5,112 results on '"Bulgarelli A."'
Search Results
2. Sampling SU(3) pure gauge theory with Stochastic Normalizing Flows
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Bulgarelli, Andrea, Cellini, Elia, and Nada, Alessandro
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High Energy Physics - Lattice - Abstract
Non-equilibrium Monte Carlo simulations based on Jarzynski's equality are a well-understood method to compute differences in free energy and also to sample from a target probability distribution without the need to thermalize the system under study. In each evolution, the system starts from a given base distribution at equilibrium and it is gradually driven out-of-equilibrium while evolving towards the target parameters. If the target distribution suffers from long autocorrelation times, this approach represents a promising candidate to mitigate critical slowing down. Out-of-equilibrium evolutions are conceptually similar to Normalizing Flows and they can be combined into a recently-developed architecture called Stochastic Normalizing Flows (SNFs). In this contribution we first focus on the promising scaling with the volume guaranteed by the purely stochastic approach in the $\mathrm{SU}(3)$ lattice gauge theory in 4 dimensions; then, we define an SNF by introducing gauge-equivariant layers between the out-of-equilibrium Monte Carlo updates, and we analyse the improvement obtained as well as the inherited scaling with the volume. Finally, we discuss how this approach can be systematically improved and how simulations of lattice gauge theories in four dimensions for large volumes and close to criticality can be realistically achieved., Comment: 1+8 pages, 6 figures, contribution for the 41st International Symposium on Lattice Field Theory (Lattice 2024), 28 July - 3 August 2024, Liverpool, UK; v2: 1+9 pages, 6 figures, reference added
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- 2024
3. Towards a response function for the COSI anticoincidence system: preliminary results from Geant4 simulations
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Ciabattoni, Alex, Fioretti, Valentina, Tomsick, John, Zoglauer, Andreas, Jean, Pierre, Franco, Daniel Alvarez, von Ballmoos, Peter, Bulgarelli, Andrea, Vignali, Cristian, Parmiggiani, Nicolò, Panebianco, Gabriele, and Castaldini, Luca
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
The Compton Spectrometer and Imager (COSI) is an upcoming NASA Small Explorer satellite mission scheduled for launch in 2027 and designed to conduct an all-sky survey in the energy range of 0.2-5 MeV. Its instrument consists of an array of germanium detectors surrounded on four sides and underneath by active shields that work as anticoincidence system (ACS) to reduce the contribution of background events in the detectors. These shields are composed of bismuth germanium oxide (BGO), a scintillator material, coupled with Silicon photomultipliers, aimed to collect optical photons produced from interaction of ionizing particles in the BGO and convert them into an electric signal. The reference simulation framework for COSI is MEGAlib, a set of software tools based on the Geant4 toolkit. The interaction point of the incoming radiation, the design of the ACS modules and the BGO surface treatment change the light collection and the overall shielding accuracy. The use of the Geant4 optical physics library, with the simulation of the scintillation process, is mandatory for a more realistic evaluation of the ACS performances. However, including the optical processes in MEGAlib would dramatically increase the computing time of the COSI simulations. We propose the use of a response function encoding the energy resolution and 3D light yield correction based on a separate Geant4 simulation of the ACS that includes the full optical interaction. We present the verification of the Geant4 optical physics library against analytical computations and available laboratory measurements obtained using PMTs as readout device, as a preparatory phase for the simulation of the COSI ACS response., Comment: Proceedings Volume 13093, Space Telescopes and Instrumentation 2024: Ultraviolet to Gamma Ray, Yokohama, Japan
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- 2024
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4. A detailed study of the very-high-energy Crab pulsar emission with the LST-1
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Project, CTA-LST, Abe, K., Abe, S., Abhishek, A., Acero, F., Aguasca-Cabot, A., Agudo, I., Crespo, N. Alvarez, Antonelli, L. A., Aramo, C., Arbet-Engels, A., Arcaro, C., Artero, M., Asano, K., Aubert, P., Baktash, A., Bamba, A., Larriva, A. Baquero, Baroncelli, L., de Almeida, U. Barres, Barrio, J. A., Batkovic, I., Baxter, J., González, J. Becerra, Bernardini, E., Medrano, J. Bernete, Berti, A., Bhattacharjee, P., Bigongiari, C., Bissaldi, E., Blanch, O., Bonnoli, G., Bordas, P., Brunelli, G., Bulgarelli, A., Burelli, I., Burmistrov, L., Buscemi, M., Cardillo, M., Caroff, S., Carosi, A., Carrasco, M. S., Cassol, F., Castrejón, N., Cauz, D., Cerasole, D., Ceribella, G., Chai, Y., Cheng, K., Chiavassa, A., Chikawa, M., Chon, G., Chytka, L., Cicciari, G. M., Cifuentes, A., Contreras, J. L., Cortina, J., Costantini, H., Da Vela, P., Dalchenko, M., Dazzi, F., De Angelis, A., de Lavergne, M. de Bony, De Lotto, B., de Menezes, R., Del Peral, L., Delgado, C., Mengual, J. Delgado, della Volpe, D., Dellaiera, M., Di Piano, A., Di Pierro, F., Di Tria, R., Di Venere, L., Díaz, C., Dominik, R. M., Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Eisenberger, L., Elsässer, D., Emery, G., Escudero, J., Ramazani, V. Fallah, Ferrarotto, F., Fiasson, A., Foffano, L., Coromina, L. Freixas, Fröse, S., Fukazawa, Y., López, R. Garcia, Gasbarra, C., Gasparrini, D., Gavira, L., Geyer, D., Paiva, J. Giesbrecht, Giglietto, N., Giordano, F., Gliwny, P., Godinovic, N., Grau, R., Green, D., Green, J., Gunji, S., Günther, P., Hackfeld, J., Hadasch, D., Hahn, A., Hassan, T., Hayashi, K., Heckmann, L., Heller, M., Llorente, J. Herrera, Hirotani, K., Hoffmann, D., Horns, D., Houles, J., Hrabovsky, M., Hrupec, D., Hui, D., Iarlori, M., Imazawa, R., Inada, T., Inome, Y., Ioka, K., Iori, M., Martinez, I. Jimenez, Quiles, J. Jiménez, Jurysek, J., Kagaya, M., Karas, V., Katagiri, H., Kataoka, J., Kerszberg, D., Kobayashi, Y., Kohri, K., Kong, A., Kubo, H., Kushida, J., Lainez, M., Lamanna, G., Lamastra, A., Lemoigne, L., Linhoff, M., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Lorini, A., Bahilo, J. Lozano, Luque-Escamilla, P. L., Majumdar, P., Makariev, M., Mallamaci, M., Mandat, D., Manganaro, M., Manicò, G., Mannheim, K., Marchesi, S., Mariotti, M., Marquez, P., Marsella, G., Martí, J., Martinez, O., Martínez, G., Martínez, M., Mas-Aguilar, A., Maurin, G., Mazin, D., Guillen, E. Mestre, Micanovic, S., Miceli, D., Miener, T., Miranda, J. M., Mirzoyan, R., Mizuno, T., Gonzalez, M. Molero, Molina, E., Montaruli, T., Moralejo, A., Morcuende, D., Morselli, A., Moya, V., Muraishi, H., Nagataki, S., Nakamori, T., Neronov, A., Nickel, L., Rosillo, M. Nievas, Nikolic, L., Nishijima, K., Noda, K., Nosek, D., Novotny, V., Nozaki, S., Ohishi, M., Ohtani, Y., Oka, T., Okumura, A., Orito, R., Otero-Santos, J., Ottanelli, P., Owen, E., Palatiello, M., Paneque, D., Pantaleo, F. R., Paoletti, R., Paredes, J. M., Pech, M., Pecimotika, M., Peresano, M., Pfeiffle, F., Pietropaolo, E., Pihet, M., Pirola, G., Plard, C., Podobnik, F., Pons, E., Prandini, E., Priyadarshi, C., Prouza, M., Rando, R., Rhode, W., Ribó, M., Righi, C., Rizi, V., Fernandez, G. Rodriguez, Frías, M. D. Rodríguez, Saito, T., Sakurai, S., Sanchez, D. A., Sano, H., Šarić, T., Sato, Y., Saturni, F. G., Savchenko, V., Schiavone, F., Schleicher, B., Schmuckermaier, F., Schubert, J. L., Schussler, F., Schweizer, T., Arroyo, M. Seglar, Siegert, T., Silvia, R., Sitarek, J., Sliusar, V., Strišković, J., Strzys, M., Suda, Y., Tajima, H., Takahashi, H., Takahashi, M., Takata, J., Takeishi, R., Tam, P. H. T., Tanaka, S. J., Tateishi, D., Tavernier, T., Temnikov, P., Terada, Y., Terauchi, K., Terzic, T., Teshima, M., Tluczykont, M., Tokanai, F., Torres, D. F., Travnicek, P., Truzzi, S., Tutone, A., Vacula, M., Vallania, P., van Scherpenberg, J., Acosta, M. Vázquez, Verna, G., Viale, I., Vigliano, A., Vigorito, C. F., Visentin, E., Vitale, V., Voitsekhovskyi, V., Voutsinas, G., Vovk, I., Vuillaume, T., Walter, R., Wan, L., Will, M., Yamamoto, T., Yamazaki, R., Yeung, P. K. H., Yoshida, T., Yoshikoshi, T., Zhang, W., and Zywucka, N.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Context: There are currently three pulsars firmly detected by imaging atmospheric Cherenkov telescopes (IACTs), two of them reaching TeV energies, challenging models of very-high-energy (VHE) emission in pulsars. More precise observations are needed to better characterize pulsar emission at these energies. The LST-1 is the prototype of the Large-Sized Telescope, that will be part of the Cherenkov Telescope Array Observatory (CTAO). Its improved performance over previous IACTs makes it well suited for studying pulsars. Aims: To study the Crab pulsar emission with the LST-1, improving and complementing the results from other telescopes. These observations can also be used to characterize the potential of the LST-1 to study other pulsars and detect new ones. Methods: We analyzed a total of $\sim$103 hours of gamma-ray observations of the Crab pulsar conducted with the LST-1 in the period from September 2020 to January 2023. The observations were carried out at zenith angles less than 50 degrees. A new analysis of the Fermi-LAT data was also performed, including $\sim$14 years of observations. Results: The Crab pulsar phaseogram, long-term light-curve, and phase-resolved spectra are reconstructed with the LST-1 from 20 GeV to 450 GeV for P1 and up to 700 GeV for P2. The pulsed emission is detected with a significance of 15.2$\sigma$. The two characteristic emission peaks of the Crab pulsar are clearly detected (>10$\sigma$), as well as the so-called bridge emission (5.7$\sigma$). We find that both peaks are well described by power laws, with spectral indices of $\sim$3.44 and $\sim$3.03 respectively. The joint analysis of Fermi-LAT and LST-1 data shows a good agreement between both instruments in the overlapping energy range. The detailed results obtained in the first observations of the Crab pulsar with LST-1 show the potential that CTAO will have to study this type of sources., Comment: Accepted by A&A
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- 2024
5. Quantum Convolutional Neural Networks for the detection of Gamma-Ray Bursts in the AGILE space mission data
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Rizzo, A., Parmiggiani, N., Bulgarelli, A., Macaluso, A., Fioretti, V., Castaldini, L., Di Piano, A., Panebianco, G., Pittori, C., Tavani, M., Sartori, C., Burigana, C., Cardone, V., Farsian, F., Meneghetti, M., Murante, G., Scaramella, R., Schillirò, F., Testa, V., and Trombetti, T.
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Astrophysics - High Energy Astrophysical Phenomena ,Computer Science - Artificial Intelligence - Abstract
Quantum computing represents a cutting-edge frontier in artificial intelligence. It makes use of hybrid quantum-classical computation which tries to leverage quantum mechanic principles that allow us to use a different approach to deep learning classification problems. The work presented here falls within the context of the AGILE space mission, launched in 2007 by the Italian Space Agency. We implement different Quantum Convolutional Neural Networks (QCNN) that analyze data acquired by the instruments onboard AGILE to detect Gamma-Ray Bursts from sky maps or light curves. We use several frameworks such as TensorFlow-Quantum, Qiskit and PennyLane to simulate a quantum computer. We achieved an accuracy of 95.1% on sky maps with QCNNs, while the classical counterpart achieved 98.8% on the same data, using however hundreds of thousands more parameters., Comment: 4 pages, 2 figures, proceedings of the ADASS XXXIII (2023) conference, to appear in ASP Conference Serie
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- 2024
6. Deep Learning for AGILE Anticoincidence System's Background Prediction from Orbital and Attitude Parameters
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Parmiggiani, N., Bulgarelli, A., Macaluso, A., Ursi, A., Castaldini, L., Di Piano, A., Falco, R., Fioretti, V., Panebianco, G., Pittori, C., and Tavani, M.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
AGILE is an Italian Space Agency (ASI) space mission launched in 2007 to study X-ray and gamma-ray phenomena in the energy range from $\sim$20 keV to $\sim$10 GeV. The AGILE AntiCoincidence System (ACS) detects hard-X photons in the 50 - 200 keV energy range and continuously stores each panel's count rates in the telemetry. We developed a new Deep Learning (DL) model to predict the background of the AGILE ACS top panel using the satellite's orbital and attitude parameters. This model aims to learn how the orbital and spinning modulations of the satellite impact the background level of the ACS top panel. The DL model executes a regression problem, and is trained with a supervised learning technique on a dataset larger than twenty million orbital parameters' configurations. Using a test dataset, we evaluated the trained model by comparison of the predicted count rates with the real ones. The results show that the model can reconstruct the background count rates of the ACS top panel with an accuracy of 96.7\%, considering the orbital modulation and spinning of the satellite. Starting from these promising results, we are developing an anomaly detection method to detect Gamma-ray Bursts when the differences between predicted and real count rates exceed a predefined threshold., Comment: 4 pages, 2 figure, proceedings of the ADASS XXXIII (2023) conference, to appear in ASP Conference Serie
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- 2024
7. The Online Observation Quality System Implementation for the ASTRI Mini-Array Project
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Castaldini, L., Parmiggiani, N., Bulgarelli, A., Baroncelli, L., Fioretti, V., Di Piano, A., Abu, I., Capalbi, M., Catalano, O., Conforti, V., Fiori, M., Gianotti, F., Lucarelli, F., Maccarone, M. C., Mineo, T., Lombardi, S., Pastore, V., Russo, F., Sangiorgi, P., Scuderi, S., Tosti, G., Trifoglio, M., and Zampieri, L.
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The ASTRI Mini-Array project, led by the Italian National Institute for Astrophysics, aims to construct and operate nine Imaging Atmospheric Cherenkov Telescopes for high-energy gamma-ray source study and stellar intensity interferometry. Located at the Teide Astronomical Observatory in Tenerife, the project's software is essential for remote operation, emphasizing the need for prompt feedback on observations. This contribution introduces the Online Observation Quality System (OOQS) as part of the Supervisory Control And Data Acquisition (SCADA) software. OOQS performs real-time data quality checks on data from Cherenkov cameras and Intensity Interferometry instruments. It provides feedback to SCADA and operators, highlighting abnormal conditions and ensuring quick corrective actions for optimal observations. Results are archived for operator visualization and further analysis. The OOQS data quality pipeline prototype utilizes a distributed application with three main components to handle the maximum array data rate of 1.15 Gb/s. The first is a Kafka consumer that manages the data stream from the Array Data Acquisition System through Apache Kafka, handling the data serialization and deserialization involved in the transmission. The data stream is divided into batches of data written in files. The second component monitors new files and conducts analyses using the Slurm workload scheduler, leveraging its parallel processing capabilities and scalability. Finally, the process results are collected by the last component and stored in the Quality Archive., Comment: 4 pages, 2 figures, proceedings of the Astronomical Data Analysis Software & Systems XXXIII (ADASS 2023) conference, to appear in ASP Conference Serie
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- 2024
8. Duality transformations and the entanglement entropy of gauge theories
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Bulgarelli, Andrea and Panero, Marco
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Quantum Physics ,Condensed Matter - Statistical Mechanics ,High Energy Physics - Lattice ,High Energy Physics - Theory - Abstract
The study of entanglement in gauge theories is expected to provide insights into many fundamental phenomena, including confinement. However, calculations of quantities related to entanglement in gauge theories are limited by ambiguities that stem from the non-factorizability of the Hilbert space. In this work we study lattice gauge theories that admit a dual description in terms of spin models, for which the replica trick and R\'enyi entropies are well defined. In the first part of this work, we explicitly perform the duality transformation in a replica geometry, deriving the structure of a replica space for a gauge theory. Then, in the second part, we calculate, by means of Monte Carlo simulations, the entropic c-function of the $\Z_2$ gauge theory in three spacetime dimensions, exploiting its dual description in terms of the three-dimensional Ising model., Comment: 23+18 pages; v2: added references, matches pubished version
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- 2024
- Full Text
- View/download PDF
9. Theoretical and numerical comparison between the pseudopotential and the free energy lattice Boltzmann methods
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Czelusniak, L. E., Martins, I. T., Cabezas-Gómez, L., Bulgarelli, N. A. V., Verde, W. Monte, and de Castro, M. S.
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Physics - Computational Physics - Abstract
The pseudopotential and free energy models are two popular extensions of the lattice Boltzmann method for multiphase flows. Until now, they have been developed apart from each other in the literature. However, important questions about whether each method performs better needs to be solved. In this work, we perform a theoretical and numerical comparison between both methods. This comparison is only possible because we developed a novel approach for controlling the interface thickness in the pseudopotential method independently on the equation of state. In this way, it is possible to compare both methods maintaining the same equilibrium densities, interface thickness, surface tension and equation of state parameters. The well-balanced approach was selected to represent the free energy. We found that the free energy one is more practical to use, as it is not necessary to carry out previous simulations to determine simulation parameters (interface thickness, surface tension, etc). In addition, the tests proofed that the free energy model is more accurate than the pseudopotential model. Furthermore, the pseudopotential method suffers from a lack of thermodynamic consistency even when applying the corrections proposed in the literature. On the other hand, for both static and dynamic tests we verified that the pseudopotential method is more stable than the free energy one, allowing simulations with lower reduced temperatures. We hope that these results will guide authors in the use of each method., Comment: 20 pages, 9 figures
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- 2024
10. Dark Matter Line Searches with the Cherenkov Telescope Array
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Abe, S., Abhir, J., Abhishek, A., Acero, F., Acharyya, A., Adam, R., Aguasca-Cabot, A., Agudo, I., Aguirre-Santaella, A., Alfaro, J., Alfaro, R., Alvarez-Crespo, N., Batista, R. Alves, Amans, J. -P., Amato, E., Ambrosi, G., Angel, L., Aramo, C., Arcaro, C., Arnesen, T. T. H., Arrabito, L., Asano, K., Ascasibar, Y., Aschersleben, J., Ashkar, H., Backes, M., Baktash, A., Balazs, C., Balbo, M., Larriva, A. Baquero, Martins, V. Barbosa, de Almeida, U. Barres, Barrio, J. A., Batković, I., Batzofin, R., Baxter, J., González, J. Becerra, Beck, G., Benbow, W., Berge, D., Bernardini, E., Bernete, J., Bernlöhr, K., Berti, A., Bertucci, B., Bhattacharjee, P., Bhattacharyya, S., Bigongiari, C., Biland, A., Bissaldi, E., Biteau, J., Blanch, O., Blazek, J., Bocchino, F., Boisson, C., Bolmont, J., Bonnoli, G., Bonollo, A., Bordas, P., Bosnjak, Z., Bottacini, E., Böttcher, M., Bringmann, T., Bronzini, E., Brose, R., Brown, A. M., Brunelli, G., Bulgarelli, A., Bulik, T., Burelli, I., Burmistrov, L., Burton, M., Buscemi, M., Bylund, T., Cailleux, J., Campoy-Ordaz, A., Cantlay, B. K., Capasso, G., Caproni, A., Capuzzo-Dolcetta, R., Caraveo, P., Caroff, S., Carosi, A., Carosi, R., Carquin, E., Carrasco, M. -S., Cassol, F., Castaldini, L., Castrejon, N., Castro-Tirado, A. J., Cerasole, D., Cerruti, M., Chadwick, P. M., Chaty, S., Chen, A. W., Chernyakova, M., Chiavassa, A., Chudoba, J., Chytka, L., Cicciari, G. M., Cifuentes, A., Araujo, C. H. Coimbra, Colapietro, M., Conforti, V., Conte, F., Contreras, J. L., Costa, A., Costantini, H., Cotter, G., Cristofari, P., Cuevas, O., Curtis-Ginsberg, Z., D'Amico, G., D'Ammando, F., Dai, S., Dalchenko, M., Dazzi, F., De Angelis, A., de Lavergne, M. de Bony, De Caprio, V., Pino, E. M. de Gouveia Dal, De Lotto, B., De Lucia, M., de Menezes, R., de Naurois, M., de Souza, V., del Peral, L., del Valle, M. V., Giler, A. G. Delgado, Mengual, J. Delgado, Delgado, C., Dell'aiera, M., della Volpe, D., Depaoli, D., Di Girolamo, T., Di Piano, A., Di Pierro, F., Di Tria, R., Di Venere, L., Díaz, C., Diebold, S., Dinesh, A., Djuvsland, J., Dominik, R. M., Prester, D. Dominis, Donini, A., Dorner, D., Dörner, J., Doro, M., Dournaux, J. -L., Duangchan, C., Dubos, C., Ducci, L., Dwarkadas, V. V., Ebr, J., Eckner, C., Egberts, K., Einecke, S., Elsässer, D., Emery, G., Errando, M., Escanuela, C., Escarate, P., Godoy, M. Escobar, Escudero, J., Esposito, P., Ettori, S., Falceta-Goncalves, D., Fedorova, E., Fegan, S., Feng, Q., Ferrand, G., Ferrarotto, F., Fiandrini, E., Fiasson, A., Filipovic, M., Fioretti, V., Fiori, M., Foffano, L., Guiteras, L. Font, Fontaine, G., Fröse, S., Fukazawa, Y., Fukui, Y., Furniss, A., Galanti, G., Galaz, G., Galelli, C., Gallozzi, S., Gammaldi, V., Garczarczyk, M., Gasbarra, C., Gasparrini, D., Ghalumyan, A., Gianotti, F., Giarrusso, M., Paiva, J. G. Giesbrecht Formiga, Giglietto, N., Giordano, F., Giuffrida, R., Glicenstein, J. -F., Glombitza, J., Goldoni, P., González, J. M., González, M. M., Coelho, J. Goulart, Gradetzke, T., Granot, J., Grasso, D., Grau, R., Gréaux, L., Green, D., Green, J. G., Grolleron, G., Guedes, L. M. V., Gueta, O., Hackfeld, J., Hadasch, D., Hamal, P., Hanlon, W., Hara, S., Harvey, V. M., Hassan, T., Hayashi, K., Heß, B., Heckmann, L., Heller, M., Cadena, S. Hernández, Hervet, O., Hinton, J., Hiroshima, N., Hnatyk, B., Hnatyk, R., Hofmann, W., Holder, J., Horan, D., Horvath, P., Hovatta, T., Hrabovsky, M., Hrupec, D., Iarlori, M., Inada, T., Incardona, F., Inoue, S., Inoue, Y., Iocco, F., Iori, M., Ishio, K., Jamrozy, M., Janecek, P., Jankowsky, F., Jean, P., Quiles, J. Jimenez, Jin, W., Juramy-Gilles, C., Jurysek, J., Kagaya, M., Kalekin, O., Karas, V., Katagiri, H., Kataoka, J., Kaufmann, S., Kazanas, D., Kerszberg, D., Kieda, D. B., Kleiner, T., Kluge, G., Kobayashi, Y., Kohri, K., Komin, N., Kornecki, P., Kosack, K., Kowal, G., Kubo, H., Kushida, J., La Barbera, A., La Palombara, N., Láinez, M., Lamastra, A., Lapington, J., Laporte, P., Lazarević, S., Lazendic-Galloway, J., Lemoine-Goumard, M., Lenain, J. -P., Leone, F., Leonora, E., Leto, G., Lindfors, E., Linhoff, M., Liodakis, I., Lipniacka, A., Lombardi, S., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Bahilo, J. Lozano, Luque-Escamilla, P. L., Macias, O., Majumdar, P., Mallamaci, M., Malyshev, D., Mandat, D., Manicò, G., Mariotti, M., Márquez, I., Marquez, P., Marsella, G., Martí, J., Martínez, G. A., Martínez, M., Martinez, O., Marty, C., Mas-Aguilar, A., Mastropietro, M., Mazin, D., Menchiari, S., Mestre, E., Meunier, J. -L., Meyer, D. M. -A., Meyer, M., Miceli, D., Miceli, M., Michailidis, M., Michałowski, J., Miener, T., Miranda, J. M., Mitchell, A., Mizote, M., Mizuno, T., Moderski, R., Molero, M., Molfese, C., Molina, E., Montaruli, T., Moralejo, A., Morcuende, D., Morselli, A., Moulin, E., Zamanillo, V. Moya, Munari, K., Murach, T., Muraczewski, A., Muraishi, H., Nakamori, T., Nayak, A., Nemmen, R., Neto, J. P., Nickel, L., Niemiec, J., Nieto, D., Rosillo, M. Nievas, Nikołajuk, M., Nikolić, L., Nishijima, K., Noda, K., Nosek, D., Novotny, V., Nozaki, S., Ohishi, M., Ohtani, Y., Okumura, A., Olive, J. -F., Ong, R. A., Orienti, M., Orito, R., Orlandini, M., Orlando, E., Orlando, S., Ostrowski, M., Otero-Santos, J., Oya, I., Pagano, I., Pagliaro, A., Palatiello, M., Panebianco, G., Paneque, D., Pantaleo, F. R., Paredes, J. M., Parmiggiani, N., Patricelli, B., Pe'er, A., Pech, M., Pecimotika, M., Pensec, U., Peresano, M., Pérez-Romero, J., Persic, M., Peters, K. P., Petruk, O., Piano, G., Pierre, E., Pietropaolo, E., Pihet, M., Pinchbeck, L., Pirola, G., Pittori, C., Plard, C., Podobnik, F., Pohl, M., Pollet, V., Ponti, G., Prandini, E., Principe, G., Priyadarshi, C., Produit, N., Prouza, M., Pueschel, E., Pühlhofer, G., Pumo, M. L., Queiroz, F., Quirrenbach, A., Rainò, S., Rando, R., Razzaque, S., Regeard, M., Reimer, A., Reimer, O., Reisenegger, A., Rhode, W., Ribeiro, D., Ribó, M., Ricci, C., Richtler, T., Rico, J., Rieger, F., Riitano, L., Rizi, V., Roache, E., Fernandez, G. Rodriguez, Frías, M. D. Rodríguez, Rodríguez-Vázquez, J. J., Romano, P., Romeo, G., Rosado, J., de Leon, A. Rosales, Rowell, G., Rudak, B., Ruiter, A. J., Rulten, C. B., Sadeh, I., Saha, L., Saito, T., Salzmann, H., Sánchez-Conde, M., Sandaker, H., Sangiorgi, P., Sano, H., Santander, M., Santos-Lima, R., Sapienza, V., Šarić, T., Sarkar, A., Sarkar, S., Saturni, F. G., Savarese, S., Scherer, A., Schiavone, F., Schipani, P., Schleicher, B., Schovanek, P., Schubert, J. L., Schwanke, U., Arroyo, M. Seglar, Seitenzahl, I. R., Sergijenko, O., Servillat, M., Siegert, T., Siejkowski, H., Siqueira, C., Sliusar, V., Slowikowska, A., Sol, H., Spencer, S. T., Spiga, D., Stamerra, A., Stanič, S., Starecki, T., Starling, R., Stawarz, Ł., Steppa, C., Hatlen, E. Sæther, Stolarczyk, T., Strišković, J., Suda, Y., Świerk, P., Tajima, H., Tak, D., Takahashi, M., Takeishi, R., Tavernier, T., Tejedor, L. A., Terauchi, K., Teshima, M., Testa, V., Tian, W. W., Tibaldo, L., Tibolla, O., Peixoto, C. J. Todero, Torradeflot, F., Torres, D. F., Tosti, G., Tothill, N., Toussenel, F., Tramacere, A., Travnicek, P., Tripodo, G., Trois, A., Truzzi, S., Tutone, A., Vaclavek, L., Vacula, M., Vallania, P., Vallés, R., van Eldik, C., van Scherpenberg, J., Vandenbroucke, J., Vassiliev, V., Acosta, M. Vázquez, Vecchi, M., Ventura, S., Vercellone, S., Verna, G., Viana, A., Viaux, N., Vigliano, A., Vignatti, J., Vigorito, C. F., Villanueva, J., Visentin, E., Vitale, V., Vodeb, V., Voisin, V., Voitsekhovskyi, V., Vorobiov, S., Voutsinas, G., Vovk, I., Vuillaume, T., Wagner, S. J., Walter, R., White, M., White, R., Wierzcholska, A., Will, M., Williams, D. A., Wohlleben, F., Wolter, A., Yamamoto, T., Yang, L., Yoshida, T., Yoshikoshi, T., Zaharijas, G., Zampieri, L., Sanchez, R. Zanmar, Zavrtanik, D., Zavrtanik, M., Zdziarski, A. A., Zech, A., Zhang, W., Zhdanov, V. I., Ziętara, K., Živec, M., and Zuriaga-Puig, J.
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High Energy Physics - Phenomenology ,Astrophysics - High Energy Astrophysical Phenomena ,High Energy Physics - Experiment - Abstract
Monochromatic gamma-ray signals constitute a potential smoking gun signature for annihilating or decaying dark matter particles that could relatively easily be distinguished from astrophysical or instrumental backgrounds. We provide an updated assessment of the sensitivity of the Cherenkov Telescope Array (CTA) to such signals, based on observations of the Galactic centre region as well as of selected dwarf spheroidal galaxies. We find that current limits and detection prospects for dark matter masses above 300 GeV will be significantly improved, by up to an order of magnitude in the multi-TeV range. This demonstrates that CTA will set a new standard for gamma-ray astronomy also in this respect, as the world's largest and most sensitive high-energy gamma-ray observatory, in particular due to its exquisite energy resolution at TeV energies and the adopted observational strategy focussing on regions with large dark matter densities. Throughout our analysis, we use up-to-date instrument response functions, and we thoroughly model the effect of instrumental systematic uncertainties in our statistical treatment. We further present results for other potential signatures with sharp spectral features, e.g.~box-shaped spectra, that would likewise very clearly point to a particle dark matter origin., Comment: 44 pages JCAP style (excluding author list and references), 19 figures; minor changes to match published version
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- 2024
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11. Multi-wavelength observations of the lensed quasar PKS 1830$-$211 during the 2019 $\gamma$-ray flare
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Vercellone, S., Donnarumma, I., Pittori, C., Capitanio, F., De Rosa, A., Di Gesu, L., Kiehlmann, S., Iacolina, M. N., Pellizzoni, P. A., Egron, E., Pacciani, L., Piano, G., Puccetti, S., Righini, S., Valente, G., Verrecchia, F., Vittorini, V., Tavani, M., Brocato, E., Chen, A. W., Hovatta, T., Melis, A., Max-Moerbeck, W., Perrodin, D., Pilia, M., Pili, M., Readhead, A. C. S., Reeves, R., Ridolfi, A., Vitali, F., Bulgarelli, A., Cattaneo, P. W., Lucarelli, F., Morselli, A., and Trois, A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
PKS 1830$-$211 is a $\gamma$-ray emitting, high-redshift (z $= 2.507 \pm 0.002$), lensed flat-spectrum radio quasar. During the period mid-February to mid-April 2019, this source underwent a series of strong $\gamma$-ray flares that were detected by both AGILE-GRID and Fermi-LAT, reaching a maximum $\gamma$-ray flux of $F_{\rm E>100 MeV}\approx 2.3\times10^{-5}$ ph cm$^{-2}$ s$^{-1}$. Here we report on a coordinated campaign from both on-ground (Medicina, OVRO, REM, SRT) and orbiting facilities (AGILE, Fermi, INTEGRAL, NuSTAR, Swift, Chandra), with the aim of investigating the multi-wavelength properties of PKS 1830$-$211 through nearly simultaneous observations presented here for the first time. We find a possible break in the radio spectra in different epochs above 15 GHz, and a clear maximum of the 15 GHz data approximately 110 days after the $\gamma$-ray main activity periods. The spectral energy distribution shows a very pronounced Compton dominance (> 200) which challenges the canonical one-component emission model. Therefore we propose that the cooled electrons of the first component are re-accelerated to a second component by, e.g., kink or tearing instability during the $\gamma$-ray flaring periods. We also note that PKS 1830$-$211 could be a promising candidate for future observations with both Compton satellites (e.g., e-ASTROGAM) and Cherenkov arrays (CTAO) which will help, thanks to their improved sensitivity, in extending the data availability in energy bands currently uncovered., Comment: Accepted for publication in MNRAS. 16 pages, 18 figures, 12 tables
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- 2023
12. Bottom-up perspective – The role of roots and rhizosphere in climate change adaptation and mitigation in agroecosystems
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George, T. S., Bulgarelli, D., Carminati, A., Chen, Y., Jones, D., Kuzyakov, Y., Schnepf, A., Wissuwa, M., and Roose, T.
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- 2024
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13. Eucalypt seedlings lack a clear phosphate starvation response under low phosphorus availability
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Bulgarelli, Rafaela Gageti, Araujo, Pedro, Engel, Eduardo, Mazzafera, Paulo, and de Andrade, Sara Adrián López
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- 2024
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14. Chasing Gravitational Waves with the Cherenkov Telescope Array
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Green, Jarred Gershon, Carosi, Alessandro, Nava, Lara, Patricelli, Barbara, Schüssler, Fabian, Seglar-Arroyo, Monica, Consortium, Cta, Abe, Kazuki, Abe, Shotaro, Acharyya, Atreya, Adam, Remi, Aguasca-Cabot, Arnau, Agudo, Ivan, Alfaro, Jorge, Alvarez-Crespo, Nuria, Batista, Rafael Alves, Amans, Jean-Philippe, Amato, Elena, Ambrosino, Filippo, Angüner, Ekrem Oguzhan, Antonelli, Lucio Angelo, Aramo, Carla, Arcaro, Cornelia, Arrabito, Luisa, Asano, Katsuaki, Aschersleben, Jann, Ashkar, Halim, Stuani, Luiz Augusto, Baack, Dominik, Backes, Michael, Balazs, Csaba, Balbo, Matteo, Larriva, Andres Baquero, Martins, Victor Barbosa, de Almeida, Ulisses Barres, Barrio, Juan Abel, Bastieri, Denis, Batista, Pedro Ivo, Batković, Ivana, Batzofin, Rowan William, Baxter, Joshua Ryo, Beck, Geoffrey, Tjus, Julia Becker, Beiske, Lukas, Belardinelli, Daniele, Benbow, Wystan, Bernardini, Elisa, Medrano, Juan Bernete, Bernlöhr, Konrad, Berti, Alessio, Beshley, Vasyl, Bhattacharjee, Pooja, Bhattacharyya, Saptashwa, Bi, Baiyang, Biederbeck, Noah, Biland, Adrian, Bissaldi, Elisabetta, Blanch, Oscar, Blazek, Jiri, Boisson, Catherine, Bolmont, Julien, Bonnoli, Giacomo, Bordas, Pol, Bošnjak, Željka, Bradascio, Federica, Braiding, Catherine, Bronzini, Ettore, Brose, Robert, Brown, Anthony M., Brun, Francois, Brunelli, Giulia, Bulgarelli, Andrea, Burelli, Irene, Burmistrov, Leonid, Burton, Michael, Bylund, Tomas, Calisse, Paolo Gherardo, Campoy-Ordaz, Anna, Cantlay, Brandon Khan, Capalbi, Milvia, Caproni, Anderson, Capuzzo-Dolcetta, Roberto, Carlile, Colin, Caroff, Sami, Carosi, Roberto, Carrasco, Marie-Sophie, Cascone, Enrico, Cassol, Franca, Castrejon, Noelia, Catalani, Fernando, Cerasole, Davide, Cerruti, Matteo, Chaty, Sylvain, Chen, Andrew W, Chernyakova, Maria, Chiavassa, Andrea, Chudoba, Jiří, Araujo, Carlos Henrique Coimbra, Conforti, Vito, Conte, Francesco, Contreras, Jose Luis, Cossou, Christophe, Costa, Alessandro, Costantini, Heide, Cristofari, Pierre, Cuevas, Omar, Curtis-Ginsberg, Zachary, D'Amico, Giacomo, D'Ammando, Filippo, Dadina, Mauro, Dalchenko, Mykhailo, David, Ludovic, Davids, Isak Delberth, Dazzi, Francesco, De Angelis, Alessandro, de Lavergne, Mathieu de Bony, De Caprio, Vincenzo, De Cesare, Giovanni, Pino, Elisabete M. de Gouveia Dal, De Lotto, Barbara, de Lucia, Mario, de Menezes, Raniere, de Naurois, Mathieu, Wilhelmi, Emma de Oña, De Simone, Nicola, de Souza, Vitor, Del Peral, Luis, del Valle, Maria Victoria, Delagnes, Eric, Giler, Andres Gabriel Delgado, Delgado, Carlos, Dell'aiera, Michael, Della Ceca, Roberto, Della Valle, Massimo, Della Volpe, Domenico, Depaoli, Davide, Dettlaff, Antonios, Di Girolamo, Tristano, Di Piano, Ambra, Di Pierro, Federico, Di Tria, Riccardo, Di Venere, Leonardo, Díaz-Bahamondes, Christian, Dib, Claudio, Diebold, Sebastian, Dima, Razvan, Dinesh, Adithiya, Djannati-Ataï, Arache, Djuvsland, Julia Isabel, Dominguez, Alberto, Dominik, Rune Michael, Donini, Alice, Dorner, Daniela, Dörner, Julien, Doro, Michele, Anjos, Rita de Cassia dos, Dournaux, Jean-Laurent, Dravins, Dainis, Duangchan, Chaimongkol, Dubos, Coline, Ducci, Lozenzo, Dwarkadas, Vikram V., Ebr, Jan, Eckner, Christopher, Egberts, Kathrin, Einecke, Sabrina, Elsässer, Dominik, Emery, Gabriel, Godoy, Miguel Escobar, Escudero, Juan, Esposito, Paolo, Falceta-Gonçalves, Diego, Ramazani, Vandad Fallah, Faure, Alice, Fedorova, Elena, Fegan, Stephen, Feijen, Kirsty, Feng, Qi, Ferrand, Gilles, Ferrarotto, Fabio, Fiandrini, Emanuele, Fiasson, Armand, Fioretti, Valentina, Foffano, Luca, Guiteras, Lluis Font, Fontaine, Gerard, Fröse, Stefan, Fukami, Satoshi, Fukui, Yasuo, Funk, Stefan, Gaggero, Daniele, Galanti, Giorgio, Galaz, Gaspar, Gallant, Yves A., Gallozzi, Stefano, Gammaldi, Viviana, Gasbarra, Claudio, Gaug, Markus, Ghalumyan, Arsen, Gianotti, Fulvio, Giarrusso, Marina, Giglietto, Nicola, Giordano, Francesco, Giuliani, Andrea, Glicenstein, Jean-Francois, Glombitza, Jonas, Goldoni, Paolo, González, José Mauricio, González, Maria Magdalena, Coelho, Jaziel Goulart, Granot, Jonathan, Grasso, Dario, Haro, Roger Grau, Green, David, Greenshaw, Tim, Grolleron, Guillaume, Grube, Jeff, Gueta, Orel, Gunji, Shuichi, Hadasch, Daniela, Hamal, Petr, Hanlon, William, Hara, Satoshi, Harvey, Violet M., Hashiyama, Kazuaki, Hassan, Tarek, Heller, Matthieu, Cadena, Sergio Hernández, Hie, Jonathan, Hiroshima, Nagisa, Hnatyk, Bohdan, Hnatyk, Roman, Hoffmann, Dirk, Hofmann, Werner, Holler, Markus, Horan, Deirdre, Horvath, Pavel, Hovatta, Talvikki, Hrupec, Dario, Hussain, Saqib, Iarlori, Marco, Inada, Tomohiro, Incardona, Federico, Inome, Yusuke, Inoue, Susumu, Iocco, Fabio, Ishio, Kazuma, Jamrozy, Marek, Janecek, Petr, Jankowsky, Felix, Jarnot, Christian, Jean, Pierre, Martínez, Irene Jiménez, Jin, Weidong, Jocou, Laurent, Juramy-Gilles, Claire, Jurysek, Jakub, KALEKIN, Oleg, Kantzas, Dimitrios, Karas, Vladimir, Kaufmann, Sarah, Kerszberg, Daniel, Khelifi, Bruno, Kieda, David B, Kleiner, Tobias Kai, Kluźniak, Włodzimierz, Kobayashi, Yukiho, Kohri, Kazunori, Komin, Nukri, Kornecki, Paula, Kosack, Karl, Kubo, Hidetoshi, Kushida, Junko, La Barbera, Antonino, La Palombara, Nicola, Lainez, Maria, Lamastra, Alessandra, Lapington, Jon S, Lazarevic, Sanja, Lazendic-Galloway, Jasmina, Leach, Steven, Lemoine-Goumard, Marianne, Lenain, Jean-Philippe, Leto, Giuseppe, Leuschner, Fabian, Lindfors, Elina, Linhoff, Maximilian, Liodakis, Ioannis, Loïc, Lozach, Lombardi, Saverio, Longo, Francesco, López-Coto, Rubén, López-Moya, Marcos, López-Oramas, Alicia, Loporchio, Serena, Bahilo, Julio Lozano, Luque-Escamilla, Pedro L., Macias, Oscar, Maier, Gernot, Majumdar, Pratik, Malyshev, Denys, Malyshev, Dmitry, Mandat, Dusan, Manicò, Giulio, Marinos, Peter David, Markoff, Sera, Márquez, Isabel, Marquez, Patricia, Marsella, Giovanni, Martí, Josep, Martin, Pierrick, Martínez, Gustavo Augusto, Martínez, Manel, Martinez, Oibar, Marty, Christophe, Mas-Aguilar, Alvaro, Mastropietro, Michele, Maurin, Gilles, Max-Moerbeck, Walter, Mazin, Daniel, Melkumyan, David, Menchiari, Stefano, Mestre, Enrique, Meunier, Jean-Luc, Meyer, Dominique M. -A., Miceli, Davide, Michailidis, Miltiadis, Michałowski, Jerzy, Miener, Tjark, Miranda, Jose Miguel, Mitchell, Alison, Mizote, Masaya, Mizuno, Tsunefumi, Moderski, Rafal, Mohrmann, Lars, Molero, Miguel, Molfese, Cesare, Molina, Edgar, Montaruli, Teresa, Moralejo, Abelardo, Morcuende, Daniel, Morik, Katharina, Morselli, Aldo, Moulin, Emmanuel, Zamanillo, Victor Moya, Mukherjee, Reshmi, Munari, Kevin, Muraczewski, Adam, Muraishi, Hiroshi, Nakamori, Takeshi, Nayak, Amrit, Nemmen, Rodrigo, Nickel, Lukas, Niemiec, Jacek, Nieto, Daniel, Rosillo, Mireia Nievas, Nikołajuk, Marek, Nishijima, Kyoshi, Noda, Koji, Nosek, Dalibor, Novosyadlyj, Bohdan, Novotný, Vladimír, Nozaki, Seiya, O'Brien, Paul, Ohishi, Michiko, Ohtani, Yoshiki, Okumura, Akira, Olive, Jean-François, Olmi, Barbara, Ong, Rene A., Orienti, Monica, Orito, Reiko, Orlandini, Mauro, Orlando, Elena, Ostrowski, Michal, Otte, Nepomuk, Oya, Igor, Pagano, Isabella, Pagliaro, Antonio, Palatiello, Michele, Panebianco, Gabriele, Paredes, Josep M., Parmiggiani, Nicolò, Patel, Sonal Ramesh, Pavlović, Dijana, Pe'er, Asaf, Pech, Miroslav, Pecimotika, Mario, Peresano, Michele, Pérez-Romero, Judit, Peron, Giada, Persic, Massimo, Petrucci, Pierre-Olivier, Petruk, Oleh, Pfeifle, Felix, Pintore, Fabio, Pirola, Giorgio, Pittori, Carlotta, Plard, Cyann, Podobnik, Franjo, Pohl, Martin, Pons, Estelle, Prandini, Elisa, Prast, Julie, Principe, Giacomo, Priyadarshi, Chaitanya, Produit, Nicolas, Prokhorov, Dmitry, Pueschel, Elisa, Pühlhofer, Gerd, Pumo, Maria Letizia, Punch, Michael, Quirrenbach, Andreas, Raino, Silvia, Randazzo, Nunzio, Rando, Riccardo, Ravel, Thierry, Razzaque, Soebur, Regeard, Maxime, Reichherzer, Patrick, Reimer, Anita, Reimer, Olaf, Reisenegger, Andreas, Reposeur, Thierry, Reville, Brian, Rhode, Wolfgang, Ribó, Marc, Richtler, Tom, Rieger, Frank, Roache, Emmet, Fernandez, Gonzalo Rodriguez, Frías, Maria Dolores Rodríguez, Rodríguez-Vázquez, Juan José, Romano, Patrizia, Romeo, Giuseppe, Rosado, Jaime, Rowell, Gavin P, Rudak, Bronislaw, Ruiter, Ashley J., Rulten, Cameron Boyd, Russo, Federico, Sadeh, Iftach, Saha, Lab, Saito, Takayuki, Sakurai, Shunsuke, Salzmann, Heiko, Sanchez, David, Sanchez-Conde, Miguel, Sangiorgi, Pierluca, Sano, Hidetoshi, Santander, Marcos, Santangelo, Andrea, Santos-Lima, Reinaldo, Sanuy, Andreu, Šarić, Toni, Sarkar, Arkadipta, Sarkar, Subir, Saturni, Francesco Gabriele, Savchenko, Volodymyr, Scherer, Andres, Schipani, Pietro, Schleicher, Bernd, Schovanek, Petr, Schubert, Jan Lukas, Schwanke, Ullrich, Schwefer, Georg, Scuderi, Salvatore, Arroyo, Monica Seglar, Seitenzahl, Ivo, Sergijenko, Olga, Sguera, Vito, Shang, Ruo-Yu, Sharma, Pooja, Sidibe, Guereguin Der Sylvestre, Sidoli, Lara, Siejkowski, Hubert, Siqueira, Clarissa, Sizun, Patrick, Sliusar, Vitalii, Slowikowska, Agnieszka, Sol, Helene, Specovius, Andreas, Spencer, Samuel Timothy, Spiga, Daniele, Stamerra, Antonio, Stanič, Samo, Starecki, Tomasz, Starling, Rhaana, Steppa, Constantin, Stolarczyk, Thierry, Strišković, Jelena, Strzys, Marcel C., Suda, Yusuke, Suomijarvi, Tiina, Tak, Donggeun, Takahashi, Mitsunari, Takeishi, Ryuji, Tam, Pak-Hin Thomas, Tanaka, Shuta J, Tanaka, Takaaki, Terauchi, Kenta, Testa, Vincenzo, Tibaldo, Luigi, Tibolla, Omar, Torradeflot, Francesc, Torres, Diego F., Torresi, Eleonora, Tothill, Nick, Toussenel, Francois, Touzard, Victoria, Tramacere, Andrea, Travnicek, Petr, Tripodo, Giovanni, Truzzi, Stefano, Tsiahina, Adellain, Tutone, Antonio, Vacula, Martin, Vallage, Bertrand, Vallania, Piero, Vallés, Ramon, van Eldik, Christopher, van Scherpenberg, Juliane, Vandenbroucke, Justin, Vassiliev, Vladimir, Venault, Philippe, Ventura, Sofia, Vercellone, Stefano, Verna, Gaia, Viana, Aion, Viaux, Nicolás, Vigliano, Alessandro, Vignatti, Jonatan, Vigorito, Carlo francesco, Vitale, Vincenzo, Vodeb, Veronika, Voisin, Vincent, Vorobiov, Serguei, Voutsinas, Georgios Gerasimos, Vovk, Ievgen, Waegebaert, Vincent, Wagner, Stefan Joachim, Walter, Roland, Ward, Martin, Wechakama, Maneenate, White, Richard, Wierzcholska, Alicja, Will, Martin, Williams, David A., Wohlleben, Frederik, Wolter, Anna, Yamamoto, Tokonatsu, Yamazaki, Ryo, Yang, Lili, Yoshida, Tatsuo, Yoshikoshi, Takanori, Zacharias, Michael, Sanchez, Ricardo Zanmar, Zavrtanik, Danilo, Zavrtanik, Marko, Zdziarski, Andrzej A., Zech, Andreas, Zhdanov, Valery I., Ziȩtara, Krzysztof, Živec, Miha, and Zuriaga-Puig, Jaume
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The detection of gravitational waves from a binary neutron star merger by Advanced LIGO and Advanced Virgo (GW170817), along with the discovery of the electromagnetic counterparts of this gravitational wave event, ushered in a new era of multimessenger astronomy, providing the first direct evidence that BNS mergers are progenitors of short gamma-ray bursts (GRBs). Such events may also produce very-high-energy (VHE, > 100GeV) photons which have yet to be detected in coincidence with a gravitational wave signal. The Cherenkov Telescope Array (CTA) is a next-generation VHE observatory which aims to be indispensable in this search, with an unparalleled sensitivity and ability to slew anywhere on the sky within a few tens of seconds. New observing modes and follow-up strategies are being developed for CTA to rapidly cover localization areas of gravitational wave events that are typically larger than the CTA field of view. This work will evaluate and provide estimations on the expected number of of gravitational wave events that will be observable with CTA, considering both on- and off-axis emission. In addition, we will present and discuss the prospects of potential follow-up strategies with CTA., Comment: Presented at the 38th International Cosmic Ray Conference (ICRC 2023), 2023 (arXiv:2309.08219)
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- 2023
15. Performance of the joint LST-1 and MAGIC observations evaluated with Crab Nebula data
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Abe, H., Abe, K., Abe, S., Acciari, V. A., Aguasca-Cabot, A., Agudo, I., Crespo, N. Alvarez, Aniello, T., Ansoldi, S., Antonelli, L. A., Aramo, C., Arbet-Engels, A., Arcaro, C., Artero, M., Asano, K., Aubert, P., Baack, D., Babić, A., Baktash, A., Bamba, A., Larriva, A. Baquero, Baroncelli, L., de Almeida, U. Barres, Barrio, J. A., Batković, I., Baxter, J., González, J. Becerra, Bednarek, W., Bernardini, E., Bernardos, M. I., Medrano, J. Bernete, Berti, A., Besenrieder, J., Bhattacharjee, P., Biederbeck, N., Bigongiari, C., Biland, A., Bissaldi, E., Blanch, O., Bonnoli, G., Bordas, P., Bošnjak, Ž., Bulgarelli, A., Burelli, I., Burmistrov, L., Buscemi, M., Busetto, G., Ordaz, A. Campoy, Cardillo, M., Caroff, S., Carosi, A., Carosi, R., Carrasco, M. S., Carretero-Castrillo, M., Cassol, F., Castro-Tirado, A. J., Cauz, D., Cerasole, D., Ceribella, G., Chai, Y., Cheng, K., Chiavassa, A., Chikawa, M., Chytka, L., Cifuentes, A., Cikota, S., Colombo, E., Contreras, J. L., Cornelia, A., Cortina, J., Costantini, H., Covino, S., D'Amico, G., D'Elia, V., Da Vela, P., Dalchenko, M., Dazzi, F., De Angelis, A., de Lavergne, M. de Bony, De Lotto, B., De Lucia, M., de Menezes, R., Del Peral, L., Del Popolo, A., Deleglise, G., Delfino, M., Mendez, C. Delgado, Mengual, J. Delgado, della Volpe, D., Dellaiera, M., Depaoli, D., Di Piano, A., Di Pierro, F., Di Pilato, A., Di Tria, R., Di Venere, L., Dominik, R. M., Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Díaz, C., Eisenberger, L., Elsässer, D., Emery, G., Escudero, J., Ramazani, V. Fallah, Fariña, L., Fattorini, A., Ferrara, G., Ferrarotto, F., Fiasson, A., Foffano, L., Font, L., Coromina, L. Freixas, Fröse, S., Fukami, S., Fukazawa, Y., López, R. J. Garcia, Garcia, E., Garczarczyk, M., López, R. J. García, Gasbarra, C., Gasparrini, D., Gasparyan, S., Gaug, M., Geyer, D., Paiva, J. G. Giesbrecht, Giglietto, N., Giordano, F., Gliwny, P., Godinović, N., Grau, R., Green, D., Green, J. G., Gunji, S., Günther, P., Hackfeld, J., Hadasch, D., Hahn, A., Hashiyama, K., Hassan, T., Hayashi, K., Heckmann, L., Heller, M., Llorente, J. Herrera, Hirotani, K., Hoffmann, D., Horns, D., Houles, J., Hrabovsky, M., Hrupec, D., Hui, D., Hütten, M., Iarlori, M., Imazawa, R., Inada, T., Inome, Y., Ioka, K., Iori, M., Iotov, R., Ishio, K., Jacquemont, M., Martínez, I. Jiménez, Jobst, E., Jormanainen, J., Jurysek, J., Kagaya, M., Karas, V., Katagiri, H., Kataoka, J., Kerszberg, D., Kluge, G. W., Kobayashi, Y., Kohri, K., Kong, A., Kouch, P. M., Kubo, H., Kushida, J., Lainez, M., Lamanna, G., Lamastra, A., Flour, T. Le, Leone, F., Lindfors, E., Linhoff, L., Linhoff, M., Lombardi, S., Longo, F., Loporchio, S., Lorini, A., Bahilo, J. Lozano, Luque-Escamilla, P. L., Lyard, E., Lezáun, M. Láinez, López-Coto, R., López-Moya, M., López-Oramas, A., Fraga, B. Machado de Oliveira, Majumdar, P., Makariev, M., Mandat, D., Maneva, G., Manganaro, M., Mangano, S., Mang, N., Manicò, G., Mannheim, K., Mariotti, M., Marquez, P., Marsella, G., Martinez, O., Martínez, G., Martínez, M., Martí, J., Mas-Aguilar, A., Maurin, G., Mazin, D., Menchiari, S., Mender, S., Guillen, E. Mestre, Micanovic, S., Miceli, D., Miener, T., Miranda, J. M., Mirzoyan, R., Mizuno, T., Mićanović, S., González, M. Molero, Molina, E., Mondal, H. A., Montaruli, T., Monteiro, I., Moralejo, A., Morcuende, D., Morselli, A., Moya, V., Muraishi, H., Murase, K., Nagataki, S., Nakamori, T., Nanci, C., Neronov, A., Neustroev, V., Nickel, L., Rosillo, M. Nievas, Nigro, C., Nikolić, L., Nilsson, K., Nishijima, K., Ekoume, T. Njoh, Noda, K., Nosek, D., Nozaki, S., Ohishi, M., Ohtani, Y., Oka, T., Okumura, A., Orito, R., Otero-Santos, J., Paiano, S., Palatiello, M., Paneque, D., Pantaleo, F. R., Paoletti, R., Paredes, J. M., Pavletić, L., Pech, M., Pecimotika, M., Peresano, M., Persic, M., Pfeiffle, F., Pietropaolo, E., Pihet, M., Pirola, G., Plard, C., Podobnik, F., Poireau, V., Polo, M., Pons, E., Moroni, P. G. Prada, Prandini, E., Prast, J., Principe, G., Priyadarshi, C., Prouza, M., Rando, R., Rhode, W., Ribó, M., Rico, J., Righi, C., Rizi, V., Fernandez, G. Rodriguez, Frías, M. D. Rodríguez, Sahakyan, N., Saito, T., Sakurai, S., Sanchez, D. A., Satalecka, K., Sato, M., Sato, Y., Saturni, F. G., Savchenko, V., Schleicher, B., Schmidt, K., Schmuckermaier, F., Schubert, J. L., Schussler, F., Schweizer, T., Sciaccaluga, A., Siegert, T., Silvia, R., Sitarek, J., Sliusar, V., Sobczynska, D., Spolon, A., Stamerra, A., Strišković, J., Strom, D., Strzys, M., Suda, Y., Suutarinen, S., Šarić, T., Tajima, H., Takahashi, H., Takahashi, M., Takata, J., Takeishi, R., Tam, P. H. T., Tanaka, S. J., Tateishi, D., Tavecchio, F., Temnikov, P., Terada, Y., Terauchi, K., Terzić, T., Teshima, M., Tluczykont, M., Tokanai, F., Torres, D. F., Tosti, L., Travnicek, P., Truzzi, S., Tutone, A., Ubach, S., Vacula, M., Vallania, P., van Scherpenberg, J., Acosta, M. Vazquez, Ventura, S., Verguilov, V., Viale, I., Vigliano, A., Vigorito, C. F., Visentin, E., Vitale, V., Voutsinas, G., Vovk, I., Vuillaume, T., Acosta, M. Vázquez, Walter, R., Wei, Z., Will, M., Yamamoto, T., Yamazaki, R., Yoshida, T., Yoshikoshi, T., and Zywucka, N.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
Aims. LST-1, the prototype of the Large-Sized Telescope for the upcoming Cherenkov Telescope Array Observatory, is concluding its commissioning in Observatorio del Roque de los Muchachos on the island of La Palma. The proximity of LST-1 (Large-Sized Telescope 1) to the two MAGIC (Major Atmospheric Gamma Imaging Cherenkov) telescopes permits observations of the same gamma-ray events with both systems. Methods. We describe the joint LST-1+MAGIC analysis pipeline and use simultaneous Crab Nebula observations and Monte Carlo simulations to assess the performance of the three-telescope system. The addition of the LST-1 telescope allows the recovery of events in which one of the MAGIC images is too dim to survive analysis quality cuts. Results. Thanks to the resulting increase in the collection area and stronger background rejection, we find a significant improvement in sensitivity, allowing the detection of 30% weaker fluxes in the energy range between 200 GeV and 3 TeV. The spectrum of the Crab Nebula, reconstructed in the energy range ~60 GeV to ~10 TeV, is in agreement with previous measurements., Comment: Accepted for publication in Astronomy & Astrophysics
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- 2023
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16. Entanglement entropy from non-equilibrium lattice simulations
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Bulgarelli, Andrea and Panero, Marco
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High Energy Physics - Lattice - Abstract
Entanglement entropy encodes important features of strongly interacting quantum many-body systems and gauge theories, but its analytical study is still limited to systems with high level of symmetry. This motivates the search for efficient techniques to investigate this quantity numerically, through Monte Carlo calculations on the lattice. In this contribution, we discuss the computation of the entropic c-function by means of an algorithm based on Jarzynski's equality, which is an exact theorem from non equilibrium statistical mechanics. After presenting benchmark results for the Ising model in two dimensions, where our algorithm successfully reproduces the analytical predictions from conformal field theory, we discuss its generalization to the three-dimensional Ising model, for which we were able to extract universal terms beyond the area law. Finally we point out some future generalizations of this calculation., Comment: 7 pages, contribution for the 40th International Symposium on Lattice Field Theory (Lattice 2023), July 31st - August 4th, 2023, Fermi National Accelerator Laboratory
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- 2023
17. AGILE gamma-ray detection of the exceptional GRB 221009A
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Tavani, M., Piano, G., Bulgarelli, A., Foffano, L., Ursi, A., Verrecchia, F., Pittori, C., Casentini, C., Giuliani, A., Longo, F., Panebianco, G., Di Piano, A., Baroncelli, L., Fioretti, V., Parmiggiani, N., Argan, A., Trois, A., Vercellone, S., Cardillo, M., Antonelli, L. A., Barbiellini, G., Caraveo, P., Cattaneo, P. W., Chen, A. W., Costa, E., Del Monte, E., Di Cocco, G., Donnarumma, I., Evangelista, Y., Feroci, M., Gianotti, F., Labanti, C., Lazzarotto, F., Lipari, P., Lucarelli, F., Marisaldi, M., Mereghetti, S., Morselli, A., Pacciani, L., Pellizzoni, A., Perotti, F., Picozza, P., Pilia, M., Rapisarda, M., Rappoldi, A., Rubini, A., Soffitta, P., Trifoglio, M., Vittorini, V., and D'Amico, F.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Gamma-ray emission in the MeV-GeV range from explosive cosmic events is of invaluable relevance to understanding physical processes related to the formation of neutron stars and black holes. Here we report on the detection by the AGILE satellite in the MeV-GeV energy range of the remarkable long-duration gamma-ray burst GRB 221009A. The AGILE onboard detectors have good exposure to GRB 221009A during its initial crucial phases. Hard X-ray/MeV emission in the prompt phase lasted hundreds of seconds, with the brightest radiation being emitted between 200 and 300 seconds after the initial trigger. Very intense GeV gamma-ray emission is detected by AGILE in the prompt and early afterglow phase up to 10,000 seconds. Time-resolved spectral analysis shows time-variable MeV-peaked emission simultaneous with intense power-law GeV radiation that persists in the afterglow phase. The coexistence during the prompt phase of very intense MeV emission together with highly nonthermal and hardening GeV radiation is a remarkable feature of GRB 221009A. During the prompt phase, the event shows spectrally different MeV and GeV emissions that are most likely generated by physical mechanisms occurring in different locations. AGILE observations provide crucial flux and spectral gamma-ray information regarding the early phases of GRB 221009A during which emission in the TeV range was reported., Comment: Accepted for publication in ApJL on September 19, 2023. Published online on October 17, 2023. Revised Figure 5 (June 13, 2024)
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- 2023
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18. Prospects for $\gamma$-ray observations of the Perseus galaxy cluster with the Cherenkov Telescope Array
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Consortium, The Cherenkov Telescope Array, Abe, K., Abe, S., Acero, F., Acharyya, A., Adam, R., Aguasca-Cabot, A., Agudo, I., Aguirre-Santaella, A., Alfaro, J., Alfaro, R., Alvarez-Crespo, N., Batista, R. Alves, Amans, J. -P., Amato, E., Angüner, E. O., Antonelli, L. A., Aramo, C., Araya, M., Arcaro, C., Arrabito, L., Asano, K., Ascasíbar, Y., Aschersleben, J., Ashkar, H., Stuani, L. Augusto, Baack, D., Backes, M., Baktash, A., Balazs, C., Balbo, M., Ballester, O., Larriva, A. Baquero, Martins, V. Barbosa, de Almeida, U. Barres, Barrio, J. A., Batista, P. I., Batkovic, I., Batzofin, R., Baxter, J., González, J. Becerra, Beck, G., Tjus, J. Becker, Benbow, W., Medrano, J. Bernete, Bernlöhr, K., Berti, A., Bertucci, B., Beshley, V., Bhattacharjee, P., Bhattacharyya, S., Bi, B., Biederbeck, N., Biland, A., Bissaldi, E., Biteau, J., Blanch, O., Blazek, J., Boisson, C., Bolmont, J., Bordas, P., Bosnjak, Z., Bottacini, E., Bradascio, F., Braiding, C., Bronzini, E., Brose, R., Brown, A. M., Brun, F., Brunetti, G., Bucciantini, N., Bulgarelli, A., Burelli, I., Burmistrov, L., Burton, M., Bylund, T., Calisse, P. G., Campoy-Ordaz, A., Cantlay, B. K., Capalbi, M., Caproni, A., Capuzzo-Dolcetta, R., Caraveo, P., Caroff, S., Carosi, R., Carquin, E., Carrasco, M. -S., Cascone, E., Cassol, F., Castro-Tirado, A. J., Cerasole, D., Cerruti, M., Chadwick, P., Chaty, S., Chen, A. W., Chernyakova, M., Chiavassa, A., Chudoba, J., Chytka, L., Cifuentes, A., Araujo, C. H. Coimbra, Conforti, V., Conte, F., Contreras, J. L., Cortina, J., Costa, A., Costantini, H., Cotter, G., Cristofari, P., Cuevas, O., Curtis-Ginsberg, Z., D'Amico, G., D'Ammando, F., Dalchenko, M., Dazzi, F., de Lavergne, M. de Bony, De Caprio, V., Laadim, F. De Frondat, Pino, E. M. de Gouveia Dal, De Lotto, B., De Lucia, M., De Martino, D., de Menezes, R., de Naurois, M., De Simone, N., de Souza, V., del Valle, M. V., Delagnes, E., Giler, A. G. Delgado, Delgado, C., Dell'aiera, M., della Volpe, D., Depaoli, D., Di Girolamo, T., Di Piano, A., Di Pierro, F., Di Tria, R., Di Venere, L., Diebold, S., Djannati-Ataï, A., Djuvsland, J., Dominik, R. M., Donini, A., Dorner, D., Dörner, J., Doro, M., Anjos, R. D. C. dos, Dournaux, J. -L., Duangchan, C., Dubos, C., Dumora, D., Dwarkadas, V. V., Ebr, J., Eckner, C., Egberts, K., Einecke, S., Elsässer, D., Emery, G., Godoy, M. Escobar, Escudero, J., Esposito, P., Ettori, S., Evoli, C., Falceta-Goncalves, D., Ramazani, V. Fallah, Fattorini, A., Faure, A., Fedorova, E., Fegan, S., Feijen, K., Feng, Q., Ferrand, G., Ferrarotto, F., Fiandrini, E., Fiasson, A., Filipovic, M., Fioretti, V., Foffano, L., Guiteras, L. Font, Fontaine, G., Fröse, S., Fukazawa, Y., Fukui, Y., Gaggero, D., Galanti, G., Gallozzi, S., Gammaldi, V., Garczarczyk, M., Gasbarra, C., Gasparrini, D., Gaug, M., Ghalumyan, A., Gianotti, F., Giarrusso, M., Giesbrecht, J., Giglietto, N., Giordano, F., Glicenstein, J. -F., Göksu, H., Goldoni, P., González, J. M., González, M. M., Coelho, J. Goulart, Granot, J., Grau, R., Gréaux, L., Green, D., Green, J. G., Grenier, I., Grolleron, G., Grube, J., Gueta, O., Hackfeld, J., Hadasch, D., Hamal, P., Hanlon, W., Hara, S., Harvey, V. M., Hassan, T., Heckmann, L., Heller, M., Cadena, S. Hernández, Hervet, O., Hie, J., Hiroshima, N., Hnatyk, B., Hnatyk, R., Hoang, J., Hoffmann, D., Hofmann, W., Holder, J., Horan, D., Horvath, P., Hrupec122, D., Hütten, M., Iarlori, M., Inada, T., Incardona, F., Inoue, S., Iocco, F., Iori, M., Jamrozy, M., Janecek, P., Jankowsky, F., Jarnot, C., Jean, P., Martínez, I. Jiménez, Jin, W., Juramy-Gilles, C., Jurysek, J., Kagaya, M., Kantzas, D., Karas, V., Katagiri, H., Kataoka, J., Kaufmann, S., Kerszberg, D., Khélifi, B., Kissmann, R., Kleiner, T., Kluge, G., Kluźniak, W., Knödlseder, J., Kobayashi, Y., Kohri, K., Komin, N., Kornecki, P., Kosack, K., Kowal, G., Kubo, H., Kushida, J., La Barbera, A., La Palombara, N., Láinez, M., Lamastra, A., Lapington, J., Laporte, P., Lazarević, S., Leitgeb, F., Lemoine-Goumard, M., Lenain, J. -P., Leone, F., Leto, G., Leuschner, F., Lindfors, E., Linhoff, M., Liodakis, I., Lombardi, S., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Luque-Escamilla, P. L., Macias, O., Mackey, J., Majumdar, P., Malyshev, D., Mandat, D., Manganaro, M., Manicò, G., Mariotti, M., Markoff, S., Márquez, I., Marquez, P., Marsella, G., Martínez, G. A., Martínez, M., Martinez, O., Marty, C., Mas-Aguilar, A., Mastropietro, M., Maurin, G., Mazin, D., Melkumyan, D., Mello, A. J. T. S., Meunier, J. -L., Meyer, D. M. -A., Meyer, M., Miceli, D., Michailidis, M., Michałowski, J., Miener, T., Miranda, J. M., Mitchell, A., Mizote, M., Mizuno, T., Moderski, R., Molero, M., Molfese, C., Molina, E., Montaruli, T., Morcuende, D., Morik, K., Morlino, G., Morselli, A., Moulin, E., Zamanillo, V. Moya, Munari, K., Murach, T., Muraczewski, A., Muraishi, H., Nagataki, S., Nakamori, T., Nemmen, R., Neyroud, N., Nickel, L., Niemiec, J., Nieto, D., Rosillo, M. Nievas, Nikołajuk, M., Nishijima, K., Noda, K., Nosek, D., Novotny, V., Nozaki, S., O'Brien, P., Ohishi, M., Ohtani, Y., Okumura, A., Olive, J. -F., Olmi, B., Ong, R. A., Orienti, M., Orito, R., Orlandini, M., Orlando, E., Ostrowski, M., Oya, I., Pagliaro, A., Palatiello, M., Panebianco, G., Paneque, D., Pantaleo, F. R., Paoletti, R., Paredes, J. M., Parmiggiani, N., Patel, S. R., Patricelli, B., Pavlović, D., Pech, M., Pecimotika, M., Pensec, U., Peresano, M., Pérez-Romero, J., Peron, G., Persic, M., Petrucci, P. -O., Petruk, O., Piano, G., Pierre, E., Pietropaolo, E., Pintore, F., Pirola, G., Pita, S., Plard, C., Podobnik, F., Pohl, M., Polo, M., Pons, E., Ponti, G., Prandini, E., Prast, J., Principe, G., Priyadarshi, C., Produit, N., Pueschel, E., Pühlhofer, G., Pumo, M. L., Punch, M., Queiroz, F., Quirrenbach, A., Rainò, S., Rando, R., Razzaque, S., Recchia, S., Regeard, M., Reichherzer, P., Reimer, A., Reimer, O., Reisenegger, A., Rhode, W., Ribeiro, D., Ribó, M., Richtler, T., Rico, J., Rieger, F., Righi, C., Riitano, L., Rizi, V., Roache, E., Fernandez, G. Rodriguez, Rodríguez-Vázquez, J. J., Romano, P., Romeo, G., Rosado, J., de Leon, A. Rosales, Rowell, G., Rudak, B., Rulten, C. B., Russo, F., Sadeh, I., Saha, L., Saito, T., Salzmann, H., Sanchez, D., Sánchez-Conde, M., Sangiorgi, P., Sano, H., Santander, M., Santangelo, A., Santos-Lima, R., Sanuy, A., Šarić, T., Sarkar, A., Sarkar, S., Satalecka, K., Saturni, F. G., Savchenko, V., Scherer, A., Schipani, P., Schleicher, B., Schubert, J. L., Schussler, F., Schwanke, U., Schwefer, G., Arroyo, M. Seglar, Seiji, S., Semikoz, D., Sergijenko, O., Servillat, M., Sguera, V., Shang, R. Y., Sharma, P., Siejkowski, H., Sinha, A., Siqueira, C., Sliusar, V., Slowikowska, A., Sol, H., Specovius, A., Spencer, S. T., Spiga, D., Stamerra, A., Stanič, S., Starecki, T., Starling, R., Stawarz, Ł., Steppa, C., Stolarczyk, T., Strišković, J., Suda, Y., Suomijärvi, T., Tajima, H., Tak, D., Takahashi, M., Takeishi, R., Tanaka, S. J., Tavernier, T., Tejedor, L. A., Terauchi, K., Terrier, R., Teshima, M., Tian, W. W., Tibaldo, L., Tibolla, O., Torradeflot, F., Torres, D. F., Torresi, E., Tosti, G., Tosti, L., Tothill, N., Toussenel, F., Touzard, V., Tramacere, A., Travnicek, P., Tripodo, G., Truzzi, S., Tsiahina, A., Tutone, A., Vacula, M., Vallage, B., Vallania, P., van Eldik, C., van Scherpenberg, J., Vandenbroucke, J., Vassiliev, V., Acosta, M. Vázquez, Vecchi, M., Ventura, S., Vercellone, S., Verna, G., Viana, A., Viaux, N., Vigliano, A., Vigorito, C. F., Vitale, V., Vodeb, V., Voisin, V., Vorobiov, S., Voutsinas, G., Vovk, I., Vuillaume, T., Wagner, S. J., Walter, R., Wechakama, M., White, R., Wierzcholska, A., Will, M., Williams, D. A., Wohlleben, F., Wolter, A., Yamamoto, T., Yamazaki, R., Yoshida, T., Yoshikoshi, T., Zacharias, M., Zaharijas, G., Zavrtanik, D., Zavrtanik, M., Zdziarski, A. A., Zech, A., Zhdanov, V. I., Živec, M., Zuriaga-Puig, J., and Luque, P. De la Torre
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Cosmology and Nongalactic Astrophysics ,High Energy Physics - Phenomenology - Abstract
Galaxy clusters are expected to be dark matter (DM) reservoirs and storage rooms for the cosmic-ray protons (CRp) that accumulate along the cluster's formation history. Accordingly, they are excellent targets to search for signals of DM annihilation and decay at gamma-ray energies and are predicted to be sources of large-scale gamma-ray emission due to hadronic interactions in the intracluster medium. We estimate the sensitivity of the Cherenkov Telescope Array (CTA) to detect diffuse gamma-ray emission from the Perseus galaxy cluster. We perform a detailed spatial and spectral modelling of the expected signal for the DM and the CRp components. For each, we compute the expected CTA sensitivity. The observing strategy of Perseus is also discussed. In the absence of a diffuse signal (non-detection), CTA should constrain the CRp to thermal energy ratio within the radius $R_{500}$ down to about $X_{500}<3\times 10^{-3}$, for a spatial CRp distribution that follows the thermal gas and a CRp spectral index $\alpha_{\rm CRp}=2.3$. Under the optimistic assumption of a pure hadronic origin of the Perseus radio mini-halo and depending on the assumed magnetic field profile, CTA should measure $\alpha_{\rm CRp}$ down to about $\Delta\alpha_{\rm CRp}\simeq 0.1$ and the CRp spatial distribution with 10% precision. Regarding DM, CTA should improve the current ground-based gamma-ray DM limits from clusters observations on the velocity-averaged annihilation cross-section by a factor of up to $\sim 5$, depending on the modelling of DM halo substructure. In the case of decay of DM particles, CTA will explore a new region of the parameter space, reaching models with $\tau_{\chi}>10^{27}$s for DM masses above 1 TeV. These constraints will provide unprecedented sensitivity to the physics of both CRp acceleration and transport at cluster scale and to TeV DM particle models, especially in the decay scenario., Comment: 93 pages (including author list, appendix and references), 143 figures. Submitted to JCAP
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- 2023
19. The Compton Spectrometer and Imager
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Tomsick, John A., Boggs, Steven E., Zoglauer, Andreas, Hartmann, Dieter, Ajello, Marco, Burns, Eric, Fryer, Chris, Karwin, Chris, Kierans, Carolyn, Lowell, Alexander, Malzac, Julien, Roberts, Jarred, Saint-Hilaire, Pascal, Shih, Albert, Siegert, Thomas, Sleator, Clio, Takahashi, Tadayuki, Tavecchio, Fabrizio, Wulf, Eric, Beechert, Jacqueline, Gulick, Hannah, Joens, Alyson, Lazar, Hadar, Neights, Eliza, Oliveros, Juan Carlos Martinez, Matsumoto, Shigeki, Melia, Tom, Yoneda, Hiroki, Amman, Mark, Bal, Dhruv, von Ballmoos, Peter, Bates, Hugh, Böttcher, Markus, Bulgarelli, Andrea, Cavazzuti, Elisabetta, Chang, Hsiang-Kuang, Chen, Claire, Chu, Che-Yen, Ciabattoni, Alex, Costamante, Luigi, Dreyer, Lente, Fioretti, Valentina, Fenu, Francesco, Gallego, Savitri, Ghirlanda, Giancarlo, Grove, Eric, Huang, Chien-You, Jean, Pierre, Khatiya, Nikita, Knödlseder, Jürgen, Krause, Martin, Leising, Mark, Lewis, Tiffany R., Lommler, Jan Peter, Marcotulli, Lea, Martinez-Castellanos, Israel, Mittal, Saurabh, Negro, Michela, Nussirat, Samer Al, Nakazawa, Kazuhiro, Oberlack, Uwe, Palmore, David, Panebianco, Gabriele, Parmiggiani, Nicolo, Parsotan, Tyler, Pike, Sean N., Rogers, Field, Schutte, Hester, Sheng, Yong, Smale, Alan P., Smith, Jacob, Trigg, Aaron, Venters, Tonia, Watanabe, Yu, and Zhang, Haocheng
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The Compton Spectrometer and Imager (COSI) is a NASA Small Explorer (SMEX) satellite mission in development with a planned launch in 2027. COSI is a wide-field gamma-ray telescope designed to survey the entire sky at 0.2-5 MeV. It provides imaging, spectroscopy, and polarimetry of astrophysical sources, and its germanium detectors provide excellent energy resolution for emission line measurements. Science goals for COSI include studies of 0.511 MeV emission from antimatter annihilation in the Galaxy, mapping radioactive elements from nucleosynthesis, determining emission mechanisms and source geometries with polarization measurements, and detecting and localizing multimessenger sources. The instantaneous field of view for the germanium detectors is >25% of the sky, and they are surrounded on the sides and bottom by active shields, providing background rejection as well as allowing for detection of gamma-ray bursts and other gamma-ray flares over most of the sky. In the following, we provide an overview of the COSI mission, including the science, the technical design, and the project status., Comment: 8 pages
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- 2023
20. The cosipy library: COSI's high-level analysis software
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Martinez-Castellanos, Israel, Gallego, Savitri, Huang, Chien-You, Karwin, Chris, Kierans, Carolyn, Lommler, Jan Peter, Mittal, Saurabh, Negro, Michela, Neights, Eliza, Pike, Sean N., Sheng, Yong, Siegert, Thomas, Yoneda, Hiroki, Zoglauer, Andreas, Tomsick, John A., Boggs, Steven E., Hartmann, Dieter, Ajello, Marco, Burns, Eric, Fryer, Chris, Lowell, Alexander, Malzac, Julien, Roberts, Jarred, Saint-Hilaire, Pascal, Shih, Albert, Sleator, Clio, Takahashi, Tadayuki, Tavecchio, Fabrizio, Wulf, Eric, Beechert, Jacqueline, Gulick, Hannah, Joens, Alyson, Lazar, Hadar, Oliveros, Juan Carlos Martinez, Matsumoto, Shigeki, Melia, Tom, Amman, Mark, Bal, Dhruv, von Ballmoos, Peter, Bates, Hugh, Böttcher, Markus, Bulgarelli, Andrea, Cavazzuti, Elisabetta, Chang, Hsiang-Kuang, Chen, Claire, Chu, Che-Yen, Ciabattoni, Alex, Costamante, Luigi, Dreyer, Lente, Fioretti, Valentina, Fenu, Francesco, Ghirlanda, Giancarlo, Grove, Eric, Jean, Pierre, Khatiya, Nikita, Knödlseder, Jürgen, Krause, Martin, Leising, Mark, Lewis, Tiffany R., Marcotulli, Lea, Nussirat, Samer Al, Nakazawa, Kazuhiro, Oberlack, Uwe, Palmore, David, Panebianco, Gabriele, Parmiggiani, Nicolo, Parsotan, Tyler, Rogers, Field, Schutte, Hester, Smale, Alan P., Smith, Jacob, Trigg, Aaron, Venters, Tonia, Watanabe, Yu, and Zhang, Haocheng
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The Compton Spectrometer and Imager (COSI) is a selected Small Explorer (SMEX) mission launching in 2027. It consists of a large field-of-view Compton telescope that will probe with increased sensitivity the under-explored MeV gamma-ray sky (0.2-5 MeV). We will present the current status of cosipy, a Python library that will perform spectral and polarization fits, image deconvolution, and all high-level analysis tasks required by COSI's broad science goals: uncovering the origin of the Galactic positrons, mapping the sites of Galactic nucleosynthesis, improving our models of the jet and emission mechanism of gamma-ray bursts (GRBs) and active galactic nuclei (AGNs), and detecting and localizing gravitational wave and neutrino sources. The cosipy library builds on the experience gained during the COSI balloon campaigns and will bring the analysis of data in the Compton regime to a modern open-source likelihood-based code, capable of performing coherent joint fits with other instruments using the Multi-Mission Maximum Likelihood framework (3ML). In this contribution, we will also discuss our plans to receive feedback from the community by having yearly software releases accompanied by publicly-available data challenges.
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- 2023
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21. Is lipoprotein(a) measurement important for cardiovascular risk stratification in children and adolescents?
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Marco Giussani, Antonina Orlando, Elena Tassistro, Erminio Torresani, Giulia Lieti, Ilenia Patti, Claudia Colombrita, Ilaria Bulgarelli, Laura Antolini, Gianfranco Parati, and Simonetta Genovesi
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Lipoprotein (a) ,LDL cholesterol ,Children ,Cardiovascular risk ,Pediatrics ,RJ1-570 - Abstract
Abstract Background Elevated lipoprotein (Lp(a)) levels are associated with increased risk of atherosclerotic processes and cardiovascular events in adults. The amount of Lp(a) is mainly genetically determined. Therefore, it is important to identify individuals with elevated Lp(a) as early as possible, particularly if other cardiovascular risk factors are present. The purpose of the study was to investigate whether, in a population of children and adolescents already followed for the presence of one or more cardiovascular risk factors (elevated blood pressure (BP), and/or excess body weight, and/or dyslipidemia), the measurement of Lp(a) can be useful for better stratifying their risk profile. Methods In a sample of 195 children and adolescents, height, body weight, waist circumference and systolic (SBP) and diastolic (DBP) BP were measured. Body Mass Index (BMI) and SBP and DBP z-scores were calculated. Plasma Lp(a), total cholesterol, high-density lipoprotein (HDL), triglycerides, glucose, insulin, uric acid and creatinine were assessed. Low-density lipoprotein (LDL) cholesterol was calculated with the Friedewald formula. High Lp(a) was defined as ≥ 75 nmol/L and high LDL cholesterol as ≥ 3.37 mmol/L. Results Our sample of children and adolescents (54.4% males, mean age 11.5 years) had median LDL cholesterol and Lp(a) values equal to 2.54 (interquartile range, IQR: 2.07–3.06) mmol/L and 22 (IQR: 7.8–68.6) nmol/L respectively. 13.8% of children had LDL cholesterol ≥ 3.37 mmol/L and 22.6 Lp(a) values ≥ 75 nmol/L. Lp(a) values were higher in children of normal weight than in those with excess weight (p = 0.007), but the difference disappeared if normal weight children referred for dyslipidemia only were excluded from the analysis (p = 0.210). 69.4% of children had normal Lp(a) and LDL cholesterol values and only 6.2% showed both elevated Lp(a) and LDL cholesterol levels. However, 16.6% of the sample, despite having normal LDL cholesterol, had elevated Lp(a) values. Multivariable analyses showed a significant association of LDL cholesterol both with Lp(a) values, and with the presence of elevated Lp(a) levels. For each mmol/L increase in LDL cholesterol the risk of having an elevated Lp(a) value increased by 73%. There was an inverse correlation between BMI z-score and Lp(a). Neither BP z-scores, nor other biochemical parameters were associated with Lp(a). Conclusions In our population more than one out of five children had elevated Lp(a) values, and in about 17% of children elevated Lp(a) values were present in the absence of increased LDL cholesterol. Our results suggest that Lp(a) measurement can be useful to better define the cardiovascular risk profile in children and adolescents already followed for the presence of other cardiovascular risk factors such as elevated BP, excess body weight and high LDL cholesterol.
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- 2024
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22. Stability and Change in Young Children's Linguistic Experience during the COVID-19 Pandemic: Insight from a Citizen-Science Sample in the United States
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Federica Bulgarelli and Christine E. Potter
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Early in the COVID-19 pandemic, extensive lockdowns interrupted daily routines, including childcare. We asked whether these interruptions, and the inevitable changes in the people with whom children spent their waking hours, caused changes in the languages that children heard. We retrospectively queried parents of young children (0-4 years) in the US about childcare arrangements and exposure to English and non-English languages at four timepoints from February 2020 to September 2021. Despite discontinuity in childcare arrangements, we found that children's exposure to English versus other languages remained relatively stable. We also identified demographic variables (child age at pandemic onset, parental proficiency in a non-English language) that consistently predicted exposure to non-English languages. Thus, multilingually-exposed children in this population did not appear to significantly gain or lose the opportunity to hear non-English languages overall. These results provide insight into the experiences of this unique cohort and inform our understanding of how language development can be shaped by complex environmental systems.
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- 2024
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23. Observations of the Crab Nebula and Pulsar with the Large-Sized Telescope Prototype of the Cherenkov Telescope Array
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Project, CTA-LST, Abe, H., Abe, K., Abe, S., Aguasca-Cabot, A., Agudo, I., Crespo, N. Alvarez, Antonelli, L. A., Aramo, C., Arbet-Engels, A., Arcaro, C., Artero, M., Asano, K., Aubert, P., Baktash, A., Bamba, A., Larriva, A. Baquero, Baroncelli, L., de Almeida, U. Barres, Barrio, J. A., Batkovic, I., Baxter, J., González, J. Becerra, Bernardini, E., Bernardos, M. I., Medrano, J. Bernete, Berti, A., Bhattacharjee, P., Biederbeck, N., Bigongiari, C., Bissaldi, E., Blanch, O., Bonnoli, G., Bordas, P., Borghese, A., Bulgarelli, A., Burelli, I., Buscemi, M., Cardillo, M., Caroff, S., Carosi, A., Cassol, F., Cauz, D., Ceribella, G., Chai, Y., Cheng, K., Chiavassa, A., Chikawa, M., Chytka, L., Cifuentes, A., Contreras, J. L., Cortina, J., Costantini, H., D'Amico, G., Dalchenko, M., De Angelis, A., de Lavergne, M. de Bony, De Lotto, B., de Menezes, R., Deleglise, G., Delgado, C., Mengual, J. Delgado, della Volpe, D., Dellaiera, M., Depaoli, D., Di Piano, A., Di Pierro, F., Di Tria, R., Di Venere, L., Díaz, C., Dominik, R. M., Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Elsässer, D., Emery, G., Escudero, J., Ramazani, V. Fallah, Ferrara, G., Ferrarotto, F., Fiasson, A., Coromina, L. Freixas, Fröse, S., Fukami, S., Fukazawa, Y., Garcia, E., López, R. Garcia, Gasbarra, C., Gasparrini, D., Geyer, F., Paiva, J. Giesbrecht, Giglietto, N., Giordano, F., Giro, E., Gliwny, P., Godinovic, N., Grau, R., Green, D., Green, J., Gunji, S., Hackfeld, J., Hadasch, D., Hahn, A., Hashiyama, K., Hassan, T., Hayashi, K., Heckmann, L., Heller, M., Llorente, J. Herrera, Hirotani, K., Hoffmann, D., Horns, D., Houles, J., Hrabovsky, M., Hrupec, D., Hui, D., Hütten, M., Iarlori, M., Imazawa, R., Inada, T., Inome, Y., Ioka, K., Iori, M., Ishio, K., Iwamura, Y., Jacquemont, M., Martinez, I. Jimenez, Jurysek, J., Kagaya, M., Karas, V., Katagiri, H., Kataoka, J., Kerszberg, D., Kobayashi, Y., Kong, A., Kubo, H., Kushida, J., Lainez, M., Lamanna, G., Lamastra, A., Flour, T. Le, Linhoff, M., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Lorini, A., Luque-Escamilla, P. L., Majumdar, P., Makariev, M., Mandat, D., Manganaro, M., Manicò, G., Mannheim, K., Mariotti, M., Marquez, P., Marsella, G., Martí, J., Martinez, O., Martínez, G., Martínez, M., Marusevec, P., Mas-Aguilar, A., Maurin, G., Mazin, D., Guillen, E. Mestre, Micanovic, S., Miceli, D., Miener, T., Miranda, J. M., Mirzoyan, R., Mizuno, T., Gonzalez, M. Molero, Molina, E., Montaruli, T., Monteiro, I., Moralejo, A., Morcuende, D., Morselli, A., Mrakovcic, K., Murase, K., Nagai, A., Nagataki, S., Nakamori, T., Nickel, L., Nievas, M., Nishijima, K., Noda, K., Nosek, D., Nozaki, S., Ohishi, M., Ohtani, Y., Oka, T., Okazaki, N., Okumura, A., Orito, R., Otero-Santos, J., Palatiello, M., Paneque, D., Pantaleo, F. R., Paoletti, R., Paredes, J. M., Pech, M., Pecimotika, M., Peresano, M., Pérez, A., Pietropaolo, E., Pirola, G., Plard, C., Podobnik, F., Poireau, V., Polo, M., Pons, E., Prandini, E., Prast, J., Principe, G., Priyadarshi, C., Prouza, M., Rando, R., Rhode, W., Ribó, M., Rizi, V., Fernandez, G. Rodriguez, Ruiz, J. E., Saito, T., Sakurai, S., Sanchez, D. A., Šarić, T., Sato, Y., Saturni, F. G., Schleicher, B., Schmuckermaier, F., Schubert, J. L., Schussler, F., Schweizer, T., Arroyo, M. Seglar, Silvia, R., Sitarek, J., Sliusar, V., Spolon, A., Strišković, J., Strzys, M., Suda, Y., Sunada, Y., Tajima, H., Takahashi, H., Takahashi, M., Takata, J., Takeishi, R., Tam, P. H. T., Tanaka, S. J., Tateishi, D., Tejedor, L. A., Temnikov, P., Terada, Y., Terauchi, K., Terzic, T., Teshima, M., Tluczykont, M., Tokanai, F., Torres, D. F., Travnicek, P., Truzzi, S., Tutone, A., Uhlrich, G., Vacula, M., Vallania, P., van Scherpenberg, J., Acosta, M. Vázquez, Verguilov, V., Viale, I., Vigliano, A., Vigorito, C. F., Vitale, V., Voutsinas, G., Vovk, I., Vuillaume, T., Walter, R., Will, M., Yamamoto, T., Yamazaki, R., Yoshida, T., Yoshikoshi, T., Zywucka, N., Bernloehr, K., Gueta, O., Kosack, K., Maier, G., Watson, J., Rijeka, University of, Physics, Department of, Rijeka, Croatia, Physics, Institute for Theoretical, Astrophysics, Würzburg, Universität, Nord, Campus Hubland, Würzburg, Germany, Physik, Institut für Theoretische, IV, Lehrstuhl, Plasma-Astroteilchenphysik, Bochum, Ruhr-Universität, Bochum, La Sapienza, INFN Sezione di Roma, Rome, Italy, ILANCE, Laboratory, CNRS - University of Tokyo International Research, Kashiwa, Chiba, Japan, Program, Physics, Science, Graduate School of Advanced, Engineering, University, Hiroshima, Hiroshima, Vergata, INFN Sezione di Roma Tor, Physics, Faculty of, Informatics, Applied, Lodz, University of, Lodz, Poland, Split, University of, FESB, Split, University, Yamagata, Yamagata, University, Tohoku, Institute, Astronomical, Aobaku, Sendai, Osijek, Josip Juraj Strossmayer University of, Osijek, dell'Aquila, INFN Dipartimento di Scienze Fisiche e Chimiche - Università degli Studi, Institute, Gran Sasso Science, L'Aquila, Oiwakecho, Kitashirakawa, Kyoto, Astronomy, Department of, Geneva, University of, Versoix, Switzerland, Sciences, Astronomical Institute of the Czech Academy of, Prague, Republic, Czech, Science, Faculty of, University, Ibaraki, Mito, Ibaraki, University, Waseda, Shinjuku, Tokyo, di Trieste, INFN Sezione, di Trieste, Università degli Studi, Trieste, INFN, di Siena, Università degli Studi, Fisiche, Dipartimento di Scienze, dell'Ambiente, della Terra e, di Fisica, Sezione, Siena, de Jaén, Escuela Politécnica Superior, de Jaén, Universidad, Lagunillas, Campus Las, Jaén, Spain, Physics, Saha Institute of Nuclear, Bidhannagar, Kolkata, India, Research, Institute for Nuclear, Energy, Nuclear, Sciences, Bulgarian Academy of, Sofia, Bulgaria, Sciences, FZU - Institute of Physics of the Czech Academy of, Praha, di Palermo, Dipartimento di Fisica e Chimica 'E. Segrè' Università degli Studi, Scienze, via delle, Palermo, de Electronica, Grupo, de Madrid, Universidad Complutense, Complutense, Av., Madrid, Physics, Department of Applied, Zagreb, University of, Zagreb, Center, Hiroshima Astrophysical Science, Higashi-Hiroshima, RIKEN, Physical, Institute of, Research, Chemical, Wako, Saitama, University, Charles, Particle, Institute of, Physics, Nuclear, Physics, Division of, Astronomy, Science, Graduate School of, University, Kyoto, Sakyo-ku, Research, Institute for Space-Earth Environmental, University, Nagoya, Chikusa-ku, Nagoya, Institute, Kobayashi-Maskawa, Particles, for the Origin of, Universe, the, Technology, Graduate School of, Industrial, Sciences, Social, University, Tokushima, Tokushima, Sciences, Department of Physical, University, Aoyama Gakuin, Fuchinobe, Sagamihara, Kanagawa, IRFU, CEA, Paris-Saclay, Université, Gif-sur-Yvette, France, University, Saitama, Sakura-ku, city, Saitama, di Torino, Dipartimento di Fisica - Universitá degli Studi, Torino, University, Konan, Kobe, Hyogo, Japan), Heidelberg, Zeuthen, Saclay, CEA, Merisiers, Orme des, and France)
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
CTA (Cherenkov Telescope Array) is the next generation ground-based observatory for gamma-ray astronomy at very-high energies. The Large-Sized Telescope prototype (LST-1) is located at the Northern site of CTA, on the Canary Island of La Palma. LSTs are designed to provide optimal performance in the lowest part of the energy range covered by CTA, down to $\simeq 20$ GeV. LST-1 started performing astronomical observations in November 2019, during its commissioning phase, and it has been taking data since then. We present the first LST-1 observations of the Crab Nebula, the standard candle of very-high energy gamma-ray astronomy, and use them, together with simulations, to assess the basic performance parameters of the telescope. The data sample consists of around 36 hours of observations at low zenith angles collected between November 2020 and March 2022. LST-1 has reached the expected performance during its commissioning period - only a minor adjustment of the preexisting simulations was needed to match the telescope behavior. The energy threshold at trigger level is estimated to be around 20 GeV, rising to $\simeq 30$ GeV after data analysis. Performance parameters depend strongly on energy, and on the strength of the gamma-ray selection cuts in the analysis: angular resolution ranges from 0.12 to 0.40 degrees, and energy resolution from 15 to 50%. Flux sensitivity is around 1.1% of the Crab Nebula flux above 250 GeV for a 50-h observation (12% for 30 minutes). The spectral energy distribution (in the 0.03 - 30 TeV range) and the light curve obtained for the Crab Nebula agree with previous measurements, considering statistical and systematic uncertainties. A clear periodic signal is also detected from the pulsar at the center of the Nebula., Comment: Accepted in ApJ. v3: updated author list and acknowledgements, fixed typos and other minor issues
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- 2023
24. The First AGILE Solar Flare Catalog
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Ursi, Alessandro, Parmiggiani, Nicolò, Messerotti, Mauro, Pellizzoni, Alberto, Pittori, Carlotta, Longo, Francesco, Verrecchia, Francesco, Argan, Andrea, Bulgarelli, Andrea, Tavani, Marco, Tempesta, Patrizio, and D'Amico, Fabio
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Astrophysics - Solar and Stellar Astrophysics - Abstract
We report the Astrorivelatore Gamma ad Immagini LEggero (AGILE) observations of solar flares, detected by the on board anticoincidence system in the 80-200 keV energy range, from 2007 May 1st to 2022 August 31st. In more than 15 yr, AGILE detected 5003 X-ray, minute-lasting transients, compatible with a solar origin. A cross-correlation of these transients with the Geostationary Operational Environmental Satellites (GOES) official solar flare database allowed to associate an intensity class (i.e., B, C, M, or X) to 3572 of them, for which we investigated the main temporal and intensity parameters. The AGILE data clearly revealed the solar activity covering the last stages of the 23rd cycle, the whole 24th cycle, and the beginning of the current 25th cycle. In order to compare our results with other space missions operating in the high-energy range, we also analyzed the public lists of solar flares reported by RHESSI and Fermi Gamma-ray Burst Monitor. This catalog reports 1424 events not contained in the GOES official dataset, which, after statistical comparisons, are compatible with low-intensity, short-duration solar flares. Besides providing a further dataset of solar flares detected in the hard X-ray range, this study allowed to point out two main features: a longer persistence of the decay phase in the high-energy regime, with respect to the soft X-rays, and a tendency of the flare maximum to be reached earlier in the soft X-rays with respect to the hard X-rays. Both these aspects support a two-phase acceleration mechanism of electrons in the solar atmosphere., Comment: 22 pages, 10 figures
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- 2023
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25. Is lipoprotein(a) measurement important for cardiovascular risk stratification in children and adolescents?
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Giussani, Marco, Orlando, Antonina, Tassistro, Elena, Torresani, Erminio, Lieti, Giulia, Patti, Ilenia, Colombrita, Claudia, Bulgarelli, Ilaria, Antolini, Laura, Parati, Gianfranco, and Genovesi, Simonetta
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- 2024
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26. Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres
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Pallocca, Matteo, Molineris, Ivan, Berrino, Enrico, Marcozzi, Benedetta, Betti, Martina, Levati, Lauretta, D’Atri, Stefania, Menin, Chiara, Madonna, Gabriele, Ghiorzo, Paola, Bulgarelli, Jenny, Ferraresi, Virgina, Venesio, Tiziana, Rodolfo, Monica, Rivoltini, Licia, Lanfrancone, Luisa, Ascierto, Paolo Antonio, Mazzarella, Luca, Pelicci, Pier Giuseppe, De Maria, Ruggero, Ciliberto, Gennaro, Medico, Enzo, and Russo, Giandomenico
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- 2024
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27. Sequential immunotherapy and targeted therapy for metastatic BRAF V600 mutated melanoma: 4-year survival and biomarkers evaluation from the phase II SECOMBIT trial
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Ascierto, Paolo A., Casula, Milena, Bulgarelli, Jenny, Pisano, Marina, Piccinini, Claudia, Piccin, Luisa, Cossu, Antonio, Mandalà, Mario, Ferrucci, Pier Francesco, Guidoboni, Massimo, Rutkowski, Piotr, Ferraresi, Virginia, Arance, Ana, Guida, Michele, Maiello, Evaristo, Gogas, Helen, Richtig, Erika, Fierro, Maria Teresa, Lebbe, Celeste, Helgadottir, Hildur, Queirolo, Paola, Spagnolo, Francesco, Tucci, Marco, Del Vecchio, Michele, Cao, Maria Gonzales, Minisini, Alessandro Marco, De Placido, Sabino, Sanmamed, Miguel F., Mallardo, Domenico, Paone, Miriam, Vitale, Maria Grazia, Melero, Ignacio, Grimaldi, Antonio M., Giannarelli, Diana, Dummer, Reinhard, Sileni, Vanna Chiarion, and Palmieri, Giuseppe
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- 2024
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28. The value of routine blood work-up in clinical stratification and prognosis of patients with amyotrophic lateral sclerosis
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Gentile, Francesco, Maranzano, Alessio, Verde, Federico, Bettoni, Veronica, Colombo, Eleonora, Doretti, Alberto, Olivero, Marco, Scheveger, Francesco, Colombrita, Claudia, Bulgarelli, Ilaria, Spinelli, Edoardo Gioele, Torresani, Erminio, Messina, Stefano, Maderna, Luca, Agosta, Federica, Morelli, Claudia, Filippi, Massimo, Silani, Vincenzo, and Ticozzi, Nicola
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- 2024
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29. Entanglement entropy from non-equilibrium Monte Carlo simulations
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Bulgarelli, Andrea and Panero, Marco
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Quantum Physics ,Condensed Matter - Strongly Correlated Electrons ,High Energy Physics - Lattice ,High Energy Physics - Theory - Abstract
We study the entanglement entropy in lattice field theory using a simulation algorithm based on Jarzynski's theorem. We focus on the entropic c-function for the Ising model in two and in three dimensions: after validating our algorithm against known analytical results from conformal field theory in two dimensions, we present novel results for the three-dimensional case. We show that our algorithm, which is highly parallelized on graphics processing units, allows one to precisely determine the subleading corrections to the area law, which have been investigated in many recent works. Possible generalizations of this study to other strongly coupled theories are discussed., Comment: 1+33 pages; v2: typos corrected, matches published version
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- 2023
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30. Sensitivity of the Cherenkov Telescope Array to spectral signatures of hadronic PeVatrons with application to Galactic Supernova Remnants
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Consortium, The Cherenkov Telescope Array, Acero, F., Acharyya, A., Adam, R., Aguasca-Cabot, A., Agudo, I., Aguirre-Santaella, A., Alfaro, J., Aloisio, R., Crespo, N. Álvarez, Batista, R. Alves, Amati, L., Amato, E., Ambrosi, G., Angüner, E. O., Aramo, C., Arcaro, C., Armstrong, T., Asano, K., Ascasibar, Y., Aschersleben, J., Backes, M., Baktash, A., Balazs, C., Balbo, M., Ballet, J., Larriva, A. Baquero, Martins, V. Barbosa, de Almeida, U. Barres, Barrio, J. A., Bastieri, D., Baxter, J. R., Tjus, J. Becker, Benbow, W., Bernardos-Martín, M. I., Bernete, J., Berti, A., Bertucci, B., Beshley, V., Bhattacharjee, P., Bhattacharyya, S., Biland, A., Bissaldi, E., Biteau, J., Blanch, O., Bordas, P., Bottacini, E., Bregeon, J., Brose, R., Bucciantini, N., Bulgarelli, A., Capasso, M., Dolcetta, R. A. Capuzzo, Caraveo, P., Cardillo, M., Carosi, R., Casanova, S., Cascone, E., Cassol, F., Catalani, F., Cerruti, M., Chadwick, P., Chaty, S., Chen, A., Chernyakova, M., Chiavassa, A., Chudoba, J., Coimbra-Araujo, C., Conforti, V., Contreras, J. L., Costa, A., Costantini, H., Cristofari, P., Crocker, R., D'Amico, G., D'Ammando, F., De Angelis, A., De Caprio, V., Pino, E. M. de Gouveia Dal, Wilhelmi, E. de Ona, de Souza, V., Delgado, C., della Volpe, D., Depaoli, D., Di Girolamo, T., Di Pierro, F., Di Tria, R., Di Venere, L., Diebold, S., Djuvsland, J. I., Donini, A., Doro, M., Anjos, R. d. C. Dos, Dwarkadas, V. V., Einecke, S., Elsässer, D., Emery, G., Evoli, C., Falceta-Goncalves, D., Fedorova, E., Fegan, S., Ferrand, G., Fiandrini, E., Filipovic, M., Fioretti, V., Fiori, M., Foffano, L., Fontaine, G., Fukami, S., Galanti, G., Galaz, G., Gammaldi, V., Gasbarra, C., Ghalumyan, A., Ghirlanda, G., Giarrusso, M., Giavitto, G., Giglietto, N., Giordano, F., Giroletti, M., Giuliani, A., Giunti, L., Godinovic, N., Coelho, J. Goulart, Gréaux, L., Green, D., Grondin, M-H., Gueta, O., Gunji, S., Hassan, T., Heller, M., Hernández-Cadena, S., Hinton, J., Hnatyk, B., Hnatyk, R., Hoffmann, D., Hofmann, W., Holder, J., Horan, D., Horvath, P., Hrabovsky, M., Hrupec, D., Inada, T., Incardona, F., Inoue, S., Ishio, K., Jamrozy, M., Janecek, P., Martínez, I. Jiménez, Jin, W., Jung-Richardt, I., Jurysek, J., Kaaret, P., Karas, V., Katz, U., Kerszberg, D., Khélifi, B., Kieda, D. B., Kissmann, R., Kleiner, T., Kluge, G., Kluzniak, W., Knödlseder, J., Kobayashi, Y., Kohri, K., Komin, N., Kornecki, P., Kubo, H., La Palombara, N., Láinez, M., Lamastra, A., Lapington, J., Lemoine-Goumard, M., Lenain, J. -P., Leone, F., Leto, G., Leuschner, F., Lindfors, E., Liodakis, I., Lohse, T., Lombardi, S., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Luque-Escamilla, P. L., Macias, O., Mackey, J., Majumdar, P., Mandat, D., Manganaro, M., Manicò, G., Marconi, M., Martí, J., Martínez, G., Martinez, M., Martinez, O., Mello, A. J. T. S., Menchiari, S., Meyer, D. M. -A., Micanovic, S., Miceli, D., Miceli, M., Michalowski, J., Miener, T., Miranda, J. M., Mitchell, A., Mode, B., Moderski, R., Mohrmann, L., Molina, E., Montaruli, T., Morcuende, D., Morlino, G., Morselli, A., Mosè, M., Moulin, E., Mukherjee, R., Munari, K., Murach, T., Nagai, A., Nagataki, S., Nemmen, R., Niemiec, J., Nieto, D., Rosillo, M. Nievas, Nikolajuk, M., Nishijima, K., Noda, K., Novosyadlyj, B., Nozaki, S., Ohishi, M., Ohm, S., Ohtani, Y., Okumura, A., Olmi, B., Ong, R. A., Orienti, M., Orito, R., Orlandini, M., Orlando, E., Orlando, S., Ostrowski, M., Oya, I., Pantaleo, F. R., Paredes, J. M., Patricelli, B., Pecimotika, M., Peresano, M., Pérez-Romero, J., Persic, M., Petruk, O., Piano, G., Pietropaolo, E., Pirola, G., Pittori, C., Pohl, M., Ponti, G., Prandini, E., Principe, G., Priyadarshi, C., Pueschel, E., Pühlhofer, G., Pumo, M. L., Quirrenbach, A., Rando, R., Razzaque, S., Reichherzer, P., Reimer, A., Reimer, O., Renaud, M., Reposeur, T., Ribó, M., Richtler, T., Rico, J., Rieger, F., Rigoselli, M., Riitano, L., Rizi, V., Roache, E., Romano, P., Romeo, G., Rosado, J., Rowell, G., Rudak, B., Sadeh, I., Safi-Harb, S., Saha, L., Sailer, S., Sánchez-Conde, M., Sarkar, S., Satalecka, K., Saturni, F. G., Scherer, A., Schovánek, P., Schussler, F., Schwanke, U., Scuderi, S., Seglar-Arroyo, M., Sergijenko, O., Servillat, M., Shang, R-Y., Sharma, P., Siejkowski, H., Sliusar, V., Słowikowska, A., Sol, H., Specovius, A., Spencer, S. T., Spengler, G., Stamerra, A., Stanič, S., Starecki, T., Starling, R., Stolarczyk, T., Pereira, L. A. Stuani, Suda, Y., Suomijarvi, T., Sushch, I., Tajima, H., Tam, P-H. T., Tanaka, S. J., Tavecchio, F., Testa, V., Tian, W., Tibaldo, L., Torres, D. F., Tothill, N., Vallage, B., Vallania, P., van Eldik, C., van Scherpenberg, J., Vandenbroucke, J., Acosta, M. Vazquez, Vecchi, M., Vercellone, S., Verna, G., Viana, A., Vignatti, J., Vitale, V., Vodeb, V., Vorobiov, S., Vuillaume, T., Wagner, S. J., Walter, R., White, M., Wierzcholska, A., Will, M., Williams, D., Yang, L., Yoshida, T., Yoshikoshi, T., Zaharijas, G., Zampieri, L., Zavrtanik, D., Zavrtanik, M., Zhdanov, V. I., and Živec, M.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The local Cosmic Ray (CR) energy spectrum exhibits a spectral softening at energies around 3~PeV. Sources which are capable of accelerating hadrons to such energies are called hadronic PeVatrons. However, hadronic PeVatrons have not yet been firmly identified within the Galaxy. Several source classes, including Galactic Supernova Remnants (SNRs), have been proposed as PeVatron candidates. The potential to search for hadronic PeVatrons with the Cherenkov Telescope Array (CTA) is assessed. The focus is on the usage of very high energy $\gamma$-ray spectral signatures for the identification of PeVatrons. Assuming that SNRs can accelerate CRs up to knee energies, the number of Galactic SNRs which can be identified as PeVatrons with CTA is estimated within a model for the evolution of SNRs. Additionally, the potential of a follow-up observation strategy under moonlight conditions for PeVatron searches is investigated. Statistical methods for the identification of PeVatrons are introduced, and realistic Monte--Carlo simulations of the response of the CTA observatory to the emission spectra from hadronic PeVatrons are performed. Based on simulations of a simplified model for the evolution for SNRs, the detection of a $\gamma$-ray signal from in average 9 Galactic PeVatron SNRs is expected to result from the scan of the Galactic plane with CTA after 10 hours of exposure. CTA is also shown to have excellent potential to confirm these sources as PeVatrons in deep observations with $\mathcal{O}(100)$ hours of exposure per source., Comment: 34 pages, 16 figures, Accepted for publication in Astroparticle Physics
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- 2023
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31. The Online Observation Quality System Software Architecture for the ASTRI Mini-Array Project
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Parmiggiani, N., Bulgarelli, A., Baroncelli, L., Addis, A., Fioretti, V., Di Piano, A., Capalbi, M., Catalano, O., Conforti, V., Fiori, M., Gianotti, F., Iovenitti, S., Lucarelli, F., Maccarone, M. C., Mineo, T., Lombardi, S., Pastore, V., Russo, F., Sangiorgi, P., Scuderi, S., Tosti, G., Trifoglio, M., Zampieri, L., and Project, the ASTRI
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The ASTRI Mini-Array is an international collaboration led by the Italian National Institute for Astrophysics. This project aims to construct and operate an array of nine Imaging Atmospheric Cherenkov Telescopes to study gamma-ray sources at very high energy (TeV) and perform stellar intensity interferometry observations. We describe the software architecture and the technologies used to implement the Online Observation Quality System (OOQS) for the ASTRI Mini-Array project. The OOQS aims to execute data quality checks on the data acquired in real-time by the Cherenkov cameras and intensity interferometry instruments, and provides feedback to both the Central Control System and the Operator about abnormal conditions detected. The OOQS can notify other sub-systems, triggering their reaction to promptly correct anomalies. The results from the data quality analyses (e.g. camera plots, histograms, tables, and more) are stored in the Quality Archive for further investigation and they are summarised in reports available to the Operator. Once the OOQS results are stored, the operator can visualize them using the Human Machine Interface. The OOQS is designed to manage the high data rate generated by the instruments (up to 4.5 GB/s) and received from the Array Data Acquisition System through the Kafka service. The data are serialized and deserialized during the transmission using the Avro framework. The Slurm workload scheduler executes the analyses exploiting key features such as parallel analyses and scalability., Comment: 12 pages, 7 Figures. arXiv admin note: text overlap with arXiv:2108.04515
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- 2023
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32. The RTApipe framework for the gamma-ray real-time analysis software development
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Parmiggiani, N., Bulgarelli, A., Beneventano, D., Fioretti, V., Di Piano, A., Baroncelli, L., Addis, A., Tavani, M., Pittori, C., and Oya, I.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
In the multi-messenger era, coordinating observations between astronomical facilities is mandatory to study transient phenomena (e.g. Gamma-ray bursts) and is achieved by sharing information with the scientific community through networks such as the Gamma-ray Coordinates Network. The facilities usually develop real-time scientific analysis pipelines to detect transient events, alert the astrophysical community, and speed up the reaction time of science alerts received from other observatories. We present in this work the RTApipe framework, designed to facilitate the development of real-time scientific analysis pipelines for present and future gamma-ray observatories. This framework provides pipeline architecture and automatisms, allowing the researchers to focus on the scientific aspects and integrate existing science tools developed with different technologies. The pipelines automatically execute all the configured analyses during the data acquisition. This framework can be interfaced with science alerts networks to perform follow-up analysis of transient events shared by other facilities. The analyses are performed in parallel and can be prioritised. The workload is highly scalable on a cluster of machines. The framework provides the required services using containerisation technology for easy deployment. We present the RTA pipelines developed for the AGILE space mission and the prototype of the SAG system for the ground-based future Cherenkov Telescope Array observatory confirming that the RTApipe framework can be used to successfully develop pipelines for the gamma-ray observatories, both space and ground-based., Comment: 13 pages, 5 figures. Published on Astronomy and Computing
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- 2023
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33. Preliminary Results of a New Deep Learning Method to Detect and Localize GRBs in the AGILE/GRID Sky Maps
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Parmiggiani, N., Bulgarelli, A., Macaluso, A., Fioretti, V., Di Piano, A., Baroncelli, L., Addis, A., Landoni, M., Pittori, C., Verrecchia, F., Lucarelli, F., Giuliani, A., Longo, F., Beneventano, D., and Tavani, M.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
AGILE is an ASI space mission launched in 2007 to study X-ray and gamma-ray phenomena in the energy range from $\sim20$ keV to $\sim10$ GeV. The AGILE Team developed a real-time analysis pipeline for the fast detection of transient sources, and the follow-up of external science alerts received through networks such as the General Coordinates Network. We developed a new Deep Learning method for detecting and localizing Gamma-Ray Bursts (GRB) in the AGILE/GRID sky maps. We trained the model using sky maps with GRBs simulated in a radius of 20 degrees from the center of the map, which is larger than 99.5 \% of the error region present in the GRBWeb catalog. We also plan to apply this method to search for counterparts of gravitational wave events, which typically have a wider localization error region. The method comprises two Deep Learning models implemented with two Convolutional Neural Networks. The first model detects and filters sky maps containing a GRB, while the second model localizes its position. We trained and tested the models using simulated data. The detection model achieves an accuracy of 95.7 \%, and the localization model has a mean error lower than 0.8 degrees. We configured a Docker container with all the required software for data simulation and deployed it using the Amazon Web Service to calculate the p-value distribution under different conditions. With the p-value distribution, we can calculate the statistical significance of a detection., Comment: 4 pages, 1 figure, proceedings of the ADASS XXXII (2022) conference, to appear in ASP Conference Serie
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- 2023
34. Preliminary Results of a Deep Learning Anomaly Detection Method to Identify Gamma-Ray Bursts in the AGILE Anticoincidence System
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Parmiggiani, N., Bulgarelli, A., Ursi, A., Tavani, M., Macaluso, A., Di Piano, A., Fioretti, V., Baroncelli, L., Addis, A., and Pittori, C.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
AGILE is a space mission launched in 2007 to study X-ray and gamma-ray astronomy. The AGILE team developed real-time analysis pipelines to detect transient phenomena such as Gamma-Ray Bursts (GRBs) and to react to external science alerts received by other facilities. The AGILE anti-coincidence system (ACS) comprises five panels (four lateral and one on the top) that surround the AGILE detectors to reject background charged particles. It can also detect hard X-ray photons in the energy range 50 - 200 KeV. The acquisition of the ACS data produces a time series for each panel. These time series can be merged in a single multivariate time series (MTS). We present in this work a new Deep Learning model for GRBs detection in the MTSs, generated by the ACS, using an anomaly detection technique. The model is implemented with a Deep Convolutional Neural Network autoencoder architecture. We trained the model with an unsupervised learning algorithm using a dataset of MTSs randomly extracted from the AGILE ACS data. The reconstruction error of the autoencoder is used as the anomaly score to classify the MTS. If the anomaly score is higher than a predefined threshold, the MTS is flagged as a GRB. The trained model is evaluated using a list of MTSs containing GRBs. The tests confirmed the model's ability to detect transient events, providing a new promising technique to identify GRBs in the ACS data that can be implemented in the AGILE real-time analysis pipeline., Comment: 4 pages, 1 figure, proceedings of the ADASS XXXI (2021) conference, to appear in ASP Conference Serie
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- 2023
35. The AFISS web platform for the correlation of high-energy transient events
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Addis, A., Bulgarelli, A., Parmiggiani, N., Rodi, J., and Bazzano, A.
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
In the multi-messenger era, facilities share their results with the scientific community through networks such as the General Coordinates Network to study transient phenomena (e.g., Gamma-ray bursts) and implement real-time analysis pipelines to detect transient events, reacting to science alerts received from other observatories. The fast analysis of transient events is crucial for detecting counterparts of gravitational waves and neutrino candidate events. In this context, collecting scientific results from different high-energy satellites observing the same transient event represents a key step in improving the statistical significance of the high-energy candidate events. This project aims to develop a system and a web platform to share information and scientific results of transient events between high-energy satellites with INAF participation (AGILE, FERMI, INTEGRAL and SWIFT). The AFISS platform implements the COMET VO- Event broker and provides a web portal where the users visualize the list of transient events detected by multi-messenger facilities and received through the GCN. The web portal could show, for each event, a summary of the scientific results shared by the real-time analysis pipelines and a list of time-correlated transient events. In addition, the platform is ready to receive results from participating facilities on sub-threshold events (STE) that cannot be shared with the community due to the low statistical significance. If the platform finds a time correlation between two or more STEs, it can promote them to science alerts. The web interface shows the list of STEs with possible time correlation with other STEs or science alerts. The platform notifies the users with an email when a new transient event is received., Comment: 4 pages, 4 figures, Astronomical Data Analysis Software and System XXXII (31 October-4 November 2022)
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- 2023
36. The Gamma-Flash data acquisition system for observation of terrestrial gamma-ray flashes
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Bulgarelli, Andrea, Addis, Antonio, Aboudan, Alessio, Abu, Ismael, Andreani, Carla, Argan, Andrea, Campana, Riccardo, Calabretto, Paolo, Pittori, Carlotta, D'Amico, Fabio, Donnarumma, Imma, De Rosa, Adriano, Fuschino, Fabio, Gorini, Giuseppe, Levi, Giuseppe, Parmiggiani, Nicolò, Picozza, Piergiorgio, Polenta, Gianluca, Preziosi, Enrico, Senesi, Roberto, Ursi, Alessandro, Vagelli, Valerio, and Virgilli, Enrico
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Gamma-Flash is an Italian project funded by the Italian Space Agency (ASI) and led by the National Institute for Astrophysics (INAF), devoted to the observation and study of high-energy phenomena, such as terrestrial gamma-ray flashes and gamma-ray glows produced in the Earth's atmosphere during thunderstorms. The project's detectors and the data acquisition and control system (DACS) are placed at the "O. Vittori" observatory on the top of Mt. Cimone (Italy). Another payload will be placed on an aircraft for observations of thunderstorms in the air. This work presents the architecture of the data acquisition and control system and the data flow., Comment: 4 pages, 1 figure, Astronomical Data Analysis Software and System XXXII (2022)
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- 2023
37. The AGILEScience App to execute gamma-ray scientific analyses from mobile devices
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Bulgarelli, Andrea, Parmiggiani, Nicolò, Fioretti, Valentina, Baroncelli, Leonardo, Addis, Antonio, Di Piano, Ambra, Pittori, Carlotta, and Tavani, Marco
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
AGILE is a space mission launched in 2007 devoted to high-energy astrophysics. The AGILE Team is involved in the multi-messenger campaigns to send and receive science alerts about transient events in the shortest time possible. For this reason, the AGILE Team developed several real-time analysis pipelines to analyse data and follow-up external science alerts. However, the results obtained by these pipelines are preliminary and must be validated with manual analyses that are the bottleneck of the workflow. To speed up the scientific analysis performed by scientists, the AGILE Team developed the AGILEScience mobile application (for iOS and Android devices) that offers to the AGILE Team a password-protected section used to visualise the results of automated pipelines. We present in this contribution an improved functionality of the AGILEScience application that aims to enable the AGILE Team to execute a full scientific analysis using their mobile devices. When the analysis is completed, the system sends an email to notify the user that can visualise the results (e.g. plots, tables, and HTML pages) through the application. The possibility to perform scientific analysis from a mobile device enables the AGILE researchers to perform fast scientific analyses remotely to validate the preliminary results obtained with the automated pipelines. This workflow reduces the overall reaction time of the AGILE Team for the follow-up of transient phenomena., Comment: 4 pages, 4 figures, Astronomical Data Analysis Software and System XXXI (24-28 Ottobre 2021)
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- 2023
38. Duality transformations and the entanglement entropy of gauge theories
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Andrea Bulgarelli and Marco Panero
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Algorithms and Theoretical Developments ,Lattice Quantum Field Theory ,Other Lattice Field Theories ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract The study of entanglement in gauge theories is expected to provide insights into many fundamental phenomena, including confinement. However, calculations of quantities related to entanglement in gauge theories are limited by ambiguities that stem from the non-factorizability of the Hilbert space. In this work we study lattice gauge theories that admit a dual description in terms of spin models, for which the replica trick and Rényi entropies are well defined. In the first part of this work, we explicitly perform the duality transformation in a replica geometry, deriving the structure of a replica space for a gauge theory. Then, in the second part, we calculate, by means of Monte Carlo simulations, the entropic c-function of the ℤ 2 gauge theory in three spacetime dimensions, exploiting its dual description in terms of the three-dimensional Ising model.
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- 2024
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39. The Brain Imaging for Global Health (BRIGHT) Project: Longitudinal cohort study protocol [version 2; peer review: 2 approved]
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Sarah Lloyd-Fox, Bosiljka Milosavljevic, Sam McCann, Chiara Bulgarelli, Laura Katus, Giulia Ghillia, Maria Crespo-Llado, Ebrima Mbye, Tijan Fadera, Fabakary Njai, Luke Mason, Marta Perapoch-Amado, Omar Njie, Fatima Sosseh, Maria Rozhko, Ebou Touray, Mariama Saidykhan, Clare E. Elwell, Anna Blasi, and Sophie E. Moore
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Gambia ,UK ,infancy ,development ,undernutrition ,longitudinal ,eng ,Medicine - Abstract
There is a scarcity of prospective longitudinal research targeted at early postnatal life which maps developmental pathways of early-stage processing and brain specialisation in the context of early adversity. Follow up from infancy into the one-five year age range is key, as it constitutes a critical gap between infant and early childhood studies. Availability of portable neuroimaging (functional near infrared spectroscopy (fNIRS) and electroencephalography (EEG)) has enabled access to rural settings increasing the diversity of our sampling and broadening developmental research to include previously underrepresented ethnic-racial and geographical groups in low- and middle- income countries (LMICs). The primary objective of the Brain Imaging for Global Health (BRIGHT) project was to establish brain function - using longitudinal data from mother - for-age reference curves infant dyads living in the UK and rural Gambia and investigate the association between context-associated moderators and developmental trajectories across the first two years of life in The Gambia. In total, 265 participating families were seen during pregnancy, at 7–14 days, 1-, 5-, 8-, 12-, 18- and 24-months post-partum. An additional visit is now underway at 3–5 years to assess pre-school outcomes. The majority of our Gambian cohort live in poverty, but while resource-poor in many factors they commonly experience a rich and beneficial family and caregiving context with multigenerational care and a close-knit supportive community. Understanding the impact of different factors at play in such an environment (i.e., detrimental undernutrition versus beneficial multigenerational family support) will (i) improve the representativeness of models of general cognitive developmental pathways from birth, (ii) identify causal pathways of altered trajectories associated with early adversity at both individual and group level, and (iii) identify the context-associated moderators (i.e. social context) that protect development despite the presence of poverty-associated challenges. This will in turn contribute to the development of targeted interventions.
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- 2024
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40. First step results from a phase II study of a dendritic cell vaccine in glioblastoma patients (CombiG-vax)
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Laura Ridolfi, Lorena Gurrieri, Nada Riva, Jenny Bulgarelli, Francesco De Rosa, Massimo Guidoboni, Valentina Fausti, Nicoletta Ranallo, Sebastiano Calpona, Marcella Tazzari, Massimiliano Petrini, Anna Maria Granato, Elena Pancisi, Flavia Foca, Monia Dall’Agata, Isabella Bondi, Elena Amadori, Pietro Cortesi, Chiara Zani, Valentina Ancarani, Alessandro Gamboni, Antonio Polselli, Giuseppe Pasini, Daniela Bartolini, Giuseppe Maimone, Donatella Arpa, and Luigino Tosatto
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glioblastoma ,vaccine ,immunotherapy ,dendritic cell ,adoptive cell therapy ,radiochemotherapy ,Immunologic diseases. Allergy ,RC581-607 - Abstract
BackgroundGlioblastoma (GBM) is a poor prognosis grade 4 glioma. After surgical resection, the standard therapy consists of concurrent radiotherapy (RT) and temozolomide (TMZ) followed by TMZ alone. Our previous data on melanoma patients showed that Dendritic Cell vaccination (DCvax) could increase the amount of intratumoral-activated cytotoxic T lymphocytesMethodsThis is a single-arm, monocentric, phase II trial in two steps according to Simon’s design. The trial aims to evaluate progression-free survival (PFS) at three months and the safety of a DCvax integrated with standard therapy in resected GBM patients. DCvax administration begins after completion of RT-CTwith weekly administrations for 4 weeks, then is alternated monthly with TMZ cycles. The primary endpoints are PFS at three months and safety. One of the secondary objectives is to evaluate the immune response both in vitro and in vivo (DTH skin test).ResultsBy December 2022, the first pre-planned step of the study was concluded with the enrollment, treatment and follow up of 9 evaluable patients. Two patients had progressed within three months after leukapheresis, but none had experienced DCvax-related G3-4 toxicities Five patients experienced a positive DTH test towards KLH and one of these also towards autologous tumor homogenate. The median PFS from leukapheresis was 11.3 months and 12.2 months from surgery.ConclusionsThis combination therapy is well-tolerated, and the two endpoints required for the first step have been achieved. Therefore, the study will proceed to enroll the remaining 19 patients. (Eudract number: 2020-003755-15 https://www.clinicaltrialsregister.eu/ctr-search/trial/2020-003755-15/IT)
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- 2024
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41. Multi-wavelength study of the galactic PeVatron candidate LHAASO J2108+5157
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Abe, S., Aguasca-Cabot, A., Agudo, I., Crespo, N. Alvarez, Antonelli, L. A., Aramo, C., Arbet-Engels, A., Artero, M., Asano, K., Aubert, P., Baktash, A., Bamba, A., Larriva, A. Baquero, Baroncelli, L., de Almeida, U. Barres, Barrio, J. A., Batkovic, I., Baxter, J., González, J. Becerra, Bernardini, E., Bernardos, M. I., Medrano, J. Bernete, Berti, A., Bhattacharjee, P., Biederbeck, N., Bigongiari, C., Bissaldi, E., Blanch, O., Bordas, P., Buisson, C., Bulgarelli, A., Burelli, I., Buscemi, M., Cardillo, M., Caroff, S., Carosi, A., Cassol, F., Cauz, D., Ceribella, G., Chai, Y., Cheng, K., Chiavassa, A., Chikawa, M., Chytka, L., Cifuentes, A., Contreras, J. L., Cortina, J., Costantini, H., D'Amico, G., Dalchenko, M., De Angelis, A., de Lavergne, M. de Bony, De Lotto, B., de Menezes, R., Deleglise, G., Delgado, C., Mengual, J. Delgado, della Volpe, D., Dellaiera, M., Di Piano, A., Di Pierro, F., Di Tria, R., Di Venere, L., Díaz, C., Dominik, R. M., Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Elsässer, D., Emery, G., Escudero, J., Ramazani, V. Fallah, Ferrara, G., Fiasson, A., Coromina, L. Freixas, Fröse, S., Fukami, S., Fukazawa, Y., Garcia, E., López, R. Garcia, Gasparrini, D., Geyer, D., Paiva, J. Giesbrecht, Giglietto, N., Giordano, F., Giro, E., Gliwny, P., Godinovic, N., Grau, R., Green, D., Green, J., Gunji, S., Hackfeld, J., Hadasch, D., Hahn, A., Hashiyama, K., Hassan, T., Hayashi, K., Heckmann, L., Heller, M., Llorente, J. Herrera, Hirotani, K., Hoffmann, D., Horns, D., Houles, J., Hrabovsky, M., Hrupec, D., Hui, D., Hütten, M., Imazawa, R., Inada, T., Inome, Y., Ioka, K., Iori, M., Ishio, K., Iwamura, Y., Jacquemont, M., Martinez, I. Jimenez, Jurysek, J., Kagaya, M., Karas, V., Katagiri, H., Kataoka, J., Kerszberg, D., Kobayashi, Y., Kong, A., Kubo, H., Kushida, J., Lainez, M., Lamanna, G., Lamastra, A., Flour, T. Le, Linhoff, M., Longo, F., López-Coto, R., López-Moya, M., López-Oramas, A., Loporchio, S., Lorini, A., Luque-Escamilla, P. L., Majumdar, P., Makariev, M., Mandat, D., Manganaro, M., Manicò, G., Mannheim, K., Mariotti, M., Marquez, P., Marsella, G., Martí, J., Martinez, O., Martínez, G., Martínez, M., Marusevec, P., Mas-Aguilar, A., Maurin, G., Mazin, D., Guillen, E. Mestre, Micanovic, S., Miceli, D., Miener, T., Miranda, J. M., Mirzoyan, R., Mizuno, T., Gonzalez, M. Molero, Molina, E., Montaruli, T., Monteiro, I., Moralejo, A., Morcuende, D., Morselli, A., Mrakovcic, K., Murase, K., Nagai, A., Nakamori, T., Nickel, L., Nievas, M., Nishijima, K., Noda, K., Nosek, D., Nozaki, S., Ohishi, M., Ohtani, Y., Okazaki, N., Okumura, A., Orito, R., Otero-Santos, J., Palatiello, M., Paneque, D., Pantaleo, F. R., Paoletti, R., Paredes, J. M., Pavletić, L., Pech, M., Pecimotika, M., Pietropaolo, E., Pirola, G., Podobnik, F., Poireau, V., Polo, M., Pons, E., Prandini, E., Prast, J., Priyadarshi, C., Prouza, M., Rando, R., Rhode, W., Ribó, M., Rizi, V., Fernandez, G. Rodriguez, Saito, T., Sakurai, S., Sanchez, D. A., Šarić, T., Saturni, F. G., Scherpenberg, J., Schleicher, B., Schmuckermaier, F., Schubert, J. L., Schussler, F., Schweizer, T., Arroyo, M. Seglar, Sitarek, J., Sliusar, V., Spolon, A., Strišković, J., Strzys, M., Suda, Y., Sunada, Y., Tajima, H., Takahashi, M., Takahashi, H., Takata, J., Takeishi, R., Tam, P. H. T., Tanaka, S. J., Tateishi, D., Temnikov, P., Terada, Y., Terauchi, K., Terzic, T., Teshima, M., Tluczykont, M., Tokanai, F., Torres, D. F., Travnicek, P., Truzzi, S., Tutone, A., Uhlrich, G., Vacula, M., Acosta, M. Vázquez, Verguilov, V., Viale, I., Vigliano, A., Vigorito, C. F., Vitale, V., Voutsinas, G., Vovk, I., Vuillaume, T., Walter, R., Will, M., Yamamoto, T., Yamazaki, R., Yoshida, T., Yoshikoshi, T., Zywucka, N., Balbo, M., Eckert, D., and Tramacere, A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
LHAASO J2108+5157 is one of the few known unidentified Ultra-High-Energy (UHE) gamma-ray sources with no Very-High-Energy (VHE) counterpart, recently discovered by the LHAASO collaboration. We observed LHAASO J2108+5157 in the X-ray band with XMM-Newton in 2021 for a total of 3.8 hours and at TeV energies with the Large-Sized Telescope prototype (LST-1), yielding 49 hours of good quality data. In addition, we analyzed 12 years of Fermi-LAT data, to better constrain emission of its High-Energy (HE) counterpart 4FGL J2108.0+5155. We found an excess (3.7 sigma) in the LST-1 data at energies E > 3 TeV. Further analysis in the whole LST-1 energy range assuming a point-like source, resulted in a hint (2.2 sigma) of hard emission which can be described with a single power law with photon index Gamma = 1.6 +- 0.2 between 0.3 - 100 TeV. We did not find any significant extended emission which could be related to a Supernova Remnant (SNR) or Pulsar Wind Nebula (PWN) in the XMM-Newton data, which puts strong constraints on possible synchrotron emission of relativistic electrons. The LST-1 and LHAASO observations can be explained as inverse Compton-dominated leptonic emission of relativistic electrons with a cutoff energy of $100^{+70}_{-30}$ TeV. The low magnetic field in the source imposed by the X-ray upper limits on synchrotron emission is compatible with a hypothesis of a PWN or a TeV halo. The lack of a pulsar in the neighborhood of the UHE source is a challenge to the PWN/TeV-halo scenario. The UHE gamma rays can also be explained as $\pi^0$ decay-dominated hadronic emission due to interaction of relativistic protons with one of the two known molecular clouds in the direction of the source. The hard spectrum in the LST-1 band is compatible with protons escaping a shock around a middle-aged SNR because of their high low-energy cut-off., Comment: 26 pages, 9 figures, 5 tables; Astronomy and Astrophysics (accepted on 6 March 2023)
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- 2022
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42. The Athena X-ray Integral Field Unit: a consolidated design for the system requirement review of the preliminary definition phase
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Barret, Didier, Albouys, Vincent, Herder, Jan-Willem den, Piro, Luigi, Cappi, Massimo, Huovelin, Juhani, Kelley, Richard, Mas-Hesse, J. Miguel, Paltani, Stéphane, Rauw, Gregor, Rozanska, Agata, Svoboda, Jiri, Wilms, Joern, Yamasaki, Noriko, Audard, Marc, Bandler, Simon, Barbera, Marco, Barcons, Xavier, Bozzo, Enrico, Ceballos, Maria Teresa, Charles, Ivan, Costantini, Elisa, Dauser, Thomas, Decourchelle, Anne, Duband, Lionel, Duval, Jean-Marc, Fiore, Fabrizio, Gatti, Flavio, Goldwurm, Andrea, Hartog, Roland den, Jackson, Brian, Jonker, Peter, Kilbourne, Caroline, Korpela, Seppo, Macculi, Claudio, Mendez, Mariano, Mitsuda, Kazuhisa, Molendi, Silvano, Pajot, François, Pointecouteau, Etienne, Porter, Frederick, Pratt, Gabriel W., Prêle, Damien, Ravera, Laurent, Sato, Kosuke, Schaye, Joop, Shinozaki, Keisuke, Skup, Konrad, Soucek, Jan, Thibert, Tanguy, Vink, Jacco, Webb, Natalie, Chaoul, Laurence, Raulin, Desi, Simionescu, Aurora, Torrejon, Jose Miguel, Acero, Fabio, Branduardi-Raymont, Graziella, Ettori, Stefano, Finoguenov, Alexis, Grosso, Nicolas, Kaastra, Jelle, Mazzotta, Pasquale, Miller, Jon, Miniutti, Giovanni, Nicastro, Fabrizio, Sciortino, Salvatore, Yamaguchi, Hiroya, Beaumont, Sophie, Cucchetti, Edoardo, D'Andrea, Matteo, Eckart, Megan, Ferrando, Philippe, Kammoun, Elias, Lotti, Simone, Mesnager, Jean-Michel, Natalucci, Lorenzo, Peille, Philippe, de Plaa, Jelle, Ardellier, Florence, Argan, Andrea, Bellouard, Elise, Carron, Jérôme, Cavazzuti, Elisabetta, Fiorini, Mauro, Khosropanah, Pourya, Martin, Sylvain, Perry, James, Pinsard, Frederic, Pradines, Alice, Rigano, Manuela, Roelfsema, Peter, Schwander, Denis, Torrioli, Guido, Ullom, Joel, Vera, Isabel, Villegas, Eduardo Medinaceli, Zuchniak, Monika, Brachet, Frank, Cicero, Ugo Lo, Doriese, William, Durkin, Malcom, Fioretti, Valentina, Geoffray, Hervé, Jacques, Lionel, Kirsch, Christian, Smith, Stephen, Adams, Joseph, Gloaguen, Emilie, Hoogeveen, Ruud, van der Hulst, Paul, Kiviranta, Mikko, van der Kuur, Jan, Ledot, Aurélien, van Leeuwen, Bert-Joost, van Loon, Dennis, Lyautey, Bertrand, Parot, Yann, Sakai, Kazuhiro, van Weers, Henk, Abdoelkariem, Shariefa, Adam, Thomas, Adami, Christophe, Aicardi, Corinne, Akamatsu, Hiroki, Alonso, Pablo Eleazar Merino, Amato, Roberta, André, Jérôme, Angelinelli, Matteo, Anon-Cancela, Manuel, Anvar, Shebli, Atienza, Ricardo, Attard, Anthony, Auricchio, Natalia, Balado, Ana, Bancel, Florian, Barusso, Lorenzo Ferrari, Bernard, Vivian, Berrocal, Alicia, Blin, Sylvie, Bonino, Donata, Bonnet, François, Bonny, Patrick, Boorman, Peter, Boreux, Charles, Bounab, Ayoub, Boutelier, Martin, Boyce, Kevin, Brienza, Daniele, Bruijn, Marcel, Bulgarelli, Andrea, Calarco, Simona, Callanan, Paul, Camus, Thierry, Canourgues, Florent, Capobianco, Vito, Cardiel, Nicolas, Castellani, Florent, Cheatom, Oscar, Chervenak, James, Chiarello, Fabio, Clerc, Nicolas, Clerc, Laurent, Cobo, Beatriz, Coeur-Joly, Odile, Coleiro, Alexis, Colonges, Stéphane, Corcione, Leonardo, Coriat, Mickael, Coynel, Alexandre, Cuttaia, Francesco, D'Ai, Antonino, D'anca, Fabio, Dadina, Mauro, Daniel, Christophe, DeNigris, Natalie, Dercksen, Johannes, DiPirro, Michael, Doumayrou, Eric, Dubbeldam, Luc, Dupieux, Michel, Dupourqué, Simon, Durand, Jean Louis, Eckert, Dominique, Eiriz, Valvanera, Ercolani, Eric, Etcheverry, Christophe, Finkbeiner, Fred, Fiocchi, Mariateresa, Fossecave, Hervé, Franssen, Philippe, Frericks, Martin, Gabici, Stefano, Gant, Florent, Gao, Jian-Rong, Gastaldello, Fabio, Genolet, Ludovic, Ghizzardi, Simona, Gil, M Angeles Alcacera, Giovannini, Elisa, Godet, Olivier, Gomez-Elvira, Javier, Gonzalez, Manuel, Gonzalez, Raoul, Gottardi, Luciano, Granat, Dolorès, Gros, Michel, Guignard, Nicolas, Hieltjes, Paul, Hurtado, Adolfo Jesus, Irwin, Kent, Jacquey, Christian, Janiuk, Agnieszka, Jaubert, Jean, Jiménez, Maria, Jolly, Antoine, Jourdan, Thierry, Julien, Sabine, Kedziora, Bartosz, Korb, Andrew, Kreykenbohm, Ingo, König, Ole, Langer, Mathieu, Laudet, Philippe, Laurent, Philippe, Laurenza, Monica, Lesrel, Jean, Ligori, Sebastiano, Lorenz, Maximilian, Luminari, Alfredo, Maffei, Bruno, Maisonnave, Océane, Marelli, Lorenzo, Massonet, Didier, Maussang, Irwin, Melchor, Alejandro Gonzalo, Mer, Isabelle Le, Michalski, Lea, Millerioux, Jean-Pierre, Mineo, Teresa, Minervini, Gabriele, Molin, Alexeï, Monestes, David, Montinaro, Nicola, Mot, Baptiste, Murat, David, Nagayoshi, Kenichiro, Nazé, Yaël, Noguès, Loïc, Pailot, Damien, Panessa, Francesca, Parodi, Luigi, Petit, Pascal, Piconcelli, Enrico, Pinto, Ciro, Plaza, Jose Miguel Encinas, Poyatos, David, Prouvé, Thomas, Ptak, Andy, Puccetti, Simonetta, Puccio, Elena, Ramon, Pascale, Reina, Manuel, Rioland, Guillaume, Rodriguez, Louis, Roig, Anton, Rollet, Bertrand, Roncarelli, Mauro, Roudil, Gilles, Rudnicki, Tomasz, Sanisidro, Julien, Sciortino, Luisa, Silva, Vitor, Sordet, Michael, Soto-Aguilar, Javier, Spizzi, Pierre, Surace, Christian, Sánchez, Miguel Fernández, Taralli, Emanuele, Terrasa, Guilhem, Terrier, Régis, Todaro, Michela, Ubertini, Pietro, Uslenghi, Michela, de Vaate, Jan Geralt Bij, Vaccaro, Davide, Varisco, Salvatore, Varnière, Peggy, Vibert, Laurent, Vidriales, María, Villa, Fabrizio, Vodopivec, Boris Martin, Volpe, Angela, de Vries, Cor, Wakeham, Nicholas, Walmsley, Gavin, Wise, Michael, de Wit, Martin, and Woźniak, Grzegorz
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The Athena X-ray Integral Unit (X-IFU) is the high resolution X-ray spectrometer, studied since 2015 for flying in the mid-30s on the Athena space X-ray Observatory, a versatile observatory designed to address the Hot and Energetic Universe science theme, selected in November 2013 by the Survey Science Committee. Based on a large format array of Transition Edge Sensors (TES), it aims to provide spatially resolved X-ray spectroscopy, with a spectral resolution of 2.5 eV (up to 7 keV) over an hexagonal field of view of 5 arc minutes (equivalent diameter). The X-IFU entered its System Requirement Review (SRR) in June 2022, at about the same time when ESA called for an overall X-IFU redesign (including the X-IFU cryostat and the cooling chain), due to an unanticipated cost overrun of Athena. In this paper, after illustrating the breakthrough capabilities of the X-IFU, we describe the instrument as presented at its SRR, browsing through all the subsystems and associated requirements. We then show the instrument budgets, with a particular emphasis on the anticipated budgets of some of its key performance parameters. Finally we briefly discuss on the ongoing key technology demonstration activities, the calibration and the activities foreseen in the X-IFU Instrument Science Center, and touch on communication and outreach activities, the consortium organisation, and finally on the life cycle assessment of X-IFU aiming at minimising the environmental footprint, associated with the development of the instrument. Thanks to the studies conducted so far on X-IFU, it is expected that along the design-to-cost exercise requested by ESA, the X-IFU will maintain flagship capabilities in spatially resolved high resolution X-ray spectroscopy, enabling most of the original X-IFU related scientific objectives of the Athena mission to be retained. (abridged)., Comment: 48 pages, 29 figures, Accepted for publication in Experimental Astronomy with minor editing
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- 2022
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43. The ASTRI Mini-Array of Cherenkov Telescopes at the Observatorio del Teide
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S., Scuderi, A., Giuliani, G., Pareschi, G., Tosti, O., Catalano, E., Amato, A., Antonelli L., J., Becerra Gonzáles, G., Bellassai, Bigongiari, B., Biondo, M., Böttcher, G., Bonanno, G., Bonnoli, P., Bruno, A., Bulgarelli, R., Canestrari, M., Capalbi, P., Caraveo, M., Cardillo, V., Conforti, G., Contino, M., Corpora, A., Costa, G., Cusumano, A., D'Aí, E., de Gouveia Dal Pino, R., Della Ceca, D., Escribano Rodriguez E. Falceta Gonçalves, C., Fermino, M., Fiori, V., Fioretti, M., Fiorini, S., Gallozzi, C., Gargano, S., Garozzo, S., Germani, A., Ghedina, F., Gianotti, S., Giarrusso, R., Gimenes, V., Giordano, A., Grillo, C., Grivel Gelly, D., Impiombato, F., Incardona, S., Incorvaia, S., Iovenitti, A., La Barbera, N., La Palombara, V., La Parola, A., Lamastra, L., Lessio, G., Leto, F., Lo Gerfo, M., Lodi, S., Lombardi, F., Longo, F., Lucarelli, C., Maccarone M., D., Marano, E., Martinetti, S., Mereghetti, A., Micciché, R., Millul, T., Mineo, D., Mollica, G., Morlino, A., Morselli, G., Naletto, G., Nicotra, A., Pagliaro, N., Parmiggiani, G., Piano, F., Pintore, E., Poretti, B., Olmi, G., Rodeghiero, G., Rodriguez Fernandez, P., Romano, G., Romeo, F., Russo, P., Sangiorgi, G., Saturni F., H., Schwarz J., Sciacca, G., Sironi, G., Sottile, A., Stamerra, G., Tagliaferri, V., Testa, G., Umana, M., Uslenghi, S., Vercellone, L., Zampieri, and R, Zanmar Sanchez
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The ASTRI Mini-Array (MA) is an INAF project to build and operate a facility to study astronomical sources emitting at very high-energy in the TeV spectral band. The ASTRI MA consists of a group of nine innovative Imaging Atmospheric Cherenkov telescopes. The telescopes will be installed at the Teide Astronomical Observatory of the Instituto de Astrofisica de Canarias (IAC) in Tenerife (Canary Islands, Spain) on the basis of a host agreement with INAF. Thanks to its expected overall performance, better than those of current Cherenkov telescopes' arrays for energies above \sim 5 TeV and up to 100 TeV and beyond, the ASTRI MA will represent an important instrument to perform deep observations of the Galactic and extra-Galactic sky at these energies., Comment: 19 pages, 22 figures
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- 2022
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44. Galactic Observatory Science with the ASTRI Mini-Array at the Observatorio del Teide
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D'Aì, A., Amato, E., Burtovoi, A., Compagnino, A. A., Fiori, M., Giuliani, A., La Palombara, N., Paizis, A., Piano, G., Saturni, F. G., Tutone, A., Belfiore, A., Cardillo, M., Crestan, S., Cusumano, G., Della Valle, M., Del Santo, M., La Barbera, A., La Parola, V., Lombardi, S., Mereghetti, S., Morlino, G., Pintore, F., Romano, P., Vercellone, S., Antonelli, A., Arcaro, C., Bigongiari, C., Böettcher, M., Bruno, P., Bulgarelli, A., Conforti, V., Costa, A., Pino, E. de Gouveia Dal, Fioretti, V., Germani, S., Ghedina, A., Gianotti, F., Giordano, V., Incardona, F., Leto, G., Longo, F., Oramas, A. López, Lucarelli, F., Olmi, B., Pagliaro, A., Parmiggiani, N., Romeo, G., Stamerra, A., Testa, V., Tosti, G., Umana, G., Zampieri, L., Caraveo, P., and Pareschi, G.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The ASTRI (Astrofisica con Specchi a Tecnologia Replicante Italiana) Mini-Array will be composed of nine imaging atmospheric Cherenkov telescopes at the Observatorio del Teide site. The array will be best suited for astrophysical observations in the 0.3-200 TeV range with an angular resolution of few arc-minutes and an energy resolution of 10-15\%. A core-science programme in the first four years will be devoted to a limited number of key targets, addressing the most important open scientific questions in the very-high energy domain. At the same time, thanks to a wide field of view of about 10 degrees, ASTRI Mini-Array will observe many additional field sources, which will constitute the basis for the long-term observatory programme that will eventually cover all the accessible sky. In this paper, we review different astrophysical Galactic environments, e.g. pulsar wind nebulae, supernova remnants, and gamma-ray binaries, and show the results from a set of ASTRI Mini-Array simulations of some of these field sources made to highlight the expected performance of the array (even at large offset angles) and the important additional observatory science that will complement the core-science program., Comment: Accepted for publication in Journal of High-Energy Astrophysics
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- 2022
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45. ASTRI Mini-Array Core Science at the Observatorio del Teide
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Vercellone, S., Bigongiari, C., Burtovoi, A., Cardillo, M., Catalano, O., Franceschini, A., Lombardi, S., Nava, L., Pintore, F., Stamerra, A., Tavecchio, F., Zampieri, L., Batista, R. Alves, Amato, E., Antonelli, L. A., Arcaro, C., Gonzalez, J. Becerra, Bonnoli, G., Bottcher, M., Brunetti, G., Compagnino, A. A., Crestan, S., Ai, A. D, Fiori, M., Galanti, G., Giuliani, A., Pino, E. M. de Gouveia Dal, Green, J. G., Lamastra, A., Landoni, M., Lucarelli, F., Morlino, G., Olmi, B., Peretti, E., Piano, G., Ponti, G., Poretti, E., Romano, P., Saturni, F. G., Scuderi, S., Tutone, A., Umana, G., Acosta-Pulido, J. A., Barai, P., Bonanno, A., Bonanno, G., Bruno, P., Bulgarelli, A., Conforti, V., Costa, A., Cusumano, G., Del Santo, M., del Valle, M. V., Della Ceca, R., Falceta-Goncalves, D. A., Fioretti, V., Germani, S., Garcia-Lopez, R. J., Ghedina, A., Giordano, V., Kreter, M., Incardona, F., Iovenitti, S., La Barbera, A., La Palombara, N., La Parola, V., Leto, G., Longo, F., Lopez-Oramas, A., Maccarone, M. C., Mereghetti, S., Millul, R., Naletto, G., Pagliaro, A., Parmiggiani, N., Righi, C., Rodriguez-Ramirez, J. C., Romeo, G., Sangiorgi, P., de Lima, R. Santos, Tagliaferri, G., Testa, V., Tosti, G., Acosta, M. Vazquez, Zywucka, N., Caraveo, P. A., and Pareschi, G.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The ASTRI (Astrofisica con Specchi a Tecnologia Replicante Italiana) Project led by the Italian National Institute for Astrophysics (INAF) is developing and will deploy at the Observatorio del Teide a mini-array (ASTRI Mini-Array) composed of nine telescopes similar to the small-size dual-mirror Schwarzschild-Couder telescope (ASTRI-Horn) currently operating on the slopes of Mt. Etna in Sicily. The ASTRI Mini-Array will surpass the current Cherenkov telescope array differential sensitivity above a few tera-electronvolt (TeV), extending the energy band well above hundreds of TeV. This will allow us to explore a new window of the electromagnetic spectrum, by convolving the sensitivity performance with excellent angular and energy resolution figures. In this paper we describe the Core Science that we will address during the first four years of operation, providing examples of the breakthrough results that we will obtain when dealing with current open questions, such as the acceleration of cosmic rays, cosmology and fundamental physics and the new window, for the TeV energy band, of the time-domain astrophysics., Comment: Published in Journal of High Energy Astrophysics. 46 Figures, 7 Tables
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- 2022
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46. Extragalactic Observatory Science with the ASTRI Mini-Array at the Observatorio del Teide
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Saturni, F. G., Arcaro, C. H. E., Balmaverde, B., González, J. Becerra, Caccianiga, A., Capalbi, M., Lamastra, A., Lombardi, S., Lucarelli, F., Batista, R. Alves, Antonelli, L. A., Pino, E. M. de Gouveia Dal, Della Ceca, R., Green, J. G., Pagliaro, A., Righi, C., Tavecchio, F., Vercellone, S., Wolter, A., Amato, E., Bigongiari, C., Böttcher, M., Brunetti, G., Bruno, P., Bulgarelli, A., Cardillo, M., Conforti, V., Costa, A., Cusumano, G., Fioretti, V., Germani, S., Ghedina, A., Gianotti, F., Giordano, V., Giuliani, A., Incardona, F., La Barbera, A., Leto, G., Longo, F., Morlino, G., Olmi, B., Parmiggiani, N., Romano, P., Romeo, G., Stamerra, A., Tagliaferri, G., Testa, V., Tosti, G., Caraveo, P. A., and Pareschi, G.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The ASTRI Mini-Array is a next-generation system of nine imaging atmospheric Cherenkov telescopes that is going to be built at the Observatorio del Teide site. After a first phase, in which the instrument will be operated as an experiment prioritizing a schedule of primary science cases, an observatory phase is foreseen in which other significant targets will be pointed. We focus on the observational feasibility of extragalactic sources and on astrophysical processes that best complement and expand the ASTRI Mini-Array core science, presenting the most relevant examples that are at reach of detection over long-term time scales and whose observation can provide breakthrough achievements in the very-high energy extragalactic science. Such examples cover a wide range of $\gamma$-ray emitters, including the study of AGN low states in the multi-TeV energy range, the possible detection of Seyfert galaxies with long exposures and the searches of dark matter lines above 10 TeV. Simulations of the presented objects show that the instrument performance will be competitive at multi-TeV energies with respect to current arrays of Cherenkov telescopes., Comment: 27 pages, 10 figures, 7 tables, published on JHEAp
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- 2022
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47. Intersurgeon variations in postoperative length of stay after video-assisted thoracoscopic surgery lobectomyCentral MessagePerspective
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Jonathan Zini, Gabriel Dayan, MD, Maxime Têtu, Toni Kfouri, Luciano Bulgarelli Maqueda, MD, Elias Abdulnour, MD, Pasquale Ferraro, MD, Pierre Ghosn, MD, Edwin Lafontaine, MD, Jocelyne Martin, MD, Basil Nasir, MD, and Moishe Liberman, MD, PhD
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video-assisted thoracoscopic surgery ,lobectomy ,postoperative ,length of stay ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 ,Surgery ,RD1-811 - Abstract
Objectives: To identify factors associated with prolonged postoperative length of stay (LOS) after VATS lobectomy (VATS-L), explore potential intersurgeon variation in LOS and ascertain whether or not early discharge influences hospital readmission rates. Methods: We conducted a retrospective analysis of patients who underwent VATS-L at a single academic center between 2018 and 2021. Each VATS lobectomy procedure was performed by 1 of 7 experienced thoracic surgeons. The primary end point of interest was prolonged LOS, defined as an index LOS >3 days. Results: Among 1006 patients who underwent VATS lobectomy, 632 (63%) had a prolonged LOS. On multivariate analysis, the factors independently associated with prolonged LOS were: surgeon (P 3, and prior ipsilateral thoracic surgery or sternotomy. There was no association between LOS ≤3 days and hospital readmission (20 [5.3%] vs 39 [5.9%]; OR, 0.88; 95% CI, 0.50-1.53). Conclusions: An intersurgeon variation in postoperative LOS after VATS-L exists and is independent of patient baseline characteristics or perioperative complications. This variation seems to be more closely related to differences in postoperative management and discharge practices rather than to surgical quality. Postoperative discharge within 3 days is safe and does not increase hospital readmissions.
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- 2024
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48. The Monitoring Logging and Alarm System of the ASTRI Mini-Array gamma-ray air-Cherenkov experiment at the Observatorio del Teide
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Incardona, Federico, Costa, Alessandro, Munari, Kevin, Gambadoro, Salvatore, Germani, Stefano, Bruno, Pietro, Bulgarelli, Andrea, Conforti, Vito, Gianotti, Fulvio, Grillo, Alessandro, Pastore, Valerio, Russo, Federico, Schwarz, Joseph, Tosti, Gino, Cavalieri, Salvatore, and Project, for the ASTRI
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The ASTRI Mini-Array is a project for the Cherenkov astronomy in the TeV energy range. ASTRI Mini-Array consists of nine Imaging Atmospheric Cherenkov telescopes located at the Teide Observatory (Canarias Islands). Large volumes of monitoring and logging data result from the operation of a large-scale astrophysical observatory. In the last few years, several "Big Data" technologies have been developed to deal with such volumes of data, especially in the Internet of Things (IoT) framework. We present the Monitoring, Logging, and Alarm (MLA) system for the ASTRI Mini-Array aimed at supporting the analysis of scientific data and improving the operational activities of the telescope facility. The MLA system was designed and built considering the latest software tools and concepts coming from Big Data and IoT to respond to the challenges posed by the operation of the array. A particular relevance has been given to satisfying the reliability, availability, and maintainability requirements towards all the array sub-systems and auxiliary devices. The system architecture has been designed to scale up with the number of devices to be monitored and with the number of software components to be considered in the distributed logging system.
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- 2022
49. AGILE Observations of GRB 220101A: A 'New Year's Burst' with an Exceptionally Huge Energy Release
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Ursi, Alessandro, Romani, Marco, Piano, Giovanni, Verrecchia, Francesco, Longo, Francesco, Pittori, Carlotta, Tavani, Marco, Bulgarelli, Andrea, Cardillo, Martina, Casentini, Claudio, Cattaneo, Paolo Walter, Costa, Enrico, Feroci, Marco, Fioretti, Valentina, Foffano, Luca, Lucarelli, Fabrizio, Marisaldi, Martino, Morselli, Aldo, Pacciani, Luigi, Parmiggiani, Nicolò, Tempesta, Patrizio, Trois, Alessio, and Vercellone, Stefano
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report the AGILE observations of GRB 220101A, which took place at the beginning of 1st January 2022 and was recognized as one of the most energetic gamma-ray bursts (GRBs) ever detected since their discovery. The AGILE satellite acquired interesting data concerning the prompt phase of this burst, providing an overall temporal and spectral description of the event in a wide energy range, from tens of keV to tens of MeV. Dividing the prompt emission into three main intervals, we notice an interesting spectral evolution, featuring a notable hardening of the spectrum in the central part of the burst. The average fluxes encountered in the different time intervals are relatively moderate, with respect to those of other remarkable bursts, and the overall fluence exhibits a quite ordinary value among the GRBs detected by MCAL. However, GRB 220101A is the second farthest event detected by AGILE, and the burst with the highest isotropic equivalent energy of the whole MCAL GRB sample, releasing E_iso=2.54x10^54 erg and exhibiting an isotropic luminosity of L_iso=2.34x10^52 erg/s (both in the 400 keV - 10 MeV energy range). We also analyzed the first 10^6 s of the afterglow phase, using the publicly available Swift XRT data, carrying out a theoretical analysis of the afterglow, based on the forward shock model. We notice that GRB 220101A is with high probability surrounded with a wind-like density medium, and that the energy carried by the initial shock shall be a fraction of the total E_iso, presumably near 50%., Comment: 16 pages, 9 figures, 4 tables
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- 2022
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50. The Second Catalog of Interplanetary Network Localizations of Konus Short Duration Gamma-Ray Bursts
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Svinkin, D., Hurley, K., Ridnaia, A., Lysenko, A., Frederiks, D., Golenetskii, S., Tsvetkova, A., Ulanov, M., Kokomov, A., Cline, T. L., Mitrofanov, I., Golovin, D., Kozyrev, A., Litvak, M., Sanin, A., Goldstein, A., Briggs, M. S., Wilson-Hodge, C., Burns, E., von Kienlin, A., Zhang, X. -L., Rau, A., Savchenko, V., Bozzo, E., Ferrigno, C., Barthelmy, S., Cummings, J., Krimm, H., Palmer, D. M., Tohuvavohu, A., Yamaoka, K., Ohno, M., Fukazawa, Y., Hanabata, Y., Takahashi, T., Tashiro, M., Terada, Y., Murakami, T., Makishima, K., Boynton, W., Fellows, C. W., Harshman, K. P., Enos, H., Starr, R., Goldsten, J., Gold, R., Ursi, A., Tavani, M., Bulgarelli, A., Casentini, C., Del Monte, E., Evangelista, Y., Galli, M., Longo, F., Marisaldi, M., Parmiggiani, N., Pittori, C., Romani, M., Verrecchia, F., Smith, D. M., Hajdas, W., Xiao, S., Cai, C., Yi, Q. B., Zhang, Y. Q., Xiong, S. L., Li, X. B., Huang, Y., Li, C. K., Zhang, S. N., Song, L. M., Liu, C. Z., Li, X. Q., Peng, W. X., and Martinez-Castellanos, I.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present the catalog of Interplanetary Network (IPN) localizations for 199 short-duration gamma-ray bursts (sGRBs) detected by the Konus-Wind (KW) experiment between 2011 January 1 and 2021 August 31, which extends the initial sample of IPN localized KW sGRBs (arXiv:1301.3740) to 495 events. We present the most comprehensive IPN localization data on these events, including probability sky maps in HEALPix format., Comment: Published in ApJS
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- 2022
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