríos, O Dupuy, A L Davydov, Iwar Klimes, Sten-Anders Ivarsson, N Ichino, R Matsutomo, E R Smith, A Stefanovska, B Dehmel, K Koniavitou, E Agascioglu, M Hatazaki, J. M. Gibson, T Yada, P Ribaux, M Rupnik, K Fridell, G Scutaru, L Chugunova, Henrietta Mulnier, A Kendereski, H Lehnert, C Billi, M Sobczak, Francisco M-Mj., L K Archibald, S Sukumvanich, David B. Dunger, I. Benke, G Yillar, N Stingemore, J. M. Boavida, Y Shi, Jimmy D. Bell, L Bozzetto, Andrew J. Ahmann, E Jebens, J Keiding, Elena Henkel, Mark Fineman, J F McRae, Carol Forsblom, S Martemucci, Lourdes Ibáñez, P G Prieto, L Ringholm Nielsen, S Pratas, B von Stritzky, Julio Rosenstock, Lee K-W., J Stocks, L J Strow, I Samarguliani, L Wennekes, R Cheung, Abhishek Nag, Roberto Gambino, Y Suleymanoglu, E Murphy, T T Durck, M F Peyrot, Y Unno, Alexander Mayorov, Eleuterio Ferrannini, D. C. Rao, D Neely, H Karunajeewa, J Palmisano, Julia B. Lewis, M Ravid, G Pons, E Junca, P Vexiau, S Sailesh, D K Miloslavskiy, O N Bondarenko, U Smith, S Torri, Constantine Tsigos, Cesario Bianchi, Mattia Locatelli, D Jaquet, Virpi Lindi, M Moroi, M E Tushuizen, P Pelicci, R Scognamiglio, Pal Pacher, S M Thyssen, A Péterfalvi, Y Ho, S Guntram, L Romics, T Nakagami, Clive S. Cockram, Irina Kowalska, K Brodbeck, Gojka Roglic, J. Dörig, Lise Tarnow, Therese Tillin, A López-Alba, Martin Krššák, Moses Elisaf, S Hata, D P Snoeck, D Schmoll, O V Udovichenko, A Scaramuzza, J Paul, John H. 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Jensen, A D'Avanzo, J Monaghan, K P Yeo, Guivarch P-H., B Bauduceau, D Weghuber, P Tatti, J Ybarra, S Gwozdziewiczová, E Gasparini, B Saltin, Charlotte Granhall, Howard Leventhal, R Marin, M Tumiati, Cicero Afg., L Csémy, B Berger, S Mikros, D Dall'Asta, M Shahmanesh, Y G Vasiljev, F Potthoff, H S Randeva, G De Berardis, J O Logan, K Warncke, P Uitterlinden, E Rehring, K Gilmore, K Shankhdhar, V V Bojko, M Vahatalo, E A Korolyova, D Wiemann, P G Lankisch, D Hendrie, F Galtier, M Rybarczyk, Gisela Dahlquist, N N Rudovich, G Stein, A Liebl, F Tan, A Westerlund, S Gronemann, I Franklin, Jonathan A. Prince, Peter Arner, E Skliros, T. Sparre, M Vigas, Maddalena Trombetta, L. Bjerre Knudsen, A C Sima, I Dubroca, Alastair Gray, I Weets, R Ferraresi, Schauer Ujw., E. Leinonen, S Corazza, Jonathan Levy, P K Prakash, R Guzder, S. Barnhill, John Blangero, J Herreros, G. de Vries, Cheng Ptw., A Macías-Batista, K. 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Jensen, G, Fisher, A, Petrovsky, N, Srikusalanukul, W, Budge, M, Trifunovic zamaklar, D, Zivkovic, M, Jelic, V, Vukomanovic, G, Ristic, A, Seferovic, P, Costa, J, Duarte, S, Manley, S, Sailesh, S, Venkataraman, A, Haider, Y, Groza, I, Oprean, M, Ardelean, A, Morosanu, A, Darkow, T, Vanderplas, A, Mamas, M, Mcelduff, P, Burns, J, Edwards, R, Fitchet, A, Young, R, Gibson, J, Lichiardopol, R, Niculescu, N, Totora, A, Pencea, C, Tomescu, I, Cinteza, M, Manicardi, V, Coscelli, C, Navazio, A, Catellani, E, Michelini, M, Dall'Asta, D, Guberti, A, Piazza, A, Gasparini, E, Pantaleoni, M, Guiducci, U, Manari, A, Sejil, S, Janand delenne, B, Avierinos, J, Habib, G, Labastie, N, Vague, P, Lassmann vague, V, Luźniak, P, Tatoń, J, Wojciechowska Luźniak, A, Zairis, M, Lyras, A, Patsourakos, N, Tsirimbis, V, Foussas, S, Lupón, J, Urrutia, A, Herreros, J, González, B, Coll, R, Altimir, S, Prats, M, Valle, V, Abreu padí, C, Rábago, G, Ivanova, L, Brasacchio, D, Harno, E, Keenan, A, Li, H, Lu, Z, Ke, L, Liu, H, Jeong, I, Chae, M, Choi, M, Yoo, H, Kim, C, Yun, M, Na, M, Kang, Y, Kong, O, Son, S, Kim, I, Tanaka, N, Hosoi, M, Matsuyama, Y, Fukumoto, M, Yamakita, T, Yoshioka, K, Ishii, T, Sato, T, Fujii, S, Aoki, T, Shibata, T, Mizutani, N, Suzuki, J, Fowelin, J, Samuelsson, P, Brandrup wogsen, G, Okumura, K, Tokmakova, A, Staroverova, D, Antcieferov, M, Shutichina, I, Kuntchevich, G, Vriesendorp, T, Morélis, Q, Legemate, D, Schaper, F, Mainas, E, Gkioulmpasanis, I, Panagiotou, I, Vassilikos, G, Skorda, L, Sidira, M, Christoforidou, M, Alaveras, A, Artikis, V, Evdemon, E, Lechleitner, M, Koch, T, Ebenbichler, C, Sturm, W, Moretti, L, Moruzzo, D, Boldrini, E, Pandolfo, C, Kameyama, M, Iwasa, R, Cho, M, Nam, J, Huh, K, Kaplar, M, Paragh, G, Erdei, A, Csongradi, E, Garai, I, Varga, J, Galuska, L, Udvardy, M, Higa, M, Kaneko, Y, Hiroi, N, Koziarska, D, Nowacki, P, Majkowska, L, Luzniak, P, Wojciechowska luźniak, A, Tushuizen, M, Nieuwland, R, Snoeck, D, Sturk, A, Diamant, M, Aguiar, L, Bahia, L, Villela, N, Laflor, C, Conde, C, Bottino, D, Dorigo, D, Bouskela, E, Pu, S, Luo, Z, Lam, K, Dan, Q, Xu, A, Shen, J, Cheng, K, Xu, J, Thamer, C, Stefan, N, Haap, M, Heller, E, Tschritter, O, De Prado, A, Ortiz, A, Ybarra, J, Gich, I, Pou, J, Ehren, M, Roggenland, D, Reinsen, B, Klein, H, Rittig, K, Stock, J, Kocher, B, Balletshofer, B, Shon, H, Chung, D, Nakatani, Y, Matsuhisa, M, Kaneto, H, Hatazaki, M, Yoshiuchi, K, Katakami, N, Kawamori, D, Ohtoshi, K, Sakamoto, K, Matsuoka, T, Ozawa, K, Ogawa, S, Hori, M, Yamasaki, Y, Zitouni, K, Harry, D, Nourooz zadeh, J, Earle, K, Olesen, P, Franco, L, Corvaja, C, Semplicini, A, Ceylan işık, A, Arı, N, Rösen, P, Lee, I, Park, K, Jung, E, Shin, D, Jo, S, Obuobie, K, Prakash, P, Hanna, F, Lazarus, J, Varadhan, L, Gurushankar, J, James, D, Sheikh, S, Gaede, P, Zou, D, Vilarrasa, N, Perez maraver, M, Mena, E, Perez, D, Setti, G, Buckingham, R, Urbančič, V, Stefanovska, A, Bernjak, A, Ažman juvan, K, Kocijančič, A, Glowania, A, Filters, T, Fosmark, D, Torjesen, P, Kilhovd, B, Berg, T, Sandvik, L, Hanssen, K, Mentink, C, Donchenko, G, Stepanenko, S, Maingrette, F, Deng, H, Lindenmair, A, Freudenthaler, A, Baumgartner parzer, S, Nizheradze, K, Khoruzhenko, A, Tronko, N, Sheu, W, Ou, H, Shen, H, Lin, T, Wu, H, Yang, C, Mogylnytska, L, Schmoelzer, I, Davies, J, Band, M, Struthers, A, Prázný, M, Škrha, J, Kasalová, Z, Neelotpol, S, Jahan, P, Kauschke, S, Harrop, C, Schäfer, A, Widder, J, Eigenthaler, M, Walter, U, Uchimura, I, Ikebukuro, M, Kaibara, M, Hirata, M, Helal, R, Pervin, F, Yang, X, Jansson, P, Nagaev, I, Jack, M, Carvalho, E, Sunnerhagen, K, Cam, M, Cushman, S, Smith, U, Creely, S, Farmer, J, Gustafson, B, Kusminski, C, Krusinova, E, Wohl, P, Klementova, M, Lanska, V, Mcdougall, C, Kelly, I, Abbas, Z, Lutale, J, Archibald, L, Karunajeewa, H, Stingemore, N, Stuccio, G, Mcgechie, D, Muller, L, Hak, E, Goudzwaard, W, Montorsi, F, Homering, M, Sprenger, K, Goldstein, I, Asnaghi, V, Ferrari, G, Rastaldi, M, Gabellini, D, Dell'Antonio, G, Maestroni, A, Ruggieri, D, Luzi, L, Piemonti, L, Zerbini, G, Anafaroglu, I, Tutuncu, N, Sultana, M, Siddiqua, N, Iwasaki, T, Nakajima, A, Yoneda, M, Mukasa, K, Tanaka, S, and Sekihara, H
Subjects: 0303 health sciences, medicine.medical_specialty, business.industry, EASD, Endocrinology, Diabetes and Metabolism, Human physiology, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Diabetes mellitus, Family medicine, Internal Medicine, Medicine, business, 030217 neurology & neurosurgery, 030304 developmental biology
Published: 2004

24. Erratum to: Low plasma adiponectin levels predict increased urinary albumin/creatinine ratio in type 2 diabetes patients

Author: I. Kacso, A. Lenghel, C. I. Bondor, D. Moldovan, C. Rusu, C. Nita, N. Hancu, M. Gherman Caprioara, and G. Kacso
Subjects: Nephrology, Urology
Published: 2012
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25. Fabry disease: classic phenotype in alarge family affected by a novel mutation (A292T) in the α-galactosidase a gene

Author: C. Craciun, V. Tibre, R.H. Lekanne Deprez, Ina Maria Kacso, S. Pops, V. Todea, C. Spanu, C. Nita, Ben J. H. M. Poorthuis, and C. Drugan
Subjects: Pharmacology, α galactosidase a, business.industry, Medicine, Pharmacology (medical), business, medicine.disease, Fabry disease, Phenotype, Gene, Novel mutation, Molecular biology
Published: 2007
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26. V-03.03

Author: Petrisor Geavlete, V. Mirciulescu, C. Nita, and S. Aghamiri
Subjects: medicine.medical_specialty, business.industry, Urology, medicine, Ureteral stenosis, business, Laser vaporization
Published: 2006
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27. Tu-W17:6 The hypertensive waist - first step of the screening of the metabolic syndrome

Author: N. Hancu, L. Szentagotai, G. Roman, and C. Nita
Subjects: medicine.medical_specialty, Waist, Endocrinology, business.industry, Internal medicine, Internal Medicine, medicine, General Medicine, Metabolic syndrome, Cardiology and Cardiovascular Medicine, medicine.disease, business
Published: 2006
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28. Stratospheric eruptions from tropical and extra-tropical volcanoes constrained using high-resolution sulfur isotopes in ice cores

Author: Joseph R. McConnell, Michael Sigl, Jess F. Adkins, Andrea Burke, Kathryn A. Moore, D. C. Nita, European Commission, University of St Andrews. School of Earth & Environmental Sciences, and University of St Andrews. St Andrews Isotope Geochemistry
Subjects: Katmai, 010504 meteorology & atmospheric sciences, Mass-independent fractionation, Volcanism, 010502 geochemistry & geophysics, Atmospheric sciences, 01 natural sciences, Atmosphere, chemistry.chemical_compound, Ice core, Geochemistry and Petrology, Earth and Planetary Sciences (miscellaneous), SDG 13 - Climate Action, Sulfate, Stratosphere, 0105 earth and related environmental sciences, geography, geography.geographical_feature_category, GE, DAS, Radiative forcing, Geophysics, Volcano, chemistry, 13. Climate action, Space and Planetary Science, Ice cores, Volcanoes, Geology, Sulfur, GE Environmental Sciences
Abstract: This research was funded by a Foster and Coco Stanback postdoctoral fellowship and a Marie Curie Career Integration Grant (CIG14-631752) to AB and a NSF-OCE grant 1340174 and NSF-EAR grant 1349858 to JFA. MS acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement No 820047). NSF-PLR grant 1204176 to JRM supported collection and analysis of the Tunu2013 core. The record of volcanic forcing of climate over the past 2500 years is based primarily on sulfate concentrations in ice cores. Of particular interest are large volcanic eruptions with plumes that reached high altitudes in the stratosphere, as these afford sulfate aerosols the longest residence time in the atmosphere, and thus have the greatest impact on radiative forcing. Sulfur isotopes measured in ice cores can be used to identify these large eruptions because stratospheric sulfur is exposed to UV radiation, which imparts a time-evolving mass independent fractionation (MIF) that is preserved in the ice. However, sample size requirements of traditional measurement techniques mean that the MIF signal may be obscured, leading to an inconclusive result. Here we present a new method of measuring sulfur isotopes in ice cores by multi-collector inductively coupled plasma mass spectrometry, which reduces sample size requirements by three orders of magnitude. Our method allows us to measure samples containing as little as 10 nmol of sulfur, with a precision of 0.11‰ for δ34S and 0.10‰ for Δ33S, enabling a high-temporal resolution over ice core sulfate peaks. We tested this method on known tropical (Tambora 1815 and Samalas 1257) and extra-tropical (Katmai/Novarupta 1912) stratospheric eruptions from the Tunu2013 ice core in Greenland and the B40 ice core from Antarctica. These high-resolution sulfur isotope records suggest a distinct difference between the signatures of tropical versus extra-tropical eruptions. Furthermore, isotope mass balance on sulfate from extra-tropical eruptions provides a means to estimate the fraction of sulfate deposited that was derived from the stratosphere. This technique applied to unidentified eruptions in ice cores may thus improve the record of explosive volcanism and its forcing of climate. Postprint
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29. [Basis of health care--public health nurses and lessons in the capabilities of local residents]

Author: C, Nita, R, Ogome, M, Fujimori, R, Fujino, and M, Zaibe
Subjects: Japan, Public Health Nursing, Community Participation, Humans
Published: 1988

30. Remarks on Amplitude — Pressure Characteristic Phenomenon

Author: L. Batorski, P. Wollk-Laniewski, Wojciech Zaworski, Marek Czosnyka, and C. Nita
Subjects: Physics, Space model, Cerebral blood volume, Amplitude, Cerebrospinal fluid, Cerebral blood flow, Pulsatile flow, Pulse wave, Mechanics, Intracranial pressure
Abstract: A pulse wave is the most characteristic component of the intracranial pressure (ICP) signal. Many authors have devoted their work to questions concerning its mechanisms and clinical validation, however, most of these questions remain still open. It should also be emphasized, that almost all the theoretical works dealing with the cerebrospinal space model except a few (Hoffmann 1985, Sorak 1986) do not discuss the phenomenon of pulsatile changes of cerebral blood volume (CBV). The model introduced by Marmarou (1976) describes only the cerebrospinal fluid (CSF) circulation and phenomena concerning the CSF container such as infusion or bolus tests, but cerebral blood flow (CBF) is not included in the model. Therefore, the amplitude-pressure (AMP-P) characteristic cannot be explained in the same way as a linear relationship between the cerebrospinal elastance and the pressure level.
Published: 1989
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31. Signatures for a nuclear quantum phase transition from E 0 and E 2 observables in Gd isotopes.

Author: J. Wiederhold, R. Kern, C. Lizarazo, N. Pietralla, V. Werner, R.V. Jolos, D. Bucurescu, N. Florea, D. Ghita, T. Glodariu, R. Lica, N. Marginean, R. Marginean, C. Mihai, R. Mihai, I.O. Mitu, A. Negret, C. Nita, A. Olacel, and S. Pascu
Published: 2018
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32. Thermal and fluid simulation of the environment under the dashboard, compared with measurement data.

Author: C S Popescu, G M Sirbu, and I C Nita
Published: 2017
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33. Study of 16O(12C,α20Ne)α for the investigation of carbon-carbon fusion reaction via the Trojan Horse Method.

Author: G.G. Rapisarda, C Spitaleri, C. Bordeanu, Z. Hons, G.G. Kiss, M. La Cognata, J. Mrazek, C. Nita, D. Pantelica, H. Petrascu, R.G. Pizzone, S. Romano, T. Szücs, L. Trache, A. Tumino, and G. Velisa
Published: 2016
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34. A pilot feasibility study comparing large language models in extracting key information from ICU patient text records from an Irish population.

Author: Urquhart E, Ryan J, Hartigan S, Nita C, Hanley C, Moran P, Bates J, Jooste R, Judge C, Laffey JG, Madden MG, and McNicholas BA
Abstract: Background: Artificial intelligence, through improved data management and automated summarisation, has the potential to enhance intensive care unit (ICU) care. Large language models (LLMs) can interrogate and summarise large volumes of medical notes to create succinct discharge summaries. In this study, we aim to investigate the potential of LLMs to accurately and concisely synthesise ICU discharge summaries., Methods: Anonymised clinical notes from ICU admissions were used to train and validate a prompting structure in three separate LLMs (ChatGPT, GPT-4 API and Llama 2) to generate concise clinical summaries. Summaries were adjudicated by staff intensivists on ability to identify and appropriately order a pre-defined list of important clinical events as well as readability, organisation, succinctness, and overall rank., Results: In the development phase, text from five ICU episodes was used to develop a series of prompts to best capture clinical summaries. In the testing phase, a summary produced by each LLM from an additional six ICU episodes was utilised for evaluation. Overall ability to identify a pre-defined list of important clinical events in the summary was 41.5 ± 15.2% for GPT-4 API, 19.2 ± 20.9% for ChatGPT and 16.5 ± 14.1% for Llama2 (p = 0.002). GPT-4 API followed by ChatGPT had the highest score to appropriately order a pre-defined list of important clinical events in the summary as well as readability, organisation, succinctness, and overall rank, whilst Llama2 scored lowest for all. GPT-4 API produced minor hallucinations, which were not present in the other models., Conclusion: Differences exist in large language model performance in readability, organisation, succinctness, and sequencing of clinical events compared to others. All encountered issues with narrative coherence and omitted key clinical data and only moderately captured all clinically meaningful data in the correct order. However, these technologies suggest future potential for creating succinct discharge summaries., (© 2024. The Author(s).)
Published: 2024
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35. Evaluation of reduced ('Lite') compression versus brief bandaging to manage post-operative pain after total knee arthroplasty surgery; a single-centre randomised controlled trial.

Author: Dawson M, Hage W, Nita C, Bell L, Gorman J, and Jonker L
Subjects: Humans, Male, Female, Aged, Middle Aged, Prospective Studies, Pain Management methods, Treatment Outcome, Aged, 80 and over, Arthroplasty, Replacement, Knee adverse effects, Pain, Postoperative prevention & control, Compression Bandages, Pain Measurement
Abstract: Purpose: Investigate efficacy of reduced compression bandage for the control of pain after total knee arthroplasty., Patients & Methods: Prospective, single-centre, randomised controlled trial involving data for 56 out of 94 consented patients; 29 standard care versus 27 Andoflex TLC Calamine Lite. Comparison of standard care (non-compression bandage applied for up to one day) versus Andoflex TLC Calamine Lite (25-30 mmHg) two-layer compression bandage worn for five days. Outcomes measured with validated pain (McGill, 10-cm visual scale) and functionality (KOOS) tools., Results: At day 5 post-surgery, the median pain level was 3.0 cm vs 4.0 cm (p-value 0.47, Mann-Whitney U test) respectively. Generic pain levels, pain types, and knee functionality did not differ between the interventions at days 3/5/12 and week 6 post-surgery. An exception was the degree of 'tender' pain at day 12, which was significantly lower in the Andoflex TLC Calamine Lite arm (p-value 0.041, Mann-Whitney U test). Binary logistic regression analysis showed that application of Andoflex TLC Calamine Lite, administration of oxycodone, and male sex were all significantly associated with less 'tender' pain., Conclusion: Reduced compression bandaging does not affect overall pain levels post knee arthroplasty surgery, but may alleviate pain experienced as 'tender', highlighting the different types of pain that may be experienced. Patients' need for, and the use of, opioid medication (oxycodone) is a significant confounding variable when assessing adjuvant therapy to control pain. The applicability of reduced compression bandaging may therefore be limited and is less efficient than medical pain control., Competing Interests: Declaration of competing interest Leon Jonker has in past received a single honorarium for non-orthopaedic consultancy work for Milliken Healthcare. The other authors have no conflict of interest to declare., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Published: 2024
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36. Calcinosis in Rheumatic Disease Is Still an Unmet Need: A Retrospective Single-Center Study.

Author: Nita C, Groseanu L, Opris D, Predeteanu D, Bojinca V, Berghea F, Vlad V, Abobului M, Constantinescu C, Negru M, Saulescu I, Daia S, Mazilu D, Borangiu A, Cobilinschi C, Mardale D, Rosu M, and Balanescu A
Abstract: Patients with immune-mediated rheumatic disease-related calcinosis comprise a subgroup at risk of encountering a more severe clinical outcome. Early assessment is pivotal for preventing overall disease progression, as calcinosis is commonly overlooked until several years into the disease and is considered as a 'non-lethal' manifestation. This single-center retrospective study explored the prevalence, clinical associations, and impact on survival of subcutaneous calcinosis in 86 patients with immune-mediated rheumatic diseases (IMRD). Calcinosis predominantly appeared in individuals with longstanding disease, particularly systemic sclerosis (SSc), constituting 74% of cases. Smaller calcinosis lesions (≤1 cm) were associated with interstitial lung disease, musculoskeletal involvement, and digital ulcerations, while larger lesions (≥4 cm) were associated with malignancy, severe peripheral artery disease, and systemic arterial hypertension. The SSc calcinosis subgroup exhibited a higher mean adjusted European Scleroderma Study Group Activity Index score than those without. However, survival rates did not significantly differ between the two groups. Diltiazem was the most commonly used treatment, and while bisphosphonates reduced complications related to calcinosis, complete resolution was not achieved. The findings underscore current limitations in diagnosing, monitoring, and treating calcinosis, emphasizing the need for further research and improved therapeutic strategies to improve patient care and outcomes.
Published: 2024
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37. Achieving the hip fracture Best Practise Tariff during the COVID-19 pandemic.

Author: Ali M, Fadulelmola A, Urwin M, and Nita C
Abstract: Objectives: Achieving the hip fracture best practice tariff is associated with decreased mortality rates. The aim of this study is to evaluate the impact of Covid-19 pandemic on achieving Best Practice Tariff., Methods: We retrospectively reviewed all adult hip fractures admitted to our unit between March and June 2020. Patient's characteristics, place of residence, delirium assessment, and mobility status were recorded. All the Best practice Tariff criteria have been analysed. Covid-19 was diagnosed using reverse transcriptase polymerase chain reaction., Results: 178 patients with a mean age of 82.8 years presented with hip fractures during the study period. 18 patients (10.1%) tested positive for COVID-19. 44.4% failed to achieve the BPT from the COVID-19 positive group and 22.5% from the negative group., Conclusion: Based on this study, hip fractures associated with Covid-19 infection are more likely to fail the BPT and have higher 30-day mortality rates compare to the COVID-19 negative patients., (Copyright: © 2022 Hylonome Publications.)
Published: 2022
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38. Comparison of antibody response to two different mRNA Covid-19 vaccines in patients on hemodialysis.

Author: Ionita C, Marcelli D, Nita C, Anton C, Berca S, Vacar S, Schiller O, Gheorghiu C, and Barth C
Subjects: 2019-nCoV Vaccine mRNA-1273, Antibody Formation, BNT162 Vaccine, Humans, RNA, Messenger genetics, Renal Dialysis, SARS-CoV-2, COVID-19, COVID-19 Vaccines
Abstract: Introduction: In hemodialysis patients, coronavirus disease 2019 is associated with high morbidity and mortality. Aim of the study was to evaluate the antibody level against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients treated with two different mRNA-based vaccines, in a multicenter survey., Patients and Methods: Since April 2020, in the 5 participating Centers, periodic screening of all patients with PCR testing has been performed every 2 weeks. The study included two cohorts of patients on maintenance hemodialysis treated with the BNT162b2 or with the mRNA-1273 Covid-19 vaccine. The tests for antibodies against the receptor-binding domain was performed by the anti-SARS-CoV-2 S enzyme immunoassay (Roche Elecsys)., Results: Of the 398 included patients, 303 received the BNT162b2 and 95 the mRNA-1273 vaccine. In patients without previous infection, the median levels of anti-S antibodies were 297 U/mL and 1,032 U/mL for those treated with BNT162b2 or mRNA-1273, respectively (p < 0.001). In patients with previous infection, the median levels of SARS-CoV-2 anti-S antibodies were 7,516 U/mL and 17,495 U/mL for those treated with BNT162b2 or mRNA-1273, respectively (p = 0.005). The Charlson comorbidity index (CCI) was significantly associated with protective levels of anti-spike IgG, with 3.6% of low- or non-responders having a CCI of 2-4 versus 18.9% in those with a CCI of 8 or more. The adjusted OR of developing a sufficient antibody level between the two vaccines was 3.91 (p = 0.0766) in favor of mRNA-1273., Conclusions: Both of the evaluated mRNA-based vaccines for SARS-CoV-2 showed good efficacy. Preliminary data may data suggest a higher antibody response to the mRNA-1273 vaccine., (© 2021. The Author(s) under exclusive licence to Italian Society of Nephrology.)
Published: 2022
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39. VisConnect: Distributed Event Synchronization for Collaborative Visualization.

Author: Schwab M, Saffo D, Zhang Y, Sinha S, Nita-Rotaru C, Tompkin J, Dunne C, and Borkin MA
Abstract: Tools and interfaces are increasingly expected to be synchronous and distributed to accommodate remote collaboration. Yet, adoption of these techniques for data visualization is low partly because development is difficult: existing collaboration software systems either do not support simultaneous interaction or require expensive redevelopment of existing visualizations. We contribute VisConnect: a web-based synchronous distributed collaborative visualization system that supports most web-based SVG data visualizations, balances system safety with responsiveness, and supports simultaneous interaction from many collaborators. VisConnect works with existing visualization implementations with little-to-no code changes by synchronizing low-level JavaScript events across clients such that visualization updates proceed transparently across clients. This is accomplished via a peer-to-peer system that establishes consensus among clients on the per-element sequence of events, and uses a lock service to grant access over elements to clients. We contribute collaborative extensions of traditional visualization interaction techniques, such as drag, brush, and lasso, and discuss different strategies for collaborative visualization interactions. To demonstrate the utility of VisConnect, we present novel examples of collaborative visualizations in the healthcare domain, remote collaboration with annotation, and show in an education case study for e-learning with 22 participants that students found the ability to remotely collaborate on class activities helpful and enjoyable for understanding concepts. A free copy of this paper and source code are available on OSF at osf.io/ut7e6 and at visconnect.us.
Published: 2021
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40. Link between Alkali Metals in Salt Templates and in Electrolytes for Improved Carbon-Based Electrochemical Capacitors.

Author: Platek-Mielczarek A, Nita C, Matei Ghimbeu C, Frackowiak E, and Fic K
Abstract: Various alkali metal (Li + , Na + , K + , Rb + , and Cs + ) chlorides with Pluronic F127 were used as a soft-salt template for tuning the textural and structural properties of carbon. Highly conductive metal hydroxide solutions, where the cations are the same as those in the salt template, have been used as electrolytes. By increasing the size of the cation in the template, the textural properties of carbon, such as the specific surface area, micropore volume, and pore size, were remarkably enhanced. It directly translates to an increase in the specific capacitance of the electrode material. For a constant current charge/discharge at 0.1 A g -1 , the electrode composed of LiCl-T and operating with 1 mol L -1 LiOH demonstrates the capacitance of 124 F g -1 , whereas CsCl-T with the same electrolyte has a capacitance of 216 F g -1 . Moreover, the materials show the highest capacitance retention (up to 75%) vs. the current regime applied when the cation used during synthesis matches the cation present in the electrolyte (i.e., LiCl-T with LiOH). Interestingly, capacitance normalized by specific surface area has been found to be the highest when LiOH solution is applied as an electrolyte. Thus, for this metric, the size of ions seems to be a crucial parameter. The importance of mesoporosity is highlighted as well by using materials with a similar fraction of micropores and with or without mesopores. Briefly, the presence of mesopore fraction proved to be essential for improved capacity retention (69% vs. 30%). Besides textural properties, the graphitization degree impacts the electrochemical performance as well. It increases among the samples, in accordance with cation-π binding energy, e.g., LiCl-T is the most "graphitic-like" material and CsCl-T is the most disordered. Thus, the more graphitic-like materials demonstrate higher rate capability and cycle stability.
Published: 2021
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41. Competition between Allowed and First-Forbidden β Decay: The Case of ^{208}Hg→^{208}Tl.

Author: Carroll RJ, Podolyák Z, Berry T, Grawe H, Alexander T, Andreyev AN, Ansari S, Borge MJG, Brunet M, Creswell JR, Fraile LM, Fahlander C, Fynbo HOU, Gamba ER, Gelletly W, Gerst RB, Górska M, Gredley A, Greenlees PT, Harkness-Brennan LJ, Huyse M, Judge SM, Judson DS, Konki J, Kurcewicz J, Kuti I, Lalkovski S, Lazarus IH, Lică R, Lund M, Madurga M, Marginean N, Marginean R, Marroquin I, Mihai C, Mihai RE, Nácher E, Negret A, Nita C, Pascu S, Page RD, Patel Z, Perea A, Phrompao J, Piersa M, Pucknell V, Rahkila P, Rapisarda E, Regan PH, Rotaru F, Rudigier M, Shand CM, Shearman R, Stegemann S, Stora T, Sotty C, Tengblad O, Van Duppen P, Vedia V, Wadsworth R, Walker PM, Warr N, Wearing F, and De Witte H
Abstract: The β decay of ^{208}Hg into the one-proton hole, one neutron-particle _{81}^{208}Tl_{127} nucleus was investigated at CERN-ISOLDE. Shell-model calculations describe well the level scheme deduced, validating the proton-neutron interactions used, with implications for the whole of the N>126, Z<82 quadrant of neutron-rich nuclei. While both negative and positive parity states with spin 0 and 1 are expected within the Q_{β} window, only three negative parity states are populated directly in the β decay. The data provide a unique test of the competition between allowed Gamow-Teller and Fermi, and first-forbidden β decays, essential for the understanding of the nucleosynthesis of heavy nuclei in the rapid neutron capture process. Furthermore, the observation of the parity changing 0^{+}→0^{-}β decay where the daughter state is core excited is unique, and can provide information on mesonic corrections of effective operators.
Published: 2020
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42. Sequential Nature of (p,3p) Two-Proton Knockout from Neutron-Rich Nuclei.

Author: Frotscher A, Gómez-Ramos M, Obertelli A, Doornenbal P, Authelet G, Baba H, Calvet D, Château F, Chen S, Corsi A, Delbart A, Gheller JM, Giganon A, Gillibert A, Isobe T, Lapoux V, Matsushita M, Momiyama S, Motobayashi T, Niikura M, Otsu H, Paul N, Péron C, Peyaud A, Pollacco EC, Roussé JY, Sakurai H, Santamaria C, Sasano M, Shiga Y, Shimizu N, Steppenbeck D, Takeuchi S, Taniuchi R, Uesaka T, Wang H, Yoneda K, Ando T, Arici T, Blazhev A, Browne F, Bruce AM, Carroll R, Chung LX, Cortés ML, Dewald M, Ding B, Dombradi Z, Flavigny F, Franchoo S, Giacoppo F, Górska M, Gottardo A, Hadyńska-Klęk K, Korkulu Z, Koyama S, Kubota Y, Jungclaus A, Lee J, Lettmann M, Linh BD, Liu J, Liu Z, Lizarazo C, Louchart C, Lozeva R, Matsui K, Miyazaki T, Moschner K, Nagamine S, Nakatsuka N, Nita C, Nishimura S, Nobs CR, Olivier L, Ota S, Patel Z, Podolyák Z, Rudigier M, Sahin E, Saito TY, Shand C, Söderström PA, Stefan IG, Sumikama T, Suzuki D, Orlandi R, Vaquero V, Vajta Z, Werner V, Wimmer K, Wu J, and Xu Z
Abstract: Twenty-one two-proton knockout (p,3p) cross sections were measured from neutron-rich nuclei at ∼250 MeV/nucleon in inverse kinematics. The angular distribution of the three emitted protons was determined for the first time, demonstrating that the (p,3p) kinematics are consistent with two sequential proton-proton collisions within the projectile nucleus. Ratios of (p,3p) over (p,2p) inclusive cross sections follow the trend of other many-nucleon removal reactions, further reinforcing the sequential nature of (p,3p) in neutron-rich nuclei.
Published: 2020
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43. Prominence of Pairing in Inclusive (p,2p) and (p,pn) Cross Sections from Neutron-Rich Nuclei.

Author: Paul N, Obertelli A, Bertulani CA, Corsi A, Doornenbal P, Rodriguez-Sanchez JL, Authelet G, Baba H, Calvet D, Château F, Chen S, Delbart A, Gheller JM, Giganon A, Gillibert A, Isobe T, Lapoux V, Matsushita M, Momiyama S, Motobayashi T, Niikura M, Otsu H, Péron C, Peyaud A, Pollacco EC, Roussé JY, Sakurai H, Santamaria C, Sasano M, Shiga Y, Steppenbeck D, Takeuchi S, Taniuchi R, Uesaka T, Wang H, Yoneda K, Ando T, Arici T, Blazhev A, Browne F, Bruce AM, Carroll R, Chung LX, Cortés ML, Dewald M, Ding B, Dombradi Z, Flavigny F, Franchoo S, Giacoppo F, Górska M, Gottardo A, Hadynska-Klek K, Korkulu Z, Koyama S, Kubota Y, Jungclaus A, Lee J, Lettmann M, Linh BD, Liu J, Liu Z, Lizarazo C, Louchart C, Lozeva R, Matsui K, Miyazaki T, Moschner K, Nagamine S, Nakatsuka N, Nita C, Nishimura S, Nobs CR, Olivier L, Ota S, Patel Z, Podolyák Z, Rudigier M, Sahin E, Saito TY, Shand C, Söderström PA, Stefan IG, Sumikama T, Suzuki D, Orlandi R, Vaquero V, Vajta Z, Werner V, Wimmer K, Wu J, and Xu Z
Abstract: Fifty-five inclusive single nucleon-removal cross sections from medium mass neutron-rich nuclei impinging on a hydrogen target at ∼250 MeV/nucleon are measured at the RIKEN Radioactive Isotope Beam Factory. Systematically higher cross sections are found for proton removal from nuclei with an even number of protons as compared to odd-proton number projectiles for a given neutron separation energy. Neutron removal cross sections display no even-odd splitting, contrary to nuclear cascade model predictions. Both effects are understood through simple considerations of neutron separation energies and bound state level densities originating in pairing correlations in the daughter nuclei. These conclusions are supported by comparison with semimicroscopic model predictions, highlighting the enhanced role of low-lying level densities in nucleon-removal cross sections from loosely bound nuclei.
Published: 2019
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44. Hypertensive Waist and Lipid Accumulation Product as Predictors of Metabolic Syndrome.

Author: Nita C, Rusu A, Hancu N, Roman G, and Bala C
Subjects: Body Mass Index, Humans, Waist Circumference, Hypertension, Lipid Accumulation Product, Metabolic Syndrome
Published: 2018
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45. Shape Evolution in Neutron-Rich Krypton Isotopes Beyond N=60: First Spectroscopy of ^{98,100}Kr.

Author: Flavigny F, Doornenbal P, Obertelli A, Delaroche JP, Girod M, Libert J, Rodriguez TR, Authelet G, Baba H, Calvet D, Château F, Chen S, Corsi A, Delbart A, Gheller JM, Giganon A, Gillibert A, Lapoux V, Motobayashi T, Niikura M, Paul N, Roussé JY, Sakurai H, Santamaria C, Steppenbeck D, Taniuchi R, Uesaka T, Ando T, Arici T, Blazhev A, Browne F, Bruce A, Carroll R, Chung LX, Cortés ML, Dewald M, Ding B, Franchoo S, Górska M, Gottardo A, Jungclaus A, Lee J, Lettmann M, Linh BD, Liu J, Liu Z, Lizarazo C, Momiyama S, Moschner K, Nagamine S, Nakatsuka N, Nita C, Nobs CR, Olivier L, Orlandi R, Patel Z, Podolyák Z, Rudigier M, Saito T, Shand C, Söderström PA, Stefan I, Vaquero V, Werner V, Wimmer K, and Xu Z
Abstract: We report on the first γ-ray spectroscopy of low-lying states in neutron-rich ^{98,100}Kr isotopes obtained from ^{99,101}Rb(p,2p) reactions at ∼220 MeV/nucleon. A reduction of the 2_{1}^{+} state energies beyond N=60 demonstrates a significant increase of deformation, shifted in neutron number compared to the sharper transition observed in strontium and zirconium isotopes. State-of-the-art beyond-mean-field calculations using the Gogny D1S interaction predict level energies in good agreement with experimental results. The identification of a low-lying (0_{2}^{+}, 2_{2}^{+}) state in ^{98}Kr provides the first experimental evidence of a competing configuration at low energy in neutron-rich krypton isotopes consistent with the oblate-prolate shape coexistence picture suggested by theory.
Published: 2017
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46. Are There Signatures of Harmonic Oscillator Shells Far from Stability? First Spectroscopy of ^{110}Zr.

Author: Paul N, Corsi A, Obertelli A, Doornenbal P, Authelet G, Baba H, Bally B, Bender M, Calvet D, Château F, Chen S, Delaroche JP, Delbart A, Gheller JM, Giganon A, Gillibert A, Girod M, Heenen PH, Lapoux V, Libert J, Motobayashi T, Niikura M, Otsuka T, Rodríguez TR, Roussé JY, Sakurai H, Santamaria C, Shimizu N, Steppenbeck D, Taniuchi R, Togashi T, Tsunoda Y, Uesaka T, Ando T, Arici T, Blazhev A, Browne F, Bruce AM, Carroll R, Chung LX, Cortés ML, Dewald M, Ding B, Flavigny F, Franchoo S, Górska M, Gottardo A, Jungclaus A, Lee J, Lettmann M, Linh BD, Liu J, Liu Z, Lizarazo C, Momiyama S, Moschner K, Nagamine S, Nakatsuka N, Nita C, Nobs CR, Olivier L, Patel Z, Podolyák Z, Rudigier M, Saito T, Shand C, Söderström PA, Stefan I, Orlandi R, Vaquero V, Werner V, Wimmer K, and Xu Z
Abstract: The first measurement of the low-lying states of the neutron-rich ^{110}Zr and ^{112}Mo was performed via in-beam γ-ray spectroscopy after one proton removal on hydrogen at ∼200 MeV/nucleon. The 2_{1}^{+} excitation energies were found at 185(11) keV in ^{110}Zr, and 235(7) keV in ^{112}Mo, while the R_{42}=E(4_{1}^{+})/E(2_{1}^{+}) ratios are 3.1(2), close to the rigid rotor value, and 2.7(1), respectively. These results are compared to modern energy density functional based configuration mixing models using Gogny and Skyrme effective interactions. We conclude that first levels of ^{110}Zr exhibit a rotational behavior, in agreement with previous observations of lighter zirconium isotopes as well as with the most advanced Monte Carlo shell model predictions. The data, therefore, do not support a harmonic oscillator shell stabilization scenario at Z=40 and N=70. The present data also invalidate predictions for a tetrahedral ground state symmetry in ^{110}Zr.
Published: 2017
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47. Adiponectin predicts cardiovascular events in diabetes dialysis patients.

Author: Kacso IM, Potra AR, Bondor CI, Moldovan D, Rusu C, Patiu IM, Racasan S, Orasan R, Vladutiu D, Spanu C, Rusu A, Nita C, Moldovan R, Ghigolea B, and Kacso G
Subjects: Atherosclerosis blood, Cardiovascular Diseases blood, Cohort Studies, Female, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Multivariate Analysis, Proportional Hazards Models, Regression Analysis, Treatment Outcome, Adiponectin blood, Cardiovascular Diseases diagnosis, Diabetes Mellitus blood, Renal Dialysis
Abstract: Objectives: Adiponectin is an insulin-sensitizing, anti-inflammatory adipokine with anti-atherogenic actions in the general population. In dialysis patients it is unclear whether adiponectin conserves its protective value or is, on the contrary, associated to worse prognosis. We assessed the predictive value of adiponectin for atherosclerosis related cardiovascular events in type 2 diabetic dialysis patients., Design and Methods: Prevalent diabetic dialysis patients from three dialysis units (n=77) were enrolled in a 3years' prospective observational study. Serum adiponectin, clinical and laboratory parameters were determined at baseline; new occurrence of atherosclerosis related events (coronary events, atherosclerosis obliterans, and stroke) was recorded., Results: Baseline adiponectin was 17.25(9.53-31.97) μg/mL and significantly correlated to HDL cholesterol (r=0.29, p=0.01), triglycerides (r=-0.40, p=0.0004), ferritin (r=-0.29, p=0.02), transferrin (r=-0.28, p=0.02), and uric acid (r=-0.24, p=0.04). In multivariate analysis association to triglycerides (p=0.001), HDL cholesterol (p=0.01) and ferritin (p=0.04) remained significant. 36 new fatal and non-fatal new cardiovascular events occurred, 29 patient died. Cox proportional regression analysis showed that adiponectin below or above a ROC-derived cut-off of 27.33μg/mL significantly influenced event-free survival: hazard ratio (HR) 2.48, 95% confidence interval (CI) (1.09-5.66), p=0.031 along with fasting glucose HR 1.01, 95%CI(1.00-1.02), p=0.01 and history of cardiovascular events at inclusion HR 3.16, 95%CI(1.36-7.32), p=0.007. In multivariate analysis baseline adiponectin HR 5.02, 95%CI(0.98-25.06), p=0.05 and glycemia HR 1.01, 95%CI(1.00-1.02), p=0.01 influenced event-free survival. Adiponectin also predicted cardiovascular events in patients without cardiovascular disease at inclusion but was not associated to overall mortality., Conclusions: In diabetes dialysis patients low adiponectin favors occurrence of atherosclerosis related cardiovascular events., (Copyright © 2015 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.)
Published: 2015
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48. GPU-accelerated model for fast, three-dimensional fluid-structure interaction computations.

Author: Nita C, Itu L, Mihalef V, Sharma P, and Rapaka S
Subjects: Computer Simulation
Abstract: In this paper we introduce a methodology for performing one-way Fluid-Structure interaction (FSI), i.e. where the motion of the wall boundaries is imposed. We use a Graphics Processing Unit (GPU) accelerated Lattice-Boltzmann Method (LBM) implementation and present an efficient workflow for embedding the moving geometry, given as a set of polygonal meshes, in the LBM computation. The proposed method is first validated in a synthetic experiment: a vessel which is periodically expanding and contracting. Next, the evaluation focuses on the 3D Peristaltic flow problem: a fluid flows inside a flexible tube, where a periodic wave-like deformation produces a fluid motion along the centerline of the tube. Different geometry configurations are used and results are compared against previously published solutions. The efficient approach leads to an average execution time of approx. one hour per computation, whereas 50% of it is required for the geometry update operations. Finally, we also analyse the effect of changing the Reynolds number on the flow streamlines: the flow regime is significantly affected by the Reynolds number.
Published: 2015
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49. ESAM predicts cardiovascular mortality in diabetic hemodialysis patients.

Author: Kacso IM, Potra AR, Bondor CI, Moldovan D, Rusu C, Patiu IM, Racasan S, Orasan R, Moldovan R, Ghigolea B, Vladutiu D, Spanu C, Nita C, and Rusu A
Abstract: Aim: To assess endothelial cell selective adhesion molecule (ESAM) as predictor of cardiovascular mortality in diabetic dialysis patients (DDPs)., Methods: ESAM, clinical and laboratory parameters were assessed in 73 DDP. Cardiovascular mortality was recorded in a 2 years' prospective observational study., Results: Baseline ESAM was 17.1 (10.05-24.8) ng/ml and was correlated to phosphate (r = -0.42, p = 0.008), parathormone (r = -0.36, p = 0.048), albumin (r = -0.24, p = 0.048). ESAM significantly predicted cardiovascular death in univariate [HR = 1.03, 95% CI (1.006-1.054), p = 0.01] and multivariate [HR = 1.034, 95% CI (1.003-1.066), p = 0.03] Cox analysis. Time to cardiovascular death was shorter for patients with ESAM >12.44 ng/ml, p = 0.0045., Conclusion: ESAM is an independent predictor of cardiovascular mortality in DDP.
Published: 2015

50. Effect of the early intensive multifactorial therapy on the cardiovascular risk in patients with newly diagnosed type 2 diabetes: an observational, prospective study.

Author: Stefan RM, Nita C, Craciun A, Rusu A, and Hancu N
Abstract: Background and Aims: We assessed if early intensive interventions improve the glycemic control and the modifiable cardiovascular diseases risk factors in Romanian patients with newly diagnosed type-2 diabetes during the first year follow-up period., Patients and Methods: This was an observational, prospective study: 69 subjects were included in the analysis; each of them received intensive multi-factorial pharmacologic treatment and therapeutic education targeting hyperglycemia, weight, hypertension and dyslipidemia. Disease monitoring was done at months 0, 1, 3, 6 and 12 by assessment of anthropometric measurements, arterial blood pressure and biochemical parameters. The cardiovascular diseases risk factors were calculated using the United Kingdom Prospective Diabetes Study Risk Engine., Results: The mean age at diagnosis was 53.61±10.66 years. All anthropometric variables (body weight, body mass index, waist circumference, visceral fat area, percentage of body fat), except for skeletal muscle mass, significantly decreased overtime. The majority of the biochemical parameters significantly decreased overtime. The non-fatal/fatal coronary heart disease risk significantly decreased at month 12 (9.74 [p<0.05] and 4.84 [p<0.05], respectively) compared to month 0 (19.66 and 11.10, respectively); a similar trend of the non-fatal/fatal stroke (risk at month 12, 8.30 [p<0.05] and 1.04 [p<0.05], respectively, while at month 0, 7.89 and 1.38, respectively) was recorded., Conclusions: Early multi-factorial treatment and intensive lifestyle interventions in patients newly diagnosed with type-2 diabetes could decrease with approximately 50% the rate of cardiovascular disease risk.
Published: 2015
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