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2. Identification and management of eating disorders in pregnancy : a multi-method study of maternity and health visiting services

Author

Bye, Amanda Margaret

Subjects
362.1983
Abstract

Pregnant women with current and past eating disorders (ED) have heightened risk of adverse maternal and infant outcomes, so it is imperative women are identified and receive enhanced care during and after pregnancy to promote optimal outcomes. However, following recent changes to the classification of ED, it is unclear how many pregnant women have had ED and research is needed to understand the barriers to their care in maternity and health visiting services. A multi-method approach, comprising of four studies, was employed to: (1) investigate the prevalence of ED in pregnant women; and (2) explore the barriers to care from the perspectives of women, midwives and health visitors. Study one found the prevalence of ED before and during pregnancy were 8.8% and 6.7%, respectively, using a self-report questionnaire in 1,022 pregnant women. Study two estimated population prevalence for lifetime and current ED of 15.3% (95% CI, 11.80-19.71%) and 1.4% (95% CI, 0.64-3.35%), respectively, using diagnostic interviews in 543 pregnant women. Study three, which collated survey data from 103 pregnant and postnatal women, found disclosure of ED was low due to perceptions of poor awareness, stigma, lack of continuity in carer and limited capacity in maternity services. Study four, using a two-phased design with questionnaires (N = 265) and focus groups (N = 33) in midwives and health visitors, found the main barriers to identifying and caring for women with ED were insufficient training and related practice. The findings indicate a significant proportion of pregnant women will have had ED, yet women will often be poorly identified and receive inadequate care in maternity and health visiting services. Future research should aim to develop strategies that address the barriers identified in this research to improve care for pregnant and postnatal women with ED to promote optimal outcomes for mother and child.

Published
2020

3. Prediction for 2-Year Vision Outcomes Using Early Morphologic and Functional Responses in the Comparison of Age-related Macular Degeneration Treatments Trials

Author

Williams, David F., Beardsley, Sara, Bennett, Steven, Cantrill, Herbert, Chan-Tram, Carmen, Cheshier, Holly, Damato, Kathyrn, Davies, John, Dev, Sundeep, Enloe, Julianne, Follano, Gennaro, Gilbert, Peggy, Johnson, Jill, Jones, Tori, Mayleben, Lisa, Mittra, Robert, Moos, Martha, Neist, Ryan, Oestreich, Neal, Quiram, Polly, Ramsay, Robert, Ryan, Edwin, Schindeldecker, Stephanie, Snater, John, Steele, Trenise, Selders, Dwight, Tonsfeldt, Jessica, Valardi, Shelly, Fish, Gary Edd, Aguado, Hank A., Arceneaux, Sally, Arnwine, Jean, Bell, Kim, Bell, Tina, Boleman, Bob, Bradley, Patricia, Callanan, David, Coors, Lori, Creighton, Jodi, Crew, Timothy, Cummings, Kimberly, Dock, Christopher, Duignan, Karen, Fuller, Dwain, Gray, Keith, Hendrix, Betsy, Hesse, Nicholas, Jaramillo, Diana, Jost, Bradley, Lash, Sandy, Lonsdale, Laura, Mackens, Michael, Mutz, Karin, Potts, Michael, Sanchez, Brenda, Snyder, William, Solley, Wayne, Tarter, Carrie, Wang, Robert, Williams, Patrick, Perkins, Stephen L., Anderson, Nicholas, Arnold, Ann, Blais, Paul, Googe, Joseph, Higdon, Tina T., Hunt, Cecile, Johnson, Mary, Miller, James, Moore, Misty, Morris, Charity K., Morris, Christopher, Oelrich, Sarah, Oliver, Kristina, Seitz, Vicky, Whetstone, Jerry, Doft, Bernard H., Bedel, Jay, Bergren, Robert, Borthwick, Ann, Conrad, Paul, Fec, Amanda, Fulwylie, Christina, Ingram, Willia, Latham, Shawnique, Lester, Gina, Liu, Judy, Lobes, Louis, Lucko, Nicole M., Mechling, Holly, Merlotti, Lori, McBroom, Keith, Olsen, Karl, Puskas, Danielle, Rath, Pamela, Schmucker, Maria, Schueckler, Lynn, Schultz, Christina, Shultz, Heather, Steinberg, David, Vyas, Avni, Whale, Kim, Yeckel, Kimberly, Orth, David H., Arredondo, Linda S., Brown, Susan, Ciscato, Barbara J., Civantos, Joseph M., Figliulo, Celeste, Hasan, Sohail, Kosinski, Belinda, Muir, Dan, Nelson, Kiersten, Packo, Kirk, Pollack, John S., Rezaei, Kourous, Shelton, Gina, Townsend-Patrick, Shannya, Walsh, Marian, McDonald, H. Richard, Ansari, Nina, Bye, Amanda, Fu, Arthur D., Grout, Sean, Indermill, Chad, Johnson, Robert N., Jumper, J. Michael, Linares, Silvia, Lujan, Brandon J., Munden, Ames, Persons, Meredith, Rodriguez, Rosa, Rose, Jennifer M., Teske, Brandi, Urias, Yesmin, Young, Stephen, Dreyer, Richard F., Daniel, Howard, Connaughton, Michele, Handelman, Irvin, Hobbs, Stephen, Hoerner, Christine, Hudson, Dawn, Kopfer, Marcia, Lee, Michael, Lemley, Craig, Logan, Joe, Ma, Colin, Mallet, Christophe, Milliron, Amanda, Peters, Mark, Wohlsein, Harry, Pearlman, Joel A., Andrews, Margo, Bartlett, Melissa, Carlson, Nanette, Cox, Emily, Equi, Robert, Gonzalez, Marta, Griffin, Sophia, Hogue, Fran, Kennedy, Lance, Kryuchkov, Lana, Lopez, Carmen, Lopez, Danny, Luevano, Bertha, McKenna, Erin, Patel, Arun, Reed, Brian, Secor, Nyla, Sison, Iris R., Tsai, Tony, Varghis, Nina, Waller, Brooke, Wendel, Robert, Yebra, Reina, Roth, Daniel B., Deinzer, Jane, Fine, Howard, Green, Flory, Green, Stuart, Keyser, Bruce, Leff, Steven, Leviton, Amy, Martir, Amy, Mosenthine, Kristin, Muscle, Starr, Okoren, Linda, Parker, Sandy, Prenner, Jonathan, Price, Nancy, Rogers, Deana, Rosas, Linda, Schlosser, Alex, Studenko, Loretta, Tantum, Thea, Wheatley, Harold, Trese, Michael T., Aaberg, Thomas, Bezaire, Denis, Bridges, Craig, Bryant, Doug, Capone, Antonio, Coleman, Michelle, Consolo, Christina, Cook, Cindy, DuLong, Candice, Garretson, Bruce, Grooten, Tracy, Hammersley, Julie, Hassan, Tarek, Jessick, Heather, Jones, Nanette, Kinsman, Crystal, Krumlauf, Jennifer, Lewis, Sandy, Locke, Heather, Margherio, Alan, Markus, Debra, Marsh, Tanya, Neal, Serena, Noffke, Amy, Oh, Kean, Pence, Clarence, Preston, Lisa, Raphaelian, Paul, Regan, Virginia R., Roberts, Peter, Ruby, Alan, Sarrafizadeh, Ramin, Scherf, Marissa, Scott, Sarita, Sneed, Scott, Staples, Lisa, Terry, Brad, Trese, Matthew T., Videtich, Joan, Williams, George, Zajechowski, Mary, Joseph, Daniel P., Blinder, Kevin, Boyd, Lynda, Buckley, Sarah, Crow, Meaghan, Dinatale, Amanda, Engelbrecht, Nicholas, Forke, Bridget, Gabel, Dana, Grand, Gilbert, Grillion-Cerone, Jennifer, Holekamp, Nancy, Kelly, Charlotte, Nobel, Ginny, Pepple, Kelly, Raeber, Matt, Rao, P. Kumar, Ressel, Tammy, Schremp, Steven, Sgorlon, Merrilee, Shears, Shantia, Thomas, Matthew, Timma, Cathy, Vaughn, Annette, Walters, Carolyn, Weeks, Rhonda, Wehmeier, Jarrod, Wright, Tim, Berinstein, Daniel M., Ayyad, Aida, Barazi, Mohammed K., Bickhart, Erica, Brady, Tracey, Byank, Lisa, Cronise, Alysia, Denny, Vanessa, Dunn, Courtney, Flory, Michael, Frantz, Robert, Garfinkel, Richard A., Gilbert, William, Lai, Michael M., Melamud, Alexander, Newgen, Janine, Newton, Shamekia, Oliver, Debbie, Osman, Michael, Sanders, Reginald, von Fricken, Manfred, Dugel, Pravin, Arenas, Sandra, Balea, Gabe, Bartoli, Dayna, Bucci, John, Cornelius, Jennifer A., Dickens, Scheleen, Doherty, Don, Dunlap, Heather, Goldenberg, David, Jamal, Karim, Jimenez, Norma, Kavanagh, Nicole, Kunimoto, Derek, Martin, John, Miner, Jessica, Mobley, Sarah, Park, Donald, Quinlan, Edward, Sipperley, Jack, Slagle, Carol, Smith, Danielle, Yafchak, Miguelina, Yager, Rohana, Flaxel, Christina J., Bailey, Steven, Francis, Peter, Howell, Chris, Hwang, Thomas, Ira, Shirley, Klein, Michael, Lauer, Andreas, Liesegang, Teresa, Lundquist, Ann, Nolte, Sarah, Nolte, Susan K., Pickell, Scott, Pope, Susan, Rossi, Joseph, Schain, Mitchell, Steinkamp, Peter, Toomey, Maureen D., Vahrenwald, Debora, West, Kelly, Hubbard, Baker, Andelman, Stacey, Bergstrom, Chris, Brower, Judy, Cribbs, Blaine, Curtis, Linda, Dobbs, Jannah, DuBois, Lindreth, Gaultney, Jessica, Gibbs, Deborah, Jordan, Debora, Leef, Donna, Martin, Daniel F., Myles, Robert, Olsen, Timothy, Schwent, Bryan, Srivastava, Sunil, Waldron, Rhonda, Antoszyk, Andrew N., Balasubramaniam, Uma, Brooks, Danielle, Brown, Justin, Browning, David, Clark, Loraine, Ennis, Sarah, Held, Susannah, Helms, Jennifer V., Herby, Jenna, Karow, Angie, Leotaud, Pearl, Massimino, Caterina, McClain, Donna, McOwen, Michael, Mindel, Jennifer, Pereira, Candace, Pierce, Rachel, Powers, Michele, Price, Angela, Rohrer, Jason, Sanders, Jason, Avery, Robert L., Avery, Kelly, Basefsky, Jessica, Beckner, Liz, Castellarin, Alessandro, Couvillion, Stephen, Giust, Jack, Giust, Matthew, Nasir, Maan, Pieramici, Dante, Rabena, Melvin, Risard, Sarah, See, Robert, Smith, Jerry, Wan, Lisha, Bakri, Sophie J., Abu-Yaghi, Nakhleh, Barkmeier, Andrew, Berg, Karin, Burrington, Jean, Edwards, Albert, Goddard, Shannon, Howard, Shannon, Iezzi, Raymond, Lewison, Denise, Link, Thomas, McCannel, Colin A., Overend, Joan, Pach, John, Ruszczyk, Margaret, Shultz, Ryan, Stephan, Cindy, Vogen, Diane, Bradford, Reagan H., Jr., Bergman, Vanessa, Burris, Russ, Butt, Amanda, Daniels, Beth, Dwiggins, Connie, Fransen, Stephen, Guerrero, Tiffany, Haivala, Darin, Harris, Amy, Icks, Sonny, Kingsley, Ronald, Redden, Lena, Richmond, Rob, Ross, Brittany, White, Kammerin, Youngberg, Misty, Topping, Trexler M., Bennett, Steve, Chong, Sandy, Ciotti, Mary, Cleary, Tina, Corey, Emily, Donovan, Dennis, Frederick, Albert, Freese, Lesley, Graham, Margaret, Gud, Natalya, Howard, Taneika, Jones, Mike, Morley, Michael, Moses, Katie, Stone, Jen, Ty, Robin, Wiegand, Torsten, Williams, Lindsey, Winder, Beth, Awh, Carl C., Amonette, Michelle, Arrindell, Everton, Beck, Dena, Busbee, Brandon, Dilback, Amy, Downs, Sara, Guidry, Allison, Gutow, Gary, Hardin, Jackey, Hines, Sarah, Hutchins, Emily, LaCivita, Kim, Lester, Ashley, Malott, Larry, McCain, MaryAnn, Miracle, Jayme, Moffat, Kenneth, Palazzotta, Lacy, Robinson, Kelly, Sonkin, Peter, Travis, Alecia, Wallace, Roy Trent, Winters, Kelly J., Wray, Julia, Harris, April E., Bunnell, Mari, Crooks, Katrina, Fitzgerald, Rebecca, Javid, Cameron, Kew, Corin, Kill, Erica, Kline, Patricia, Kreienkamp, Janet, Martinez, Maricruz, Moore, Roy Ann, Saavedra, Egbert, Taylor, LuAnne, Walsh, Mark, Wilson, Larry, Ciulla, Thomas A., Coyle, Ellen, Harrington, Tonya, Harris, Charlotte, Hood, Cindi, Kerr, Ingrid, Maturi, Raj, Moore, Dawn, Morrow, Stephanie, Savage, Jennifer, Sink, Bethany, Steele, Tom, Thukral, Neelam, Wilburn, Janet, Walker, Joseph P., Banks, Jennifer, Ciampaglia, Debbie, Dyshanowitz, Danielle, Frederick, Jennifer, Ghuman, A. Tom, Grodin, Richard, Kiesel, Cheryl, Knips, Eileen, McCue, Jonathan, Ortiz, Maria, Peters, Crystal, Raskauskas, Paul, Schoeman, Etienne, Sharma, Ashish, Wing, Glenn, Youngblood, Rebecca, Chandra, Suresh R., Altaweel, Michael, Blodi, Barbara, Burke, Kathryn, Dietzman, Kristine A., Gottlieb, Justin, Knutson, Gene, Krolnik, Denise, Nork, T. Michael, Olson, Shelly, Peterson, John, Reed, Sandra, Soderling, Barbara, Somers, Guy, Stevens, Thomas, Wealti, Angela, Bearelly, Srilaxmi, Branchaud, Brenda, Bryant, Joyce W., Crowell, Sara, Fekrat, Sharon, Gammage, Merritt, Harrison, Cheala, Jones, Sarah, McClain, Noreen, McCuen, Brooks, Mruthyunjaya, Prithvi, Queen, Jeanne, Sarin, Neeru, Skalak, Cindy, Skelly, Marriner, Suner, Ivan, Tomany, Ronnie, Welch, Lauren, Park, Susanna S., Cassidy, Allison, Chandra, Karishma, Good, Idalew, Imson, Katrina, Sashi, Kaur, Metzler, Helen, Morse, Lawrence, Redenbo, Ellen, Salvador, Marisa, Telander, David, Thomas, Mark, Wallace, Cindy, Barr, Charles C., Battcher, Amanda, Bottorff, Michelle, Chasteen, Mary, Clark, Kelly, Denning, Diane, Schoen, Debra, Schultz, Amy, Tempel, Evie, Wheeler, Lisa, Whittington, Greg K., Stone, Thomas W., Blevins, Todd, Buck, Michelle, Cruz, Lynn, Heath, Wanda, Holcomb, Diana, Isernhagen, Rick, Kidd, Terri, Kitchens, John, Sears, Cathy, Slade, Ed, Van Arsdall, Jeanne, VanHoose, Brenda, Wolfe, Jenny, Wood, William, Zilis, John, Crooks, Carol, Disney, Larry, Liu, Mimi, Petty, Stephen, Sall, Sandra, Folk, James C., Aly, Tracy, Brotherton, Abby, Critser, Douglas, Hinz, Connie J., Karakas, Stefani, Kirschner, Valerie, Lester, Cheyanne, Montague, Cindy, Russell, Stephen, Stockman, Heather, Taylor, Barbara, Verdick, Randy, Walshire, Jean, Thompson, John T., Connell, Barbara, Constantine, Maryanth, Davis, John L., Jr., Gwen Holsapple, Hunter, Lisa, Lenane, C. Nicki, Mitchell, Robin, Russel, Leslie, Sjaarda, Raymond, Brown, David M., Benz, Matthew, Burns, Llewellyn, Carranza, JoLene G., Fish, Richard, Goates, Debra, Hay, Shayla, Jeffers, Theresa, Kegley, Eric, Kubecka, Dallas, McGilvra, Stacy, Richter, Beau, Sneed, Veronica, Stoever, Cary, Tellez, Isabell, Wong, Tien, Kim, Ivana, Andreoli, Christopher, Barresi, Leslie, Brett, Sarah, Callahan, Charlene, Capaccioli, Karen, Carli, William, Coppola, Matthew, Emmanuel, Nicholas, Evans, Claudia, Fagan, Anna, Grillo, Marcia, Head, John, Kieser, Troy, Lee, Elaine, Lord, Ursula, Miretsky, Edward, Palitsch, Kate, Petrin, Todd, Reader, Liz, Reznichenko, Svetlana, Robertson, Mary, Smith, Justin, Vavvas, Demetrios, Wells, John, Cahill, Cassie, Clark, W. Lloyd, Henry, Kayla, Johnson, David, Miller, Peggy, Oliver, LaDetrick, Spivey, Robbin, Swinford, Tiffany, Taylor, Mallie, Lambert, Michael, Chase, Kris, Fredrickson, Debbie, Khawly, Joseph, Lazarte, Valerie, Lowd, Donald, Miller, Pam, Willis, Arthur, Ferrone, Philip J., Almonte, Miguel, Arnott, Rachel, Aviles, Ingrid, Carbon, Sheri, Chitjian, Michael, DAmore, Kristen, Elliott, Christin, Fastenberg, David, Golub, Barry, Graham, Kenneth, Lavorna, AnnMarie, Murphy, Laura, Palomo, Amanda, Puglisi, Christina, Rhee, David, Romero, Juan, Rosenblatt, Brett, Salcedo, Glenda, Schlameuss, Marianne, Shakin, Eric, Sookhai, Vasanti, Kaiser, Richard, Affel, Elizabeth, Brown, Gary, Centinaro, Christina, Fine, Deborah, Fineman, Mitchell, Formoso, Michele, Garg, Sunir, Grande, Lisa, Herbert, Carolyn, Ho, Allen, Hsu, Jason, Jay, Maryann, Lavetsky, Lisa, Liebenbaum, Elaine, Maguire, Joseph, Monsonego, Julia, O’Connor, Lucia, Pierce, Lisa, Regillo, Carl, Rosario, Maria, Spirn, Marc, Vander, James, Walsh, Jennifer, Davidorf, Frederick H., Barnett, Amanda, Chang, Susie, Christoforidis, John, Elliott, Joy, Justice, Heather, Letson, Alan, McKinney, Kathryne, Perry, Jeri, Salerno, Jill A., Savage, Scott, Shelley, Stephen, Singerman, Lawrence J., Coney, Joseph, DuBois, John, DuBois, Kimberly, Greanoff, Gregg, Himmelman, Dianne, Ilc, Mary, McNamara, Elizabeth, Novak, Michael, Pendergast, Scott, Rath, Susan, Smith-Brewer, Sheila, Tanner, Vivian, Weiss, Diane E., Zegarra, Hernando, Halperin, Lawrence, Aramayo, Patricia, Dhalla, Mandeep, Fernandez, Brian, Fernandez, Cindy, Lopez, Jaclyn, Lopez, Monica, Mariano, Jamie, Murphy, Kellie, Sherley, Clifford, Veksler, Rita, Rahhal, Firas, Babikian, Razmig, Boyer, David, Hami, Sepideh, Kessinger, Jeff, Kurokouchi, Janet, Mukarram, Saba, Pachman, Sarah, Protacio, Eric, Sierra, Julio, Tabandeh, Homayoun, Zamboni, Adam, Elman, Michael, Belz, Jennifer, Butcher, Tammy, Cain, Theresa, Coffey, Teresa, Firestone, Dena, Gore, Nancy, Singletary, Pamela, Sotirakos, Peter, Starr, JoAnn, Meredith, Travis A., Barnhart, Cassandra J., Cantrell, Debra, Esquejo-Leon, RonaLyn, Houghton, Odette, Kaur, Harpreet, NDure, Fatoumatta, Glatzer, Ronald, Joffe, Leonard, Schindler, Reid, Xue, Katie, Hua, Peiying, Maguire, Maureen G., Daniel, Ebenezer, Jaffe, Glenn J., Grunwald, Juan E., and Ying, Gui-shuang

Published
2023
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4. Cohort profile: The Social media, smartphone use and Self-harm in Young People (3S-YP) study–A prospective, observational cohort study of young people in contact with mental health services

Author

Bye, Amanda, primary, Carter, Ben, additional, Leightley, Daniel, additional, Trevillion, Kylee, additional, Liakata, Maria, additional, Branthonne-Foster, Stella, additional, Cross, Samantha, additional, Zenasni, Zohra, additional, Carr, Ewan, additional, Williamson, Grace, additional, Vega Viyuela, Alba, additional, and Dutta, Rina, additional

Published
2024
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5. Lifestyle: Weight

Author

Bogaerts, Annick, Bye, Amanda, Bijlholt, Margriet, Maslin, Kate, Devlieger, Roland, Shawe, Jill, editor, Steegers, Eric A.P., editor, and Verbiest, Sarah, editor

Published
2020
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9. Brenna's Story: A Critical Reflection and Analysis of One Mother's Experience of Navigating the Medical System with a Child with Intellectual Disabilities

Author

Bye, Amanda and Aston, Megan

Abstract

Children with intellectual disabilities spend more time in the health-care system than mainstream children. Parents have to learn how to navigate the system by coordinating appointments, understanding the referral process, knowing what services are available, and advocating for those services. This places an incredible amount of responsibility on families. This article is one mother's personal story and reflection about her journey through the Canadian health-care system in Nova Scotia, with her daughter who has an intellectual disability. The reflection identifies moments of tension experienced by a mother and how she was expected to be a medical system navigator, doctor-educator, time manager, and care coordinator and the roles that led to feelings of repression, extreme frustration, and fear. A final discussion offers an analysis of her experience, using concepts from feminist post-structuralism.

Published
2016
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10. Effect of maternal eating disorders on mother-infant quality of interaction, bonding and child temperament:A longitudinal study

Author

Martini, Maria Giulia, Taborelli, Emma, Easter, Abigail, Bye, Amanda, Eisler, Ivan, Schmidt, Ulrike, Micali, Nadia, Martini, Maria Giulia, Taborelli, Emma, Easter, Abigail, Bye, Amanda, Eisler, Ivan, Schmidt, Ulrike, and Micali, Nadia

Abstract

Aims: This study aims to investigate the effect of maternal eating disorders (ED) on mother-infant quality of interaction at 8 weeks and bonding and child temperament at 1 and 2 years postnatally. We also aimed to explore the relationship between maternal ED psychopathology, comorbid psychiatric difficulties, and both mother-infant quality of interaction and bonding in women with ED. Women were recruited to a prospective longitudinal study. By the time of giving birth, the sample consisted of 101 women of the initial 137 (73.7%). Overall, 62 women (ED = 36; HC = 26) participated in the 8-week assessment, 42 (ED = 20; HC = 22) at 1 year, and 78 (ED = 34; HC = 44) at 2 years. Mann-Whitney U Test was used to explore association between maternal ED and mother-infant quality of interaction and between maternal ED and bonding. Spearman correlations were used to explore associations between maternal ED psychopathology, comorbid psychiatric difficulties, and both mother-infant quality of interaction and bonding. Results: We found no differences between early mother-infant interaction and bonding in mothers with ED in comparison to HC. High levels of maternal ED psychopathology were correlated with high anxiety levels, higher negative affectivity, and lower extraversion in children of ED mothers both at 1 and 2 years. Furthermore, high levels of ED psychopathology were also associated with lower effortful control at 1 year. Conclusions: Findings imply that maternal ED have an impact on child temperament. Future research should focus on resilience and on which protective factors might lead to positive outcomes. These factors can be then used as therapeutic and preventative targets.

Published
2023

18. Perinatal mental health services in pregnancy and the year after birth: the ESMI research programme including RCT

Author

Howard, Louise M, primary, Abel, Kathryn M, additional, Atmore, Katie H, additional, Bick, Debra, additional, Bye, Amanda, additional, Byford, Sarah, additional, Carson, Lauren E, additional, Dolman, Clare, additional, Heslin, Margaret, additional, Hunter, Myra, additional, Jennings, Stacey, additional, Johnson, Sonia, additional, Jones, Ian, additional, Taylor, Billie Lever, additional, McDonald, Rebecca, additional, Milgrom, Jeannette, additional, Morant, Nicola, additional, Nath, Selina, additional, Pawlby, Susan, additional, Potts, Laura, additional, Powell, Claire, additional, Rose, Diana, additional, Ryan, Elizabeth, additional, Seneviratne, Gertrude, additional, Shallcross, Rebekah, additional, Stanley, Nicky, additional, Trevillion, Kylee, additional, Wieck, Angelika, additional, and Pickles, Andrew, additional

Published
2022
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20. Perinatal mental health services in pregnancy and the year after birth: the ESMI research programme including RCT

Author

Howard, Louise M, Abel, Kathryn M, Atmore, Katie H, Bick, Debra, Bye, Amanda, Byford, Sarah, Carson, Lauren E, Dolman, Clare, Heslin, Margaret, Hunter, Myra, Jennings, Stacey, Johnson, Sonia, Jones, Ian, Taylor, Billie Lever, McDonald, Rebecca, Milgrom, Jeannette, Morant, Nicola, Nath, Selina, Pawlby, Susan, Potts, Laura, Powell, Claire, Rose, Diana, Ryan, Elizabeth, Seneviratne, Gertrude, Shallcross, Rebekah, Stanley, Nicky, Trevillion, Kylee, Wieck, Angelika, Pickles, Andrew, Howard, Louise M, Abel, Kathryn M, Atmore, Katie H, Bick, Debra, Bye, Amanda, Byford, Sarah, Carson, Lauren E, Dolman, Clare, Heslin, Margaret, Hunter, Myra, Jennings, Stacey, Johnson, Sonia, Jones, Ian, Taylor, Billie Lever, McDonald, Rebecca, Milgrom, Jeannette, Morant, Nicola, Nath, Selina, Pawlby, Susan, Potts, Laura, Powell, Claire, Rose, Diana, Ryan, Elizabeth, Seneviratne, Gertrude, Shallcross, Rebekah, Stanley, Nicky, Trevillion, Kylee, Wieck, Angelika, and Pickles, Andrew

Abstract

Background It is unclear how best to identify and treat women with mental disorders in pregnancy and the year after birth (i.e. the perinatal period). Objectives (1) To investigate how best to identify depression at antenatal booking [work package (WP) 1]. (2) To estimate the prevalence of mental disorders in early pregnancy (WP1). (3) To develop and examine the efficacy of a guided self-help intervention for mild to moderate antenatal depression delivered by psychological well-being practitioners (WP1). (4) To examine the psychometric properties of the perinatal VOICE (Views On Inpatient CarE) measure of service satisfaction (WP3). (5) To examine the clinical effectiveness and cost-effectiveness of services for women with acute severe postnatal mental disorders (WPs 1–3). (6) To investigate women’s and partners’/significant others’ experiences of different types of care (WP2). Design Objectives 1 and 2 – a cross-sectional survey stratified by response to Whooley depression screening questions. Objective 3 – an exploratory randomised controlled trial. Objective 4 – an exploratory factor analysis, including test–retest reliability and validity assessed by association with the Client Satisfaction Questionnaire contemporaneous satisfaction scores. Objective 5 – an observational cohort study using propensity scores for the main analysis and instrumental variable analysis using geographical distance to mother and baby unit. Objective 6 – a qualitative study. Setting English maternity services and generic and specialist mental health services for pregnant and postnatal women. Participants Staff and users of mental health and maternity services. Interventions Guided self-help, mother and baby units and generic care. Main outcome measures The following measures were evaluated in WP1(i) – specificity, sensitivity, positive predictive value, likelihood ratio, acceptability and population prevalence estimates. The following measures were evaluated in WP1(ii) – participant recr

Published
2022

21. Effect of maternal eating disorders on mother‐infant quality of interaction, bonding and child temperament: A longitudinal study.

Author

Martini, Maria Giulia, Taborelli, Emma, Easter, Abigail, Bye, Amanda, Eisler, Ivan, Schmidt, Ulrike, and Micali, Nadia

Subjects
MEDICAL quality control, PSYCHOANALYTIC theory, STATISTICS, PSYCHOLOGY of mothers, MOTHER-infant relationship, MANN Whitney U Test, PARENT-infant relationships, MOTHERHOOD, PARENTING, COMPARATIVE studies, TEMPERAMENT, PATHOLOGICAL psychology, DESCRIPTIVE statistics, DATA analysis, LONGITUDINAL method, EATING disorders
Abstract

Aims: This study aims to investigate the effect of maternal eating disorders (ED) on mother‐infant quality of interaction at 8 weeks and bonding and child temperament at 1 and 2 years postnatally. We also aimed to explore the relationship between maternal ED psychopathology, comorbid psychiatric difficulties, and both mother‐infant quality of interaction and bonding in women with ED. Women were recruited to a prospective longitudinal study. By the time of giving birth, the sample consisted of 101 women of the initial 137 (73.7%). Overall, 62 women (ED = 36; HC = 26) participated in the 8‐week assessment, 42 (ED = 20; HC = 22) at 1 year, and 78 (ED = 34; HC = 44) at 2 years. Mann‐Whitney U Test was used to explore association between maternal ED and mother‐infant quality of interaction and between maternal ED and bonding. Spearman correlations were used to explore associations between maternal ED psychopathology, comorbid psychiatric difficulties, and both mother‐infant quality of interaction and bonding. Results: We found no differences between early mother‐infant interaction and bonding in mothers with ED in comparison to HC. High levels of maternal ED psychopathology were correlated with high anxiety levels, higher negative affectivity, and lower extraversion in children of ED mothers both at 1 and 2 years. Furthermore, high levels of ED psychopathology were also associated with lower effortful control at 1 year. Conclusions: Findings imply that maternal ED have an impact on child temperament. Future research should focus on resilience and on which protective factors might lead to positive outcomes. These factors can be then used as therapeutic and preventative targets. Key points: Our study did not find significant differences in each domain of mother‐infant quality of interaction and bonding between cases and controls.Positive correlations were found between high levels of maternal ED psychopathology, anxiety, and high levels of negative affectivity, and lower extraversion in children at both 1 and 2 years, and ED psychopathology and lower effortful control at 1 year.Children's temperament is compromised in the presence of a maternal eating disorder. Detection and early intervention are recommended to facilitate mother‐child interactions and to prevent any later adverse outcomes. [ABSTRACT FROM AUTHOR]

Published
2023
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23. Prevalence of eating disorders in pregnant women

Author

Bye, Amanda, Nath, Selina, Ryan, Elizabeth G., Bick, Debra, Easter, Abigail, Howard, Louise M., and Micali, Nadia

Subjects
RG, RA, RC
Abstract

Objective\ud To estimate prevalence of lifetime and current eating disorders (ED) in a sample of pregnant women in South‐East London and to describe their sociodemographic and clinical characteristics.\ud \ud Method\ud Secondary analysis of data from a cross‐sectional survey. Using a stratified sampling design, 545 pregnant women were recruited. Diagnostic interviews were administered to assess lifetime and current ED, depression, anxiety, and borderline personality disorder. Data were extracted from maternity records to assess identification of ED in antenatal care. Estimates of population prevalence of ED were obtained using sampling weights to account for the stratified sampling design.\ud \ud Results\ud Weighted prevalence of lifetime ED was 15.35% (95% confidence interval [CI] [11.80, 19.71]), and current ED was 1.47% (95% CI [0.64, 3.35]). Depression, anxiety, and history of deliberate self‐harm or attempted suicide were common in pregnant women with ED. Identification of ED in antenatal care was low.\ud \ud Conclusions\ud Findings indicate that by early pregnancy, a significant proportion of pregnant women will have had ED, although less typically during pregnancy, and psychiatric comorbidity is common. Yet ED were poorly recognised in antenatal care. The findings highlight the importance of increasing awareness about maternal ED to improve identification and response to the healthcare needs of pregnant women with ED.

Published
2020

27. Snap shot: Achieving better care through a one-page personal health profile.

Author

Aston, Megan, Sweet, Krista, McAfee, Erin, Price, Sheri, Sheriko, Jordan, Monaghan, Joelle, Filliter, Jillian, Walls, Cathy, McGrath, Patrick, Vanderlee, Emma, and Bye, Amanda

Subjects
INTELLECTUAL disabilities, CHILD psychology, MEDICAL personnel, FAMILIES, QUALITATIVE research, COMMUNICATION, PEOPLE with intellectual disabilities, PARENTS
Abstract

Children with intellectual disabilities (IDs) can have complex health conditions that require intense and ongoing care management by multiple healthcare professionals (HCPs). Families often experience frustrations and challenges sharing necessary information about their children's unique emotional and communicative needs with HCPs. In turn, these needs are often poorly documented and shared with other HCPs. This contributes to compromised care and frustrations for families and HCPs. We conducted a qualitative study using focus groups to examine how 10 parents and 3 HCPs experienced provision of care for children with ID, as well as their suggestions for developing a one-page personal health profile (PHP) to improve communication. Parents suggested including behavioural descriptors rather than diagnoses. All participants believed a one-page PHP that was child and parent led would be very helpful and would improve communication between HCPs, parents and children leading to effective and supportive care. [ABSTRACT FROM AUTHOR]

Published
2021
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28. Barriers to identifying eating disorders in pregnancy and in the postnatal period:A qualitative approach

Author

Bye, Amanda, Shawe, Jill, Bick, Debra, Easter, Abigail, Kash-Macdonald, Megan, and Micali, Nadia

Subjects
Adult, Health Knowledge, Attitudes, Practice, Identification, Attitude of Health Personnel, Health Personnel, Eating Disorders, Social Stigma, Disclosure, Midwifery, lcsh:Gynecology and obstetrics, Feeding and Eating Disorders, Young Adult, ddc:616.89, Pregnancy, Qualitative research, Humans, lcsh:RG1-991, Postpartum Period, Focus Groups, United Kingdom, Pregnancy Complications, Female, Perception, Pregnant Women, Barriers, Research Article
Abstract

Background Eating Disorders (ED) are mental health disorders that typically effect women of childbearing age and are associated with adverse maternal and infant outcomes. UK healthcare guidance recommends routine enquiry for current and past mental illness in antenatal and postnatal care for all women, and that pregnant women with a known ED are offered enhanced monitoring and support. Midwives and health visitors are ideally placed to identify and support women with ED as they are often the primary point of contact during the antenatal and postnatal periods. However, research on the barriers to identifying ED in the perinatal period is limited. This study aimed to understand the barriers to disclosure and identification of ED in pregnancy and postnatally as perceived by women with past or current ED, and midwives and health visitors working in the UK National Health Service. Methods Two studies were undertaken: mixed-measures survey of pregnant and postnatal women with current or past ED; focus groups with student and qualified midwives and health visitors. Results Five themes emerged on the barriers to disclosure in pregnancy as perceived by women: stigma, lack of opportunity, preference for self-management, current ED symptomatology and illness awareness. Four themes were identified on the barriers to identification of ED in pregnancy and in the postnatal period as perceived by health professionals: system constraints, recognition of role, personal attitudes, and stigma and taboo. Conclusions Several barriers to the identification of ED during and after pregnancy were described, the main factors were stigma and poor professional training. Perinatal mental health is becoming increasingly prioritised within national policy initiatives; however, ED continue to be neglected and increased awareness is needed. Similarly, clinical guidance aimed at responding to the rising prevalence of obesity focus on changing nutrition but not on assessing for the presence of ED behaviours that might be affecting nutrition. Improving education and training for health professionals may contribute to reducing stigma and increase confidence in identifying ED. The barriers identified in this research need to be addressed if recognition and response to women with ED during the perinatal period is to improve. Electronic supplementary material The online version of this article (10.1186/s12884-018-1745-x) contains supplementary material, which is available to authorized users.

Published
2018

34. Understanding and supporting women with eating disorders: Pregnancy, birth, and motherhood.

Author

Easter, Abigail and Bye, Amanda

Subjects
EATING disorders in women, MENTAL health services, PERINATAL period, PREGNANT women, PREGNANCY, MOTHERHOOD
Abstract

Approximately 5% of women will experience an eating disorder during pregnancy (Martínez-Olcina et al., 2020), and around 15% of women at some point prior to pregnancy (Bye et al., 2020). The transition to parenthood can be a challenging time for women with eating disorders, who can experience a greater risk of adverse obstetric outcomes, higher levels of depression and anxiety, and difficulties with infant feeding. Current clinical guidance and good practice recommendations in the UK emphasise the need for early identification of women with eating disorders, and additional support throughout pregnancy and the postnatal period. Women may benefit from a having a nominated healthcare professional throughout the perinatal period, sensitive support around managing nutrition and weight during pregnancy, additional fetal growth scans, signposting to voluntary organisations, and where necessary, referral to specialist eating disorder or perinatal mental health services. [ABSTRACT FROM AUTHOR]

Published
2021

37. Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials

Author

Willoughby, Alex S., primary, Ying, Gui-shuang, additional, Toth, Cynthia A., additional, Maguire, Maureen G., additional, Burns, Russell E., additional, Grunwald, Juan E., additional, Daniel, Ebenezer, additional, Jaffe, Glenn J., additional, Williams, David F., additional, Beardsley, Sara, additional, Bennett, Steven, additional, Cantrill, Herbert, additional, Chan-Tram, Carmen, additional, Cheshier, Holly, additional, Damato, Kathyrn, additional, Davies, John, additional, Dev, Sundeep, additional, Enloe, Julianne, additional, Follano, Gennaro, additional, Gilbert, Peggy, additional, Johnson, Jill, additional, Jones, Tori, additional, Mayleben, Lisa, additional, Mittra, Robert, additional, Moos, Martha, additional, Neist, Ryan, additional, Oestreich, Neal, additional, Quiram, Polly, additional, Ramsay, Robert, additional, Ryan, Edwin, additional, Schindeldecker, Stephanie, additional, Snater, John, additional, Steele, Trenise, additional, Selders, Dwight, additional, Tonsfeldt, Jessica, additional, Valardi, Shelly, additional, Fish, Gary Edd, additional, Aguado, Hank A., additional, Arceneaux, Sally, additional, Arnwine, Jean, additional, Bell, Kim, additional, Bell, Tina, additional, Boleman, Bob, additional, Bradley, Patricia, additional, Callanan, David, additional, Coors, Lori, additional, Creighton, Jodi, additional, Crew, Timothy, additional, Cummings, Kimberly, additional, Dock, Christopher, additional, Duignan, Karen, additional, Fuller, Dwain, additional, Gray, Keith, additional, Hendrix, Betsy, additional, Hesse, Nicholas, additional, Jaramillo, Diana, additional, Jost, Bradley, additional, Lash, Sandy, additional, Lonsdale, Laura, additional, Mackens, Michael, additional, Mutz, Karin, additional, Potts, Michael, additional, Sanchez, Brenda, additional, Snyder, William, additional, Solley, Wayne, additional, Tarter, Carrie, additional, Wang, Robert, additional, Williams, Patrick, additional, Perkins, Stephen L., additional, Anderson, Nicholas, additional, Arnold, Ann, additional, Blais, Paul, additional, Googe, Joseph, additional, Higdon, Tina T., additional, Hunt, Cecile, additional, Johnson, Mary, additional, Miller, James, additional, Moore, Misty, additional, Morris, Charity K., additional, Morris, Christopher, additional, Oelrich, Sarah, additional, Oliver, Kristina, additional, Seitz, Vicky, additional, Whetstone, Jerry, additional, Doft, Bernard H., additional, Bedel, Jay, additional, Bergren, Robert, additional, Borthwick, Ann, additional, Conrad, Paul, additional, Fec, Amanda, additional, Fulwylie, Christina, additional, Ingram, Willia, additional, Latham, Shawnique, additional, Lester, Gina, additional, Liu, Judy, additional, Lobes, Louis, additional, Lucko, Nicole M., additional, Mechling, Holly, additional, Merlotti, Lori, additional, McBroom, Keith, additional, Olsen, Karl, additional, Puskas, Danielle, additional, Rath, Pamela, additional, Schmucker, Maria, additional, Schueckler, Lynn, additional, Schultz, Christina, additional, Shultz, Heather, additional, Steinberg, David, additional, Vyas, Avni, additional, Whale, Kim, additional, Yeckel, Kimberly, additional, Orth, David H., additional, Arredondo, Linda S., additional, Brown, Susan, additional, Ciscato, Barbara J., additional, Civantos, Joseph M., additional, Figliulo, Celeste, additional, Hasan, Sohail, additional, Kosinski, Belinda, additional, Muir, Dan, additional, Nelson, Kiersten, additional, Packo, Kirk, additional, Pollack, John S., additional, Rezaei, Kourous, additional, Shelton, Gina, additional, Townsend-Patrick, Shannya, additional, Walsh, Marian, additional, Richard McDonald, H., additional, Ansari, Nina, additional, Bye, Amanda, additional, Fu, Arthur D., additional, Grout, Sean, additional, Indermill, Chad, additional, Johnson, Robert N., additional, Michael Jumper, J., additional, Linares, Silvia, additional, Lujan, Brandon J., additional, Munden, Ames, additional, Persons, Meredith, additional, Rodriguez, Rosa, additional, Rose, Jennifer M., additional, Teske, Brandi, additional, Urias, Yesmin, additional, Young, Stephen, additional, Dreyer, Richard F., additional, Daniel, Howard, additional, Connaughton, Michele, additional, Handelman, Irvin, additional, Hobbs, Stephen, additional, Hoerner, Christine, additional, Hudson, Dawn, additional, Kopfer, Marcia, additional, Lee, Michael, additional, Lemley, Craig, additional, Logan, Joe, additional, Ma, Colin, additional, Mallet, Christophe, additional, Milliron, Amanda, additional, Peters, Mark, additional, Wohlsein, Harry, additional, Pearlman, Joel A., additional, Andrews, Margo, additional, Bartlett, Melissa, additional, Carlson, Nanette, additional, Cox, Emily, additional, Equi, Robert, additional, Gonzalez, Marta, additional, Griffin, Sophia, additional, Hogue, Fran, additional, Kennedy, Lance, additional, Kryuchkov, Lana, additional, Lopez, Carmen, additional, Lopez, Danny, additional, Luevano, Bertha, additional, McKenna, Erin, additional, Patel, Arun, additional, Reed, Brian, additional, Secor, Nyla, additional, Sison, Iris R., additional, Tsai, Tony, additional, Varghis, Nina, additional, Waller, Brooke, additional, Wendel, Robert, additional, Yebra, Reina, additional, Roth, Daniel B., additional, Deinzer, Jane, additional, Fine, Howard, additional, Green, Flory, additional, Green, Stuart, additional, Keyser, Bruce, additional, Leff, Steven, additional, Leviton, Amy, additional, Martir, Amy, additional, Mosenthine, Kristin, additional, Muscle, Starr, additional, Okoren, Linda, additional, Parker, Sandy, additional, Prenner, Jonathan, additional, Price, Nancy, additional, Rogers, Deana, additional, Rosas, Linda, additional, Schlosser, Alex, additional, Studenko, Loretta, additional, Tantum, Thea, additional, Wheatley, Harold, additional, Trese, Michael T., additional, Aaberg, Thomas, additional, Bezaire, Denis, additional, Bridges, Craig, additional, Bryant, Doug, additional, Capone, Antonio, additional, Coleman, Michelle, additional, Consolo, Christina, additional, Cook, Cindy, additional, DuLong, Candice, additional, Garretson, Bruce, additional, Grooten, Tracy, additional, Hammersley, Julie, additional, Hassan, Tarek, additional, Jessick, Heather, additional, Jones, Nanette, additional, Kinsman, Crystal, additional, Krumlauf, Jennifer, additional, Lewis, Sandy, additional, Locke, Heather, additional, Margherio, Alan, additional, Markus, Debra, additional, Marsh, Tanya, additional, Neal, Serena, additional, Noffke, Amy, additional, Oh, Kean, additional, Pence, Clarence, additional, Preston, Lisa, additional, Raphaelian, Paul, additional, Regan, Virginia R., additional, Roberts, Peter, additional, Ruby, Alan, additional, Sarrafizadeh, Ramin, additional, Scherf, Marissa, additional, Scott, Sarita, additional, Sneed, Scott, additional, Staples, Lisa, additional, Terry, Brad, additional, Trese, Matthew T., additional, Videtich, Joan, additional, Williams, George, additional, Zajechowski, Mary, additional, Joseph, Daniel P., additional, Blinder, Kevin, additional, Boyd, Lynda, additional, Buckley, Sarah, additional, Crow, Meaghan, additional, Dinatale, Amanda, additional, Engelbrecht, Nicholas, additional, Forke, Bridget, additional, Gabel, Dana, additional, Grand, Gilbert, additional, Grillion-Cerone, Jennifer, additional, Holekamp, Nancy, additional, Kelly, Charlotte, additional, Nobel, Ginny, additional, Pepple, Kelly, additional, Raeber, Matt, additional, Kumar Rao, P., additional, Ressel, Tammy, additional, Schremp, Steven, additional, Sgorlon, Merrilee, additional, Shears, Shantia, additional, Thomas, Matthew, additional, Timma, Cathy, additional, Vaughn, Annette, additional, Walters, Carolyn, additional, Weeks, Rhonda, additional, Wehmeier, Jarrod, additional, Wright, Tim, additional, Berinstein, Daniel M., additional, Ayyad, Aida, additional, Barazi, Mohammed K., additional, Bickhart, Erica, additional, Brady, Tracey, additional, Byank, Lisa, additional, Cronise, Alysia, additional, Denny, Vanessa, additional, Dunn, Courtney, additional, Flory, Michael, additional, Frantz, Robert, additional, Garfinkel, Richard A., additional, Gilbert, William, additional, Lai, Michael M., additional, Melamud, Alexander, additional, Newgen, Janine, additional, Newton, Shamekia, additional, Oliver, Debbie, additional, Osman, Michael, additional, Sanders, Reginald, additional, von Fricken, Manfred, additional, Dugel, Pravin, additional, Arenas, Sandra, additional, Balea, Gabe, additional, Bartoli, Dayna, additional, Bucci, John, additional, Cornelius, Jennifer A., additional, Dickens, Scheleen, additional, Doherty, Don, additional, Dunlap, Heather, additional, Goldenberg, David, additional, Jamal, Karim, additional, Jimenez, Norma, additional, Kavanagh, Nicole, additional, Kunimoto, Derek, additional, Martin, John, additional, Miner, Jessica, additional, Mobley, Sarah, additional, Park, Donald, additional, Quinlan, Edward, additional, Sipperley, Jack, additional, Slagle, Carol, additional, Smith, Danielle, additional, Yafchak, Miguelina, additional, Yager, Rohana, additional, Flaxel, Christina J., additional, Bailey, Steven, additional, Francis, Peter, additional, Howell, Chris, additional, Hwang, Thomas, additional, Ira, Shirley, additional, Klein, Michael, additional, Lauer, Andreas, additional, Liesegang, Teresa, additional, Lundquist, Ann, additional, Nolte, Sarah, additional, Nolte, Susan K., additional, Pickell, Scott, additional, Pope, Susan, additional, Rossi, Joseph, additional, Schain, Mitchell, additional, Steinkamp, Peter, additional, Toomey, Maureen D., additional, Vahrenwald, Debora, additional, West, Kelly, additional, Hubbard, Baker, additional, Andelman, Stacey, additional, Bergstrom, Chris, additional, Brower, Judy, additional, Cribbs, Blaine, additional, Curtis, Linda, additional, Dobbs, Jannah, additional, DuBois, Lindreth, additional, Gaultney, Jessica, additional, Gibbs, Deborah, additional, Jordan, Debora, additional, Leef, Donna, additional, Martin, Daniel F., additional, Myles, Robert, additional, Olsen, Timothy, additional, Schwent, Bryan, additional, Srivastava, Sunil, additional, Waldron, Rhonda, additional, Antoszyk, Andrew N., additional, Balasubramaniam, Uma, additional, Brooks, Danielle, additional, Brown, Justin, additional, Browning, David, additional, Clark, Loraine, additional, Ennis, Sarah, additional, Held, Susannah, additional, Helms, Jennifer V., additional, Herby, Jenna, additional, Karow, Angie, additional, Leotaud, Pearl, additional, Massimino, Caterina, additional, McClain, Donna, additional, McOwen, Michael, additional, Mindel, Jennifer, additional, Pereira, Candace, additional, Pierce, Rachel, additional, Powers, Michele, additional, Price, Angela, additional, Rohrer, Jason, additional, Sanders, Jason, additional, Avery, Robert L., additional, Avery, Kelly, additional, Basefsky, Jessica, additional, Beckner, Liz, additional, Castellarin, Alessandro, additional, Couvillion, Stephen, additional, Giust, Jack, additional, Giust, Matthew, additional, Nasir, Maan, additional, Pieramici, Dante, additional, Rabena, Melvin, additional, Risard, Sarah, additional, See, Robert, additional, Smith, Jerry, additional, Wan, Lisha, additional, Bakri, Sophie J., additional, Abu-Yaghi, Nakhleh, additional, Barkmeier, Andrew, additional, Berg, Karin, additional, Burrington, Jean, additional, Edwards, Albert, additional, Goddard, Shannon, additional, Howard, Shannon, additional, Iezzi, Raymond, additional, Lewison, Denise, additional, Link, Thomas, additional, McCannel, Colin A., additional, Overend, Joan, additional, Pach, John, additional, Ruszczyk, Margaret, additional, Shultz, Ryan, additional, Stephan, Cindy, additional, Vogen, Diane, additional, Bradford, Reagan H., additional, Bergman, Vanessa, additional, Burris, Russ, additional, Butt, Amanda, additional, Daniels, Beth, additional, Dwiggins, Connie, additional, Fransen, Stephen, additional, Guerrero, Tiffany, additional, Haivala, Darin, additional, Harris, Amy, additional, Icks, Sonny, additional, Kingsley, Ronald, additional, Redden, Lena, additional, Richmond, Rob, additional, Ross, Brittany, additional, White, Kammerin, additional, Youngberg, Misty, additional, Topping, Trexler M., additional, Bennett, Steve, additional, Chong, Sandy, additional, Ciotti, Mary, additional, Cleary, Tina, additional, Corey, Emily, additional, Donovan, Dennis, additional, Frederick, Albert, additional, Freese, Lesley, additional, Graham, Margaret, additional, Gud, Natalya, additional, Howard, Taneika, additional, Jones, Mike, additional, Morley, Michael, additional, Moses, Katie, additional, Stone, Jen, additional, Ty, Robin, additional, Wiegand, Torsten, additional, Williams, Lindsey, additional, Winder, Beth, additional, Awh, Carl C., additional, Amonette, Michelle, additional, Arrindell, Everton, additional, Beck, Dena, additional, Busbee, Brandon, additional, Dilback, Amy, additional, Downs, Sara, additional, Guidry, Allison, additional, Gutow, Gary, additional, Hardin, Jackey, additional, Hines, Sarah, additional, Hutchins, Emily, additional, LaCivita, Kim, additional, Lester, Ashley, additional, Malott, Larry, additional, McCain, MaryAnn, additional, Miracle, Jayme, additional, Moffat, Kenneth, additional, Palazzotta, Lacy, additional, Robinson, Kelly, additional, Sonkin, Peter, additional, Travis, Alecia, additional, Wallace, Roy Trent, additional, Winters, Kelly J., additional, Wray, Julia, additional, Harris, April E., additional, Bunnell, Mari, additional, Crooks, Katrina, additional, Fitzgerald, Rebecca, additional, Javid, Cameron, additional, Kew, Corin, additional, Kill, Erica, additional, Kline, Patricia, additional, Kreienkamp, Janet, additional, Martinez, Maricruz, additional, Ann Moore, Roy, additional, Saavedra, Egbert, additional, Taylor, LuAnne, additional, Walsh, Mark, additional, Wilson, Larry, additional, Ciulla, Thomas A., additional, Coyle, Ellen, additional, Harrington, Tonya, additional, Harris, Charlotte, additional, Hood, Cindi, additional, Kerr, Ingrid, additional, Maturi, Raj, additional, Moore, Dawn, additional, Morrow, Stephanie, additional, Savage, Jennifer, additional, Sink, Bethany, additional, Steele, Tom, additional, Thukral, Neelam, additional, Wilburn, Janet, additional, Walker, Joseph P., additional, Banks, Jennifer, additional, Ciampaglia, Debbie, additional, Dyshanowitz, Danielle, additional, Frederick, Jennifer, additional, Tom Ghuman, A., additional, Grodin, Richard, additional, Kiesel, Cheryl, additional, Knips, Eileen, additional, McCue, Jonathan, additional, Ortiz, Maria, additional, Peters, Crystal, additional, Raskauskas, Paul, additional, Schoeman, Etienne, additional, Sharma, Ashish, additional, Wing, Glenn, additional, Youngblood, Rebecca, additional, Chandra, Suresh R., additional, Altaweel, Michael, additional, Blodi, Barbara, additional, Burke, Kathryn, additional, Dietzman, Kristine A., additional, Gottlieb, Justin, additional, Knutson, Gene, additional, Krolnik, Denise, additional, Michael Nork, T., additional, Olson, Shelly, additional, Peterson, John, additional, Reed, Sandra, additional, Soderling, Barbara, additional, Somers, Guy, additional, Stevens, Thomas, additional, Wealti, Angela, additional, Bearelly, Srilaxmi, additional, Branchaud, Brenda, additional, Bryant, Joyce W., additional, Crowell, Sara, additional, Fekrat, Sharon, additional, Gammage, Merritt, additional, Harrison, Cheala, additional, Jones, Sarah, additional, McClain, Noreen, additional, McCuen, Brooks, additional, Mruthyunjaya, Prithvi, additional, Queen, Jeanne, additional, Sarin, Neeru, additional, Skalak, Cindy, additional, Skelly, Marriner, additional, Suner, Ivan, additional, Tomany, Ronnie, additional, Welch, Lauren, additional, Park, Susanna S., additional, Cassidy, Allison, additional, Chandra, Karishma, additional, Good, Idalew, additional, Imson, Katrina, additional, Kaur, Sashi, additional, Metzler, Helen, additional, Morse, Lawrence, additional, Redenbo, Ellen, additional, Salvador, Marisa, additional, Telander, David, additional, Thomas, Mark, additional, Wallace, Cindy, additional, Barr, Charles C., additional, Battcher, Amanda, additional, Bottorff, Michelle, additional, Chasteen, Mary, additional, Clark, Kelly, additional, Denning, Diane, additional, Schoen, Debra, additional, Schultz, Amy, additional, Tempel, Evie, additional, Wheeler, Lisa, additional, Whittington, Greg K., additional, Stone, Thomas W., additional, Blevins, Todd, additional, Buck, Michelle, additional, Cruz, Lynn, additional, Heath, Wanda, additional, Holcomb, Diana, additional, Isernhagen, Rick, additional, Kidd, Terri, additional, Kitchens, John, additional, Sears, Cathy, additional, Slade, Ed, additional, Van Arsdall, Jeanne, additional, VanHoose, Brenda, additional, Wolfe, Jenny, additional, Wood, William, additional, Zilis, John, additional, Crooks, Carol, additional, Disney, Larry, additional, Liu, Mimi, additional, Petty, Stephen, additional, Sall, Sandra, additional, Folk, James C., additional, Aly, Tracy, additional, Brotherton, Abby, additional, Critser, Douglas, additional, Hinz, Connie J., additional, Karakas, Stefani, additional, Kirschner, Valerie, additional, Lester, Cheyanne, additional, Montague, Cindy, additional, Russell, Stephen, additional, Stockman, Heather, additional, Taylor, Barbara, additional, Verdick, Randy, additional, Walshire, Jean, additional, Thompson, John T., additional, Connell, Barbara, additional, Constantine, Maryanth, additional, Davis, John L., additional, Holsapple, Gwen, additional, Hunter, Lisa, additional, Lenane, C. Nicki, additional, Mitchell, Robin, additional, Russel, Leslie, additional, Sjaarda, Raymond, additional, Brown, David M., additional, Benz, Matthew, additional, Burns, Llewellyn, additional, Carranza, JoLene G., additional, Fish, Richard, additional, Goates, Debra, additional, Hay, Shayla, additional, Jeffers, Theresa, additional, Kegley, Eric, additional, Kubecka, Dallas, additional, McGilvra, Stacy, additional, Richter, Beau, additional, Sneed, Veronica, additional, Stoever, Cary, additional, Tellez, Isabell, additional, Wong, Tien, additional, Kim, Ivana, additional, Andreoli, Christopher, additional, Barresi, Leslie, additional, Brett, Sarah, additional, Callahan, Charlene, additional, Capaccioli, Karen, additional, Carli, William, additional, Coppola, Matthew, additional, Emmanuel, Nicholas, additional, Evans, Claudia, additional, Fagan, Anna, additional, Grillo, Marcia, additional, Head, John, additional, Kieser, Troy, additional, Lee, Elaine, additional, Lord, Ursula, additional, Miretsky, Edward, additional, Palitsch, Kate, additional, Petrin, Todd, additional, Reader, Liz, additional, Reznichenko, Svetlana, additional, Robertson, Mary, additional, Smith, Justin, additional, Vavvas, Demetrios, additional, Wells, John, additional, Cahill, Cassie, additional, Lloyd Clark, W., additional, Henry, Kayla, additional, Johnson, David, additional, Miller, Peggy, additional, Oliver, LaDetrick, additional, Spivey, Robbin, additional, Swinford, Tiffany, additional, Taylor, Mallie, additional, Lambert, Michael, additional, Chase, Kris, additional, Fredrickson, Debbie, additional, Khawly, Joseph, additional, Lazarte, Valerie, additional, Lowd, Donald, additional, Miller, Pam, additional, Willis, Arthur, additional, Ferrone, Philip J., additional, Almonte, Miguel, additional, Arnott, Rachel, additional, Aviles, Ingrid, additional, Carbon, Sheri, additional, Chitjian, Michael, additional, DAmore, Kristen, additional, Elliott, Christin, additional, Fastenberg, David, additional, Golub, Barry, additional, Graham, Kenneth, additional, Lavorna, AnnMarie, additional, Murphy, Laura, additional, Palomo, Amanda, additional, Puglisi, Christina, additional, Rhee, David, additional, Romero, Juan, additional, Rosenblatt, Brett, additional, Salcedo, Glenda, additional, Schlameuss, Marianne, additional, Shakin, Eric, additional, Sookhai, Vasanti, additional, Kaiser, Richard, additional, Affel, Elizabeth, additional, Brown, Gary, additional, Centinaro, Christina, additional, Fine, Deborah, additional, Fineman, Mitchell, additional, Formoso, Michele, additional, Garg, Sunir, additional, Grande, Lisa, additional, Herbert, Carolyn, additional, Ho, Allen, additional, Hsu, Jason, additional, Jay, Maryann, additional, Lavetsky, Lisa, additional, Liebenbaum, Elaine, additional, Maguire, Joseph, additional, Monsonego, Julia, additional, O'Connor, Lucia, additional, Pierce, Lisa, additional, Regillo, Carl, additional, Rosario, Maria, additional, Spirn, Marc, additional, Vander, James, additional, Walsh, Jennifer, additional, Davidorf, Frederick H., additional, Barnett, Amanda, additional, Chang, Susie, additional, Christoforidis, John, additional, Elliott, Joy, additional, Justice, Heather, additional, Letson, Alan, additional, McKinney, Kathryne, additional, Perry, Jeri, additional, Salerno, Jill A., additional, Savage, Scott, additional, Shelley, Stephen, additional, Singerman, Lawrence J., additional, Coney, Joseph, additional, DuBois, John, additional, DuBois, Kimberly, additional, Greanoff, Gregg, additional, Himmelman, Dianne, additional, Ilc, Mary, additional, Mcnamara, Elizabeth, additional, Novak, Michael, additional, Pendergast, Scott, additional, Rath, Susan, additional, Smith-Brewer, Sheila, additional, Tanner, Vivian, additional, Weiss, Diane E., additional, Zegarra, Hernando, additional, Halperin, Lawrence, additional, Aramayo, Patricia, additional, Dhalla, Mandeep, additional, Fernandez, Brian, additional, Fernandez, Cindy, additional, Lopez, Jaclyn, additional, Lopez, Monica, additional, Mariano, Jamie, additional, Murphy, Kellie, additional, Sherley, Clifford, additional, Veksler, Rita, additional, Rahhal, Firas, additional, Babikian, Razmig, additional, Boyer, David, additional, Hami, Sepideh, additional, Kessinger, Jeff, additional, Kurokouchi, Janet, additional, Mukarram, Saba, additional, Pachman, Sarah, additional, Protacio, Eric, additional, Sierra, Julio, additional, Tabandeh, Homayoun, additional, Zamboni, Adam, additional, Elman, Michael, additional, Belz, Jennifer, additional, Butcher, Tammy, additional, Cain, Theresa, additional, Coffey, Teresa, additional, Firestone, Dena, additional, Gore, Nancy, additional, Singletary, Pamela, additional, Sotirakos, Peter, additional, Starr, JoAnn, additional, Meredith, Travis A., additional, Barnhart, Cassandra J., additional, Cantrell, Debra, additional, Esquejo-Leon, RonaLyn, additional, Houghton, Odette, additional, Kaur, Harpreet, additional, NDure, Fatoumatta, additional, Glatzer, Ronald, additional, Joffe, Leonard, additional, Schindler, Reid, additional, Fine, Stuart L., additional, Katz, Marilyn, additional, Brightwell-Arnold, Mary, additional, Glaser, Ruchira, additional, Hall, Judith, additional, Harkins, Sandra, additional, Huang, Jiayan, additional, Khvatov, Alexander, additional, McWilliams, Kathy, additional, Peskin, Ellen, additional, Pistilli, Maxwell, additional, Ryan, Susan, additional, Schnader, Allison, additional, Ying, Gui-Shuang, additional, Jaffe, Glenn, additional, Afrani-Sakyi, Jennifer, additional, Balsley, Brannon, additional, Bennett, Linda S., additional, Brooks, Adam, additional, Brower-Lingsch, Adrienne, additional, Bruce, Lori, additional, Burns, Russell, additional, Busian, Dee, additional, Choong, John, additional, Cloaninger, Lindsey, additional, DeCroos, Francis Char, additional, DuBois, Emily, additional, El-Dairi, Mays, additional, Gach, Sarah, additional, Hall, Katelyn, additional, Hawks, Terry, additional, Huang, ChengChenh, additional, Heydary, Cindy, additional, Ho, Alexander, additional, Kini, Shashi, additional, McCall, Michelle, additional, Muhammad, Daaimah, additional, Nicholson, Jayne, additional, Rieves, Pamela, additional, Shields, Kelly, additional, Specker, Adam, additional, Stinnett, Sandra, additional, Subramaniam, Sujatha, additional, Tenbrink, Patrick, additional, Toth, Cynthia, additional, Towe, Aaron, additional, Welch, Kimberly, additional, Williams, Natasha, additional, Winter, Katrina, additional, Young, Ellen, additional, Alexander, Judith, additional, Flannagan, Elisabeth, additional, Martin, E. Revell, additional, Parker, Candace, additional, Sepielli, Krista, additional, Shannon, Tom, additional, Whearry, Claressa, additional, Redford, Maryann, additional, Kopfer, Marcia R., additional, Ferris, Frederick L., additional, DuPont, Joan, additional, Friedman, Lawrence M., additional, Bressler, Susan B., additional, DeMets, David L., additional, Friedlander, Martin, additional, Johnson, Mark W., additional, Lindblad, Anne, additional, Losordo, Douglas W., additional, and Miller, Franklin G., additional

Published
2015
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41. Therapeutic identification of depression in young people: lessons from the introduction of a new technique in general practice.

Author

Iliffe S, Gallant C, Kramer T, Gledhill J, Bye A, Fernandez V, Vila M, Miller L, Garralda ME, Iliffe, Steve, Gallant, Ceri, Kramer, Tami, Gledhill, Julia, Bye, Amanda, Fernandez, Victoria, Vila, Mar, Miller, Lisa, and Garralda, M Elena

Abstract

Background: Mild-to-moderate depression in young people is associated with impaired social functioning and high rates of affective disorder in adult life. Earlier recognition of depression in young people has the potential to reduce the burden of depression in adulthood. However, depression in teenagers is underdiagnosed and undertreated.Aim: To assess the usability and usefulness of a cognitive-behavioural-therapy-based technique for Therapeutic Identification of Depression in Young people (TIDY).Design and Setting: A qualitative study of four group practices in northwest London.Method: Face-to-face semi-structured interviews were conducted with practitioners who had been trained in the use of the TIDY technique.Results: Twenty-five GPs and six nurses were interviewed. The key themes that emerged from the interviews were: practitioners were 'making sense of teenage depression' when interpreting signs and symptoms; the training in the technique was variable in its impact on practitioners' attitudes and practice; and time factors constrained practitioners in the application of the technique.Conclusion: The TIDY technique is usable in routine practice, but only if practitioners are allowed to use it selectively. This need for selectivity arises partly from concerns about time management, and partly to avoid medicalisation of psychological distress in young people. The perceived usefulness of the TIDY technique depends on the practitioner's prior knowledge, experience, and awareness. [ABSTRACT FROM AUTHOR]

Published
2012
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42. Predominantly Persistent Intraretinal Fluid in the Comparison of Age-related Macular Degeneration Treatments Trials

Author

Core, Jason Q., Pistilli, Maxwell, Hua, Peiying, Daniel, Ebenezer, Grunwald, Juan E., Toth, Cynthia A., Jaffe, Glenn J., Martin, Daniel F., Maguire, Maureen G., Ying, Gui-Shuang, Williams, David F., Beardsley, Sara, Bennett, Steven, Cantrill, Herbert, Chan-Tram, Carmen, Cheshier, Holly, Davies, John, Dev, Sundeep, Enloe, Julianne, Follano, Gennaro, Gilbert, Peggy, Johnson, Jill, Jones, Tori, Mayleben, Lisa, Mittra, Robert, Moos, Martha, Neist, Ryan, Oestreich, Neal, Quiram, Polly, Ramsay, Robert, Ryan, Edwin, Schindeldecker, Stephanie, Steele, Trenise, Tonsfeldt, Jessica, Valardi, Shelly, Fish, Gary Edd, Aguado, Hank A., Arceneaux, Sally, Arnwine, Jean, Bell, Kim, Bell, Tina, Boleman, Bob, Bradley, Patricia, Callanan, David, Coors, Lori, Creighton, Jodi, Cummings, Kimberly, Dock, Christopher, Duignan, Karen, Fuller, Dwain, Gray, Keith, Hendrix, Betsy, Hesse, Nicholas, Jaramillo, Diana, Jost, Bradley, Lash, Sandy, Lonsdale, Laura, Mackens, Michael, Mutz, Karin, Potts, Michael, Sanchez, Brenda, Snyder, William, Solley, Wayne, Tarter, Carrie, Wang, Robert, Williams, Patrick, Perkins, Stephen L., Anderson, Nicholas, Arnold, Ann, Blais, Paul, Googe, Joseph, Higdon, Tina T., Hunt, Cecile, Johnson, Mary, Miller, James, Moore, Misty, Morris, Charity K., Morris, Christopher, Oelrich, Sarah, Oliver, Kristina, Seitz, Vicky, Whetstone, Jerry, Doft, Bernard H., Bedel, Jay, Bergren, Robert, Borthwick, Ann, Conrad, Paul, Fulwylie, Christina, Ingram, Willia, Latham, Shawnique, Lester, Gina, Liu, Judy, Lobes, Louis, Lucko, Nicole M., Merlotti, Lori, Olsen, Karl, Puskas, Danielle, Rath, Pamela, Schueckler, Lynn, Schultz, Christina, Shultz, Heather, Steinberg, David, Vyas, Avni, Whale, Kim, Yeckel, Kimberly, Orth, David H., Arredondo, Linda S., Brown, Susan, Ciscato, Barbara J., Civantos, Joseph M., Figliulo, Celeste, Hasan, Sohail, Kosinski, Belinda, Muir, Dan, Nelson, Kiersten, Packo, Kirk, Pollack, John S., Rezaei, Kourous, Shelton, Gina, Townsend-Patrick, Shannya, Walsh, Marian, Richard McDonald, H., Ansari, Nina, Bye, Amanda, Fu, Arthur D., Grout, Sean, Indermill, Chad, Johnson, Robert N., Jumper, J. Michael, Linares, Silvia, Lujan, Brandon J., Munden, Ames, Rodriguez, Rosa, Rose, Jennifer M., Teske, Brandi, Urias, Yesmin, Young, Stephen, Dreyer, Richard F., Daniel, Howard, Connaughton, Michele, Handelman, Irvin, Hobbs, Stephen, Hoerner, Christine, Hudson, Dawn, Kopfer, Marcia, Lee, Michael, Lemley, Craig, Logan, Joe, Ma, Colin, Mallet, Christophe, Milliron, Amanda, Peters, Mark, Wohlsein, Harry, Pearlman, Joel A., Andrews, Margo, Bartlett, Melissa, Carlson, Nanette, Cox, Emily, Equi, Robert, Gonzalez, Marta, Griffin, Sophia, Hogue, Fran, Kennedy, Lance, Kryuchkov, Lana, Lopez, Carmen, Lopez, Danny, Luevano, Bertha, McKenna, Erin, Patel, Arun, Reed, Brian, Secor, Nyla, Sison, Iris R., Tsai, Tony, Varghis, Nina, Waller, Brooke, Wendel, Robert, Yebra, Reina, Roth, Daniel B., Deinzer, Jane, Fine, Howard, Green, Flory, Green, Stuart, Keyser, Bruce, Leff, Steven, Leviton, Amy, Martir, Amy, Mosenthine, Kristin, Muscle, Starr, Okoren, Linda, Parker, Sandy, Prenner, Jonathan, Price, Nancy, Rogers, Deana, Rosas, Linda, Schlosser, Alex, Studenko, Loretta, Tantum, Thea, Wheatley, Harold, Trese, Michael T., Aaberg, Thomas, Bezaire, Denis, Bridges, Craig, Bryant, Doug, Capone, Antonio, Coleman, Michelle, Consolo, Christina, Cook, Cindy, DuLong, Candice, Garretson, Bruce, Grooten, Tracy, Hammersley, Julie, Hassan, Tarek, Jessick, Heather, Jones, Nanette, Kinsman, Crystal, Krumlauf, Jennifer, Lewis, Sandy, Locke, Heather, Margherio, Alan, Markus, Debra, Marsh, Tanya, Neal, Serena, Noffke, Amy, Oh, Kean, Pence, Clarence, Preston, Lisa, Raphaelian, Paul, Regan, Virginia R., Roberts, Peter, Ruby, Alan, Sarrafizadeh, Ramin, Scherf, Marissa, Scott, Sarita, Sneed, Scott, Staples, Lisa, Terry, Brad, Trese, Matthew T., Videtich, Joan, Williams, George, Zajechowski, Mary, Joseph, Daniel P., Blinder, Kevin, Boyd, Lynda, Buckley, Sarah, Crow, Meaghan, Dinatale, Amanda, Engelbrecht, Nicholas, Forke, Bridget, Gabel, Dana, Grand, Gilbert, Grillion-Cerone, Jennifer, Holekamp, Nancy, Kelly, Charlotte, Nobel, Ginny, Pepple, Kelly, Raeber, Matt, Rao, P. Kumar, Ressel, Tammy, Schremp, Steven, Sgorlon, Merrilee, Shears, Shantia, Thomas, Matthew, Timma, Cathy, Vaughn, Annette, Walters, Carolyn, Weeks, Rhonda, Wehmeier, Jarrod, Wright, Tim, Berinstein, Daniel M., Ayyad, Aida, Barazi, Mohammed K., Bickhart, Erica, Byank, Lisa, Cronise, Alysia, Denny, Vanessa, Dunn, Courtney, Flory, Michael, Frantz, Robert, Garfinkel, Richard A., Gilbert, William, Lai, Michael M., Melamud, Alexander, Newgen, Janine, Newton, Shamekia, Oliver, Debbie, Osman, Michael, Sanders, Reginald, von Fricken, Manfred, Dugel, Pravin, Arenas, Sandra, Balea, Gabe, Bartoli, Dayna, Bucci, John, Cornelius, Jennifer A., Dickens, Scheleen, Doherty, Don, Dunlap, Heather, Goldenberg, David, Jamal, Karim, Jimenez, Norma, Kavanagh, Nicole, Kunimoto, Derek, Martin, John, Miner, Jessica, Mobley, Sarah, Park, Donald, Quinlan, Edward, Sipperley, Jack, Slagle, Carol, Smith, Danielle, Yager, Rohana, Flaxel, Christina J., Bailey, Steven, Francis, Peter, Howell, Chris, Hwang, Thomas, Ira, Shirley, Klein, Michael, Lauer, Andreas, Liesegang, Teresa, Lundquist, Ann, Nolte, Sarah, Nolte, Susan K., Pickell, Scott, Pope, Susan, Rossi, Joseph, Schain, Mitchell, Steinkamp, Peter, Toomey, Maureen D., Vahrenwald, Debora, West, Kelly, Hubbard, Baker, Andelman, Stacey, Bergstrom, Chris, Brower, Judy, Cribbs, Blaine, Curtis, Linda, Dobbs, Jannah, DuBois, Lindreth, Gaultney, Jessica, Gibbs, Deborah, Jordan, Debora, Leef, Donna, Martin, Daniel F., Myles, Robert, Olsen, Timothy, Schwent, Bryan, Srivastava, Sunil, Waldron, Rhonda, Antoszyk, Andrew N., Balasubramaniam, Uma, Brooks, Danielle, Brown, Justin, Browning, David, Clark, Loraine, Ennis, Sarah, Helms, Jennifer V., Herby, Jenna, Karow, Angie, Leotaud, Pearl, Massimino, Caterina, McClain, Donna, McOwen, Michael, Mindel, Jennifer, Pereira, Candace, Pierce, Rachel, Powers, Michele, Price, Angela, Rohrer, Jason, Sanders, Jason, Avery, Robert L., Avery, Kelly, Basefsky, Jessica, Beckner, Liz, Castellarin, Alessandro, Couvillion, Stephen, Giust, Jack, Giust, Matthew, Nasir, Maan, Pieramici, Dante, Rabena, Melvin, Risard, Sarah, See, Robert, Smith, Jerry, Bakri, Sophie J., Abu-Yaghi, Nakhleh, Barkmeier, Andrew, Berg, Karin, Burrington, Jean, Edwards, Albert, Goddard, Shannon, Howard, Shannon, Iezzi, Raymond, Lewison, Denise, Link, Thomas, McCannel, Colin A., Overend, Joan, Pach, John, Ruszczyk, Margaret, Shultz, Ryan, Stephan, Cindy, Vogen, Diane, Bradford, Reagan H., Bergman, Vanessa, Burris, Russ, Butt, Amanda, Daniels, Beth, Dwiggins, Connie, Fransen, Stephen, Guerrero, Tiffany, Haivala, Darin, Harris, Amy, Icks, Sonny, Kingsley, Ronald, Richmond, Rob, Ross, Brittany, White, Kammerin, Youngberg, Misty, Topping, Trexler M., Bennett, Steve, Chong, Sandy, Cleary, Tina, Corey, Emily, Donovan, Dennis, Frederick, Albert, Freese, Lesley, Graham, Margaret, Gud, Natalya, Howard, Taneika, Jones, Mike, Morley, Michael, Moses, Katie, Stone, Jen, Ty, Robin, Wiegand, Torsten, Williams, Lindsey, Winder, Beth, Awh, Carl C., Arrindell, Everton, Beck, Dena, Busbee, Brandon, Dilback, Amy, Downs, Sara, Guidry, Allison, Gutow, Gary, Hardin, Jackey, Hines, Sarah, Hutchins, Emily, LaCivita, Kim, Lester, Ashley, Malott, Larry, McCain, MaryAnn, Miracle, Jayme, Moffat, Kenneth, Palazzotta, Lacy, Robinson, Kelly, Sonkin, Peter, Travis, Alecia, Wallace, RoyTrent, Winters, Kelly J., Wray, Julia, Harris, April E., Bunnell, Mari, Crooks, Katrina, Fitzgerald, Rebecca, Javid, Cameron, Kew, Corin, Kill, Erica, Kline, Patricia, Kreienkamp, Janet, Moore, RoyAnn, Saavedra, Egbert, Taylor, LuAnne, Walsh, Mark, Wilson, Larry, Ciulla, Thomas A., Coyle, Ellen, Harrington, Tonya, Harris, Charlotte, Maturi, Raj, Morrow, Stephanie, Savage, Jennifer, Sink, Bethany, Steele, Tom, Thukral, Neelam, Wilburn, Janet, Walker, Joseph P., Banks, Jennifer, Dyshanowitz, Debbie, Ciampaglia, Danielle, Frederick, Jennifer, Tom Ghuman, A., Grodin, Richard, Kiesel, Cheryl, Knips, Eileen, Peters, Crystal, Raskauskas, Paul, Schoeman, Etienne, Sharma, Ashish, Wing, Glenn, Chandra, Suresh R., Altaweel, Michael, Blodi, Barbara, Burke, Kathryn, Dietzman, Kristine A., Gottlieb, Justin, Knutson, Gene, Krolnik, Denise, Michael Nork, T., Olson, Shelly, Peterson, John, Reed, Sandra, Soderling, Barbara, Somers, Guy, Stevens, Thomas, Wealti, Angela, Bearelly, Srilaxmi, Branchaud, Brenda, Bryant, Joyce W., Crowell, Sara, Fekrat, Sharon, Gammage, Merritt, Harrison, Cheala, Jones, Sarah, McClain, Noreen, McCuen, Brooks, Mruthyunjaya, Prithvi, Queen, Jeanne, Sarin, Neeru, Skalak, Cindy, Skelly, Marriner, Suner, Ivan, Tomany, Ronnie, Welch, Lauren, Park, Susanna S., Cassidy, Allison, Chandra, Karishma, Good, Idalew, Imson, Katrina, Kaur, Sashi, Metzler, Helen, Morse, Lawrence, Redenbo, Ellen, Salvador, Marisa, Telander, David, Thomas, Mark, Wallace, Cindy, Barr, Charles C., Battcher, Amanda, Bottorff, Michelle, Chasteen, Mary, Clark, Kelly, Denning, Diane, Schultz, Amy, Tempel, Evie, Whittington, Greg K., Stone, Thomas W., Blevins, Todd, Buck, Michelle, Cruz, Lynn, Heath, Wanda, Holcomb, Diana, Isernhagen, Rick, Kidd, Terri, Kitchens, John, Sears, Cathy, Slade, Ed, Van Arsdall, Jeanne, VanHoose, Brenda, Wolfe, Jenny, Wood, William, Zilis, John, Crooks, Carol, Disney, Larry, Liu, Mimi, Petty, Stephen, Sall, Sandra, Folk, James C., Aly, Tracy, Brotherton, Abby, Critser, Douglas, Hinz, Connie J., Karakas, Stefani, Lester, Cheyanne, Montague, Cindy, Russell, Stephen, Stockman, Heather, Taylor, Barbara, Verdick, Randy, Thompson, John T., Connell, Barbara, Constantine, Maryanth, Davis, John L., Holsapple, Gwen, Hunter, Lisa, Nicki Lenane, C., Mitchell, Robin, Russel, Leslie, Sjaarda, Raymond, Brown, David M., Benz, Matthew, Burns, Llewellyn, Carranza, JoLene G., Fish, Richard, Goates, Debra, Hay, Shayla, Jeffers, Theresa, Kegley, Eric, Kubecka, Dallas, McGilvra, Stacy, Richter, Beau, Sneed, Veronica, Stoever, Cary, Tellez, Isabell, Wong, Tien, Kim, Ivana, Andreoli, Christopher, Barresi, Leslie, Brett, Sarah, Callahan, Charlene, Capaccioli, Karen, Carli, William, Coppola, Matthew, Emmanuel, Nicholas, Evans, Claudia, Fagan, Anna, Grillo, Marcia, Head, John, Kieser, Troy, Lord, Ursula, Miretsky, Edward, Palitsch, Kate, Petrin, Todd, Reader, Liz, Reznichenko, Svetlana, Robertson, Mary, Vavvas, Demetrios, Wells, John, Cahill, Cassie, Lloyd Clark, W., Henry, Kayla, Johnson, David, Miller, Peggy, Oliver, LaDetrick, Spivey, Robbin, Taylor, Mallie, Lambert, Michael, Chase, Kris, Fredrickson, Debbie, Khawly, Joseph, Lazarte, Valerie, Lowd, Donald, Miller, Pam, Willis, Arthur, Ferrone, Philip J., Almonte, Miguel, Arnott, Rachel, Aviles, Ingrid, Carbon, Sheri, Chitjian, Michael, DAmore, Kristen, Elliott, Christin, Fastenberg, David, Golub, Barry, Graham, Kenneth, Lavorna, AnnMarie, Murphy, Laura, Palomo, Amanda, Puglisi, Christina, Rhee, David, Romero, Juan, Rosenblatt, Brett, Salcedo, Glenda, Schlameuss, Marianne, Shakin, Eric, Sookhai, Vasanti, Kaiser, Richard, Affel, Elizabeth, Brown, Gary, Centinaro, Christina, Fine, Deborah, Fineman, Mitchell, Formoso, Michele, Garg, Sunir, Grande, Lisa, Herbert, Carolyn, Ho, Allen, Hsu, Jason, Jay, Maryann, Lavetsky, Lisa, Liebenbaum, Elaine, Maguire, Joseph, Monsonego, Julia, O’Connor, Lucia, Regillo, Carl, Rosario, Maria, Spirn, Marc, Vander, James, Walsh, Jennifer, Davidorf, Frederick H., Barnett, Amanda, Chang, Susie, Christoforidis, John, Elliott, Joy, Justice, Heather, Letson, Alan, McKinney, Kathryne, Perry, Jeri, Salerno, Jill A., Savage, Scott, Shelley, Stephen, Singerman, Lawrence J., Coney, Joseph, DuBois, John, DuBois, Kimberly, Greanoff, Gregg, Himmelman, Dianne, Ilc, Mary, Mcnamara, Elizabeth, Novak, Michael, Pendergast, Scott, Rath, Susan, SmithBrewer, Sheila, Tanner, Vivian, Weiss, Diane E., Zegarra, Hernando, Halperin, Lawrence, Aramayo, Patricia, Dhalla, Mandeep, Fernandez, Brian, Fernandez, Cindy, Lopez, Jaclyn, Lopez, Monica, Mariano, Jamie, Murphy, Kellie, Sherley, Clifford, Veksler, Rita, Rahhal, Firas, Babikian, Razmig, Boyer, David, Hami, Sepideh, Kessinger, Jeff, Kurokouchi, Janet, Mukarram, Saba, Pachman, Sarah, Protacio, Eric, Sierra, Julio, Tabandeh, Homayoun, Zamboni, Adam, Elman, Michael, Butcher, Tammy, Cain, Theresa, Coffey, Teresa, Firestone, Dena, Gore, Nancy, Singletary, Pamela, Sotirakos, Peter, Starr, JoAnn, Meredith, Travis A., Barnhart, Cassandra J., Cantrell, Debra, EsquejoLeon, RonaLyn, Houghton, Odette, Kaur, Harpreet, NDure, Fatoumatta, Glatzer, Ronald, Joffe, Leonard, Schindler, Reid, Martin, Daniel F., Fine, Stuart L., Katz, Marilyn, Maguire, Maureen G., Brightwell-Arnold, Mary, Glaser, Ruchira, Hall, Judith, Harkins, Sandra, Huang, Jiayan, Khvatov, Alexander, McWilliams, Kathy, Nolte, Susan K., Peskin, Ellen, Pistilli, Maxwell, Ryan, Susan, Schnader, Allison, Ying, Gui-shuang, Jaffe, Glenn, Afrani-Sakyi, Jennifer, Balsley, Brannon, Bennett, Linda S., Brooks, Adam, Brower-Lingsch, Adrienne, Bruce, Lori, Burns, Russell, Busian, Dee, Choong, John, Cloaninger, Lindsey, Char DeCroos, Francis, DuBois, Emily, El-Dairi, Mays, Gach, Sarah, Hall, Katelyn, Hawks, Terry, Huang, ChengChenh, Heydary, Cindy, Ho, Alexander, Kini, Shashi, McCall, Michelle, Muhammad, Daaimah, Nicholson, Jayne, Queen, Jeanne, Rieves, Pamela, Shields, Kelly, Skalak, Cindy, Specker, Adam, Stinnett, Sandra, Subramaniam, Sujatha, Tenbrink, Patrick, Toth, Cynthia, Towe, Aaron, Welch, Kimberly, Williams, Natasha, Winter, Katrina, Young, Ellen, Grunwald, Juan E., Alexander, Judith, Daniel, Ebenezer, Flannagan, Elisabeth, Revell Martin, E., Parker, Candace, Sepielli, Krista, Shannon, Whearry, Claressa, Martin, Daniel F., Avery, Robert L., Bakri, Sophie J., Daniel, Ebenezer, Fine, Stuart L., Grunwald, Juan E., Jaffe, Glenn, Kopfer, Marcia R., Maguire, Maureen G., Meredith, Travis A., Peskin, Ellen, Redford, Maryann, Williams, David F., Martin, Daniel F., Bennett, Linda S., Daniel, Ebenezer, Ferris, Frederick L., Fine, Stuart L., Grunwald, Juan E., Jaffe, Glenn, Maguire, Maureen G., Peskin, Ellen, Redford, Maryann, Toth, Cynthia, Peskin, Ellen, Brightwell-Arnold, Mary, DuPont, Joan, Maguire, Maureen G., McWilliams, Kathy, Nolte, Susan K., Friedman, Lawrence M., Bressler, Susan B., DeMets, David L., Friedlander, Martin, Johnson, Mark W., Lindblad, Anne, Losordo, Douglas W., and Miller, Franklin G.

Abstract

To describe predominantly persistent intraretinal fluid (PP-IRF) and its association with visual acuity (VA) and retinal anatomic findings at long-term follow-up in eyes treated with pro re nata (PRN) ranibizumab or bevacizumab for neovascular age-related macular degeneration.

Published
2022
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43. Perinatal mental health services in pregnancy and the year after birth: the ESMI research programme including RCT

Author

Howard LM, Abel KM, Atmore KH, Bick D, Bye A, Byford S, Carson LE, Dolman C, Heslin M, Hunter M, Jennings S, Johnson S, Jones I, Taylor BL, McDonald R, Milgrom J, Morant N, Nath S, Pawlby S, Potts L, Powell C, Rose D, Ryan E, Seneviratne G, Shallcross R, Stanley N, Trevillion K, Wieck A, and Pickles A

Abstract

Background: It is unclear how best to identify and treat women with mental disorders in pregnancy and the year after birth (i.e. the perinatal period)., Objectives: (1) To investigate how best to identify depression at antenatal booking [work package (WP) 1]. (2) To estimate the prevalence of mental disorders in early pregnancy (WP1). (3) To develop and examine the efficacy of a guided self-help intervention for mild to moderate antenatal depression delivered by psychological well-being practitioners (WP1). (4) To examine the psychometric properties of the perinatal VOICE (Views On Inpatient CarE) measure of service satisfaction (WP3). (5) To examine the clinical effectiveness and cost-effectiveness of services for women with acute severe postnatal mental disorders (WPs 1–3). (6) To investigate women’s and partners’/significant others’ experiences of different types of care (WP2)., Design: Objectives 1 and 2 – a cross-sectional survey stratified by response to Whooley depression screening questions. Objective 3 – an exploratory randomised controlled trial. Objective 4 – an exploratory factor analysis, including test–retest reliability and validity assessed by association with the Client Satisfaction Questionnaire contemporaneous satisfaction scores. Objective 5 – an observational cohort study using propensity scores for the main analysis and instrumental variable analysis using geographical distance to mother and baby unit. Objective 6 – a qualitative study., Setting: English maternity services and generic and specialist mental health services for pregnant and postnatal women., Participants: Staff and users of mental health and maternity services., Interventions: Guided self-help, mother and baby units and generic care., Main Outcome Measures: The following measures were evaluated in WP1(i) – specificity, sensitivity, positive predictive value, likelihood ratio, acceptability and population prevalence estimates. The following measures were evaluated in WP1(ii) – participant recruitment rate, attrition and adverse events. The following measure was evaluated in WP2 – experiences of care. The following measures were evaluated in WP3 – psychometric indices for perinatal VOICE and the proportion of participants readmitted to acute care in the year after discharge., Results: WP1(i) – the population prevalence estimate was 11% (95% confidence interval 8% to 14%) for depression and 27% (95% confidence interval 22% to 32%) for any mental disorder in early pregnancy. The diagnostic accuracy of two depression screening questions was as follows: a weighted sensitivity of 0.41, a specificity of 0.95, a positive predictive value of 0.45, a negative predictive value of 0.93 and a likelihood ratio (positive) of 8.2. For the Edinburgh Postnatal Depression Scale, the diagnostic accuracy was as follows: a weighted sensitivity of 0.59, a specificity of 0.94, a positive predictive value of 0.52, a negative predictive value of 0.95 and a likelihood ratio (positive) of 9.8. Most women reported that asking about depression at the antenatal booking appointment was acceptable, although this was reported as being less acceptable for women with mental disorders and/or experiences of abuse. Cost-effectiveness analysis suggested that both the Whooley depression screening questions and the Edinburgh Postnatal Depression Scale were more cost-effective than with the Whooley depression screening questions followed by the Edinburgh Postnatal Depression Scale or no-screen option. WP1(ii) – 53 women with depression in pregnancy were randomised. Twenty-six women received modified guided self-help [with 18 (69%) women attending four or more sessions] and 27 women received usual care. Three women were lost to follow-up (follow-up for primary outcome: 92%). At 14 weeks post randomisation, women receiving guided self-help reported fewer depressive symptoms than women receiving usual care (adjusted effect size −0.64, 95% confidence interval −1.30 to 0.06). Costs and quality-adjusted life-years were similar, resulting in a 50% probability of guided self-help being cost-effective compared with usual care at National Institute for Health and Care Excellence cost per quality-adjusted life-year thresholds. The slow recruitment rate means that a future definitive larger trial is not feasible. WP2 – qualitative findings indicate that women valued clinicians with specialist perinatal expertise across all services, but for some women generic services were able to provide better continuity of care. Involvement of family members and care post discharge from acute services were perceived as poor across services, but there was also ambivalence among some women about increasing family involvement because of a complex range of factors. WP3(i) – for the perinatal VOICE, measures from exploratory factor analysis suggested that two factors gave an adequate fit (comparative fit index = 0.97). Items loading on these two dimensions were (1) those concerning aspects of the service relating to the care of the mother and (2) those relating to care of the baby. The factors were positively correlated (0.49; p  < 0.0001). Total scores were strongly associated with service (with higher satisfaction for mother and baby units, 2 degrees of freedom; p  < 0.0001) and with the ‘gold standard’ Client Service Questionnaire total score (test–retest intraclass correlation coefficient 0.784, 95% confidence interval 0.643 to 0.924; p  < 0.0001). WP3(ii) – 263 of 279 women could be included in the primary analysis, which shows that the odds of being readmitted to acute care was 0.95 times higher for women who were admitted to a mother and baby unit than for those not admitted to a mother and baby unit (0.95, 95% confidence interval 0.86 to 1.04; p  = 0.29). Sensitivity analysis using an instrumental variable found a markedly more significant effect of admission to mother and baby units ( p  < 0.001) than the primary analysis. Mother and baby units were not found to be cost-effective at 1 month post discharge because of the costs of care in a mother and baby unit. Cost-effectiveness advantages may exist if the cost of mother and baby units is offset by savings from reduced readmissions in the longer term., Limitations: Policy and service changes had an impact on recruitment. In observational studies, residual confounding is likely., Conclusions: Services adapted for the perinatal period are highly valued by women and may be more effective than generic services. Mother and baby units have a low probability of being cost-effective in the short term, although this may vary in the longer term., Future Work: Future work should include examination of how to reduce relapses, including in after-care following discharge, and how better to involve family members., Trial Registration: This trial is registered as ISRCTN83768230 and as study registration UKCRN ID 16403., Funding: This project was funded by the National Institute for Health and Care Research (NIHR) Programme Grants for Applied Research programme and will be published in full in Programme Grants for Applied Research ; Vol. 10, No. 5. See the NIHR Journals Library website for further project information., (Copyright © 2022 Howard et al. This work was produced by Howard et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaption in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/. For attribution the title, original author(s), the publication source – NIHR Journals Library, and the DOI of the publication must be cited.)

Published
2022
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