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2. Lower rate of major bleeding in very high risk patients undergoing left atrial appendage occlusion: A propensity score–matched comparison with direct oral anticoagulant

Author

Magnocavallo, Michele, Della Rocca, Domenico G., Vetta, Giampaolo, Mohanty, Sanghamitra, Gianni, Carola, Polselli, Marco, Rossi, Pietro, Parlavecchio, Antonio, Fazia, Mirco Vincenzo La, Guarracini, Fabrizio, De Vuono, Francesco, Bisignani, Antonio, Pannone, Luigi, Raposeiras-Roubín, Sergio, Lochy, Stijn, Cauti, Filippo Maria, Burkhardt, J. David, Boveda, Serge, Sarkozy, Andrea, Sorgente, Antonio, Bianchi, Stefano, Chierchia, Gian-Battista, de Asmundis, Carlo, Al-Ahmad, Amin, Di Biase, Luigi, Horton, Rodney P., and Natale, Andrea

Published
2024
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6. Prevalence, Management, and Outcome of Atrial Fibrillation and Other Supraventricular Arrhythmias in COVID-19 Patients

Author

Magnocavallo, Michele, Vetta, Giampaolo, Della Rocca, Domenico G., Gianni, Carola, Mohanty, Sanghamitra, Bassiouny, Mohamed, Di Lullo, Luca, Del Prete, Armando, Cirone, Donatello, Lavalle, Carlo, Chimenti, Cristina, Al-Ahmad, Amin, Burkhardt, J. David, Gallinghouse, G. Joseph, Sanchez, Javier E., Horton, Rodney P., Di Biase, Luigi, and Natale, Andrea

Published
2022
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7. Predictive Score for Identifying Survival and Recurrence Risk Profiles in Patients Undergoing Ventricular Tachycardia Ablation

Author

Vergara, Pasquale, Tzou, Wendy S, Tung, Roderick, Brombin, Chiara, Nonis, Alessandro, Vaseghi, Marmar, Frankel, David S, Di Biase, Luigi, Tedrow, Usha, Mathuria, Nilesh, Nakahara, Shiro, Tholakanahalli, Venkat, Bunch, T Jared, Weiss, J Peter, Dickfeld, Timm, Lakireddy, Dhanunjaya, Burkhardt, J David, Santangeli, Pasquale, Callans, David, Natale, Andrea, Marchlinski, Francis, Stevenson, William G, Shivkumar, Kalyanam, Sauer, William H, and Della Bella, Paolo

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Heart Disease, Cardiovascular, Good Health and Well Being, Age Factors, Aged, Aged, 80 and over, Catheter Ablation, Cohort Studies, Databases, Factual, Decision Trees, Electrocardiography, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Predictive Value of Tests, ROC Curve, Recurrence, Retrospective Studies, Risk Assessment, Severity of Illness Index, Sex Factors, Stroke Volume, Survival Analysis, Tachycardia, Ventricular, Time Factors, Treatment Outcome, cardiomyopathies, catheter ablation, mortality, risk assessment, ventricular tachycardia, Cardiorespiratory Medicine and Haematology, Medical Physiology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences, Medical physiology
Abstract

BackgroundSeveral distinct risk factors for arrhythmia recurrence and mortality following ventricular tachycardia (VT) ablation have been described. The effect of concurrent risk factors has not been assessed so far; thus, it is not yet possible to estimate these risks for a patient with several comorbidities. The aim of the study was to identify specific risk groups for mortality and VT recurrence using the Survival Tree (ST) analysis method.MethodsIn 1251 patients 16 demographic, clinical and procedure-related variables were evaluated as potential prognostic factors using ST analysis using a recursive partitioning algorithm that searches for relationships among variables. Survival time and time to VT recurrence in groups derived from ST analysis were compared by a log-rank test. A random forest analysis was then run to extract a variable importance index and internally validate the ST models.ResultsLeft ventricular ejection fraction, implantable cardioverter defibrillator/cardiac resynchronization device, previous ablation were, in hierarchical order, identified by ST analysis as best predictors of VT recurrence, while left ventricular ejection fraction, previous ablation, Electrical storm were identified as best predictors of mortality. Three groups with significantly different survival rates were identified. Among the high-risk group, 65.0% patients were survived and 52.1% patients were free from VT recurrence; within the medium- and low-risk groups, 84.0% and 97.2% patients survived, 72.4% and 88.4% were free from VT recurrence, respectively.ConclusionsOur study is the first to derive and validate a decisional model that provides estimates of VT recurrence and mortality with an effective classification tree. Preprocedure risk stratification could help optimize periprocedural and postprocedural care.

Published
2018

8. Outcomes of Catheter Ablation of Ventricular Tachycardia Based on Etiology in Nonischemic Heart Disease: An International Ventricular Tachycardia Ablation Center Collaborative Study.

Author

Vaseghi, Marmar, Hu, Tiffany Y, Tung, Roderick, Vergara, Pasquale, Frankel, David S, Di Biase, Luigi, Tedrow, Usha B, Gornbein, Jeffrey A, Yu, Ricky, Mathuria, Nilesh, Nakahara, Shiro, Tzou, Wendy S, Sauer, William H, Burkhardt, J David, Tholakanahalli, Venkatakrishna N, Dickfeld, Timm-Michael, Weiss, J Peter, Bunch, T Jared, Reddy, Madhu, Callans, David J, Lakkireddy, Dhanunjaya R, Natale, Andrea, Marchlinski, Francis E, Stevenson, William G, Della Bella, Paolo, and Shivkumar, Kalyanam

Subjects
Humans, Tachycardia, Ventricular, Cardiomyopathies, Catheter Ablation, Treatment Outcome, Retrospective Studies, Adult, Aged, Middle Aged, Female, Male, ablation, arrhythmogenic right ventricular cardiomyopathy, myocarditis, nonischemic, sarcoidosis, valvular, ventricular tachycardia, Rare Diseases, Autoimmune Disease, Cardiovascular, Heart Disease, Clinical Research, Cardiorespiratory Medicine and Haematology, Clinical Sciences
Abstract

ObjectivesThis study sought to characterize ventricular tachycardia (VT) ablation outcomes across nonischemic cardiomyopathy (NICM) etiologies and adjust these outcomes by patient-related comorbidities that could explain differences in arrhythmia recurrence rates.BackgroundOutcomes of catheter ablation of VT in patients with NICM could be related to etiology of NICM.MethodsData from 2,075 patients with structural heart disease referred for catheter ablation of VT from 12 international centers was retrospectively analyzed. Patient characteristics and outcomes were noted for the 6 most common NICM etiologies. Multivariable Cox proportional hazards modeling was used to adjust for potential confounders.ResultsOf 780 NICM patients (57 ± 14 years of age, 18% women, left ventricular ejection fraction 37 ± 13%), underlying prevalence was 66% for dilated idiopathic cardiomyopathy (DICM), 13% for arrhythmogenic right ventricular cardiomyopathy (ARVC), 6% for valvular cardiomyopathy, 6% for myocarditis, 4% for hypertrophic cardiomyopathy, and 3% for sarcoidosis. One-year freedom from VT was 69%, and freedom from VT, heart transplantation, and death was 62%. On unadjusted competing risk analysis, VT ablation in ARVC demonstrated superior VT-free survival (82%) versus DICM (p ≤ 0.01). Valvular cardiomyopathy had the poorest unadjusted VT-free survival, at 47% (p < 0.01). After adjusting for comorbidities, including age, heart failure severity, ejection fraction, prior ablation, and antiarrhythmic medication use, myocarditis, ARVC, and DICM demonstrated similar outcomes, whereas hypertrophic cardiomyopathy, valvular cardiomyopathy, and sarcoidosis had the highest risk of VT recurrence.ConclusionsCatheter ablation of VT in NICM is effective. Etiology of NICM is a significant predictor of outcomes, with ARVC, myocarditis, and DICM having similar but superior outcomes to hypertrophic cardiomyopathy, valvular cardiomyopathy, and sarcoidosis, after adjusting for potential covariates.

Published
2018

9. Reduced heart failure hospitalizations and improved quality of life in cardiac amyloidosis patients undergoing atrial fibrillation ablation

Author

Pierucci, N, primary, La Fazia, V M, additional, Gianni, C, additional, Torlapati, P G, additional, Della Rocca, D, additional, Horton, R, additional, Al Hamad, A, additional, Burkhardt, J D, additional, Mariani, M V, additional, Chimenti, C, additional, Di Biase, L, additional, Lavalle, C, additional, and Natale, A, additional

Published
2024
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10. Impact of catheter ablation on erectile dysfunction in atrial fibrillation patients

Author

La Fazia, V, primary, Pierucci, N, additional, Gianni, C, additional, Torlapati, P G, additional, Mohanty, S, additional, Della Rocca, D G, additional, Massaro, G, additional, Bode, W, additional, Bassiouny, M, additional, Burkhardt, J D, additional, Horton, R, additional, Al-Ahmad, A, additional, Sangiorgi, G M, additional, Di Biase, L, additional, and Natale, A, additional

Published
2024
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11. Prevalence of non pulmonary vein triggers and pulmonary pressure change in atrial fibrillation ablation for cardiac amyloidosis patients

Author

La Fazia, V, primary, Pierucci, N, additional, Gianni, C, additional, Torlapati, P G, additional, Mohanty, S, additional, Della Rocca, D G, additional, Gigante, C, additional, Bode, W, additional, Bassiouny, M, additional, Burkhardt, J D, additional, Gallinghouse, G, additional, Horton, R, additional, Al-Ahmad, A, additional, Di Biase, L, additional, and Natale, A, additional

Published
2024
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12. Efficacy of catheter ablation in patients with persistent atrial fibrillation on chronic ibrutinib therapy

Author

Pierucci, N, primary, La Fazia, V M, additional, Gianni, C, additional, Della Rocca, D G, additional, Mohanty, S, additional, Torlapati, P G, additional, Mariani, M V, additional, Burkhardt, J D, additional, Horton, R P, additional, Al-Ahmad, A, additional, Chimenti, C, additional, Di Biase, L, additional, Lavalle, C, additional, and Natale, A, additional

Published
2024
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13. Wide Complex Tachycardia

Author

Gianni, Carola, Chen, Qiong, Canpolat, Uğur, Della Rocca, Domenico G., Al-Ahmad, Amin, Burkhardt, J. David, Natale, Andrea, Toth, Peter P., Series Editor, Yan, Gan-Xin, editor, Kowey, Peter R., editor, and Antzelevitch, Charles, editor

Published
2020
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14. Incidence of Device-Related Thrombosis in Watchman Patients Undergoing a Genotype-Guided Antithrombotic Strategy

Author

Della Rocca, Domenico G., Horton, Rodney P., Di Biase, Luigi, Gianni, Carola, Trivedi, Chintan, Mohanty, Sanghamitra, Anannab, Alisara, Magnocavallo, Michele, Chen, Qiong, Tarantino, Nicola, Bassiouny, Mohamed, Lavalle, Carlo, Natale, Veronica N., Forleo, Giovanni B., Del Prete, Armando, Van Niekerk, Christoffel Johannes, Al-Ahmad, Amin, Burkhardt, J. David, Gallinghouse, G. Joseph, Sanchez, Javier E., Lakkireddy, Dhanunjaya, Gibson, Douglas N., and Natale, Andrea

Published
2021
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15. Radiofrequency Energy Applications Targeting Significant Residual Leaks After Watchman Implantation: A Prospective, Multicenter Experience

Author

Della Rocca, Domenico G., Murtaza, Ghulam, Di Biase, Luigi, Akella, Krishna, Krishnan, Subramaniam C., Magnocavallo, Michele, Mohanty, Sanghamitra, Gianni, Carola, Trivedi, Chintan, Lavalle, Carlo, Forleo, Giovanni B., Natale, Veronica N., Tarantino, Nicola, Romero, Jorge, Gopinathannair, Rakesh, Patel, Philip J., Bassiouny, Mohamed, Del Prete, Armando, Al-Ahmad, Amin, Burkhardt, J. David, Gallinghouse, G. Joseph, Sanchez, Javier E., Doshi, Shephal K., Horton, Rodney P., Lakkireddy, Dhanunjaya, and Natale, Andrea

Published
2021
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19. Do Virtual Environments Unleash Everyone’s Creative Potential?

Author

Bourgeois-Bougrine, S., Richard, P., Lubart, T., Burkhardt, J. M., Frantz, B., Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Bagnara, Sebastiano, editor, Tartaglia, Riccardo, editor, Albolino, Sara, editor, Alexander, Thomas, editor, and Fujita, Yushi, editor

Published
2019
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27. Freedom from recurrent ventricular tachycardia after catheter ablation is associated with improved survival in patients with structural heart disease: An International VT Ablation Center Collaborative Group study

Author

Tung, Roderick, Vaseghi, Marmar, Frankel, David S, Vergara, Pasquale, Di Biase, Luigi, Nagashima, Koichi, Yu, Ricky, Vangala, Sitaram, Tseng, Chi-Hong, Choi, Eue-Keun, Khurshid, Shaan, Patel, Mehul, Mathuria, Nilesh, Nakahara, Shiro, Tzou, Wendy S, Sauer, William H, Vakil, Kairav, Tedrow, Usha, Burkhardt, J David, Tholakanahalli, Venkatakrishna N, Saliaris, Anastasios, Dickfeld, Timm, Weiss, J Peter, Bunch, T Jared, Reddy, Madhu, Kanmanthareddy, Arun, Callans, David J, Lakkireddy, Dhanunjaya, Natale, Andrea, Marchlinski, Francis, Stevenson, William G, Della Bella, Paolo, and Shivkumar, Kalyanam

Subjects
Cardiovascular, Transplantation, Heart Disease, Good Health and Well Being, Aged, Body Surface Potential Mapping, Cardiomyopathies, Catheter Ablation, Defibrillators, Implantable, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prognosis, Recurrence, Retrospective Studies, Survival Rate, Tachycardia, Ventricular, United States, Ablation, Ventricular tachycardia, Biomedical Engineering, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology
Abstract

BackgroundThe impact of catheter ablation of ventricular tachycardia (VT) on all-cause mortality remains unknown.ObjectiveThe purpose of this study was to examine the association between VT recurrence after ablation and survival in patients with scar-related VT.MethodsAnalysis of 2061 patients with structural heart disease referred for catheter ablation of scar-related VT from 12 international centers was performed. Data on clinical and procedural variables, VT recurrence, and mortality were analyzed. Kaplan-Meier analysis was used to estimate freedom from recurrent VT, transplant, and death. Cox proportional hazards frailty models were used to analyze the effect of risk factors on VT recurrence and mortality.ResultsOne-year freedom from VT recurrence was 70% (72% in ischemic and 68% in nonischemic cardiomyopathy). Fifty-seven patients (3%) underwent cardiac transplantation, and 216 (10%) died during follow-up. At 1 year, the estimated rate of transplant and/or mortality was 15% (same for ischemic and nonischemic cardiomyopathy). Transplant-free survival was significantly higher in patients without VT recurrence than in those with recurrence (90% vs 71%, P

Published
2015

30. Evidence of relevant electrical connection between the left atrial appendage and the great cardiac vein during catheter ablation of atrial fibrillation

Author

Di Biase, Luigi, Romero, Jorge, Briceno, David, Valderrabano, Miguel, Sanchez, Javier E., Della Rocca, Domenico G., Mohanty, Prasant, Horton, Rodney, Gallinghouse, G. Joseph, Mohanty, Sanghamitra, Trivedi, Chintan, Beheiry, Salwa, Gianni, Carola, Elayi, Claude S., Burkhardt, J. David, and Natale, Andrea

Published
2019
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31. Safety and outcomes of catheter ablation for atrial fibrillation in adults with congenital heart disease: A multicenter registry study

Author

Liang, Jackson J., Frankel, David S., Parikh, Valay, Lakkireddy, Dhanujaya, Mohanty, Sanghamitra, Burkhardt, J. David, Natale, Andrea, Szilagyi, Judit, Gerstenfeld, Edward P., Moore, Jeremy P., Collins, Kathryn K., Kay, Joseph D., Santangeli, Pasquale, Marchlinski, Francis E., Sauer, William H., and Nguyen, Duy T.

Published
2019
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33. Variant of ventricular outflow tract ventricular arrhythmias requiring ablation from multiple sites: Intramural origin

Author

Di Biase, Luigi, Romero, Jorge, Zado, Erica S., Diaz, Juan Carlos, Gianni, Carola, Hranitzki, Patrick M., Sanchez, Javier E., Mohanty, Sanghamitra, Al-Ahmad, Amin, Mohanty, Prasant, Trivedi, Chintan, Della Rocca, Domenico, Santangeli, Pasquale, Burkhardt, J. David, Garcia, Fermin C., Marchlinski, Francis E., and Natale, Andrea

Published
2019
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35. Percutaneous left ventricular assist devices in ventricular tachycardia ablation: multicenter experience.

Author

Reddy, Yeruva, Chinitz, Larry, Mansour, Moussa, Bunch, T, Mahapatra, Srijoy, Swarup, Vijay, Di Biase, Luigi, Bommana, Sudharani, Atkins, Donita, Tung, Roderick, Burkhardt, J, Ruskin, Jeremy, Natale, Andrea, Lakkireddy, Dhanunjaya, and Shivkumar, Kalyanam

Subjects
catheter ablation, intra-aortic balloon pumping, tachycardia, ventricular, Aged, Cardiac Catheterization, Catheter Ablation, Echocardiography, Electrocardiography, Female, Follow-Up Studies, Hospital Mortality, Humans, Intra-Aortic Balloon Pumping, Male, Middle Aged, Prospective Studies, Tachycardia, Ventricular, Treatment Outcome, United States, Ventricular Function, Left
Abstract

BACKGROUND: Data on relative safety, efficacy, and role of different percutaneous left ventricular assist devices for hemodynamic support during the ventricular tachycardia (VT) ablation procedure are limited. METHODS AND RESULTS: We performed a multicenter, observational study from a prospective registry including all consecutive patients (N=66) undergoing VT ablation with a percutaneous left ventricular assist devices in 6 centers in the United States. Patients with intra-aortic balloon pump (IABP group; N=22) were compared with patients with either an Impella or a TandemHeart device (non-IABP group; N=44). There were no significant differences in the baseline characteristics between both the groups. In non-IABP group (1) more patients could undergo entrainment/activation mapping (82% versus 59%; P=0.046), (2) more number of unstable VTs could be mapped and ablated per patient (1.05±0.78 versus 0.32±0.48; P

Published
2014

36. The predictive value of compression rate on residual leak after left atrial appendage occlusion with watchman FLX

Author

La Fazia, V, primary, Gianni, C, additional, Pierucci, N, additional, Della Rocca, D G, additional, Mohanty, S, additional, Macdonald, B, additional, Mayedo, A, additional, Torlapati, G, additional, Bassiouny, M, additional, Al-Ahmad, A, additional, Gallinghouse, G J, additional, Burkhardt, J D, additional, Horton, R, additional, Di Biase, L, additional, and Natale, A, additional

Published
2023
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37. Distribution of triggers in the left atrial posterior wall in AF patients undergoing catheter ablation

Author

Mohanty, S, primary, La Fazia, V M, additional, Torlapati, P G, additional, Gianni, C A R O L A, additional, Macdonald, B, additional, Mayedo, A, additional, Della Rocca, D G, additional, Bassiouny, M, additional, Gallinghouse, G J, additional, Burkhardt, J D, additional, Horton, R, additional, Al-Ahmad, A, additional, Di Biase, L, additional, and Natale, A N D R E A, additional

Published
2023
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38. Prevalence of new-onset tricuspid regurgitation after leadless Micra pacemaker implantation

Author

La Fazia, V, primary, Gianni, C, additional, Pierucci, N, additional, Della Rocca, D G, additional, Mohanty, S, additional, Torlapati, G, additional, Al-Ahmad, A, additional, Bassiouny, M, additional, Gallinghouse, G J, additional, Horton, R, additional, Burkhardt, J D, additional, Lakkireddy, D, additional, Forleo, G B, additional, Di Biase, L, additional, and Natale, A, additional

Published
2023
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45. Prospective Multicenter Experience With Cooled Radiofrequency Ablation Using High Impedance Irrigant to Target Deep Myocardial Substrate Refractory to Standard Ablation

Author

Nguyen, Duy T., Tzou, Wendy S., Sandhu, Amneet, Gianni, Carola, Anter, Elad, Tung, Roderick, Valderrábano, Miguel, Hranitzky, Patrick, Soeijma, Kyoko, Saenz, Luis, Garcia, Fermin C., Tedrow, Usha B., Miller, John M., Gerstenfeld, Edward P., Burkhardt, J. David, Natale, Andrea, and Sauer, William H.

Published
2018
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46. Bailout Atrial Balloon Septoplasty to Overcome Challenging Left Atrial Transseptal Access for Catheter Ablation of Atrial Fibrillation

Author

Liang, Jackson J., Mohanty, Sanghamitra, Fahed, Joe, Muser, Daniele, Briceno, David F., Burkhardt, J. David, Arkles, Jeffrey S., Supple, Gregory E., Frankel, David S., Nazarian, Saman, Garcia, Fermin C., Callans, David J., Dixit, Sanjay, Di Biase, Luigi, Natale, Andrea, Marchlinski, Francis E., and Santangeli, Pasquale

Published
2018
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48. O-021 Concurrent middle meningeal artery embolization for treatment of chronic subdural hematomas

Author

Salah, W, primary, Baker, C, additional, Scoville, J, additional, Hunsaker, J, additional, Ogilvy, C, additional, Moore, J, additional, Riina, H, additional, Levy, E, additional, Spiotta, A, additional, Jankowitz, B, additional, Cawley, C, additional, Khalessi, A, additional, Tanweer, O, additional, Hanel, R, additional, Gross, B, additional, Kuybu, O, additional, Nguyen Hoang, A, additional, Baig, A, additional, Khorasanizadeh, M, additional, Mendez, A, additional, Cortez, G, additional, Davies, J, additional, Narayanan, S, additional, Howard, B, additional, Lang, M, additional, Siddiqui, A, additional, Thomas, A, additional, Kan, P, additional, Burkhardt, J, additional, Salem, M, additional, and Grandhi, R, additional

Published
2023
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49. P-014 Adjunctive middle meningeal artery embolization and surgical evacuation for chronic subdural hematomas: does timing matter?

Author

Sioutas, G, primary, Salem, M, additional, Kuybu, O, additional, Khalife, J, additional, Carroll, K, additional, Baker, C, additional, Hoang, A, additional, Cortez, G, additional, Abecassis, Z, additional, Hunsaker, J, additional, Rodriguez, J, additional, Mendez, A, additional, Narayanan, S, additional, Tanweer, O, additional, Hanel, R, additional, Lang, M, additional, Kan, P, additional, Grandhi, R, additional, Levitt, M, additional, Thomas, A, additional, Gross, B, additional, Srinivasan, V, additional, Jankowitz, B, additional, and Burkhardt, J, additional

Published
2023
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50. O-063 First U.S. multicenter experience using the pipeline flex embolization device with shield technology for treatment of intracranial aneurysms

Author

Kuhn, A, primary, Singh, J, additional, Abdelsalam, A, additional, Saini, V, additional, Burks, J, additional, Cortez, G, additional, Abbas, R, additional, Pervez, M, additional, Saei, H, additional, Burke, S, additional, Salem, M, additional, Vivanco-Suarez, J, additional, Kutcher-Diaz, R, additional, Bounajem, M, additional, Naragum, V, additional, Massari, F, additional, Marwah, S, additional, Gounis, M, additional, Hassan, A, additional, Malek, A, additional, Dabus, G, additional, Linfante, I, additional, Tjoumakaris, S, additional, Jabbour, P, additional, Burkhardt, J, additional, Jankowitz, B, additional, Mudassir, F, additional, Ortega Gutierrez, S, additional, Grandhi, R, additional, Hanel, R, additional, Starke, R, additional, and Puri, A, additional

Published
2023
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