207 results on '"Buysschaert, Ian"'
Search Results
2. Low-dose colchicine for the prevention of cardiovascular events after percutaneous coronary intervention: Rationale and design of the COL BE PCI trial
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De Cock, Emmanuel, Kautbally, Shakeel, Timmermans, Frank, Bogaerts, Kris, Hanet, Claude, Desmet, Walter, Gurné, Olivier, Vranckx, Pascal, Hiltrop, Nick, Dujardin, Karl, Vanduynhoven, Philippe, Vermeersch, Paul, Pirlet, Charles, Hermans, Kurt, Van Reet, Bert, Ferdinande, Bert, Aminian, Adel, Dewilde, Willem, Guédès, Antoine, Simon, François, De Roeck, Frederic, De Vroey, Frédéric, Jukema, J. Wouter, Sinnaeve, Peter, and Buysschaert, Ian
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- 2024
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3. Impact of Diagnosis-to-Ablation Time on AF Recurrence: Pronounced the First 3 Years, Irrelevant Thereafter
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De Greef, Yves, Bogaerts, Kris, Sofianos, Dimitrios, and Buysschaert, Ian
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- 2023
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4. Incidence, Predictors, and Prognostic Impact of New Permanent Pacemaker Implantation After TAVR With Self-Expanding Valves
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Pagnesi, Matteo, Kim, Won-Keun, Baggio, Sara, Scotti, Andrea, Barbanti, Marco, De Marco, Federico, Adamo, Marianna, Eitan, Amnon, Estévez-Loureiro, Rodrigo, Conradi, Lenard, Toggweiler, Stefan, Mylotte, Darren, Veulemans, Verena, Søndergaard, Lars, Wolf, Alexander, Giannini, Francesco, Maffeo, Diego, Pilgrim, Thomas, Montorfano, Matteo, Zweiker, David, Ferlini, Marco, Kornowski, Ran, Hildick-Smith, David, Taramasso, Maurizio, Abizaid, Alexandre, Schofer, Joachim, Sinning, Jan-Malte, Van Mieghem, Nicolas M., Wöhrle, Jochen, Khogali, Saib, Van der Heyden, Jan A.S., Wood, David A., Ielasi, Alfonso, MacCarthy, Philip, Brugaletta, Salvatore, Hamm, Christian W., Costa, Giuliano, Testa, Luca, Massussi, Mauro, Alarcón, Robert, Schäfer, Ulrich, Brunner, Stephanie, Reimers, Bernhard, Lunardi, Mattia, Zeus, Tobias, Vanhaverbeke, Maarten, Naber, Christoph K., Di Ienno, Luca, Buono, Andrea, Windecker, Stephan, Schmidt, Albrecht, Lanzillo, Giuseppe, Vaknin-Assa, Hana, Arunothayaraj, Sandeep, Saccocci, Matteo, Siqueira, Dimytri, Brinkmann, Christina, Sedaghat, Alexander, Ziviello, Francesca, Seeger, Julia, Rottbauer, Wolfgang, Brouwer, Jorn, Buysschaert, Ian, Jelisejevas, Julius, Bharucha, Apurva, Regueiro, Ander, Metra, Marco, Colombo, Antonio, Latib, Azeem, and Mangieri, Antonio
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- 2023
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5. Bleeding and thrombotic risk of different antiplatelet regimens posttranscatheter edge‐to‐edge mitral valve repair in patients with an indication for oral anticoagulation: Results from an all‐comers national registry
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Claeys, Marc J., primary, Aminian, Adel, additional, Bartunek, Jozef, additional, Bennett, Johan, additional, Buysschaert, Ian, additional, Claeys, Mathias, additional, De Bock, Dina, additional, Delodder, Lies, additional, Debonnaire, Philippe, additional, Dewilde, Willem, additional, Ferdinande, Bert, additional, Geerinck, Stéphanie, additional, Goetschalckx, Kaatje, additional, Lambrechts, Olivier, additional, Lochy, Stijn, additional, Paelinck, Bernard P., additional, Rosseel, Liesbeth, additional, Stroobants, Didier, additional, Vanderheyden, Marc, additional, Van der Heyden, Jan, additional, Verbrugghe, Peter, additional, Verheye, Stefan, additional, and Dubois, Christophe, additional
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- 2023
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6. Bleeding and thrombotic risk of different antiplatelet regimens posttranscatheter edge‐to‐edge mitral valve repair in patients with an indication for oral anticoagulation: Results from an all‐comers national registry.
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Claeys, Marc J., Aminian, Adel, Bartunek, Jozef, Bennett, Johan, Buysschaert, Ian, Claeys, Mathias, De Bock, Dina, Delodder, Lies, Debonnaire, Philippe, Dewilde, Willem, Ferdinande, Bert, Geerinck, Stéphanie, Goetschalckx, Kaatje, Lambrechts, Olivier, Lochy, Stijn, Paelinck, Bernard P., Rosseel, Liesbeth, Stroobants, Didier, Vanderheyden, Marc, and Van der Heyden, Jan
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- 2024
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7. Comparison of transcatheter aortic valve replacement with the ACURATE neo2 versus Evolut PRO/PRO+ devices
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Baggio, Sara, Pagnesi, Matteo, Kim, Won Keun, Scotti, Andrea, Barbanti, Marco, Costa, Giuliano, Adamo, Marianna, Kornowski, Ran, Vaknin-Assa, Hana, Estévez-Loureiro, Rodrigo, Cedeño, Robert Alarcón, De Marco, Federico, Casenghi, Matteo, Toggweiler, Stefan, Veulemans, Verena, Mylotte, Darren, Lunardi, Mattia, Regazzoli, Damiano, Reimers, Bernhard, Sondergaard, Lars, Vanhaverbeke, Maarten, Nuyens, Philippe, Maffeo, Diego, Buono, Andrea, Saccocci, Matteo, Giannini, Francesco, Di Ienno, Luca, Ferlini, Marco, Lanzillo, Giuseppe, Ielasi, Alfonso, Schofer, Joachim, Brinkmann, Christina, Van Der Heyden, Jan, Buysschaert, Ian, Eitan, Amnon, Wolf, Alexander, Adamaszek, Martin Marian, Colombo, Antonio, Latib, Azeem, Mangieri, Antonio, Baggio, Sara, Pagnesi, Matteo, Kim, Won Keun, Scotti, Andrea, Barbanti, Marco, Costa, Giuliano, Adamo, Marianna, Kornowski, Ran, Vaknin-Assa, Hana, Estévez-Loureiro, Rodrigo, Cedeño, Robert Alarcón, De Marco, Federico, Casenghi, Matteo, Toggweiler, Stefan, Veulemans, Verena, Mylotte, Darren, Lunardi, Mattia, Regazzoli, Damiano, Reimers, Bernhard, Sondergaard, Lars, Vanhaverbeke, Maarten, Nuyens, Philippe, Maffeo, Diego, Buono, Andrea, Saccocci, Matteo, Giannini, Francesco, Di Ienno, Luca, Ferlini, Marco, Lanzillo, Giuseppe, Ielasi, Alfonso, Schofer, Joachim, Brinkmann, Christina, Van Der Heyden, Jan, Buysschaert, Ian, Eitan, Amnon, Wolf, Alexander, Adamaszek, Martin Marian, Colombo, Antonio, Latib, Azeem, and Mangieri, Antonio
- Abstract
Background: The ACURATE neo2 (NEO2) and Evolut PRO/PRO+ (PRO) bioprostheses are new-generation self-expanding valves developed for transcatheter aortic valve replacement (TAVR). Aims: We sought to compare the performance of the ACURATE neo2 and Evolut PRO/PRO+ devices. Methods: The NEOPRO-2 registry retrospectively included patients who underwent TAVR for severe aortic stenosis with either the NEO2 or PRO devices between August 2017 and December 2021 at 20 centres. In-hospital and 30-day Valve Academic Research Consortium (VARC)-3 defined outcomes were evaluated. Propensity score (PS) matching and binary logistic regression were performed to adjust the treatment effect for PS quintiles. A subgroup analysis assessed the impact of aortic valve calcification. Results: A total of 2,175 patients (NEO2: n=763; PRO: n=1,412) were included. The mean age was 82±6.2 years and the mean Society of Thoracic Surgeons score was 4.2%. Periprocedural complications were low, and both groups achieved high rates of technical success (93.1% vs 94.1%; p=0.361) and predischarge intended valve performance (96.0% vs 94.1%; p=0.056), both in the unmatched and matched analysis (452 pairs). Device success at 30 days was comparable (84.3% vs 83.6%; p=0.688), regardless of aortic valve calcification severity (p>0.05 for interaction). A suggestion for higher VARC-3 early safety in the NEO2 group was mainly driven by reduced rates of new permanent pacemaker implantation (7.7% vs 15.6%; p<0.001). Conclusions: This retrospective analysis reports a similar short-term performance of the ACURATE neo2 platform compared with the new-generation Evolut PRO/PRO+ devices. Randomised studies are needed to confirm our exploratory findings., Background: The ACURATE neo2 (NEO2) and Evolut PRO/PRO+ (PRO) bioprostheses are new-generation self-expanding valves developed for transcatheter aortic valve replacement (TAVR). Aims: We sought to compare the performance of the ACURATE neo2 and Evolut PRO/PRO+ devices. Methods: The NEOPRO-2 registry retrospectively included patients who underwent TAVR for severe aortic stenosis with either the NEO2 or PRO devices between August 2017 and December 2021 at 20 centres. In-hospital and 30-day Valve Academic Research Consortium (VARC)-3 defined outcomes were evaluated. Propensity score (PS) matching and binary logistic regression were performed to adjust the treatment effect for PS quintiles. A subgroup analysis assessed the impact of aortic valve calcification. Results: A total of 2,175 patients (NEO2: n=763; PRO: n=1,412) were included. The mean age was 82±6.2 years and the mean Society of Thoracic Surgeons score was 4.2%. Periprocedural complications were low, and both groups achieved high rates of technical success (93.1% vs 94.1%; p=0.361) and predischarge intended valve performance (96.0% vs 94.1%; p=0.056), both in the unmatched and matched analysis (452 pairs). Device success at 30 days was comparable (84.3% vs 83.6%; p=0.688), regardless of aortic valve calcification severity (p>0.05 for interaction). A suggestion for higher VARC-3 early safety in the NEO2 group was mainly driven by reduced rates of new permanent pacemaker implantation (7.7% vs 15.6%; p<0.001). Conclusions: This retrospective analysis reports a similar short-term performance of the ACURATE neo2 platform compared with the new-generation Evolut PRO/PRO+ devices. Randomised studies are needed to confirm our exploratory findings.
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- 2023
8. Comparison of transcatheter aortic valve replacement with the ACURATE neo2 versus Evolut PRO/PRO+ devices
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Baggio, Sara, primary, Pagnesi, Matteo, additional, Kim, Won-Keun, additional, Scotti, Andrea, additional, Barbanti, Marco, additional, Costa, Giuliano, additional, Adamo, Marianna, additional, Kornowski, Ran, additional, Vaknin Assa, Hana, additional, Estévez-Loureiro, Rodrigo, additional, Cedeño, Robert Alarcón, additional, De Marco, Federico, additional, Casenghi, Matteo, additional, Toggweiler, Stefan, additional, Veulemans, Verena, additional, Mylotte, Darren, additional, Lunardi, Mattia, additional, Regazzoli, Damiano, additional, Reimers, Bernhard, additional, Sondergaard, Lars, additional, Vanhaverbeke, Maarten, additional, Nuyens, Philippe, additional, Maffeo, Diego, additional, Buono, Andrea, additional, Saccocci, Matteo, additional, Giannini, Francesco, additional, Di Ienno, Luca, additional, Ferlini, Marco, additional, Lanzillo, Giuseppe, additional, Ielasi, Alfonso, additional, Schofer, Joachim, additional, Brinkmann, Christina, additional, Van Der Heyden, Jan, additional, Buysschaert, Ian, additional, Eitan, Amnon, additional, Wolf, Alexander, additional, Adamaszek, Martin Marian, additional, Colombo, Antonio, additional, Latib, Azeem, additional, and Mangieri, Antonio, additional
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- 2023
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9. Decisional Impact of CT-Based 3D Computational Modeling in Left Atrial Appendage Occlusion: The PRECISE LAAO.
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De Cock, Emmanuel, Lochy, Stijn, Rivero-Ayerza, Maximo, Lempereur, Mathieu, Cornelis, Kristoff, Debonnaire, Philippe, Vermeersch, Paul, Christiaen, Emma, and Buysschaert, Ian
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- 2024
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10. Clinical Impact of Preprocedural CT-Based 3D Computational Simulation of Left Atrial Appendage Occlusion with Amulet
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Buysschaert, Ian and Viaene, Dries
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Male ,Cardiac Catheterization ,Standard of care ,Article Subject ,medicine.medical_treatment ,Computed tomography ,030204 cardiovascular system & hematology ,Transoesophageal echocardiography ,Left atrial appendage occlusion ,Computational simulation ,03 medical and health sciences ,0302 clinical medicine ,Atrial Fibrillation ,medicine ,Diseases of the circulatory (Cardiovascular) system ,Humans ,Atrial Appendage ,Radiology, Nuclear Medicine and imaging ,030212 general & internal medicine ,Implanted device ,Aged ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,RC666-701 ,Female ,Degree of confidence ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,Nuclear medicine ,business ,Echocardiography, Transesophageal ,Modelling software ,Research Article - Abstract
Aims. Standard of care (SoC) device size selection with transoesophageal echocardiography (TOE) and computed tomography (CT) in LAAO can be challenging due to a certain degree of variability at both patient and device levels. The aim of this study was to prospectively evaluate the clinical impact of 3D computational modelling software in the decision-making of left atrial appendage occlusion (LAAO) with Amplatzer Amulet. Methods and Results. SoC preprocedural assessments as well as CT-based 3D computational simulations (FEops) were performed in 15 consecutive patients scheduled for LAAO with Amulet. Preprocedural device size selection and degree of confidence were determined after SoC and after FEops-based assessments and compared to the implanted device. FEops-based preprocedural assessment correctly selected the implanted device size in 11 out of 15 patients (73.3%), compared to 7 patients (46.7%) for SoC-based assessment. In 4 patients (26.7%), FEops induced a change in device size initially selected by SoC. In the 7 patients (46.7%) in which FEops confirmed the SoC device size selection, the degree of confidence of the size selection increased from 6.4 ± 1.4 for SoC to 8.1 ± 0.7 for FEops. One patient (6.7%) could not be implanted for anatomical reason, as correctly identified by FEops. Conclusions. Preprocedural 3D computational simulation by FEops impacts Amulet size selection in LAAO compared to TOE and CT-based SoC assessment. Operators could consider FEops computational simulation in their preprocedural device size selection.
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- 2021
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11. Optical Coherence Tomography Findings in Patients With Coronary Stent Thrombosis: A Report of the PRESTIGE Consortium (Prevention of Late Stent Thrombosis by an Interdisciplinary Global European Effort)
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Adriaenssens, Tom, Joner, Michael, Godschalk, Thea C., Malik, Nikesh, Alfonso, Fernando, Xhepa, Erion, De Cock, Dries, Komukai, Kenichi, Tada, Tomohisa, Cuesta, Javier, Sirbu, Vasile, Feldman, Laurent J., Neumann, Franz-Josef, Goodall, Alison H., Heestermans, Ton, Buysschaert, Ian, Hlinomaz, Ota, Belmans, Ann, Desmet, Walter, ten Berg, Jurrien M., Gershlick, Anthony H., Massberg, Steffen, Kastrati, Adnan, Guagliumi, Giulio, and Byrne, Robert A.
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- 2017
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12. Severe biventricular hypertrophy in MELAS mitochondrial disease
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Rosseel, Liesbeth, Breckpot, Jeroen, Debrauwere, Jan, Seneca, Sara, and Buysschaert, Ian
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- 2017
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13. Safety and Efficacy of the cobalt chromium PRO-Kinetik coronary stent system: Results of the MULTIBENE study
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Vermeersch, Paul, Appelman, Yolande, Horstkotte, Dieter, Richardt, Gert, Boland, Jean, Lalmand, Jacques, Coussement, Patrick, Castadot, Marc, Janssens, Luc, Agostoni, Pierfrancesco, Buysschaert, Ian, and Suttorp, Maarten J.
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- 2012
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14. Ticagrelor Monotherapy or Dual Antiplatelet Therapy After Drug‐Eluting Stent Implantation: Per‐Protocol Analysis of the GLOBAL LEADERS Trial
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Gragnano, Felice, primary, Zwahlen, Marcel, additional, Vranckx, Pascal, additional, Heg, Dik, additional, Schmidlin, Kurt, additional, Hamm, Christian, additional, Steg, Philippe Gabriel, additional, Gargiulo, Giuseppe, additional, McFadden, Eugene P., additional, Onuma, Yoshinobu, additional, Chichareon, Ply, additional, Benit, Edouard, additional, Möllmann, Helge, additional, Janssens, Luc, additional, Leonardi, Sergio, additional, Zurakowski, Aleksander, additional, Arrivi, Alessio, additional, Van Geuns, Robert Jan, additional, Huber, Kurt, additional, Slagboom, Ton, additional, Calabrò, Paolo, additional, Serruys, Patrick W., additional, Jüni, Peter, additional, Valgimigli, Marco, additional, Windecker, Stephan, additional, Abdellaoui, Mohamed, additional, Adlam, David, additional, Akin, Ibrahim, additional, Gonzalez‐Trevilla, Agustin Albarran, additional, Almeida, Manuel, additional, Neto, Pedro Alves Lemos, additional, Aminian, Adel, additional, Anderson, Richard, additional, Andreae, Rick, additional, Angioi, Michael, additional, Asano, Taku, additional, Barbato, Emanuele, additional, Barlis, Peter, additional, Barraud, Pascal, additional, Bertrand, Olivier, additional, Beygui, Farzin, additional, Bolognese, Leonardo, additional, Botelho, Roberto, additional, Bouwman, Coby, additional, Bressers, Marco, additional, Brunel, Philippe, additional, Buszman, Pawel, additional, Buysschaert, Ian, additional, da Silva, Pedro Canas, additional, Carrie, Didier, additional, Cequier, Angel, additional, Chang, Chun Chin, additional, Chowdhary, Saqib, additional, Collet, Carlos, additional, Colombo, Antonio, additional, Cotton, James, additional, Ferreira, Rui Cruz, additional, Curello, Salvatore, additional, Curzen, Nick, additional, de Bot, Judith, additional, de Vreede, Tone, additional, Karth, Georg Delle, additional, Dijksma, Lynn, additional, Dominici, Marcello, additional, Édes, István, additional, Eeckhout, Eric, additional, Eitel, Ingo, additional, Faluközy, József, additional, Fath‐Ordoubadi, Farzin, additional, Ferrario, Maurizio, additional, Fontos, Geza, additional, Diaz, Jose Francisco, additional, Quintella, Edgard Freitas, additional, Frey, Bernhard, additional, Friedrich, Guy, additional, Galasko, Gavin, additional, Galuszka, Grzegorz, additional, Ribeiro, Vasco Gama, additional, Garg, Scot, additional, Geisler, Tobias, additional, Gelev, Valeri, additional, Ghandilyan, Art, additional, Goicolea, Javier, additional, Gori, Tommaso, additional, Gragnano, Felice, additional, Guimarães, Ana, additional, Haude, Michael, additional, Heijke, Pieter, additional, Antolin, Rosa Ana Hernández, additional, Hildick‐Smith, David, additional, Hillen, Dorien, additional, Hoekman, Ina, additional, Hofma, Sjoerd, additional, Holmvang, Lene, additional, Hoole, Stephen, additional, Horváth, Iván, additional, Hugense, Annemarie, additional, Ibrahim, Karim, additional, Iñiguez, Andres, additional, Isaaz, Karl, additional, Jambrik, Zoltán, additional, Jasionowicz, Pawel, additional, Jonk, Judith, additional, Jung, Werner, additional, Katagiri, Yuki, additional, Kogame, Norihiro, additional, Koh, Tian Hai, additional, Koning, René, additional, Konteva, Mariana, additional, Kőszegi, Zsolt, additional, Krackhardt, Florian, additional, Kreuger, Yvonne, additional, Kukreja, Neville, additional, Ladan, Boudijn, additional, Lantelme, Pierre, additional, Leandro, Sergio, additional, Leibundgut, Gregor, additional, Liebetrau, Christoph, additional, Lindeboom, Wietze, additional, Miguel, Carlos Macaya, additional, Mach, François, additional, Magro, Michael, additional, Maillard, Luc, additional, Manavifar, Negar, additional, Mauri, Laura, additional, McFadden, Eugene, additional, Merkely, Bela, additional, Miyazaki, Yosuke, additional, Młodziankowski, Adam, additional, Moccetti, Tiziano, additional, Modolo, Rodrigo, additional, Möllman, Helge, additional, Morelle, Jean‐François, additional, Moschovitis, Aris, additional, Ottesen, Michael Munndt, additional, Muurling, Martin, additional, Naber, Christoph Kurt, additional, Neumann, Franz‐Josef, additional, Oldroyd, Keith, additional, Ong, Paul, additional, Palsrok, Sanne, additional, Petrov, Ivo, additional, Plante, Sylvain, additional, Prokopczuk, Janusz, additional, Rademaker‐Havinga, Tessa, additional, Raffel, Christopher, additional, Rensing, Benno, additional, Roffi, Marco, additional, Royaards, Kees‐Jan, additional, Sabate, Manel, additional, Schächinger, Volker, additional, Seidler, Tim, additional, Peñaranda, Antonio Serra, additional, Serruys, Patrick, additional, Sikarulidze, Lali, additional, Soliman, Osama I, additional, Sousa, Amanda, additional, Spitzer, Ernest, additional, Stables, Rod, additional, Steg, Gabriel, additional, Steinwender, Clemens, additional, Subkovas, Eduardas, additional, Suryapranata, Harry, additional, Takahashi, Kuniaki, additional, Talwar, Suneel, additional, Teiger, Emmanuel, additional, Weele, Addy Ter, additional, Teurlings, Eva, additional, Thury, Attila, additional, Tijssen, Jan, additional, Tonev, Gincho, additional, Trendafilova‐Lazarova, Diana, additional, Tumscitz, Carlo, additional, Umans, Victor, additional, Ungi, Imre, additional, Valkov, Veselin, additional, van der Harst, Pim, additional, van Geuns, Robert Jan, additional, van Meijeren, Cokky, additional, Vassilev, Dobrin, additional, Velchev, Vasil, additional, Velthuizen, Esther, additional, Verheugt, Freek, additional, Vlcek, Natalia, additional, Dahl, Jürgen Vom, additional, Vrolix, Mathias, additional, Walsh, Simon, additional, Werner, Nikos, additional, Witsenburg, Maarten, additional, Zaman, Azfar, additional, Żmudka, Krzysztof, additional, Zrenner, Bernhard, additional, and Zweiker, Robert, additional
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- 2022
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15. HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF
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Rolny, Charlotte, Mazzone, Massimiliano, Tugues, Sònia, Laoui, Damya, Johansson, Irja, Coulon, Cathy, Squadrito, Mario Leonardo, Segura, Inmaculada, Li, Xiujuan, Knevels, Ellen, Costa, Sandra, Vinckier, Stefan, Dresselaer, Tom, Åkerud, Peter, De Mol, Maria, Salomäki, Henriikka, Phillipson, Mia, Wyns, Sabine, Larsson, Erik, Buysschaert, Ian, Botling, Johan, Himmelreich, Uwe, Van Ginderachter, Jo A., De Palma, Michele, Dewerchin, Mieke, Claesson-Welsh, Lena, and Carmeliet, Peter
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- 2011
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16. Histopathological evaluation of thrombus in patients presenting with stent thrombosis. A multicenter European study: a report of the prevention of late stent thrombosis by an interdisciplinary global European effort consortium†
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Riegger, Julia, Byrne, Robert A., Joner, Michael, Chandraratne, Sue, Gershlick, Anthony H., ten Berg, Jurrien M., Adriaenssens, Tom, Guagliumi, Giulio, Godschalk, Thea C., Neumann, Franz-Josef, Trenk, Dietmar, Feldman, Laurent J., Steg, Philippe Gabriel, Desmet, Walter, Alfonso, Fernando, Goodall, Alison H., Wojdyla, Roman, Dudek, Dariusz, Philippi, Vanessa, Opinaldo, Sheryl, Titova, Anna, Malik, Nikesh, Cotton, James, Jhagroe, Darshni A., Heestermans, Antonius A.C.M., Sinnaeve, Peter, Vermeersch, Paul, Valina, Christian, Schulz, Christian, Kastrati, Adnan, Massberg, Steffen, Adriaenssens, Tom, Buysschaert, Ian, Chausson, Mickaël, De Cock, Dries, Dens, Jo, Barbato, Emanuele, Desmet, Walter, Gautier, Sandrine, Vermeersch, Paul, Sinnaeve, Peter, Abergel, Helene, Feldman, Laurent, Jandrot-Perrus, Martine, Letourneur, Didier, Mangin, Pierre, Olivier, Véronique, Roques, Caroline, Byrne, Robert A., Chandraratne, Sue, Gratz, Matthias, Joner, Michael, Kastrati, Adnan, Kennerknecht, Elisabeth, Konrad, Ildiko, Koppara, Tobias, Massberg, Steffen, Neumann, Franz-Josef, Ntziachristos, Vasilis, Opinaldo, Sheryl, Philippi, Vanessa, Riegger, Julia, Rosenthal, Amir, Rzany, Alexander, Schulz, Christian, Steigerwald, Kristin, Tada, Tomohiso, Titova, Anna, Trenk, Dietmar, Valina, Christian, Vogelsang, Andreas, Xhepa, Erion, Bernelli, Chiara, Coccato, Micol, Guagliumi, Giulio, Komukai, Kenichi, Sirbu, Vasile, Kerch, Garry, Amoroso, Giovanni, ten Berg, Jurriën, Dewilde, Willem J.M., Godschalk, Thea C., Heestermans, Antonius A.C.M., Jhagroe, Darshni A., Wykrzykowska, Joanne J., Winkens, Mark H.M., Dudek, Dariusz, Rzeszutko, Łukasz, Wojdyla, Roman, Zasada, Wojciech, Alfonso, Fernando, Cuesta, Javier, Medina, Miguel, Berry, Colin, Cotton, James, Curzen, Nick, McEntegart, Margaret, Gerber, Robert, Gershlick, Anthony, Goodall, Alison H., Hetherington, Simon, Hill, Jonathan, Kelly, Damian, Malik, Nikesh, Oldroyd, Keith, Routledge, Helen, Shannon, Joanne, Suresh, Venkatesan, and Zahman, Azfar
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- 2016
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17. TCT-382 Optical Coherence Tomography–Based Characterization of Neointimal Atherosclerotic Changes in Patients Presenting With Very Late Stent Thrombosis or In-Stent Restenosis
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Aytekin, Alp, primary, Nicol, Philipp, additional, Seguchi, Masaru, additional, Alfonso, Fernando, additional, Adriaenssens, Tom, additional, Nano, Nejva, additional, Feldman, Laurent, additional, Neumann, Franz-Josef, additional, Goodall, Alison H., additional, Chan Pin Yin, Dean, additional, Buysschaert, Ian, additional, Hlinomaz, Ota, additional, Desmet, Walter, additional, Berg, Jurrien Ten, additional, Massberg, Steffen, additional, Guagliumi, Giulio, additional, Byrne, Robert, additional, Joner, Michael, additional, Kastrati, Adnan, additional, and Xhepa, Erion, additional
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- 2021
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18. Benefit and Risks of Aspirin in Addition to Ticagrelor in Acute Coronary Syndromes: A Post Hoc Analysis of the Randomized GLOBAL LEADERS Trial
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Tomaniak, Mariusz, Chichareon, Ply, Onuma, Yoshinobu, Deliargyris, Efthymios N., Takahashi, Kuniaki, Kogame, Norihiro, Modolo, Rodrigo, Chang, Chun Ching, Rademaker-Havinga, Tessa, Storey, Robert F., Dangas, George D., Bhatt, Deepak L., Angiolillo, Dominick J., Hamm, Christian, Valgimigli, Marco, Windecker, Stephan, Steg, Philippe Gabriel, Vranckx, Pascal, Serruys, Patrick W., Bertrand, Olivier F., Plante, Sylvain, Van Geuns, Robert-Jan, Hofma, Sjoerd H., Royaards, Kees-Jan, Slagboom, Ton, Suryapranata, Harry, Umans, Victor A. W. M., Rensing, Benno, van der Harst, Pim, Magro, Michael, Barbato, Emanuel, Aminian, Adel, Benit, Edouard, Janssens, Luc, Vrolix, Mathias, Buysschaert, Ian, Carrie, Didier, Barraud, Pascal, Teiger, Emmanuel, Koning, Ren, Farzin, Beygui, Morelle, Jean-francois, Isaaz, Karl, Maillard, Luc, Abdellaoui, Mohamed, Brunel, Philippe, Angioi, Michael, Lantelme, Pierre, Sabate, Manel, Albarran Gonzalez-Trevilla, Agustin, Cardiology, Graduate School, ACS - Atherosclerosis & ischemic syndromes, ACS - Microcirculation, ACS - Heart failure & arrhythmias, and Cardiovascular Centre (CVC)
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Male ,Ticagrelor ,Internationality ,Time Factors ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Severity of Illness Index ,Tertiary Care Centers ,Coronary artery disease ,0302 clinical medicine ,Cause of Death ,030212 general & internal medicine ,610 Medicine & health ,Original Investigation ,Aspirin ,DUAL ANTIPLATELET THERAPY ,Continuity of Patient Care ,Clopidogrel ,Treatment Outcome ,CLOPIDOGREL ,Platelet aggregation inhibitor ,Drug Therapy, Combination ,Female ,Cardiology and Cardiovascular Medicine ,INTERVENTION ,medicine.drug ,Acute coronary syndrome ,medicine.medical_specialty ,Hemorrhage ,Risk Assessment ,Drug Administration Schedule ,03 medical and health sciences ,Percutaneous Coronary Intervention ,Internal medicine ,medicine ,Humans ,Acute Coronary Syndrome ,Dose-Response Relationship, Drug ,RECEPTOR ,business.industry ,Percutaneous coronary intervention ,IN-VITRO ,medicine.disease ,Survival Analysis ,PLATO ,Conventional PCI ,business ,Platelet Aggregation Inhibitors ,Follow-Up Studies - Abstract
Key PointsQuestionWhat are the benefits and risks of continuing aspirin in addition to P2Y12 receptor inhibition with ticagrelor among patients with acute coronary syndrome between 1 month and 12 months after percutaneous coronary intervention? FindingsIn this nonprespecified, post hoc analysis of the GLOBAL LEADERS randomized clinical trial, beyond 1 month after percutaneous coronary intervention in acute coronary syndrome, aspirin was associated with increased bleeding risk and appeared not to add to the benefit of ticagrelor on ischemic events. MeaningThe findings of this hypothesis-generating analysis pave the way for further trials evaluating aspirin-free antiplatelet strategies after percutaneous coronary intervention.ImportanceThe role of aspirin as part of antiplatelet regimens in acute coronary syndromes (ACS) needs to be clarified in the context of newer potent P2Y12 antagonists. ObjectiveTo evaluate the benefit and risks of aspirin in addition to ticagrelor among patients with ACS beyond 1 month after percutaneous coronary intervention (PCI). Design, Setting, and ParticipantsThis is a nonprespecified, post hoc analysis of GLOBAL LEADERS, a randomized, open-label superiority trial comparing 2 antiplatelet treatment strategies after PCI. The trial included 130 secondary/tertiary care hospitals in different countries, with 15991 unselected patients with stable coronary artery disease or ACS undergoing PCI. Patients had outpatient visits at 1, 3, 6, 12, 18, and 24 months after index procedure. InterventionsThe experimental group received aspirin plus ticagrelor for 1 month followed by 23-month ticagrelor monotherapy; the reference group received aspirin plus either clopidogrel (stable coronary artery disease) or ticagrelor (ACS) for 12 months, followed by 12-month aspirin monotherapy. In this analysis, we examined the clinical outcomes occurring between 31 days and 365 days after randomization, specifically in patients with ACS who, within this time frame, were assigned to receive either ticagrelor alone or ticagrelor and aspirin. Main Outcomes and MeasuresThe primary outcome was the composite of all-cause death or new Q-wave myocardial infarction. ResultsOf 15968 participants, there were 7487 patients with ACS enrolled; 3750 patients were assigned to the experimental group and 3737 patients to the reference group. Between 31 and 365 days after randomization, the primary outcome occurred in 55 patients (1.5%) in the experimental group and in 75 patients (2.0%) in the reference group (hazard ratio [HR], 0.73; 95% CI, 0.51-1.03; P=.07); investigator-reported Bleeding Academic Research Consortium-defined bleeding type 3 or 5 occurred in 28 patients (0.8%) in the experimental group and in 54 patients (1.5%) in the reference arm (HR, 0.52; 95% CI, 0.33-0.81; P=.004). Conclusions and RelevanceBetween 1 month and 12 months after PCI in ACS, aspirin was associated with increased bleeding risk and appeared not to add to the benefit of ticagrelor on ischemic events. These findings should be interpreted as exploratory and hypothesis generating; however, they pave the way for further trials evaluating aspirin-free antiplatelet strategies after PCI. Trial RegistrationClinicalTrials.gov identifier: NCT01813435.This secondary analysis of the GLOBAL LEADERS randomized clinical trial evaluates the benefit and risks of aspirin in addition to ticagrelor among patients with acute coronary syndrome beyond 1 month after percutaneous coronary intervention.
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- 2019
19. Baseline and 9 months IVUS analysis of the bifurcation-dedicated biolimus A9-eluting Axxess stent system: The DIVERGE IVUS substudy
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Buysschaert, Ian, Sanidas, Elias, Hasegawa, Takao, Koo, Bon-Kwon, Honda, Yasuhiro, Fitzgerald, Peter J., and Verheye, Stefan
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- 2014
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20. Feasibility and cost of FH cascade screening in Belgium (BEL-CASCADE) including a novel rapid rule-out strategy.
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UCL - (SLuc) Service de pathologie cardiovasculaire, Descamps, Olivier, Rietzschel, Ernst, Laporte, Anja, Buysschaert, Ian, De Raedt, Herbert, Elegeert, Ivan, Chenot, Fabien, Lengele, Jean-Philippe, Carlier, Stephane, Vanderheeren, Philippe, Lienart, Fabienne, Friart, Alain, Guillaume, Michel, Vandekerckhove, Hans, Maudens, Gunther, Mertens, Ann, van de Borne, Philippe, Bondue, Antoine, De Sutter, Johan, UCL - (SLuc) Service de pathologie cardiovasculaire, Descamps, Olivier, Rietzschel, Ernst, Laporte, Anja, Buysschaert, Ian, De Raedt, Herbert, Elegeert, Ivan, Chenot, Fabien, Lengele, Jean-Philippe, Carlier, Stephane, Vanderheeren, Philippe, Lienart, Fabienne, Friart, Alain, Guillaume, Michel, Vandekerckhove, Hans, Maudens, Gunther, Mertens, Ann, van de Borne, Philippe, Bondue, Antoine, and De Sutter, Johan
- Abstract
BACKGROUND: Familial hypercholesterolaemia (FH) is underdiagnosed in most countries. We report our first experience from a national pilot project of cascade screening in relatives of FH patients. METHODOLOGY: Participating specialists recruited consecutive index patients (IP) with Dutch Lipid Clinic Network (DLCN) score ≥6. After informed consent, the relatives were visited by the nurses to collect relevant clinical data and perform blood sampling for lipid profile measurement. FH diagnosis in the relatives was based on the DLCN and/or MEDPED FH (Make-Early-Diagnosis-to-Prevent-Early-Deaths-in-FH) criteria. RESULTS: In a period of 18 months, a total of 127 IP (90 with definite FH and 37 with probable FH) were enrolled in 15 centres. Out of the 270 relatives visited by the nurses, 105 were suspected of having FH: 31 with DCLN score >8, 33 with DLCN score 5-8 and 41 with MEDPED FH criteria. In a post-hoc analysis, another set of MEDPED FH criteria established in the Netherlands and adapted to Belgium allowed to detect FH in 51 additional relatives. CONCLUSION: In a country with no national FH screening program, our pilot project demonstrated that implementing a simple phenotypical FH cascade screening strategy using the collaboration of motivated specialists and two nurses, allowed to diagnose FH in 127 index patients and an additional 105 of their relatives over the two-year period. Newly developed MEDPED FH cut-offs, easily applicable by a nurse with a single blood sample, might further improve the sensitivity of detecting FH within families.
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- 2021
21. Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials
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Teerlink, John R., Diaz, Rafael, Felker, G. Michael, McMurray, John J.V., Metra, Marco, Solomon, Scott D., Adams, Kirkwood F., Anand, Inder, Arias‐Mendoza, Alexandra, Biering‐Sørensen, Tor, Böhm, Michael, Bonderman, Diana, Cleland, John G.F., Corbalan, Ramon, Crespo‐Leiro, Maria G., Dahlström, Ulf, Echeverria Correa, Luis E., Fang, James C., Filippatos, Gerasimos, Fonseca, Cândida, Goncalvesova, Eva, Goudev, Assen R., Howlett, Jonathan G., Lanfear, David E., Lund, Mayanna, Macdonald, Peter, Mareev, Vyacheslav, Momomura, Shin‐ichi, O'Meara, Eileen, Parkhomenko, Alexander, Ponikowski, Piotr, Ramires, Felix J. A., Serpytis, Pranas, Sliwa, Karen, Spinar, Jindrich, Suter, Thomas M., Tomcsanyi, Janos, Vandekerckhove, Hans, Vinereanu, Dragos, Voors, Adriaan A., Yilmaz, Mehmet B., Zannad, Faiez, Sharpsten, Lucie, Legg, Jason C., Abbasi, Siddique A., Varin, Claire, Malik, Fady I., Kurtz, Christopher E., Besada, Diego Alejandro, Majul, Claudio Rodolfo, Bruno, Marco Raul Litvak, Sassone, Sonia, Avaca, Horacio Alberto, Rasmussen, Mariela, Aiub, Jorge Roberto, Hominal, Miguel Angel, Perna, Eduardo, Duran, Ruben Omar Garcia, Schiavi, Lilia, Marquez, Lilia Luz Lobo, Vilamajo, Oscar Alberto Gomez, Mackinnon, Ignacio, Fuente, Ricardo Alfonso Leon, Montana, Oscar Romano, Novaretto, Leonardo, Guerrero, Rodolfo Andres Ahuad, Brasca, Daniela Garcia, Prado, Aldo, Garrido, Marcelo Alejandro, Luquez, Hugo, Martinez, Diego Felipe, Nicolosi, Liliana, Parody, Maria Leonor, Zaidman, Cesar, Berra, Fernando Colombo, Ibañez, Julio, Zapata, Gerardo, Caccavo, Alberto, Colque, Roberto, Diez, Mirta, Poy, Carlos, Salomone, Oscar Alejandro, Vogel, Daniel, Bordonava, Anselmo Paulino, Fernandez, Alberto, French, John, Atherton, John, Hamilton, Andrew, Begg, Alistair, Abhayaratna, Walter, Judkins, Christopher, De Pasquale, Carmine, McKenzie, Scott, Amerena, John, Szto, Gregory, Kearney, Leighton, Zimmet, Hendrik, Sverdlov, Aaron, Beltrame, John, Korczyk, Dariusz, Sindone, Andrew, Moertl, Deddo, Huber, Kurt, Huelsmann, Martin, Ablasser, Klemens, Ebner, Christian, Siostrzonek, Peter, Drexel, Heinz, Poelzl, Gerhard, Dujardin, Karl, Dupont, Matthias, Buysschaert, Ian, Lancellotti, Patrizio, Droogne, Walter, Chouchane, Iman, Silveira, Fabio, Rassi, Salvador, Reis, Gilmar, Filho, Pedro Pimentel, Simoes, Marcus Vinicius, Braga, Joao Carlos, Giorgeto, Flavio Eduardo, Ferraz, Almir, Jaeger, Cristiano Pederneiras, Saraiva, Jose Francisco, Tognon, Alexandre, Cardoso, Juliano, Greco, Oswaldo, Paiva, Maria Sanali, Paolino, Bruno, Filho, Otavio Coelho, Maia, Lilia Nigro, Silva, Rodrigo, Canesin, Manoel, Rossi, Paulo Roberto Ferreira, Fortes, Jose Augusto Ribas, Cerci, Rodrigo Julio, Manenti, Euler Roberto Fernandes, Leaes, Paulo Ernesto, Silva Neto, Luis Beck, Souza, Weimar Kunz Barroso, Bacal, Fernando, Chaves, Renato, Ramires, Felix, Vidotti, Maria Helena, Barros e Silva, Pedro Gabriel Melo, Piegas, Leopoldo Soares, Todorov, Georgi, Tzekova, Maria, Goudev, Assen, Mincheva, Valentina, Vasilev, Ivaylo, Tisheva‐ Gospodinova, Snezhanka, Petrov, Ivo, Postadzhiyan, Arman, Velikov, Chavdar, Dimov, Bojidar, Constance, Christian, Phaneuf, Denis‐Carl, Mielniczuk, Lisa, Pandey, A Shekhar, Senaratne, Manohara, Zieroth, Shelley, Savard, Daniel, Stewart, Robert, Huynh, Thao, Giannetti, Nadia, Moe, Gordon, Bourgeois, Ronald, Ezekowitz, Justin, Hartleib, Michael, Sussex, Bruce, Babapulle, Mohan, Chehayeb, Raja, Gaudet, Daniel, McKelvie, Robert, Nguyen, Viviane, Roth, Sherryn, Gupta, Milan, Pesant, Yves, Rupka, Dennis, Bhargava, Rakesh, Costa‐Vitali, Atilio, Proulx, Guy, Vega, Mario, Potthoff, Sergio, Cid, Maria Cristina Schnettler, Sepulveda, Alex Mauricio Villablanca, Zanetti, Fernando Tomas Lanas, Gajardo, Victor Areli Saavedra, Kindel, Carlos Conejeros, Jofre, Christian Paolo Pincetti, Segarra, Jorge Leonardo Cobos, Venegas, Manuel Eduardo Rodriguez, Hidalgo, Mario Yanez, Jalaf, Margarita Gertrudis Vejar, Li, Weimin, Zhang, Jinguo, Fu, Xin, Zhang, Xuelian, Li, Dongye, Wang, Zhifang, Qu, Yanling, Zheng, Zhe, Tang, Huifang, Yang, Ping, Zhang, Yuhui, Zheng, Yang, Mi, Yafei, Huang, He, Bu, Peili, Chen, Guoqin, Chen, Jiyan, Han, Yajun, Li, Zhangquan, Ma, Shumei, Yang, Xuming, Yuan, Zuyi, Dong, Yugang, Li, Zhaoping, Mahemuti, Ailiman, Niu, Wentang, Yang, Zhenyu, Zhang, Yuqing, Sun, Yuemin, Wu, Weiheng, Liu, Feng, Yan, Jing, Li, Yinjun, Wang, Yi, Zhang, Shouyan, Zhou, Changyong, Cui, Hanbin, Li, Jianjun, Li, Tianfa, Han, Qinghua, Wei, Yu, Correa, Luis Eduardo Echeverria, Mendoza, Jose Luis Accini, Jattin, Fernando Manzur, Osorio, Wilder Castaño, Luengas, Carlos Alberto, Arroyo, Julian Alonso Coronel, Corredor, Miguel Alfredo Moncada, Giraldo, Clara Ines Saldarriaga, Lopez, Rodrigo Botero, Salazar, Dora Ines Molina, Triana, Miguel Urina, Lopez, Luis Horacio Atehortua, Rojas, Pastor Olaya, Pelaez, Sebastian Velez, Pareja, Monica Lopez, Bonfanti, Alberto Cadena, Polasek, Rostislav, Monhart, Zdenek, Sochor, Karel, Motovska, Zuzana, Belohlavek, Jan, Busak, Ladislav, Krupicka, Jiri, Tyl, Petr, Jerabek, Ondrej, Podpera, Ivo, Skrobakova, Janka, Peterka, Karel, Spacek, Rudolf, Cech, Vladimir, Kellnerova, Ivana, Nechvatal, Libor, Pozdisek, Zbynek, Houra, Marek, Kryza, Radim, Machova, Vilma, Cepelak, Michal, Stepek, David, Zeman, Kamil, Klimsa, Zdenek, Koleckar, Pavel, Schee, Alexandr, Spinarova, Lenka, Coufal, Zdenek, Jeppesen, Jorgen, Vraa, Soren, Wiggers, Henrik, Nyvad, Ole, Nielsen, Tonny, Kaiser‐Nielsen, Peter, Videbaek, Lars, Galinier, Michel, Lefebvre, Jean‐Marie, Tartiere, Jean‐Michel, De Geeter, Guillaume, Roubille, Francois, Ricci, Jean Etienne, Salvat, Muriel, Gueffet, Jean‐Pierre, Decoulx, Eric, Berdague, Philippe, Jondeau, Guillaume, Ovize, Michel, Groote, Pascal De, Donal, Erwan, Isnard, Richard, Sabatier, Rémi, Trochu, Jean Noel, Damy, Thibaud, Georges, Jean‐Louis, Rosamel, Yann, Picard, François, Aboyans, Victor, Laperche, Thierry, Mitrovic, Veselin, Taggeselle, Jens, Störk, Stefan, Ebelt, Henning, Genth‐Zotz, Sabine, Rassaf, Tienush, Duengen, Hans‐Dirk, Mittag, Marcus, Menck, Niels, Zeymer, Uwe, Haehling, Stephan, Boehm, Michael, Frankenstein, Lutz, Killat, Holger, Bourhaial, Hakima, Beug, Daniel, Horacek, Thomas, Pfister, Roman, Sandri, Marcus, Westenfeld, Ralf, Kadel, Christoph, Karvounis, Haralambos, Patsilinakos, Sotirios, Mantas, Ioannis, Karavidas, Apostolos, Giamouzis, Grigorios, Tsioufis, Konstantinos, Naka, Katerina, Tziakas, Dimitrios, Parissis, John, Styliadis, Ioannis, Barbetseas, Ioannis, Manolis, Athanasios, Kochiadakis, George, Herczeg, Bela, Nagy, Laszlo, Nyolczas, Noemi, Toth, Kalman, Merkely, Bela, Laszlo, Zoltan, Mark, Laszlo, Szakal, Imre, Papp, Andras, Bezzegh, Katalin, Lakatos, Ferenc, Hajko, Erik, Papp, Aniko, Forster, Tamas, Lupkovics, Geza, Mohacsi, Attila, Salamon, Csaba, Aradi, Daniel, Andreka, Peter, Szasz, Gyula, Zilahi, Zsolt, Kazinczy, Rita, Margonato, Alberto, Agostoni, Piergiuseppe, Fucili, Alessandro, Piovaccari, Giancarlo, Senni, Michele, Carluccio, Erberto, Bilato, Claudio, Frigerio, Maria, Indolfi, Ciro, Sinagra, Gianfranco, Brunetti, Natale Daniele, Perna, Gianpiero, Pini, Daniela, Volterrani, Maurizio, Leonardi, Sergio, Mortara, Andrea, Friz, Hernan Emilio Francisco Polo, Rossini, Roberta, Tocchetti, Carlo Gabriele, Vincenzi, Antonella, Cavallini, Claudio, Floresta, Agata Marina, Zaca, Valerio, Giudici, Vittorio, Villani, Giovanni Quinto, Higashino, Yorihiko, Oishi, Shogo, Wada, Atsuyuki, Fukuzawa, Shigeru, Onoue, Kenji, Koike, Akihiro, Koizumi, Tomomi, Masuda, Seigo, Mitsuo, Kazuhisa, Takahashi, Natsuki, Takenaka, Takashi, Tanabe, Jun, Watanabe, Naoki, Yoshida, Takeshi, Amano, Tetsuya, Ishikawa, Masahiro, Kida, Keisuke, Kubota, Toru, Nakamura, Kentaro, Sakamoto, Tomohiro, Shimomura, Mitsuhiro, Yuge, Masaru, Doi, Masayuki, Domae, Hiroshi, Ebato, Mio, Fujii, Kenshi, Fujiwara, Wakaya, Gohara, Seiichiro, Hata, Yoshiki, Kanda, Junji, Kitaoka, Hiroaki, Matsumoto, Takashi, Michishita, Ichiro, Miura, Shinichiro, Miyazaki, Tetsuro, Nakamura, Akihiro, Ogawa, Tomohiro, Okumura, Takahiro, Okumura, Yasuo, Sakai, Tetsuo, Sato, Yukihito, Shimizu, Wataru, Sugino, Hiroshi, Suzuki, Masahiro, Takagi, Atsutoshi, Takaishi, Hiroshi, Tanaka, Takahiro, Terasaki, Toshiro, Tsujimoto, Mitsuru, Ueda, Yasunori, Ujino, Keiji, Usui, Makoto, Yamamoto, Mitsutaka, Yoshikawa, Masaki, Ando, Kenji, Asakura, Masanori, Asano, Hiroshi, Fujii, Shigeru, Hara, Hisao, Inomata, Takayuki, Isshiki, Takaaki, Kadokami, Toshiaki, Kai, Hisashi, Kasai, Toshio, Kawamitsu, Katsunori, Kawasaki, Tomohiro, Koga, Tokushi, Komiyama, Nobuyuki, Maejima, Yasuhiro, Manita, Mamoru, Miyamoto, Nobuhide, Node, Koichi, Numaguchi, Kotaro, Sakata, Yasushi, Serikawa, Takeshi, Takama, Noriaki, Tatebe, Shunsuke, Ueno, Hideki, Hidaka, Takayuki, Hiroi, Shitoshi, Iseki, Harukazu, Ito, Hiroshi, Kajinami, Kouji, Kawakami, Hideo, Momiyama, Yukihiko, Mori, Masuki, Morita, Yukiko, Okishige, Kaoru, Sakagami, Satoru, Takeishi, Yasuchika, Terasawa, Akihiro, Utsu, Noriaki, Badariene, Jolita, Celutkiene, Jelena, Slapikas, Rimvydas, Jarasuniene, Dalia, Castillo, Armando Garcia, De los Rios Ibarra, Manuel Odin, Lopez, Gabriel Arturo Ramos, Llamas, Edmundo Alfredo Bayram, Esperon, Guillermo Antonio Llamas, Vazquez, Eduardo Salcido, Gonzalez, Ricardo Garcia, Leon, Jose Luis Arenas, Gonzalez, Salvador Leon, Mendoza, Maria Alexandra Arias, Rodriguez, Alicia Contreras, Machado, Gustavo Francisco Mendez, Salazar, Melchor Alpizar, Ruiz, Alberto Esteban Bazzoni, Flores, Ana Maria De Leon, Carrasco, Jose Alfredo Pagola, Araiza, Raul Reyes, Römer, Tjeerd, Remmen, Johannes, Van Eck, Jacob, Elvan, Arif, Smilde, Tom, Voors, Adriaan, Wal, Ruud, Schaap, Jeroen, Sluis, Aize, Linssen, Gerardus, Magro, Michael, Willems, Frank, Hal, John, Zwaan, Coenraad, Beelen, Driek, Boswijk, Dirk, Hermans, Walter, Van Kesteren, Henricus, Scott, Russell, Hart, Hamish, Lund, Marianne, Szczasny, Marcin, Blicharski, Tomasz, Kafara, Mariusz, Stankiewicz, Anna, Skonieczny, Grzegorz, Zabowka, Maciej, Kania, Grzegorz, Kopaczewski, Jerzy, Pawlowicz, Lidia, Spyra, Janusz, Wlodarczyk, Aleksander, Sciborski, Ryszard, Balsam, Pawel, Drozdz, Jaroslaw, Sobkowicz, Bozena, Konieczynska, Malgorzata, Lelonek, Malgorzata, Bednarkiewicz, Zbigniew, Trebacz, Jaroslaw, Jankowski, Piotr, Sidor, Mateusz, Berkowski, Piotr, Chmielak, Zbigniew, Lenartowska, Lucyna, Nessler, Jadwiga, Straburzynska‐Migaj, Ewa, Kalarus, Zbigniew, Kowalski, Robert, Kalecinska‐Krystkiewicz, Ewa, Gola, Zbigniew, Pijanowski, Zbigniew, Wozakowska‐Kaplon, Beata, Cymerman, Krzysztof, Rynkiewicz, Andrzej, Miekus, Pawel, Monteiro, Pedro, Sarmento, Pedro Morais, Almeida, Filipa, Duarte, Tatiana, Fonseca, Candida, Oliveira, Luis, Santos, Luis, Brito, Dulce, Stanciulescu, Gabriela, Spiridon, Marilena Renata, Militaru, Constantin, Podoleanu, Cristian Gheorghe, Zdrenghea, Dumitru, Popescu, Mircea Ioachim, Macarie, Cezar‐Eugen, Giuca, Alina, Mitu, Florin, Voicu, Olga‐Cristina, Dorobantu, Maria, Lighezan, Daniel, Stamate, Sorin, Bykov, Alexander, Kobalava, Zhanna, Zrazhevskiy, Konstantin, Semenova, Irina, Vishnevsky, Alexander, Shutemova, Elena, Tereschenko, Sergey, Shvarts, Yury, Barbarash, Olga, Lukyanov, Yury, Voevoda, Mikhail, Dovgolis, Svetlana, Dronov, Dmitry, Goloshchekin, Boris, Sitnikova, Maria, Ezhov, Marat, Tarasov, Nikolay, Kotelnikov, Mikhail, Kostenko, Viktor, Solovev, Oleg, Goncharov, Ivan, Myasnikov, Roman, Rafalskiy, Vladimir, Ryabov, Vyacheslav, Kosmacheva, Elena, Motylev, Igor, Nosov, Vladimir, Osipova, Irina, Salukhov, Vladimir, Belenkiy, Dmitriy, Bolshakova, Olga, Pimenov, Leonid, Shilkina, Nataliya, Kulibaba, Elena, Repin, Alexey, Timofeev, Alexander, Mitrokhin, Vladislav, Sherenkov, Alexander, Arbolishvili, Georgy, Antalik, Lubomir, Dzupina, Andrej, Fulop, Peter, Majercak, Ivan, Gonsorcik, Jozef, Vinanska, Daniela, Lenner, Egon, Lukacova, Jana, Margoczy, Roman, Smik, Rudolf, Stevlik, Jan, Uhliar, Rudolf, Burgess, Lesley, Badat, Aysha, Klug, Eric, Van Zyl, Louis, Abelson, Mark, Moodley, Rajendran, Tsabedze, Nqoba, Fourie, Nyda, Bonet, Luis Almenar, Prado, Jose Maria Arizon, Oliveira Soares, Manue Martinez‐Selles D, Villota, Julio Eduardo Nuñez, Leiro, Maria Generosa Crespo, Juanatey, Jose Ramon Gonzalez, Figal, Domingo Andres Pascual, Palomas, Juan Luis Bonilla, Perez, Sonia Mirabet, Jimenez, Juan Francisco Delgado, Padron, Antonio Lara, Diaz, Victor Alfonso Jimenez, Cubero, Javier Segovia, Paya, Vicente Eduardo Climent, Mayoral, Alejandro Recio, Fuente Galan, Luis, Doblas, Juan Jose Gomez, Freire, Ramon Bover, Peiro, Maria Teresa Blasco, Molina, Beatriz Diaz, Martinez, Laura Jordan, Vilchez, Francisco Gonzalez, Boman, Kurt, Karlstrom, Patric, Berglund, Stefan, Szabo, Barna, Peterson, Magnus, Wodlin, Peter, Lindholm, Carl‐Johan, Moccetti, Tiziano, Mueller, Christian, Suter, Thomas, Hullin, Roger, Meyer, Philippe, Noll, Georg, Yigit, Zerrin, Turgut, Okan Onur, Bekar, Lutfu, Sahin, Tayfun, Koldas, Zehra Lale, Celik, Ahmet, Cavusoglu, Yuksel, Demir, Mesut, Onrat, Ersel, Duzenli, Mehmet, Cosansu, Kahraman, Muderrisoglu, Ibrahim Haldun, Tuncer, Mustafa, Badak, Ozer, Nalbantgil, Sanem, Kirma, Cevat, Okuyan, Ertugrul, Guray, Umit, Prokhorov, Oleksandr, Karpenko, Oleksandr, Vakaliuk, Igor, Yagensky, Andriy, Kracz, Igor, Stanislavchuk, Mykola, Kulynych, Oleksii, Rishko, Mykola, Stets, Roman, Tseluyko, Vira, Mishchenko, Larysa, Rudenko, Leonid, Rudyk, Iurii, Alieksieieva, Liudmyla, Korzh, Oleksii, Mostovoy, Yuriy, Parkhomenko, Oleksandr, Rasputina, Lesya, Voronkov, Leonid, Lymar, Yurii, Vasilyeva, Larysa, Keeling, Philip, Barr, Craig, Wong, Kenneth, Price, Dallas, Skaria, Binoy, Clark, Andrew, Chandrasekaran, Badrinathan, Trevelyan, Jasper, Gordon, Brian, Donnelly, Patrick, Glover, Jason, Ryding, Alisdair, Weir, Robin, Lang, Chim, Roy, Debashis, Adhya, Shaumik, Clifford, Piers, Ludman, Andrew, Kalra, Paul, Lynch, Mary, Mahmood, Shahid, Al Mohammad, Abdallah, Asubiaro, Joshua, Elmahi, Einas, Muthumala, Amal, Taylor, Justin, Gupta, Dinesh, Nadar, Venkatesh, Henderson, David, Zolty, Ronald, Sauer, Andrew, Adams, Kirkwood, Chandra, Lokesh, Jaffrani, Naseem, Grewal, Gurinder, Mancini, Donna, McLean, Dalton, Vasallo, Javier, Gottlieb, Stephen, Joseph, Susan, Barua, Rajat, Gorodeski, Eiran, Mouhaffel, Asad, Chung, Eugene, Desai, Pratik, Portnay, Edward, Rama, Bhola, Shandling, Adrian, Stahl, Llyod, Heilman, Karl, Jacob, Binu, Londono, Juan, Almousalli, Omar, Ashcom, Thomas, Bauerlein, Eugene Joseph, Koo, Charles, McGrew, Frank, Rajagopalan, Navin, Robinson, Shawn, Schultz, David, Starling, Randall, Ambardekar, Amrut, Bhagwat, Ravi, Boehmer, John, Bouza, Manuel, Farris, Neil, Feitell, Scott, Ganji, Jagadeesh, Geltman, Edward, Javier, Julian, Morrow, John Andrew, Pianko, Leonard, Smart, Frank, Adler, Alexander, Brinkley, Douglas, Cardona, Jose, Coletti, Andrew, Harris, John, Hunter, Vernon, Krantz, Mori, Lang, Christopher, Lovell, Charles, Murray, David, Pillutla, Priya, Shah, Amit, Bogaev, Roberta, Dauber, Ira, Franchi, Francesco, Fremont, Richard, Hart, Terence, Hattler, Brack, Janik, Matthew, Khalife, Wissam, Malhotra, Sanjay, Mamdani, Shafiq, Nelson, William, Orgera, Marisa, Ortiz, Aurelio, Rahko, Peter, Rennyson, Stephen, Shin, Jooyoung, Tsao, Lana, Uretsky, Barry, Wahid, Faisal, Wilkett, Matt, Amanullah, Aman, Baker, Mathue, Berk, Martin, Boccalandro, Fernando, Cruz, Kimberly, Doyle, Timothy, Gianfagna, Robert, Jones, Alonzo, King, Anthony, Lepor, Norman, Martinez‐Castrillon, Melvin, Pham, Michael, Radin, Michael, Radojevic, Joseph, Ramanathan, Kodangudi, Schmalfuss, Carsten, Schnitzler, Robert, Shah, Keyur, Takata, Theodore, Bertolet, Barry, Bostick, Brian, Civitello, Andrew, Collins, John, Dib, Nabil, Fang, James, Gilmore, Richard, Gray, Wayne, Grazette, Luanda, Haddad, Tariq, Hearne, Steven, Janmohamed, Munir, Katz, Richard, Kazemi, Navid, Llerena, Sara, Lohr, Nicole, Marzouka, George, Mignone, John, Ooi, Henry, Paszczuk, Anna, Pickett, Christopher, Sampognaro, Gregory, Sawyer, Douglas, Shayani, Steven, Treasure, Charles, Vaz, Garth, Vijay, Nampalli, Williams, Celeste, Yeoman, Gary, Zhang, Lily, Aaronson, Keith, Abo‐Auda, Wael, Alharethi, Rami, Anderson, William, Ariani, Mehrdad, Banerji, Sourin, Baweja, Paramdeep, Carson, Peter, Eberly, Arthur, Elliott, James, Fernando, Ronald, Fisher, Daniel, Forman, Steven, Gabriel, George, Gogia, Harinder, Hametz, Craig, Houston, Brian, Ibrahim, Hassan, Jadbabaie, Farid, Kassiotis, Christos, Krishnamoorthy, Arun, Kwan, Michael, Lupovitch, Steven, Macias, Leonardo, Malik, Adnan, Martinez, Luis, Miyamoto, Michael, Mody, Freny, Patel, Devesh, Peart, Brenda, Pisani, Barbara, Ramos, Mark, Rivero, Mariel, Shah, Anil, Sharma, Mukesh, Sichrovsky, Tina, Simon, Marc, Singh, Deovrat, Tallet, Julio, Vaccari, Christopher, Villoch, Mario, Wheeler, Matthew, Yousuf, Kabir, Abadier, Rafik, Abdullah, Shuaib, Arora, Raveen, Aslam, Shamaila, Buynak, Robert, Chang, David, Contreras, Johanna, Halpern, Stephen, Handel, Franklin, Heitner, John, Herzog, William, Jackson, Bruce, Kao, John, Kondo, Nicholas, Koren, Michael, LeWinter, Martin, Martindale, Jeffrey, Martinez‐Arraras, Joaquin, Olsen, Stephanie, Piatek, Marek, Ranadive, Nandkishore, Randall, William, Rao, Sunder, Rawitscher, David, Rider, James, Sokos, George, Strader, J Russell, Sulemanjee, Nasir, Tahirkheli, Naeem, Trichon, Benjamin, Vanhecke, Thomas, Whellan, David, Abuannadi, Mohammad, Aggarwala, Gaurav, Ahmad, Saad, Artis, Andre, Cheirif, Jorge, Cotarlan, Vladimir, Cox, Jeremy, Eaton, Charles, Florea, Viorel, Frank, Theodore, Friedman, Keith, Ganeshram, Vedampattu, Gass, Alan, Gemignani, Anthony, Hasni, Syed, Hedgepeth, Chester, Itchhaporia, Dipti, Kaluski, Edo, Karim, Amin, Kono, Alan, Lader, Ellis, Lakshminarayanan, Batlagundu, Lewis, Neil, Malhotra, Vinay, Mayer, Nolan, Mohapatra, Robert, Nair, Nandini, O'Brien, Terrence, Pauwaa, Sunil, Rowan, Christopher, Saxena, Sanjeev, Seto, Arnold, Shah, Nishant, Singh, Pradeep, Skopicki, Hal, Stoddard, Marcus, and Sweitzer, Nancy
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R1 - Abstract
Aims:\ud The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials.\ud \ud Methods and Results:\ud Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure
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- 2020
22. Feasibility and cost of FH cascade screening in Belgium (BEL-CASCADE) including a novel rapid rule-out strategy
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Descamps, Olivier S., Rietzschel, Ernst Robert, Laporte, Anja, Buysschaert, Ian, De Raedt, Herbert, Elegeert, Ivan, Chenot, Fabien, Lengele, Jean Philippe, Carlier, Stéphane, Vanderheeren, Philippe, Liénart, Fabienne, Friart, Alain, Guillaume, Michel, Vandekerckhove, Hans, Maudens, Gunther, Mertens, Anna A.H., Van De Borne, Philippe, Bondue, Antoine, De Sutter, Johan, Descamps, Olivier S., Rietzschel, Ernst Robert, Laporte, Anja, Buysschaert, Ian, De Raedt, Herbert, Elegeert, Ivan, Chenot, Fabien, Lengele, Jean Philippe, Carlier, Stéphane, Vanderheeren, Philippe, Liénart, Fabienne, Friart, Alain, Guillaume, Michel, Vandekerckhove, Hans, Maudens, Gunther, Mertens, Anna A.H., Van De Borne, Philippe, Bondue, Antoine, and De Sutter, Johan
- Abstract
Background: Familial hypercholesterolaemia (FH) is underdiagnosed in most countries. We report our first experience from a national pilot project of cascade screening in relatives of FH patients. Methodology: Participating specialists recruited consecutive index patients (IP) with Dutch Lipid Clinic Network (DLCN) score ≥6. After informed consent, the relatives were visited by the nurses to collect relevant clinical data and perform blood sampling for lipid profile measurement. FH diagnosis in the relatives was based on the DLCN and/or MEDPED FH (Make-Early-Diagnosis-to-Prevent-Early-Deaths-in-FH) criteria. Results: In a period of 18 months, a total of 127 IP (90 with definite FH and 37 with probable FH) were enrolled in 15 centres. Out of the 270 relatives visited by the nurses, 105 were suspected of having FH: 31 with DCLN score >8, 33 with DLCN score 5-8 and 41 with MEDPED FH criteria. In a post-hoc analysis, another set of MEDPED FH criteria established in the Netherlands and adapted to Belgium allowed to detect FH in 51 additional relatives. Conclusion: In a country with no national FH screening program, our pilot project demonstrated that implementing a simple phenotypical FH cascade screening strategy using the collaboration of motivated specialists and two nurses, allowed to diagnose FH in 127 index patients and an additional 105 of their relatives over the two-year period. Newly developed MEDPED FH cut-offs, easily applicable by a nurse with a single blood sample, might further improve the sensitivity of detecting FH within families., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2020
23. Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation
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Researchgr. Cardiovasculaire Radiologie, Team Medisch, Circulatory Health, Brouwer, Jorn, Nijenhuis, Vincent J., Delewi, Ronak, Hermanides, Renicus S., Holvoet, Wouter, Dubois, Christophe L. F., Frambach, Peter, De Bruyne, Bernard, van Houwelingen, Gert K., Van der Heyden, Jan A. S., Tousek, Petr, van der Kley, Frank, Buysschaert, Ian, Schotborgh, Carl E., Ferdinande, Bert, van der Harst, Pim, Roosen, John, Peper, Joyce, Thielen, Frederick W. F., Veenstra, Leo, Yin, Dean R. P. P. Chan Pin, Swaans, Martin J., Rensing, Benno J. W. M., van 't Hof, Arnoud W. J., Timmers, Leo, Kelder, Johannes C., Stella, Pieter R., Baan, Jan, ten Berg, Jurrien M., Researchgr. Cardiovasculaire Radiologie, Team Medisch, Circulatory Health, Brouwer, Jorn, Nijenhuis, Vincent J., Delewi, Ronak, Hermanides, Renicus S., Holvoet, Wouter, Dubois, Christophe L. F., Frambach, Peter, De Bruyne, Bernard, van Houwelingen, Gert K., Van der Heyden, Jan A. S., Tousek, Petr, van der Kley, Frank, Buysschaert, Ian, Schotborgh, Carl E., Ferdinande, Bert, van der Harst, Pim, Roosen, John, Peper, Joyce, Thielen, Frederick W. F., Veenstra, Leo, Yin, Dean R. P. P. Chan Pin, Swaans, Martin J., Rensing, Benno J. W. M., van 't Hof, Arnoud W. J., Timmers, Leo, Kelder, Johannes C., Stella, Pieter R., Baan, Jan, and ten Berg, Jurrien M.
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- 2020
24. Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation
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Circulatory Health, Team Medisch, Nijenhuis, Vincent J, Brouwer, Jorn, Delewi, Ronak, Hermanides, Renicus S, Holvoet, Wouter, Dubois, Christophe L F, Frambach, Peter, De Bruyne, Bernard, van Houwelingen, Gert K, Van Der Heyden, Jan A S, Toušek, Petr, van der Kley, Frank, Buysschaert, Ian, Schotborgh, Carl E, Ferdinande, Bert, van der Harst, Pim, Roosen, John, Peper, Joyce, Thielen, Frederick W F, Veenstra, Leo, Chan Pin Yin, Dean R P P, Swaans, Martin J, Rensing, Benno J W M, van 't Hof, Arnoud W J, Timmers, Leo, Kelder, Johannes C, Stella, Pieter R, Baan, Jan, Ten Berg, Jurriën M, Circulatory Health, Team Medisch, Nijenhuis, Vincent J, Brouwer, Jorn, Delewi, Ronak, Hermanides, Renicus S, Holvoet, Wouter, Dubois, Christophe L F, Frambach, Peter, De Bruyne, Bernard, van Houwelingen, Gert K, Van Der Heyden, Jan A S, Toušek, Petr, van der Kley, Frank, Buysschaert, Ian, Schotborgh, Carl E, Ferdinande, Bert, van der Harst, Pim, Roosen, John, Peper, Joyce, Thielen, Frederick W F, Veenstra, Leo, Chan Pin Yin, Dean R P P, Swaans, Martin J, Rensing, Benno J W M, van 't Hof, Arnoud W J, Timmers, Leo, Kelder, Johannes C, Stella, Pieter R, Baan, Jan, and Ten Berg, Jurriën M
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- 2020
25. Influence of 23 coronary artery disease variants on recurrent myocardial infarction or cardiac death: the GRACE Genetics Study
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Wauters, Els, Carruthers, Kathryn F., Buysschaert, Ian, Dunbar, Donald R., Peuteman, Gilian, Belmans, Ann, Budaj, Andrzej, Van de Werf, Frans, Lambrechts, Diether, and Fox, Keith A. A.
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- 2013
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26. Late coronary sequels of Kawasaki Disease
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Buysschaert, Ian and Vermeersch, Paul
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- 2012
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27. Stone heart or apical retraction and calcification in Chagasʼ cardiomyopathy
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Buysschaert, Ian, De Keyser, Jan, and Dujardin, Karl
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- 2012
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28. Hypertensive crisis and end-organ damage induced by over-the-counter nasal decongestant abuse
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Buysschaert, Ian, Van Dorpe, Jo, and Dujardin, Karl
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- 2011
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29. Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation
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Brouwer, Jorn, primary, Nijenhuis, Vincent J., additional, Delewi, Ronak, additional, Hermanides, Renicus S., additional, Holvoet, Wouter, additional, Dubois, Christophe L.F., additional, Frambach, Peter, additional, De Bruyne, Bernard, additional, van Houwelingen, Gert K., additional, Van Der Heyden, Jan A.S., additional, Toušek, Petr, additional, van der Kley, Frank, additional, Buysschaert, Ian, additional, Schotborgh, Carl E., additional, Ferdinande, Bert, additional, van der Harst, Pim, additional, Roosen, John, additional, Peper, Joyce, additional, Thielen, Frederick W.F., additional, Veenstra, Leo, additional, Chan Pin Yin, Dean R.P.P., additional, Swaans, Martin J., additional, Rensing, Benno J.W.M., additional, van ’t Hof, Arnoud W.J., additional, Timmers, Leo, additional, Kelder, Johannes C., additional, Stella, Pieter R., additional, Baan, Jan, additional, and ten Berg, Jurriën M., additional
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- 2020
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30. Feasibility and cost of FH cascade screening in Belgium (BEL-CASCADE) including a novel rapid rule-out strategy
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Descamps, Olivier S., primary, Rietzschel, Ernst, additional, Laporte, Anja, additional, Buysschaert, Ian, additional, De Raedt, Herbert, additional, Elegeert, Ivan, additional, Chenot, Fabien, additional, Lengele, Jean-Philippe, additional, Carlier, Stephane, additional, Vanderheeren, Philippe, additional, Lienart, Fabienne, additional, Friart, Alain, additional, Guillaume, Michel, additional, Vandekerckhove, Hans, additional, Maudens, Gunther, additional, Mertens, Ann, additional, van de Borne, Philippe, additional, Bondue, Antoine, additional, and De Sutter, Johan, additional
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- 2020
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31. On the verge of a tearable complication following acute myocardial infarction: aborted ventricular septal rupture
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Risseeuw, Florentijn, primary, Hermans, Hadewich, additional, and Buysschaert, Ian, additional
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- 2020
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32. Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation
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Nijenhuis, Vincent J., primary, Brouwer, Jorn, additional, Delewi, Ronak, additional, Hermanides, Renicus S., additional, Holvoet, Wouter, additional, Dubois, Christophe L.F., additional, Frambach, Peter, additional, De Bruyne, Bernard, additional, van Houwelingen, Gert K., additional, Van Der Heyden, Jan A.S., additional, Toušek, Petr, additional, van der Kley, Frank, additional, Buysschaert, Ian, additional, Schotborgh, Carl E., additional, Ferdinande, Bert, additional, van der Harst, Pim, additional, Roosen, John, additional, Peper, Joyce, additional, Thielen, Frederick W.F., additional, Veenstra, Leo, additional, Chan Pin Yin, Dean R.P.P., additional, Swaans, Martin J., additional, Rensing, Benno J.W.M., additional, van ’t Hof, Arnoud W.J., additional, Timmers, Leo, additional, Kelder, Johannes C., additional, Stella, Pieter R., additional, Baan, Jan, additional, and ten Berg, Jurriën M., additional
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- 2020
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33. Underestimated and under-recognized: the late consequences of acute coronary syndrome (GRACE UK–Belgian Study)
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Fox, Keith A.A., Carruthers, Kathryn F., Dunbar, Donald R., Graham, Catriona, Manning, Jonathan R., De Raedt, Herbert, Buysschaert, Ian, Lambrechts, Diether, and Van de Werf, Frans
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- 2010
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34. The Association of the 4q25 Susceptibility Variant for Atrial Fibrillation With Stroke Is Limited to Stroke of Cardioembolic Etiology
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Lemmens, Robin, Buysschaert, Ian, Geelen, Veerle, Fernandez-Cadenas, Israel, Montaner, Joan, Schmidt, Helena, Schmidt, Reinhold, Attia, John, Maguire, Jane, Levi, Christopher, Jood, Katarina, Blomstrand, Christian, Jern, Christina, Wnuk, Marcin, Slowik, Agniezska, Lambrechts, Diether, and Thijs, Vincent
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- 2010
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35. A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: The GRACE Genetics Study
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Buysschaert, Ian, Carruthers, Kathryn F., Dunbar, Donald R., Peuteman, Gilian, Rietzschel, Ernst, Belmans, Ann, Hedley, Ann, De Meyer, Tim, Budaj, Andrzej, Van de Werf, Frans, Lambrechts, Diether, and Fox, Keith A.
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- 2010
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36. Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions
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Roncal, Carmen, Buysschaert, Ian, Gerdes, Norbert, Georgiadou, Maria, Ovchinnikova, Olga, Fischer, Christian, Stassen, Jean-Marie, Moons, Lieve, Collen, Désiré, De Bock, Katrien, Hansson, Göran K., and Carmeliet, Peter
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- 2010
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37. The 15q24/25 Susceptibility Variant for Lung Cancer and Chronic Obstructive Pulmonary Disease Is Associated with Emphysema
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Lambrechts, Diether, Buysschaert, Ian, Zanen, Pieter, Coolen, Johan, Lays, Natacha, Cuppens, Harry, Groen, Harry J. M., Dewever, Walter, van Klaveren, Rob J., Verschakelen, Johny, Wijmenga, Cisca, Postma, Dirkje S., Decramer, Marc, and Janssens, Wim
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- 2010
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38. Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene
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Janssens, Wim, Bouillon, Roger, Claes, Bart, Carremans, Claudia, Lehouck, An, Buysschaert, Ian, Coolen, Johan, Mathieu, Chantal, Decramer, Marc, and Lambrechts, Diether
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- 2010
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39. Genetics, epigenetics and pharmaco-(epi)genomics
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Buysschaert, Ian, Schmidt, Thomas, Roncal, Carmen, Carmeliet, Peter, and Lambrechts, Diether
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- 2008
40. Contribution of 18fluoro-deoxyglucose positron emission tomography to the work-up of patients with fever of unknown origin
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Buysschaert, Ian, Vanderschueren, Steven, Blockmans, Daniël, Mortelmans, Luc, and Knockaert, Daniël
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- 2004
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41. Complications of pulmonary vein isolation in atrial fibrillation: predictors and comparison between four different ablation techniques: Results from the Mlddelheim PVI-registry
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De Greef, Yves, Ströker, Edwin, Bruno, Schwagten, Kupics, Kaspars, De Cocker, Jeroen, Chierchia, Gian-Battista, de Asmundis, Carlo, Stockman, Dirk, Buysschaert, Ian, Faculty of Medicine and Pharmacy, Heartrhythmmanagement, and Clinical sciences
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safety ,Physiology (medical) ,Atrial Fibrillation ,Electro-anatomical mapping system ,Major complication rate ,Cardiology and Cardiovascular Medicine ,Pulmonary vein isolation - Abstract
Aims: To define predictors of complications of pulmonary vein isolation (PVI) and compare safety between different ablation techniques. Methods and results: One thousand patients with atrial fibrillation (AF) (age 60 ± 10, 72% males, CHA2DS2-VASc score 1 ± 1) underwent PVI using various techniques: conventional PVI (CPVI) using mapping with irrigated point-per-point RF ablation (n = 576), multi-electrode RF ablation with the pulmonary vein ablation catheter (PVAC) (n = 272) or high density mesh ablator (HDMA) (n = 59) and cryoballoon (CB) ablation (n = 93). A complication was defined as any procedure-related adverse event resulting in permanent injury or death, requiring intervention or treatment, or prolonging/requiring hospitalization for >48 h. A total of 105 (10.5%) complications occurred in 101 (10.1%) patients. No periprocedural death occurred. Most frequent complications were vascular complications (4%) and pericarditis (3.1%). Seven patients experienced permanent deficit due to PV stenosis (n = 3, 1 CPVI, 2 PVAC) (n = 3) and phrenic nerve palsy (PNP) (n = 4, 3 CPVI, 1 PVAC). Independent predictors of complications were female sex [odds ratio (OR) = 1.73; 95% confidence interval (CI) 1.08-2.79; P = 0.023], CHA2DS2-VASc score (OR = 1.24; 95% CI 1.01-1.52; P = 0.039), and ablation technique (P = 0.006) in multivariable-adjusted analysis. Among the different techniques, CB (P = 0.047) and PVAC ablation (P = 0.003) had lowest overall complication rates. Complication profile (type/severity) differed between techniques (association between CB and PNP, CPVI and pericardial injury, PVAC and transient ischaemic attack/PV stenosis). Conclusion: Overall complication rate of PVI with various techniques is 10.5%. Permanent deficit occurred only after PVAC and CPVI in 0.7% of patients. Female sex and a higher CHA2DS2-VASc score increase, while PVAC and CB-PVI decrease, overall risk. Differences in overall safety and individual complication profile make selection of the ablation technique in relation to clinical risk profile possible.
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- 2018
42. Predictive ability of ACEF and ACEF II score in patients undergoing percutaneous coronary intervention in the GLOBAL LEADERS study
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Chichareon, Ply, primary, Modolo, Rodrigo, additional, van Klaveren, David, additional, Takahashi, Kuniaki, additional, Kogame, Norihiro, additional, Chang, Chun-Chin, additional, Katagiri, Yuki, additional, Tomaniak, Mariusz, additional, Asano, Taku, additional, Spitzer, Ernest, additional, Buszman, Pawel, additional, Prokopczuk, Janusz, additional, Fath-Ordoubadi, Farzin, additional, Buysschaert, Ian, additional, Anderson, Richard, additional, Oldroyd, Keith G., additional, Merkely, Bela, additional, Garg, Scot, additional, Wykrzykowska, Joanna J., additional, Piek, Jan J., additional, Jüni, Peter, additional, Hamm, Christian, additional, Steg, Philippe Gabriel, additional, Valgimigli, Marco, additional, Vranckx, Pascal, additional, Windecker, Stephan, additional, Onuma, Yoshinobu, additional, and Serruys, Patrick W., additional
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- 2019
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43. Feasibility and cost of FH cascade screening in Belgium (BEL-CASCADE) including a novel rapid rule-out strategy.
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Descamps, Olivier S., Rietzschel, Ernst, Laporte, Anja, Buysschaert, Ian, De Raedt, Herbert, Elegeert, Ivan, Chenot, Fabien, Lengele, Jean-Philippe, Carlier, Stephane, Vanderheeren, Philippe, Lienart, Fabienne, Friart, Alain, Guillaume, Michel, Vandekerckhove, Hans, Maudens, Gunther, Mertens, Ann, van de Borne, Philippe, Bondue, Antoine, and De Sutter, Johan
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- 2021
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44. Transcatheter left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation: results from the Belgian registry.
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UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de cardiologie, Kefer, Joelle, Aminian, Adel, Vermeersch, Paul, de Potter, Tom, Stammen, Francis, Benit, Edouard, Budts, Werner, Missault, Luc, Drieghe, Benny, Buysschaert, Ian, Cornelis, Kristoff, Herzet, Jean-Manuel, Guedes, Antoine, Debbas, Nadia, Rivero, Maximo, Lempereur, Mathieu, Lochy, Stijn, Casado-Arroyo, Ruben, Laruelle, Christophe, Debruyne, Philippe, Ledent, Thierry, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de cardiologie, Kefer, Joelle, Aminian, Adel, Vermeersch, Paul, de Potter, Tom, Stammen, Francis, Benit, Edouard, Budts, Werner, Missault, Luc, Drieghe, Benny, Buysschaert, Ian, Cornelis, Kristoff, Herzet, Jean-Manuel, Guedes, Antoine, Debbas, Nadia, Rivero, Maximo, Lempereur, Mathieu, Lochy, Stijn, Casado-Arroyo, Ruben, Laruelle, Christophe, Debruyne, Philippe, and Ledent, Thierry
- Abstract
This study aimed to assess the safety and efficacy at midterm follow-up of left atrial appendage occlusion (LAAO) using different devices, in real life in Belgium. Between June 2009 and November 2016, 457 consecutive patients (63% male, 75±12 yrs, CHA2DS2-VASc 4±0.6, HAS-BLED 3.5±0.7) undergoing LAAO were included. Technical success was 97.1%. There were 19 periprocedural major adverse events (4.1%) including three deaths (0.6%), nine tamponades (1.9%), four major bleedings (0.8%) and two device embolisations (0.4%). Among patients successfully implanted having a complete follow-up (672 patient-years, median follow-up 370 days), the actual annual stroke rate was 1.2%, lower than the expected stroke risk of 4% (70% reduction). The observed bleeding rate was 2%, while the calculated risk was 3.7% (46% reduction). Kaplan-Meier analysis showed a similar overall survival (93±2% and 87±3% versus 91±3% and 87±4%; p=0.35) and event-free survival (92±2% and 84±3% versus 88±3% and 80±5%; p=0.17) at one and two years, for the ACP/Amulet versus the WATCHMAN groups of patients, respectively. The data from the Belgian left atrial appendage occlusion registry suggest that the procedure is effective and relatively safe in a real-world setting, using either the WATCHMAN or the ACP/Amulet device.
- Published
- 2018
45. Transcatheter left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation: Results from the Belgian registry
- Author
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Kefer, Joelle, Aminian, Adel, Vermeersch, Paul, De Potter, Tom, Stammen, Francis, Benit, Edouard, Budts, Werner, Missault, Luc, Drieghe, Benny, Buysschaert, Ian, Cornelis, Kristoff, Herzet, Jean Manuel, Guédès, Antoine, Debbas, Nadia, Rivero, Maximo, Lempereur, Mathieu, Lochy, Stijn, Casado Arroyo, Ruben, Laruelle, Christophe, Debruyne, Philippe, Ledent, Thierry, Kefer, Joelle, Aminian, Adel, Vermeersch, Paul, De Potter, Tom, Stammen, Francis, Benit, Edouard, Budts, Werner, Missault, Luc, Drieghe, Benny, Buysschaert, Ian, Cornelis, Kristoff, Herzet, Jean Manuel, Guédès, Antoine, Debbas, Nadia, Rivero, Maximo, Lempereur, Mathieu, Lochy, Stijn, Casado Arroyo, Ruben, Laruelle, Christophe, Debruyne, Philippe, and Ledent, Thierry
- Abstract
Aims: This study aimed to assess the safety and efficacy at midterm follow-up of left atrial appendage occlusion (LAAO) using different devices, in real life in Belgium. Methods and results: Between June 2009 and November 2016, 457 consecutive patients (63% male, 75±12 yrs, CHA2DS2-VASc 4±0.6, HAS-BLED 3.5±0.7) undergoing LAAO were included. Technical success was 97.1%. There were 19 periprocedural major adverse events (4.1%) including three deaths (0.6%), nine tamponades (1.9%), four major bleedings (0.8%) and two device embolisations (0.4%). Among patients successfully implanted having a complete follow-up (672 patient-years, median follow-up 370 days), the actual annual stroke rate was 1.2%, lower than the expected stroke risk of 4% (70% reduction). The observed bleeding rate was 2%, while the calculated risk was 3.7% (46% reduction). Kaplan- Meier analysis showed a similar overall survival (93±2% and 87±3% versus 91±3% and 87±4%; p=0.35) and event-free survival (92±2% and 84±3% versus 88±3% and 80±5%; p=0.17) at one and two years, for the ACP/Amulet versus the WATCHMAN groups of patients, respectively. Conclusions: The data from the Belgian left atrial appendage occlusion registry suggest that the procedure is effective and relatively safe in a real-world setting, using either the WATCHMAN or the ACP/Amulet device., SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2018
46. Optical Coherence Tomography Findings in Patients With Coronary Stent Thrombosis
- Author
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Adriaenssens, Tom, Joner, Michael, Godschalk, Thea C., Malik, Nikesh, Alfonso, Fernando, Xhepa, Erion, De Cock, Dries, Komukai, Kenichi, Tada, Tomohisa, Cuesta, Javier, Sirbu, Vasile, Feldman, Laurent J., Neumann, Franz-Josef, Goodall, Alison H., Heestermans, Ton, Buysschaert, Ian, Hlinomaz, Ota, Belmans, Ann, Desmet, Walter, ten Berg, Jurrien M., Gershlick, Anthony H., Massberg, Steffen, Kastrati, Adnan, Guagliumi, Giulio, and Byrne, Robert A.
- Subjects
ddc - Published
- 2017
47. Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial
- Author
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Vranckx, Pascal, primary, Valgimigli, Marco, additional, Jüni, Peter, additional, Hamm, Christian, additional, Steg, Philippe Gabriel, additional, Heg, Dik, additional, van Es, Gerrit Anne, additional, McFadden, Eugene P, additional, Onuma, Yoshinobu, additional, van Meijeren, Cokky, additional, Chichareon, Ply, additional, Benit, Edouard, additional, Möllmann, Helge, additional, Janssens, Luc, additional, Ferrario, Maurizio, additional, Moschovitis, Aris, additional, Zurakowski, Aleksander, additional, Dominici, Marcello, additional, Van Geuns, Robert Jan, additional, Huber, Kurt, additional, Slagboom, Ton, additional, Serruys, Patrick W, additional, Windecker, Stephan, additional, Abdellaoui, Mohamed, additional, Adlam, David, additional, Akin, Ibrahim, additional, Albarran Gonzalez-Trevilla, Agustin, additional, Almeida, Manuel, additional, Alves Lemos Neto, Pedro, additional, Aminian, Adel, additional, Anderson, Richard, additional, Andreae, Rick, additional, Angioi, Michael, additional, Asano, Taku, additional, Barbato, Emanuele, additional, Barlis, Peter, additional, Barraud, Pascal, additional, Bertrand, Olivier, additional, Beygui, Farzin, additional, Bolognese, Leonardo, additional, Botelho, Roberto, additional, Bouwman, Coby, additional, Bressers, Marco, additional, Brunel, Philippe, additional, Buszman, Pawel, additional, Buysschaert, Ian, additional, Canas da Silva, Pedro, additional, Carrie, Didier, additional, Cequier, Angel, additional, Chin Chang, Chun, additional, Chowdhary, Saqib, additional, Collet, Carlos, additional, Colombo, Antonio, additional, Cotton, James, additional, Cruz Ferreira, Rui, additional, Curello, Salvatore, additional, Curzen, Nick, additional, de Bot, Judith, additional, de Vreede, Tone, additional, Delle Karth, Georg, additional, Dijksma, Lynn, additional, Édes, István, additional, Eeckhout, Eric, additional, Eitel, Ingo, additional, Faluközy, József, additional, Fath-Ordoubadi, Farzin, additional, Fontos, Geza, additional, Francisco Diaz, Jose, additional, Freitas Quintella, Edgard, additional, Frey, Bernhard, additional, Friedrich, Guy, additional, Galasko, Gavin, additional, Galuszka, Grzegorz, additional, Gama Ribeiro, Vasco, additional, Garg, Scot, additional, Gargiulo, Giuseppe, additional, Geisler, Tobias, additional, Gelev, Valeri, additional, Ghandilyan, Art, additional, Goicolea, Javier, additional, Gori, Tommaso, additional, Gragnano, Felice, additional, Guimarães, Ana, additional, Haude, Michael, additional, Heijke, Pieter, additional, Hernández Antolin, Rosa Ana, additional, Hildick-Smith, David, additional, Hillen, Dorien, additional, Hoekman, Ina, additional, Hofma, Sjoerd, additional, Holmvang, Lene, additional, Hoole, Stephen, additional, Horváth, Iván, additional, Hugense, Annemarie, additional, Ibrahim, Karim, additional, Iñiguez, Andres, additional, Isaaz, Karl, additional, Jambrik, Zoltán, additional, Jasionowicz, Pawel, additional, Jonk, Judith, additional, Jung, Werner, additional, Katagiri, Yuki, additional, Kogame, Norihiro, additional, Koh, Tian Hai, additional, Koning, René, additional, Konteva, Mariana, additional, Kőszegi, Zsolt, additional, Krackhardt, Florian, additional, Kreuger, Yvonne, additional, Kukreja, Neville, additional, Ladan, Boudijn, additional, Lantelme, Pierre, additional, Leandro, Sergio, additional, Leibundgut, Gregor, additional, Liebetrau, Christoph, additional, Lindeboom, Wietze, additional, Macaya Miguel, Carlos, additional, Mach, François, additional, Magro, Michael, additional, Maillard, Luc, additional, Manavifar, Negar, additional, Mauri, Laura, additional, McFadden, Eugene, additional, Merkely, Bela, additional, Miyazaki, Yosuke, additional, Młodziankowski, Adam, additional, Moccetti, Tiziano, additional, Modolo, Rodrigo, additional, Möllman, Helge, additional, Morelle, Jean-François, additional, Munndt Ottesen, Michael, additional, Muurling, Martin, additional, Naber, Christoph Kurt, additional, Neumann, Franz-Josef, additional, Oldroyd, Keith, additional, Ong, Paul, additional, Palsrok, Sanne, additional, Petrov, Ivo, additional, Plante, Sylvain, additional, Prokopczuk, Janusz, additional, Rademaker-Havinga, Tessa, additional, Raffel, Christopher, additional, Rensing, Benno, additional, Roffi, Marco, additional, Royaards, Kees-Jan, additional, Sabate, Manel, additional, Schächinger, Volker, additional, Seidler, Tim, additional, Serra Peñaranda, Antonio, additional, Serruys, Patrick, additional, Sikarulidze, Lali, additional, Soliman, Osama I, additional, Sousa, Amanda, additional, Spitzer, Ernest, additional, Stables, Rod, additional, Steg, Gabriel, additional, Steinwender, Clemens, additional, Subkovas, Eduardas, additional, Suryapranata, Harry, additional, Takahashi, Kuniaki, additional, Talwar, Suneel, additional, Teiger, Emmanuel, additional, ter Weele, Addy, additional, Teurlings, Eva, additional, Thury, Attila, additional, Tijssen, Jan, additional, Tonev, Gincho, additional, Trendafilova-Lazarova, Diana, additional, Tumscitz, Carlo, additional, Umans, Victor, additional, Ungi, Imre, additional, Valkov, Veselin, additional, van der Harst, Pim, additional, van Geuns, Robert Jan, additional, Vassilev, Dobrin, additional, Velchev, Vasil, additional, Velthuizen, Esther, additional, Verheugt, Freek, additional, Vlcek, Natalia, additional, vom Dahl, Jürgen, additional, Vrolix, Mathias, additional, Walsh, Simon, additional, Werner, Nikos, additional, Witsenburg, Maarten, additional, Zaman, Azfar, additional, Żmudka, Krzysztof, additional, Zrenner, Bernhard, additional, and Zweiker, Robert, additional
- Published
- 2018
- Full Text
- View/download PDF
48. Transcatheter left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation: results from the Belgian registry
- Author
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Kefer, Joelle, primary, Aminian, Adel, additional, Vermeersch, Paul, additional, de Potter, Tom, additional, Stammen, Francis, additional, Benit, Edouard, additional, Budts, Werner, additional, Missault, Luc, additional, Drieghe, Benny, additional, Buysschaert, Ian, additional, Cornelis, Kristoff, additional, Herzet, Jean-Manuel, additional, Guedes, Antoine, additional, Debbas, Nadia, additional, Rivero, Maximo, additional, Lempereur, Mathieu, additional, Lochy, Stijn, additional, Casado-Arroyo, Ruben, additional, Laruelle, Christophe, additional, Debruyne, Philippe, additional, and Ledent, Thierry, additional
- Published
- 2018
- Full Text
- View/download PDF
49. Complications of pulmonary vein isolation in atrial fibrillation: predictors and comparison between four different ablation techniques: Results from the MIddelheim PVI-registry
- Author
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De Greef, Yves, primary, Ströker, Edwin, additional, Schwagten, Bruno, additional, Kupics, Kaspars, additional, De Cocker, Jeroen, additional, Chierchia, Gian-Battista, additional, de Asmundis, Carlo, additional, Stockman, Dirk, additional, and Buysschaert, Ian, additional
- Published
- 2017
- Full Text
- View/download PDF
50. Very late stent thrombosis and longitudinal stent deformation
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Buysschaert, Ian, primary, Ughi, Giovanni J., additional, Adriaenssens, Tom, additional, and Vermeersch, Paul, additional
- Published
- 2017
- Full Text
- View/download PDF
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