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Patients with drug-resistant tuberculosis (DR-TB) have received community-based care in Eswatini since 2009. Trained and compensated community treatment supporters (CTSs) provide directly observed therapy (DOT), injectables and psychological support. We examined the acceptability of this model of care among DR-TB patients, including the perspective of family members of DR-TB patients and their CTSs in relation to the patient's experience of care and quality of life. This qualitative research was conducted in rural Eswatini in February 2018. DR-TB patients, CTSs and family members participated in in-depth interviews, paired interviews, focus group discussions and PhotoVoice. Data were thematically analysed and coded, and themes were extracted. Methodological triangulation enhanced the interpretation. All patients and CTSs and most family members considered community-based DR-TB care to be supportive. Positive aspects were emotional support, trust and dedicated individual care, including enabling practical, financial and social factors. Concerns were related to social and economic problems within the family and fears about infection risks for the family and the CTSs. Community-based DR-TB care was acceptable to patients, family members and CTSs. To reduce family members' fears of TB infection, information and sensitisation within the family and constant follow-up appear crucial. [ABSTRACT FROM AUTHOR]

Purpose: The clinical evaluation of one-piece zirconia dental implants with different diameters to determine survival rate and type of implant failure. Materials and Methods: Information concerning implant surgery (number, diameter, length, and position of inserted implants; patient age, sex, risk factors, and bone quality) was extracted from the clinical records. All treated patients were then recalled for a follow-up examination to check the current clinical parameters concerning soft tissue, implants, and prosthetic reconstructions. Results: A total of 79 patients received 170 implants (diameter-reduced 3.25 mm: n = 59; diameter 4.0 mm: n = 82; diameter 5.0 mm: n = 29). The clinical examination showed no signs of gingival inflammation. Prosthetic information was available for 119 implants restored with single crowns (87 implants), fixed partial dentures (25 implants), and removable hybrid dentures (7 implants). Overall, 30 implants were lost due to lack of osseointegration (n = 17) or fracture (n = 13). The diameter-reduced implants showed the lowest survival rate (59.5%) compared to the implants with a diameter of 4.0 mm (90.6%) and 5.0 mm (73.9%). The survival rate for diameters of 3.25 mm was significantly lower than that for diameters of 4.0 mm. The estimated cumulative survival rate up to 3 years demonstrated a survival probability of 82.4% for all types of implant diameters and failure. Conclusions: Based on these results, diameter-reduced zirconia dental implants cannot be recommended for clinical use. The overall survival rate of 82.4% is not acceptable in comparison to the well-established survival rate of titanium implants [ABSTRACT FROM AUTHOR]

Purpose: The aim of this clinical retrospective study was to evaluate the clinical performance and longevity of glass-ceramic onlays and inlays in stress-bearing posterior teeth. Materials and Methods: Five hundred forty-seven posterior teeth in the maxillae and mandibles of 120 patients (46 males, 74 females) were restored with 213 onlays, 38 single-surface inlays, 141 two-surface inlays, and 155 three-surface inlays between 1987 and 2009 at Innsbruck Medical University, Innsbruck, Austria, by two experienced dentists. The restoration sample included 9 (1.6%) nonvital teeth and 40 (33%) patients diagnosed with bruxism. The study population was examined clinically during regularly scheduled maintenance appointments. The risk of failure was determined using Kaplan-Meier survival analyses. Results: The mean observation periods for onlays and all inlays were 80 ± 34 months and 111 ± 63 months, respectively. Twenty-seven failures were recorded. The estimated survival rates for onlays and all inlays after 5, 10, and 12 years were 98.9% and 98.9%, 92.4% and 96.8%, and 92.4% and 89.6%, respectively. Nonvital teeth showed a significantly higher risk of failure (P < .001). There was no greater risk of failure associated with existing parafunction (bruxism) (P = .408). Restorations on premolars survived longer in the first 15 years than restorations on molars, but no statistical significance was found (P = .913). Conclusion: Glass-ceramic onlays and inlays were demonstrated to be successful in posterior teeth; however, at this time, their efficacy is inferior to that of cast gold restorations. [ABSTRACT FROM AUTHOR]

Purpose: The aim of this clinical retrospective study was to evaluate the clinical quality, success rate, and estimated survival rate of anterior veneers made of silicate glassceramic in a long-term analysis of up to 20 years. Materials and Methods: Anterior teeth in the maxillae and mandibles of 84 patients (38 men, 46 women) were restored with 318 porcelain veneer restorations between 1987 and 2009 at the Medical University Innsbruck, Innsbruck, Austria. Clinical examination was performed during patients' regularly scheduled maintenance appointments. Esthetic match, porcelain surface, marginal discoloration, and integrity were evaluated following modified California Dental Association/Ryge criteria. Veneer failures and reasons for failure were recorded. The study population included 42 (50.0%) patients diagnosed with bruxism and 23 (27.38%) smokers. The success rate was determined using Kaplan-Meier survival analysis. Results: The mean observation time was 118 ± 63 months. Twenty-nine failures (absolute:82.76%, relative: 17.24%) were recorded. The main reason for failure was fracture of the ceramic (44.83%). The estimated survival rate was 94.4% after 5 years, 93.5% at 10 years, and 82.93% at 20 years. Nonvital teeth showed a significantly higher failure risk (P = .0012). There was a 7.7-times greater risk of failure associated with existing parafunction (bruxism, P = .0004). Marginal discoloration was significantly greater in smokers (P = .01). Conclusion: Porcelain laminate veneers offer a predictable and successful restoration with an estimated survival probability of 93.5% over 10 years. Significantly increased failure rates were associated with bruxism and nonvital teeth, and marginal discoloration was worse in patients who smoked. [ABSTRACT FROM AUTHOR]