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4. Design and experimental study of superconducting left-handed transmission lines with tunable dispersion

Author

Ovchinnikova, E. A., Butz, S., Jung, P., Koshelets, V. P., Filippenko, L. V., Averkin, A. S., Shitov, S. V., and Ustinov, A. V.

Subjects
Condensed Matter - Superconductivity
Abstract

We study microwave properties of a superconducting tunable coplanar waveguide (CPW). Pairs of Josephson junctions are forming superconducting quantum interference devices (SQUIDs), which shunt the central conductor of the CPW. The Josephson inductance of the SQUIDs is varied in the range of 0.08-0.5 nH by applying an external dc magnetic field. The central conductor of the CPW contains Josephson junctions connected in series that provide extra inductances; the magnetic field controlling the SQUIDs is weak enough not to influence the inductance of the chain of the single junctions. The circuit is designed to have left- and right-handed transmission properties separated by a variable rejection band; the band edges can be tuned by the magnetic field. We present transmission measurements on CPWs based on up to 120 Nb-AlOx-Nb Josephson junctions. At zero magnetic field, we observed no rejection band in the frequency range of 8-11 GHz. When applying the magnetic field, a rejection band between 7 GHz and 9 GHz appears. The experimental data are compared with numerical simulations., Comment: 8 pages, 8 figures

Published
2013
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5. Protecting SQUID metamaterials against stray magnetic field

Author

Butz, S., Jung, P., Filippenko, L. V., Koshelets, V. P., and Ustinov, A. V.

Subjects
Condensed Matter - Superconductivity
Abstract

Using superconducting quantum interference devices (SQUIDs) as basic, low-loss elements of thin-film metamaterials has one main advantage: Their resonance frequency is easily tunable by applying a weak magnetic field. The downside, however, is a strong sensitivity to stray and inhomogeneous magnetic fields. In this work, we demonstrate that even small magnetic fields from electronic components destroy the collective, resonant behaviour of the SQUID metamaterial. We also show how the effect of these fields can be minimized. As a first step, magnetic shielding decreases any initially present fields including the earth's magnetic field. However, further measures like improvements in the sample geometry have to be taken to avoid the trapping of Abrikosov vortices.

Published
2013
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6. A one-dimensional tunable magnetic metamaterial

Author

Butz, S., Jung, P., Filippenko, L. V., Koshelets, V. P., and Ustinov, A. V.

Subjects
Condensed Matter - Superconductivity
Abstract

We present experimental data on a one-dimensional superconducting metamaterial that is tunable over a broad frequency band. The basic building block of this magnetic thin-film medium is a single-junction (rf-) superconducting quantum interference device (SQUID). Due to the nonlinear inductance of such an element, its resonance frequency is tunable in situ by applying a dc magnetic field. We demonstrate that this results in tunable effective parameters of our metamaterial consisting of 54 SQUIDs. In order to obtain the effective magnetic permeability from the measured data, we employ a technique that uses only the complex transmission coefficient S21.

Published
2013
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18. Bedeutung von Endothelial Cell-Selective Adhesion Molecule (ESAM) für die Leukozytenmigration und die vaskuläre Permeabilität bei hepatischer Ischämie-Reperfusion

Author

Khandoga, A., Hüttinger, S., Khandoga, A. -G., Butz, S., Jauch, K. -W., Vestweber, D., Krombach, F., Buhr, H. J., editor, Hölscher, A., editor, Izbicki, J. R., editor, Jauch, K. W., editor, Post, S., editor, Allgayer, H., editor, Bartsch, D. K., editor, Fries, H., editor, Ghadimi, B. M., editor, Habermann, J. K., editor, Kalthoff, H., editor, Schackert, H. K., editor, Bruns, C. J., editor, Duda, D. N., editor, Fändrich, F., editor, Heberer, M., editor, Nüssler, A. K., editor, Stark, G. B., editor, Brückner, U. B., editor, Ertel, W., editor, Faist, E., editor, Heidecke, C. D., editor, Kalff, J. C., editor, Menger, M. D., editor, Schade, U. F., editor, Vollmar, B., editor, Bechstein, W. O., editor, Klar, E., editor, Klempnauer, J., editor, Minor, T., editor, Neuhaus, P., editor, Schmidt, J., editor, Langer, S., editor, Laschke, M. W., editor, Machens, H. G., editor, Steinau, H. U., editor, Südkamp, N., editor, Vogt, P., editor, Berger, D., editor, Klinge, U., editor, Schachtrupp, A., editor, Schilling, M. K., editor, Schumpelick, V., editor, Altendorf-Hofmann, A., editor, Bollschweiler, E., editor, Bruch, H. -P., editor, Lehnert, T., editor, Lorenz, W., editor, Neugebauer, E., editor, Ohmann, C., editor, Seiler, C. M., editor, Becker, H., editor, Betzler, M., editor, Bittner, R., editor, Broelsch, C., editor, Büchler, M. W., editor, Bumm, R., editor, Dralle, H., editor, Friess, H., editor, Frilling, A., editor, Germer, C. T., editor, Hopt, U., editor, Jonas, S., editor, Jost, J., editor, Markus, B., editor, Raab, H. R., editor, Reith, H. B., editor, Schlag, P. M., editor, Teichmann, W., editor, Uhl, W., editor, Wenisch, H., editor, and Zornig, C., editor

Published
2009
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24. Screening of 265 pesticides in water by thin-layer chromatography with automated multiple development

Author

Butz, S. and Stan, H.-J.

Subjects
Pesticides -- Research, Chromatographic analysis -- Research, Water -- Pesticide content, Chemistry
Abstract

High-performance thin-layer chromatography with automated multiple development (AMD-HPTLC) was used to screen water samples for pesticides. A universal gradient based on dichloromethane was employed to check for the presence of pesticides from different classes such as phenylureas, carbamates, triazines, phenoxycarboxylic acids, and others. In total, 283 pesticides were analyzed applying this gradient. The data for migration distances, the UV spectra, and the instrumental detection limits were compiled. Eighteen pesticides show an instrumental detection limit of more than 100 ng applied and can therefore not be analyzed from 1 L drinking water samples with AMD-HPTLC without further treatment. One liter drinking water samples were extracted by means of solid-phase extraction using RP-C18 material or liquid/liquid extraction with dichloromethane and screened with the universal gradient. The confirmation of suspect positive pesticide residues was performed with a second analysis applying special gradients optimized for the individual pesticide classes. Two examples of drinking water spiked at the 100 ng/L level are presented to demonstrate the merits of the method. In the first sample, the two triazine herbicides cyanazine and atrazine, forming a critical pair with identical reflectance spectra, were separated in a confirmatory run applying a smoother gradient. In the second sample, acidic herbicides were unsatisfactorily resolved with the universal gradient but were separated with a confirmatory gradient of different composition, allowing easy identification of picloram, acifluorfen, haloxyfop acid, and MCPA.

Published
1995

31. Wann sind 'Tailored Interventions' zur Leitlinienimplementierung erfolgreich? Ein systematischer Review von randomisierten kontrollierten Studien

Author

Butz, S, Hoffmann-Eßer, W, Althaus, A, Muche-Borowski, C, Scherer, M, Siering, U, and Lühmann, D

Subjects
tailored interventions, ddc: 610, Leitlinienimplementierung, 610 Medical sciences, Medicine
Abstract

Hintergrund: Evidenzbasierte Leitlinien sind ein Instrument für den Transfer komplexer Forschungsergebnisse in die Praxis. Bei adäquater Umsetzung ihrer Empfehlungen soll eine Verbesserung der Versorgung erzielt werden. Aktuell wird angenommen, dass eine Leitlinienimplementierung umso erfolgreicher[zum vollständigen Text gelangen Sie über die oben angegebene URL], 50. Kongress für Allgemeinmedizin und Familienmedizin

Published
2016
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34. Effektivität von Interventionen zur Leitlinienimplementierung: Ein Review of Reviews

Author

Butz, S, Hoffmann-Eßer, W, Althaus, A, Muche-Borowski, C, Lühmann, D, Scherer, M, and Siering, U

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Evidenzbasierte Leitlinien stellen ein Instrument für den Transfer komplexer Forschungsergebnisse in die klinische Praxis dar. Bei adäquater Umsetzung ihrer Empfehlungen soll eine Verbesserung der Versorgung erzielt werden. Die erfolgreiche Umsetzung setzt jedoch eine zielführende[zum vollständigen Text gelangen Sie über die oben angegebene URL], Gemeinsam informiert entscheiden; 17. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin

Published
2016
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35. Wann sind 'Tailored Interventions' zur Leitlinienimplementierung erfolgreich? Ein Review von kontrollierten Studien

Author

Butz, S, Hoffmann-Eßer, W, Althaus, A, Muche-Borowski, C, Scherer, M, Siering, U, and Lühmann, D

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Evidenzbasierte Leitlinien sind ein Instrument für den Transfer komplexer Forschungsergebnisse in die klinische Praxis. Bei adäquater Umsetzung ihrer Empfehlungen soll eine Verbesserung der Versorgung erzielt werden. Der Umsetzungserfolg kann durch verschiedene hinderliche und[zum vollständigen Text gelangen Sie über die oben angegebene URL], Gemeinsam informiert entscheiden; 17. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin

Published
2016
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36. Urinary cGMP excretion after hormone replacement therapy in postmenopausal women

Author

Teichmann At, Harald Seeger, Theodor H. Lippert, Kasspohl-Butz S, and Alfred O. Mueck

Subjects
medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Urinary system, medicine.medical_treatment, Administration, Oral, Urine, Excretion, Endocrinology, Internal medicine, Internal Medicine, medicine, Humans, Cyclic GMP, Cross-Over Studies, Estrogens, Conjugated (USP), Estradiol, business.industry, Estrogen Replacement Therapy, Estradiol valerate, Hormone replacement therapy (menopause), General Medicine, Middle Aged, Norethisterone acetate, Postmenopause, Norethindrone Acetate, Treatment Outcome, Female, Norethindrone, medicine.symptom, business, Vasoconstriction, Hormone, medicine.drug
Abstract

It is well established that estrogens and progestogens are able to influence the vasotonus in postmenopausal women. The present study was undertaken to find out if the NO/cGMP-system is involved in this hormone action. Urinary cGMP excretion which can reflect intracellular cGMP production elicited by NO (EDRF) was investigated in 20 postmenopausal women. In an open cross-over study design norethisterone acetate was administered orally for 8 days, estradiol valerate orally for 9 days and a combination of both substances for 12 days. After all three treatment phases urinary cGMP expressed as percentage of the pretreatment value was increased at a statistically significant level. Due to high individual variations no significant differences could be found among the values after the three treatment phases. It was concluded that the NO/cGMP-system may play a role in maintaining vasotonus in postmenopausal women under hormone replacement therapy.

Published
2009
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45. Berücksichtigen Leitlinien unpublizierte Daten? Eine Analyse aktueller evidenzbasierter Leitlinien

Author

Hoffmann-Eßer, W, Butz, S, Becker, M, Ernsting, C, Eikermann, M, Lühmann, D, Muche-Borowski, C, Ein Waldt, S, Scherer, M, Rüther, A, and Siering, U

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die Berücksichtigung unpublizierter Studiendaten kann die Ergebnisse systematischer Übersichten erheblich verändern. Vor diesem Hintergrund stellt sich die Frage, inwieweit evidenzbasierte Leitlinien den Umgang mit unpublizierten Daten thematisieren. Fragestellung: Enthalten[for full text, please go to the a.m. URL], Prävention zwischen Evidenz und Eminenz; 15. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin

Published
2014
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46. Ist das Disease-Management-Programm COPD aktuell? – Eine Untersuchung auf Basis aktueller evidenzbasierter Leitlinien

Author

Ein Waldt, S, Hoffmann-Eßer, W, Butz, S, Lühmann, D, Holzmann, N, Muche-Borowski, C, Yurdakul, A, Scherer, M, Siering, U, and Rüther, A

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Empfehlungen evidenzbasierter Leitlinien zu Versorgungsaspekten einer Erkrankung gelten als Versorgungsstandards. Sie werden in Leitliniensynopsen des Instituts für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) zusammengefasst und zur Prüfung eines Überarbeitungsbedarfs[for full text, please go to the a.m. URL], Prävention zwischen Evidenz und Eminenz; 15. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin

Published
2014
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47. Erratum: A one-dimensional tunable magnetic metamaterial (Optics Express)

Author

Butz, S., Jung, P., Filippenko, L. V., Koshelets, V. P., and Ustinov, A. V.

Subjects
Physics, ddc:530
Abstract

We have detected an error in our data retrieval script which prepares the measured transmission data for the conversion to magnetic permeability. Correcting this error requires modification of Fig. 4(b) and Fig. 5 in the original publication. All methods, calculations and the conclusion in the published paper are still correct.

Published
2014
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48. Influence of Norethisterone Acetate and Estradiol on the Serotonin Metabolism of Postmenopausal Women

Author

Theodor H. Lippert, Teichmann At, Kasspohl-Butz S, Harald Seeger, and Alfred O. Mueck

Subjects
Serotonin, medicine.medical_specialty, medicine.drug_class, Endocrinology, Diabetes and Metabolism, Metabolite, Clinical Biochemistry, Biochemistry, chemistry.chemical_compound, Endocrinology, Internal medicine, medicine, Humans, Estradiol, Estrogen Replacement Therapy, Biochemistry (medical), Estradiol valerate, General Medicine, Hydroxyindoleacetic Acid, Middle Aged, Norethisterone acetate, Postmenopause, Norethindrone Acetate, chemistry, Estrogen, Female, Serotonin Production, Norethindrone, Progestin, hormones, hormone substitutes, and hormone antagonists, Hormone, medicine.drug
Abstract

Previous studies have shown that estradiol increases urinary excretion of the main stable metabolite of serotonin, 5-hydroxyindole acetic acid (5-HIAA), reflecting an increase in serotonin production. In the present study, the effect of the progestin norethisterone acetate (NETA) on serotonin metabolism was investigated, both alone and in addition to estradiol replacement in 20 postmenopausal women. Urinary excretion of 5-HIAA was measured after treatment with NETA orally for 8 days, estradiol valerate orally for 9 days and a combination of both hormones for 12 days. 5-HIAA values, expressed as percentages of the pretreatment values, were significantly increased only after the estrogen treatment phase. NETA alone did not significantly alter the serotonin metabolite excretion; in combination with estradiol, the estradiol effect on serotonin metabolism was abolished. This indicates that adding norethisterone acetate to estradiol replacement therapy may have a negative impact on the effect of estradiol on serotonin metabolism.

Published
1997
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49. Medical specialist attendance in nursing homes

Author

Balzer, K, Butz, S, Bentzel, J, Boulkhemair, D, and Lühmann, D

Subjects
alte Menschen, Pflegeheime, GESUNDHEITSVERSORGUNG, INTEGRIERTE, DEUTSCHLAND, 610 Medical sciences, Medicine, nursing homes, medizinische Grundversorgung, KRANKENPFLEGEHEIME, Article, primary health care, aged, delivery of health care, integrated, ddc: 610, Germany
Abstract

The care in nursing homes was examined based on scientific studies. The analysis focuses on dementia and type II diabetes. There is evidence for deficits in the supply of medical specialist attendance to nursing home residents with these diseases in Germany. Compared with corresponding guidelines the medical care for nursing home residents may be too low or inadequate., GMS Health Technology Assessment; 9:Doc02; ISSN 1861-8863

Published
2013

50. Modellprojekte zur Verbesserung der fachärztlichen Versorgung von Pflegeheimbewohnern: eine Bestandsaufnahme

Author

Butz, S, Balzer, K, Bentzel, J, Boulkhemair, D, and Lühmann, D

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Mehrere Studien [ref:1], [ref:2] dokumentieren, dass Bewohner von Pflegeeinrichtungen weniger fachärztliche Versorgung in Anspruch nehmen als angesichts ihrer Morbidität zu erwarten wäre. Seither wurde in einer Anzahl von Studien und Modellprojekten versucht,[for full text, please go to the a.m. URL], Entscheiden trotz Unsicherheit; 14. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin

Published
2013
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