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1. Use of furosemide in preterm neonates with acute kidney injury is associated with increased mortality: results from the TINKER registry

Author

Raina, Rupesh, Sethi, Sidharth Kumar, Agrawal, Gopal, Wazir, Sanjay, Bajaj, Naveen, Gupta, Naveen Parkash, Tibrewal, Abhishek, Vadhera, Ananya, Mirgunde, Shishir, Balachandran, Binesh, Sahoo, Jagdish, Afzal, Kamran, Shrivastava, Anubha, Bagla, Jyoti, Krishnegowda, Sushma, Konapur, Ananth, Soni, Kritika, Alhasan, Khalid, McCulloch, Mignon, and Bunchman, Timothy

Published
2024
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3. Nutrition in critically ill children with acute kidney injury on continuous kidney replacement therapy: a 2023 executive summary

Author

Raina, Rupesh, Suchan, Andrew, Soundararajan, Anvitha, Brown, Ann-Marie, Davenport, Andrew, Shih, Weiwen V., Nada, Arwa, Irving, Sharon Y., Mannemuddhu, Sai Sudha, Vitale, Victoria S., Crugnale, Aylin S., Keller, Gerri L., Berry, Katarina G., Zieg, Jakub, Alhasan, Khalid, Guzzo, Isabella, Lussier, Natalie H., Yap, Hui Kim, Bunchman, Timothy E., and Sethi, Sidharth K.

Published
2024
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4. Anticoagulation in patients with acute kidney injury undergoing kidney replacement therapy

Author

Raina, Rupesh, Chakraborty, Ronith, Davenport, Andrew, Brophy, Patrick, Sethi, Sidharth, McCulloch, Mignon, and Bunchman, Timothy

Subjects
Kidneys -- Transplantation, Anticoagulants (Medicine) -- Dosage and administration, Acute renal failure -- Care and treatment -- Demographic aspects, Health
Abstract

Kidney replacement therapy (KRT) is used to provide supportive therapy for critically ill patients with severe acute kidney injury and various other non-renal indications. Modalities of KRT include continuous KRT (CKRT), intermittent hemodialysis (HD), and sustained low efficiency daily dialysis (SLED). However, circuit clotting is a major complication that has been investigated extensively. Extracorporeal circuit clotting can cause reduction in solute clearances and can cause blood loss, leading to an upsurge in treatment costs and a rise in workload intensity. In this educational review, we discuss the pathophysiology of the clotting cascade within an extracorporeal circuit and the use of various types of anticoagulant methods in various pediatric KRT modalities., Author(s): Rupesh Raina [sup.1] [sup.2] , Ronith Chakraborty [sup.1] [sup.2] , Andrew Davenport [sup.3] , Patrick Brophy [sup.4] , Sidharth Sethi [sup.5] , Mignon McCulloch [sup.6] , Timothy Bunchman [sup.7] [...]

Published
2022
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6. Validation of the STARZ neonatal acute kidney injury risk stratification score

Author

Sethi, Sidharth Kumar, Raina, Rupesh, Rana, Abhyuday, Agrawal, Gopal, Tibrewal, Abhishek, Bajaj, Naveen, Gupta, Naveen Parkash, Mirgunde, Shishir, Sahoo, Jagdish, Balachandran, Binesh, Afzal, Kamran, Shrivastava, Anubha, Bagla, Jyoti, Krishnegowda, Sushma, Konapur, Ananth, Soni, Kritika, Sharma, Divya, Khooblall, Amrit, Khooblall, Prajit, Bunchman, Timothy, and Wazir, Sanjay

Published
2022
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7. Acute kidney injury in pediatric hematopoietic cell transplantation: critical appraisal and consensus

Author

Raina, Rupesh, Abu-Arja, Rolla, Sethi, Sidharth, Dua, Richa, Chakraborty, Ronith, Dibb, James T., Basu, Rajit K., Bissler, John, Felix, Melvin Bonilla, Brophy, Patrick, Bunchman, Timothy, Alhasan, Khalid, Haffner, Dieter, Kim, Yap Hui, Licht, Christopher, McCulloch, Mignon, Menon, Shina, Onder, Ali Mirza, Khooblall, Prajit, Khooblall, Amrit, Polishchuk, Veronika, Rangarajan, Hemalatha, Sultana, Azmeri, and Kashtan, Clifford

Published
2022
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8. Point-of-care-Ultrasound (POCUS) Training Curriculum for Pediatric Nephrology: PCRRT-ICONIC Group Recommendations

Author

Sethi, Sidharth Kumar, primary, Mahan, John, additional, Hu, Jieji, additional, Koratala, Abhilash, additional, Soni, Kritika, additional, Singh, Yogen, additional, Abitbol, Carolyn, additional, DeFreitas, Marissa, additional, Reisinger, Nathaniel, additional, Argaiz, Eduardo R, additional, Yap, Hui Kim, additional, Badeli, Hamidreza, additional, Kalra, Meenal, additional, VanGeest, Jonathan, additional, Nair, Nikhil, additional, Raynor, James, additional, Alhasan, Khalid A, additional, McCulloch, Mignon, additional, Bunchman, Timothy, additional, Sharma, Vivek, additional, and Raina, Rupesh, additional

Published
2024
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9. Neonatal acute kidney injury risk stratification score: STARZ study

Author

Wazir, Sanjay, Sethi, Sidharth Kumar, Agarwal, Gopal, Tibrewal, Abhishek, Dhir, Rohan, Bajaj, Naveen, Gupta, Naveen Parkash, Mirgunde, Shishir, Sahoo, Jagdish, Balachandran, Binesh, Afzal, Kamran, Shrivastava, Anubha, Bagla, Jyoti, Krishnegowda, Sushma, Konapur, Ananth, Soni, Kritika, Rana, Abhyuday, Bunchman, Timothy, and Raina, Rupesh

Published
2022
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14. CRRT in a Sick Child

Author

Bunchman, Timothy E., Sethi, Sidharth Kumar, editor, Raina, Rupesh, editor, McCulloch, Mignon, editor, and Bunchman, Timothy E., editor

Published
2019
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17. Nutrition in Critically Ill Children with Acute Kidney Injury on Continuous Kidney Replacement Therapy: An Integrative Review and Clinical Practice Points 2023

Author

Raina, Rupesh, primary, Suchan, Andrew, additional, Sethi, Sidharth K, additional, Soundararajan, Anvitha, additional, Vitale, Victoria S, additional, Keller, Gerri L, additional, Brown, Ann-Marie, additional, Davenport, Andrew, additional, Shih, Weiwen V, additional, Nada, Arwa, additional, Irving, Sharon Y, additional, Mannemuddhu, Sai Sudha, additional, Crugnale, Aylin S, additional, Myneni, Archana, additional, Berry, Katarina G, additional, Zieg, Jakub, additional, Alhasan, Khalid, additional, Guzzo, Isabella, additional, Lussier, Natalie H, additional, Yap, Hui Kim, additional, and Bunchman, Timothy E, additional

Published
2023
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18. Post-transplant Recurrence of Focal Segmental Glomerulosclerosis: Consensus Statements

Author

Raina, Rupesh, primary, Jothi, Swathi, additional, Haffner, Dieter, additional, Somers, Michael, additional, Filler, Guido, additional, Vasistha, Prabhav, additional, Chakraborty, Ronith, additional, Shapiro, Ron, additional, Randhawa, Parmjeet S., additional, Parekh, Rulan, additional, Licht, Christopher, additional, Bunchman, Timothy, additional, Sethi, Sidharth, additional, Mangat, Guneive, additional, Zaritsky, Joshua, additional, Schaefer, Franz, additional, Warady, Bradley, additional, Bartosh, Sharon, additional, McCulloch, Mignon, additional, Alhasan, Khalid, additional, Swiatecka-Urban, Agnieszka, additional, Smoyer, William E., additional, Chandraker, Anil, additional, Yap, Hui Kim, additional, Jha, Vivekananda, additional, Bagga, Arvind, additional, and Radhakrishnan, Jai, additional

Published
2023
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20. Prevention of dialysis disequilibrium syndrome in children with advanced uremia with a structured hemodialysis protocol: A quality improvement initiative study.

Author

Sethi, Sidharth Kumar, Luyckx, Valerie, Bunchman, Timothy, Nair, Aishwarya, Bansal, Shyam Bihari, Pember, Bryce, Soni, Kritika, Savita, Yadav, Dinesh Kumar, Sharma, Vivek, Alhasan, Khalid, and Raina, Rupesh

Subjects
SYNDROMES in children, DIALYSIS (Chemistry), HEMODIALYSIS, UREMIA, CHILD patients
Abstract

Background: Dialysis disequilibrium syndrome (DDS) is a rare but significant concern in adult and pediatric patients undergoing dialysis initiation with advanced uremia or if done after an interval. It is imperative to gain insights into the epidemiological patterns, pathophysiological mechanisms, and preventive strategies aimed at averting the onset of this ailment. Design: Prospective observational quality improvement initiative cohort study. Setting and Participants: A prospective single‐center study involving 50 pediatric patients under 18 years recently diagnosed with chronic kidney disease stage V with blood urea ≥200 mg/dL, admitted to our tertiary care center for dialysis initiation from January 2017 to October 2023. Quality Improvement Plan: A standardized protocol was developed and followed for hemodialysis in pediatric patients with advanced uremia. This protocol included measures such as lower urea reduction ratios (targeted at 20%–30%) with shorter dialysis sessions and linear dialysate sodium profiling. Prophylactic administration of mannitol and 25% dextrose was also done to prevent the incidence of dialysis disequilibrium syndrome. Measures: Incidence of dialysis disequilibrium syndrome and severe dialysis disequilibrium syndrome, mortality, urea reduction ratios (URRs), neurological outcome at discharge, and development of complications such as infection and hypotension. Long‐term outcomes were assessed at the 1‐year follow‐up including adherence to dialysis, renal transplantation, death, and loss to follow‐up. Results: The median serum creatinine and urea levels at presentation were 7.93 and 224 mg/dL, respectively. A total of 20% of patients had neurological symptoms attributable to advanced uremia at the time of presentation. The incidence of dialysis disequilibrium syndrome was 4% (n = 2) with severe dialysis disequilibrium syndrome only 2% (n = 1). Overall mortality was 8% (n = 4) but none of the deaths were attributed to dialysis disequilibrium syndrome. The mean urea reduction ratios for the first, second, and third dialysis sessions were 23.45%, 34.56%, and 33.50%, respectively. The patients with dialysis disequilibrium syndrome were discharged with normal neurological status. Long‐term outcomes showed 88% adherence to dialysis and 38% renal transplantation. Limitations: This study is characterized by a single‐center design, nonrandomized approach, and limited sample size. Conclusions: Our structured protocol served as a framework for standardizing procedures contributing to low incidence rates of dialysis disequilibrium syndrome. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Consensus guidelines for management of hyperammonaemia in paediatric patients receiving continuous kidney replacement therapy

Author

Raina, Rupesh, Bedoyan, Jirair K., Lichter-Konecki, Uta, Jouvet, Philippe, Picca, Stefano, Mew, Nicholas Ah, Machado, Marcel C., Chakraborty, Ronith, Vemuganti, Meghana, Grewal, Manpreet K., Bunchman, Timothy, Sethi, Sidharth Kumar, Krishnappa, Vinod, McCulloch, Mignon, Alhasan, Khalid, Bagga, Arvind, Basu, Rajit K., Schaefer, Franz, Filler, Guido, and Warady, Bradley A.

Published
2020
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22. Renal replacement therapy in the management of intoxications in children: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) workgroup

Author

Raina, Rupesh, Grewal, Manpreet K, Blackford, Martha, Symons, Jordan M., Somers, Michael J. G., Licht, Christoph, Basu, Rajit K, Sethi, Sidharth Kumar, Chand, Deepa, Kapur, Gaurav, McCulloch, Mignon, Bagga, Arvind, Krishnappa, Vinod, Yap, Hui-Kim, de Sousa Tavares, Marcelo, Bunchman, Timothy E, Bestic, Michelle, Warady, Bradley A, and de Ferris, Maria Díaz-González

Published
2019
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25. Use of furosemide in preterm neonates with acute kidney injury is associated with increased mortality: results from the TINKER registry

Author

Raina, Rupesh, primary, Sethi, Sidharth Kumar, additional, Agrawal, Gopal, additional, Wazir, Sanjay, additional, Bajaj, Naveen, additional, Gupta, Naveen Parkash, additional, Tibrewal, Abhishek, additional, Vadhera, Ananya, additional, Mirgunde, Shishir, additional, Balachandran, Binesh, additional, Sahoo, Jagdish, additional, Afzal, Kamran, additional, Shrivastava, Anubha, additional, Bagla, Jyoti, additional, Krishnegowda, Sushma, additional, Konapur, Ananth, additional, Soni, Kritika, additional, Alhasan, Khalid, additional, McCulloch, Mignon, additional, and Bunchman, Timothy, additional

Published
2023
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26. Post-transplant recurrence of focal segmental glomerular sclerosis: consensus statements

Author

Raina, Rupesh, Jothi, Swathi, Haffner, Dieter, Somers, Michael, Filler, Guido, Vasistha, Prabhav, Chakraborty, Ronith, Shapiro, Ron, Randhawa, Parmjeet S., Parekh, Rulan, Licht, Christopher, Bunchman, Timothy, Sethi, Sidharth, Mangat, Guneive, Zaritsky, Joshua, Schaefer, Franz, Warady, Bradley, Bartosh, Sharon, McCulloch, Mignon, Alhasan, Khalid, Swiatecka-Urban, Agnieszka, Smoyer, William E., Chandraker, Anil, Yap, Hui Kim, Jha, Vivekanand, Bagga, Arvind, and Radhakrishnan, Jai

Published
2024
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30. Switching from continuous veno‐venous hemodiafiltration to intermittent sustained low‐efficiency daily hemodiafiltration (SLED‐f) in pediatric acute kidney injury: A prospective cohort study

Author

Sethi, Sidharth Kumar, primary, Raina, Rupesh, additional, Bansal, Shyam Bihari, additional, Soundararajan, Anvitha, additional, Dhaliwal, Maninder, additional, Raghunathan, Veena, additional, Kalra, Meenal, additional, Soni, Kritika, additional, Mahato, Samit Kumar, additional, Vadhera, Ananya, additional, Yadav, Dinesh Kumar, additional, and Bunchman, Timothy, additional

Published
2023
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32. Contributors

Author

Albright, Robert C., primary, Amerling, Richard, additional, Angeli, Paolo, additional, Angelotti, Maria Lucia, additional, Antonelli, Massimo, additional, Antoniotti, Riccardo, additional, Arulkumaran, Nishkantha, additional, Asfar, Pierre, additional, Ash, Stephen R., additional, Aucella, Filippo, additional, Aucella, Francesco, additional, Ave, Samuele, additional, Bagshaw, Sean M., additional, Balaraman, Vasanthi, additional, Baldwin, Ian, additional, Bargman, Joanne M., additional, Barletta, Gina-Marie, additional, Barletta, Jeffrey F., additional, Barnela, Shriganesh R., additional, Bayır, Hülya, additional, Beaulieu, Monica, additional, Bellasi, Antonio, additional, Bellomo, Rinaldo, additional, Beloncle, François, additional, Bhansali, Arjun, additional, Bihorac, Azra, additional, Billings, Frederic T., additional, Birk, Horst-Walter, additional, Bonilla-Reséndiz, Luis Ignacio, additional, Bouchard, Josée, additional, Bourke, Edmund, additional, Braitberg, George, additional, Brendolan, Alessandra, additional, Brocca, Alessandra, additional, Brophy, Patrick D., additional, Bucala, Richard, additional, Bunchman, Timothy E., additional, Burdmann, Emmanuel A., additional, Busse, Laurence W., additional, Caires, Renato Antunes, additional, Caironi, Pietro, additional, Camilla, Roberta, additional, Campos, Israel, additional, Canaud, Bernard, additional, Cantaluppi, Vincenzo, additional, Martinez, Maria P., additional, Capasso, Giovambattista, additional, Carcillo, Joseph A., additional, Carlesso, Eleonora, additional, Casino, Francesco G., additional, Castellano, Giuseppe, additional, Catania, Matteo, additional, Cawcutt, Kelly A., additional, Cerda, Jorge, additional, Charen, Elliot, additional, Chawla, Lakhmir S., additional, Chiaramonte, Stefano, additional, Chua, Horng-Ruey, additional, Cianciaruso, Bruno, additional, Ciceri, Paola, additional, Cieslak, Jacek, additional, Clark, William R., additional, Claure-Del Granado, Rolando, additional, Clementi, Anna, additional, Co, Ivan N., additional, Coelho, Fernanda Oliveira, additional, Conte, Ferruccio, additional, Corey, Howard E., additional, Cosmai, Laura, additional, Costalonga, Elerson Carlos, additional, Costamagna, Andrea, additional, Costanzo, Maria Rosa, additional, Cozzolino, Mario, additional, Cramer, Carl H., additional, Cravedi, Paolo, additional, Crepaldi, Carlo, additional, Creteur, Jacques, additional, Crew, R. John, additional, da Costa e Silva, Verônica Torres, additional, Davenport, Andrew, additional, Davies, Andrew R., additional, D'Costa, Rohit, additional, Dean, Dawson F., additional, Debiais, Charlotte, additional, de Cal, Massimo, additional, Dedhia, Paras, additional, de Grooth, Harm-Jan, additional, Dell'Aquila, Roberto, additional, Dellepiane, Sergio, additional, Dellinger, Richard Phillip, additional, Del Vecchio, Lucia, additional, Depner, Thomas A., additional, De Rosa, Silvia, additional, Deutschman, Clifford S., additional, Devarajan, Prasad, additional, Dewitte, A., additional, Di Iorio, Biagio R., additional, Di Lullo, Luca, additional, Di Micco, Lucia, additional, Di Nardo, Matteo, additional, Ding, Xiaoqiang, additional, D'Ippoliti, Fiorella, additional, Di Somma, Salvatore, additional, Doi, Kent, additional, Dries, David J., additional, Druml, Wilfred, additional, Duke, Graeme, additional, Durand, Francois, additional, Eadon, Michael T., additional, Eckstein, Devin, additional, Egi, Moritoki, additional, Eiam-Ong, Somchai, additional, Elbers, Paul W.G., additional, Elli, Francesca, additional, Elliott, Steve, additional, Emlet, David R., additional, Endre, Zoltan, additional, Evans, Roger G., additional, Fanelli, Vito, additional, Fattahi, Fatemeh, additional, Federspiel, Christine Kinggaard, additional, Ferrada, Marcela A., additional, Ferrari, Fiorenza, additional, Fiaccadori, Enrico, additional, Fiorentino, Marco, additional, Fisher, Caleb, additional, Flessner, Michael F., additional, Formica, Marco, additional, Forni, Lui G., additional, Francoz, Claire, additional, French, Craig, additional, Fuhrman, Dana Y., additional, Fumagalli, Giordano, additional, Galbusera, Miriam, additional, Gallieni, Maurizio, additional, Gammill, Hilary S., additional, Gao, Dayong, additional, Garzotto, Francesco, additional, Gatta, Giuseppe, additional, Genga, Kelly R., additional, Genovesi, Simonetta, additional, Genyk, Yuri S., additional, Geradin, Christel, additional, Gesualdo, Loreto, additional, Giavarina, Davide, additional, Giuliani, Anna, additional, Glezerman, Ilya G., additional, Goldstein, Stuart L., additional, Golper, Thomas A., additional, Gómez, Hernando, additional, Granata, Antonio, additional, Grandaliano, Giuseppe, additional, Grasselli, Giacomo, additional, Groeneveld, A.B. Johan, additional, Guerci, Philippe, additional, Gunnerson, Kyle J., additional, Harbord, Nikolas, additional, Harshman, Lyndsay A., additional, Hennessy, Anthony J., additional, Hill, Graham L., additional, Hobson, Charles, additional, Hohenstein, Bernd, additional, Honoré, Patrick M., additional, Horwitz, Edward, additional, Hosseinian, Leila, additional, Hoste, Eric A.J., additional, House, Andrew A., additional, Humes, H. David, additional, Husain-Syed, Faeq, additional, Ince, Can, additional, Ing, Todd S., additional, Jacobs, Rita, additional, Jaswal, Dharmvir, additional, Jeyabalan, Arun, additional, Joannes-Boyau, Olivier, additional, Joannidis, Michael, additional, Joyce, Emily, additional, Kane-Gill, Sandra L., additional, Kaplan, Lewis J., additional, Kashani, Kianoush, additional, Katz, Nevin, additional, Kellum, John A., additional, Khanna, Ramesh, additional, Kim-Campbell, Nahmah, additional, King, Joshua D., additional, Kirwan, Christopher J., additional, Kiss, Joseph E., additional, Klein, David, additional, Kotanko, Peter, additional, Krediet, Raymond T., additional, Kuhlmann, Martin K., additional, Kuiper, Jan Willem, additional, Lachance, Philippe, additional, Lameire, Norbert, additional, Langer, Thomas, additional, Lankadeva, Yugeesh R., additional, Laurin, Louis-Philippe, additional, Lazzeri, Elena, additional, Leblanc, Martine, additional, Lefebvre, Joannie, additional, Lentini, Paolo, additional, Leray-Moragués, Hélène, additional, Levin, Adeera, additional, Lew, Susie Q., additional, Liapis, Helen, additional, Liu, Kathleen D., additional, Livigni, Sergio, additional, Locatelli, Francesco, additional, Lorenzin, Anna, additional, Lu, Jian-Da, additional, Lu, Renhua, additional, Lysak, Nicholas, additional, Macedo, Etienne, additional, Madan, Niti, additional, Madore, François, additional, Maerz, Linda L., additional, Maiden, Matthew J., additional, Malhotra, Rakesh, additional, Marengo, Marita, additional, Mariano, Filippo, additional, Marik, Paul E., additional, Marini, John J., additional, Marino, Rossella, additional, Marshall, Mark R., additional, Mårtensson, Johan, additional, Matsuura, Ryo, additional, May, Clive N., additional, Mazzone, Patrizio, additional, McCauley, Jerry, additional, McCullough, Peter A., additional, McMahon, Blaithin A., additional, Mehta, Ravindra L., additional, Mele, Caterina, additional, Menon, Madhav, additional, Meola, Mario, additional, Mérouani, Aicha, additional, Meuwly, Jean-Yves, additional, Milla, Paola, additional, Misra, Madhukar, additional, Misra, Paraish S., additional, Mizock, Barry A., additional, Modi, Jwalant R., additional, Moeckel, Gilbert, additional, Molitoris, Bruce A., additional, Morabito, Santo, additional, Mucelli, Roberto Pozzi, additional, Murray, Patrick T., additional, Murugan, Raghavan, additional, Nadim, Mitra K., additional, Nair, Devika, additional, Nalesso, Federico, additional, Neri, Mauro, additional, Nguyen, Trung C., additional, Ni, Zhaohui, additional, Noris, Marina, additional, Novick, Tessa, additional, O'Horo, John C., additional, Okusa, Mark Douglas, additional, Opal, Steven M., additional, Opdam, Helen Ingrid, additional, Ostermann, Marlies, additional, Ottaviano, Emerenziana, additional, Oudemans-van Straaten, Heleen M., additional, Overgaard-Steensen, Christian, additional, Padalino, Massimo A., additional, Panichi, Vincenzo, additional, Parameswaran, Priyanka, additional, Patel, Samir S., additional, Payen, Didier, additional, Pea, Federico, additional, Peacock, W. Frank, additional, Peart, Sandrica Young, additional, Peerapornratana, Sadudee, additional, Pelosi, Paolo, additional, Peng, Zhi-Yong, additional, Perico, Norberto, additional, Peruzzi, Licia, additional, Pesce, Francesco, additional, Pesenti, Antonio, additional, Petrucci, Ilaria, additional, Pham, Phuong-Chi, additional, Pham, Phuong-Thu, additional, Phoon, Richard K.S., additional, Piano, Salvatore, additional, Pinsky, Michael R., additional, Piquilloud, Lise, additional, Pistolesi, Valentina, additional, Plank, Lindsay D., additional, Plötz, Frans B., additional, Podestá, Manuel Alfredo, additional, Porta, Camillo, additional, Pozzato, Marco, additional, Prencipe, Michele, additional, Prowle, John R., additional, Puthucheary, Zudin A., additional, Qu, Lirong, additional, Rachoin, Jean-Sebastien, additional, Radhakrishnan, Jai, additional, Ranieri, V. Marco, additional, Ratanarat, Ranistha, additional, Remuzzi, Giuseppe, additional, Resnick, Shelby, additional, Rewa, Oleksa G., additional, Ricci, Zaccaria, additional, Ridel, Christophe, additional, Rifai, Kinan, additional, Ring, Troels, additional, Rizo-Topete, Lilia M., additional, Roessler, Eric, additional, Romagnani, Paola, additional, Romagnoli, Stefano, additional, Ronco, Claudio, additional, Ronco, Federico, additional, Rosner, Mitchell H., additional, Rossetti, Emanuele, additional, Russell, James A., additional, Saab, Georges, additional, Sabatino, Alice, additional, Saboo, Sonali S., additional, Samoni, Sara, additional, Sappington, Penny Lynn, additional, Sartori, Marco, additional, Savige, Judy, additional, Schena, Francesco Paolo, additional, Schneider, Antoine Guillaume, additional, Schraverus, Pieter, additional, Schulte, Wibke, additional, Segoloni, Giuseppe, additional, Semler, Matthew W., additional, Sharma, Aashish, additional, Shaw, Andrew, additional, Sheth, Naitik, additional, Shukla, Ashutosh, additional, Siddall, Eric C., additional, Sievers, Theodore M., additional, Siew, Edward D., additional, Singbartl, Kai, additional, Singer, Mervyn, additional, Singh, Pooja, additional, Smith, Loren E., additional, Soni, Sachin S., additional, Soto, Mara Serrano, additional, Spapen, Herbert D., additional, Srisawat, Nattachai, additional, Srivastava, Ajay, additional, Stellin, Giovanni, additional, Symons, Jordan M., additional, Szamosfalvi, Balazs, additional, Tai, Kian Bun, additional, Takalkar, Unmesh V., additional, Teitelbaum, Isaac, additional, Tetta, Ciro, additional, Thakar, Charuhas V., additional, Tonon, Marta, additional, Trepiccione, Francesco, additional, Triulzi, Darrell, additional, Tushar, Chopra, additional, Uchino, Shigehiko, additional, Valika, Ali, additional, Van Biesen, Wim, additional, Vandenberghe, Wim, additional, Vanholder, Raymond, additional, Vanmassenhove, Jill, additional, Verbine, Anton, additional, Vergano, Marco, additional, Villa, Gianluca, additional, Villeneuve, Pierre-Marc, additional, Vincent, Jean-Louis, additional, Vinsonneau, Christophe, additional, Virzì, Grazia Maria, additional, Visconti, Federico, additional, Visvanathan, Ravindran, additional, Van Vong, Li, additional, Walmrath, Hans-Dieter, additional, Ward, Peter A., additional, Weir, Matthew A., additional, Wen, Xiaoyan, additional, Wendon, Julia, additional, Winchester, James Frank, additional, Wong, Adrian, additional, Woodhouse, Elke L., additional, Xue, Jun, additional, Yadav, Anju, additional, Yerram, Preethi, additional, Yessayan, Lenar, additional, Yeun, Jane Y., additional, Yu, Alex W., additional, Zaccaria, Marta, additional, Zacchia, Miriam, additional, Zachariah, Teena P., additional, Zamperetti, Nereo, additional, Zampieri, Fernando G., additional, Zanco, Pierluigi, additional, Zanella, Alberto, additional, Zanoli, Luca, additional, Zappitelli, Michael, additional, Zaragoza, Jose J., additional, Zarbock, Alexander, additional, Zaroccolo, Marta, additional, Zhang, Han, additional, and Zimmer, Andrea, additional

Published
2019
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33. Prolonged intermittent renal replacement therapy in children

Author

Sinha, Rajiv, Sethi, Sidharth Kumar, Bunchman, Timothy, Lobo, Valentine, and Raina, Rupesh

Subjects
Children -- Diseases, Acute renal failure -- Diagnosis -- Care and treatment, Acute renal failure in children -- Diagnosis -- Care and treatment, Health
Abstract

Wide ranges of age and weight in pediatric patients makes renal replacement therapy (RRT) in acute kidney injury (AKI) challenging, particularly in the pediatric intensive care unit (PICU), wherein children are often hemodynamically unstable. Standard hemodialysis (HD) is difficult in this group of children and continuous veno-venous hemofiltration/dialysis (CVVH/D) has been the accepted modality in the developed world. Unfortunately, due to cost constraints, CVVH/D is often not available and peritoneal dialysis (PD) remains the common mode of RRT in resource-poor facilities. Acute PD has its drawbacks, and intermittent HD (IHD) done slowly over a prolonged period has been explored as an alternative. Various modes of slow sustained IHD have been described in the literature with the recently introduced term prolonged intermittent RRT (PIRRT) serving as an umbrella terminology for all of these modes. PIRRT has been widely accepted in adults with studies showing it to be as effective as CVVH/D but with an added advantage of being more cost-effective. Pediatric data, though scanty, has been promising. In this current review, we elaborate on the practical aspects of undertaking PIRRT in children as well as summarize its current status., Author(s): Rajiv Sinha [sup.1] , Sidharth Kumar Sethi [sup.2] , Timothy Bunchman [sup.3] , Valentine Lobo [sup.4] , Rupesh Raina [sup.5] Author Affiliations: (1) 0000 0004 1801 0469, grid.414710.7, Institute [...]

Published
2018
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34. Validation of the STARZ neonatal acute kidney injury risk stratification score in an independent prospective cohort

Author

Dhooria, Gurdeep Singh, primary, Nautiyal, Arushi, additional, Wazir, Sanjay, additional, Agrawal, Gopal, additional, Tiwana, Anupreet, additional, Bajaj, Naveen, additional, Gupta, Naveen Parkash, additional, Mirgunde, Shishir, additional, Sahoo, Jagdish, additional, Balachandran, Binesh, additional, Afzal, Kamran, additional, Shrivastava, Anubha, additional, Bagla, Jyoti, additional, Krishnegowda, Sushma, additional, Konapur, Ananth, additional, Soni, Kritika, additional, McCulloch, Mignon, additional, Bunchman, Timothy, additional, Sethi, Sidharth Kumar, additional, and Raina, Rupesh, additional

Published
2022
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37. Renal Replacement Therapy

Author

Sreedhar, Sue S., Bunchman, Timothy E., Maxvold, Norma J., Wheeler, Derek S., editor, Wong, Hector R., editor, and Shanley, Thomas P., editor

Published
2014
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40. Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative

Author

Valentine, Stacey L., Bembea, Melania M., Muszynski, Jennifer A., Cholette, Jill M., Doctor, Allan, Spinella, Phillip C., Steiner, Marie E., Tucci, Marisa, Hassan, Nabil E., Parker, Robert I., Lacroix, Jacques, Argent, Andrew, Carson, Jeffrey L., Remy, Kenneth E., Demaret, Pierre, Emeriaud, Guillaume, Kneyber, Martin C. J., Guzzetta, Nina, Hall, Mark W., Macrae, Duncan, Karam, Oliver, Russell, Robert T., Stricker, Paul A., Vogel, Adam M., Tasker, Robert C., Turgeon, Alexis F., Schwartz, Steven M., Willems, Ariane, Josephson, Cassandra D., Luban, Naomi L. C., Lehmann, Leslie E., Stanworth, Simon J., Zantek, Nicole D., Bunchman, Timothy E., Cheifetz, Ira M., Fortenberry, James D., Delaney, Meghan, van de Watering, Leo, Robinson, Karen A., Malone, Sara, Steffen, Katherine M., and Bateman, Scot T.

Published
2018
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42. Corrigendum: PCRRT Expert Committee ICONIC position paper on prescribing kidney replacement therapy in critically sick children with acute liver failure

Author

Raina, Rupesh, primary, Sethi, Sidharth K., additional, Filler, Guido, additional, Menon, Shina, additional, Mittal, Aliza, additional, Khooblall, Amrit, additional, Khooblall, Prajit, additional, Chakraborty, Ronith, additional, Adnani, Harsha, additional, Vijayvargiya, Nina, additional, Teo, Sharon, additional, Bhatt, Girish, additional, Koh, Lee Jin, additional, Mourani, Chebl, additional, de Sousa Tavares, Marcelo, additional, Alhasan, Khalid, additional, Forbes, Michael, additional, Dhaliwal, Maninder, additional, Raghunathan, Veena, additional, Broering, Dieter, additional, Sultana, Azmeri, additional, Montini, Giovanni, additional, Brophy, Patrick, additional, McCulloch, Mignon, additional, Bunchman, Timothy, additional, Yap, Hui Kim, additional, Topalglu, Rezan, additional, and Díaz-González de Ferris, Maria, additional

Published
2022
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44. Ethical Considerations Concerning Amnioinfusions for Treating Fetal Bilateral Renal Agenesis

Author

Sugarman, Jeremy, Anderson, Jean, Baschat, Ahmet A., Herrera Beutler, Jaime, Bienstock, Jessica L., Bunchman, Timothy E., Desai, Niraj M., Gates, Elena, Goldberg, Aviva, Grimm, Paul C., Henry, Leslie Meltzer, Jelin, Eric B., Johnson, Emily, Hertenstein, Christine B., Mastroianni, Anna C., Mercurio, Mark R., Neu, Alicia, Nogee, Lawrence M., Polzin, William J., Ralston, Steven J., Ramus, Ronald M., Singleton, Megan Kasimatis, Somers, Michael J. G., Wang, Karen C., and Boss, Renee

Published
2018
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45. Extracorporeal treatments for isoniazid poisoning: Systematic review and recommendations from the EXTRIP workgroup

Author

Mowry, James, Shepherd, Greene, Hoffman, Robert, Lavergne, Valery, Gosselin, Sophie, Nolin, Thomas, Vijayan, Anitha, Kielstein, Jan, Roberts, Darren, Ghannoum, Marc, Alhatali, Badria, Anseeuw, Kurt, Bird, Steven, Berling, Ingrid, Bouchard, Josée, Bunchman, Timothy, Calello, Diane, Chin, Paul, Doi, Kent, Galvao, Tais, Goldfarb, David, Hassanian, Hossein, Hoegberg, Lotte, Kallab, Siba, Kebede, Sofia, Lewington, Andrew, Li, Yi, Macedo, Etienne, Maclaren, Rob, Mégarbane, Bruno, Ostermann, Marlies, Peng, Ai, Roy, Jean‐philippe, Walsh, Steven, Wong, Anselm, Wood, David, Yates, Christopher, Service de Réanimation Médicale et Toxicologique [Hôpital Lariboisière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Optimisation thérapeutique en Neuropsychopharmacologie (OPTeN (UMR_S_1144 / U1144)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Extracorporeal Treatments in Poisoning workgroup: Badria Alhatali, Kurt Anseeuw, Steven Bird, Ingrid Berling, Josée Bouchard, Timothy E Bunchman, Diane P Calello, Paul K Chin, Kent Doi, Tais Galvao, David S Goldfarb, Hossein Hassanian, Lotte C Hoegberg, Siba Kallab, Sofia Kebede, Andrew Lewington, Yi Li, Etienne M Macedo, Rob MacLaren, Bruno Megarbane, Marlies E Ostermann, Ai Peng, Jean-Philippe Roy, Steven J Walsh, Anselm Wong, David M Wood, Christopher Yates, and Mégarbane, Bruno

Subjects
0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, 030106 microbiology, 030204 cardiovascular system & hematology, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, Extracorporeal, 03 medical and health sciences, 0302 clinical medicine, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Renal Dialysis, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Internal medicine, Isoniazid, medicine, Animals, Humans, Pharmacology (medical), Dosing, Dialysis, [SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, business.industry, Poisoning, Pyridoxine, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [SDV.TOX] Life Sciences [q-bio]/Toxicology, Systematic review, [SDV.TOX]Life Sciences [q-bio]/Toxicology, Practice Guidelines as Topic, Cohort, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, Hemodialysis, business, medicine.drug
Abstract

Isoniazid toxicity from self-poisoning or dosing errors remains common in regions of the world where tuberculosis is prevalent. Although the treatment of isoniazid poisoning is centered on supportive care and pyridoxine administration, extracorporeal treatments (ECTRs), such as hemodialysis, have been advocated to enhance elimination of isoniazid. No systematic reviews or evidence-based recommendations currently exist on the benefit of ECTRs for isoniazid poisoning. The Extracorporeal Treatments in Poisoning (EXTRIP) workgroup systematically collected and rated the available evidence on the effect of and indications for ECTRs in cases of isoniazid poisoning. We conducted a systematic review of the literature, screened studies, extracted data on study characteristics, outcomes, and measurement characteristics, summarized findings, and formulated recommendations following published EXTRIP methods. Forty-three studies (two animal studies, 34 patient reports or patient series, and seven pharmacokinetic studies) met inclusion criteria. Toxicokinetic or pharmacokinetic analysis was available for 60 patients, most treated with hemodialysis (n = 38). The workgroup assessed isoniazid as "Moderately Dialyzable" by hemodialysis for patients with normal kidney function (quality of evidence = C) and "Dialyzable" by hemodialysis for patients with impaired kidney function (quality of evidence = A). Clinical data for ECTR in isoniazid poisoning were available for 40 patients. Mortality of the cohort was 12.5%. Historical controls who received modern standard care including appropriately dosed pyridoxine generally had excellent outcomes. No benefit could be extrapolated from ECTR, although there was evidence of added costs and harms related to the double lumen catheter insertion, the extracorporeal procedure itself, and the extracorporeal removal of pyridoxine. The EXTRIP workgroup suggests against performing ECTR in addition to standard care (weak recommendation, very low quality of evidence) in patients with isoniazid poisoning. If standard dose pyridoxine cannot be administered, we suggest performing ECTR only in patients with seizures refractory to GABAA receptor agonists (weak recommendation, very low quality of evidence).

Published
2021

46. Risk factors and outcomes of neonates with acute kidney injury needing peritoneal dialysis: Results from the prospective TINKER (The Indian PCRRT-ICONIC Neonatal Kidney Educational Registry) study

Author

Sethi, Sidharth Kumar, primary, Wazir, Sanjay, additional, Sahoo, Jagdish, additional, Agrawal, Gopal, additional, Bajaj, Naveen, additional, Gupta, Naveen Parkash, additional, Mirgunde, Shishir, additional, Balachandran, Binesh, additional, Afzal, Kamran, additional, Shrivastava, Anubha, additional, Bagla, Jyoti, additional, Krishnegowda, Sushma, additional, Konapur, Ananth, additional, Sultana, Azmeri, additional, Soni, Kritika, additional, Nair, Nikhil, additional, Sharma, Divya, additional, Khooblall, Prajit, additional, Pandey, Avisha, additional, Alhasan, Khalid, additional, McCulloch, Mignon, additional, Bunchman, Timothy, additional, Tibrewal, Abhishek, additional, and Raina, Rupesh, additional

Published
2022
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47. Renal replacement therapy in children

Author

Warady, Bradley A., Bunchman, Timothy E., Drukker, Parsons, Maher, Hörl, Walter H., editor, Koch, Karl M., editor, Lindsay, Robert M., editor, Ronco, Claudio, editor, and Winchester, James F., editor

Published
2004
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49. Supplemental Material, sj-docx-1-ptd-10.1177_08968608221091023 - Risk factors and outcomes of neonates with acute kidney injury needing peritoneal dialysis: Results from the prospective TINKER (The Indian PCRRT-ICONIC Neonatal Kidney Educational Registry) study

Author

Sethi, Sidharth Kumar, Wazir, Sanjay, Sahoo, Jagdish, Agrawal, Gopal, Bajaj, Naveen, Gupta, Naveen Parkash, Mirgunde, Shishir, Balachandran, Binesh, Afzal, Kamran, Shrivastava, Anubha, Bagla, Jyoti, Krishnegowda, Sushma, Konapur, Ananth, Sultana, Azmeri, Soni, Kritika, Nair, Nikhil, Sharma, Divya, Khooblall, Prajit, Pandey, Avisha, Alhasan, Khalid, McCulloch, Mignon, Bunchman, Timothy, Tibrewal, Abhishek, and Raina, Rupesh

Subjects
Medicine
Abstract

Supplemental Material, sj-docx-1-ptd-10.1177_08968608221091023 for Risk factors and outcomes of neonates with acute kidney injury needing peritoneal dialysis: Results from the prospective TINKER (The Indian PCRRT-ICONIC Neonatal Kidney Educational Registry) study by Sidharth Kumar Sethi, Sanjay Wazir, Jagdish Sahoo, Gopal Agrawal, Naveen Bajaj, Naveen Parkash Gupta, Shishir Mirgunde, Binesh Balachandran, Kamran Afzal, Anubha Shrivastava, Jyoti Bagla, Sushma Krishnegowda, Ananth Konapur, Azmeri Sultana, Kritika Soni, Nikhil Nair, Divya Sharma, Prajit Khooblall, Avisha Pandey, Khalid Alhasan, Mignon McCulloch, Timothy Bunchman, Abhishek Tibrewal and Rupesh Raina in Peritoneal Dialysis International

Published
2022
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50. Supplemental Material, sj-docx-2-ptd-10.1177_08968608221091023 - Risk factors and outcomes of neonates with acute kidney injury needing peritoneal dialysis: Results from the prospective TINKER (The Indian PCRRT-ICONIC Neonatal Kidney Educational Registry) study

Author

Sethi, Sidharth Kumar, Wazir, Sanjay, Sahoo, Jagdish, Agrawal, Gopal, Bajaj, Naveen, Gupta, Naveen Parkash, Mirgunde, Shishir, Balachandran, Binesh, Afzal, Kamran, Shrivastava, Anubha, Bagla, Jyoti, Krishnegowda, Sushma, Konapur, Ananth, Sultana, Azmeri, Soni, Kritika, Nair, Nikhil, Sharma, Divya, Khooblall, Prajit, Pandey, Avisha, Alhasan, Khalid, McCulloch, Mignon, Bunchman, Timothy, Tibrewal, Abhishek, and Raina, Rupesh

Subjects
Medicine
Abstract

Supplemental Material, sj-docx-2-ptd-10.1177_08968608221091023 for Risk factors and outcomes of neonates with acute kidney injury needing peritoneal dialysis: Results from the prospective TINKER (The Indian PCRRT-ICONIC Neonatal Kidney Educational Registry) study by Sidharth Kumar Sethi, Sanjay Wazir, Jagdish Sahoo, Gopal Agrawal, Naveen Bajaj, Naveen Parkash Gupta, Shishir Mirgunde, Binesh Balachandran, Kamran Afzal, Anubha Shrivastava, Jyoti Bagla, Sushma Krishnegowda, Ananth Konapur, Azmeri Sultana, Kritika Soni, Nikhil Nair, Divya Sharma, Prajit Khooblall, Avisha Pandey, Khalid Alhasan, Mignon McCulloch, Timothy Bunchman, Abhishek Tibrewal and Rupesh Raina in Peritoneal Dialysis International

Published
2022
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