Search

Your search keyword '"Burkhardt, Jan-Karl"' showing total 1,175 results
Start Over Author "Burkhardt, Jan-Karl"
1,175 results on '"Burkhardt, Jan-Karl"'

2. Complex intracranial aneurysms: a DELPHI study to define associated characteristics

Author

Diana, Francesco, Romoli, Michele, Raz, Eytan, Agid, Ronit, Albuquerque, Felipe C., Arthur, Adam S., Beck, Jürgen, Berge, Jerome, Boogaarts, Hieronymus D., Burkhardt, Jan-Karl, Cenzato, Marco, Chapot, René, Charbel, Fady T., Desal, Hubert, Esposito, Giuseppe, Fifi, Johanna T., Florian, Stefan, Gruber, Andreas, Hassan, Ameer E., Jabbour, Pascal, Jadhav, Ashutosh P., Korja, Miikka, Krings, Timo, Lanzino, Giuseppe, Meling, Torstein R., Morcos, Jaques, Mosimann, Pascal J., Nossek, Erez, Pereira, Vitor Mendes, Raabe, Andreas, Regli, Luca, Rohde, Veit, Siddiqui, Adnan H., Tanikawa, Rokuya, Tjoumakaris, Stavropoula I., Tomasello, Alejandro, Vajkoczy, Peter, Valvassori, Luca, Velinov, Nikolay, Walsh, Daniel, Woo, Henry, Xu, Bin, Yoshimura, Shinichi, van Zwam, Wim H., and Peschillo, Simone

Published
2024
Full Text
View/download PDF

4. Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Author

Dmytriw, Adam A., Salim, Hamza, Musmar, Basel, Aslan, Assala, Cancelliere, Nicole M., McLellan, Rachel M., Algin, Oktay, Ghozy, Sherief, Dibas, Mahmoud, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, Naamani, Kareem El, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad U., Catapano, Joshua, Waqas, Muhammad, Tutino, Vincent M., Ibrahim, Mohamed K., Mohammed, Marwa A., Imamoglu, Cetin, Bayrak, Ahmet, Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer E., Ogilvie, Mark, Sporns, Peter, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie T., Psychogios, Marios, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan-Karl, Huynh, Thien, Martinez-Gutierrez, Juan Carlos, Essibayi, Muhammed Amir, Sheth, Sunil A., Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph J., Asadi, Hamed, Siddiqui, Adnan, Brook, Allan L., Altschul, David, Ducruet, Andrew F., Albuquerque, Felipe C., Regenhardt, Robert W., Stapleton, Christopher J., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Tjoumakaris, Stavropoula I., Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo H., Jabbour, Pascal M., Pereira, Vitor Mendes, Patel, Aman B., and Adeeb, Nimer

Published
2024
Full Text
View/download PDF

12. Clinical outcomes after revascularization for pediatric moyamoya disease and syndrome: A single-center series.

Author

Morshed, Ramin A, Abla, Adib A, Murph, Daniel, Dao, Jasmin M, Winkler, Ethan A, Burkhardt, Jan-Karl, Colao, Kathleen, Hetts, Steven W, Fullerton, Heather J, Lawton, Michael T, Gupta, Nalin, and Fox, Christine K

Subjects
Humans, Moyamoya Disease, Syndrome, Postoperative Complications, Treatment Outcome, Cerebral Revascularization, Retrospective Studies, Cohort Studies, Adolescent, Child, Child, Preschool, Infant, Female, Male, Stroke, Direct and indirect revascularization technique, Moyamoya disease, STA-MCA bypass, Vascular disorders, Pediatric, Clinical Research, Brain Disorders, Neurosciences, Patient Safety, Clinical Sciences, Neurology & Neurosurgery
Abstract

Moyamoya is a progressive cerebrovascular arteriopathy that affects children of any age. The goal of this study was to determine imaging and clinical outcomes as well as complication rates in a pediatric cohort undergoing either a combined direct/indirect or indirect-only revascularization approach. Patients with moyamoya disease or syndrome ≤ 18 years of age at the time of initial surgery were identified, and clinical data were collected retrospectively. Over a 12-year period, 26 patients underwent revascularization procedures on 49 hemispheres with a median follow-up of 2.6 years from surgery. Median age at surgery was 7.3 years (range 1.4-18.0 years). Thirty-three hemispheres (67.3%) underwent combined revascularization with a direct bypass and encephalomyosynangiosis, and sixteen hemispheres (32.7%) underwent indirect-only revascularization. The rate of 30-day perioperative complication was 10.2%, and the rate of postoperative clinical stroke by end of follow-up was 10.2% by hemisphere. There was a 5.7% rate of intraoperative bypass failure requiring conversion to an indirect revascularization approach. On follow-up imaging, 96.9% of direct bypasses remained patent. On multivariate analysis, higher preoperative Pediatric Stroke Outcome Measure (PSOM) scores were associated with lower rates of good clinical outcome on follow-up (unit OR 0.03; p = 0.03). Patients with age

Published
2020

13. Bringing high-grade arteriovenous malformations under control: clinical outcomes following multimodality treatment in children.

Author

Winkler, Ethan A, Lu, Alex, Morshed, Ramin A, Yue, John K, Rutledge, W Caleb, Burkhardt, Jan-Karl, Patel, Arati B, Ammanuel, Simon G, Braunstein, Steve, Fox, Christine K, Fullerton, Heather J, Kim, Helen, Cooke, Daniel, Hetts, Steven W, Lawton, Michael T, Abla, Adib A, and Gupta, Nalin

Subjects
ARUBA = A Randomized Trial of Unruptured Brain AVMs, AVM = arteriovenous malformation, DSA = digital subtraction angiography, NBCA = N-butyl cyanoacrylate, SAIVM = Scottish Audit of Intracranial Vascular Malformations, SM = Spetzler-Martin, SRS = stereotactic radiosurgery, Supp-SM = supplemented SM, arteriovenous malformation, embolization, mRS = modified Rankin Scale, pediatric, radiosurgery, surgery, treatment, vascular disorders, Neurology & Neurosurgery, Paediatrics and Reproductive Medicine
Abstract

OBJECTIVE:Brain arteriovenous malformations (AVMs) consist of dysplastic blood vessels with direct arteriovenous shunts that can hemorrhage spontaneously. In children, a higher lifetime hemorrhage risk must be balanced with treatment-related morbidity. The authors describe a collaborative, multimodal strategy resulting in effective and safe treatment of pediatric AVMs. METHODS:A retrospective analysis of a prospectively maintained database was performed in children with treated and nontreated pediatric AVMs at the University of California, San Francisco, from 1998 to 2017. Inclusion criteria were age ≤ 18 years at time of diagnosis and an AVM confirmed by a catheter angiogram. RESULTS:The authors evaluated 189 pediatric patients with AVMs over the study period, including 119 ruptured (63%) and 70 unruptured (37%) AVMs. The mean age at diagnosis was 11.6 ± 4.3 years. With respect to Spetzler-Martin (SM) grade, there were 38 (20.1%) grade I, 40 (21.2%) grade II, 62 (32.8%) grade III, 40 (21.2%) grade IV, and 9 (4.8%) grade V lesions. Six patients were managed conservatively, and 183 patients underwent treatment, including 120 resections, 82 stereotactic radiosurgery (SRS), and 37 endovascular embolizations. Forty-four of 49 (89.8%) high-grade AVMs (SM grade IV or V) were treated. Multiple treatment modalities were used in 29.5% of low-grade and 27.3% of high-grade AVMs. Complete angiographic obliteration was obtained in 73.4% of low-grade lesions (SM grade I-III) and in 45.2% of high-grade lesions. A periprocedural stroke occurred in a single patient (0.5%), and there was 1 treatment-related death. The mean clinical follow-up for the cohort was 4.1 ± 4.6 years, and 96.6% and 84.3% of patients neurologically improved or remained unchanged in the ruptured and unruptured AVM groups following treatment, respectively. There were 16 bleeding events following initiation of AVM treatment (annual rate: 0.02 events per person-year). CONCLUSIONS:Coordinated multidisciplinary evaluation and individualized planning can result in safe and effective treatment of children with AVMs. In particular, it is possible to treat the majority of high-grade AVMs with an acceptable safety profile. Judicious use of multimodality therapy should be limited to appropriately selected patients after thorough team-based discussions to avoid additive morbidity. Future multicenter studies are required to better design predictive models to aid with patient selection for multimodal pediatric care, especially with high-grade AVMs.

Published
2020

14. Moyamoya Disease

Author

Kvint, Svetlana, Burkhardt, Jan-Karl, Mascitelli, Justin R., editor, and Binning, Mandy J., editor

Published
2022
Full Text
View/download PDF

16. Haptoglobin Treatment for Aneurysmal Subarachnoid Hemorrhage: Review and Expert Consensus on Clinical Translation

Author

Galea, Ian, Bandyopadhyay, Soham, Bulters, Diederik, Humar, Rok, Hugelshofer, Michael, Schaer, Dominik J., Abdulazim, Amr, Alalade, Andrew F., Alexander, Sheila A., Amaro, Sergi, Amin-Hanjani, Sepideh, Andersen, Christopher R., Anderson, Craig, Anstey, Matthew H., Balla, József, Bankole, Nourou Dine Adeniran, Bellapart, Judith, Bhagat, Hemant, Blackburn, Spiros L., Brechmann, Markus, Buehler, Paul W., Burkhardt, Jan-Karl, Chen, Yujie, Cohen, Jeremy, Cooper, P. David, Coulthard, Liam G., Cuadrado-Godia, Elisa, Dalton, Joan, Delaney, Anthony, Doré, Sylvain, Downer, Jonathan, Dye, Justin, Fernandez-Perez, Isabel, Flower, Oliver, Fülesdi, Béla, Gaastra, Ben, Gaberel, Thomas, Galea, James, Gankpe, Gbetoho Fortuné, Garland, Patrick, Gentinetta, Thomas, Gram, Magnus, Graversen, Jonas Heilskov, Grover, Patrick J., Guisado-Alonso, Daniel, Hasan, David, Helmy, Adel, Höhne, Julius, Charlotte Hostettler, Isabel, Hrishi, Ajay Prasad, Iihara, Koji, Irwin, David C., Jangra, Kiran, Jiménez-O’Shanahan, Aruma, Keep, Richard F., Koch, Matthew, Korja, Miikka, Kumar, Munish, Llull, Laura, Loan, James JM, Lopez-Gonzalez, Miguel Ángel, Loch Macdonald, R., Mahajan, Shalvi, Martí-Fàbregas, Joan, Medina-Suárez, Jose, Moestrup, Soren, More, John, Morgan, Eghosa, Muthuchellappan, Radhakrishnan, Nyquist, Paul, Sosa Pérez, Coralia, Pillai, Promod, Plesnila, Nikolaus, Javier Provencio, Jose, Raith, Eamon, Ramos-Pachón, Anna, Raymond, Scott B., Regli, Luca, Ruigrok, Ynte Marije, Saharan, Poonam, Samaniego, Edgar A., Schubert, Gerrit Alexander, Seppelt, Ian, Sriganesh, Kamath, Suarez, Jose I., Taylor, Jonathon, Terpolilli, Nicole A., Testai, Fernando D., Tolosano, Emanuela, Toma, Ahmed K., On Tsang, Anderson Chun, Udy, Andrew A., Vallelian, Florence, Vargas-Caballero, Mariana, Vercellotti, Gregory M, Vergouwen, Mervyn D.I., Waak, Michaela, Warming, Hannah, Whitfield, Peter C., Kwok-chu Wong, George, Wright, Jason, and Zuercher, Adrian W.

Published
2023
Full Text
View/download PDF

17. Impact of Race on Outcomes in the Endovascular and Microsurgical Treatment in Patients With Intracranial Aneurysms

Author

Matsukawa, Hidetoshi, primary, Uchida, Kazutaka, additional, Sowlat, Mohammad-Mahdi, additional, Elawady, Sameh Samir, additional, Cunningham, Conor, additional, Alawieh, Ali, additional, Al Kasab, Sami, additional, Jabbour, Pascal, additional, Mascitelli, Justin, additional, Levitt, Michael R., additional, Cuellar, Hugo, additional, Brinjikji, Waleed, additional, Samaniego, Edgar, additional, Burkhardt, Jan-Karl, additional, Kan, Peter, additional, Fox, W. Christopher, additional, Moss, Mark, additional, Ezzeldin, Mohamad, additional, Grandhi, Ramesh, additional, Altschul, David J., additional, Spiotta, Alejandro M, additional, and Yoshimura, Shinichi, additional

Published
2024
Full Text
View/download PDF

18. Multicenter US clinical experience with the Scepter Mini balloon catheter

Author

Salem, Mohamed M., primary, Kelmer, Paz, additional, Sioutas, Georgios S., additional, Ostmeier, Sophie, additional, Hoang, Alex, additional, Cortez, Gustavo, additional, El Naamani, Kareem, additional, Abbas, Rawad, additional, Hanel, Ricardo, additional, Tanweer, Omar, additional, Srinivasan, Visish M., additional, Jabbour, Pascal, additional, Kan, Peter, additional, Jankowitz, Brian T., additional, Heit, Jeremy J., additional, and Burkhardt, Jan-Karl, additional

Published
2024
Full Text
View/download PDF

19. The Influence of Coagulopathy on Radiographic and Clinical Outcomes in Patients Undergoing Middle Meningeal Artery Embolization as Standalone Treatment for Non-acute Subdural Hematomas

Author

Salah, Walid K., primary, Findlay, Matthew C., additional, Baker, Cordell M., additional, Scoville, Jonathan P., additional, Bounajem, Michael T., additional, Ogilvy, Christopher S., additional, Moore, Justin M., additional, Riina, Howard A., additional, Levy, Elad I., additional, Siddiqui, Adnan H., additional, Spiotta, Alejandro M., additional, Cawley, C. Michael, additional, Khalessi, Alexander A., additional, Tanweer, Omar, additional, Hanel, Ricardo, additional, Gross, Bradley A., additional, Kuybu, Okkes, additional, Howard, Brian M., additional, Hoang, Alex N., additional, Baig, Ammad A., additional, Khorasanizadeh, MirHojjat, additional, Mendez Ruiz, Aldo A., additional, Cortez, Gustavo, additional, Davies, Jason M., additional, Lang, Michael J., additional, Thomas, Ajith J., additional, Tonetti, Daniel A., additional, Khalife, Jane, additional, Sioutas, Georgios S., additional, Carroll, Kate, additional, Abecassis, Zachary A., additional, Jankowitz, Brian T., additional, Ruiz Rodriguez, Juan, additional, Levitt, Michael R., additional, Kan, Peter T., additional, Burkhardt, Jan-Karl, additional, Srinivasan, Visish, additional, Salem, Mohamed M., additional, and Grandhi, Ramesh, additional

Published
2024
Full Text
View/download PDF

20. First United States multicenter experience with the new-generation FRED X surface-modified flow diversion stent: feasibility, safety, and short-term efficacy

Author

Abbas, Rawad, primary, Lan, Matthews, additional, Naamani, Kareem El, additional, Atallah, Elias, additional, Salem, Mohamed, additional, Burkhardt, Jan-Karl, additional, Kühn, Anna Luisa, additional, Puri, Ajit, additional, Monteiro, Andre, additional, Levy, Elad I., additional, Herial, Nabeel A., additional, Gooch, M. Reid, additional, Jabbour, Jeffrey, additional, Rosenwasser, Robert, additional, and Tjoumakaris, Stavropoula I., additional

Published
2024
Full Text
View/download PDF

23. Reductions in brain pericytes are associated with arteriovenous malformation vascular instability.

Author

Winkler, Ethan A, Birk, Harjus, Burkhardt, Jan-Karl, Chen, Xiaolin, Yue, John K, Guo, Diana, Rutledge, W Caleb, Lasker, George F, Partow, Carlene, Tihan, Tarik, Chang, Edward F, Su, Hua, Kim, Helen, Walcott, Brian P, and Lawton, Michael T

Subjects
Blood-Brain Barrier, Pericytes, Brain, Endothelial Cells, Humans, Intracranial Arteriovenous Malformations, Vascular Diseases, Receptor, Platelet-Derived Growth Factor beta, Adolescent, Adult, Middle Aged, Child, Female, Male, Young Adult, BBB = blood-brain barrier, CD13 = aminopeptidase N, CD31 = platelet endothelial adhesion molecule 1, GFAP = glial fibrillary acidic protein, MTT = mean transit time, NVLC = nonvascular lesion control, PDGFRβ = platelet-derived growth factor receptor–beta, ROI = region of interest, arteriovenous malformations, bAVM = brain arteriovenous malformation, blood-brain barrier, intracerebral hemorrhage, microhemorrhage, pericytes, stroke, vascular disorders, Neurosciences, Aetiology, 2.1 Biological and endogenous factors, Cardiovascular, Clinical Sciences, Neurology & Neurosurgery
Abstract

OBJECTIVEBrain arteriovenous malformations (bAVMs) are rupture-prone tangles of blood vessels with direct shunting of blood flow between arterial and venous circulations. The molecular and/or cellular mechanisms contributing to bAVM pathogenesis and/or destabilization in sporadic lesions have remained elusive. Initial insights into AVM formation have been gained through models of genetic AVM syndromes. And while many studies have focused on endothelial cells, the contributions of other vascular cell types have yet to be systematically studied. Pericytes are multifunctional mural cells that regulate brain angiogenesis, blood-brain barrier integrity, and vascular stability. Here, the authors analyze the abundance of brain pericytes and their association with vascular changes in sporadic human AVMs.METHODSTissues from bAVMs and from temporal lobe specimens from patients with medically intractable epilepsy (nonvascular lesion controls [NVLCs]) were resected. Immunofluorescent staining with confocal microscopy was performed to quantify pericytes (platelet-derived growth factor receptor-beta [PDGFRβ] and aminopeptidase N [CD13]) and extravascular hemoglobin. Iron-positive hemosiderin deposits were quantified with Prussian blue staining. Syngo iFlow post-image processing was used to measure nidal blood flow on preintervention angiograms.RESULTSQuantitative immunofluorescent analysis demonstrated a 68% reduction in the vascular pericyte number in bAVMs compared with the number in NVLCs (p < 0.01). Additional analysis demonstrated 52% and 50% reductions in the vascular surface area covered by CD13- and PDGFRβ-positive pericyte cell processes, respectively, in bAVMs (p < 0.01). Reductions in pericyte coverage were statistically significantly greater in bAVMs with prior rupture (p < 0.05). Unruptured bAVMs had increased microhemorrhage, as evidenced by a 15.5-fold increase in extravascular hemoglobin compared with levels in NVLCs (p < 0.01). Within unruptured bAVM specimens, extravascular hemoglobin correlated negatively with pericyte coverage (CD13: r = -0.93, p < 0.01; PDGFRβ: r = -0.87, p < 0.01). A similar negative correlation was observed with pericyte coverage and Prussian blue-positive hemosiderin deposits (CD13: r = -0.90, p < 0.01; PDGFRβ: r = -0.86, p < 0.01). Pericyte coverage positively correlated with the mean transit time of blood flow or the time that circulating blood spends within the bAVM nidus (CD13: r = 0.60, p < 0.05; PDGFRβ: r = 0.63, p < 0.05). A greater reduction in pericyte coverage is therefore associated with a reduced mean transit time or faster rate of blood flow through the bAVM nidus. No correlations were observed with time to peak flow within feeding arteries or draining veins.CONCLUSIONSBrain pericyte number and coverage are reduced in sporadic bAVMs and are lowest in cases with prior rupture. In unruptured bAVMs, pericyte reductions correlate with the severity of microhemorrhage. A loss of pericytes also correlates with a faster rate of blood flow through the bAVM nidus. This suggests that pericytes are associated with and may contribute to vascular fragility and hemodynamic changes in bAVMs. Future studies in animal models are needed to better characterize the role of pericytes in AVM pathogenesis.

Published
2018

24. Superficial temporal artery-to-middle cerebral artery bypass in combination with indirect revascularization in moyamoya patients ≤ 3 years of age.

Author

Bot, Gyang Markus, Burkhardt, Jan-Karl, Gupta, Nalin, and Lawton, Michael T

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Patient Safety, Neurosciences, Pediatric, Cardiovascular, Anastomosis, Surgical, Cerebral Revascularization, Child, Preschool, Feasibility Studies, Female, Humans, Infant, Male, Middle Cerebral Artery, Moyamoya Disease, Postoperative Complications, Retrospective Studies, Temporal Arteries, moyamoya disease, direct and indirect revascularization technique, STA-MCA bypass, long-term outcome, vascular disorders, EDAS = encephaloduroarteriosynangiosis, EMS = encephalomyosynangiosis, MCA = middle cerebral artery, MMD = moyamoya disease, STA = superficial temporal artery, TIA = transient ischemic attack, mRS = modified Rankin Scale, Paediatrics and Reproductive Medicine, Neurology & Neurosurgery, Paediatrics
Abstract

OBJECTIVERevascularization is indicated in the management of moyamoya disease (MMD), with options that include direct and indirect techniques. Indirect bypass is popular in young children because the diminutive caliber of donors and recipients makes direct bypass difficult. The authors reviewed a series of patients treated with direct superficial temporal artery (STA)–to–middle cerebral artery (MCA) bypass in combination with encephalomyosynangiosis (EMS) in children 3 years or younger to demonstrate feasibility and safety.METHODSA retrospective review of all surgeries for MMD over a 19-year period identified 11 procedures in 6 patients. Surgical results, angiographic outcomes, and clinical outcomes were analyzed.RESULTSPatients had a mean age of 22.4 months. The symptomatic hemisphere was revascularized first, and the contralateral hemisphere was revascularized on average 2.8 months later in 5 patients. All direct bypasses were patent postoperatively and remained patent at late follow-up (mean 4.1 years), with both STA and MCA diameters increasing significantly (n = 5, p < 0.03). At last follow-up (mean follow-up duration, 5.0 years), favorable outcomes (modified Rankin Scale scores 0–2) were observed in 5 of the 6 patients (83%), with 1 dependent patient remaining unchanged postoperatively.CONCLUSIONSDirect STA-MCA bypass in combination with EMS for MMD is feasible and safe in patients 3 years or younger, based on favorable clinical and radiological outcomes in this patient cohort. Direct bypass should be considered when immediate revascularization is needed, without the biological delay associated with indirect bypass.ABBREVIATIONS EDAS = encephaloduroarteriosynangiosis; EMS = encephalomyosynangiosis; MCA = middle cerebral artery; MMD = moyamoya disease; mRS = modified Rankin Scale; STA = superficial temporal artery; TIA = transient ischemic attack.

Published
2018

25. Microsurgical resection of brain arteriovenous malformations in the elderly: outcomes analysis and risk stratification.

Author

Burkhardt, Jan-Karl, Lasker, George F, Winkler, Ethan A, Kim, Helen, and Lawton, Michael T

Subjects
Patient Safety, Neurosciences, Clinical Research, Aging, Aged, Aged, 80 and over, Brain, Female, Humans, Intracranial Arteriovenous Malformations, Male, Microsurgery, Middle Aged, Neurosurgical Procedures, Retrospective Studies, Risk Assessment, Treatment Outcome, arteriovenous malformation, microsurgical resection, elderly, Spetzler-Martin grading system, Lawton-Young grading system, supplemented Spetzler-Martin grading, vascular disorders, AVM = arteriovenous malformation, LFU = last follow-up, SM = Spetzler-Martin, mRS = modified Rankin Scale, Clinical Sciences, Neurology & Neurosurgery
Abstract

As the population ages, the question of how to manage brain arteriovenous malformations in the elderly becomes increasingly relevant. Is resection a reasonable option for these patients? In this study, the authors examined the outcomes of surgical patients 60 years or older and found that favorable outcomes were achieved with careful patient selection. Preoperative grading scales were more predictive of outcomes in patients older than 65 years than in those 60-65 years of age.

Published
2018

29. The natural history of aneurysms incompletely occluded by placement of a flow diverter: a multiinstitutional study.

Author

Theiss, Peter, Ali, Ahmed Essam, McGuire, Laura Stone, Lanzino, Giuseppe, Ghozy, Sherief, Brinjikji, Waleed, El Naamani, Kareem, Amllay, Abdelaziz, Tjoumakaris, Stavropoula I., Jabbour, Pascal, Salem, Mohamed M., Burkhardt, Jan-Karl, Jankowitz, Brian T., Abla, Adib, Tonetti, Daniel A., Kan, Peter T., Robledo, Ariadna, and Alaraj, Ali

Published
2024
Full Text
View/download PDF

30. Focused update to guidelines for endovascular therapy for emergent large vessel occlusion: basilar artery occlusion patients.

Author

Heit, Jeremy Josef, Chaudhary, Neeraj, Mascitelli, Justin R., Al-Kawaz, Mais, Baker, Amanda, Bulsara, Ketan R., Burkhardt, Jan Karl, Marden, Franklin A., Raper, Daniel, Tjoumakaris, Stavropoula I., Schirmer, Clemens M., and Hetts, Steven W.

Subjects
MEDICAL protocols, CONSENSUS (Social sciences), BASILAR artery, NEUROSURGERY, PATIENTS, MEDICAL personnel, BLOOD vessels, COMPUTED tomography, ENDOVASCULAR surgery, EMERGENCY medical services, TREATMENT effectiveness, ISCHEMIC stroke, MEDICAL research, ARTERIAL occlusions, STROKE, EVIDENCE-based medicine, EXPERTISE, THROMBECTOMY
Abstract

Background Endovascular therapy (EVT) dramatically improves clinical outcomes for patients with anterior circulation emergent large vessel occlusion (ELVO) strokes. With recent publication of two randomized controlled trials in favor of EVT for basilar artery occlusions, the Society of NeuroInterventional Surgery (SNIS) Standards and Guidelines Committee provides this focused update for the existing SNIS guideline, 'Current endovascular strategies for posterior circulation large vessel occlusion stroke.' Methods A structured literature review and analysis of studies related to posterior circulation large vessel occlusion (basilar or vertebral artery) strokes treated by EVT was performed. Based on the strength and quality of the evidence, recommendations were made by consensus of the writing committee, with additional input from the full SNIS Standards and Guidelines Committee and the SNIS Board of Directors. Results Based on the results of the most recent randomized, controlled trials on EVT for basilar or vertebral artery occlusion, the expert panel agreed on the following recommendations. For patients presenting with an acute ischemic stroke due to an acute basilar or vertebral artery occlusion confirmed on CT angiography, National Institutes of Health Stroke Scale (NIHSS) score of ≥6, posterior circulation Alberta Stroke Program Early CT Score (PC-ASPECTS) ≥6, and age 18--89 years: (1) thrombectomy is indicated within 12 hours since last known well (class I, level B-R); (2) thrombectomy is reasonable within 12--24 hours from the last known well (class IIa, level B-R); (3) thrombectomy may be considered on a case by case basis for patients presenting beyond 24 hours since last known well (class IIb, level C-EO). In addition, thrombectomy may be considered on a case by case basis for patients aged <18 years or >89 years on a case by case basis (class IIb, level C-EO). Conclusions The indications for EVT of ELVO strokes continue to expand and now include patients with basilar artery occlusion. Further prospective, randomized controlled trials are warranted to elucidate the efficacy and safety of EVT in populations not included in this set of recommendations, and to confirm long term outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

31. The feasibility of mechanical thrombectomy versus medical management for acute stroke with a large ischemic territory

Author

Aslan, Assala, primary, Abuzahra, Saad, additional, Adeeb, Nimer, additional, Musmar, Basel, additional, Salim, Hamza A, additional, Kandregula, Sandeep, additional, Dmytriw, Adam A, additional, Griessenauer, Christoph J, additional, De Alba, Luis, additional, Arevalo, Octavio, additional, Burkhardt, Jan Karl, additional, Pereira, Vitor M, additional, Jabbour, Pascal, additional, Guthikonda, Bharat, additional, and Cuellar, Hugo H, additional

Published
2024
Full Text
View/download PDF

32. General Versus Nongeneral Anesthesia for Middle Meningeal Artery Embolization for Chronic Subdural Hematomas: Multicenter Propensity Score Matched Study

Author

Salem, Mohamed M., primary, Sioutas, Georgios S., additional, Khalife, Jane, additional, Kuybu, Okkes, additional, Caroll, Kate, additional, Nguyen Hoang, Alex, additional, Baig, Ammad A., additional, Salih, Mira, additional, Khorasanizadeh, Mirhojjat, additional, Baker, Cordell, additional, Mendez, Aldo A., additional, Cortez, Gustavo, additional, Abecassis, Zachary A., additional, Rodriguez, Juan F. Ruiz, additional, Davies, Jason M., additional, Narayanan, Sandra, additional, Cawley, C. Michael, additional, Riina, Howard A., additional, Moore, Justin M., additional, Spiotta, Alejandro M., additional, Khalessi, Alexander A., additional, Howard, Brian M., additional, Hanel, Ricardo, additional, Tanweer, Omar, additional, Tonetti, Daniel A., additional, Siddiqui, Adnan H., additional, Lang, Michael J., additional, Levy, Elad I., additional, Kan, Peter, additional, Jovin, Tudor, additional, Grandhi, Ramesh, additional, Srinivasan, Visish M., additional, Ogilvy, Christopher S., additional, Gross, Bradley A., additional, Jankowitz, Brian T., additional, Thomas, Ajith J., additional, Levitt, Michael R., additional, and Burkhardt, Jan-Karl, additional

Published
2024
Full Text
View/download PDF

33. Abstract TP5: Impact of Race on Outcomes in the Endovascular and Microsurgical Treatment in Patients With Intracranial Aneurysms: Analysis of the Stroke Thrombectomy and Aneurysm Registry

Author

Matsukawa, Hidetoshi, primary, Uchida, Kazutaka, additional, Sowlat, Mohammad-Mahdi, additional, Elawady, Sameh Samir, additional, Cunningham, Conor, additional, Alawieh, Ali, additional, Al Kasab, Sami, additional, Jabbour, Pascal, additional, Mascitelli, Justin, additional, Levitt, Michael, additional, Cuellar, Hugo, additional, Brinjikji, Waleed, additional, Samaniego, Edgar, additional, Burkhardt, Jan-Karl, additional, Ezzeldin, Mohamad, additional, Kan, Peter, additional, Fox, W. Christopher, additional, Moss, Mark, additional, Grandhi, Ramesh, additional, Altschul, David J, additional, Spiotta, Alejandro M, additional, and Yoshimura, Shinichi, additional

Published
2024
Full Text
View/download PDF

34. Abstract WMP95: Anesthesia Modality in Endovascular Treatment for Distal Medium Vessel Occlusion Stroke: Intention-to-Treat Matched Analysis

Author

Mohammaden, Mahmoud H, primary, Dohiem, Mohamed F, additional, Abdelhamid, Hend M, additional, matsoukas, stavros, additional, Schuldt, Braxton R, additional, Johanna, Fifi, additional, Kuybu, Okkes, additional, Gross, Bradley, additional, Al-Bayati, Alhamza R, additional, Dolia, Jaydevsinh, additional, Olive-Gadea, Marta, additional, Rodrigo-Gisbert, Marc, additional, Requena, Manuel, additional, Monteiro, Andre, additional, Yu, Si, additional, Siegler, James E, additional, Farooqui, Mudassir, additional, Vivanco-Suarez, Juan, additional, Ortega-Gutierrez, Santiago, additional, Cortez, Gustavo, additional, Hanel, Ricardo, additional, Hassan, Ameer E, additional, Nguyen, Thanh, additional, AbdalKader, Mohamad, additional, Klein, Piers, additional, Salem, Mohamed M, additional, Burkhardt, Jan-Karl, additional, Jankowitz, Brian, additional, Colasurdo, Marco, additional, Kan, Peter, additional, Hafeez, Muhammad, additional, Tanweer, Omar, additional, Peng, Sophia, additional, Alaraj, Ali A, additional, Siddiqui, Adnan, additional, Nogueira, Raul G, additional, and Haussen, Diogo C, additional

Published
2024
Full Text
View/download PDF

35. Abstract WP198: Balloon Guide Catheter Impact on Angiographic and Clinical Outcomes in Distal Medium Vessel Occlusion Strokes Undergoing Thrombectomy

Author

Mohammaden, Mahmoud H, primary, Dolia, Jaydevsinh, additional, Abdelhamid, Hend M, additional, matsoukas, stavros, additional, Schuldt, Braxton R, additional, Johanna, Fifi, additional, Kuybu, Okkes, additional, Al-Bayati, Alhamza, additional, Olive-Gadea, Marta, additional, Rodrigo-Gisbert, Marc, additional, Requena, Manuel, additional, Monteiro, Andre, additional, Moreira Ferreira, Felipe, additional, Yu, Si, additional, Siegler, James E, additional, Farooqui, Mudassir, additional, Vivanco-Suarez, Juan, additional, Ortega-Gutierrez, Santiago, additional, Cortez, Gustavo, additional, Hanel, Ricardo, additional, Hassan, Ameer E, additional, Nguyen, Thanh, additional, AbdalKader, Mohamad, additional, Klein, Piers, additional, Salem, Mohamed, additional, Burkhardt, Jan-Karl, additional, Jankowitz, Brian, additional, Colasurdo, Marco, additional, Kan, Peter, additional, Hafeez, Muhammad, additional, Tanweer, Omar, additional, Peng, Sophia, additional, Alaraj, Ali A, additional, Siddiqui, Adnan, additional, Nogueira, Raul G, additional, and Haussen, Diogo C, additional

Published
2024
Full Text
View/download PDF

36. Microsurgical Clipping of Unruptured Anterior Circulation Aneurysms—A Global Multicenter Investigation of Perioperative Outcomes

Author

Sauvigny, Jennifer, primary, Drexler, Richard, additional, Pantel, Tobias F., additional, Ricklefs, Franz L., additional, Catapano, Joshua S., additional, Wanebo, John E., additional, Lawton, Michael T., additional, Sanchin, Aminaa, additional, Hecht, Nils, additional, Vajkoczy, Peter, additional, Raygor, Kunal, additional, Tonetti, Daniel, additional, Abla, Adib, additional, El Naamani, Kareem, additional, Tjoumakaris, Stavropoula I., additional, Jabbour, Pascal, additional, Jankowitz, Brian T., additional, Salem, Mohamed M., additional, Burkhardt, Jan-Karl, additional, Wagner, Arthur, additional, Wostrack, Maria, additional, Gempt, Jens, additional, Meyer, Bernhard, additional, Gaub, Michael, additional, Mascitelli, Justin R., additional, Dodier, Philippe, additional, Bavinzski, Gerhard, additional, Roessler, Karl, additional, Stroh, Nico, additional, Gmeiner, Matthias, additional, Gruber, Andreas, additional, Figueiredo, Eberval G., additional, Coelho, Antonio Carlos Samaia da Silva, additional, Bervitskiy, Anatoliy V., additional, Anisimov, Egor D., additional, Rzaev, Jamil A., additional, Krenzlin, Harald, additional, Keric, Naureen, additional, Ringel, Florian, additional, Park, Dougho, additional, Kim, Mun-Chul, additional, Marcati, Eleonora, additional, Cenzato, Marco, additional, Krause, Linda, additional, Westphal, Manfred, additional, Dührsen, Lasse, additional, and Sauvigny, Thomas, additional

Published
2024
Full Text
View/download PDF

37. The impact of postoperative aspirin in patients undergoing Woven EndoBridge: a multicenter, institutional, propensity score-matched analysis

Author

Dmytriw, Adam A, primary, Musmar, Basel, additional, Salim, Hamza, additional, Aslan, Assala, additional, Cancelliere, Nicole M, additional, McLellan, Rachel M, additional, Algin, Oktay, additional, Ghozy, Sherief, additional, Dibas, Mahmoud, additional, Lay, Sovann V, additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Carnevale, Joseph Anthony, additional, Saliou, Guillaume, additional, Mastorakos, Panagiotis, additional, El Naamani, Kareem, additional, Shotar, Eimad, additional, Premat, Kevin, additional, Möhlenbruch, Markus A, additional, Kral, Michael, additional, Doron, Omer, additional, Chung, Charlotte, additional, Salem, Mohamed M, additional, Lylyk, Ivan, additional, Foreman, Paul M, additional, Vachhani, Jay A, additional, Shaikh, Hamza, additional, Župančić, Vedran, additional, Hafeez, Muhammad Ubaid, additional, Catapano, Joshua S, additional, Waqas, Muhammad, additional, Tutino, Vincent M, additional, Ibrahim, Mohamed K, additional, Mohammed, Marwa A, additional, Imamoglu, Cetin, additional, Bayrak, Ahmet, additional, Rabinov, James D, additional, Ren, Yifan, additional, Schirmer, Clemens M, additional, Piano, Mariangela, additional, Kuhn, Anna Luisa, additional, Michelozzi, Caterina, additional, Elens, Stephanie, additional, Hasan, Zuha, additional, Starke, Robert M, additional, Hassan, Ameer E, additional, Ogilvie, Mark, additional, Nguyen, Anh, additional, Jones, Jesse, additional, Brinjikji, Waleed, additional, Nawka, Marie Teresa, additional, Psychogios, Marios-Nikos, additional, Ulfert, Christian, additional, Diestro, Jose Danilo Bengzon, additional, Pukenas, Bryan, additional, Burkhardt, Jan Karl, additional, Huynh, Thien J, additional, Martinez-Gutierrez, Juan Carlos, additional, Essibayi, Muhammed Amir, additional, Sheth, Sunil A, additional, Spiegel, Gary, additional, Tawk, Rabih, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S, additional, Pero, Guglielmo, additional, Nossek, Erez, additional, Raz, Eytan, additional, Killer-Oberpfalzer, Monika, additional, Griessenauer, Christoph J, additional, Asadi, Hamed, additional, Siddiqui, Adnan H, additional, Brook, Allan L, additional, Altschul, David, additional, Ducruet, Andrew F, additional, Albuquerque, Felipe C, additional, Regenhardt, Robert W, additional, Stapleton, Christopher J, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth Reddy, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A, additional, Tjoumakaris, Stavropoula I, additional, Clarençon, Frédéric, additional, Limbucci, Nicola, additional, Cuellar, Hugo H, additional, Jabbour, Pascal M, additional, Pereira, Vitor M, additional, Patel, Aman B, additional, and Adeeb, Nimer, additional

Published
2024
Full Text
View/download PDF

44. The Impact of Preprocedural Platelet Function Testing on Periprocedural Complication Rates Associated With Pipeline Flow Diversion: An International Multicenter Study

Author

Vranic, Justin E., Dmytriw, Adam A., Berglar, Inka K., Alotaibi, Naif M., Cancelliere, Nicole M., Stapleton, Christopher J., Rabinov, James D., Harker, Pablo, Gupta, Rajiv, Bernstock, Joshua D., Koch, Matthew J., Raymond, Scott B., Mascitelli, Justin R., Patterson, T. Tyler, Seinfeld, Joshua, White, Andrew, Case, David, Roark, Christopher, Gandhi, Chirag D., Al-Mufti, Fawaz, Cooper, Jared, Matouk, Charles, Sujijantarat, Nanthiya, Devia, Diego A., Ocampo-Navia, Maria I., Villamizar-Torres, Daniel E., Puentes, Juan C., Salem, Mohamed M., Baig, Ammad, El Namaani, Kareem, Kühn, Anna Luisa, Pukenas, Bryan, Jankowitz, Brian T., Burkhardt, Jan Karl, Siddiqui, Adnan, Jabbour, Pascal, Singh, Jasmeet, Puri, Ajit S., Regenhardt, Robert W., Mendes Pereira, Vitor, and Patel, Aman B.

Published
2024
Full Text
View/download PDF

49. Early Experience With the Dual-Mode Radial-Access Catheter Armadillo in Neuroendovascular Procedures via the Radial Approach: A Multicenter Study of 71 Patients.

Author

El Naamani, Kareem, Mastorakos, Panagiotis, Teichner, Eric M., Sioutas, Georgios S., Salem, Mohamed M., Tjoumakaris, Stavropoula I., Gooch, M. Reid, Rosenwasser, Robert H., Srinivasan, Visish, Jankowitz, Brian T., Burkhardt, Jan-Karl, Jabbour, Pascal M., Theiss, Peter, and Alaraj, Ali

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results