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14 results on '"Burggraaff, J. M."'

1. Determinants of successful lifestyle change during a 6-month preconception lifestyle intervention in women with obesity and infertility

Author

Karsten, Matty D. A., van Oers, Anne M., Groen, Henk, Mutsaerts, Meike A. Q., van Poppel, Mireille N. M., Geelen, Anouk, van de Beek, Cornelieke, Painter, Rebecca C., Mol, Ben W. J., Roseboom, Tessa J., Hoek, Annemieke, Burggraaff, J. M., Kuchenbecker, W. K. H., Perquin, D. A. M., Koks, C. A. M., van Golde, R., Kaaijk, E. M., Schierbeek, J. M., Oosterhuis, G. J. E., Broekmans, F. J., Vogel, N. E. A., Lambalk, C. B., van der Veen, F., Klijn, N. F., Mercelina, P. E. A. M., van Kasteren, Y. M., Nap, A. W., Mulder, R. J. A. B., Gondrie, E. T. C. M., de Bruin, J. P., Obstetrie & Gynaecologie, MUMC+: MA Medische Staf Obstetrie Gynaecologie (9), RS: GROW - R4 - Reproductive and Perinatal Medicine, Reproductive Origins of Adult Health and Disease (ROAHD), Value, Affordability and Sustainability (VALUE), Public and occupational health, Pediatric surgery, Obstetrics and gynaecology, Amsterdam Reproduction & Development (AR&D), ACS - Atherosclerosis & ischemic syndromes, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Plastic, Reconstructive and Hand Surgery, APH - Aging & Later Life, APH - Health Behaviors & Chronic Diseases, Graduate School, Obstetrics and Gynaecology, and Epidemiology and Data Science

Subjects
Counseling, Male, 0301 basic medicine, Gerontology, Lifestyle intervention, DIABETES PREVENTION PROGRAM, TERM WEIGHT-LOSS, Nutrition and Disease, Psychological intervention, Medicine (miscellaneous), Overweight, 0302 clinical medicine, Weight loss, Voeding en Ziekte, SOCIOECONOMIC-STATUS, PREDICTORS, Determinants, Nutrition and Dietetics, Preconception, Original Contribution, 3. Good health, Weight Reduction Programs, PREGNANCY, Female, medicine.symptom, Adult, Infertility, Adolescent, 030209 endocrinology & metabolism, HEALTH BEHAVIOR, Health Promotion, CLASSIFICATION, Young Adult, 03 medical and health sciences, Intervention (counseling), Weight Loss, CORONARY RISK-FACTORS, medicine, Humans, Obesity, Exercise, Life Style, Socioeconomic status, VLAG, Pregnancy, 030109 nutrition & dietetics, OVERWEIGHT, business.industry, Feeding Behavior, ADULTS, medicine.disease, business, Program Evaluation
Abstract

Purpose To identify demographic, (bio)physical, behavioral, and psychological determinants of successful lifestyle change and program completion by performing a secondary analysis of the intervention arm of a randomized-controlled trial, investigating a preconception lifestyle intervention. Methods The 6-month lifestyle intervention consisted of dietary counseling, physical activity, and behavioral modification, and was aimed at 5–10% weight loss. We operationalized successful lifestyle change as successful weight loss (≥ 5% weight/BMI ≤ 29 kg/m2), weight loss in kilograms, a reduction in energy intake, and an increase in physical activity during the intervention program. We performed logistic and mixed-effect regression analyses to identify baseline factors that were associated with successful change or program completion. Results Women with higher external eating behavior scores had higher odds of successful weight loss (OR 1.10, 95% CI 1.05–1.16). Women with the previous dietetic support lost 0.94 kg less during the intervention period (95% CI 0.01–1.87 kg). Women with higher self-efficacy reduced energy intake more than women with lower self-efficacy (p

Published
2019
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2. An economic analysis of induction of labour and expectant monitoring in women with gestational hypertension or pre-eclampsia at term (HYPITAT trial)

Author

Vijgen, S MC, Koopmans, C M, Opmeer, B C, Groen, H, Bijlenga, D, Aarnoudse, J G, Bekedam, D J, Van Den Berg, P P, De Boer, K, Burggraaff, J M, Bloemenkamp, K WM, Drogtrop, A P, Franx, A, De Groot, C JM, Huisjes, A JM, Kwee, A, Van Loon, A J, Lub, A, Papatsonis, D NM, Van Der Post, J AM, Roumen, F JME, Scheepers, H CJ, Stigter, R H, Willekes, C, Mol, B WJ, and Van Pampus, M G

Published
2010
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3. Determinants of successful lifestyle change during a 6-month preconception lifestyle intervention in women with obesity and infertility

Author

MS Verloskunde, MS VPG/Gynaecologie, UMC Utrecht, Child Health, Circulatory Health, Karsten, Matty D.A., van Oers, Anne M., Groen, Henk, Mutsaerts, Meike A.Q., van Poppel, Mireille N.M., Geelen, Anouk, van de Beek, Cornelieke, Painter, Rebecca C., Mol, Ben W.J., Roseboom, Tessa J., Hoek, Annemieke, Burggraaff, J. M., Kuchenbecker, W. K.H., Perquin, D. A.M., Koks, C. A.M., van Golde, R., Kaaijk, E. M., Schierbeek, J. M., Oosterhuis, G. J.E., Broekmans, F. J., Vogel, N. E.A., Lambalk, C. B., van der Veen, F., Klijn, N. F., Mercelina, P. E.A.M., van Kasteren, Y. M., Nap, A. W., Mulder, R. J.A.B., Gondrie, E. T.C.M., de Bruin, J. P., the LIFEstyle study group, MS Verloskunde, MS VPG/Gynaecologie, UMC Utrecht, Child Health, Circulatory Health, Karsten, Matty D.A., van Oers, Anne M., Groen, Henk, Mutsaerts, Meike A.Q., van Poppel, Mireille N.M., Geelen, Anouk, van de Beek, Cornelieke, Painter, Rebecca C., Mol, Ben W.J., Roseboom, Tessa J., Hoek, Annemieke, Burggraaff, J. M., Kuchenbecker, W. K.H., Perquin, D. A.M., Koks, C. A.M., van Golde, R., Kaaijk, E. M., Schierbeek, J. M., Oosterhuis, G. J.E., Broekmans, F. J., Vogel, N. E.A., Lambalk, C. B., van der Veen, F., Klijn, N. F., Mercelina, P. E.A.M., van Kasteren, Y. M., Nap, A. W., Mulder, R. J.A.B., Gondrie, E. T.C.M., de Bruin, J. P., and the LIFEstyle study group

Published
2019

4. Effectiveness of lifestyle intervention in subgroups of obese infertile women : a subgroup analysis of a RCT

Author

Oers, A. M., Henk Groen, Mutsaerts, M. A. Q., Burggraaff, J. M., Kuchenbecker, W. K. H., Perquin, D. A. M., Koks, C. A. M., Golde, R., Kaaijk, E. M., Schierbeek, J. M., Oosterhuis, G. J. E., Broekmans, F. J., Vogel, N. E. A., Land, J. A., Mol, B. W. J., Hoek, A., and LIFEstyle study group

Subjects
Journal Article
Abstract

STUDY QUESTION: Do age, ovulatory status, severity of obesity and body fat distribution affect the effectiveness of lifestyle intervention in obese infertile women? SUMMARY ANSWER: We did not identify a subgroup in which lifestyle intervention increased the healthy live birth rate however it did increase the natural conception rate in anovulatory obese infertile women. WHAT IS KNOWN ALREADY: Obese women are at increased risk of infertility and are less likely to conceive after infertility treatment. We previously demonstrated that a 6-month lifestyle intervention preceding infertility treatment did not increase the rate of healthy live births (vaginal live birth of a healthy singleton at term) within 24 months of follow-up as compared to prompt infertility treatment in obese infertile women. Natural conceptions occurred more frequently in women who received a 6-month lifestyle intervention preceding infertility treatment. STUDY DESIGN, SIZE, DURATION: This is a secondary analysis of a multicentre RCT (randomized controlled trial), the LIFEstyle study. Between 2009 and 2012, 577 obese infertile women were randomly assigned to a 6-month lifestyle intervention followed by infertility treatment (intervention group) or to prompt infertility treatment (control group). Subgroups were predefined in the study protocol, based on frequently used cut-off values in the literature: age (≥36 or

Published
2016

5. Cost-effectiveness of a structured lifestyle program in overweight and obese subfertile women. Preliminary data from a randomised controlled trial - the LIFEstyle study

Author

van Oers, A. M., Mutsaerts, M. A. Q., Burggraaff, J. M., Kuchenbecker, W. K. H., Perquin, D. A. M., Koks, C. A. M., Van Golde, R., Kaaijk, E. M., Schierbeek, J. M., Oosterhuis, G. J. E., Broekmans, F. J., Land, J. A., Mol, B. W., Hoek, A., Groen, H., Reproductive Origins of Adult Health and Disease (ROAHD), and Methods in Medicines evaluation & Outcomes research (M2O)

Published
2014

6. The effectiveness of a structured lifestyle program in overweight and obese subfertile women. Preliminary data from a randomised controlled trial (LIFEstyle study)

Author

Mutsaerts, M. A. Q., Van Oers, A. M., Groen, H., Burggraaff, J. M., Kuchenbecker, W. K. H., Perquin, D. A. M., Koks, C. A. M., Van Golde, R., Kaaijk, E. M., Schierbeek, J. M., Oosterhuis, G. J. E., Broekmans, F. J., Land, J. A., Mol, B. W., Hoek, A., Methods in Medicines evaluation & Outcomes research (M2O), and Reproductive Origins of Adult Health and Disease (ROAHD)

Published
2014

7. Effectiveness of lifestyle intervention in subgroups of obese infertile women : a subgroup analysis of a RCT

Author

van Oers, A M, Groen, H, Mutsaerts, M A Q, Burggraaff, J M, Kuchenbecker, W K H, Perquin, D A M, Koks, C A M, van Golde, R, Kaaijk, E M, Schierbeek, J M, Oosterhuis, G J E, Broekmans, F J, Vogel, N E A, Land, J A, Mol, B W J, Hoek, A, LIFEstyle study group, van Oers, A M, Groen, H, Mutsaerts, M A Q, Burggraaff, J M, Kuchenbecker, W K H, Perquin, D A M, Koks, C A M, van Golde, R, Kaaijk, E M, Schierbeek, J M, Oosterhuis, G J E, Broekmans, F J, Vogel, N E A, Land, J A, Mol, B W J, Hoek, A, and LIFEstyle study group

Published
2016

8. Effectiveness of lifestyle intervention in subgroups of obese infertile women: a subgroup analysis of a RCT

Author

MS VPG/Gynaecologie, Circulatory Health, Child Health, van Oers, A M, Groen, H, Mutsaerts, M A Q, Burggraaff, J M, Kuchenbecker, W K H, Perquin, D A M, Koks, C A M, van Golde, R, Kaaijk, E M, Schierbeek, J M, Oosterhuis, G J E, Broekmans, F J, Vogel, N E A, Land, J A, Mol, B W J, Hoek, A, LIFEstyle study group, MS VPG/Gynaecologie, Circulatory Health, Child Health, van Oers, A M, Groen, H, Mutsaerts, M A Q, Burggraaff, J M, Kuchenbecker, W K H, Perquin, D A M, Koks, C A M, van Golde, R, Kaaijk, E M, Schierbeek, J M, Oosterhuis, G J E, Broekmans, F J, Vogel, N E A, Land, J A, Mol, B W J, Hoek, A, and LIFEstyle study group

Published
2016

9. Liever inleiden dan afwachten bij aterme zwangerschapshypertensie en milde preëclampsie: HYPITAT-studie*

Author

Koopmans, C. M., Bijlenga, D., Groen, H., Vijgen, S. M. C., Aarnoudse, J. G., Bekedam, D. J., van den Berg, P. P., de Boer, K., Burggraaff, J. M., Bloemenkamp, K. W. M., Drogtrop, A. P., Franx, A., de Groot, C. J. M., Huisjes, A. J. M., Kwee, A., van Loon, A. J., Lub, A., Papatsonis, D. N. M., van der Post, J. A. M., Roumen, F. J. M. E., Scheepers, H. C. J., Willekes, C., Mol, B. W. J., van Pampus, M. G., Obstetrics and gynaecology, ICaR - Ischemia and repair, Science in Healthy Ageing & healthcaRE (SHARE), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Reproductive Origins of Adult Health and Disease (ROAHD), Other departments, Amsterdam Reproduction & Development (AR&D), Obstetrics and Gynaecology, and Amsterdam Public Health

Subjects
reproductive and urinary physiology
Abstract

OBJECTIVE: To investigate what would benefit women with mild full-term pregnancy-related hypertension most: induction of labour or expectant monitoring, from the perspective of clinical effectiveness, maternal quality of life, and costs. DESIGN: Randomised clinical trial. Trial registration number ISRCTN08132825. METHODS: We undertook a multicentre randomised controlled trial in 38 hospitals in the Netherlands between October 2005 and March 2008. We enrolled patients with a singleton pregnancy in cephalic presentation at 36-41 weeks' gestation, who had gestational hypertension or mild preeclampsia. Participants were randomly allocated to receive either induction of labour or expectant monitoring. The primary outcome was a composite measure of poor maternal outcome, defined as maternal mortality, maternal morbidity (eclampsia, 'haemolysis, elevated liver enzymes, low platelets' (HELLP) syndrome, pulmonary oedema, thrombo-embolic disease and abruptio placentae), progression to severe hypertension or proteinuria, and major postpartum haemorrhage. Secondary outcomes were mode of delivery, neonatal outcome, maternal quality of life and costs. Analysis was by intention to treat. RESULTS: A total of 756 patients were allocated to receive induction of labour (n = 377 patients) or expectant monitoring (n = 379). No cases of maternal or neonatal death or eclampsia were recorded. Development of poor maternal outcome was significantly lower in the induction of labour group (117 women) than the expectant monitoring group (166 women) (31% versus 44%; relative risk 0.71 (95% CI: 0.59-0.86); p < 0.001). The caesarean section rate was lower among women in the induction of labour group (n = 54) compared to women in the expectant monitoring group (n = 72) (14% versus 19%; relative risk 0.75 (95% CI: 0.55-1.04)< p = 0.085). Neonatal outcomes and quality of life were comparable between both groups. Induction of labour is a cost saving strategy (difference euro 831). CONCLUSION: For women with full-term gestational hypertension and pre-eclampsia, induction of labour is associated with improved maternal outcome and lower costs, without the additional risk of a caesarean section being necessary

Published
2010

10. Cost-effectiveness analysis of lifestyle intervention in obese infertile women.

Author

van Oers, A. M., Mutsaerts, M. A. Q., Burggraaff, J. M., Kuchenbecker, W. K. H., Perquin, D. A. M., Koks, C. A. M., van Golde, R., Kaaijk, E. M., Schierbeek, J. M., Klijn, N. F., van Kasteren, Y. M., Land, J. A., Mol, B. W. J., Hoek, A., Groen, H., and LIFEstyle study group

Subjects
COST effectiveness, LIFESTYLES, INFERTILITY treatment, OVERWEIGHT women, OBESITY, HEALTH promotion, OBESITY treatment, CRYOPRESERVATION of organs, tissues, etc., FERTILIZATION in vitro, OBESITY complications, BIRTH rate, EMBRYO transfer, FAMILIES, LONGITUDINAL method, INFERTILITY, EVALUATION of medical care, MEDICAL care costs, INDUCED ovulation, PREGNANCY, WEIGHT loss, BODY mass index, HUMAN research subjects, PATIENT dropouts, DISEASE complications, ECONOMICS
Abstract

Study Question: What is the cost-effectiveness of lifestyle intervention preceding infertility treatment in obese infertile women?Summary Answer: Lifestyle intervention preceding infertility treatment as compared to prompt infertility treatment in obese infertile women is not a cost-effective strategy in terms of healthy live birth rate within 24 months after randomization, but is more likely to be cost-effective using a longer follow-up period and live birth rate as endpoint.What Is Known Already: In infertile couples, obesity decreases conception chances. We previously showed that lifestyle intervention prior to infertility treatment in obese infertile women did not increase the healthy singleton vaginal live birth rate at term, but increased natural conceptions, especially in anovulatory women. Cost-effectiveness analyses could provide relevant additional information to guide decisions regarding offering a lifestyle intervention to obese infertile women.Study Design, Size, Duration: The cost-effectiveness of lifestyle intervention preceding infertility treatment compared to prompt infertility treatment was evaluated based on data of a previous RCT, the LIFEstyle study. The primary outcome for effectiveness was the vaginal birth of a healthy singleton at term within 24 months after randomization (the healthy live birth rate). The economic evaluation was performed from a hospital perspective and included direct medical costs of the lifestyle intervention, infertility treatments, medication and pregnancy in the intervention and control group. In addition, we performed exploratory cost-effectiveness analyses of scenarios with additional effectiveness outcomes (overall live birth within 24 months and overall live birth conceived within 24 months) and of subgroups, i.e. of ovulatory and anovulatory women, women <36 years and ≥36 years of age and of completers of the lifestyle intervention. Bootstrap analyses were performed to assess the uncertainty surrounding cost-effectiveness.Participants/materials, Settings, Methods: Infertile women with a BMI of ≥29 kg/m2 (no upper limit) were allocated to a 6-month lifestyle intervention programme preceding infertility treatment (intervention group, n = 290) or to prompt infertility treatment (control group, n = 287). After excluding women who withdrew informed consent or who were lost to follow-up we included 280 women in the intervention group and 284 women in the control group in the analysis.Main Results and the Role Of Chance: Total mean costs per woman in the intervention group within 24 months after randomization were €4324 (SD €4276) versus €5603 (SD €4632) in the control group (cost difference of -€1278, P < 0.05). Healthy live birth rates were 27 and 35% in the intervention group and the control group, respectively (effect difference of -8.1%, P < 0.05), resulting in an incremental cost-effectiveness ratio of €15 845 per additional percentage increase of the healthy live birth rate. Mean costs per healthy live birth event were €15 932 in the intervention group and €15 912 in the control group. Exploratory scenario analyses showed that after changing the effectiveness outcome to all live births conceived within 24 months, irrespective of delivery within or after 24 months, cost-effectiveness of the lifestyle intervention improved. Using this effectiveness outcome, the probability that lifestyle intervention preceding infertility treatment was cost-effective in anovulatory women was 40%, in completers of the lifestyle intervention 39%, and in women ≥36 years 29%.Limitations, Reasons For Caution: In contrast to the study protocol, we were not able to perform the analysis from a societal perspective. Besides the primary outcome of the LIFEstyle study, we performed exploratory analyses using outcomes observed at longer follow-up times and we evaluated subgroups of women; the trial was not powered on these additional outcomes or subgroup analyses.Wider Implications Of the Findings: Cost-effectiveness of a lifestyle intervention is more likely for longer follow-up times, and with live births conceived within 24 months as the effectiveness outcome. This effect was most profound in anovulatory women, in completers of the lifestyle intervention and in women ≥36 years old. This result indicates that the follow-up period of lifestyle interventions in obese infertile women is important. The scenario analyses performed in this study suggest that offering and reimbursing lifestyle intervention programmes in certain patient categories may be cost-effective and it provides directions for future research in this field.Study Funding/competing Interest(s): The study was supported by a grant from ZonMw, the Dutch Organization for Health Research and Development (50-50110-96-518). The department of obstetrics and gynaecology of the UMCG received an unrestricted educational grant from Ferring pharmaceuticals BV, The Netherlands. B.W.J.M. is a consultant for ObsEva, Geneva.Trial Registration Number: The LIFEstyle RCT was registered at the Dutch trial registry (NTR 1530). http://www.trialregister.nl/trialreg/admin/rctview.asp?TC = 1530. [ABSTRACT FROM AUTHOR]

Published
2017
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13. An economic analysis of induction of labour and expectant monitoring in women with gestational hypertension or pre-eclampsia at term (HYPITAT trial).

Author

Vijgen SM, Koopmans CM, Opmeer BC, Groen H, Bijlenga D, Aarnoudse JG, Bekedam DJ, van den Berg PP, de Boer K, Burggraaff JM, Bloemenkamp KW, Drogtrop AP, Franx A, de Groot CJ, Huisjes AJ, Kwee A, van Loon AJ, Lub A, Papatsonis DN, van der Post JA, Roumen FJ, Scheepers HC, Stigter RH, Willekes C, Mol BW, and Van Pampus MG

Subjects
Cost of Illness, Cost-Benefit Analysis, Female, Health Resources economics, Humans, Hypertension, Pregnancy-Induced therapy, Length of Stay, Netherlands, Pre-Eclampsia therapy, Pregnancy, Hypertension, Pregnancy-Induced economics, Labor, Induced economics, Pre-Eclampsia economics, Watchful Waiting economics
Abstract

Objective: To assess the economic consequences of labour induction compared with expectant monitoring in women with gestational hypertension or pre-eclampsia at term., Design: An economic analysis alongside the Hypertension and Pre-eclampsia Intervention Trial At Term (HYPITAT)., Setting: Obstetric departments of six university and 32 teaching and district hospitals in the Netherlands., Population: Women diagnosed with gestational hypertension or pre-eclampsia between 36(+0) and 41(+0) weeks of gestation, randomly allocated to either induction of labour or expectant monitoring., Methods: A trial-based cost-effectiveness analysis was performed from a societal perspective during a 1-year time horizon., Main Outcome Measures: One-year costs were estimated and health outcomes were expressed as the prevalence of poor maternal outcome defined as either maternal complications or progression to severe disease., Results: The average costs of induction of labour (n = 377) were €7077 versus €7908 for expectant monitoring (n = 379), with an average difference of -€831 (95% CI -€1561 to -€144). This 11% difference predominantly originated from the antepartum period: per woman costs were €1259 for induction versus €2700 for expectant monitoring. During delivery, more costs were generated following induction (€2190) compared with expectant monitoring (€1210). No substantial differences were found in the postpartum, follow-up and for non-medical costs., Conclusion: In women with gestational hypertension or mild pre-eclampsia at term, induction of labour is less costly than expectant monitoring because of differences in resource use in the antepartum period. As the trial already demonstrated that induction of labour results in less progression to severe disease without resulting in a higher caesarean section rate, both clinical and economic consequences are in favour of induction of labour in these women., Trial Registration: The trial has been registered in the clinical trial register as ISRCTN08132825., (© 2010 The Authors Journal compilation © RCOG 2010 BJOG An International Journal of Obstetrics and Gynaecology.)

Published
2010
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