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5. Factors affecting overall survival and disease-free survival after surgery for hepatocellular carcinoma: a nomogram-based prognostic model—a Western European multicenter study

Author

Masuda, Yoshio, Yeo, Mark Hao Xuan, Burdio, Fernando, Sanchez-Velazquez, Patricia, Perez-Xaus, Marc, Pelegrina, Amalia, Koh, Ye Xin, Di Martino, Marcello, Goh, Brian K.P., Tan, Ek Khoon, Teo, Jin Yao, Romano, Fabrizio, Famularo, Simone, Ferrari, Cecilia, Griseri, Guido, Piardi, Tullio, Sommacale, Daniele, Gianotti, Luca, Molfino, Sarah, Baiocchi, Gianluca, and Ielpo, Benedetto

Published
2024
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7. IRON: A retrospective international multicenter study on robotic versus laparoscopic versus open approach in gallbladder cancer

Author

Ielpo, Benedetto, Vittoria d’Addetta, Maria, Burdio, Fernando, Sanchez-Velazquez, Patricia, Vellalta, Gemma, Cremona, Simone, Villamonte, Maria, Morelli, Luca, Furbetta, Niccoló, Di Franco, Gregorio, Comandatore, Annalisa, Mastrangelo, Mattia, Mazzone, Chiara, Masetti, Michele, Offi, Maria Fortuna, Geraldi, Eleonora, Aldrighetti, Luca, Ingallinella, Sara, Ratti, Francesca, Rosso, Edoardo, De Blasi, Vito, Anselmo, Alessandro, Conte, Luigi Eduardo, Memeo, Riccardo, Delvecchio, Antonella, Sukandy, Iswanto, Moraldi, Luca, Grazi, Gian Luca, Spampinato, Marcello G., D'Ugo, Stefano, Heng Chiow, Adrian Kah, Yi Yee, Francis Zheng, Tan, Hiang Jin, Thiruchelvam, Nita, Lancellotti, Francesco, Satyadas, Thomas, Fedi, Massimo, De Vincenti, Rosita, Leo, Francesca, Pesi, Benedetta, Belli, Andrea, Izzo, Francesco, Cutolo, Carmen, Romano, Fabrizio, Scotti, Mauro Alessandro, Carissimi, Francesca, Garancini, Mattia, Ciulli, Cristina, Mazzola, Michele, Ferrari, Giovanni, Zironda, Andrea, Giani, Alessandro, Giuliani, Giuseppe, Federica Dorma, Maria Pia, Guerra, Francesco, Di Marino, Michele, Coratti, Andrea, Mina, Elisa, Romanzi, Andrea, Prieto, Mikel, Perfecto, Arkaitz, Ioannidis, Orestis, Lombardeas, Odysseas, Ardito, Francesco, Giuliante, Felice, Lopez-Lopez, Victor, Robles-Campos, Ricardo, Martinie, John, Mccarron, Frances, Romito, Raffaele, Nicolosi, Filadelfio Massimiliano, Ben Dhaou, Anis, Chamekh, Atef, Rezgui, Bochra, Pacilli, Mario, Pavone, Giovanna, Tartaglia, Nicola, Gupta, Rahul, Grego, Davide Giovanni, Ricci, Claudio, Pata, Francesco, Nardo, Bruno, Facundo, Helena, Guevara, Oscar, Lorenzin, Dario, Guglielmi, Alfredo, Ruzzenente, Andrea, Valle, Valentina, Alberto, Mangano, Giulianotti, PierCristoforo, Vicente, Emilio, Ferri, Valentina, Avella, Pasquale, Calise, Fulvio, Rocca, Aldo, Bianchi, Paolo, Rompianesi, Gianluca, Troisi, Roberto I., Donadon, Matteo, di Martino, Marcello, Podda, Mauro, Pisanu, Adolfo, Torzilli, Guido, Vittoria d'Addetta, Maria, Di Martino, Marcello, and Giulianotti, Pier Cristoforo

Published
2024
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10. A machine learning predictive model for recurrence of resected distal cholangiocarcinoma: Development and validation of predictive model using artificial intelligence

Author

Perez, Marc, Palnaes Hansen, Carsten, Burdio, Fernando, Sanchez-Velázquez, Patricia, Giuliani, Antonio, Lancellotti, Francesco, de Liguori-Carino, Nicola, Malleo, Giuseppe, Marchegiani, Giovanni, Podda, Mauro, Pisanu, Adolfo, De Luca, Giuseppe Massimiliano, Anselmo, Alessandro, Siragusa, Leandro, Kobbelgaard Burgdorf, Stefan, Tschuor, Christoph, Cacciaguerra, Andrea Benedetti, Koh, Ye Xin, Masuda, Yoshio, Hao Xuan, Mark Yeo, Seeger, Nico, Breitenstein, Stefan, Grochola, Filip Lukasz, Di Martino, Marcello, Secanella, Luis, Busquets, Juli, Dorcaratto, Dimitri, Mora-Oliver, Isabel, Ingallinella, Sara, Salvia, Roberto, Abu Hilal, Mohammad, Aldrighetti, Luca, and Ielpo, Benedetto

Published
2024
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12. Repeated pancreatic resection for pancreatic metastases from renal cell Carcinoma: A Spanish multicenter study (PANMEKID)

Author

Rojas-Holguín, Adela, Fondevila-Campo, Constantino, Sanjuanbenito, Alfonso, Fabregat-Prous, Joan, Secanella-Medayo, Luís, Rotellar-Sastre, Fernando, Pardo-Sánchez, Fernando, Prieto-Calvo, Mikel, Marín-Ortega, Héctor, Sánchez-Cabús, Santiago, Diez-Valladares, Luis, Alonso-Casado, Óscar, González-Serrano, Carmen, Rodríguez-Sanjuan, Juan Carlos, García-Plaza, Gabriel, Jaén-Torrejimeno, Isabel, Suárez-Muñoz, Miguel Ángel, Becerra-Massare, Antonio, Rio, Paula Senra-del, Pando, Elizabeth, López-Andújar, Rafael, Muñoz-Forner, Elena, Rodriguez-López, Mario, Pereira, Fernando, Serrablo-Requejo, Alejandro, Turrión, Víctor Sánchez, Garrido, Manuel Jiménez, Burdío, Fernando, Martín-Pérez, Elena, Estevan-Estevan, Rafael, López-Guerra, Diego, Castell-Gómez, José, Salinas-Gómez, Javier, López-Baena, José Ángel, López-Ben, Santiago, Solar-García, Lorena, Pérez-Alonso, Alejandro J., Martínez-Insfran, Luis Alberto, Blas, Juan Luis, Cornejo, Marian, Gutierrez-Calvo, Alberto, Pozo, Carlos Domingo-del, Ochando-Cerdan, Federico, Muñoz-Bellvís, Luis, Rebollar-Saenz, José, Sánchez, Belinda, Jover, José María, Gómez-Bravo, Miguel Ángel, Ramia, José M., and Blanco-Fernández, Gerardo

Published
2024
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13. Pre-operative evaluation of spontaneous portosystemic shunts as a predictor of post-hepatectomy liver failure in patients undergoing liver resection for hepatocellular carcinoma

Author

Rompianesi, Gianluca, Han, Ho-Seong, Fusai, Giuseppe, Lopez-Ben, Santiago, Maestri, Marcello, Ercolani, Giorgio, Di Martino, Marcello, Diaz-Nieto, Rafael, Ielpo, Benedetto, Perez-Alonso, Alejandro, Morare, Nolitha, Casellas, Margarida, Gallotti, Anna, de la Hoz Rodriguez, Angela, Burdio, Fernando, Ravaioli, Federico, Venetucci, Pietro, Lo Bianco, Emanuela, Ceriello, Arianna, Montalti, Roberto, and Troisi, Roberto Ivan

Published
2024
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14. Robot-Assisted Versus Laparoscopic Distal Pancreatectomy in Patients with Resectable Pancreatic Cancer: An International, Retrospective, Cohort Study

Author

Chen, Jeffrey W., van Ramshorst, Tess M. E., Lof, Sanne, Al-Sarireh, Bilal, Bjornsson, Bergthor, Boggi, Ugo, Burdio, Fernando, Butturini, Giovanni, Casadei, Riccardo, Coratti, Andrea, D’Hondt, Mathieu, Dokmak, Safi, Edwin, Bjørn, Esposito, Alessandro, Fabre, Jean M., Ferrari, Giovanni, Ftériche, Fadhel S., Fusai, Giuseppe K., Groot Koerkamp, Bas, Hackert, Thilo, Jah, Asif, Jang, Jin-Young, Kauffmann, Emanuele F., Keck, Tobias, Manzoni, Alberto, Marino, Marco V., Molenaar, Quintus, Pando, Elizabeth, Pessaux, Patrick, Pietrabissa, Andrea, Soonawalla, Zahir, Sutcliffe, Robert P., Timmermann, Lea, White, Steven, Yip, Vincent S., Zerbi, Alessandro, Abu Hilal, Mohammad, and Besselink, Marc G.

Published
2023
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19. ASO Visual Abstract: Robot-Assisted Versus Laparoscopic Distal Pancreatectomy in Patients with Resectable Pancreatic Cancer—An International Retrospective Cohort Study

Author

Chen, Jeffrey W., van Ramshorst, Tess M. E., Lof, Sanne, Al-Sarireh, Bilal, Bjornsson, Bergthor, Boggi, Ugo, Burdio, Fernando, Butturini, Giovanni, Casadei, Riccardo, Coratti, Andrea, D’Hondt, Mathieu, Dokmak, Safi, Edwin, Bjørn, Esposito, Alessandro, Fabre, Jean M., Ferrari, Giovanni, Ftériche, Fadhel S., Fusai, Giuseppe K., Koerkamp, Bas Groot, Hackert, Thilo, Jah, Asif, Jang, Jin-Young, Kauffmann, Emanuele F., Keck, Tobias, Manzoni, Alberto, Marino, Marco V., Molenaar, Quintus, Rau, Elizabeth Pando, Pessaux, Patrick, Pietrabissa, Andrea, Soonawalla, Zahir, Sutcliffe, Robert P., Timmermann, Lea, White, Steven, Yip, Vincent S., Zerbi, Alessandro, Hilal, Mohammad Abu, and Besselink, Marc G.

Published
2023
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21. Use and outcome of minimally invasive pancreatic surgery in the European E-MIPS registry

Author

Vilhav, Caroline, Hartman, Vera, Kirkegård, Jakob, Sergeant, Gregory, Kleeff, Jörg, Coolsen, Marielle, Coppola, Roberto, Pauletti, Bruno, Mittermair, Christof, Tingstedt, Bobby, Erkan, Mert, Tomazic, Ales, Korkolis, Dimitris, van der Heijde, Nicky, Vissers, Frederique L., Manzoni, Alberto, Zimmitti, Giuseppe, Balsells, Joaquim, Berrevoet, Frederik, Bjornsson, Bergthor, van den Boezem, Peter, Boggi, Ugo, Bratlie, Svein O., Burdio, Fernando, Coratti, Andrea, D'Hondt, Mathieu, Del Pozo, Carlos D., Dokmak, Safi, Fara, Regis, Can, Mehmet F., Festen, Sebastiaan, Forgione, Antonello, Fristrup, Claus, Gaujoux, Sebastien, Groot Koerkamp, Bas, Hackert, Thilo, Khatkov, Igor E., Keck, Tobias, Seppänen, Hanna, Lips, Daan, Luyer, Misha, Pittau, Gabriella, Maglione, Manuel, Molenaar, I. Quintus, Pessaux, Patrick, Roeyen, Geert, Saint-Marc, Olivier, Cabus, Santiago S., van Santvoort, Hjalmar, van der Schelling, George, Serradilla-Martin, Mario, Souche, Francois-regis, Suarez Muñoz, Miguel Á., Marino, Marco V., Besselink, Marc G., and Abu Hilal, Mohammed

Published
2023
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25. Pancreatic metastases from renal cell carcinoma. Postoperative outcome after surgical treatment in a Spanish multicenter study (PANMEKID)

Author

Blanco-Fernández, Gerardo, Fondevila-Campo, Constantino, Sanjuanbenito, Alfonso, Fabregat-Prous, Joan, Secanella-Medayo, Luís, Rotellar-Sastre, Fernando, Pardo-Sánchez, Fernando, Prieto-Calvo, Mikel, Marín-Ortega, Héctor, Sánchez-Cabús, Santiago, Diez-Valladares, Luis, Alonso-Casado, Óscar, González-Serrano, Carmen, Rodríguez-Sanjuan, Juan Carlos, García-Plaza, Gabriel, Jaén-Torrejimeno, Isabel, Suárez-Muñoz, Miguel Ángel, Becerra-Massare, Antonio, Rio, Paula Senra-del, Pando, Elizabeth, López-Andújar, Rafael, Muñoz-Forner, Elena, Rodriguez-López, Mario, Pereira, Fernando, Serrablo-Requejo, Alejandro, Turrión, Víctor Sánchez, Garrido, Manuel Jiménez, Burdío, Fernando, Martín-Pérez, Elena, Estevan-Estevan, Rafael, López-Guerra, Diego, Castell-Gómez, José, Salinas-Gómez, Javier, López-Baena, José Ángel, López-Ben, Santiago, Solar-García, Lorena, Pérez-Alonso, Alejandro J., Martínez-Insfran, Luis Alberto, Blas, Juan Luis, Cornejo, Marian, Gutierrez-Calvo, Alberto, Pozo, Carlos Domingo-del, Ochando-Cerdan, Federico, Muñoz-Bellvís, Luis, Rebollar-Saenz, José, Sánchez, Belinda, Jover, José María, Gómez-Bravo, Miguel Ángel, Ramia, José M., and Rojas-Holguín, Adela

Published
2022
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27. Microwave versus radiofrequency ablation for the treatment of liver malignancies: a randomized controlled phase 2 trial

Author

Radosevic, Aleksandar, Quesada, Rita, Serlavos, Clara, Sánchez, Juan, Zugazaga, Ander, Sierra, Ana, Coll, Susana, Busto, Marcos, Aguilar, Guadalupe, Flores, Daniel, Arce, Javier, Maiques, José María, Garcia-Retortillo, Montserrat, Carrion, José Antonio, Visa, Laura, Villamonte, María, Pueyo, Eva, Berjano, Enrique, Trujillo, Macarena, Sánchez-Velázquez, Patricia, Grande, Luís, and Burdio, Fernando

Published
2022
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30. Electrical Conductivity Measurement in Human Liver Tissue: Assessment on Normal vs. Tumor Tissue and under In Vivo vs. Ex Vivo Conditions.

Author

Sarreshtehdari, Amirhossein, García-Sánchez, Tomás, Sánchez-Velázquez, Patricia, Ielpo, Benedetto, Berjano, Enrique, Villamonte, María, Moll, Xavier, and Burdio, Fernando

Subjects
ELECTRIC conductivity, ELECTRIC properties, CIRRHOSIS of the liver, ELECTRIC fields, LIVER tumors
Abstract

Background: This study evaluated electrical conductivity in human liver tissue in the 3–1000 kHz frequency range to compare normal versus tumor tissues under in vivo versus ex vivo conditions. Methods: Previous informed consent was obtained from twenty patients undergoing liver resection in whom liver electrical conductivity was measured during surgery and after resection. Result: We found higher electrical conductivity values in tumor tissues than in normal tissue in both in vivo (0.41 ± 0.10 vs. 0.13 ± 0.06 S/m) and ex vivo (0.27 ± 0.09 vs. 0.12 ± 0.07 S/m) conditions (at 3 kHz). The electric properties also showed a promising potential for distinguishing between different tissue types including metastasis, cholangiocarcinoma (CCA), hepatocellular carcinoma (HCC), hepatic cirrhosis, and normal liver (both in vivo and ex vivo). At 3 kHz, in vivo electrical conductivity for cholangiocarcinoma, HCC, and metastasis were 0.35, 0.42 ± 0.13, and 0.41 ± 0.08 S/m, respectively, which differed significantly from each other (p < 0.05). Conclusions: These findings could potentially improve liver disease diagnostics through electrical conductivity measurements and treatment techniques involving electric fields. Future research should focus on expanding the sample size to refine the categorization and comparison processes across diverse human liver tissue types. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Computational modeling of radiofrequency ablation with an internally cooled wet electrode

Author

Ewertowska, Elzbieta, Quesada-Diez, Rita, Radosevic, Aleksandar, Andaluz, Anna, Moll, Xavier, Berjano, Enrique, Burdio, Fernando, Trujillo, Macarena, Magjarevic, Ratko, Editor-in-chief, Ładyżyński, Piotr, Series editor, Ibrahim, Fatimah, Series editor, Lacković, Igor, Series editor, Rock, Emilio Sacristan, Series editor, Eskola, Hannu, editor, Väisänen, Outi, editor, Viik, Jari, editor, and Hyttinen, Jari, editor

Published
2018
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34. Factors affecting overall survival and disease-free survival after surgery for hepatocellular carcinoma: a nomogram-based prognostic model—a Western European multicenter study

Author

Masuda, Yoshio, primary, Yeo, Mark Hao Xuan, additional, Burdio, Fernando, additional, Sanchez-Velazquez, Patricia, additional, Perez-Xaus, Marc, additional, Pelegrina, Amalia, additional, Koh, Ye Xin, additional, Di Martino, Marcello, additional, Goh, Brian K.P., additional, Tan, Ek Khoon, additional, Teo, Jin Yao, additional, Romano, Fabrizio, additional, Famularo, Simone, additional, Ferrari, Cecilia, additional, Griseri, Guido, additional, Piardi, Tullio, additional, Sommacale, Daniele, additional, Gianotti, Luca, additional, Molfino, Sarah, additional, Baiocchi, Gianluca, additional, and Ielpo, Benedetto, additional

Published
2023
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38. Computational Study to Assess Whether the Heat Sink Effect of Blood Flow Inside the Portal Vein Could Thermally Protect Its Wall during RF-Assisted Resection

Author

González-Suárez, Ana, Trujillo, Macarena, Burdío, Fernando, Andaluz, Anna, Berjano, Enrique, MAGJAREVIC, Ratko, Editor-in-chief, Ładyzynsk, Piotr, Series editor, Ibrahim, Fatimah, Series editor, Lacković, Igor, Series editor, Rock, Emilio Sacristan, Series editor, and Vasic, Darko, editor

Published
2015
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39. Is occlusion of the main pancreatic duct by thermal ablation really safe? A surgical innovation assessed according to IDEAL recommendations

Author

Moll, Xavier, primary, Fondevila, Dolors, additional, García-Arnas, Félix, additional, Pérez, Juan J., additional, Ielpo, Benedetto, additional, Sánchez-Velázquez, Patricia, additional, Grande, Luis, additional, Jaume, Sofía, additional, Radosevic, Aleksandar, additional, Barranco, Luis, additional, Berjano, Enrique, additional, Burdio, Fernando, additional, and Andaluz, Anna, additional

Published
2023
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40. Robot-Assisted Versus Laparoscopic Distal Pancreatectomy in Patients with Resectable Pancreatic Cancer: An International, Retrospective, Cohort Study

Author

Chen, Jeffrey, van Ramshorst, Tess M. E., Lof, Sanne, Al-Sarireh, Bilal, Björnsson, Bergthor, Boggi, Ugo, Burdio, Fernando M., Butturini, Giovanni, Casadei, Riccardo, Coratti, Andrea, DHondt, Mathieu, Dokmak, Safi, Edwin, Bjorn, Esposito, Alessandro, Fabre, Jean M., Ferrari, Giovanni, Fteriche, Fadhel S., Fusai, Giuseppe K., Groot Koerkamp, Bas, Hackert, Thilo, Jah, Asif, Jang, Jin-Young, Kauffmann, Emanuele F., Keck, Tobias, Manzoni, Alberto, Marino, Marco V, Molenaar, Quintus, Pando, Elizabeth, Pessaux, Patrick, Pietrabissa, Andrea, Soonawalla, Zahir, Sutcliffe, Robert P., Timmermann, Lea, White, Steven, Yip, Vincent S., Zerbi, Alessandro, Abu Hilal, Mohammad, Besselink, Marc G., Chen, Jeffrey, van Ramshorst, Tess M. E., Lof, Sanne, Al-Sarireh, Bilal, Björnsson, Bergthor, Boggi, Ugo, Burdio, Fernando M., Butturini, Giovanni, Casadei, Riccardo, Coratti, Andrea, DHondt, Mathieu, Dokmak, Safi, Edwin, Bjorn, Esposito, Alessandro, Fabre, Jean M., Ferrari, Giovanni, Fteriche, Fadhel S., Fusai, Giuseppe K., Groot Koerkamp, Bas, Hackert, Thilo, Jah, Asif, Jang, Jin-Young, Kauffmann, Emanuele F., Keck, Tobias, Manzoni, Alberto, Marino, Marco V, Molenaar, Quintus, Pando, Elizabeth, Pessaux, Patrick, Pietrabissa, Andrea, Soonawalla, Zahir, Sutcliffe, Robert P., Timmermann, Lea, White, Steven, Yip, Vincent S., Zerbi, Alessandro, Abu Hilal, Mohammad, and Besselink, Marc G.

Abstract

BackgroundRobot-assisted distal pancreatectomy (RDP) is increasingly used as an alternative to laparoscopic distal pancreatectomy (LDP) in patients with resectable pancreatic cancer but comparative multicenter studies confirming the safety and efficacy of RDP are lacking.MethodsAn international, multicenter, retrospective, cohort study, including consecutive patients undergoing RDP and LDP for resectable pancreatic cancer in 33 experienced centers from 11 countries (2010-2019). The primary outcome was R0-resection. Secondary outcomes included lymph node yield, major complications, conversion rate, and overall survival.ResultsIn total, 542 patients after minimally invasive distal pancreatectomy were included: 103 RDP (19%) and 439 LDP (81%). The R0-resection rate was comparable (75.7% RDP vs. 69.3% LDP, p = 0.404). RDP was associated with longer operative time (290 vs. 240 min, p < 0.001), more vascular resections (7.6% vs. 2.7%, p = 0.030), lower conversion rate (4.9% vs. 17.3%, p = 0.001), more major complications (26.2% vs. 16.3%, p = 0.019), improved lymph node yield (18 vs. 16, p = 0.021), and longer hospital stay (10 vs. 8 days, p = 0.001). The 90-day mortality (1.9% vs. 0.7%, p = 0.268) and overall survival (median 28 vs. 31 months, p = 0.599) did not differ significantly between RDP and LDP, respectively.ConclusionsIn selected patients with resectable pancreatic cancer, RDP and LDP provide a comparable R0-resection rate and overall survival in experienced centers. Although the lymph node yield and conversion rate appeared favorable after RDP, LDP was associated with shorter operating time, less major complications, and shorter hospital stay. The specific benefits associated with each approach should be confirmed by multicenter, randomized trials.

Published
2023
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41. Benchmarking of robotic and laparoscopic spleen-preserving distal pancreatectomy by using two different methods

Author

van Ramshorst, Tess M. E., Giani, Alessandro, Mazzola, Michele, Dokmak, Safi, Fteriche, Fadhel Samir, Esposito, Alessandro, de Pastena, Matteo, Lof, Sanne, Edwin, Bjorn, Sahakyan, Mushegh, Boggi, Ugo, Kauffman, Emanuele Federico, Fabre, Jean Michel, Souche, Regis Francois, Zerbi, Alessandro, Butturini, Giovanni, Molenaar, Quintus, Al-Sarireh, Bilal, Marino, Marco V, Keck, Tobias, White, Steven A., Casadei, Riccardo, Burdio, Fernando, Björnsson, Bergthor, Soonawalla, Zahir, Koerkamp, Bas Groot, Fusai, Giuseppe Kito, Pessaux, Patrick, Jah, Asif, Pietrabissa, Andrea, Hackert, Thilo, DHondt, Mathieu, Pando, Elizabeth, Besselink, Marc G., Ferrari, Giovanni, Abu Hilaland, Mohammad, van Ramshorst, Tess M. E., Giani, Alessandro, Mazzola, Michele, Dokmak, Safi, Fteriche, Fadhel Samir, Esposito, Alessandro, de Pastena, Matteo, Lof, Sanne, Edwin, Bjorn, Sahakyan, Mushegh, Boggi, Ugo, Kauffman, Emanuele Federico, Fabre, Jean Michel, Souche, Regis Francois, Zerbi, Alessandro, Butturini, Giovanni, Molenaar, Quintus, Al-Sarireh, Bilal, Marino, Marco V, Keck, Tobias, White, Steven A., Casadei, Riccardo, Burdio, Fernando, Björnsson, Bergthor, Soonawalla, Zahir, Koerkamp, Bas Groot, Fusai, Giuseppe Kito, Pessaux, Patrick, Jah, Asif, Pietrabissa, Andrea, Hackert, Thilo, DHondt, Mathieu, Pando, Elizabeth, Besselink, Marc G., Ferrari, Giovanni, and Abu Hilaland, Mohammad

Abstract

Background Benchmarking is an important tool for quality comparison and improvement. However, no benchmark values are available for minimally invasive spleen-preserving distal pancreatectomy, either laparoscopically or robotically assisted. The aim of this study was to establish benchmarks for these techniques using two different methods. Methods Data from patients undergoing laparoscopically or robotically assisted spleen-preserving distal pancreatectomy were extracted from a multicentre database (2006-2019). Benchmarks for 10 outcomes were calculated using the Achievable Benchmark of Care (ABC) and best-patient-in-best-centre methods. Results Overall, 951 laparoscopically assisted (77.3 per cent) and 279 robotically assisted (22.7 per cent) procedures were included. Using the ABC method, the benchmarks for laparoscopically assisted and robotically assisted spleen-preserving distal pancreatectomy respectively were: 150 and 207 min for duration of operation, 55 and 100 ml for blood loss, 3.5 and 1.7 per cent for conversion, 0 and 1.7 per cent for failure to preserve the spleen, 27.3 and 34.0 per cent for overall morbidity, 5.1 and 3.3 per cent for major morbidity, 3.6 and 7.1 per cent for pancreatic fistula grade B/C, 5 and 6 days for duration of hospital stay, 2.9 and 5.4 per cent for readmissions, and 0 and 0 per cent for 90-day mortality. Best-patient-in-best-centre methodology revealed milder benchmark cut-offs for laparoscopically and robotically assisted procedures, with operating times of 254 and 262.5 min, blood loss of 150 and 195 ml, conversion rates of 5.8 and 8.2 per cent, rates of failure to salvage spleen of 29.9 and 27.3 per cent, overall morbidity rates of 62.7 and 55.7 per cent, major morbidity rates of 20.4 and 14 per cent, POPF B/C rates of 23.8 and 24.2 per cent, duration of hospital stay of 8 and 8 days, readmission rates of 20 and 15.1 per cent, and 90-day mortality rates of 0 and 0 per cent respectively. Conclusion Two benchmark methods for mi

Published
2023
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42. Learning Curves of Minimally Invasive Distal Pancreatectomy in Experienced Pancreatic Centers

Author

Lof, Sanne, Claassen, Linda, Hannink, Gerjon, Al-Sarireh, Bilal, Björnsson, Bergthor, Boggi, Ugo, Burdio, Fernando, Butturini, Giovanni, Capretti, Giovanni, Casadei, Riccardo, Dokmak, Safi, Edwin, Bjorn, Esposito, Alessandro, Fabre, Jean M., Ferrari, Giovanni, Fretland, Asmund A., Fteriche, Fadhel S., Fusai, Giuseppe K., Giardino, Alessandro, Groot Koerkamp, Bas, DHondt, Mathieu, Jah, Asif, Kamarajah, Sivesh K., Kauffmann, Emanuele F., Keck, Tobias, van Laarhoven, Stijn, Manzoni, Alberto, Marino, Marco V., Marudanayagam, Ravi, Molenaar, Izaak Q., Pessaux, Patrick, Rosso, Edoardo, Salvia, Roberto, Soonawalla, Zahir, Souche, Regis, White, Steven, van Workum, Frans, Zerbi, Alessandro, Rosman, Camiel, Stommel, Martijn W. J., Abu Hilal, Mohammed, Besselink, Marc G., Lof, Sanne, Claassen, Linda, Hannink, Gerjon, Al-Sarireh, Bilal, Björnsson, Bergthor, Boggi, Ugo, Burdio, Fernando, Butturini, Giovanni, Capretti, Giovanni, Casadei, Riccardo, Dokmak, Safi, Edwin, Bjorn, Esposito, Alessandro, Fabre, Jean M., Ferrari, Giovanni, Fretland, Asmund A., Fteriche, Fadhel S., Fusai, Giuseppe K., Giardino, Alessandro, Groot Koerkamp, Bas, DHondt, Mathieu, Jah, Asif, Kamarajah, Sivesh K., Kauffmann, Emanuele F., Keck, Tobias, van Laarhoven, Stijn, Manzoni, Alberto, Marino, Marco V., Marudanayagam, Ravi, Molenaar, Izaak Q., Pessaux, Patrick, Rosso, Edoardo, Salvia, Roberto, Soonawalla, Zahir, Souche, Regis, White, Steven, van Workum, Frans, Zerbi, Alessandro, Rosman, Camiel, Stommel, Martijn W. J., Abu Hilal, Mohammed, and Besselink, Marc G.

Abstract

IMPORTANCE Understanding the learning curve of a new complex surgical technique helps to reduce potential patient harm. Current series on the learning curve of minimally invasive distal pancreatectomy (MIDP) are mostly small, single-center series, thus providing limited data. OBJECTIVE To evaluate the length of pooled learning curves of MIDP in experienced centers. DESIGN, SETTING, AND PARTICIPANTS This international, multicenter, retrospective cohort study included MIDP procedures performed from January 1, 2006, through June 30, 2019, in 26 European centers from 8 countries that each performed more than 15 distal pancreatectomies annually, with an overall experience exceeding 50 MIDP procedures. Consecutive patients who underwent elective laparoscopic or robotic distal pancreatectomy for all indications were included. Data were analyzed between September 1, 2021, and May 1, 2022. EXPOSURES The learning curve for MIDP was estimated by pooling data from all centers. MAIN OUTCOMES AND MEASURES The learning curvewas assessed for the primary textbook outcome (TBO), which is a composite measure that reflects optimal outcome, and for surgical mastery. Generalized additive models and a 2-piece linear model with a break point were used to estimate the learning curve length of MIDP. Case mix-expected probabilities were plotted and compared with observed outcomes to assess the association of changing case mix with outcomes. The learning curve also was assessed for the secondary outcomes of operation time, intraoperative blood loss, conversion to open rate, and postoperative pancreatic fistula grade B/C. RESULTS From a total of 2610 MIDP procedures, the learning curve analysis was conducted on 2041 procedures (mean [SD] patient age, 58 [15.3] years; among 2040 with reported sex, 1249 were female [61.2%] and 791 male [38.8%]). The 2-piece model showed an increase and eventually a break point for TBO at 85 procedures (95% CI, 13-157 procedures), with a plateau TBO rate at 70%. T

Published
2023
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43. Use and outcome of minimally invasive pancreatic surgery in the European E-MIPS registry

Author

van der Heijde, Nicky, Vissers, Frederique L., Manzoni, Alberto, Zimmitti, Giuseppe, Balsells, Joaquim, Berrevoet, Frederik, Björnsson, Bergthor, van den Boezem, Peter, Boggi, Ugo, Bratlie, Svein O., Burdio, Fernando, Coratti, Andrea, DHondt, Mathieu, Del Pozo, Carlos D., Dokmak, Safi, Fara, Regis, Can, Mehmet F., Festen, Sebastiaan, Forgione, Antonello, Fristrup, Claus, Gaujoux, Sebastien, Koerkamp, Bas Groot, Hackert, Thilo, Khatkov, Igor E., Keck, Tobias, Seppanen, Hanna, Lips, Daan, Luyer, Misha, Pittau, Gabriella, Maglione, Manuel, Molenaar, I. Quintus, Pessaux, Patrick, Roeyen, Geert, St-Marc, Olivier, Cabus, Santiago S., van Santvoort, Hjalmar, van der Schelling, George, Serradilla-Martin, Mario, Souche, Francois-regis, Munoz, Miguel A. Suarez, Marino, Marco V, Besselink, Marc G., Abu Hilal, Mohammed, van der Heijde, Nicky, Vissers, Frederique L., Manzoni, Alberto, Zimmitti, Giuseppe, Balsells, Joaquim, Berrevoet, Frederik, Björnsson, Bergthor, van den Boezem, Peter, Boggi, Ugo, Bratlie, Svein O., Burdio, Fernando, Coratti, Andrea, DHondt, Mathieu, Del Pozo, Carlos D., Dokmak, Safi, Fara, Regis, Can, Mehmet F., Festen, Sebastiaan, Forgione, Antonello, Fristrup, Claus, Gaujoux, Sebastien, Koerkamp, Bas Groot, Hackert, Thilo, Khatkov, Igor E., Keck, Tobias, Seppanen, Hanna, Lips, Daan, Luyer, Misha, Pittau, Gabriella, Maglione, Manuel, Molenaar, I. Quintus, Pessaux, Patrick, Roeyen, Geert, St-Marc, Olivier, Cabus, Santiago S., van Santvoort, Hjalmar, van der Schelling, George, Serradilla-Martin, Mario, Souche, Francois-regis, Munoz, Miguel A. Suarez, Marino, Marco V, Besselink, Marc G., and Abu Hilal, Mohammed

Abstract

Background: The European registry for minimally invasive pancreatic surgery (E-MIPS) collects data on laparoscopic and robotic MIPS in low-and high-volume centers across Europe.Methods: Analysis of the first year (2019) of the E-MIPS registry, including minimally invasive distal pancreatectomy (MIDP) and minimally invasive pancreatoduodenectomy (MIPD). Primary outcome was 90-day mortality.Results: Overall, 959 patients from 54 centers in 15 countries were included, 558 patients underwent MIDP and 401 patients MIPD. Median volume of MIDP was 10 (7-20) and 9 (2-20) for MIPD. Median use of MIDP was 56.0% (IQR 39.0-77.3%) and median use of MIPD 27.7% (IQR 9.7-45.3%). MIDP was mostly performed laparoscopic (401/558, 71.9%) and MIPD mostly robotic (234/401, 58.3%). MIPD was performed in 50/54 (89.3%) centers, of which 15/50 (30.0%) performed >= 20 MIPD annually. This was 30/ 54 (55.6%) centers and 13/30 (43%) centers for MIPD respectively. Conversion rate was 10.9% for MIDP and 8.4% for MIPD. Overall 90 day mortality was 1.1% (n = 6) for MIDP and 3.7% (n = 15) for MIPD.Conclusion: Within the E-MIPS registry, MIDP is performed in about half of all patients, mostly using laparoscopy. MIPD is performed in about a quarter of patients, slightly more often using the robotic approach. A minority of centers met the Miami guideline volume criteria for MIPD.

Published
2023
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44. Robot-Assisted Versus Laparoscopic Distal Pancreatectomy in Patients with Resectable Pancreatic Cancer:An International, Retrospective, Cohort Study

Author

Chen, Jeffrey W, van Ramshorst, Tess M E, Lof, Sanne, Al-Sarireh, Bilal, Bjornsson, Bergthor, Boggi, Ugo, Burdio, Fernando, Butturini, Giovanni, Casadei, Riccardo, Coratti, Andrea, D'Hondt, Mathieu, Dokmak, Safi, Edwin, Bjørn, Esposito, Alessandro, Fabre, Jean M, Ferrari, Giovanni, Ftériche, Fadhel S, Fusai, Giuseppe K, Groot Koerkamp, Bas, Hackert, Thilo, Jah, Asif, Jang, Jin-Young, Kauffmann, Emanuele F, Keck, Tobias, Manzoni, Alberto, Marino, Marco V, Molenaar, Quintus, Pando, Elizabeth, Pessaux, Patrick, Pietrabissa, Andrea, Soonawalla, Zahir, Sutcliffe, Robert P, Timmermann, Lea, White, Steven, Yip, Vincent S, Zerbi, Alessandro, Abu Hilal, Mohammad, Besselink, Marc G, Chen, Jeffrey W, van Ramshorst, Tess M E, Lof, Sanne, Al-Sarireh, Bilal, Bjornsson, Bergthor, Boggi, Ugo, Burdio, Fernando, Butturini, Giovanni, Casadei, Riccardo, Coratti, Andrea, D'Hondt, Mathieu, Dokmak, Safi, Edwin, Bjørn, Esposito, Alessandro, Fabre, Jean M, Ferrari, Giovanni, Ftériche, Fadhel S, Fusai, Giuseppe K, Groot Koerkamp, Bas, Hackert, Thilo, Jah, Asif, Jang, Jin-Young, Kauffmann, Emanuele F, Keck, Tobias, Manzoni, Alberto, Marino, Marco V, Molenaar, Quintus, Pando, Elizabeth, Pessaux, Patrick, Pietrabissa, Andrea, Soonawalla, Zahir, Sutcliffe, Robert P, Timmermann, Lea, White, Steven, Yip, Vincent S, Zerbi, Alessandro, Abu Hilal, Mohammad, and Besselink, Marc G

Abstract

BACKGROUND: Robot-assisted distal pancreatectomy (RDP) is increasingly used as an alternative to laparoscopic distal pancreatectomy (LDP) in patients with resectable pancreatic cancer but comparative multicenter studies confirming the safety and efficacy of RDP are lacking.METHODS: An international, multicenter, retrospective, cohort study, including consecutive patients undergoing RDP and LDP for resectable pancreatic cancer in 33 experienced centers from 11 countries (2010-2019). The primary outcome was R0-resection. Secondary outcomes included lymph node yield, major complications, conversion rate, and overall survival.RESULTS: In total, 542 patients after minimally invasive distal pancreatectomy were included: 103 RDP (19%) and 439 LDP (81%). The R0-resection rate was comparable (75.7% RDP vs. 69.3% LDP, p = 0.404). RDP was associated with longer operative time (290 vs. 240 min, p < 0.001), more vascular resections (7.6% vs. 2.7%, p = 0.030), lower conversion rate (4.9% vs. 17.3%, p = 0.001), more major complications (26.2% vs. 16.3%, p = 0.019), improved lymph node yield (18 vs. 16, p = 0.021), and longer hospital stay (10 vs. 8 days, p = 0.001). The 90-day mortality (1.9% vs. 0.7%, p = 0.268) and overall survival (median 28 vs. 31 months, p = 0.599) did not differ significantly between RDP and LDP, respectively.CONCLUSIONS: In selected patients with resectable pancreatic cancer, RDP and LDP provide a comparable R0-resection rate and overall survival in experienced centers. Although the lymph node yield and conversion rate appeared favorable after RDP, LDP was associated with shorter operating time, less major complications, and shorter hospital stay. The specific benefits associated with each approach should be confirmed by multicenter, randomized trials.

Published
2023

45. Benchmarking of robotic and laparoscopic spleen-preserving distal pancreatectomy by using two different methods

Author

van Ramshorst, Tess M E, Giani, Alessandro, Mazzola, Michele, Dokmak, Safi, Ftériche, Fadhel Samir, Esposito, Alessandro, de Pastena, Matteo, Lof, Sanne, Edwin, Bjørn, Sahakyan, Mushegh, Boggi, Ugo, Kauffman, Emanuele Federico, Fabre, Jean Michel, Souche, Regis Francois, Zerbi, Alessandro, Butturini, Giovanni, Molenaar, Quintus, Al-Sarireh, Bilal, Marino, Marco V, Keck, Tobias, White, Steven A, Casadei, Riccardo, Burdio, Fernando, Björnsson, Bergthor, Soonawalla, Zahir, Koerkamp, Bas Groot, Fusai, Giuseppe Kito, Pessaux, Patrick, Jah, Asif, Pietrabissa, Andrea, Hackert, Thilo, D'Hondt, Mathieu, Pando, Elizabeth, Besselink, Marc G, Ferrari, Giovanni, Hilal, Mohammad Abu, van Ramshorst, Tess M E, Giani, Alessandro, Mazzola, Michele, Dokmak, Safi, Ftériche, Fadhel Samir, Esposito, Alessandro, de Pastena, Matteo, Lof, Sanne, Edwin, Bjørn, Sahakyan, Mushegh, Boggi, Ugo, Kauffman, Emanuele Federico, Fabre, Jean Michel, Souche, Regis Francois, Zerbi, Alessandro, Butturini, Giovanni, Molenaar, Quintus, Al-Sarireh, Bilal, Marino, Marco V, Keck, Tobias, White, Steven A, Casadei, Riccardo, Burdio, Fernando, Björnsson, Bergthor, Soonawalla, Zahir, Koerkamp, Bas Groot, Fusai, Giuseppe Kito, Pessaux, Patrick, Jah, Asif, Pietrabissa, Andrea, Hackert, Thilo, D'Hondt, Mathieu, Pando, Elizabeth, Besselink, Marc G, Ferrari, Giovanni, and Hilal, Mohammad Abu

Abstract

BACKGROUND: Benchmarking is an important tool for quality comparison and improvement. However, no benchmark values are available for minimally invasive spleen-preserving distal pancreatectomy, either laparoscopically or robotically assisted. The aim of this study was to establish benchmarks for these techniques using two different methods.METHODS: Data from patients undergoing laparoscopically or robotically assisted spleen-preserving distal pancreatectomy were extracted from a multicentre database (2006-2019). Benchmarks for 10 outcomes were calculated using the Achievable Benchmark of Care (ABC) and best-patient-in-best-centre methods.RESULTS: Overall, 951 laparoscopically assisted (77.3 per cent) and 279 robotically assisted (22.7 per cent) procedures were included. Using the ABC method, the benchmarks for laparoscopically assisted and robotically assisted spleen-preserving distal pancreatectomy respectively were: 150 and 207 min for duration of operation, 55 and 100 ml for blood loss, 3.5 and 1.7 per cent for conversion, 0 and 1.7 per cent for failure to preserve the spleen, 27.3 and 34.0 per cent for overall morbidity, 5.1 and 3.3 per cent for major morbidity, 3.6 and 7.1 per cent for pancreatic fistula grade B/C, 5 and 6 days for duration of hospital stay, 2.9 and 5.4 per cent for readmissions, and 0 and 0 per cent for 90-day mortality. Best-patient-in-best-centre methodology revealed milder benchmark cut-offs for laparoscopically and robotically assisted procedures, with operating times of 254 and 262.5 min, blood loss of 150 and 195 ml, conversion rates of 5.8 and 8.2 per cent, rates of failure to salvage spleen of 29.9 and 27.3 per cent, overall morbidity rates of 62.7 and 55.7 per cent, major morbidity rates of 20.4 and 14 per cent, POPF B/C rates of 23.8 and 24.2 per cent, duration of hospital stay of 8 and 8 days, readmission rates of 20 and 15.1 per cent, and 90-day mortality rates of 0 and 0 per cent respectively.CONCLUSION: Two

Published
2023

46. Learning Curves of Minimally Invasive Distal Pancreatectomy in Experienced Pancreatic Centers

Author

MS CGO, Cancer, Lof, Sanne, Claassen, Linda, Hannink, Gerjon, Al-Sarireh, Bilal, Björnsson, Bergthor, Boggi, Ugo, Burdio, Fernando, Butturini, Giovanni, Capretti, Giovanni, Casadei, Riccardo, Dokmak, Safi, Edwin, Bjørn, Esposito, Alessandro, Fabre, Jean M., Ferrari, Giovanni, Fretland, Asmund A., Ftériche, Fadhel S., Fusai, Giuseppe K., Giardino, Alessandro, Groot Koerkamp, Bas, D'Hondt, Mathieu, Jah, Asif, Kamarajah, Sivesh K., Kauffmann, Emanuele F., Keck, Tobias, Van Laarhoven, Stijn, Manzoni, Alberto, Marino, Marco V., Marudanayagam, Ravi, Molenaar, Izaak Q., Pessaux, Patrick, Rosso, Edoardo, Salvia, Roberto, Soonawalla, Zahir, Souche, Regis, White, Steven, Van Workum, Frans, Zerbi, Alessandro, Rosman, Camiel, Stommel, Martijn W.J., Abu Hilal, Mohammed, Besselink, Marc G., MS CGO, Cancer, Lof, Sanne, Claassen, Linda, Hannink, Gerjon, Al-Sarireh, Bilal, Björnsson, Bergthor, Boggi, Ugo, Burdio, Fernando, Butturini, Giovanni, Capretti, Giovanni, Casadei, Riccardo, Dokmak, Safi, Edwin, Bjørn, Esposito, Alessandro, Fabre, Jean M., Ferrari, Giovanni, Fretland, Asmund A., Ftériche, Fadhel S., Fusai, Giuseppe K., Giardino, Alessandro, Groot Koerkamp, Bas, D'Hondt, Mathieu, Jah, Asif, Kamarajah, Sivesh K., Kauffmann, Emanuele F., Keck, Tobias, Van Laarhoven, Stijn, Manzoni, Alberto, Marino, Marco V., Marudanayagam, Ravi, Molenaar, Izaak Q., Pessaux, Patrick, Rosso, Edoardo, Salvia, Roberto, Soonawalla, Zahir, Souche, Regis, White, Steven, Van Workum, Frans, Zerbi, Alessandro, Rosman, Camiel, Stommel, Martijn W.J., Abu Hilal, Mohammed, and Besselink, Marc G.

Published
2023

48. Robot-Assisted Versus Laparoscopic Distal Pancreatectomy in Patients with Resectable Pancreatic Cancer: An International, Retrospective, Cohort Study

Author

Chen, Jeffrey W, Van Ramshorst, Tess ME, Lof, Sanne, Al-Sarireh, Bilal, Bjornsson, Bergthor, Boggi, Ugo, Burdio, Fernando, Butturini, Giovanni, Casadei, Riccardo, Coratti, Andrea, D'Hondt, Mathieu, Dokmak, Safi, Edwin, Bjørn, Esposito, Alessandro, Fabre, Jean M, Ferrari, Giovanni, Ftériche, Fadhel S, Fusai, Giuseppe K, Groot Koerkamp, Bas, Hackert, Thilo, Jah, Asif, Jang, Jin-Young, Kauffmann, Emanuele F, Keck, Tobias, Manzoni, Alberto, Marino, Marco V, Molenaar, Quintus, Pando, Elizabeth, Pessaux, Patrick, Pietrabissa, Andrea, Soonawalla, Zahir, Sutcliffe, Robert P, Timmermann, Lea, White, Steven, Yip, Vincent S, Zerbi, Alessandro, Abu Hilal, Mohammad, Besselink, Marc G, European Consortium On Minimally Invasive Pancreatic Surgery (E-MIPS), and Apollo - University of Cambridge Repository

Subjects
Cohort Studies, Pancreatic Neoplasms, Pancreatectomy, Treatment Outcome, Robotic Surgical Procedures, Operative Time, Humans, Laparoscopy, Robotics, Length of Stay, Retrospective Studies
Abstract

BACKGROUND: Robot-assisted distal pancreatectomy (RDP) is increasingly used as an alternative to laparoscopic distal pancreatectomy (LDP) in patients with resectable pancreatic cancer but comparative multicenter studies confirming the safety and efficacy of RDP are lacking. METHODS: An international, multicenter, retrospective, cohort study, including consecutive patients undergoing RDP and LDP for resectable pancreatic cancer in 33 experienced centers from 11 countries (2010-2019). The primary outcome was R0-resection. Secondary outcomes included lymph node yield, major complications, conversion rate, and overall survival. RESULTS: In total, 542 patients after minimally invasive distal pancreatectomy were included: 103 RDP (19%) and 439 LDP (81%). The R0-resection rate was comparable (75.7% RDP vs. 69.3% LDP, p = 0.404). RDP was associated with longer operative time (290 vs. 240 min, p < 0.001), more vascular resections (7.6% vs. 2.7%, p = 0.030), lower conversion rate (4.9% vs. 17.3%, p = 0.001), more major complications (26.2% vs. 16.3%, p = 0.019), improved lymph node yield (18 vs. 16, p = 0.021), and longer hospital stay (10 vs. 8 days, p = 0.001). The 90-day mortality (1.9% vs. 0.7%, p = 0.268) and overall survival (median 28 vs. 31 months, p = 0.599) did not differ significantly between RDP and LDP, respectively. CONCLUSIONS: In selected patients with resectable pancreatic cancer, RDP and LDP provide a comparable R0-resection rate and overall survival in experienced centers. Although the lymph node yield and conversion rate appeared favorable after RDP, LDP was associated with shorter operating time, less major complications, and shorter hospital stay. The specific benefits associated with each approach should be confirmed by multicenter, randomized trials.

Published
2023

50. Cost-Effectiveness of Robotic vs. Laparoscopic Surgery for Different Surgical Procedures: Protocol for a Prospective, Multicentric Study (ROBOCOSTES)

Author

Ielpo, Benedetto, Podda, Mauro, Burdio, Fernando, Sanchez-Velazquez, Patricia, Guerrero, Maria-Alejandra, Nuñez, Javier, Toledano, Miguel, Morales-Conde, Salvador, Mayol, Julio, Lopez-Cano, Manuel, Espín-Basany, Eloy, Pellino, Gianluca, ROBOCOSTES Study Collaborators, Ielpo, Benedetto, Podda, Mauro, Burdio, Fernando, Sanchez-Velazquez, Patricia, Guerrero, Maria-Alejandra, Nuñez, Javier, Toledano, Miguel, Morales-Conde, Salvador, Mayol, Julio, Lopez-Cano, Manuel, Espín-Basany, Eloy, Pellino, Gianluca, Institut Català de la Salut, [Ielpo B, Burdio F, Sanchez-Velazquez P, Guerrero MA] Hepato-Biliary and Pancreatic Surgery Unit, Department of Surgery, Hospital del Mar, Barcelona, Spain. [Podda M] Department of Surgical Science, Emergency Surgery Unit, University of Cagliari, Cagliari, Italy. [Nuñez J] IVEC (Instituto de Validación de la Eficiencia Clínica), Fundación de Investigación HM Hospitales, Madrid, Spain. [Lopez-Cano M] Unitat de Cirurgia de la Paret Abdominal, Vall d'Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Espín-Basany E] Unitat de Cirurgia de Còlon i Recte, Vall d'Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Pellino G] Unitat de Cirurgia de Còlon i Recte, Vall d'Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania 'Luigi Vanvitelli', Naples, Italy, and Vall d'Hebron Barcelona Hospital Campus

Subjects
intervenciones quirúrgicas::procedimientos quirúrgicos mínimamente invasivos::endoscopia::laparoscopia [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], cost-effectivene, ROBOCOSTES study protocol robotic surgery, Cirurgia laparoscòpica, Cirurgia assistida per ordinador, laparoscopic surgery, intervenciones quirúrgicas::cirugía asistida por ordenador::procedimientos quirúrgicos robotizados [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], Epidemiology and Biostatistics::Epidemiology::Uses of Epidemiology::Cost-Effectiveness Evaluation [PUBLIC HEALTH], Surgical Procedures, Operative::Minimally Invasive Surgical Procedures::Endoscopy::Laparoscopy [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], multicenter studies, QALY, epidemiología y bioestadística::epidemiología::usos de la epidemiología::evaluación de coste-efectividad [SALUD PÚBLICA], Cost-eficàcia, Cost-effectiveness, Surgery, cost-effectiveness, Surgical Procedures, Operative::Surgery, Computer-Assisted::Robotic Surgical Procedures [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT]
Abstract

Cost-effectiveness; Laparoscopic surgery; Multicenter studies Rendibilitat; Cirurgia laparoscòpica; Estudis multicèntrics Rentabilidad; Cirugía laparoscópica; Estudios multicéntricos Background: The studies which address the impact of costs of robotic vs. laparoscopic approach on quality of life (cost-effectiveness studies) are scares in general surgery. Methods: The Spanish national study on cost-effectiveness differences among robotic and laparoscopic surgery (ROBOCOSTES) is designed as a prospective, multicentre, national, observational study. The aim is to determine in which procedures robotic surgery is more cost-effective than laparoscopic surgery. Several surgical operations and patient populations will be evaluated (distal pancreatectomy, gastrectomy, sleeve gastrectomy, inguinal hernioplasty, rectal resection for cancer, Heller cardiomiotomy and Nissen procedure). Discussion: The results of this study will demonstrate which treatment (laparoscopic or robotic) and in which population is more cost-effective. This study will also assess the impact of previous surgical experience on main outcomes. Project PI20/00008, funded by Instituto de Salud Carlos III (ISCIII) and co-funded by the European Union.

Published
2022
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