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Nanostructured solid boron-hydrogen compounds have been suggested as target and fuel for laser fusion, offering improved laser-plasma coupling, avoiding cryogenic fuel handling and fuel pre-compression and ultimately allowing a transit from DT- to aneutronic pB- fusion power production. We describe the scaling of the different energy loss channels ({\alpha}-particle escape, bremsstrahlung, hydrodynamic expansion work, electron heat conduction) with mixed fuel composition using partial inverse gains (Q's) which allow a simple superposition of losses. This highlights in particular the negative synergy between these loss-channels for such mixed fuels: the dominance of bremsstrahlung over fusion power at low temperatures forces a shift of operation to higher ones, where the plasma gets more transparent to {\alpha}-particles, and hydrodynamic and heat conduction losses increase strongly. The use of mixed fuels therefore does not eliminate the need for strong precompression of the fuel: in fact, it renders achieving burning plasma conditions much more difficult, if not impossible. A recent suggestion to use tamping of the fuel by cladding with a heavy metal would only reduce hydrodynamic expansion losses significantly if the cladding could cover most of the fuel surface, in competition with access to laser radiation. But even if tamping were perfect, this would not reduce the remaining three loss channels - in fact it would have a negative effect on burn propagation, as the escaping energy would not heat surrounding fuel, but only the cladding material., Comment: 19 pages, 9 figures; affiliation of authors added in revised version

In the most recent note on Marvel Fusion's concept for a laser driven pB reactor without compression, Ruhl and Korn consider the volumetric energy balance of fusion reactions vs. bremsstrahlung losses in a mixed fuel (DT and pB) environment and claim the satisfaction of this necessary "ideal ignition" condition. Their results are based, however, on improper assumptions about the deposition of fusion energy in the plasma. Correcting for them, we show that the quoted composition of their fuel (a solid boron composite, binding high concentrations of D, T and p) would actually preclude ignition due to the high bremsstrahlung losses associated with the presence of boron. To facilitate ignition, Ruhl and Korn also consider the reduction of the bremsstrahlung losses by confining the radiation in the optically thin fuel region by high Z walls. They suggest to preload this region with radiation so that the radiation temperature equals approximately that of the plasma constituents $T_{r} \approx T_{e} \approx T_{i}$. We show that in this set-up the radiation energy - neglected in these considerations - would, however, vastly exceed the thermal energy of the plasma and actually dominate the ignition energy requirements., Comment: 6 pages, 1 figure