431 results on '"Busby, John"'
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2. Clinical and Economic Burden of Severe Asthma With Low Blood Eosinophil Counts
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Busby, John, Menon, Shruti, Martin, Neil, Lipworth, Joe, Zhang, Ruiqi, Burhan, Hassan, Brown, Thomas, Chaudhuri, Rekha, Gore, Robin, Jackson, David J., Naveed, Shamsa, Pantin, Thomas, Pfeffer, Paul E., Patel, Mitesh, Patel, Pujan H., Rupani, Hitasha, and Heaney, Liam G.
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- 2024
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3. Cognitive and psychiatric symptom trajectories 2–3 years after hospital admission for COVID-19: a longitudinal, prospective cohort study in the UK
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Lone, Nazir, Baillie, Kenneth, Pairo-Castineira, Erola, Avramidis, Nikos, Wain, Louise, Guillen-Guio, Beatriz, Leavy, Olivia, Jones, S, Armstrong, Lisa, Hairsine, Brigid, Henson, Helen, Kurasz, Claire, Shaw, Alison, Shenton, Liz, Dobson, Hannah, Dell, Amanda, Fairbairn, Sara, Hawkings, Nancy, Haworth, Jill, Hoare, Michaela, Lewis, Victoria, Lucey, Alice, Mallison, Georgia, Nassa, Heeah, Pennington, Chris, Price, Andrea, Price, Claire, Storrie, Andrew, Willis, Gemma, Young, Susan, Poinasamy, Krisnah, Walker, Samantha, Jarrold, Ian, Rawlik, Konrad, Sanderson, Amy, Chong-James, K, David, C, James, W Y, Pfeffer, Paul, Zongo, O, Martineau, Adrian, Manisty, C, Armour, Cherie, Brown, Vanessa, Busby, John, Connolly, Bronwen, Craig, Thelma, Drain, Stephen, Heaney, Liam, King, Bernie, Magee, Nick, Major, E, McAulay, Danny, McGarvey, Lorcan, McGinness, Jade, Peto, Tunde, Stone, Roisin, Bolger, Annette, Davies, Ffyon, Haggar, Ahmed, Lewis, Joanne, Lloyd, Arwel, Manley, R, McIvor, Emma, Menzies, 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Ian, Hufton, E, Johnson, Simon, Khan, Fasih, Kitterick, Paaig, Morriss, Richard, Selby, Nick, Wright, Louise, Antoniades, Charalambos, Bates, A, Beggs, M, Bhui, Kamaldeep, Breeze, Katie, Channon, K M, Clark, David, Fu, X, Husain, Masud, Li, X, Lukaschuk, E, McCracken, Celeste, McGlynn, K, Menke, R, Motohashi, K, Nichols, T E, Ogbole, Godwin, Piechnik, S, Propescu, I, Propescu, J, Samat, A A, Sanders, Z B, Sigfrid, Louise, Webster, M, Kingham, Lucy, Klenerman, Paul, Lamlum, Hanan, Taquet, Maxime, Carson, G, Finnigan, L, Saunders, Laura, Wild, James, Calder, P C, Huneke, Nathan, Simons, Gemma, Baldwin, David, Bain, Steve, Daines, Luke, Bright, E, Crisp, P, Dharmagunawardena, Ruvini, Stern, M, Bailey, Elisabeth, Reddington, Anne, Wight, Andrew, Ashish, A, Cooper, Josh, Robinson, Emma, Broadley, Andrew, Barman, Laura, Brookes, Claire, Elliott, K, Griffiths, L, Guy, Zoe, Howard, Kate, Ionita, Diana, Redfearn, Heidi, Sarginson, Carol, Turnbull, Alison, Skorniewska, Zuzanna, De Deyn, Thomas, Hampshire, Adam, Trender, William R, Hellyer, Peter J, Chalmers, James D, Ho, Ling-Pei, Leavy, Olivia C, Richardson, Matthew, McAuley, Hamish J C, Singapuri, Amisha, Saunders, Ruth M, Harris, Victoria C, Greening, Neil J, Mansoori, Parisa, Harrison, Ewen M, Docherty, Annemarie B, Lone, Nazir I, Quint, Jennifer, Brightling, Christopher E, Wain, Louise V, Evans, Rachael A, Geddes, John R, and Harrison, Paul J
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- 2024
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4. Exploring Definitions and Predictors of Response to Biologics for Severe Asthma
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Scelo, Ghislaine, Tran, Trung N., Le, Tham T., Fagerås, Malin, Dorscheid, Delbert, Busby, John, Al-Ahmad, Mona, Al-Lehebi, Riyad, Altraja, Alan, Beastall, Aaron, Bergeron, Celine, Bjermer, Leif, Bjerrum, Anne S., Cano-Rosales, Diana Jimena, Canonica, Giorgio Walter, Carter, Victoria, Charriot, Jeremy, Christoff, George C., Cosio, Borja G., Denton, Eve, Fernandez-Sanchez, Maria Jose, Fonseca, João A., Gibson, Peter G., Goh, Celine, Heaney, Liam G., Heffler, Enrico, Hew, Mark, Iwanaga, Takashi, Katial, Rohit, Koh, Mariko S., Kuna, Piotr, Larenas-Linnemann, Désirée, Lehtimäki, Lauri, Mahboub, Bassam, Martin, Neil, Matsumoto, Hisako, Menzies-Gow, Andrew N., Papadopoulos, Nikolaos G., Patel, Pujan, Perez-De-Llano, Luis, Peters, Matthew, Pfeffer, Paul E., Popov, Todor A., Porsbjerg, Celeste M., Rhee, Chin K., Sadatsafavi, Mohsen, Taillé, Camille, Torres-Duque, Carlos A., Tsai, Ming-Ju, Ulrik, Charlotte S., Upham, John W., von Bülow, Anna, Wang, Eileen, Wechsler, Michael E., and Price, David B.
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- 2024
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5. Impact of comorbidities on EQ-5D quality-of-life index in severe asthma
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Doherty, Martin, Masoli, Matthew, Pfeffer, Paul E., Brown, Thomas, Chaudhuri, Rekha, Faruqi, Shoaib, Gore, Robin, Heaney, Liam G., Mansur, Adel H., Pantin, Thomas, Patel, Mitesh, Rupani, Hitasha, Siddiqui, Salman, Vyas, Aashish, and Busby, John
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- 2024
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6. International Variation in Severe Exacerbation Rates in Patients With Severe Asthma
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Lee, Tae Yoon, Price, David, Yadav, Chandra Prakash, Roy, Rupsa, Lim, Laura Huey Mien, Wang, Eileen, Wechsler, Michael E., Jackson, David J., Busby, John, Heaney, Liam G., Pfeffer, Paul E., Mahboub, Bassam, Perng (Steve), Diahn-Warng, Cosio, Borja G., Perez-de-Llano, Luis, Al-Lehebi, Riyad, Larenas-Linnemann, Désirée, Al-Ahmad, Mona, Rhee, Chin Kook, Iwanaga, Takashi, Heffler, Enrico, Canonica, Giorgio Walter, Costello, Richard, Papadopoulos, Nikolaos G., Papaioannou, Andriana I., Porsbjerg, Celeste M., Torres-Duque, Carlos A., Christoff, George C., Popov, Todor A., Hew, Mark, Peters, Matthew, Gibson, Peter G., Maspero, Jorge, Bergeron, Celine, Cerda, Saraid, Contreras-Contreras, Elvia Angelica, Chen, Wenjia, and Sadatsafavi, Mohsen
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- 2024
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7. Oral prednisolone and warfarin and risk of oesophageal cancer: A case-control study.
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Cardwell, Chris R., McDowell, Ronald D., Hughes, Carmel M., Busby, John, and Murchie, Peter
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- 2024
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8. Impact of pre-biologic impairment on meeting domain-specific biologic responder definitions in patients with severe asthma
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Perez-de-Llano, Luis, Scelo, Ghislaine, Canonica, G. Walter, Chen, Wenjia, Henley, William, Larenas-Linnemann, Désirée, Peters, Matthew J., Pfeffer, Paul E., Tran, Trung N., Ulrik, Charlotte Suppli, Popov, Todor A., Sadatsafavi, Mohsen, Hew, Mark, Máspero, Jorge, Gibson, Peter G., Christoff, George C., Fitzgerald, J. Mark, Torres-Duque, Carlos A., Porsbjerg, Celeste M., Papadopoulos, Nikolaos G., Papaioannou, Andriana I., Heffler, Enrico, Iwanaga, Takashi, Al-Ahmad, Mona, Kuna, Piotr, Fonseca, João A., Al-Lehebi, Riyad, Rhee, Chin Kook, Koh, Mariko Siyue, Cosio, Borja G., Perng (Steve), Diahn-Warng, Mahboub, Bassam, Menzies-Gow, Andrew N., Jackson, David J., Busby, John, Heaney, Liam G., Patel, Pujan H., Wang, Eileen, Wechsler, Michael E., Altraja, Alan, Lehtimäki, Lauri, Bourdin, Arnaud, Bjermer, Leif, Bulathsinhala, Lakmini, Carter, Victoria, Murray, Ruth, Beastall, Aaron, Denton, Eve, and Price, David B.
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- 2024
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9. Pharmacoequity in Allergy-Immunology: Disparities in Access to Medications for Allergic Diseases and Proposed Solutions in the United States and Globally
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Maldonado-Puebla, Martin, Akenroye, Ayobami, Busby, John, Cardet, Juan Carlos, and Louisias, Margee
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- 2024
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10. Longitudinal Assessment of Glucocorticoid Toxicity Reduction in Patients With Severe Asthma Treated With Biologic Therapies
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McDowell, P. Jane, Busby, John, Stone, John H., Butler, Claire A., and Heaney, Liam G.
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- 2024
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11. Analysis of comorbidities and multimorbidity in adult patients in the International Severe Asthma Registry
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Scelo, Ghislaine, Torres-Duque, Carlos A., Maspero, Jorge, Tran, Trung N., Murray, Ruth, Martin, Neil, Menzies-Gow, Andrew N., Hew, Mark, Peters, Matthew J., Gibson, Peter G., Christoff, George C., Popov, Todor A., Côté, Andréanne, Bergeron, Celine, Dorscheid, Delbert, FitzGerald, J. Mark, Chapman, Kenneth R., Boulet, Louis Philippe, Bhutani, Mohit, Sadatsafavi, Mohsen, Jiménez-Maldonado, Libardo, Duran-Silva, Mauricio, Rodriguez, Bellanid, Celis-Preciado, Carlos Andres, Cano-Rosales, Diana Jimena, Solarte, Ivan, Fernandez-Sanchez, Maria Jose, Parada-Tovar, Patricia, von Bülow, Anna, Bjerrum, Anne Sofie, Ulrik, Charlotte S., Assing, Karin Dahl, Rasmussen, Linda Makowska, Hansen, Susanne, Altraja, Alan, Bourdin, Arnaud, Taille, Camille, Charriot, Jeremy, Roche, Nicolas, Papaioannou, Andriana I., Kostikas, Konstantinos, Papadopoulos, Nikolaos G., Salvi, Sundeep, Long, Deirdre, Mitchell, Patrick D., Costello, Richard, Sirena, Concetta, Cardini, Cristina, Heffler, Enrico, Puggioni, Francesca, Canonica, Giorgio Walter, Guida, Giuseppe, Iwanaga, Takashi, Al-Ahmad, Mona, Linnemann, Désirée Larenas, Garcia, Ulises, Kuna, Piotr, Fonseca, João A., Al-Lehebi, Riyad, Koh, Mariko Siyue, Rhee, Chin Kook, Cosio, Borja G., de Llano, Luis Perez, Perng (Steve), Diahn-Warng, Huang, Erick Wan-Chun, Wang, Hao-Chien, Tsai, Ming-Ju, Mahboub, Bassam, Salameh, Laila Ibraheem Jaber, Jackson, David, Busby, John, Heaney, Liam G., Pfeffer, Paul, Goddard, Amanda Grippen, Wang, Eileen, Hoyte, Flavia, Wechsler, Michael E., Chapman, Nicholas, Katial, Rohit, Carter, Victoria, Bulathsinhala, Lakmini, Eleangovan, Neva, Ariti, Con, Lyu, Juntao, Price, David B., and Porsbjerg, Celeste
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- 2024
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12. Blood transcriptomic signature in type-2 biomarker-low severe asthma and asthma control
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Zeng, Xue, Qing, Jing, Li, Chi-Ming, Lu, Jiamiao, Yamawaki, Tracy, Hsu, Yi-Hsiang, Vander Lugt, Bryan, Hsu, Hailing, Busby, John, McDowell, P.J., Jackson, David J., Djukanovic, Ratko, Matthews, John G., Arron, Joseph R., Bradding, Peter, Brightling, Christopher E., Chaudhuri, Rekha, Choy, David F., Cowan, D., Fowler, S.J., Hardman, Timothy C., Harrison, Tim, Howarth, Peter, Lordan, James, Mansur, A.H., Menzies-Gow, Andrew, Pavord, Ian D., Walker, Samantha, Woodcock, Ashley, and Heaney, Liam G.
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- 2023
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13. Impact of Initiating Biologics in Patients With Severe Asthma on Long-Term Oral Corticosteroids or Frequent Rescue Steroids (GLITTER): Data From the International Severe Asthma Registry
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Chen, Wenjia, Tran, Trung N., Sadatsafavi, Mohsen, Murray, Ruth, Wong, Nigel Chong Boon, Ali, Nasloon, Ariti, Con, Bulathsinhala, Lakmini, Gil, Esther Garcia, FitzGerald, J. Mark, Alacqua, Marianna, Al-Ahmad, Mona, Altraja, Alan, Al-Lehebi, Riyad, Bhutani, Mohit, Bjermer, Leif, Bjerrum, Anne-Sofie, Bourdin, Arnaud, von Bülow, Anna, Busby, John, Canonica, Giorgio Walter, Carter, Victoria, Christoff, George C., Cosio, Borja G., Costello, Richard W., Fonseca, João A., Gibson, Peter G., Yoo, Kwang-Ha, Heaney, Liam G., Heffler, Enrico, Hew, Mark, Hilberg, Ole, Hoyte, Flavia, Iwanaga, Takashi, Jackson, David J., Jones, Rupert C., Koh, Mariko Siyue, Kuna, Piotr, Larenas-Linnemann, Désirée, Lehmann, Sverre, Lehtimäki, Lauri, Lyu, Juntao, Mahboub, Bassam, Maspero, Jorge, Menzies-Gow, Andrew N., Newell, Anthony, Sirena, Concetta, Papadopoulos, Nikolaos G., Papaioannou, Andriana I., Perez-de-Llano, Luis, Perng (Steve), Diahn-Warng, Peters, Matthew, Pfeffer, Paul E., Porsbjerg, Celeste M., Popov, Todor A., Rhee, Chin Kook, Salvi, Sundeep, Taillé, Camille, Taube, Christian, Torres-Duque, Carlos A., Ulrik, Charlotte, Ra, Seung-Won, Wang, Eileen, Wechsler, Michael E., and Price, David B.
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- 2023
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14. UK Biobank: a globally important resource for cancer research
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Conroy, Megan C., Lacey, Ben, Bešević, Jelena, Omiyale, Wemimo, Feng, Qi, Effingham, Mark, Sellers, Jonathan, Sheard, Simon, Pancholi, Mahesh, Gregory, Gareth, Busby, John, Collins, Rory, and Allen, Naomi E.
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- 2023
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15. Orchid diversity and occurrence in relation to past fire in Canberra Nature Park
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Mulvaney, Michael, Seddon, Julian, Wood, Tony, Busby, Cath, Hayashi, Tobias, Busby, John, Andrews, Jenny, Baines, Greg, Baird, Ian, Billings, Dale, Clarke, Margaret, Cook, Emma, Coyne, Peter, Dears, Nigel, Falconer, Ian, Free, Sybil, Gilbert, Catherine, Jeffrey, Jeanette, Johnson, Luke, Kitchin, Margaret, Lebedinsky, Eyal, Lynch, Joanne, MacDonald, Colin, MacKenzie, Jason, Maher, Sheridan, Malbon, Jennifer, McInnes, Alison, McGuire, Anna, Mikhailovich, Nic, Mullaney, Matthew, Parker, Ryl, Pope, David, Potapowicz, Maya, Quinn, Peter, Purdie, Rosemary, Ramshaw, Peter, Robertson, John, Robinson, Edwina, Russell, Janet, Smits, Jenni, Taws, Nicki, Velasquez, Diwani, Widdowson, Jennie, Wilson, Graham, Wilson, Nick, Worner, Debbie, and BHL Australia
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- 2020
16. A Randomized Trial of a Composite T2-Biomarker Strategy Adjusting Corticosteroid Treatment in Severe Asthma: A Post Hoc Analysis by Sex
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Eastwood, Matthew C., Busby, John, Jackson, David J., Pavord, Ian D., Hanratty, Catherine E., Djukanovic, Ratko, Woodcock, Ashley, Walker, Samantha, Hardman, Timothy C., Arron, Joseph R., Choy, David F., Bradding, Peter, Brightling, Chris E., Chaudhuri, Rekha, Cowan, Douglas, Mansur, Adel H., Fowler, Stephen J., Howarth, Peter, Lordan, James, Menzies-Gow, Andrew, Harrison, Timothy, Robinson, Douglas S., Holweg, Cecile T.J., Matthews, John G., and Heaney, Liam G.
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- 2023
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17. Corticosteroid Responsiveness Following Mepolizumab in Severe Eosinophilic Asthma—A Randomized, Placebo-Controlled Crossover Trial (MAPLE)
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Yang, Freda, Busby, John, Heaney, Liam G., Pavord, Ian D., Brightling, Chris E., Borg, Katie, McDowell, Jane P., Diver, Sarah E., Shrimanker, Rahul, Bradding, Peter, Shepherd, Malcolm, and Chaudhuri, Rekha
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- 2022
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18. Global Variability in Administrative Approval Prescription Criteria for Biologic Therapy in Severe Asthma
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Porsbjerg, Celeste M., Menzies-Gow, Andrew N., Tran, Trung N., Murray, Ruth B., Unni, Bindhu, Audrey Ang, Shi Ling, Alacqua, Marianna, Al-Ahmad, Mona, Al-Lehebi, Riyad, Altraja, Alan, Belevskiy, Andrey S., Björnsdóttir, Unnur S., Bourdin, Arnaud, Busby, John, Canonica, G. Walter, Christoff, George C., Cosio, Borja G., Costello, Richard W., FitzGerald, J. Mark, Fonseca, João A., Hansen, Susanne, Heaney, Liam G., Heffler, Enrico, Hew, Mark, Iwanaga, Takashi, Jackson, David J., Kocks, Janwillem W.H., Kallieri, Maria, Bruce Ko, Hsin-Kuo, Koh, Mariko Siyue, Larenas-Linnemann, Désirée, Lehtimäki, Lauri A., Loukides, Stelios, Lugogo, Njira, Maspero, Jorge, Papaioannou, Andriana I., Perez-de-Llano, Luis, Pitrez, Paulo Márcio, Popov, Todor A., Rasmussen, Linda M., Rhee, Chin Kook, Sadatsafavi, Mohsen, Schmid, Johannes, Siddiqui, Salman, Taillé, Camille, Taube, Christian, Torres-Duque, Carlos A., Ulrik, Charlotte, Upham, John W., Wang, Eileen, Wechsler, Michael E., Bulathsinhala, Lakmini, Carter, Victoria, Chaudhry, Isha, Eleangovan, Neva, Hosseini, Naeimeh, Rowlands, Mari-Anne, Price, David B., and van Boven, Job F.M.
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- 2022
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19. Real‐world biologics response and super‐response in the International Severe Asthma Registry cohort.
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Denton, Eve, Hew, Mark, Peters, Matthew J., Upham, John W., Bulathsinhala, Lakmini, Tran, Trung N., Martin, Neil, Bergeron, Celine, Al‐Ahmad, Mona, Altraja, Alan, Larenas‐Linnemann, Désirée, Murray, Ruth, Celis‐Preciado, Carlos Andrés, Al‐Lehebi, Riyad, Belhassen, Manon, Bhutani, Mohit, Bosnic‐Anticevich, Sinthia Z., Bourdin, Arnaud, Brusselle, Guy G., and Busby, John
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FORCED expiratory volume ,ASTHMATICS ,RANDOMIZED controlled trials ,BIOTHERAPY ,MONOCLONAL antibodies - Abstract
Background: Biologic asthma therapies reduce exacerbations and long‐term oral corticosteroids (LTOCS) use in randomized controlled trials (RCTs); however, there are limited data on outcomes among patients ineligible for RCTs. Hence, we investigated responsiveness to biologics in a real‐world population of adults with severe asthma. Methods: Adults in the International Severe Asthma Registry (ISAR) with ≥24 weeks of follow‐up were grouped into those who did, or did not, initiate biologics (anti‐IgE, anti‐IL5/IL5R, anti‐IL4/13). Treatment responses were examined across four domains: forced expiratory volume in 1 second (FEV1) increase by ≥100 mL, improved asthma control, annualized exacerbation rate (AER) reduction ≥50%, and any LTOCS dose reduction. Super‐response criteria were: FEV1 increase by ≥500 mL, new well‐controlled asthma, no exacerbations, and LTOCS cessation or tapering to ≤5 mg/day. Results: 5.3% of ISAR patients met basic RCT inclusion criteria; 2116/8451 started biologics. Biologic initiators had worse baseline impairment than non‐initiators, despite having similar biomarker levels. Half or more of initiators had treatment responses: 59% AER reduction, 54% FEV1 increase, 49% improved control, 49% reduced LTOCS, of which 32%, 19%, 30%, and 39%, respectively, were super‐responses. Responses/super‐responses were more frequent in biologic initiators than in non‐initiators; nevertheless, ~40–50% of initiators did not meet response criteria. Conclusions: Most patients with severe asthma are ineligible for RCTs of biologic therapies. Biologics are initiated in patients who have worse baseline impairments than non‐initiators despite similar biomarker levels. Although biologic initiators exhibited clinical responses and super‐responses in all outcome domains, 40–50% did not meet the response criteria. [ABSTRACT FROM AUTHOR]
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- 2024
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20. Exploring Definitions and Predictors of Severe Asthma Clinical Remission after Biologic Treatment in Adults.
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Perez-de-Llano, Luis, Scelo, Ghislaine, Tran, Trung N., Le, Tham T., Fagerås, Malin, Cosio, Borja G., Peters, Matthew, Pfeffer, Paul E., Al-Ahmad, Mona, Al-Lehebi, Riyad O., Altraja, Alan, Bergeron, Celine, Bjermer, Leif H., Bjerrum, Anne S., Bulathsinhala, Lakmini, Busby, John, Cano Rosales, Diana J., Canonica, Giorgio W., Carter, Victoria A., and Charriot, Jeremy
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DISEASE remission ,ODDS ratio ,ASTHMA ,LUNGS ,LONGITUDINAL method - Abstract
Rationale: There is no consensus on criteria to include in an asthma remission definition in real life. Factors associated with achieving remission after biologic initiation remain poorly understood. Objectives: To quantify the proportion of adults with severe asthma achieving multidomain-defined remission after biologic initiation and identify prebiologic characteristics associated with achieving remission that may be used to predict it. Methods: This was a longitudinal cohort study using data from 23 countries from the International Severe Asthma Registry. Four asthma outcome domains were assessed in the 1 year before and after biologic initiation. A priori–defined remission cutoffs were: 0 exacerbations/yr, no long-term oral corticosteroid (LTOCS), partly/well-controlled asthma, and percent predicted FEV
1 ⩾ 80%. Remission was defined using two (exacerbations + LTOCS), three (+control or +lung function), and four of these domains. The association between prebiologic characteristics and postbiologic remission was assessed by multivariable analysis. Measurements and Main Results: A total of 50.2%, 33.5%, 25.8%, and 20.3% of patients met criteria for two-, three- (+control), three- (+lung function), and four-domain remission, respectively. The odds of achieving four-domain remission decreased by 15% for every additional 10 years of asthma duration (odds ratio, 0.85; 95% confidence interval, 0.73–1.00). The odds of remission increased in those with fewer exacerbations per year, lower LTOCS daily dose, better control, and better lung function before biologic initiation. Conclusions: One in five patients achieved four-domain remission within 1 year of biologic initiation. Patients with less severe impairment and shorter asthma duration at initiation had a greater chance of achieving remission after biologic treatment, indicating that biologic treatment should not be delayed if remission is the goal. [ABSTRACT FROM AUTHOR]- Published
- 2024
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21. Ethnic Differences in Severe Asthma Clinical Care and Outcomes: An Analysis of United Kingdom Primary and Specialist Care
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Busby, John, Heaney, Liam G., Brown, Thomas, Chaudhuri, Rekha, Dennison, Paddy, Gore, Robin, Jackson, David J., Mansur, Adel H., Menzies-Gow, Andrew, Message, Simon, Niven, Rob, Patel, Mitesh, Price, David, Siddiqui, Salman, Stone, Robert, and Pfeffer, Paul E.
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- 2022
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22. The inflammatory profile of exacerbations in patients with severe refractory eosinophilic asthma receiving mepolizumab (the MEX study): a prospective observational study
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McDowell, P Jane, Diver, Sarah, Yang, Freda, Borg, Catherine, Busby, John, Brown, Vanessa, Shrimanker, Rahul, Cox, Ciara, Brightling, Christopher E, Chaudhuri, Rekha, Pavord, Ian D, Heaney, Liam G, Wise, Christopher, McAnally, Christine, Drain, Stephen, Mistry, Vijay, Arnold, Hannah, Micieli, Claudia, Monterio, William, Jones, Marc, Ellis, Hattie, Thulborn, Samantha, Cheyne, Linda, Ramsey, Esther, Howes, Sarah, Bourne, Michelle, Thorton, Tracy, Edwards, Sarah, Evans, Helen, Smith, Steven, and Grandison, Tracyanne
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- 2021
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23. Factors Associated with Frequent Exacerbations in the UK Severe Asthma Registry
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Patel, Mitesh, Gore, Robin, Brown, Thomas, Vyas, Aashish, Subramanian, Deepak, Yang, Freda, Busby, John, Heaney, Liam G., Menzies-Gow, Andrew, Pfeffer, Paul E., Jackson, David J., Mansur, Adel H., Siddiqui, Salman, Brightling, Christopher E., Niven, Robert, Thomson, Neil C., and Chaudhuri, Rekha
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- 2021
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24. Potential Severe Asthma Hidden in UK Primary Care
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Ryan, Dermot, Heatley, Heath, Heaney, Liam G., Jackson, David J., Pfeffer, Paul E., Busby, John, Menzies-Gow, Andrew N., Jones, Rupert, Tran, Trung N., Al-Ahmad, Mona, Backer, Vibeke, Belhassen, Manon, Bosnic-Anticevich, Sinthia, Bourdin, Arnaud, Bulathsinhala, Lakmini, Carter, Victoria, Chaudhry, Isha, Eleangovan, Neva, FitzGerald, J. Mark, Gibson, Peter G., Hosseini, Naeimeh, Kaplan, Alan, Murray, Ruth B., Rhee, Chin Kook, Van Ganse, Eric, and Price, David B.
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- 2021
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25. Cognitive and psychiatric symptom trajectories 2–3 years after hospital admission for COVID-19: a longitudinal, prospective cohort study in the UK
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Taquet, Maxime, Skorniewska, Zuzanna, De Deyn, Thomas, Hampshire, Adam, Trender, William R, Hellyer, Peter J, Chalmers, James D, Ho, Ling-Pei, Horsley, Alex, Marks, Michael, Poinasamy, Krisnah, Raman, Betty, Leavy, Olivia C, Richardson, Matthew, Elneima, Omer, McAuley, Hamish J C, Shikotra, Aarti, Singapuri, Amisha, Sereno, Marco, Saunders, Ruth M, Harris, Victoria C, Rogers, Natalie, Houchen-Wolloff, Linzy, Greening, Neil J, Mansoori, Parisa, Harrison, Ewen M, Docherty, Annemarie B, Lone, Nazir I, Quint, Jennifer, Brightling, Christopher E, Wain, Louise V, Evans, Rachael A, Geddes, John R, Harrison, Paul J, Lone, Nazir, Baillie, Kenneth, Pairo-Castineira, Erola, Avramidis, Nikos, Wain, Louise, Guillen-Guio, Beatriz, Leavy, Olivia, Jones, S, Armstrong, Lisa, Hairsine, Brigid, Henson, Helen, Kurasz, Claire, Shaw, Alison, Shenton, Liz, Dobson, Hannah, Dell, Amanda, Fairbairn, Sara, Hawkings, Nancy, Haworth, Jill, Hoare, Michaela, Lewis, Victoria, Lucey, Alice, Mallison, Georgia, Nassa, Heeah, Pennington, Chris, Price, Andrea, Price, Claire, Storrie, Andrew, Willis, Gemma, Young, Susan, Poinasamy, Krisnah, Walker, Samantha, Jarrold, Ian, Rawlik, Konrad, Sanderson, Amy, Chong-James, K, David, C, James, W Y, Pfeffer, Paul, Zongo, O, Martineau, Adrian, Manisty, C, Armour, Cherie, Brown, Vanessa, Busby, John, Connolly, Bronwen, Craig, Thelma, Drain, Stephen, Heaney, Liam, King, Bernie, Magee, Nick, Major, E, McAulay, Danny, McGarvey, Lorcan, McGinness, Jade, Peto, Tunde, Stone, Roisin, Bolger, Annette, Davies, Ffyon, Haggar, Ahmed, Lewis, Joanne, Lloyd, Arwel, Manley, R, McIvor, Emma, Menzies, Daniel, Roberts, K, Saxon, W, Southern, David, Subbe, Christian, Whitehead, Victoria, Bularga, Anda, Mills, Nicholas, Dawson, Joy, El-Taweel, Hosni, Robinson, Leanne, Brear, Lucy, Regan, Karen, Saralaya, Dinesh, Storton, Kim, Amoils, Shannon, Bermperi, Areti, Cruz, Isabel, Dempsey, K, Elmer, Anne, Fuld, Jonathon, Jones, H, Jose, Sherly, Marciniak, Stefan, Parkes, M, Ribeiro, Carla, Taylor, Jessica, Toshner, Mark, Watson, L, Worsley, J, Broad, Lauren, Evans, Teriann, Haynes, Matthew, Jones, L, Knibbs, Lucy, McQueen, Alison, Oliver, Catherine, Paradowski, Kerry, Sabit, Ramsey, Williams, Jenny, Jones, Ian, Milligan, Lea, Harris, Edward, Sampson, Claire, Davies, Ellie, Evenden, Cerys, Hancock, Alyson, Hancock, Kia, Lynch, Ceri, Rees, Meryl, Roche, Lisa, Stroud, Natalie, Thomas-Woods, T, Heller, Simon, Chalder, Trudie, Shah, Kamini, Robertson, Elizabeth, Young, Bob, Babores, Marta, Holland, Maureen, Keenan, Natalie, Shashaa, Sharlene, Wassall, Helen, Austin, Liam, Beranova, Eva, Cosier, Tracey, Deery, Joanne, Hazelton, Tracy, Price, Carly, Ramos, Hazel, Solly, Reanne, Turney, Sharon, Weston, Heather, Coughlan, Eamon, Ralser, Markus, Pearce, Lorraine, Pugmire, S, Stoker, Wendy, Wilson, Ann, McCormick, W, Fraile, Eva, Ugoji, Jacinta, Aguilar Jimenez, Laura, Arbane, Gill, Betts, Sarah, Bisnauthsing, Karen, Dewar, A, Hart, Nicholas, Kaltsakas, G, Kerslake, Helen, Magtoto, Murphy, Marino, Philip, Martinez, L M, Ostermann, Marlies, Rossdale, Jennifer, Solano, Teresa, Alvarez Corral, Maria, Arias, Ava Maria, Bevan, Emily, Griffin, Denise, Martin, Jane, Owen, J, Payne, Sheila, Prabhu, A, Reed, Annabel, Storrar, Will, Williams, Nick, Wrey Brown, Caroline, Burdett, Tracy, Featherstone, James, Lawson, Cathy, Layton, Alison, Mills, Clare, Stephenson, Lorraine, Ellis, Yvette, Atkin, Paul, Brindle, K, Crooks, Michael, Drury, Katie, Easom, Nicholas, Flockton, Rachel, Holdsworth, L, Richards, A, Sykes, D L, Thackray-Nocera, Susannah, Wright, C, Coetzee, S, Davies, Kim, Hughes, Rachel Ann, Loosley, Ronda, McGuinness, Heather, Mohamed, Abdelrahman, O'Brien, Linda, Omar, Zohra, Perkins, Emma, Phipps, Janet, Ross, Gavin, Taylor, Abigail, Tench, Helen, Wolf-Roberts, Rebecca, Burden, L, Calvelo, Ellen, Card, Bethany, Carr, Caitlin, Chilvers, Edwin, Copeland, Donna, Cullinan, P, Daly, Patrick, Evison, Lynsey, Fayzan, Tamanah, Gordon, Hussain, Haq, Sulaimaan, Jenkins, Gisli, King, Clara, Kon, Onn Min, March, Katherine, Mariveles, Myril, McLeavey, Laura, Mohamed, Noura, Moriera, Silvia, Munawar, Unber, Nunag, Jose Lloyd, Nwanguma, Uchechi, Orriss-Dib, Lorna, Ross, Alexandra, Roy, Maura, Russell, Emily, Samuel, Katherine, Schronce, J, Simpson, Neil, Tarusan, Lawrence, Thomas, David, Wood, Chloe, Yasmin, Najira, Altmann, Danny, Howard, Luke, Johnston, Desmond, Lingford-Hughes, Anne, Man, William, Mitchell, Jane, Molyneaux, Philip, Nicolaou, Christos, O'Regan, D P, Price, L, Quint, Jenni, Smith, David, Thwaites, Ryan, Valabhji, Jonathon, Walsh, Simon, Efstathiou, Claudia, Liew, Felicity, Frankel, Anew, Lightstone, Liz, McAdoo, Steve, Wilkins, Martin, Willicombe, Michelle, Touyz, R, Guerdette, Anne-Marie, Hewitt, Melanie, Reddy, R, Warwick, Katie, White, Sonia, McMahon, Aisling, Adeyemi, Oluwaseun, Adrego, Rita, Assefa-Kebede, Hosanna, Breeze, Jonathon, Byrne, S, Dulawan, Pearl, Hoare, Amy, Jolley, Caroline, Knighton, Abigail, Patale, Sheetal, Peralta, Ida, Powell, Natassia, Ramos, Albert, Shevket, K, Speranza, Fabio, Te, Amelie, Malim, M, Bramham, Kate, Brown, M, Ismail, Khalida, Nicholson, Tim, Pariante, Carmen, Sharpe, Claire, Wessely, Simon, Whitney, J, Shah, Ajay, Chiribiri, A, O'Brien, C, Hayday, A, Ashworth, Andrew, Beirne, Paul, Clarke, Jude, Coupland, C, Dalton, Matthhew, Favager, Clair, Glossop, Jodie, Greenwood, John, Hall, Lucy, Hardy, Tim, Humphries, Amy, Murira, Jennifer, Peckham, Dan, Plein, S, Rangeley, Jade, Saalmink, Gwen, Tan, Ai Lyn, Wade, Elaine, Whittam, Beverley, Window, Nicola, Woods, Janet, Coakley, G, Turtle, Lance, Allerton, Lisa, Allt, Ann Marie, Beadsworth, M, Berridge, Anthony, Brown, Jo, Cooper, Shirley, Cross, Andy, Defres, Sylviane, Dobson, S L, Earley, Joanne, French, N, Greenhalf, William, Hainey, Kera, Hardwick, Hayley, Hawkes, Jenny, Highett, Victoria, Kaprowska, Sabina, Key, Angela, Lavelle-Langham, Lara, Lewis-Burke, N, Madzamba, Gladys, Malein, Flora, Marsh, Sophie, Mears, Chloe, Melling, Lucy, Noonan, Matthew, Poll, L, Pratt, James, Richardson, Emma, Rowe, Anna, Semple, Calum, Shaw, Victoria, Tripp, K A, Wajero, Lilian, Williams-Howard, S A, Wootton, Dan, Wyles, J, Diwanji, Shalin, Gurram, Sambasivarao, Papineni, Padmasayee, Quaid, Sheena, Tiongson, Gerlynn, Watson, Ekaterina, Briggs, Andrew, Marks, Michael, Hastie, Claire, Rogers, Natalie, Smith, Nikki, Stensel, David, Bishop, Lettie, McIvor, Katherine, Rivera-Ortega, Pilar, Al-Sheklly, Bashar, Avram, Cristina, Blaikely, John, Buch, M, Choudhury, N, Faluyi, David, Felton, T, Gorsuch, T, Hanley, Neil, Horsley, Alex, Hussell, Tracy, Kausar, Zunaira, Odell, Natasha, Osbourne, Rebecca, Piper Hanley, Karen, Radhakrishnan, K, Stockdale, Sue, Kabir, Thomas, Scott, Janet, Stewart, Iain, Openshaw, Peter, Burn, David, Ayoub, A, Brown, J, Burns, G, Davies, Gareth, De Soyza, Anthony, Echevarria, Carlos, Fisher, Helen, Francis, C, Greenhalgh, Alan, Hogarth, Philip, Hughes, Joan, Jiwa, Kasim, Jones, G, MacGowan, G, Price, D, Sayer, Avan, Simpson, John, Tedd, H, Thomas, S, West, Sophie, Witham, M, Wright, S, Young, A, McMahon, Michael, Neill, Paula, Anderson, David, Basu, Neil, Bayes, Hannah, Brown, Ammani, Dougherty, Andrew, Fallon, K, Gilmour, L, Grieve, D, Mangion, K, Morrow, A, Sykes, R, Berry, Colin, McInnes, I B, Scott, Kathryn, Barrett, Fiona, Donaldson, A, Sage, Beth, Bell, Murdina, Brown, Angela, Brown, M, Hamil, R, Leitch, Karen, Macliver, L, Patel, Manish, Quigley, Jackie, Smith, Andrew, Welsh, B, Choudhury, Gaunab, Clohisey, S, Deans, Andrew, Docherty, Annemarie, Furniss, J, Harrison, Ewen, Kelly, S, Sheikh, Aziz, Chalmers, James, Connell, David, Deas, C, Elliott, Anne, George, J, Mohammed, S, Rowland, J, Solstice, AR, Sutherland, Debbie, Tee, Caroline, Bunker, Jenny, Gill, Rhyan, Nathu, Rashmita, Holmes, Katie, Adamali, H, Arnold, David, Barratt, Shaney, Dipper, A, Dunn, Sarah, Maskell, Nick, Morley, Anna, Morrison, Leigh, Stadon, Louise, Waterson, Samuel, Welch, H, Jayaraman, Bhagy, Light, Tessa, Vogiatzis, Ioannis, Almeida, Paula, Bolton, Charlotte, Hosseini, Akram, Matthews, Laura, Needham, Robert, Shaw, Karen, Thomas, Andrew, Bonnington, J, Chrystal, Melanie, Dupont, Catherine, Greenhaff, Paul, Gupta, Ayushman, Jang, W, Linford, S, Nikolaidis, Athanasios, Prosper, Sabrina, Burns, A, Kanellakis, N, Ferreira, V, Nikolaidou, C, Xie, C, Ainsworth, Mark, Alamoudi, Asma, Bloss, Angela, Carter, Penny, Cassar, M, Chen, Jin, Conneh, Florence, Dong, T, Evans, Ranuromanana, Fraser, Emily, Geddes, John, Gleeson, F, Harrison, Paul, Havinden-Williams, May, Ho, Ling Pei, Jezzard, P, Koychev, Ivan, Kurupati, Prathiba, McShane, H, Megson, Clare, Neubauer, Stefan, Nicoll, Debby, Ogg, G, Pacpaco, Edmund, Pavlides, M, Peng, Yanchun, Petousi, Nayia, Pimm, John, Rahman, Najib, Raman, Betty, Rowland, M J, Saunders, Kathryn, Sharpe, Michael, Talbot, Nick, Tunnicliffe, E M, Korszun, Ania, Kerr, Steven, Barker, R E, Cristiano, Daniele, Dormand, N, George, P, Gummadi, Mahitha, Kon, S, Liyanage, Kamal, Nolan, C M, Patel, B, Patel, Suhani, Polgar, Oliver, Price, L, Shah, P, Singh, Suver, Walsh, J A, Gibbons, Michael, Ahmad, Shanaz, Brill, Simon, Hurst, John, Jarvis, Hannah, Lim, Lai, Mandal, S, Matila, Darwin, Olaosebikan, Olaoluwa, Singh, Claire, Laing, C, Baxendale, Helen, Garner, Lucie, Johnson, C, Mackie, J, Michael, Alice, Newman, J, Pack, Jamie, Paques, K, Parfrey, H, Parmar, J, Reddy, A, Halling-Brown, Mark, Dark, P, Diar-Bakerly, Nawar, Evans, D, Hardy, E, Harvey, Alice, Holgate, D, Knight, Sean, Mairs, N, Majeed, N, McMorrow, L, Oxton, J, Pendlebury, Jessica, Summersgill, C, Ugwuoke, R, Whittaker, S, Matimba-Mupaya, Wadzanai, Strong-Sheldrake, Sophia, Chowienczyk, Phillip, Bagshaw, J, Begum, M, Birchall, K, Butcher, Robyn, Carborn, H, Chan, Flora, Chapman, Kerry, Cheng, Yutung, Chetham, Luke, Clark, Cameron, Coburn, Zach, Cole, Joby, Dixon, Myles, Fairman, Alexandra, Finnigan, J, Foot, H, Foote, David, Ford, Amber, Gregory, Rebecca, Harrington, Kate, Haslam, L, Hesselden, L, Hockridge, J, Holbourn, Ailsa, Holroyd-Hind, B, Holt, L, Howell, Alice, Hurditch, E, Ilyas, F, Jarman, Claire, Lawrie, Allan, Lee, Ju Hee, Lee, Elvina, Lenagh, Rebecca, Lye, Alison, Macharia, Irene, Marshall, M, Mbuyisa, Angeline, McNeill, J, Megson, Sharon, Meiring, J, Milner, L, Misra, S, Newell, Helen, Newman, Tom, Norman, C, Nwafor, Lorenza, Pattenadk, Dibya, Plowright, Megan, Porter, Julie, Ravencroft, Phillip, Roddis, C, Rodger, J, Rowland-Jones, Sarah, Saunders, Peter, Sidebottom, J, Smith, Jacqui, Smith, Laurie, Steele, N, Stephens, G, Stimpson, R, Thamu, B, Thompson, A. A. Roger, Tinker, N, Turner, Kim, Turton, Helena, Wade, Phillip, Walker, S, Watson, James, Wilson, Imogen, Zawia, Amira, Allsop, Lynne, Bennett, Kaytie, Buckley, Phil, Flynn, Margaret, Gill, Mandy, Goodwin, Camelia, Greatorex, M, Gregory, Heidi, Heeley, Cheryl, Holloway, Leah, Holmes, Megan, Hutchinson, John, Kirk, Jill, Lovegrove, Wayne, Sewell, Terri Ann, Shelton, Sarah, Sissons, D, Slack, Katie, Smith, Susan, Sowter, D, Turner, Sarah, Whitworth, V, Wynter, Inez, Tomlinson, Johanne, Warburton, Louise, Painter, Sharon, Palmer, Sue, Redwood, Dawn, Tilley, Jo, Vickers, Carinna, Wainwright, Tania, Breen, G, Hotopf, M, Aul, Raminder, Forton, D, Ali, Mariam, Dunleavy, A, Mencias, Mark, Msimanga, N, Samakomva, T, Siddique, Sulman, Tavoukjian, Vera, Teixeira, J, Ahmed, Rubina, Francis, Richard, Connor, Lynda, Cook, Amanda, Davies, Gwyneth, Rees, Tabitha, Thaivalappil, Favas, Thomas, Caradog, McNarry, M, Williams, N, Lewis, Keir, Coulding, Martina, Jones, Heather, Kilroy, Susan, McCormick, Jacqueline, McIntosh, Jerome, Turner, Victoria, Vere, Joanne, Butt, Al-Tahoor, Savill, Heather, Kon, Samantha, Landers, G, Lota, Harpreet, Portukhay, Sofiya, Nasseri, Mariam, Daniels, Alison, Hormis, Anil, Ingham, Julie, Zeidan, Lisa, Chablani, Manish, Osborne, Lynn, Aslani, Shahab, Banerjee, Amita, Batterham, R, Baxter, Gabrielle, Bell, Robert, David, Anthony, Denneny, Emma, Hughes, Alun, Lilaonitkul, W, Mehta, P, Pakzad, Ashkan, Rangelov, Bojidar, Williams, B, Willoughby, James, Xu, Moucheng, Ahwireng, Nyarko, Bang, Dongchun, Basire, Donna, Brown, Jeremy, Chambers, Rachel, Checkley, A, Evans, R, Heightman, M, Hillman, T, Jacob, Joseph, Jastrub, Roman, Lipman, M, Logan, S, Lomas, D, Merida Morillas, Marta, Plant, Hannah, Porter, Joanna, Roy, K, Wall, E, Treibel, T, Ahmad Haider, N, Atkin, Catherine, Baggott, Rhiannon, Bates, Michelle, Botkai, A, Casey, Anna, Cooper, B, Dasgin, Joanne, Dawson, Camilla, Draxlbauer, Katharine, Gautam, N, Hazeldine, J, Hiwot, T, Holden, Sophie, Isaacs, Karen, Jackson, T, Kamwa, Vicky, Lewis, D, Lord, Janet, Madathil, S, McGee, C, Mcgee, K, Neal, Aoife, Newton-Cox, Alex, Nyaboko, Joseph, Parekh, Dhruv, Peterkin, Z, Qureshi, H, Ratcliffe, Liz, Sapey, Elizabeth, Short, J, Soulsby, Tracy, Stockley, J, Suleiman, Zehra, Thompson, Tamika, Ventura, Maximina, Walder, Sinead, Welch, Carly, Wilson, Daisy, Yasmin, S, Yip, Kay Por, Chaudhuri, N, Childs, Caroline, Djukanovic, R, Fletcher, S, Harvey, Matt, Jones, Mark, Marouzet, Elizabeth, Marshall, B, Samuel, Reena, Sass, T, Wallis, Tim, Wheeler, Helen, Steeds, R, Beckett, Paul, Dickens, Caroline, Nanda, Uttam, Aljaroof, M, Armstrong, Natalie, Arnold, H, Aung, Hnin, Bakali, Majda, Bakau, M, Baldry, E, Baldwin, Molly, Bourne, Charlotte, Bourne, Michelle, Brightling, Chris, Brunskill, Nigel, Cairns, P, Carr, Liesel, Charalambou, Amanda, Christie, C, Davies, Melanie, Daynes, Enya, Diver, Sarah, Dowling, Rachael, Edwards, Sarah, Edwardson, C, Elneima, Omer, Evans, H, Evans, Rachael, Finch, J, Glover, Sarah, Goodman, Nicola, Gooptu, Bibek, Greening, Neil, Hadley, Kate, Haldar, Pranab, Hargadon, Beverley, Harris, Victoria, Houchen-Wolloff, Linzy, Ibrahim, W, Ingram, L, Khunti, Kamlesh, Lea, A, Lee, D, McAuley, Hamish, McCann, Gerry, McCourt, P, Mcnally, Teresa, Mills, George, Monteiro, Will, Pareek, Manish, Parker, S, Prickett, Anne, Qureshi, I N, Rowland, A, Russell, Richard, Sereno, Marco, Shikotra, Aarti, Siddiqui, Salman, Singapuri, Ananga, Singh, Sally, Skeemer, J, Soares, M, Stringer, E, Thornton, T, Tobin, Martin, Ward, T J C, Woodhead, F, Yates, Tom, Yousuf, A J, Broome, Mattew, McArdle, Paul, Thickett, David, Upthegrove, Rachel, Wilkinson, Dan, Moss, Paul, Wraith, David, Evans, Jonathon, Bullmore, Ed, Heeney, Jonathon, Langenberg, Claudia, Schwaeble, William, Summers, Charlotte, Weir McCall, J, Adeloye, Davies, Newby, D E, Pius, Riinu, Rudan, Igor, Shankar-Hari, Manu, Sudlow, Catherine, Thorpe, Mat, Walmsley, Sarah, Zheng, Bang, Allan, Louise, Ballard, Clive, McGovern, Andrew, Dennis, J, Cavanagh, Jonathon, MacDonald, S, O'Donnell, Kate, Petrie, John, Sattar, Naveed, Spears, Mark, Guthrie, Elspeth, Henderson, Max, Allen, Richard, Bingham, Michelle, Brugha, Terry, Finney, Selina, Free, Rob, Jones, Don, Lawson, Claire, Lucy, Gardiner, Moss, Alistair, Mukaetova-Ladinska, Elizabeta, Novotny, Petr, Overton, Charlotte, Pearl, John, Plekhanova, Tatiana, Richardson, M, Samani, Nilesh, Sargant, Jack, Sharma, M, Steiner, Mike, Taylor, Chris, Terry, Sarah, Tong, C, Turner, E, Wormleighton, J, Zhao, Bang, Ntotsis, Kimon, Saunders, Ruth, Lozano-Rojas, Daniel, Goemans, Anne, Cuthbertson, D, Kemp, G, McArdle, Anne, Michael, Benedict, Reynolds, Will, Spencer, Lisa, Vinson, Ben, Ashworth, M, Abel, Kathryn, Chinoy, H, Deakin, Bill, Harvie, M, Miller, C A, Stanel, Stefan, Barran, Perdita, Trivedi, Drupad, McAllister-Williams, Hamish, Paddick, Stella-Maria, Rostron, Anthony, Taylor, John Paul, Baguley, David, Coleman, Chris, Cox, E, Fabbri, Laura, Francis, Susan, Hall, Ian, Hufton, E, Johnson, Simon, Khan, Fasih, Kitterick, Paaig, Morriss, Richard, Selby, Nick, Wright, Louise, Antoniades, Charalambos, Bates, A, Beggs, M, Bhui, Kamaldeep, Breeze, Katie, Channon, K M, Clark, David, Fu, X, Husain, Masud, Li, X, Lukaschuk, E, McCracken, Celeste, McGlynn, K, Menke, R, Motohashi, K, Nichols, T E, Ogbole, Godwin, Piechnik, S, Propescu, I, Propescu, J, Samat, A A, Sanders, Z B, Sigfrid, Louise, Webster, M, Kingham, Lucy, Klenerman, Paul, Lamlum, Hanan, Taquet, Maxime, Carson, G, Finnigan, L, Saunders, Laura, Wild, James, Calder, P C, Huneke, Nathan, Simons, Gemma, Baldwin, David, Bain, Steve, Daines, Luke, Bright, E, Crisp, P, Dharmagunawardena, Ruvini, Stern, M, Bailey, Elisabeth, Reddington, Anne, Wight, Andrew, Ashish, A, Cooper, Josh, Robinson, Emma, Broadley, Andrew, Barman, Laura, Brookes, Claire, Elliott, K, Griffiths, L, Guy, Zoe, Howard, Kate, Ionita, Diana, Redfearn, Heidi, Sarginson, Carol, and Turnbull, Alison
- Abstract
COVID-19 is known to be associated with increased risks of cognitive and psychiatric outcomes after the acute phase of disease. We aimed to assess whether these symptoms can emerge or persist more than 1 year after hospitalisation for COVID-19, to identify which early aspects of COVID-19 illness predict longer-term symptoms, and to establish how these symptoms relate to occupational functioning.
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- 2024
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26. Composite type-2 biomarker strategy versus a symptom–risk-based algorithm to adjust corticosteroid dose in patients with severe asthma: a multicentre, single-blind, parallel group, randomised controlled trial
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Adcock, Ian M, Azim, Adnam, Bellamy, Mary, Borg, Catherine, Bourne, Michelle, Connolly, Clare, Costello, Richard W, Corrigan, Chris J, Davies, Sarah, Davies, Gareth, Chung, Kian F, Gainsborough, Gabrielle, Grandison, Traceyanne, Hargadon, Beverley, Horn, Avril, Hudson, Val, Jackson, David, Johnston, Sebastian, Jones, Geraldine, McCourt, Paula, Nunez, Maria, Shaw, Dominic E, Smith, Katherine, Solis, Joel, Stone, Roisin, Yang, Freda, Heaney, Liam G, Busby, John, Hanratty, Catherine E, Djukanovic, Ratko, Woodcock, Ashley, Walker, Samantha M, Hardman, Timothy C, Arron, Joseph R, Choy, David F, Bradding, Peter, Brightling, Christopher E, Chaudhuri, Rekha, Cowan, Douglas C, Mansur, Adel H, Fowler, Stephen J, Niven, Robert M, Howarth, Peter H, Lordan, James L, Menzies-Gow, Andrew, Harrison, Tim W, Robinson, Douglas S, Holweg, Cecile T J, Matthews, John G, and Pavord, Ian D
- Published
- 2021
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27. Association between pre-biologic T2-biomarker combinations and response to biologics in patients with severe asthma
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Porsbjerg, Celeste M., Townend, John, Bergeron, Celine, Christoff, George C., Katsoulotos, Gregory P., Larenas-Linnemann, Desiree, Tran, Trung N., Al-Lehebi, Riyad, Bosnic-Anticevich, Sinthia Z., Busby, John, Hew, Mark, Kostikas, Konstantinos, Papadopoulos, Nikolaos G., Pfeffer, Paul E., Popov, Todor A., Rhee, Chin Kook, Sadatsafavi, Mohsen, Tsai, Ming-Ju, Ulrik, Charlotte Suppli, Al-Ahmad, Mona, Altraja, Alan, Beastall, Aaron, Bulathsinhala, Lakmini, Carter, Victoria, Cosio, Borja G., Fletton, Kirsty, Hansen, Susanne, Heaney, Liam G., Hubbard, Richard B., Kuna, Piotr, Murray, Ruth B., Nagano, Tatsuya, Pini, Laura, Rosales, Diana Jimena Cano, Schleich, Florence, Wechsler, Michael E., Amaral, Rita, Bourdin, Arnaud, Brusselle, Guy G., Chen, Wenjia, Chung, Li Ping, Denton, Eve, Fonseca, Joao A., Hoyte, Flavia, Jackson, David J., Katial, Rohit, Kirenga, Bruce J., Koh, Mariko Siyue, Lawkiedraj, Agnieszka, Lehtimaki, Lauri, Liew, Mei Fong, Mahboub, Bassam, Martin, Neil, Menzies-Gow, Andrew N., Pang, Pee Hwee, Papaioannou, Andriana I., Patel, Pujan H., Perez-De-Llano, Luis, Peters, Matthew J., Ricciardi, Luisa, Rodriguez-Caceres, Bellanid, Solarte, Ivan, Tay, Tunn Ren, Torres-Duque, Carlos A., Wang, Eileen, Zappa, Martina, Abisheganaden, John, Assing, Karin Dahl, Costello, Richard W., Gibson, Peter G., Heffler, Enrico, Maspero, Jorge, Nicola, Stefania, Steve, Diahn-Warng Perng, Puggioni, Francesca, Salvi, Sundeep, Sheu, Chau-Chyun, Sirena, Concetta, Taille, Camille, Tan, Tze Lee, Bjermer, Leif, Canonica, Giorgio Walter, Iwanaga, Takashi, Jimenez-Maldonado, Libardo, Taube, Christian, Brussino, Luisa, Price, David B., Porsbjerg, Celeste M., Townend, John, Bergeron, Celine, Christoff, George C., Katsoulotos, Gregory P., Larenas-Linnemann, Desiree, Tran, Trung N., Al-Lehebi, Riyad, Bosnic-Anticevich, Sinthia Z., Busby, John, Hew, Mark, Kostikas, Konstantinos, Papadopoulos, Nikolaos G., Pfeffer, Paul E., Popov, Todor A., Rhee, Chin Kook, Sadatsafavi, Mohsen, Tsai, Ming-Ju, Ulrik, Charlotte Suppli, Al-Ahmad, Mona, Altraja, Alan, Beastall, Aaron, Bulathsinhala, Lakmini, Carter, Victoria, Cosio, Borja G., Fletton, Kirsty, Hansen, Susanne, Heaney, Liam G., Hubbard, Richard B., Kuna, Piotr, Murray, Ruth B., Nagano, Tatsuya, Pini, Laura, Rosales, Diana Jimena Cano, Schleich, Florence, Wechsler, Michael E., Amaral, Rita, Bourdin, Arnaud, Brusselle, Guy G., Chen, Wenjia, Chung, Li Ping, Denton, Eve, Fonseca, Joao A., Hoyte, Flavia, Jackson, David J., Katial, Rohit, Kirenga, Bruce J., Koh, Mariko Siyue, Lawkiedraj, Agnieszka, Lehtimaki, Lauri, Liew, Mei Fong, Mahboub, Bassam, Martin, Neil, Menzies-Gow, Andrew N., Pang, Pee Hwee, Papaioannou, Andriana I., Patel, Pujan H., Perez-De-Llano, Luis, Peters, Matthew J., Ricciardi, Luisa, Rodriguez-Caceres, Bellanid, Solarte, Ivan, Tay, Tunn Ren, Torres-Duque, Carlos A., Wang, Eileen, Zappa, Martina, Abisheganaden, John, Assing, Karin Dahl, Costello, Richard W., Gibson, Peter G., Heffler, Enrico, Maspero, Jorge, Nicola, Stefania, Steve, Diahn-Warng Perng, Puggioni, Francesca, Salvi, Sundeep, Sheu, Chau-Chyun, Sirena, Concetta, Taille, Camille, Tan, Tze Lee, Bjermer, Leif, Canonica, Giorgio Walter, Iwanaga, Takashi, Jimenez-Maldonado, Libardo, Taube, Christian, Brussino, Luisa, and Price, David B.
- Abstract
Background: To date, studies investigating the association between pre-biologic biomarker levels and post-biologic outcomes have been limited to single biomarkers and assessment of biologic efficacy from structured clinical trials. Aim: To elucidate the associations of pre-biologic individual biomarker levels or their combinations with pre-to-post biologic changes in asthma outcomes in real-life. Methods: This was a registry-based, cohort study using data from 23 countries, which shared data with the International Severe Asthma Registry (May 2017-February 2023). The investigated biomarkers (highest pre-biologic levels) were immunoglobulin E (IgE), blood eosinophil count (BEC) and fractional exhaled nitric oxide (FeNO). Pre- to approximately 12-month post-biologic change for each of three asthma outcome domains (i.e. exacerbation rate, symptom control and lung function), and the association of this change with pre-biologic biomarkers was investigated for individual and combined biomarkers. Results: Overall, 3751 patients initiated biologics and were included in the analysis. No association was found between pre-biologic BEC and pre-to-post biologic change in exacerbation rate for any biologic class. However, higher pre-biologic BEC and FeNO were both associated with greater post-biologic improvement in FEV1 for both anti-IgE and anti-IL5/5R, with a trend for antiI-IL4R alpha. Mean FEV1 improved by 27-178 mL post-anti-IgE as pre-biologic BEC increased (250 to 1000 cells/mu L), and by 43-216 mL and 129-250 mL post-anti-IL5/5R and - anti- IL4R alpha, respectively along the same BEC gradient. Corresponding improvements along a FeNO gradient (25-100 ppb) were 41-274 mL, 69-207 mL and 148-224 mL for anti-IgE, anti-IL5/5R, and anti-IL4R alpha, respectively. Higher baseline BEC was also associated with lower probability of uncontrolled asthma (OR 0.392; p=0.001) post-biologic for anti-IL5/5R. Pre-biologic IgE was a poor predictor of subsequent pre-to-post-biologic change for
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- 2024
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28. The effects of oral corticosteroids on lung function, type-2 biomarkers and patient-reported outcomes in stable asthma: A systematic review and meta-analysis
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Busby, John, Khoo, Esther, Pfeffer, Paul E., Mansur, Adel H., and Heaney, Liam G.
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- 2020
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29. Characterization of Severe Asthma Worldwide: Data From the International Severe Asthma Registry
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Wang, Eileen, Wechsler, Michael E., Tran, Trung N., Heaney, Liam G., Jones, Rupert C., Menzies-Gow, Andrew N., Busby, John, Jackson, David J., Pfeffer, Paul E., Rhee, Chin Kook, Cho, You Sook, Canonica, G. Walter, Heffler, Enrico, Gibson, Peter G., Hew, Mark, Peters, Matthew, Harvey, Erin S., Alacqua, Marianna, Zangrilli, James, Bulathsinhala, Lakmini, Carter, Victoria A., Chaudhry, Isha, Eleangovan, Neva, Hosseini, Naeimeh, Murray, Ruth B., and Price, David B.
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- 2020
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30. Reply to “Exploring the long-term effects of biologic initiation in severe asthma: Insights from the International Severe Asthma Registry”
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Chen, Wenjia, primary, Tran, Trung N., additional, Sadatsafavi, Mohsen, additional, Murray, Ruth B., additional, Boon Wong, Nigel Chong, additional, Ali, Nasloon, additional, Ariti, Con, additional, Bulathsinhala, Lakmini, additional, Garcia Gil, Esther, additional, FitzGerald, J. Mark, additional, Alacqua, Marianna, additional, Al-Ahmad, Mona, additional, Altraja, Alan, additional, Al-Lehebi, Riyad, additional, Bhutani, Mohit, additional, Bjermer, Leif, additional, Bjerrum, Anne-Sofie, additional, Bourdin, Arnaud, additional, von Bülow, Anna, additional, Busby, John, additional, Canonica, Giorgio Walter, additional, Carter, Victoria, additional, Christoff, George C., additional, Cosio, Borja G., additional, Costello, Richard W., additional, Fonseca, João A., additional, Gibson, Peter G., additional, Yoo, Kwang Ha, additional, Heaney, Liam G., additional, Heffler, Enrico, additional, Hew, Mark, additional, Hilberg, Ole, additional, Hoyte, Flavia, additional, Iwanaga, Takashi, additional, Jackson, David J., additional, Jones, Rupert C., additional, Koh, Mariko Siyue, additional, Kuna, Piotr, additional, Larenas-Linnemann, Désirée, additional, Lehmann, Sverre, additional, Lehtimäki, Lauri, additional, Lyu, Juntao, additional, Mahboub, Bassam, additional, Maspero, Jorge, additional, Menzies-Gow, Andrew N., additional, Newell, Anthony, additional, Sirena, Concetta, additional, Papadopoulos, Nikolaos G., additional, Papaioannou, Andriana I., additional, Perez-de-Llano, Luis, additional, Perng (Steve), Diahn-Warng, additional, Peters, Matthew J., additional, Pfeffer, Paul E., additional, Porsbjerg, Celeste M., additional, Popov, Todor A., additional, Rhee, Chin Kook, additional, Salvi, Sundeep, additional, Taillé, Camille, additional, Taube, Christian, additional, Torres-Duque, Carlos A., additional, Ulrik, Charlotte, additional, Ra, Seung Won, additional, Wang, Eileen, additional, Wechsler, Michael E., additional, and Price, David B., additional
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- 2024
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31. Ethnic variation in asthma phenotypic presentation and outcomes: a cross-sectional analysis of the UK Biobank
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Busby, John, primary, McDowell, P Jane, additional, Pfeffer, Paul E, additional, Mansur, Adel Hasan, additional, and Heaney, Liam G, additional
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- 2023
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32. Impact of pre-biologic impairment on meeting domain-specific biologic responder definitions in patients with severe asthma
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Perez-de-Llano, Luis, primary, Scelo, Ghislaine, additional, Canonica, G. Walter, additional, Chen, Wenjia, additional, Henley, William, additional, Larenas-Linnemann, Désirée, additional, Peters, Matthesadatw J, additional, Pfeffer, Paul E., additional, Tran, Trung N., additional, Ulrik, Charlotte Suppli, additional, Popov, Todor A., additional, Sadatsafavi, Mohsen, additional, Hew, Mark, additional, Maspero, Jorge, additional, Gibson, Peter G., additional, Christoff, George C., additional, Fitzgerald, J. Mark, additional, Torres-Duque, Carlos A., additional, Porsbjerg, Celeste M., additional, Papadopoulos, Nikolaos G., additional, Papaioannou, Andriana I., additional, Heffler, Enrico, additional, Iwanaga, Takashi, additional, Al-Ahmad, Mona, additional, Kuna, Piotr, additional, Fonseca, João A, additional, Al-Lehebi, Riyad, additional, Rhee, Chin Kook, additional, Koh, Mariko Siyue, additional, Cosio, Borja G., additional, Perng (Steve), Diahn-Warng, additional, Mahboub, Bassam, additional, Menzies-Gow, Andrew N., additional, Jackson, David J., additional, Busby, John, additional, Heaney, Liam G., additional, Patel, Pujan H, additional, Wang, Eileen, additional, Wechsler, Michael E., additional, Altraja, Alan, additional, Lehtimäki, Lauri, additional, Bourdin, Arnaud, additional, Bjermer, Leif, additional, Bulathsinhala, Lakmini, additional, Carter, Victoria, additional, Murray, Ruth, additional, Beastall, Aaron, additional, Denton, Eve, additional, and Price, David B., additional
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- 2023
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33. Historical reconstruction unveils the risk of mass mortality and ecosystem collapse during pancontinental megadrought
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Godfree, Robert C., Knerr, Nunzio, Godfree, Denise, Busby, John, Robertson, Bruce, and Encinas-Viso, Francisco
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- 2019
34. Preventing unnecessary unplanned hospital admissions and achieving timely discharge; an analysis of geographic variation
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Busby, John
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362.11 - Abstract
Background. Reducing unplanned hospital admissions and achieving timely discharge are key issues for healthcare systems worldwide. Policymakers have focussed on admissions for ambulatory care sensitive conditions (ACSCs) as they are potentially avoidable. Exploring geographic variation could identify variable care pathways. Aims. To investigate the magnitude and causes of geographic variation in unplanned ACSC care. To explore key methodological issues pertinent to small-area variation studies and how this data can inform local decisions. Methods. I conducted a systematic review exploring the magnitude and causes of geographic variation. I estimated geographic variation in ACSC admission rates, length of stay and.readmission rates between PCTs and general practices. I investigated what might be driving these differences. I contrasted geographic variation across patient subgroups. I examined how methodological issues impacted the conclusions of small-area variation studies. I explored how benchmarking is used locally. Results. ACSCs are a large and growing problem. Care processes were highly variable for most, although not all, conditions. Admissions for younger patients, or those with low illness severity, were consistently more variable. Areas with greater bed availability, reduced care continuity and increased A&E proximity had consistently higher admission rates. A range of methodologies were used to quantify geographic variation which can impact conclusions and hinder comparisons. Benchmarking is widely used locally however perceptions of poor data reliability sometimes undermined its utility. Conclusions. There are important differences in ACSC care processes across England. Further work is needed to understand the causes of these differences and should initially focus on the most variable conditions and patient subgroups. Several factors are strongly associated with admission rates; where possible the causal effect of these should be tested using more robust study designs. Improvements in the reliability of routinely collected data, and the methodological rigor of small-area variation studies, is needed to improve their utility.
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- 2015
35. Impact of sex on severe asthma: a cross-sectional retrospective analysis of UK primary and specialist care.
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Loewenthal, Lola, Busby, John, McDowel, Ronald, Brown, Thomas, Burhan, Hassan, Chaudhuri, Rekha, Dennison, Paddy, Dodd, James William, Doe, Simon, Faruqi, Shoaib, Gore, Robin, Idris, Elfatih, Jackson, David Joshua, Patel, Mitesh, Pantin, Thomas, Pavord, Ian, Pfeffer, Paul E., Price, David B., Rupani, Hitasha, and Siddiqui, Salman
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ATOPY ,ASTHMA ,PULMONARY eosinophilia ,SEX factors in disease ,PRIMARY care ,CROSS-sectional method - Published
- 2024
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36. Association Between T2-related Comorbidities and Effectiveness of Biologics in Severe Asthma
- Author
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Wechsler, Michael E, primary, Scelo, Ghislaine, additional, Larenas-Linnemann, Désirée E. S., additional, Torres-Duque, Carlos A., additional, Maspero, Jorge, additional, Tran, Trung N., additional, Murray, Ruth B., additional, Martin, Neil, additional, Menzies-Gow, Andrew N., additional, Hew, Mark, additional, Peters, Matthew J, additional, Gibson, Peter G, additional, Christoff, George C., additional, Popov, Todor A., additional, Côté, Andréanne, additional, Bergeron, Celine, additional, Dorscheid, Delbert, additional, FitzGerald, J Mark, additional, Chapman, Kenneth R, additional, Boulet, Louis Philippe, additional, Bhutani, Mohit, additional, Sadatsafavi, Mohsen, additional, Jiménez-Maldonado, Libardo, additional, Duran-Silva, Mauricio, additional, Rodriguez, Bellanid, additional, Celis-Preciado, Carlos Andres, additional, Cano-Rosales, Diana Jimena, additional, Solarte, Ivan, additional, Fernandez- Sanchez, Maria Jose, additional, Parada-Tovar, Patricia, additional, von Bülow, Anna, additional, Bjerrum, Anne Sofie, additional, Ulrik, Charlotte S, additional, Assing, Karin Dahl, additional, Rasmussen, Linda Makowska, additional, Hansen, Susanne, additional, Altraja, Alan, additional, Bourdin, Arnaud, additional, Taille, Camille, additional, Charriot, Jeremy, additional, Roche, Nicolas, additional, Papaioannou, Andriana I, additional, Kostikas, Konstantinos, additional, Papadopoulos, Nikolaos G., additional, Salvi, Sundeep, additional, Long, Deirdre, additional, Mitchell, Patrick D, additional, Costello, Richard, additional, Sirena, Concetta, additional, Cardini, Cristina, additional, Heffler, Enrico, additional, Puggioni, Francesca, additional, Canonica, Giorgio Walter, additional, Guida, Giuseppe, additional, Iwanaga, Takashi, additional, Al-Ahmad, Mona, additional, García, Ulises, additional, Kuna, Piotr, additional, Fonseca, João A., additional, Al-Lehebi, Riyad, additional, Koh, Mariko S., additional, Rhee, Chin Kook, additional, Cosio, Borja G, additional, Perez de Llano, Luis, additional, Perng, Diahn-Warng, additional, Huang, Erick Wan-Chun, additional, Wang, Hao-Chien, additional, Tsai, Ming-Ju, additional, Mahboub, Bassam, additional, Salameh, Laila Ibraheem Jaber, additional, Jackson, David J., additional, Busby, John, additional, Heaney, Liam G, additional, Pfeffer, Paul E., additional, Goddard, Amanda Grippen, additional, Wang, Eileen, additional, Hoyte, Flavia C. L., additional, Chapman, Nicholas M, additional, Katial, Rohit, additional, Carter, Victoria, additional, Bulathsinhala, Lakmini, additional, Eleangovan, Neva, additional, Ariti, Con, additional, Lyu, Juntao, additional, Porsbjerg, Celeste, additional, and Price, David B., additional
- Published
- 2023
- Full Text
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37. Pharmacoequity in Allergy-Immunology: Disparities in Access to Medications for Allergic Diseases and Proposed Solutions in the US and Globally
- Author
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Maldonado-Puebla, Martin, primary, Akenroye, Ayobami, additional, Busby, John, additional, Cardet, Juan Carlos, additional, and Louisias, Margee, additional
- Published
- 2023
- Full Text
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38. Clinical remission in severe asthma with biologic therapy: an analysis from the UK Severe Asthma Registry
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McDowell, P. Jane, primary, McDowell, Ron, additional, Busby, John, additional, Eastwood, M. Chad, additional, Patel, Pujan H., additional, Jackson, David J., additional, Mansur, Adel, additional, Patel, Mitesh, additional, Burhan, Hassan, additional, Doe, Simon, additional, Chaudhuri, Rekha, additional, Gore, Robin, additional, Dodd, James W., additional, Subramanian, Deepak, additional, Brown, Thomas, additional, and Heaney, Liam G., additional
- Published
- 2023
- Full Text
- View/download PDF
39. Adult Severe Asthma Registries: A Global and Growing Inventory
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Cushen, Breda, primary, Koh, Mariko Siyue, additional, Tran, Trung N, additional, Martin, Neil, additional, Murray, Ruth, additional, Uthaman, Thendral, additional, Goh, Celine Yun Yi, additional, Vella, Rebecca, additional, Eleangovan, Neva, additional, Bulathsinhala, Lakmini, additional, Maspero, Jorge, additional, Peters, Matthew, additional, Schleich, Florence, additional, Pitrez, Paulo, additional, Christoff, George, additional, Sadatsafavi, Mohsen, additional, Torres-Duque, Carlos A, additional, Porsbjerg, Celeste, additional, Altraja, Alan, additional, Lehtimäki, Lauri, additional, Bourdin, Arnaud, additional, Taube, Christian, additional, Papadopoulos, Nikolaos G, additional, Zsuzsanna, Csoma, additional, Björnsdóttir, Unnur, additional, Salvi, Sundeep, additional, Heffler, Enrico, additional, Iwanaga, Takashi, additional, al-Ahmad, Mona, additional, Larenas-Linnemann, Désirée, additional, van Boven, Job FM, additional, Aarli, Bernt Bøgvald, additional, Kuna, Piotr, additional, Loureiro, Cláudia Chaves, additional, Al-lehebi, Riyad, additional, Lee, Jae Ha, additional, Marina, Nuria, additional, Bjermer, Leif, additional, Sheu, Chau-Chyun, additional, Mahboub, Bassam, additional, Busby, John, additional, Menzies-Gow, Andrew, additional, Wang, Eileen, additional, and Price, David, additional
- Published
- 2023
- Full Text
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40. Difficult‐to‐treat asthma patients from ethnic minority groups in central England are at an enhanced risk of house dust mite sensitisation
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Mansur, Adel H., primary, Marsh, Julie, additional, Bahron, Ali, additional, Thomas, Maximillian, additional, Walters, Gareth, additional, Busby, John, additional, Heaney, Liam G., additional, and Krishna, Mamidipudi Thirumala, additional
- Published
- 2023
- Full Text
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41. Clinical remission following biologic initiation in severe asthma: results of the International Severe Asthma Registry (ISAR)
- Author
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Scelo, Ghislaine, primary, Tran, Trung N., additional, Le, Tham T., additional, Faregås, Malin, additional, Martin, Neil, additional, Menzies-Gow, Andrew N., additional, Eileen, Wang, additional, Wechsler, Michael, additional, Canonica, Giorgio Walter, additional, Heffler, Enrico, additional, Heaney, Liam G., additional, Jackson, David J., additional, Pfeffer, Paul E, additional, Busby, John, additional, Porsbjerg, Celeste M., additional, Hew, Mark, additional, Peters, Matthew, additional, Gibson, Peter G., additional, Al-Ahmad, Mona, additional, Bergeron, Celine, additional, Sadatsafavi, Mohsen, additional, Perez-De-Llano, Luis, additional, Cosio, Borja G, additional, Kuna, Piotr, additional, Perng, Diahn-Warng, additional, Iwanaga, Takashi, additional, Torres-Duque, Carlos A., additional, Larenas-Linnemann, Désirée, additional, Mahboub, Bassam, additional, Al-Lehebi, Riyad, additional, Fonseca, João A., additional, Rhee, Chin Kook, additional, Máspero, Jorge, additional, Siyue, Mariko Koh, additional, Christoff, George C, additional, Popov, Todor A., additional, Kwiatek, Justin, additional, Carter, Victoria, additional, Goh, Celine, additional, Bulathsinhala, Lakmini, additional, Beastall, Aaron, additional, and Price, David, additional
- Published
- 2023
- Full Text
- View/download PDF
42. Real-world associations between outcomes and biomarkers in severe asthma patients treated with biologics
- Author
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Townend, John, primary, Tran, Trung N, additional, Martin, Neil, additional, Menzies-Gow, Andrew N., additional, Wang, Eileen, additional, Wechsler, Michael E., additional, Canonica, Giorgio Walter, additional, Heffler, Enrico, additional, Perez-De-Llano, Luis, additional, Cosio, Borja G., additional, Hew, Mark, additional, Peters, Matthew, additional, Gibson, Peter G., additional, Bosnic-Anticevich, Sinthia, additional, Heaney, Liam G., additional, Jackson, David J., additional, Pfeffer, Paul E., additional, Busby, John, additional, Salvi, Sundeep, additional, Christoff, George C., additional, Popov, Todor A., additional, Porsbjerg, Celeste M., additional, Torres-Duque, Carlos A., additional, Al-Lehebi, Riyad, additional, Al-Ahmad, Mona, additional, Perng, Diahn-Warng, additional, Bergeron, Celine, additional, Sadatsafavi, Mohsen, additional, Mahboub, Bassam, additional, Iwanaga, Takashi, additional, Maspero, Jorge, additional, Kuna, Piotr, additional, Chin, Kook Rhee, additional, Larenas-Linnemann, Désirée, additional, Papadopoulos, Nikolaos G., additional, Papaioannou, Andriana I., additional, Fonseca, João A., additional, Siyue Koh, Mariko, additional, Costello, Richard W., additional, and Price, David, additional
- Published
- 2023
- Full Text
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43. Additional effects of oral prednisolone following mepolizumab on the nasal transcriptome
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Howell, Imran, primary, Yang, Freda, additional, Cane, Jennifer, additional, Busby, John, additional, Heaney, Liam G, additional, Howarth, Peter, additional, Pavord, Ian D, additional, Brightling, Chris E, additional, Hinks, Timothy Sc, additional, and Chaudhuri, Rekha, additional
- Published
- 2023
- Full Text
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44. Longitudinal assessment of glucocorticoid toxicity in biologics treated severe asthma
- Author
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McDowell, Pamela Jane, primary, Busby, John, additional, Stone, John, additional, Honeyford, Kirsty, additional, Dunn, Louise, additional, Butler, Claire, additional, and Heaney, Liam, additional
- Published
- 2023
- Full Text
- View/download PDF
45. Real world biologic treatment response in severe asthma: an analysis of the International Severe Asthma Registry (ISAR)
- Author
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Le, Tham T., primary, Scelo, Ghislaine, additional, Tran, Trung N.., additional, Faregås, Malin, additional, Martin, Neil, additional, Menzies-Gow, Andrew N., additional, Eileen, Wang, additional, Wechsler, Michael, additional, Canonica, Giorgio Walter, additional, Heffler, Enrico, additional, Heaney, Liam G., additional, Jackson, David J., additional, Pfeffer, Paul E., additional, Busby, John, additional, Porsbjerg, Celeste M., additional, Hew, Mark, additional, Peters, Matthew, additional, Gibson, Peter G., additional, Al-Ahmad, Mona, additional, Bergeron, Celine, additional, Sadatsafavi, Mohsen, additional, Perez-De-Llano, Luis, additional, Cosio, Borja G., additional, Kuna, Piotr, additional, Perng, Diahn-Warng, additional, Iwanaga, Takashi, additional, Torres-Duque, Carlos A., additional, Larenas-Linnemann, Désirée, additional, Mahboub, Bassam, additional, Papadopoulos, Nikolaos G., additional, Al-Lehebi, Riyad, additional, Fonseca, João A., additional, Rhee, Chin Kook, additional, Máspero, Jorge, additional, Siyue, Mariko Koh, additional, Christoff, George C., additional, Popov, Todor A., additional, Kwiatek, Justin, additional, Carter, Victoria, additional, Goh, Celine, additional, Bulathsinhala, Lakmini, additional, Beastall, Aaron, additional, and Price, David, additional
- Published
- 2023
- Full Text
- View/download PDF
46. Urinary eicosanoids - novel biomarkers in T2-low severe asthma
- Author
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Eastwood, Matthew, primary, Busby, John, additional, Kolmert, Johan, additional, Wheelock, Craig, additional, Dahlén, Sven-Erik, additional, Mcdowell, Pamela-Jane, additional, Jackson, David, additional, Djukanovic, Ratko, additional, Matthews, John, additional, Arron, Joseph, additional, Bradding, Peter, additional, Brightling, Chris, additional, Chaudhuri, Rekha, additional, Choy, David, additional, Cowan, Douglas, additional, Fowler, Stephen, additional, Hanratty, Catherine, additional, Hardman, Timothy, additional, Harrison, Timothy, additional, Holweg, Cecile, additional, Howarth, Peter, additional, Lordan, James, additional, Mansur, Adel, additional, Menzies-Gow, Andrew, additional, Pavord, Ian, additional, Robinson, Douglas, additional, Walker, Samantha, additional, Woodcock, Ashley, additional, and Heaney, Liam, additional
- Published
- 2023
- Full Text
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47. Characteristics associated with clinical remission in patients with severe asthma who initiate biologics
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Pérez De Llano, Luis, primary, Scelo, Ghislaine, additional, Tran, Trung N, additional, T. Le, Tham, additional, Martin, Neil, additional, Fagerås, Malin, additional, Menzies-Gow, Andrew N., additional, Wang, Eileen, additional, E. Wechsler, Michael, additional, Canonica, Giorgio Walter, additional, Heffler, Enrico, additional, Heaney, Liam G., additional, Jackson, David J., additional, Pfeffer, Paul E., additional, Busby, John, additional, Porsbjerg, Celeste M., additional, Hew, Mark, additional, Peters, Matthew, additional, Gibson, Peter G., additional, Al-Ahmad, Mona, additional, Bergeron, Celine, additional, Sadatsafavi, Mohsen, additional, Cosio, Borja G., additional, Kuna, Piotr, additional, Perng, Diahn-Warng, additional, Iwanaga, Takashi, additional, Torres-Duque, Carlos A., additional, Larenas-Linnemann, Désirée, additional, Mahboub, Bassam, additional, Papadopoulos, Nikolaos G., additional, Al-Lehebi, Riyad, additional, Fonseca, João A., additional, Kook Rhee, Chin, additional, Máspero, Jorge, additional, Koh, Mariko Siyue, additional, Christoff, George C., additional, Popov, Todor A., additional, Kwiatek, Justin, additional, Carter, Victoria, additional, Goh, Celine, additional, Bulathsinhala, Lakmini, additional, Beastall, Aaron, additional, and Price, David, additional
- Published
- 2023
- Full Text
- View/download PDF
48. Unsupervised home spirometryversussupervised clinic spirometry for respiratory disease: a systematic methodology review and meta-analysis
- Author
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Anand, Rohan, primary, McLeese, Rebecca, additional, Busby, John, additional, Stewart, Jonathan, additional, Clarke, Mike, additional, Man, William D-C., additional, and Bradley, Judy, additional
- Published
- 2023
- Full Text
- View/download PDF
49. Postdiagnostic Calcium Channel Blocker Use and Breast Cancer Mortality : A Population-based Cohort Study
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Busby, John, Mills, Ken, Zhang, Shu-Dong, Liberante, Fabio Giuseppe, and Cardwell, Chris R.
- Published
- 2018
50. Model for Identifying Individuals at Risk for Esophageal Adenocarcinoma
- Author
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Kunzmann, Andrew T., Thrift, Aaron P., Cardwell, Chris R., Lagergren, Jesper, Xie, Shaohua, Johnston, Brian T., Anderson, Lesley A., Busby, John, McMenamin, Úna C., Spence, Andrew D., and Coleman, Helen G.
- Published
- 2018
- Full Text
- View/download PDF
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