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3. Modulation of acetylcholine in the neostriatum by dopamine and 5-hydroxytryptamine.

Author

Butcher SH and Cho AK

Subjects
Animals, Caudate Nucleus drug effects, Choline metabolism, Female, Male, Pimozide pharmacology, Putamen drug effects, Rats, Time Factors, p-Chloroamphetamine pharmacology, Acetylcholine metabolism, Caudate Nucleus metabolism, Corpus Striatum metabolism, Dopamine pharmacology, Putamen metabolism, Serotonin pharmacology
Published
1976

5. Fast fixation of brain in situ by high intensity microwave irradiation: application to neurochemical studies.

Author

Butcher SH, Butcher LL, Harms MS, and Jendent DJ

Subjects
Acetylcholine analysis, Acetylcholinesterase analysis, Animals, Choline analysis, Dihydrolipoamide Dehydrogenase analysis, Male, Rats, Brain Chemistry, Heating, Histocytochemistry methods, Microwaves
Abstract

The levels of acetylcholine and choline were measured in various brain regions of the rat after fixation by microwave irradiation of the head and after decapitation and subsequent freezing in liquid nitrogen. Levels of acetylcholine were increased by approximately 50% after microwave irradiation, while choline levels were reduced. These biochemical findings were correlated with virtually complex loss of acetylcholinesterase and NADH-diaphorase activity after 1 s exposure to microwave irradiation at a level of 5 kW.

Published
1976
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