Search

Your search keyword '"Butin, Marine"' showing total 190 results
Start Over Author "Butin, Marine"
190 results on '"Butin, Marine"'

2. Clinical Chorioamnionitis and Neurodevelopment at 5 Years of Age in Children Born Preterm: The EPIPAGE-2 Cohort Study

Author

Boileau, Pascal, Butin, Marine, Gras-Le Guen, Christèle, Kuhn, Pierre, Letouzey, Mathilde, Mitha, Ayoub, Torchin, Héloïse, Charlier, Caroline, Salmon, Fanny, Kayem, Gilles, Maisonneuve, Emeline, Foix-L’Hélias, Laurence, Benhammou, Valérie, Kaminski, Monique, Marchand-Martin, Laetitia, Kana, Gildas, Subtil, Damien, Lorthe, Elsa, and Ancel, Pierre-Yves

Published
2024
Full Text
View/download PDF

10. Clinical Chorioamnionitis and Neurodevelopment at 5 Years of Age in Children Born Preterm: The EPIPAGE-2 Cohort Study

Author

Salmon RM, Fanny, primary, Kayem, Gilles, additional, Maisonneuve, Emeline, additional, Foix-L’Hélias, Laurence, additional, Benhammou, Valérie, additional, Kaminski, Monique, additional, Marchand-Martin, Laetitia, additional, Kana, Gildas, additional, Subtil, Damien, additional, Lorthe RM, Elsa, additional, Ancel, Pierre-Yves, additional, Letouzey, Mathilde, additional, Boileau, Pascal, additional, Butin, Marine, additional, Gras-Le Guen, Christèle, additional, Kuhn, Pierre, additional, Lorthe, Elsa, additional, Mitha, Ayoub, additional, Torchin, Héloïse, additional, and Charlier, Caroline, additional

Published
2024
Full Text
View/download PDF

13. Impact of a nurse education programme on oral feeding in a neonatal unit.

Author

Beissel, Anne, Denis, Angélique, Laborie, Sophie, Pillet, Fabienne, Gauthier‐Moulinier, Hélène, Hommey, Sophie, Tume, Lyvonne N., Butin, Marine, and Touzet, Sandrine

Subjects
NEONATOLOGISTS, PEDIATRIC nurses, PARENTS, INTENSIVE care nursing, ACADEMIC medical centers, RESEARCH funding, NEONATAL intensive care units, EDUCATIONAL outcomes, LOGISTIC regression analysis, FISHER exact test, NEONATAL intensive care, NURSING interventions, DESCRIPTIVE statistics, NURSING, INFANT nutrition, PRE-tests & post-tests, INTUBATION, KAPLAN-Meier estimator, ONE-way analysis of variance, NEONATAL nursing, LENGTH of stay in hospitals, COMPARATIVE studies, SURVIVAL analysis (Biometry), CONFIDENCE intervals, QUALITY assurance, CRITICAL care nurses, PROPORTIONAL hazards models, REGRESSION analysis
Abstract

Background: Premature neonates often experience feeding difficulties during their hospital stay, and evidence‐based interventions have been shown to improve feeding outcomes. Aim: This study investigated whether an infant‐cue based nurse educational feeding bundle accelerates the achievement of independent oral feeding in neonates in a neonatal intensive care unit. Study Design: A quality improvement study with a pre, during and post intervention test design. All premature neonates admitted to the unit were eligible. The feeding programme included a four‐month nurse training module and nurse coaching. Results: A hundred and twenty‐five nurses or nurse assistants attended the programme and 706 neonates were included. The median time to independent oral feeding (IOF) was 40, 36 and 37 days, respectively, for pre, during and post intervention. The reduction in time to IOF observed during the post‐intervention period compared with the baseline period was significant (HR = 1.32, CI 95%: 1.01–1.74). No difference was noted in the length of hospital stay between the three study periods. Conclusions: An infant‐cue based nurse educational feeding bundle can promote earlier achievement of IOF in preterm neonates. Relevance to Clinical Practice: This quality improvement study demonstrates the impact that a nurse‐driven intervention in neonatal care can have on improving practice. Feeding interventions involve the early introduction of oral feeding, non‐nutritive sucking (NNS), and oral motor stimulation, and should be individualized for each neonate. These individualized feeding interventions applied by all nurses and assistant nurses, can facilitate the achievement of earlier independent oral feeding in preterm infants and should be included in neonatal critical care nurse education programs. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

17. Performance of 11 Host Biomarkers Alone or in Combination in the Diagnosis of Late-Onset Sepsis in Hospitalized Neonates: The Prospective EMERAUDE Study

Author

Pons, Sylvie, primary, Trouillet-Assant, Sophie, additional, Subtil, Fabien, additional, Abbas-Chorfa, Fatima, additional, Cornaton, Elise, additional, Berthiot, Amélie, additional, Galletti, Sonia, additional, Plat, Aurélie, additional, Rapin, Stephanie, additional, Trapes, Laurene, additional, Generenaz, Laurence, additional, Brengel-Pesce, Karen, additional, Callies, Arnaud, additional, Plaisant, Franck, additional, Claris, Olivier, additional, Portefaix, Aurelie, additional, Flamant, Cyril, additional, and Butin, Marine, additional

Published
2023
Full Text
View/download PDF

25. Performance of 11 host biomarkers alone or in combination in the diagnosis of late-onset sepsis in hospitalized neonates: the prospective EMERAUDE study

Author

Pons, Sylvie, primary, Trouillet-Assant, Sophie, additional, Subtil, Fabien, additional, Abbas-Chorfa, Fatima, additional, Cornaton, Elise, additional, Berthiot, Amélie, additional, Galletti, Sonia, additional, Plat, Aurelie, additional, Rapin, Stephanie, additional, Trapes, Laurene, additional, Generenaz, Laurence, additional, Brengel-Pesce, Karen, additional, Callies, Arnaud, additional, Plaisant, Franck, additional, Claris, Olivier, additional, Portefaix, Aurelie, additional, Flamant, Cyril, additional, and Butin, Marine, additional

Published
2022
Full Text
View/download PDF

27. Changement de dispositif de perfusion dans un service de néonatologie : impact sur les infections et la satisfaction des soignants

Author

Larue, Victoria, Barreto, Christine, Barbeau, Pauline, Constant, Hélène, Plaisant, Franck, and Butin, Marine

Subjects
Surveillance des infections, Infection associée aux soins, Dispositif médical, Néonatologie, Infection du cathéter
Abstract

Contexte et objectifs. En réanimation néonatale, les patients ont souvent besoin d’un accès veineux de type cathéter veineux central (CVC). Ce CVC est à risque de complications et, notamment, d’infections liées au cathéter. Un nouveau dispositif de perfusion, conçu pour la néonatologie, a été mis en place en avril 2019 dans notre hôpital. L’objectif principal était d’évaluer l’impact de ce nouveau dispositif en réanimation néonatale sur le risque infectieux. L’objectif secondaire était d’évaluer la satisfaction des soignants concernant son utilisation. Méthode. Une étude rétrospective a été menée sur les données de janvier 2018 à février 2019 (ancien montage : système Octopus®, Vygon) et de mai 2019 à juin 2020 (nouveau montage sur mesure avec valves NanoClaveTM, ICU Medical). Les densités d’incidence d’infections liées au cathéter de chaque période ont été comparées. L’ergonomie d’utilisation a été évaluée par un questionnaire auprès des 120 infirmiers du service. Résultats. Durant la première période, 434 patients étaient porteurs d’au moins un CVC, contre 413 pendant la seconde. Les populations étaient comparables à la naissance pour l’âge gestationnel et le poids. Le nombre de cathéters était respectivement de 662 et 684 et le taux d’incidence d’infections liées au cathéter de 8,6 et 9,1 pour 100 cathéters. Les densités d’incidence d’infections liées au cathéter n’étaient pas significativement différentes (8,2 vs 8,9 pour 1 000 jours-cathéter ; p=0,75). Les 62 infirmiers qui ont complété le questionnaire étaient tous satisfaits ou très satisfaits du dispositif. Conclusions. L’utilisation du nouveau dispositif de perfusion n’a pas permis de diminuer le taux d’infection mais il est apprécié par l’équipe soignante sans présenter de surrisque d’infection.

Published
2023
Full Text
View/download PDF

29. Risk Factors of Very Severe RSV Infections in a Multicenter Cohort of Very Preterm and Extreme Preterm Babies Receiving or Not Palivizumab

Author

Mulot, Gwenaelle, Benchaib, Mehdi, Plaisant, Frank, Ploin, Dominique, Gillet, Yves, Javouhey, Etienne, Claris, Olivier, Picaud, Jean-Charles, Casalegno, Jean-Sebastien, Butin, Marine, Hôpital Femme Mère Enfant [CHU - HCL] (HFME), Hospices Civils de Lyon (HCL), Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service de Radiologie [Hôpital Femme Mère Enfant - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Université de Lyon, Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), and Hôpital de la Croix-Rousse [CHU - HCL]

Subjects
LRTI, [SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics, palivizumab, Pediatrics, Perinatology and Child Health, cohort study, RSV, bronchiolitis, preterm
Abstract

IntroductionPreterm infants are at risk of lower respiratory tract infections (LRTI), including Respiratory Syncytial Virus (RSV) associated bronchiolitis, for which palivizumab prophylaxis can be proposed. Our aim was to determine risk factors of very severe RSV disease in children born before 34 weeks of gestation.MethodsAmong 2,101 infants born before 34 weeks of gestation in 3 maternity wards between 2012 and 2017, the laboratory confirmed RSV-infected patients requiring hospitalization before 12 months of corrected age were retrospectively included. We collected data about the neonatal period, the palivizumab prophylaxis and the hospitalization for a RSV-related LRTI. LRTI was considered as very severe (VS-LRTI) when patients required invasive or non-invasive positive pressure ventilation.ResultsAmong 86 included patients, 31 met the criteria of VS-LRTI. The VS-LRTI patients had a higher birth gestational age and weight but less heart disease and bronchopulmonary dysplasia. They received palivizumab prophylaxis less frequently than the other patients but the difference was not significant. At the onset of infection, VS-LRTI patients had a younger corrected age for prematurity and presented more frequently with apnea, bradycardia, life-threatening event, hemodynamic failure, hypercapnia. Using logistic regression, the main factor associated with VS-LRTI was a younger corrected age for prematurity at the onset of infection [Odd ratio for each month of corrected age = 0.77 (0.62; 0.93), p = 0.012].ConclusionInfants at the highest risk of VS-LRTI were infants with a younger corrected age for prematurity. Therefore, a better targeting of infants requiring palivizumab prophylaxis and early interventions at hospital discharge could limit VS-LRTI in these infants.

Published
2022

32. Early Antibiotic Exposure and Adverse Outcomes in Very Preterm Infants at Low Risk of Early-Onset Sepsis: The EPIPAGE-2 Cohort Study

Author

Letouzey, Mathilde, primary, Lorthe, Elsa, additional, Marchand-Martin, Laetitia, additional, Kayem, Gilles, additional, Charlier, Caroline, additional, Butin, Marine, additional, Mitha, Ayoub, additional, Kaminski, Monique, additional, Benhammou, Valerie, additional, Ancel, Pierre-Yves, additional, Boileau, Pascal, additional, Foix-L'Hélias, Laurence, additional, Gras-Le Guen, Christèle, additional, Kuhn, Pierre, additional, Letouzey, Mathilde, additional, Maisonneuve, Emeline, additional, Sibiude, Jeanne, additional, and Torchin, Héloïse, additional

Published
2022
Full Text
View/download PDF

33. Identifying the target population for primary Respiratory Syncytial Virus two-step prevention in infants: Normative Outcome of Hospitalisation Assessment for Newborns (NOHAN)

Author

Jourdain, Marine, primary, Benchaib, Mehdi, additional, Ploin, Dominique, additional, Gillet, Yves, additional, Javouhey, Etienne, additional, Horvat, Côme, additional, Massoud, Mona, additional, Butin, Marine, additional, Claris, Olivier, additional, Lina, Bruno, additional, and Casalegno, Jean-Sebastien, additional

Published
2022
Full Text
View/download PDF

35. Heterogeneous vancomycin resistance in Staphylococcus aureus does not predict development of vancomycin resistance upon vancomycin pressure

Author

Gaillard, Tiphaine, primary, Dupieux-Chabert, Céline, additional, Butin, Marine, additional, Dumitrescu, Oana, additional, Naceur, Oilida, additional, Bouveyron, Caroline, additional, Martra, Annie, additional, Bes, Michèle, additional, Tristan, Anne, additional, Vandenesch, François, additional, Lina, Gérard, additional, Laurent, Frédéric, additional, and Rasigade, Jean-Philippe, additional

Published
2022
Full Text
View/download PDF

36. Fetal growth restriction: underdiagnosed condition with non-optimal screening.

Author

Atallah, Anthony, Butin, Marine, Moret, Stéphanie, Claris, Olivier, Gaucherand, Pascal, and Doret-Dion, Muriel

Subjects
*FETAL growth retardation, *MEDICAL screening, *SMALL for gestational age, *FETAL monitoring, *PRENATAL diagnosis
Abstract

Background Fetal Growth restriction (FGR) is the pathological failure of a fetus to reach its biologically determined growth potential. Detection of FGR fetuses is a universally agreed key objective of antenatal care. Antenatal detection of FGR has undeniable benefits, juggling between intensive fetal surveillance and optimized timing of delivery; it reduces adverse perinatal outcomes by up to four-fold. However, FGR is still widely underdiagnosed. We aimed to identify the prevalence of FGR diagnosis in our wards and study the impact of the 2013 published French guidelines on the detection rate of FGR. The secondary objective aimed to highlight the factors of suboptimal screening in the population of non-diagnosed FGR fetuses and emphasize the screening method that led to antenatal diagnosis of FGR. Materials and methods We conducted a retrospective study at a single tertiary maternity center in Lyon-France, the Femme Mère Enfant Hospital, including the exhaustive population of FGR born after 24 + 0 weeks of gestation from 1 January 2011 to 31 December 2017. FGR was defined combining the neonatal and antenatal consensus-based definitions for early and late FGR in absence of congenital anomalies, excluding small for gestational age fetuses. For all FGR fetuses, we compared the antenatal detection rate of FGR during 2011–2013 to 2015–2017, since the French guidelines were published in December 2013. When FGR fetuses underwent an antenatal diagnosis of FGR, we retrospectively collected the characteristics that led to the diagnosis. When fetuses were not diagnosed as FGR, we retrospectively reviewed the implementation of the recommended screening method, enabling to evaluate whether screening was optimal or not. Statistical analysis was performed in July 2018, and statistical significance was regarded as a p-value <.05. Results Over the seven-year period, and among 31,052 newborns, 1020 (3.3%) infants were identified as FGR and met the inclusion criteria. The detection rate of FGR was similar before and after publication of the French Guidelines related to FGR in 2013. Indeed, 50.8% (201/395) FGR were diagnosed between 2011 and 2013 versus 52.6% (245/465) between 2015 and 2017 (p = .59). In the population of non-diagnosed FGR infants, screening was suboptimal in 80%. Symphysis-fundal height (SFH) was not measured in 10.7%, with no difference before and after 2014 (7.3 versus 11.8% p = .11). Ultrasound examination for fetal biometry had not been prescribed in spite of abnormal SFH in 47.7% of undiagnosed FGR infants. Diagnosis has been missed in 11.5% of infants because of misinterpretation of the estimated fetal weight’s centile. Conclusion FGR is widely underdiagnosed. However, the limited performances can partially be explained by the regular misuse of screening method in clinical practice. Despite the systematic third trimester ultrasound screening, the detection rate of FGR was similar to the one reported in the medical literature. The timing of routine third trimester ultrasound in low-risk women may be rethought. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

38. Low levels of respiratory syncytial virus activity in Europe during the 2020/21 season: what can we expect in the coming summer and autumn/winter?

Author

van Summeren, Jojanneke, Meijer, Adam, Aspelund, Guðrún, Casalegno, Jean Sebastien, Erna, Guðrún, Hoang, Uy, Lina, Bruno, de Lusignan, Simon, Teirlinck, Anne C., Thors, Valtýr, Paget, John, Ouziel, Antoine, Tardy, Jean-claude, Gaucherand, Pascal, Massardier, Jerome, Polazzi, Stephanie, Duclos, Antoine, Benchaib, Mehdi, Cartier, Regine, Jourdain, Marine, Ottmann, Michelle, Kramer, Rolf, Fiorini, Sylvie, Rivat, Nathalie, Mekki, Yahia, Fort-Jacquier, Julie, Barral, Maud-Catherine, Noelie, Vey, Haesebaert, Julie, Horvat, Come, Vidoni, Leo, Reynes, Jean-Marc, Eleouet, Jean-Francois, Josset, Laurence, Receveur, Matthieu, Javouhey, Etienne, Ploin, Dominique, Valette, Martine, Fanget, Remi, Targe, Sandrine Couray, Myar-Dury, Anne-Florence, Doret-Dion, Muriel, Massoud, Mona, Masson, Elsa, Bard, Emilie, Queromes, Gregory, Vanhems, Phillipe, Claris, Olivier, Butin, Marine, Ader, Florence, Bin, Sylvie, Gaymard, Alexandre, Morfin, Florence, Gillet, Yves, Netherlands Institute for Health Services Research [Utrecht] (NIVEL), National Institute for Public Health and the Environment [Bilthoven] (RIVM), Directorate of Health [Reykjavík], Institut des Agents Infectieux [Lyon] (IAI), Hospices Civils de Lyon (HCL), Landspitali National University Hospital of Iceland, University of Oxford [Oxford], Children’s Hospital [Reykjavik, Iceland], University of Iceland [Reykjavik], This study is performed as a side project of the RSV ComNet study. The aim of the RSV ComNet project is to measure the disease burden of RSV in children aged ≤5 years in primary care, and is funded by Sanofi Pasteur and AstraZeneca., VRS study group in Lyon: Antoine Ouziel, Jean-claude Tardy, Pascal Gaucherand, Jerome Massardier, Stephanie Polazzi, Antoine Duclos, Mehdi Benchaib, Regine Cartier, Marine Jourdain, Michelle Ottmann, Rolf Kramer, Sylvie Fiorini, Nathalie Rivat, Yahia Mekki, Julie Fort-Jacquier, Maud-Catherine Barral, Vey Noelie, Julie Haesebaert, Come Horvat, Leo Vidoni, Jean-Marc Reynes, Jean-Francois Eleouet, Laurence Josset, Matthieu Receveur, Etienne Javouhey, Dominique Ploin, Martine Valette, Remi Fanget, Sandrine Couray Targe, Anne-Florence Myar-Dury, Muriel Doret-Dion, Mona Massoud, Elsa Masson, Emilie Bard, Gregory Queromes, Phillipe Vanhems, Olivier Claris, Marine Butin, Florence Ader, Sylvie Bin, Alexandre Gaymard, Florence Morfin, Yves Gillet, and Lyon, VRS study group in

Subjects
Author's Correction, 0301 basic medicine, Veterinary medicine, viruses, Iceland, surveillance data, MESH: Respiratory Syncytial Virus, Human, Respiratory syncytial virus, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Child, Epidemiology, MESH: COVID-19, 030212 general & internal medicine, Respiratory system, Child, virus diseases, RSV, respiratory system, MESH: Iceland, MESH: Infant, Europe, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, epidemiology, France, Seasons, Winter season, Rapid Communication, medicine.medical_specialty, 2019-20 coronavirus outbreak, Surveillance data, Coronavirus disease 2019 (COVID-19), COVID-19 pandemic, Respiratory Syncytial Virus Infections, Biology, Virus, 03 medical and health sciences, MESH: Respiratory Syncytial Virus Infections, Virology, medicine, Humans, MESH: SARS-CoV-2, MESH: Humans, SARS-CoV-2, Public Health, Environmental and Occupational Health, Small children, COVID-19, Infant, MESH: France, 030104 developmental biology, Respiratory Syncytial Virus, Human, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, MESH: Europe, MESH: Seasons
Abstract

International audience; Since the introduction of non-pharmacological interventions to control COVID-19, respiratory syncytial virus (RSV) activity in Europe has been limited. Surveillance data for 17 countries showed delayed RSV epidemics in France (≥ 12 w) and Iceland (≥ 4 w) during the 2020/21 season. RSV cases (predominantly small children) in France and Iceland were older compared with previous seasons. We hypothesise that future RSV epidemic(s) could start outside the usual autumn/winter season and be larger than expected. Year-round surveillance of RSV is of critical importance.

Published
2021

45. Characteristics of the delayed respiratory syncytial virus epidemic, 2020/2021, Rhône Loire, France

Author

Casalegno, Jean-Sebastien, Ploin, Dominique, Cantais, Aymeric, Masson, Elsa, Bard, Emilie, Valette, Martine, Fanget, Remi, Targe, Sandrine Couray, Myar-Dury, Anne-Florence, Doret-Dion, Muriel, Massoud, Mona, Queromes, Gregory, Vanhems, Philippe, Claris, Olivier, Butin, Marine, Pillet, Sylvie, Ader, Florence, Bin, Sylvie, Gaymard, Alexandre, Lina, Bruno, Morfin, Florence, Javouhey, Etienne, Gillet, Yves, Ouziel, Antoine, Tardy, Jean-claude, Gaucherand, Pascal, Panetta, Luc, Massardier, Jerome, Polazzi, Stephanie, Duclos, Antoine, Benchaib, Mehdi, Cartier, Regine, Jourdain, Marine, Ottmann, Michelle, Kramer, Rolf, Fiorini, Sylvie, Rivat, Nathalie, Mekki, Yahia, Fort-Jacquier, Julie, Barral, Maud-Catherine, Noelie, Vey, Haesebaert, Julie, Horvat, Come, Vidoni, Leo, Reynes, Jean-Marc, Eleouet, Jean-Francois, Josset, Laurence, Receveur, Matthieu, Institut des Agents Infectieux [Lyon] (IAI), Hospices Civils de Lyon (HCL), Centre National de Référence des Virus des Infections Respiratoires (dont la Grippe) [Lyon] (CNR - laboratoire associé), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Virology and human respiratory Pathologies - Virology and human respiratory Pathologies (VirPath), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hôpital Femme Mère Enfant [CHU - HCL] (HFME), Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] (CHU ST-E), Groupe Immunité des Muqueuses et Agents Pathogènes (GIMAP), Université Jean Monnet - Saint-Étienne (UJM), Hôpital Edouard Herriot [CHU - HCL], Santé publique, épidémiologie et écologie évolutive des maladies infectieuses (PHE3ID), Pôle Information Médicale Evaluation Recherche (IMER), Hôpital de la Croix-Rousse [CHU - HCL], VRS study group in Lyon: Antoine Ouziel, Jean-claude Tardy, Pascal Gaucherand, Luc Panetta, Jerome Massardier, Stephanie Polazzi, Antoine Duclos, Mehdi Benchaib, Regine Cartier, Marine Jourdain, Michelle Ottmann, Rolf Kramer, Sylvie Fiorini, Nathalie Rivat, Yahia Mekki, Julie Fort-Jacquier, Maud-Catherine Barral, Vey Noelie, Julie Haesebaert, Come Horvat, Leo Vidoni, Jean-Marc Reynes, Jean-Francois Eleouet, Laurence Josset, Matthieu Receveur, Reynes, Jean-Marc, Centre National de Référence des Virus des Infections Respiratoires (dont la Grippe) [Lyon] (CNR), Centre International de Recherche en Infectiologie - UMR (CIRI), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), and Centre Hospitalier Universitaire de Saint-Etienne (CHU de Saint-Etienne)

Subjects
0301 basic medicine, Pediatrics, Epidemiology, pharmacological interventions, MESH: Hospitalization, MESH: Respiratory Syncytial Virus, Human, disease burden, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Child, 030212 general & internal medicine, Respiratory system, Child, Respiratory Tract Infections, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Respiratory tract infections, Incidence (epidemiology), RSV, MESH: Infant, Hospitalization, non-pharmacological interventions, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, bronchiolitis, France, Rapid Communication, Adult, medicine.medical_specialty, Respiratory Syncytial Virus Infections, Virus, MESH: Respiratory Syncytial Virus Infections, 03 medical and health sciences, Virology, Lower respiratory tract infection, medicine, Humans, Epidemics, MESH: Epidemics, Disease burden, MESH: Humans, business.industry, SARS-CoV-2, Public Health, Environmental and Occupational Health, Outbreak, COVID-19, Infant, MESH: Adult, medicine.disease, MESH: France, 030104 developmental biology, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Bronchiolitis, Respiratory Syncytial Virus, Human, MESH: Respiratory Tract Infections, SARI, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business
Abstract

International audience; The Rhône-Loire metropolitan areas’ 2020/21 respiratory syncytial virus (RSV) epidemic was delayed following the implementation of non-pharmaceutical interventions (NPI), compared with previous seasons. Very severe lower respiratory tract infection incidence among infants ≤ 3 months decreased twofold, the proportion of cases among children aged > 3 months to 5 years increased, and cases among adults > 65 years were markedly reduced. NPI appeared to reduce the RSV burden among at-risk groups, and should be promoted to minimise impact of future RSV outbreaks.

Published
2021

46. Fetal growth restriction: underdiagnosed condition with non-optimal screening

Author

Atallah, Anthony, Butin, Marine, Moret, Stéphanie, Claris, Olivier, Gaucherand, Pascal, and Doret-Dion, Muriel

Abstract

Fetal Growth restriction (FGR) is the pathological failure of a fetus to reach its biologically determined growth potential. Detection of FGR fetuses is a universally agreed key objective of antenatal care. Antenatal detection of FGR has undeniable benefits, juggling between intensive fetal surveillance and optimized timing of delivery; it reduces adverse perinatal outcomes by up to four-fold. However, FGR is still widely underdiagnosed. We aimed to identify the prevalence of FGR diagnosis in our wards and study the impact of the 2013 published French guidelines on the detection rate of FGR. The secondary objective aimed to highlight the factors of suboptimal screening in the population of non-diagnosed FGR fetuses and emphasize the screening method that led to antenatal diagnosis of FGR. We conducted a retrospective study at a single tertiary maternity center in Lyon-France, the Femme Mère Enfant Hospital, including the exhaustive population of FGR born after 24 + 0 weeks of gestation from 1 January 2011 to 31 December 2017. FGR was defined combining the neonatal and antenatal consensus-based definitions for early and late FGR in absence of congenital anomalies, excluding small for gestational age fetuses. For all FGR fetuses, we compared the antenatal detection rate of FGR during 2011–2013 to 2015–2017, since the French guidelines were published in December 2013. When FGR fetuses underwent an antenatal diagnosis of FGR, we retrospectively collected the characteristics that led to the diagnosis. When fetuses were not diagnosed as FGR, we retrospectively reviewed the implementation of the recommended screening method, enabling to evaluate whether screening was optimal or not. Statistical analysis was performed in July 2018, and statistical significance was regarded as a p-value p = .59). In the population of non-diagnosed FGR infants, screening was suboptimal in 80%. Symphysis-fundal height (SFH) was not measured in 10.7%, with no difference before and after 2014 (7.3 versus 11.8% p = .11). Ultrasound examination for fetal biometry had not been prescribed in spite of abnormal SFH in 47.7% of undiagnosed FGR infants. Diagnosis has been missed in 11.5% of infants because of misinterpretation of the estimated fetal weight’s centile. FGR is widely underdiagnosed. However, the limited performances can partially be explained by the regular misuse of screening method in clinical practice. Despite the systematic third trimester ultrasound screening, the detection rate of FGR was similar to the one reported in the medical literature. The timing of routine third trimester ultrasound in low-risk women may be rethought.

Published
2021
Full Text
View/download PDF

47. Identifying the Target Population for Primary Respiratory Syncytial Virus Two-Step Prevention in Infants: Normative Outcome of Hospitalisation Assessment for Newborns (NOHAN).

Author

Jourdain, Marine, Benchaib, Mehdi, Ploin, Dominique, Gillet, Yves, Javouhey, Etienne, Horvat, Come, Massoud, Mona, Butin, Marine, Claris, Olivier, Lina, Bruno, and Casalegno, Jean-Sebastien

Subjects
RESPIRATORY syncytial virus, NEWBORN screening, INFANTS, MOTHER-infant relationship, BIRTH weight, HUMAN metapneumovirus infection
Abstract

Background: Respiratory syncytial virus (RSV) is the leading cause of acute respiratory infection- related hospitalisations in infants (RSVh). Most of these infants are younger than 6 months old with no known risk factors. An efficient RSVh prevention program should address both mothers and infants, relying on Non-Pharmaceutical (NPI) and Pharmaceutical Interventions (PI). This study aimed at identifying the target population for these two interventions. Methods: Laboratory-confirmed RSV-infected infants hospitalised during the first 6 months of life were enrolled from the Hospices Civils de Lyon birth cohort (2014 to 2018). Clinical variables related to pregnancy and birth (sex, month of birth, birth weight, gestational age, parity) were used for descriptive epidemiology, multivariate logistic regression, and predictive score development. Results: Overall, 616 cases of RSVh in 45,648 infants were identified. Being born before the epidemic season, prematurity, and multiparity were independent predictors of RSVh. Infants born in January or June to August with prematurity and multiparity, and those born in September or December with only one other risk factor (prematurity or multiparity) were identified as moderate-risk, identifying the mothers as candidates for a first-level NPI prevention program. Infants born in September or December with prematurity and multiparity, and those born in October or November were identified as high-risk, identifying the mothers and infants as candidates for a second-level (NPI and PI) intervention. Conclusions: It is possible to determine predictors of RSVh at birth, allowing early enrollment of the target population in a two-level RSV prevention intervention. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

48. Early Adjuvant Medication With the mTOR Inhibitor Sirolimus in a Preterm Neonate With Compressive Cystic Lymphatic Malformation

Author

Honnorat, Marion, Viremouneix, Loïc, Ayari, Sonia, Guibaud, Laurent, Coste, Karen, Claris, Olivier, and Butin, Marine

Subjects
sirolimus, mTOR inhibitor, sclerotherapy, Case Report, preterm, Pediatrics, lymphangioma
Abstract

Cystic lymphatic malformations result from an abnormal embryological development of the lymphatic structures. Here we report on a case of a preterm female baby, born at 34 weeks of gestation, with a voluminous cervicofacial cystic lymphatic malformation responsible for an airway obstruction. An mTOR inhibitor, sirolimus, was started from the first day of life, and was combined with iterative sclerotherapy procedures. This case illustrates a safe and successful early administration of sirolimus in a preterm neonate.

Published
2020

49. BURDEN OF HOSPITALIZATION DUE TO RESPIRATORY SYNCYTIAL VIRUS (RSV)-VERY SEVERE ASSOCIATED LOWER RESPIRATORY TRACT INFECTION (VS-ALRI) IN THE FIRST YEAR OF LIFE IN A MAJOR URBAN CITY, LYON, FRANCE. On behalf the VRS Study group in Lyon

Author

C Horvat, L Duclaux-Loras, A Myard-Dury, B Lina, E Javouhey, Y Gillet, J S Casalegno, Ottmann, Michele, Ploin, Dominique, Gaymard, Alexandre, Kramer, Rolf, Benchaib, Mehdi, Yahia Mekki, Javouhey, Etienne, Duclos, Antoine, Gillet, Yves, Polazzi, Stephanie, Lina, Bruno, Vanhems, Philippe, Claris, Olivier, Valette, Martine, Couray-Targe, Sandrine, Massoud, Mona, Cartier, Régine, Josset, Laurence, Butin, Marine, Bin, Sylvie, Horvat, Côme, Jean-Sebastien Casalegno, Jourdain, Marine, Ouziel, Antoine, Anne-Florence Myard-Dury, Doret-Dion, Muriel, Fiorini, Sylvie, Morfin-Sherpa, Florence, Gaucherand, Pascal, Ader, Florence, Rivat, Nathalie, and Lyon, The VRS Study Group In

Published
2020
Full Text
View/download PDF

50. Very severe RSV-associated respiratory tract infection in children living in a French urban city: Incidence and risk factors (ESPID 2020)

Author

L Duclos-Lauras, L Alexandre, A Paul, T Guichard, E Rault, S Fiorini, N Rivat, Ploin, Dominique, Benchaib, Mehdi, Kramer, Rolf, Yahia Mekki, Duclos, Antoine, Javouhey, Etienne, Gillet, Yves, Lina, Bruno, Vanhems, Philippe, Claris, Olivier, Valette, Martine, Couray-Targe, Sandrine, Massoud, Mona, Cartier, Régine, Lyon, The VRS Study Group In, Morfin-Sherpa, Florence, Ottmann, Michele, Bin, Sylvie, Butin, Marine, Horvat, Côme, Jourdain, Marine, Biot, Blandine, Ouziel, Antoine, Doret-Dion, Muriel, Gaucherand, Pascal, Massardier, Jerome, Anne-Florence Myard-Dury, Polazzi, Stephanie, and Jean-Sebastien Casalegno

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results