34 results on '"Buras M"'
Search Results
2. 661 Effect of sun exposure on distribution of nevi and melanoma in Caucasian and skin of color individuals
- Author
-
Harvey, J., primary, Besch-Stokes, J., additional, Bhullar, P., additional, Boudreaux, B., additional, Puri, P., additional, Severson, K., additional, Buras, M., additional, Costello, C., additional, Pittelkow, M.R., additional, and Mangold, A.R., additional
- Published
- 2022
- Full Text
- View/download PDF
3. Heavy Flavours Ii
- Author
-
A J Buras, M Lindner and A J Buras, M Lindner
- Published
- 1998
4. Engaging the Opioid Epidemic Head on: Improving Proper Disposal of Unused Opioid Medications after Surgery
- Author
-
Haverland, R., primary, Luckritz, T., additional, Lim, E., additional, Buras, M., additional, and Yi, J., additional
- Published
- 2020
- Full Text
- View/download PDF
5. Heavy Flavours
- Author
-
A J Buras, M Lindner and A J Buras, M Lindner
- Published
- 1992
6. 393 Survival and glycemic control in patients with squamous cell carcinoma
- Author
-
Ederaine, S.A., primary, Dominguez, J., additional, Harvey, J., additional, Mangold, A., additional, Cook, C., additional, Kosiorek, H., additional, Buras, M., additional, Coppola, K., additional, Verona, P., additional, and Karlin, N., additional
- Published
- 2020
- Full Text
- View/download PDF
7. Mortality Rates in Laparoscopic and Robotic Benign Gynecologic Surgery- A Systemic Review and Meta-Analysis
- Author
-
Behbehani, S, primary, Suarez, ME, additional, Buras, M, additional, Magtibay, PM, additional, and Magrina, JF, additional
- Published
- 2019
- Full Text
- View/download PDF
8. Pregnancy Rates After Surgical Resection of Deep Infiltrating Endometriosis - A Systematic Review and Meta-Analysis
- Author
-
Behbehani, S, primary, Suarez, ME, additional, Buras, M, additional, Yi, J, additional, and Magrina, JF, additional
- Published
- 2019
- Full Text
- View/download PDF
9. 03:00 PM Abstract No. 248 Treatment of liver transplant hepatic artery stenosis: drug-eluting vs. bare-metal stents
- Author
-
Fleck, D., primary, Naidu, S., additional, Alzubaidi, S., additional, Kriegshauser, J., additional, Knuttinen, G., additional, Sweeney, J., additional, Oklu, R., additional, Buras, M., additional, and Golafshar, M., additional
- Published
- 2019
- Full Text
- View/download PDF
10. 320 Paraneoplastic granuloma annulare in association with solid organ malignancies
- Author
-
Liang, H., primary, Costello, C., additional, Xie, D., additional, Buras, M., additional, Nelson, S., additional, Sekulic, A., additional, Pittelkow, M., additional, and Mangold, A., additional
- Published
- 2018
- Full Text
- View/download PDF
11. 1253 Distribution of acral melanocytic nevi and acral melanomas on the plantar foot
- Author
-
Ghanavatian, S., primary, Costello, C., additional, Buras, M., additional, Liang, H., additional, Swanson, D., additional, and Mangold, A., additional
- Published
- 2018
- Full Text
- View/download PDF
12. Educational and practice gaps in the management of volar melanocytic lesions.
- Author
-
Costello, C. M., Ghanavatian, S., Temkit, M., Buras, M. R., DiCaudo, D. J., Swanson, D. L., and Mangold, A. R.
- Subjects
MELANOMA ,BIOPSY ,DERMATOLOGY ,MELANOCYTES ,DERMATOLOGISTS - Abstract
Abstract: Background: The benign and malignant patterns of acral melanocytic naevi (AMN) and acral melanomas (AM) have been defined in a series of retrospective studies. A three‐step algorithm was developed to determine when to biopsy acral melanocytic lesions. This algorithm has only been applied to a Japanese population. Objectives: Our study aimed to review the current management strategy of acral melanocytic lesions and to investigate the utility of the three‐step algorithm in a predominately Caucasian cohort. Methods: A retrospective search of the pathology and image databases at Mayo Clinic was performed between the years 2006 and 2016. Only cases located on a volar surface with dermoscopic images were included. Two dermatologists reviewed all dermoscopic images and assigned a global dermoscopic pattern. Clinical and follow‐up data were gathered by chart review. All lesions with known diameter and pathological diagnosis were used for the three‐step algorithm. Results: Regular fibrillar and ridge patterns were more likely to be biopsied (P = 0.01). The majority of AMN (58.1%) and AM (60%) biopsied were due to physician‐deemed concerning dermoscopic patterns. 39.2% of these cases were parallel furrow, lattice‐like or regular fibrillar. When patients were asked to follow‐up within a 3‐ to 6‐month period, only 16.7% of the patients returned within that interval. The three‐step algorithm would have correctly identified four of five AM for biopsy, missing a 6 mm, multicomponent, invasive melanoma. Conclusion: We found one major educational gap in the recognition of low‐risk lesions with high rates of biopsy of the fibrillary pattern. Recognizing low‐risk dermoscopic patterns could reduce the rate of biopsy of AMN by 23.3%. We identified two major practice gaps, poor patient compliance with follow‐up and the potential insensitivity of the three‐step algorithm to small multicomponent acral melanocytic lesions. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
13. Evaluation of Clinical Factors Associated with Adverse Drug Events in Patients Receiving Sub-Anesthetic Ketamine Infusions
- Author
-
Stoker AD, Rosenfeld DM, Buras MR, Alvord JM, and Gorlin AW
- Subjects
ketamine ,pain ,depression ,adverse ,drug-event ,Medicine (General) ,R5-920 - Abstract
Alexander D Stoker,1 David M Rosenfeld,1 Matthew R Buras,2 Jeremy M Alvord,1 Andrew W Gorlin1 1Department of Anesthesiology and Perioperative Medicine, Mayo Clinic Arizona, Phoenix, AZ, USA; 2Mayo Clinic Arizona, Phoenix, AZ, USACorrespondence: Alexander D StokerDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic Arizona, 5777 E Mayo Blvd, Phoenix, AZ 85054, USATel +1 480-510-7933Email Stoker.Alexander@mayo.eduIntroduction: Sub-anesthetic ketamine is frequently used as an analgesic to reduce perioperative opioid consumption and has also been shown to have antidepressant effects. Side effects of ketamine include dizziness, diplopia, nystagmus, and psychomimetic effects. It is unclear what clinical factors may be associated with ketamine-related adverse drug events (ADEs).Methods: We performed a retrospective review of 95 patients who received sub-anesthetic ketamine infusions at our institution. Data examined associations between ketamine-related ADEs and various clinical characteristics including chronic pain, depression, or psychiatric disorder, patient physical characteristics, chronic opioid use, perioperative opioid use, dose and duration of ketamine infusions, pain scores, and perioperative medications such as serotonergic agents, central nervous system (CNS) depressants, and analgesics.Results: Overall incidence of ketamine-related ADEs was 29.5% and the incidence of psychomimetic effects was 14.8%. We observed that patients with a history of depression have a lower incidence of ketamine-related ADEs compared to patients without a history of depression (10.3% vs 37.3%; p value = 0.007).Conclusion: Patients with depression were found to have a statistically significant reduction in the incidence of ketamine-related ADEs. We found no statistically significant positive associations between ketamine-related ADEs and other clinical factors such as a history of chronic pain, psychiatric disease, patient physical characteristics, perioperative opioid use, dose of ketamine infusion, or co-administration of other CNS depressants.Keywords: ketamine, pain, depression, adverse, drug-event
- Published
- 2019
14. Modyfication of photocatalytic properties of titanium dioxide by mechanochemical method
- Author
-
Dulian Piotr, Buras Marlena, and Żukowski Witold
- Subjects
mechanochemistry ,high-energy ball milling ,titanium dioxide ,photocatalysis ,Chemistry ,QD1-999 - Abstract
The paper presents a simple way to improve the photocatalytic properties of titanium dioxide using mechanochemical method. The TiO2 (Anatase) powders was subjected to high-energy ball milling in dry environment and in methanol. It has been shown that it is possible to induce the phase transformation from Anatase to Rutile and produce a material with a higher photocatalytic activity in the UV light. Physicochemical characteristics of the products were based on the following methods and techniques: X-ray powder diffraction (XRD), IR and UV-Vis (DR) spectroscopy, measurements of specific surface area (BET). The photocatalytic activity of the powders was measured in the decomposition reaction of methyl orange in water.
- Published
- 2016
- Full Text
- View/download PDF
15. Lower muscle protein synthesis in humans with obesity concurrent with lower expression of muscle IGF1 splice variants.
- Author
-
Freitas EDS, Kras KA, Roust LR, De Filippis EA, Kimball SR, Buras M, and Katsanos CS
- Subjects
- Humans, Receptor, IGF Type 1 genetics, Receptor, IGF Type 1 metabolism, Muscle, Skeletal metabolism, Obesity genetics, Obesity metabolism, RNA, Messenger genetics, RNA, Messenger metabolism, Mitochondrial Proteins metabolism, Muscle Proteins, Insulin-Like Growth Factor I genetics, Insulin-Like Growth Factor I metabolism
- Abstract
Objective: This study tested the hypothesis that expression of insulin-like growth factor 1 (IGF-1) protein and mRNA splice variants is lower in skeletal muscle of humans with obesity who have a lower mixed-muscle protein fractional synthesis rate (MMP-FSR) when compared with individuals without obesity., Methods: The study included nine participants with obesity (OB, mean [SD], BMI = 35 [3] kg/m
2 , MMP-FSR = 0.06%/h [0.02%/h]) and nine participants without obesity (W-OB, BMI = 24 [3] kg/m2 , MMP-FSR = 0.08%/h [0.02%/h]; for both BMI and MMP-FSR p < 0.05). MMP-FSR and mitochondrial protein FSR were measured following an overnight fast., Results: Along with lower MMP-FSR, OB participants displayed lower mitochondrial protein FSR (p = 0.03) compared with W-OB participants. Expression of IGF-1 (p = 0.04) and IGF-1 receptor (p < 0.01) proteins was lower in muscle of OB participants. In addition, OB participants had lower (p < 0.05) mRNA expression of IGF1 variants Eb and Ec. This study demonstrates that lower protein synthesis in muscle of humans with obesity occurs concurrently with lower expression of muscle IGF-1 and IGF-1 receptor proteins, as well as lower mRNA expression of the IGF1 splice variants., Conclusions: These findings indicate that lower protein synthesis observed in muscle of humans with obesity may result from diminished muscle IGF1 gene expression., (© 2023 The Obesity Society.)- Published
- 2023
- Full Text
- View/download PDF
16. Study of association between antibodies to non-HLA kidney self-antigens and progression to chronic immune injury after kidney transplantation.
- Author
-
Nair S, Ravichandran R, Heilman R, Jaramillo A, Buras M, Kaplan B, Itabashi Y, Ramon D, Hacke K, Smith B, and Mohanakumar T
- Subjects
- Humans, Autoantigens, Retrospective Studies, Graft Rejection, Kidney, Antibodies, HLA Antigens, Graft Survival, Kidney Transplantation
- Abstract
Background: Immune response to several kidney self-antigens (KSAg) such as Collagen IV (Col-IV), Perlecan (PL), and Fibronectin (FN) have been associated with antibody-mediated damage and poor allograft survival. Thus, the aim of this study was to determine if humoral immune responses to KSAg correlates with progression of chronic immune injury (CII) changes at 1 year or 2 years., Methods: Kidney transplant recipients who underwent 1- or 2-year biopsies, with chronic interstitial inflammation (ci > 1) and/or glomerular membrane double contouring (cg > 0) were analyzed with matched controls. Sera were analyzed retrospectively for antibodies against KSAg using ELISA. The presence of antibodies to KSAg were compared at 0, 4, 12, and 24 months using logistic regression., Results: We identified a cohort of 214 kidney transplant recipients. Of these, we identified 33 cases and matched 66 controls. Logistical regression showed an odds ratio of 1 with the confidence interval crossing 1 for the presence of response to KSAg at all the time points., Conclusions: Humoral immune responses to either KSAg alone or in combination with donor-specific anti-HLA antibodies are not associated with progression to CII at 1 and 2 years after kidney transplantation., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023. Published by Elsevier Inc.)
- Published
- 2023
- Full Text
- View/download PDF
17. Human Trafficking Education: A Pilot Study of Integration into Medical School Curriculum.
- Author
-
Das DM, Talbott JM, Dutcher JS, Buras M, Lim E, Vegunta S, David P, and Kling JM
- Abstract
Objectives: Few medical schools incorporate formal education on human trafficking (HT) and sex trafficking (ST) into their curriculum. Our objective was to develop, implement, and evaluate education on HT and ST in the first-year medical student curriculum., Methods: The curriculum included a standardized patient (SP) experience and lecture. As part of their mandatory sexual health course, students interviewed an SP who presented with red flags for ST and then participated in a discussion led by a physician-facilitator in an observed small group setting. A multiple-choice survey to assess knowledge about HT and ST was developed and administered to students before and after the SP interview., Results: Of the 50 first-year medical students, 29 (58%) participated in the survey. Compared with the students' baseline scores (according to the percentage of correct responses), scores after the educational intervention showed a significant increase in percentage correct on questions related to trafficking definition and scope (elder care, P = .01; landscaping, P = .03); victim identification ( P < .001); referral to services ( P < .001); legal issues ( P = .01); and security ( P < .001). On the basis of the feedback, a 2-hour lecture, which was adapted from the American Medical Women's Association-Physicians Against the Trafficking of Humans "Learn to Identify and Fight Trafficking" training, was presented the next year to all first-year medical students as part of their longitudinal clinical skills course and before the SP case. Curriculum objectives included learning trafficking definitions, victim/survivor identification, intersections with health care, the local impact of HT, and available resources., Conclusion: This curriculum fulfills course objectives and could be replicated at other institutions. Further evaluation of this pilot curriculum is necessary to evaluate its effectiveness., Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2023.)
- Published
- 2023
- Full Text
- View/download PDF
18. Skin Cancer Knowledge, Attitudes and Sun Protection Practices in the Hispanic Population: A Cross-Sectional Survey.
- Author
-
Besch-Stokes J, Brumfiel CM, Patel MH, Harvey J, Montoya J, Severson KJ, Cumsky H, Buras M, Fagoaga JEG, Costello CM, Pittelkow MR, and Mangold AR
- Subjects
- Humans, Cross-Sectional Studies, Health Knowledge, Attitudes, Practice, Hispanic or Latino, Health Behavior, Skin Neoplasms prevention & control
- Abstract
Hispanics are more likely to be diagnosed with skin cancer at a later stage and experience worse overall survival than Whites. The objective of this cross-sectional study was to assess the skin cancer knowledge, attitudes, perceived risk, and sun protection practices among an underserved population in the Phoenix area. We recruited participants from the greater Phoenix area to undergo skin examination and complete a questionnaire. 208 participants were included. The majority were Hispanic (64.9%). Of this Hispanic group, most were from Mexico (87.9%). The Hispanic cohort had an overall mean skin cancer knowledge score of 3.68/6, the lowest of any other racial/ethnic group, but had the highest desire to learn more about skin cancer (64.6%, "strongly agree"). They were the most concerned about developing skin cancer (50.4%, "very concerned") but had relatively lower rates of sun protection practices (7.9% "always use" sunscreen, 22.0% "always use" sun-protective clothing). Limitations of this study include a small sample size, lack of validation for the skin cancer knowledge score, lack of season as a covariate in the multivariate analysis, lack of follow-up, and lack of robust skin cancer risk assessment. In conclusion, despite poorer skin cancer knowledge and sun protection practices, the Hispanic population had the highest concern for developing skin cancer and desire to learn more about skin cancer. Targeted and culturally relevant skin cancer and sun protection education for this group is needed., (© 2022. W. Montague Cobb-NMA Health Institute.)
- Published
- 2023
- Full Text
- View/download PDF
19. Effect of COVID-19 on the incidence of postintubation laryngeal lesions.
- Author
-
Buras M, DeSisto N, and Holdgraf R
- Abstract
Background: Critically ill patients intubated in the intensive care unit experience prolonged intubation leading to increased frequency of laryngeal injuries. This study aimed to demonstrate a suspected increase in vocal fold injury in patients who were intubated with COVID-19 as compared with patients intubated for other reasons., Methods: A retrospective review of medical records was performed to identify patients examined using flexible endoscopic evaluation of swallowing exams. The study included 25 patients with COVID-19 and 27 without COVID-19 at Baylor Scott & White Medical Center in Temple, Texas. Various injuries were evaluated, ranging from granulation tissue to vocal cord paralysis. Severe lesions were those causing clinically significant airway obstruction or requiring operative intervention. The incidence of laryngeal injury in patients intubated for COVID-19 was then compared with that of patients intubated for other reasons., Results: The increased presence of severe injury in COVID-positive patients appeared clinically significant but was not statistically significant ( P = 0.06). Interestingly, patients who received pronation therapy had 4.6 times the odds of more severe injury compared with patients who did not ( P = 0.009)., Conclusion: Lower thresholds for performing flexible laryngoscopy on postintubated patients who are proned may allow for earlier intervention and reduce morbidity in an already at-risk population., Competing Interests: The authors report no funding or conflicts of interest., (Copyright © 2023 Baylor University Medical Center.)
- Published
- 2023
- Full Text
- View/download PDF
20. Breakthrough COVID-19 infection inducing acute epiglottitis in an immunized host.
- Author
-
Mitchell M, Buras M, Shutter M, and Wieters JS
- Abstract
We present the case of a 32-year-old man vaccinated with the Johnson & Johnson coronavirus disease 2019 (COVID-19) vaccine who presented with pharyngodynia and breakthrough COVID-19 infection. The patient was diagnosed with severe acute respiratory syndrome coronavirus 2 infection via nasal swab and acute epiglottitis by imaging and flexible laryngoscopy. While COVID-19 is known to present with pharyngodynia, nasal congestion, rhinorrhea, and olfactory dysfunction, epiglottitis is not a typical presentation. Fewer than 10 cases of acute epiglottitis in the setting of COVID-19 have been reported. Independently, active COVID-19 infections can result in acute respiratory distress syndrome, while epiglottitis may lead to complete airway obstruction. The combination of these two conditions may lead to challenging clinical management., (Copyright © 2022 Baylor University Medical Center.)
- Published
- 2022
- Full Text
- View/download PDF
21. Lack of Increase in Muscle Mitochondrial Protein Synthesis During the Course of Aerobic Exercise and Its Recovery in the Fasting State Irrespective of Obesity.
- Author
-
Serrano N, Tran L, Hoffman N, Roust L, De Filippis EA, Carroll CC, Patel SH, Kras KA, Buras M, and Katsanos CS
- Abstract
Acute aerobic exercise induces skeletal muscle mitochondrial gene expression, which in turn can increase muscle mitochondrial protein synthesis. In this regard, the peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), is a master regulator of mitochondrial biogenesis, and thus mitochondrial protein synthesis. However, PGC-1α expression is impaired in muscle of humans with obesity in response to acute aerobic exercise. Therefore, we sought to determine whether muscle mitochondrial protein synthesis is also impaired under the same conditions in humans with obesity. To this end, we measured mitochondrial and mixed-muscle protein synthesis in skeletal muscle of untrained subjects with (body fat: 34.7 ± 2.3%) and without (body fat: 25.3 ± 3.3%) obesity in a basal period and during a continuous period that included a 45 min cycling exercise (performed at an intensity corresponding to 65% of heart rate reserve) and a 3-h post-exercise recovery. Exercise increased PGC-1α mRNA expression in muscle of subjects without obesity, but not in subjects with obesity. However, muscle mitochondrial protein synthesis did not increase in either subject group. Similarly, mixed-muscle protein synthesis did not increase in either group. Concentrations of plasma amino acids decreased post-exercise in the subjects without obesity, but not in the subjects with obesity. We conclude that neither mitochondrial nor mixed-muscle protein synthesis increase in muscle of humans during the course of a session of aerobic exercise and its recovery period in the fasting state irrespective of obesity. Trial Registration: The study has been registered within ClinicalTrials.gov (NCT01824173)., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Serrano, Tran, Hoffman, Roust, De Filippis, Carroll, Patel, Kras, Buras and Katsanos.)
- Published
- 2021
- Full Text
- View/download PDF
22. Artificial Intelligence Trumps TAVI 2 -SCORE and CoreValve Score in Predicting 1-Year Mortality Post-Transcatheter Aortic Valve Replacement.
- Author
-
Agasthi P, Ashraf H, Pujari SH, Girardo ME, Tseng A, Mookadam F, Venepally NR, Buras M, Khetarpal BK, Allam M, Eleid MF, Greason KL, Beohar N, Siegel RJ, Sweeney J, Fortuin FD, Holmes DR Jr, and Arsanjani R
- Subjects
- Aged, Aged, 80 and over, Aortic Valve diagnostic imaging, Aortic Valve surgery, Artificial Intelligence, Female, Humans, Male, Retrospective Studies, Risk Factors, Treatment Outcome, Aortic Valve Stenosis diagnostic imaging, Aortic Valve Stenosis surgery, Heart Valve Prosthesis, Transcatheter Aortic Valve Replacement adverse effects
- Abstract
Background/purpose: Machine learning has been used to predict procedural risk in patients undergoing various medical interventions and procedures. One-year mortality in patients after Transcatheter Aortic Valve Replacement (TAVR) has a wide range (from 8.5 to 24% in various studies). We sought to apply machine learning to determine predictors of one year mortality in patients undergoing TAVR., Methods/materials: A retrospective study of 1055 patients who underwent TAVR (Jan 2014-June 2017) with one-year follow up was completed. Baseline demographics, clinical, electrocardiography (ECG), Computed Tomography (CT) and echocardiography data were abstracted. Variables with near zero variance or ≥50% missing data were excluded. The Gradient Boosting Machine learning (GBM) prediction model included 163 variables and was optimized using 5-fold cross-validation repeated 10-times. The receiver operator characteristic (ROC) for the GBM model was calculated to predict one-year mortality post TAVR, and then compared to the TAVI
2 -SCORE and CoreValve score., Results: Among 1055 TAVR patients (mean age 80.9 ± 7.9 years, 42% female), 14.02% died at one year. 78% had balloon expandable valves placed. Based on GBM, the ten most predictive variables for one-year survival were cardiac power index, hemoglobin, systolic blood pressure, INR, diastolic blood pressure, body mass index, valve calcium score, serum creatinine, aortic annulus area, and albumin. The area under ROC to predict survival for the GBM model vs TAVI2 -SCORE and CoreValve Score was 0.72 (95% CI 0.68-0.78) vs 0.56 (95%CI 0.51-0.62) and 0.53 (95% CI 0.47-0.59) respectively with p < 0.0001., Conclusion: The GBM model outperforms TAVI2 -SCORE and CoreValve Score in predicting mortality one-year post TAVR., Competing Interests: Declaration of competing interest The authors report no financial relationships or conflicts of interest regarding the content herein., (Copyright © 2020 Elsevier Inc. All rights reserved.)- Published
- 2021
- Full Text
- View/download PDF
23. Survival and glycemic control in patients with co-existing squamous cell carcinoma and diabetes mellitus.
- Author
-
Ederaine SA, Dominguez JL, Harvey JA, Mangold AR, Cook CB, Kosiorek H, Buras M, Coppola K, and Karlin NJ
- Abstract
Aim: This study examined the impact of diabetes mellitus (DM) on survival in squamous cell carcinoma (SCC) patients, and the impact of SCC on glycemic control., Materials & Methods: Patients with newly diagnosed SCC with and without DM were matched 1:1 (2007-2017). Overall survival and recurrence-free survival were estimated using the Kaplan-Meier method. Hemoglobin A
1c (HbA1c ) and glucose level during the year following cancer diagnosis were compared using mixed models., Results: HbA1c decreased over time in DM patients (p = 0.04). The 5-year overall survival was 61% in DM patients, compared with 78% in patients without DM (p = 0.004)., Conclusion: The presence of co-existing DM adversely impacted survival in patients with SCC. SCC did not affect glycemic control., Competing Interests: Financial & competing interests disclosure The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. No writing assistance was utilized in the production of this manuscript., (© 2021 Mayo foundation for Medical Education and Research.)- Published
- 2021
- Full Text
- View/download PDF
24. Treatment of Hepatic Artery Stenosis in Liver Transplant Patients Using Drug-Eluting versus Bare-Metal Stents.
- Author
-
Naidu S, Alzubaidi S, Knuttinen G, Patel I, Fleck A, Sweeney J, Aqel B, Larsen B, Buras M, Golafshar M, and Oklu R
- Abstract
Hepatic artery stenosis after liver transplant is often treated with endovascular stent placement. Our institution has adopted use of drug-eluting stents, particularly in small-caliber arteries. We aimed to compare patency rates of drug-eluting stents vs. traditional bare-metal stents. This was a single-institution, retrospective study of liver transplant hepatic artery stenosis treated with stents. Primary patency was defined as time from stent placement to resistive index on Doppler ultrasonography (<0.5), hepatic artery thrombosis, or any intervention including surgery. Fifty-two patients were treated with stents (31 men; mean age, 57 years): 15, drug-eluting stents; 37, bare-metal stents. Mean arterial diameters were 4.1 mm and 5.1 mm, respectively. Technical success was 100% (52/52). At 6 months, 1, 2, and 3 years, primary patency for drug-eluting stents was 80%, 71%, 71%, and 71%; bare-metal stents: 76%, 65%, 53%, and 46% ( p = 0.41). Primary patency for small-caliber arteries (3.5-4.5 mm) with drug-eluting stents was 93%, 75%, 75%, and 75%; bare-metal stents: 60%, 60%, 50%, and 38% ( p = 0.19). Overall survival was 100%, 100%, 94%, and 91%. Graft survival was 100%, 98%, 96%, and 90%. Stenting for hepatic artery stenosis was safe and effective. While not statistically significant, patency improved with drug-eluting stents compared with bare-metal stents, especially in arteries < 4.5 mm in diameter. Drug-eluting stents can be considered for liver transplant hepatic artery stenosis, particularly in small-caliber arteries.
- Published
- 2021
- Full Text
- View/download PDF
25. Pretransplant body mass index on outcomes of allogeneic hematopoietic stem cell transplantation.
- Author
-
Tai J, Buras M, Leis J, Noel P, Palmer J, Slack J, and Sproat L
- Subjects
- Body Mass Index, Retrospective Studies, Transplantation, Homologous, Hematopoietic Stem Cell Transplantation
- Published
- 2020
- Full Text
- View/download PDF
26. Early Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients.
- Author
-
Joyner M, Wright RS, Fairweather D, Senefeld J, Bruno K, Klassen S, Carter R, Klompas A, Wiggins C, Shepherd JR, Rea R, Whelan E, Clayburn A, Spiegel M, Johnson P, Lesser E, Baker S, Larson K, Ripoll Sanz J, Andersen K, Hodge D, Kunze K, Buras M, Vogt M, Herasevich V, Dennis J, Regimbal R, Bauer P, Blair J, van Buskirk C, Winters J, Stubbs J, Paneth N, and Casadevall A
- Abstract
Background: Convalescent plasma is the only antibody based therapy currently available for COVID-19 patients. It has robust historical precedence and sound biological plausibility. Although promising, convalescent plasma has not yet been shown to be safe as a treatment for COVID-19., Methods: Thus, we analyzed key safety metrics after transfusion of ABO-compatible human COVID-19 convalescent plasma in 5,000 hospitalized adults with severe or life threatening COVID-19, with 66% in the intensive care unit, as part of the US FDA Expanded Access Program for COVID-19 convalescent plasma., Results: The incidence of all serious adverse events (SAEs) in the first four hours after transfusion was <1%, including mortality rate (0.3%). Of the 36 reported SAEs, there were 25 reported incidences of related SAEs, including mortality (n=4), transfusion-associated circulatory overload (TACO; n=7), transfusion-related acute lung injury (TRALI; n=11), and severe allergic transfusion reactions (n=3). However, only 2 (of 36) SAEs were judged as definitely related to the convalescent plasma transfusion by the treating physician. The seven-day mortality rate was 14.9%., Conclusion: Given the deadly nature of COVID-19 and the large population of critically-ill patients included in these analyses, the mortality rate does not appear excessive. These early indicators suggest that transfusion of convalescent plasma is safe in hospitalized patients with COVID-19.
- Published
- 2020
- Full Text
- View/download PDF
27. Mortality Rates in Benign Laparoscopic and Robotic Gynecologic Surgery: A Systematic Review and Meta-analysis.
- Author
-
Behbehani S, Suarez-Salvador E, Buras M, Magtibay P, and Magrina J
- Subjects
- Female, Gynecologic Surgical Procedures adverse effects, Gynecologic Surgical Procedures methods, Gynecologic Surgical Procedures statistics & numerical data, Hospital Mortality, Humans, Hysterectomy adverse effects, Hysterectomy methods, Hysterectomy mortality, Hysterectomy statistics & numerical data, Laparoscopy adverse effects, Laparoscopy methods, Laparoscopy statistics & numerical data, Minimally Invasive Surgical Procedures adverse effects, Minimally Invasive Surgical Procedures methods, Minimally Invasive Surgical Procedures mortality, Minimally Invasive Surgical Procedures statistics & numerical data, Mortality, Observational Studies as Topic statistics & numerical data, Postoperative Complications mortality, Randomized Controlled Trials as Topic statistics & numerical data, Robotic Surgical Procedures adverse effects, Robotic Surgical Procedures methods, Robotic Surgical Procedures statistics & numerical data, Gynecologic Surgical Procedures mortality, Laparoscopy mortality, Robotic Surgical Procedures mortality
- Abstract
Objective: To review mortality rates in benign gynecologic minimally invasive laparoscopic and robotic surgery (MIS) and the rates associated with commonly performed MIS procedures., Data Sources: An electronic-based search was performed on PubMed, Embase, Scopus, Web of Science, and Cochrane Database for articles published in the last 10 years in English, French, German, Spanish, and Italian., Methods of Study Selection: All MIS articles in benign gynecology reporting operative mortality (within 30 days) were reviewed., Tabulation, Integration, and Results: The articles identified through the aforementioned search criteria were independently evaluated by the first 2 authors. The Newcastle-Ottawa scale for observational studies and Cochrane risk-of-bias assessment tool for randomized controlled trials were used to assess the risk of bias. Meta-analysis was applied to calculate pooled mortality rates using the inverse-variance method. Twenty-one articles (124 216 patients) were included. Operative mortality from any benign MIS (laparoscopy and robotics) procedure was 1:6456 (95% confidence interval [CI]: 1:3946-1:10 562). Studies were then grouped based on the surgical procedure. The mortality rate for hysterectomy (119 721 patients), sacrocolpopexy, and adnexal surgery and diagnostic laparoscopy was 1:6814 (95% CI: 1:4119-1:11 275), 1:1246 (95% CI: 1:36-1:44 700), and 1:2245 (95% CI: 1:45-1:113 372), respectively. Eighteen articles reported operative mortality for laparoscopic surgery and 4 for robotic surgery., Conclusion: Operative mortality in benign minimally invasive gynecologic surgery is low, and mortality for laparoscopic and robotic approaches appears to be similar., (Copyright © 2019 AAGL. Published by Elsevier Inc. All rights reserved.)
- Published
- 2020
- Full Text
- View/download PDF
28. Same-Day Discharge after Vaginal Hysterectomy with Pelvic Floor Reconstruction: Pilot Study.
- Author
-
Liu L, Yi J, Cornella J, Butterfield R, Buras M, and Wasson M
- Subjects
- Adult, Aged, Aged, 80 and over, Cohort Studies, Female, Gynecologic Surgical Procedures adverse effects, Gynecologic Surgical Procedures methods, Gynecologic Surgical Procedures statistics & numerical data, Hospitalization statistics & numerical data, Humans, Middle Aged, Patient Discharge statistics & numerical data, Pelvic Organ Prolapse epidemiology, Pilot Projects, Postoperative Complications epidemiology, Postoperative Complications etiology, Postoperative Complications therapy, Urinary Incontinence epidemiology, Ambulatory Surgical Procedures adverse effects, Ambulatory Surgical Procedures methods, Ambulatory Surgical Procedures statistics & numerical data, Enhanced Recovery After Surgery, Hysterectomy, Vaginal adverse effects, Hysterectomy, Vaginal methods, Hysterectomy, Vaginal statistics & numerical data, Pelvic Floor surgery, Pelvic Organ Prolapse surgery, Plastic Surgery Procedures adverse effects, Plastic Surgery Procedures methods, Plastic Surgery Procedures statistics & numerical data, Urinary Incontinence surgery
- Abstract
Study Objective: To determine the safety and feasibility of same-day discharge (SDD) in patients undergoing vaginal hysterectomy with pelvic floor reconstruction., Design: Prospective cohort pilot study., Setting: Single academic medical center., Patients: Women undergoing vaginal hysterectomy with pelvic floor reconstruction were considered for inclusion in the study., Interventions: SDD or overnight hospitalization after surgery., Measurements and Main Results: A total cohort of 55 women undergoing vaginal hysterectomy and pelvic floor reconstruction for pelvic organ prolapse and/or urinary incontinence was identified. The control group consisted of 19 women who were planned for overnight hospitalization. The intervention group had 36 women who were planned for SDD. In the intervention group 63.9% of patients (n = 23) were successfully discharged home and 36.1% (n = 13) required an unplanned overnight admission. Reasons for unplanned admission included persistent anesthetic effects (dizziness/nausea/drowsiness, n = 9, 69%), uncontrolled pain (n = 1, 7.7%), fever (n = 1, 7.7%), anemia (n = 2, 15.4%), with return to operating room for hematoma evacuation (n = 1, 7.7%). A voiding trial was passed on the first attempt in 30 patients (54.5%). The percentage of successful voiding trials on the first attempt was 30.8% for patients requiring unplanned admission and 78.9% for patients with planned overnight hospitalization (p = .011). There were no significant differences in the number of emergency department visits (p = .677) or unplanned office visits (p = .193) between the control and intervention groups., Conclusion: SDD after vaginal hysterectomy with pelvic floor reconstruction appears to be safe and feasible. Patients who were discharged the same day did not require a higher volume of emergency department or office evaluations., (Copyright © 2019. Published by Elsevier Inc.)
- Published
- 2020
- Full Text
- View/download PDF
29. Mortality Rates in Laparoscopic and Robotic Gynecologic Oncology Surgery: A Systemic Review and Meta-analysis.
- Author
-
Behbehani S, Suarez-Salvador E, Buras M, Magtibay P, and Magrina J
- Subjects
- Female, Humans, Outcome Assessment, Health Care, Gynecologic Surgical Procedures methods, Gynecologic Surgical Procedures mortality, Laparoscopy mortality, Robotic Surgical Procedures mortality
- Abstract
Objective: To review early operative mortality (<30 days) for minimally invasive surgery (MIS), laparoscopic and robotic, in gynecologic oncology., Data Sources: An electronic-based search was performed in PubMed, Embase, Scopus, Web of Science, and Cochrane Database in the last 10 years., Methods of Study Selection: All MIS studies in gynecologic oncology reporting operative mortality from any cause (within 30 days) were included. Studies were excluded if mortality was not reported for MIS or included benign gynecology., Tabulation, Integration, and Results: Meta-analysis was applied to calculate pooled mortality rates using the inverse-variance method. The relative risks and their corresponding 95% confidence intervals (CIs) were calculated using the Mantel-Haenszel method. Sixty-five studies were included (39 183 patients) for an operative mortality of 1:381 (95% CI, 1:306-1:474). Studies were subselected and analyzed by procedures, malignancy, and surgical approach. Of 39 183 patients, 38 619 underwent any type of hysterectomy for a mortality of 1:379 (95% CI, 1:304-1:472). The mortality was 1:281 (95% CI, 1:169-1:469) for a laparoscopic approach and 1:476 (95% CI, 1:365-1:620) for a robotic approach. There were 3369 patients with early cervical cancer undergoing radical hysterectomy with a mortality of 1:2049 (95% CI, 1:356-1:11 832). There were 3501 patients with endometrial cancer undergoing hysterectomy with lymph node dissection with a mortality of 1:195 (95% CI, 1:109-1:349). There were 418 patients with ovarian cancer undergoing MIS procedures with a mortality of 1 in 685 (95% CI, 1:44-1:10971). Eleven studies with 4037 patients compared mortality of gynecologic oncology surgery of any type (laparoscopic [1:626] vs robotic [1:716] for a relative risk of 1.12 [95% CI, 0.35-3.49])., Conclusion: The overall operative mortality for minimally invasive surgery in gynecologic oncology is 1 in 381 (95% CI, 1:306-1:474). For patients with early cervical cancer, it is 1:2049 (95% CI, 1:356-1: 11832), for endometrial cancer with node dissection it is 1:195 (95% CI, 1:109-1:349), and for ovarian cancer it is 1 in 685 (95% CI, 1:44-1:10 971). There is no difference between the type of MIS approach for patients undergoing any type of gynecologic oncology surgery., (Copyright © 2019 AAGL. Published by Elsevier Inc. All rights reserved.)
- Published
- 2019
- Full Text
- View/download PDF
30. The benefits of a standardized approach to opioid prescribing.
- Author
-
Patchett D, Grover M, Kresin M, Bryan M, Nordrum J, Buras M, Pierce S, and McDaniel K
- Subjects
- Analgesics, Opioid therapeutic use, Arizona epidemiology, Humans, Analgesics, Opioid administration & dosage, Chronic Pain drug therapy, Opioid Epidemic, Practice Patterns, Physicians' standards
- Abstract
This initiative increased patient acceptance of controlled substance agreements and random urine drug screening, and it led many patients to discontinue opioid therapy.
- Published
- 2019
31. Auto-obliteration of maxillary sinuses through osteoneogenesis in children with cystic fibrosis: A possible new way to reduce morbidity.
- Author
-
Buras M, Simoncini A, and Gungor A
- Subjects
- Adolescent, Child, Child, Preschool, Chronic Disease, Cystic Fibrosis diagnostic imaging, Humans, Maxillary Sinus diagnostic imaging, Osteogenesis, Retrospective Studies, Rhinitis diagnostic imaging, Rhinitis etiology, Sinusitis diagnostic imaging, Sinusitis etiology, Tomography, X-Ray Computed, Cystic Fibrosis complications, Endoscopy, Maxillary Sinus surgery, Rhinitis surgery, Sinusitis surgery
- Abstract
Background: Cystic Fibrosis is an autosomal recessive disorder with a mutation in the cystic fibrosis transmembrane regulator gene, leading to dysregulation of epithelial fluid transport, dehydration of airway surfaces and impaired mucociliary function in the sinuses, lungs, pancreas and other organs. This leads to thickened secretion which blocks the sinus ostia and promotes chronic bacterial overgrowth and destruction of the mucosa. Chronic rhinosinusitis in cystic fibrosis patients leads to a decreased quality of life involving increased hospitalizations, infections, pneumonia, and acute exacerbations, warranting multiple sinus surgeries. This study investigates the effects of a more aggressive surgical approach on reducing the need for repeat surgeries., Methods: A retrospective review of CT scans of nine cystic fibrosis patients who have had aggressive endoscopic sinus surgery for the treatment of chronic rhinosinusitis (CRS) was performed. The decrease in maxillary sinus volume was measured using pre-operative and post-operative scans., Results: A significant decrease in maxillary sinus volume was observed in all subjects. Volume reduction occurred through osteoneogenesis, causing auto-obliteration of the sinuses with cancellous bone., Conclusions: Aggressive endoscopic sinus surgery for maxillary sinuses incites an osteoneogenetic reaction that leads to auto-obliteration of the sinus and reduces sinus-related morbidity in children with cystic fibrosis. Through this osteoneogenesis, the sinus is transformed into a shallow cup that does not retain secretions and is easy to clear. It is our impression that this may lead to reduced morbidity and a decreased need for repeat maxillary sinus surgery., (Published by Elsevier Inc.)
- Published
- 2018
- Full Text
- View/download PDF
32. Relation of Telemetry Use and Mortality Risk, Hospital Length of Stay, and Readmission Rates in Patients With Respiratory Illness.
- Author
-
Dawson N, Burton MC, Hull B, Beliles G, Pritchard I, Trautman C, Ferry L, Doyon A, Colby R, Chuu A, Kung ST, Khang T, Durocher D, Buras M, Kosiorek H, Agrwal N, Sen A, Goss D, and Geyer H
- Subjects
- Acute Disease, Aged, Cardiovascular Diseases diagnosis, Cardiovascular Diseases etiology, Diagnosis-Related Groups, Female, Follow-Up Studies, Hospital Mortality trends, Humans, Incidence, Male, Respiratory Tract Diseases mortality, Retrospective Studies, Risk Factors, Survival Rate trends, United States epidemiology, Cardiovascular Diseases epidemiology, Length of Stay trends, Patient Readmission trends, Respiratory Tract Diseases diagnosis, Risk Assessment, Telemetry methods
- Abstract
The 2004 American Heart Association expert opinion-based guidelines restrict telemetry use primarily to patients with current or high-risk cardiac conditions. Respiratory infections have emerged as a common source of hospitalization, and telemetry is frequently applied without indication in efforts to monitor patient decompensation. In this retrospective study, we aimed to determine whether telemetry impacts mortality risk, length of stay (LOS), or readmission rates in hospitalized patients with acute respiratory infection not meeting American Heart Association criteria. A total of 765 respiratory infection patient encounters with Diagnosis-Related Groups 193, 194, 195, 177, 178 and 179 admitted in 2013 to 2015 to 2 tertiary community-based medical centers (Mayo Clinic, Arizona, and Mayo Clinic, Florida) were evaluated, and outcomes between patients who underwent or did not undergo telemetry were compared. Overall, the median LOS was longer in patients who underwent telemetry (3.0 days vs 2.0 days, p <0.0001). No differences between cohorts were noted in 30-day readmission rates (0.6% vs 1.3%, p = 0.32), patient mortality while hospitalized (0.6% vs 1.3%, p = 0.44), mortality at 30 days (7.9% vs 7.7%, p = 0.94), or mortality at 90 days (13.5% vs 13.5%, p = 0.99). Telemetry predicted LOS for both univariate (estimate 1.18, 95% confidence interval 1.06 to 1.32, p = 0.003) and multivariate (estimate 1.17, 95% confidence interval 1.06 to 1.30, p = 0.003) analyses after controlling for severity of illness but did not predict patient mortality. In conclusion, this study identified that patients with respiratory infection who underwent telemetry without clear indications may face increased LOS without reducing their readmission risk or improving the overall mortality., (Copyright © 2017 Elsevier Inc. All rights reserved.)
- Published
- 2017
- Full Text
- View/download PDF
33. A-SIDE: Video simulation of teen alcohol and marijuana use contexts.
- Author
-
Anderson KG, Brackenbury L, Quackenbush M, Buras M, Brown SA, and Price J
- Subjects
- Adolescent, Adolescent Behavior, Attitude, Female, Humans, Male, Motivation, Young Adult, Alcohol Drinking psychology, Decision Making, Marijuana Smoking psychology, Videotape Recording
- Abstract
Objective: This investigation examined the concurrent validity of a new video simulation assessing adolescent alcohol and marijuana decision making in peer contexts (A-SIDE)., Method: One hundred eleven youth (60% female; age 14-19 years; 80% White, 12.6% Latino; 24% recruited from treatment centers) completed the A-SIDE simulation, self-report measures of alcohol and marijuana use and disorder symptoms, and measures of alcohol (i.e., drinking motives and expectancies) and marijuana (i.e., expectancies) cognitions in the laboratory., Results: Study findings support concurrent associations between behavioral willingness to use alcohol and marijuana on the simulation and current use variables as well as on drinking motives and marijuana expectancies. Relations with use variables were found even when sample characteristics were controlled. Interestingly, willingness to accept nonalcoholic beverages (e.g., soda) and food offers in the simulation were inversely related to recent alcohol and marijuana use behavior., Conclusions: These findings are consistent with prior work using laboratory simulations with college students and provide preliminary validity evidence for this procedure. Future work is needed to examine the predictive utility of the A-SIDE with larger and more diverse samples of youth.
- Published
- 2014
- Full Text
- View/download PDF
34. C-SIDE: drinking simulation for college students.
- Author
-
Anderson KG, Duncan K, Buras M, Packard CD, and Kennedy C
- Subjects
- Adolescent, Alcohol Drinking epidemiology, Decision Making, Female, Follow-Up Studies, Humans, Male, Motivation, Play and Playthings, Predictive Value of Tests, Risk-Taking, Universities, Young Adult, Alcohol Drinking psychology, Alcohol-Related Disorders epidemiology, Computer Simulation, Students psychology
- Abstract
Objective: Our goals were to develop a realistic simulation of collegiate drinking contexts and evaluate the predictive validity of this methodology., Method: After methods development, 88 incoming students (61% women) completed measures of alcohol consumption, alcohol expectancies and motives, and the Collegiate-Simulated Intoxication Digital Elicitation (C-SIDE). Eight months later, students reported recent drinking behavior and alcohol-related consequences., Results: Willingness to drink alcohol on the C-SIDE predicted high-risk drinking at the end of the students' first year above and beyond baseline consumption. Accepting offers of food/nonalcoholic beverages across contexts predicted lower scores on the Alcohol Use Disorders Identification Test 8 months later. Drinking game contexts elicited different levels of behavioral willingness; a game with explicit heckling elicited less drinking willingness than one in a smaller and more casual environment., Conclusions: These findings support the integration of social context into the assessment of alcohol-related decision making and the further development of strategies to understand context-dependent phenomena.
- Published
- 2013
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.