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Each additional decade of type 2 diabetes shortens lives by about 3.5 years, compared with not having diabetes, researchers estimate on the basis of data from studies conducted in 19 [...]

COMPARED WITH INFANTS who were not exposed to COVID-19 in the womb, those who were exposed had a lower weight and body mass index (BMI) at birth, but greater weight [...]

IN A NATIONAL STUDY of older Danes who had previously had a fracture and were taking bisphosphonates, the risk of having a serious though rare atypical femoral fracture (AFF) was [...]

In the largest randomized controlled trial of an automated insulin delivery (AID) system (hybrid closed-loop) versus standard insulin delivery in pregnant women with type 1 diabetes, the automated CamAPS FX [...]

Attendees at ObesityWeek[R] 2022 listened with much excitement to the results of the STEP TEENS phase 3 trial of once-weekly subcutaneous semaglutide 2.4 mg (Wegovy) in adolescents aged 12 up [...]

SAN DIEGO -- Weight loss with tirzepatide was fairly uniform across different body mass index ranges, ages, and number of obesity-related comorbidities in patients with overweight/obesity without type 2 diabetes. [...]

Although multiple international medical societies over recent years have recommended lowering the threshold for bariatric surgery to a body mass index (BMI, in kg/[m.sup.2]) of 30-35 (class 1 obesity) in [...]

Middle-aged White women who had higher levels of some breakdown products of phthalates - a class of endocrine disrupting chemicals (EDCs), or 'forever chemicals,' that act as plasticizers - had [...]

Adults with mainly type 2 diabetes had gaps in the use of medications for managing blood glucose, hypertension, and lipids, in an analysis of nationally representative U.S. survey data. A [...]

THE AMERICAN COLLEGE of Sports Medicine has issued new recommendations for exercise/physical activity in people with type 2 diabetes, which update a 2010 joint ACSM/American Diabetes Association position statement. The [...]

Researchers found a small but greater risk of a hip fracture after 2 years of taking a 'drug holiday'--stopping therapy--after long-term ([greater than or equal to]3-year) use of one bisphosphonate, [...]

In a meta-analysis of more than 1 million mothers, those who breastfed their children had an 11%-17% lower risk of developing cardiovascular disease, coronary heart disease (CHD), or stroke, and [...]

Researchers found a small but greater risk of a hip fracture after 2 years of taking a 'drug holiday'--stopping therapy--after long-term ([greater than or equal to]3-year) use of one bisphosphonate, [...]

The STEP 5 clinical trial extends favorable weight loss from 1 year out to 2 years for the glucagon-like peptide-1 (GLP-1) agonist semaglutide (Wegovy, Novo Nordisk), given as a once-weekly [...]

Higher intake of vegetable fats from foods such as olive oil and nuts is associated with a lower risk for stroke, whereas people who eat more animal fats, especially processed [...]

The STEP 5 clinical trial extends favorable weight loss from 1 year out to 2 years for the glucagon-like peptide-1 (GLP-1) agonist semaglutide (Wegovy, Novo Nordisk), given as a once-weekly [...]

An 8-month high-intensity resistance and impact training program (HiRIT, Onero) led to greater gains in lumbar spine bone mineral density (BMD) and leg/back strength than a low-intensity Pilates-based program (Buff [...]

AN 8-MONTH high-intensity resistance and impact training program (HiRIT, Onero) led to greater gains in lumbar spine bone mineral density (BMD) and leg/back strength than a low-intensity Pilates-based program (Buff [...]

The Crystal Bone (Amgen) novel algorithm predicted 2-year risk of osteoporotic fractures in a large dataset with an accuracy that was consistent with FRAX 10-year risk predictions, researchers report. The [...]

PATIENTS WITH IRON overload - serum ferritin greater than 1,000 mcg/L or a diagnosis of hemochromatosis or thalassemia - were 60% more likely to have an osteoporotic fracture during an [...]

Patients with type 2 diabetes who received empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, were almost 40% less likely to have a kidney stone than patients who received placebo during [...]

An intensive 1-year behavior therapy program aimed at changing a person's response to food 'cues' might help people with obesity lose a modest amount of weight, a randomized clinical trial [...]

THE HEALTH BENEFITS of intermittent fasting are slowly being clarified as more evidence continues to emerge, say the authors of a new review of 21 studies. Initial findings suggest that [...]

Researchers found a small but greater risk of a hip fracture after 2 years of taking a 'drug holiday'--stopping therapy -after long-term (>3-year) use of one bisphosphonate, risedronate, versus another, [...]

Clinicians need to pay more attention to high levels of lipoprotein cholesterol (LDL-C)--a marker of cardiovascular disease (CVD) risk--in patients with type 2 diabetes, a new population-based study in Finland [...]

The glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide (Saxenda, Novo Nordisk) was safe and effective for treating weight regain after Roux-en-Y gastric bypass (RYGB), in a randomized controlled trial. That is, [...]

Higher intake of vegetable fats from foods such as olive oil and nuts is associated with a lower risk for stroke, whereas people who eat more animal fats, especially processed [...]

Among postmenopausal women who received an epidural steroid injection (ESI) in the lumbar spine to treat back and leg pain arising from a compressed nerve in the spine, levels of [...]

FROM ASBMR A large international team of experts has developed two comprehensive guidelines for diagnosing, evaluating, and managing hypoparathyroidism and hyperparathyroidism, which replace guidelines issued 5 and 7 years ago. [...]

An 8-month high-intensity resistance and impact training program (HiRIT, Onero) led to greater gains in lumbar spine bone mineral density (BMD) and leg/back strength than a low-intensity Pilates-based program (Buff [...]

A first-in-class, macrophage-regulating, wound-healing cream for diabetic foot ulcers has shown benefit over absorbent dressings in a phase 3 trial, with another trial ongoing. The product, ON101 (Fespixon) became available [...]

A 'quadpill' containing quarter doses of four blood pressure (BP)-lowering medications was more effective than monotherapy for initial treatment of hypertension, with similar tolerability, in the 1-year, phase 3 QUARTET [...]

Whereas previous scientific statements from the American Heart Association have addressed how diet, physical activity, and weight control can help prevent and manage hypertension, a new AHA statement focuses on [...]

A 'quadpill' containing quarter doses of four blood pressurelowering medications was more effective than monotherapy for initial treatment of hypertension, with similar tolerability in the 1 -year, phase 3 QUARTET [...]

Among adults at high risk of type 2 diabetes - the leading cause of kidney disease - those who received vitamin D supplements as opposed to placebo for close to [...]