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1. The association of spirometric small airways obstruction with respiratory symptoms, cardiometabolic diseases, and quality of life: results from the Burden of Obstructive Lung Disease (BOLD) study

Author

Knox-Brown, Ben, Patel, Jaymini, Potts, James, Ahmed, Rana, Aquart-Stewart, Althea, Barbara, Cristina, Buist, A. Sonia, Cherkaski, Hamid Hacene, Denguezli, Meriam, Elbiaze, Mohammed, Erhabor, Gregory E., Franssen, Frits M. E., Al Ghobain, Mohammed, Gislason, Thorarinn, Janson, Christer, Kocabaş, Ali, Mannino, David, Marks, Guy, Mortimer, Kevin, Nafees, Asaad Ahmed, Obaseki, Daniel, Paraguas, Stefanni Nonna M., Loh, Li Cher, Rashid, Abdul, Salvi, Sundeep, Seemungal, Terence, Studnicka, Michael, Tan, Wan C., Wouters, Emiel F. M., Abozid, Hazim, Mueller, Alexander, Burney, Peter, and Amaral, Andre F. S.

Published
2023
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2. Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study

Author

Hafizi, Hasan, Aliko, Anila, Bardhi, Donika, Tafa, Holta, Thanasi, Natasha, Mezini, Arian, Teferici, Alma, Todri, Dafina, Nikolla, Jolanda, Kazasi, Rezarta, Cherkaski, Hamid Hacene, Bengrait, Amira, Haddad, Tabarek, Zgaoula, Ibtissem, Ghit, Maamar, Roubhia, Abdelhamid, Boudra, Soumaya, Atoui, Feryal, Yakoubi, Randa, Benali, Rachid, Bencheikh, Abdelghani, Ait-Khaled, Nadia, Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Studnicka, Michael, Dawes, Torkil, Lamprecht, Bernd, Schirhofer, Lea, Islam, Akramul, Ahmed, Syed Masud, Islam, Shayla, Islam, Qazi Shafayetul, Mesbah-Ul-Haque, Chowdhury, Tridib Roy, Chatterjee, Sukantha Kumar, Mia, Dulal, Chandra Das, Shyamal, Rahman, Mizanur, Islam, Nazrul, Uddin, Shahaz, Islam, Nurul, Khatun, Luiza, Parvin, Monira, Khan, Abdul Awal, Islam, Maidul, Lawin, Herve, Kpangon, Arsene, Kpossou, Karl, Agodokpessi, Gildas, Ayelo, Paul, Fayomi, Benjamin, Mbatchou, Bertrand, Ashu, Atongno Humphrey, Tan, Wan C., Wang, Wen, Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jin-ping, Zhou, Yumin, Jogi, Rain, Laja, Hendrik, Ulst, Katrin, Zobel, Vappu, Lill, Toomas-Julius, Adegnika, Ayola Akim, Welte, Tobias, Bodemann, Isabelle, Geldmacher, Henning, SchwedaLinow, Alexandra, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jorundsdottir, Kristin, Lovisa Gudmundsdottir, Gudmundsdottir, Sigrun, Gudmundsson, Gunnar, Rao, Mahesh, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Raphael, Jonelle, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Katkar, Sunil, Kadam, Milind, Dhanawade, Rupesh, Ghurup, Umesh, Juvekar, Sanjay, Hirve, Siddhi, Sambhudas, Somnath, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Arati, Umap, Archana, Shelar, Nitin, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Gawhane, Ashleshsa, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Madas, Sapna, Aquart-Stewart, Althea, Aikman, Akosua Francia, Sooronbaev, Talant M., Estebesova, Bermet M., Akmatalieva, Meerim, Usenbaeva, Saadat, Kydyrova, Jypara, Bostonova, Eliza, Sheraliev, Ulan, Marajapov, Nuridin, Toktogulova, Nurgul, Emilov, Berik, Azilova, Toktogul, Beishekeeva, Gulnara, Dononbaeva, Nasyikat, Tabyshova, Aijamal, Mortimer, Kevin, Nyapigoti, Wezzie, Mwangoka, Ernest, Kambwili, Mayamiko, Chipeta, Martha, Banda, Gloria, Mkandawire, Suzgo, Banda, Justice, Loh, Li-Cher, Rashid, Abdul, Sholehah, Siti, Benjelloun, Mohamed C., Nejjari, Chakib, Elbiaze, Mohamed, El Rhazi, Karima, Wouters, E.F.M., Wesseling, G.J., Obaseki, Daniel, Erhabor, Gregory, Awopeju, Olayemi, Adewole, Olufemi, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Nafees, Asaad A., Irfan, Muhammad, Fatmi, Zafar, Zahidie, Aysha, Shaukat, Natasha, Iqbal, Meesha, Idolor, Luisito F., de Guia, Teresita S., Francisco, Norberto A., Roa, Camilo C., Ayuyao, Fernando G., Tady, Cecil Z., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Jr., Reyes, Maria Teresita N., Dantes, Renato B., Amarillo, Lourdes, Berratio, Lakan U., Fernandez, Lenora C., Garcia, Gerard S., Naval, Sullian S., Reyes, Thessa, Roa, Camilo C., Jr., Sanchez, Flordeliza, Simpao, Leander P., Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Pajak, Andrzej, Skucha, Wojciech, Szczeklik, Andrzej, Twardowska, Magda, Barbara, Cristina, Rodrigues, Fatima, Dias, Herminia, Cardoso, Joao, Almeida, João, Matos, Maria Joao, Simão, Paula, Santos, Moutinho, Ferreira, Reis, Al Ghobain, M., Alorainy, H., El-Hamad, E., Al Hajjaj, M., Hashi, A., Dela, R., Fanuncio, R., Doloriel, E., Marciano, I., Safia, L., Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gunasekera, Kirthi, Wickremasinghe, Rajitha, Elsony, Asma, Elsadig, Hana A., Osman, Nada Bakery, Noory, Bandar Salah, Mohamed, Monjda Awad, Akasha Ahmed Osman, Hasab Alrasoul, Moham ed Elhassan, Namarig, El Zain, Abdel Mu’is, Mohamaden, Marwa Mohamed, Khalifa, Suhaiba, Elhadi, Mahmoud, Hassan, Mohand, Abdelmonam, Dalia, Janson, Christer, Olafsdottir, Inga Sif, Nisser, Katarina, SpetzNystrom, Ulrike, Hagg, Gunilla, Lund, GunMarie, Seemungal, Terence, Lutchmansingh, Fallon, Conyette, Liane, Harrabi, Imed, Denguezli, Myriam, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Kocabas, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Burney, Peter G.J., Gnatiuc, Louisa, Azar, Hadia, Patel, Jaymini, Amor, Caron, Potts, James, Tumilty, Michael, McLean, Fiona, Dudhaiya, Risha, Buist, A. Sonia, McBurnie, Mary Ann, Vollmer, William M., Gillespie, Suzanne, Sullivan, Sean, Lee, Todd A., Weiss, Kevin B., Jensen, Robert L., Crapo, Robert, Enright, Paul, Mannino, David M., Cain, John, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Abozid, Hazim, Burney, Peter, Hartl, Sylvia, Breyer-Kohansal, Robab, Al Ghobain, Mohammed, Denguezli, Meriam, Loh, Li Cher, Paraguas, Stefanni Nonna, Franssen, Frits M.E., Mannino, David, Anand, Mahesh Padukudru, Buist, Sonia, El Sony, Asma, Breyer, Marie-Kathrin, Burghuber, Otto C., Wouters, Emiel F.M., and Amaral, Andre F.S.

Published
2024
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3. Occupational exposures and incidence of chronic bronchitis and related symptoms over two decades : the European Community Respiratory Health Survey

Author

Lytras, Theodore, Kogevinas, Manolis, Kromhout, Hans, Carsin, Anne-Elie, Antó, Josep Maria, Bentouhami, Hayat, Weyler, Joost, Heinrich, Joachim, Nowak, Dennis, Urrutia, Isabel, Martínez-Moratalla, Jesús, Gullón, José Antonio, Vega, Antonio Pereira, Semjen, Chantal Raherison, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Villani, Simona, Gíslason, Thorarinn, Svanes, Øistein, Holm, Mathias, Forsberg, Bertil, Norbäck, Dan, Mehta, Amar J, Probst-Hensch, Nicole, Benke, Geza, Jogi, Rain, Torén, Kjell, Sigsgaard, Torben, Schlünssen, Vivi, Olivieri, Mario, Blanc, Paul D, Watkins, John, Bono, Roberto, Buist, A. Sonia, Vermeulen, Roel, Jarvis, Deborah, and Zock, Jan-Paul

Published
2019

4. Overdiagnosis of COPD in Subjects With Unobstructed Spirometry: A BOLD Analysis

Author

Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jingping, Zhou, Yumin, Kocabaş, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Studnicka, Michael, Dawes, Torkil, Lamprecht, Bernd, Sator, Lea, Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jörundsdottir, Kristin, Gudmundsdottir, Lovisa, Gudmundsdottir, Sigrun, Gundmundsson, Gunnar, Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Pajak, Andrzej, Skucha, Wojciech, Szczeklik, Andrzej, Twardowska, Magda, Welte, Tobias, Bodemann, Isabelle, Geldmacher, Henning, Schweda-Linow, Alexandra, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Tan, Wan C., Wang, Wen, Mannino, David M., Cain, John, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Dantes, Renato B., Amarillo, Lourdes, Berratio, Lakan U., Fernandez, Lenora C., Francisco, Norberto A., Garcia, Gerard S., de Guia, Teresita S., Idolor, Luisito F., Naval, Sullian S., Reyes, Thessa, Roa, Camilo C., Jr., Sanchez, Ma. Flordeliza, Simpao, Leander P., Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Burney, Peter G.J., Amor, Caron, Potts, James, Tumilty, Michael, McLean, Fiona, Wouters, E.F.M., Wesseling, G.J., Bárbara, Cristina, Rodrigues, Fátima, Dias, Hermínia, Cardoso, João, Almeida, João, Matos, Maria João, Simão, Paula, Santos, Moutinho, Ferreira, Reis, Janson, Christer, Olafsdottir, Inga Sif, Nisser, Katarina, Spetz-Nyström, Ulrike, Hägg, Gunilla, Lund, Gun-Marie, Jõgi, Rain, Laja, Hendrik, Ulst, Katrin, Zobel, Vappu, Lill, Toomas-Julius, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Raphael, Jonelle, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Katkar, Sunil, Kadam, Milind, Dhanawade, Rupesh, Ghurup, Umesh, Harrabi, Imed, Denguezli, Myriam, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Roa, Camilo C., Ayuyao, Fernando G., Tady, Cecil Z., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Jr., Reyes, Maria Teresita N., Juvekar, Sanjay, Hirve, Siddhi, Sambhudas, Somnath, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Arati, Umap, Archana, Shelar, Nitin, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Gawhane, Ashleshsa, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Madas, Sapna, Obaseki, Daniel, Erhabor, Gregory, Awopeju, Olayemi, Adewole, Olufemi, Horner, Andreas, Kaiser, Bernhard, McBurnie, Mary Ann, Buist, A. Sonia, Gnatiuc, Luisa, Bateman, Eric D., and Burney, Peter

Published
2019
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5. Obstructive Lung Disease and Exposure to Burning Biomass Fuel in the Indoor Environment

Author

Diette, Gregory B, Accinelli, Roberto A, Balmes, John R, Buist, A Sonia, Checkley, William, Garbe, Paul, Hansel, Nadia N, Kapil, Vikas, Gordon, Stephen, Lagat, David K, Yip, Fuyuen, Mortimer, Kevin, Perez-Padilla, Rogelio, Roth, Christa, Schwaninger, Julie M, Punturieri, Antonello, and Kiley, James P

Subjects
Health Effects of Indoor Air Pollution, Chronic Obstructive Pulmonary Disease, Asthma, Lung, Health Effects of Household Energy Combustion, Clinical Research, Pediatric Research Initiative, Climate-Related Exposures and Conditions, Aetiology, 2.2 Factors relating to the physical environment, Respiratory, Affordable and Clean Energy, Cardiorespiratory Medicine and Haematology
Abstract

It is estimated that up to half of the world's population burns biomass fuel (wood, crop residues, animal dung and coal) for indoor uses such as cooking, lighting and heating. As a result, a large proportion of women and children are exposed to high levels of household air pollution (HAP). The short and long term effects of these exposures on the respiratory health of this population are not clearly understood. On May 9-11, 2011 NIH held an international workshop on the "Health Burden of Indoor Air Pollution on Women and Children," in Arlington, VA. To gather information on the knowledge base on this topic and identify research gaps, ahead of the meeting we conducted a literature search using PubMed to identify publications that related to HAP, asthma, and chronic obstructive pulmonary disease (COPD). Abstracts were all analyzed and we report on those considered by the respiratory sub study group at the meeting to be most relevant to the field. Many of the studies published are symptom-based studies (as opposed to objective measures of lung function or clinical examination etc.) and measurement of HAP was not done. Many found some association between indoor exposures to biomass smoke as assessed by stove type (e.g., open fire vs. liquid propane gas) and respiratory symptoms such as wheeze and cough. Among the studies that examined objective measures (e.g. spirometry) as a health outcome, the data supporting an association between biomass smoke exposure and COPD in adult women are fairly robust, but the findings for asthma are mixed. If an association was observed between the exposures and lung function, most data seemed to demonstrate mild to moderate reductions in lung function, the pathophysiological mechanisms of which need to be investigated. In the end, the group identified a series of scientific gaps and opportunities for research that need to be addressed to better understand the respiratory effects of exposure to indoor burning of the different forms of biomass fuels.

Published
2012

6. Cohort Profile : Burden of Obstructive Lung Disease (BOLD) study

Author

Amaral, Andre F S, Potts, James, Knox-Brown, Ben, Bagkeris, Emmanouil, Harrabi, Imed, Cherkaski, Hamid Hacene, Agarwal, Dhiraj, Juvekar, Sanjay, Anand, Mahesh Padukudru, Gislason, Thorarinn, Nafees, Asaad Ahmed, Mortimer, Kevin, Janson, Christer, Loh, Li Cher, Paraguas, Stefanni Nonna, Denguezli, Meriam, Al Ghobain, Mohammed, Mannino, David, Njoroge, Martin W, Devereux, Graham, Seemungal, Terence, Barbara, Cristina, Kocabaş, Ali, Ahmed, Rana, Aquart-Stewart, Althea, Studnicka, Michael, Welte, Tobias, Tan, Wan C, van Zyl-Smit, Richard N, Koul, Parvaiz, Garcia-Larsen, Vanessa, Minelli, Cosetta, Buist, A Sonia, Burney, Peter, Amaral, Andre F S, Potts, James, Knox-Brown, Ben, Bagkeris, Emmanouil, Harrabi, Imed, Cherkaski, Hamid Hacene, Agarwal, Dhiraj, Juvekar, Sanjay, Anand, Mahesh Padukudru, Gislason, Thorarinn, Nafees, Asaad Ahmed, Mortimer, Kevin, Janson, Christer, Loh, Li Cher, Paraguas, Stefanni Nonna, Denguezli, Meriam, Al Ghobain, Mohammed, Mannino, David, Njoroge, Martin W, Devereux, Graham, Seemungal, Terence, Barbara, Cristina, Kocabaş, Ali, Ahmed, Rana, Aquart-Stewart, Althea, Studnicka, Michael, Welte, Tobias, Tan, Wan C, van Zyl-Smit, Richard N, Koul, Parvaiz, Garcia-Larsen, Vanessa, Minelli, Cosetta, Buist, A Sonia, and Burney, Peter

Published
2023
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8. Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study

Author

Ratanachina, Jate, primary, Amaral, Andre F.S., additional, De Matteis, Sara, additional, Lawin, Herve, additional, Mortimer, Kevin, additional, Obaseki, Daniel O., additional, Harrabi, Imed, additional, Denguezli, Meriam, additional, Wouters, Emiel F.M., additional, Janson, Christer, additional, Nielsen, Rune, additional, Gulsvik, Amund, additional, Cherkaski, Hamid Hacene, additional, Mejza, Filip, additional, Mahesh, Padukudru Anand, additional, Elsony, Asma, additional, Ahmed, Rana, additional, Tan, Wan, additional, Loh, Li Cher, additional, Rashid, Abdul, additional, Studnicka, Michael, additional, Nafees, Asaad A., additional, Seemungal, Terence, additional, Aquart-Stewart, Althea, additional, Al Ghobain, Mohammed, additional, Zheng, Jinping, additional, Juvekar, Sanjay, additional, Salvi, Sundeep, additional, Jogi, Rain, additional, Mannino, David, additional, Gislason, Thorarinn, additional, Buist, A. Sonia, additional, Cullinan, Paul, additional, and Burney, Peter, additional

Published
2022
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14. Challenges in the Implementation of Chronic Obstructive Pulmonary Disease Guidelines in Low- and Middle-Income Countries: An Official American Thoracic Society Workshop Report

Author

Hurst, John R., primary, Buist, A. Sonia, additional, Gaga, Mina, additional, Gianella, Gonzalo E., additional, Kirenga, Bruce, additional, Khoo, Ee Ming, additional, Mendes, Renata Gonçalves, additional, Mohan, Anant, additional, Mortimer, Kevin, additional, Rylance, Sarah, additional, Siddharthan, Trishul, additional, Singh, Sally J., additional, van Boven, Job F. M., additional, Williams, Siân, additional, Zhang, Jing, additional, and Checkley, William, additional

Published
2021
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15. Prevalence and Population-Attributable Risk for Chronic Airflow Obstruction in a Large Multinational Study

Author

Burney, Peter, primary, Patel, Jaymini, additional, Minelli, Cosetta, additional, Gnatiuc, Louisa, additional, Amaral, André F. S., additional, Kocabaş, Ali, additional, Cherkaski, Hamid Hacene, additional, Gulsvik, Amund, additional, Nielsen, Rune, additional, Bateman, Eric, additional, Jithoo, Anamika, additional, Mortimer, Kevin, additional, Sooronbaev, Talant M., additional, Lawin, Hervé, additional, Nejjari, Chakib, additional, Elbiaze, Mohammed, additional, El Rhazi, Karima, additional, Zheng, Jin-Ping, additional, Ran, Pixin, additional, Welte, Tobias, additional, Obaseki, Daniel, additional, Erhabor, Gregory, additional, Elsony, Asma, additional, Osman, Nada Bakri, additional, Ahmed, Rana, additional, Nizankowska-Mogilnicka, Ewa, additional, Mejza, Filip, additional, Mannino, David M., additional, Bárbara, Cristina, additional, Wouters, Emiel F. M., additional, Idolor, Luisito F., additional, Loh, Li-Cher, additional, Rashid, Abdul, additional, Juvekar, Sanjay, additional, Gislason, Thorarinn, additional, Al Ghobain, Mohamed, additional, Studnicka, Michael, additional, Harrabi, Imed, additional, Denguezli, Meriam, additional, Koul, Parvaiz A., additional, Jenkins, Christine, additional, Marks, Guy, additional, Jõgi, Rain, additional, Hafizi, Hasan, additional, Janson, Christer, additional, Tan, Wan C., additional, Aquart-Stewart, Althea, additional, Mbatchou, Bertrand, additional, Nafees, Asaad Ahmed, additional, Gunasekera, Kirthi, additional, Seemungal, Terry, additional, Anand, Mahesh Padukudru, additional, Enright, Paul, additional, Vollmer, William M., additional, Blangiardo, Marta, additional, Elfadaly, Fadlalla G., additional, Buist, A. Sonia, additional, Aliko, Anila, additional, Bardhi, Donika, additional, Tafa, Holta, additional, Thanasi, Natasha, additional, Mezini, Arian, additional, Teferici, Alma, additional, Todri, Dafina, additional, Nikolla, Jolanda, additional, Kazasi, Rezarta, additional, Bengrait, Amira, additional, Haddad, Tabarek, additional, Zgaoula, Ibtissem, additional, Ghit, Maamar, additional, Roubhia, Abdelhamid, additional, Boudra, Soumaya, additional, Atoui, Feryal, additional, Yakoubi, Randa, additional, Benali, Rachid, additional, Bencheikh, Abdelghani, additional, Ait-Khaled, Nadia, additional, Bird, Tessa, additional, Espinel, Paola, additional, Hardaker, Kate, additional, Toelle, Brett, additional, Dawes, Torkil, additional, Lamprecht, Bernd, additional, Schirhofer, Lea, additional, Islam, Akramul, additional, Ahmed, Syed Masud, additional, Islam, Shayla, additional, Islam, Qazi Shafayetul, additional, Chowdhury, Tridib Roy, additional, Chatterjee, Sukantha Kumar, additional, Mia, Dulal, additional, Das, Shyamal Chandra, additional, Rahman, Mizanur, additional, Islam, Nazrul, additional, Uddin, Shahaz, additional, Islam, Nurul, additional, Khatun, Luiza, additional, Parvin, Monira, additional, Khan, Abdul Awal, additional, Islam, Maidul, additional, Lawin, Herve, additional, Kpangon, Arsene, additional, Kpossou, Karl, additional, Agodokpessi, Gildas, additional, Ayelo, Paul, additional, Fayomi, Benjamin, additional, Ashu, Atongno Humphrey, additional, Wang, Wen, additional, Zhong, NanShan, additional, Liu, Shengming, additional, Lu, Jiachun, additional, Wang, Dali, additional, Zheng, Jin-ping, additional, Zhou, Yumin, additional, Laja, Hendrik, additional, Ulst, Katrin, additional, Zobel, Vappu, additional, Lill, Toomas-Julius, additional, Adegnika, Ayola Akim, additional, Bodemann, Isabelle, additional, Geldmacher, Henning, additional, Schweda-Linow, Alexandra, additional, Benedikdtsdottir, Bryndis, additional, Jörundsdottir, Kristin, additional, Gudmundsdottir, Lovisa, additional, Gudmundsdottir, Sigrun, additional, Gudmundsson, Gunnar, additional, Rao, Mahesh, additional, Malik, Sajjad, additional, Hakim, Nissar A., additional, Khan, Umar Hafiz, additional, Chowgule, Rohini, additional, Shetye, Vasant, additional, Raphael, Jonelle, additional, Almeda, Rosel, additional, Tawde, Mahesh, additional, Tadvi, Rafiq, additional, Katkar, Sunil, additional, Kadam, Milind, additional, Dhanawade, Rupesh, additional, Ghurup, Umesh, additional, Hirve, Siddhi, additional, Sambhudas, Somnath, additional, Chaidhary, Bharat, additional, Tambe, Meera, additional, Pingale, Savita, additional, Umap, Arati, additional, Umap, Archana, additional, Shelar, Nitin, additional, Devchakke, Sampada, additional, Chaudhary, Sharda, additional, Bondre, Suvarna, additional, Walke, Savita, additional, Gawhane, Ashleshsa, additional, Sapkal, Anil, additional, Argade, Rupali, additional, Gaikwad, Vijay, additional, Salvi, Sundeep, additional, Brashier, Bill, additional, Londhe, Jyoti, additional, Madas, Sapna, additional, Aikman, Akosua Francia, additional, Estebesova, Bermet M., additional, Akmatalieva, Meerim, additional, Usenbaeva, Saadat, additional, Kydyrova, Jypara, additional, Bostonova, Eliza, additional, Sheraliev, Ulan, additional, Marajapov, Nuridin, additional, Toktogulova, Nurgul, additional, Emilov, Berik, additional, Azilova, Toktogul, additional, Beishekeeva, Gulnara, additional, Dononbaeva, Nasyikat, additional, Tabyshova, Aijamal, additional, Nyapigoti, Wezzie, additional, Mwangoka, Ernest, additional, Kambwili, Mayamiko, additional, Chipeta, Martha, additional, Banda, Gloria, additional, Mkandawire, Suzgo, additional, Banda, Justice, additional, Sholehah, Siti, additional, Benjelloun, Mohamed C., additional, Elbiaze, Mohamed, additional, Wouters, E. F. M., additional, Wesseling, G. J., additional, Awopeju, Olayemi, additional, Adewole, Olufemi, additional, Endresen, Tina, additional, Svendsen, Lene, additional, Nafees, Asaad A., additional, de Guia, Teresita S., additional, Francisco, Norberto A., additional, Roa, Camilo C., additional, Ayuyao, Fernando G., additional, Tady, Cecil Z., additional, Tan, Daniel T., additional, Banal-Yang, Sylvia, additional, Balanag, Vincent M., additional, Reyes, Maria Teresita N., additional, Dantes, Renato. B., additional, Dantes, Renato B., additional, Amarillo, Lourdes, additional, Berratio, Lakan U., additional, Fernandez, Lenora C., additional, Garcia, Gerard S., additional, Naval, Sullian S., additional, Reyes, Thessa, additional, Sanchez, Ma. Flordeliza, additional, Simpao, Leander P., additional, Frey, Jakub, additional, Harat, Rafal, additional, Nastalek, Pawel, additional, Pajak, Andrzej, additional, Skucha, Wojciech, additional, Szczeklik, Andrzej, additional, Twardowska, Magda, additional, Rodrigues, Fátima, additional, Dias, Hermínia, additional, Cardoso, João, additional, Almeida, João, additional, Matos, Maria João, additional, Simão, Paula, additional, Santos, Moutinho, additional, Ferreira, Reis, additional, Al Ghobain, M., additional, Alorainy, H., additional, El-Hamad, E., additional, Al Hajjaj, M., additional, Hashi, A., additional, Dela, R., additional, Fanuncio, R., additional, Doloriel, E., additional, Marciano, I., additional, Safia, L., additional, Adams, Desiree, additional, Barnes, Edward, additional, Freeman, Jasper, additional, Hayes, Anton, additional, Hlengwa, Sipho, additional, Johannisen, Christine, additional, Koopman, Mariana, additional, Louw, Innocentia, additional, Ludick, Ina, additional, Olckers, Alta, additional, Ryck, Johanna, additional, Storbeck, Janita, additional, Wickremasinghe, Rajitha, additional, Elsadig, Hana A., additional, Osman, Nada Bakery, additional, Noory, Bandar Salah, additional, Mohamed, Monjda Awad, additional, Osman, Hasab Alrasoul Akasha Ahmed, additional, ed Elhassan, Namarig Moham, additional, Mu‘is El Zain, Abdel, additional, Mohamaden, Marwa Mohamed, additional, Khalifa, Suhaiba, additional, Elhadi, Mahmoud, additional, Hassan, Mohand, additional, Abdelmonam, Dalia, additional, Olafsdottir, Inga Sif, additional, Nisser, Katarina, additional, Spetz-Nyström, Ulrike, additional, Hägg, Gunilla, additional, Lund, Gun-Marie, additional, Seemungal, Terence, additional, Lutchmansingh, Fallon, additional, Conyette, Liane, additional, Denguezli, Myriam, additional, Tabka, Zouhair, additional, Daldoul, Hager, additional, Boukheroufa, Zaki, additional, Chouikha, Firas, additional, Khalifa, Wahbi Belhaj, additional, Hancioglu, Attila, additional, Hanta, Ismail, additional, Kuleci, Sedat, additional, Turkyilmaz, Ahmet Sinan, additional, Umut, Sema, additional, Unalan, Turgay, additional, Burney, Peter G. J., additional, Azar, Hadia, additional, Amor, Caron, additional, Potts, James, additional, Tumilty, Michael, additional, McLean, Fiona, additional, Dudhaiya, Risha, additional, McBurnie, Mary Ann, additional, Gillespie, Suzanne, additional, Sullivan, Sean, additional, Lee, Todd A., additional, Weiss, Kevin B., additional, Jensen, Robert L., additional, Crapo, Robert, additional, Cain, John, additional, Copeland, Rebecca, additional, Hazen, Dana, additional, and Methvin, Jennifer, additional

Published
2021
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16. Cumulative Occupational Exposures and Lung Function Decline in Two Large General Population Cohorts

Author

Lytras, Theodore, Beckmeyer-Borowko, Anna, Kogevinas, Manolis, Kromhout, Hans, Carsin, Anne-Elie, Antó, Josep Maria, Bentouhami, Hayat, Weyler, Joost, Heinrich, Joachim, Nowak, Dennis, Urrutia, Isabel, Martínez-Moratalla, Jesús, Gullón, José Antonio, Pereira Vega, Antonio, Raherison Semjen, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Villani, Simona, Gislason, Thorarinn, Svanes, Øistein, Holm, Mathias, Forsberg, Bertil, Norbäck, Dan, Mehta, Amar J, Keidel, Dirk, Vernez, David, Benke, Geza, Jõgi, Rain, Torén, Kjell, Sigsgaard, Torben, Schlünssen, Vivi, Olivieri, Mario, Blanc, Paul D, Watkins, John, Bono, Roberto, Squillacioti, Giulia, Buist, A Sonia, Vermeulen, Roel, Jarvis, Deborah, Probst-Hensch, Nicole, Zock, Jan-Paul, Lytras, Theodore, Beckmeyer-Borowko, Anna, Kogevinas, Manolis, Kromhout, Hans, Carsin, Anne-Elie, Antó, Josep Maria, Bentouhami, Hayat, Weyler, Joost, Heinrich, Joachim, Nowak, Dennis, Urrutia, Isabel, Martínez-Moratalla, Jesús, Gullón, José Antonio, Pereira Vega, Antonio, Raherison Semjen, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Villani, Simona, Gislason, Thorarinn, Svanes, Øistein, Holm, Mathias, Forsberg, Bertil, Norbäck, Dan, Mehta, Amar J, Keidel, Dirk, Vernez, David, Benke, Geza, Jõgi, Rain, Torén, Kjell, Sigsgaard, Torben, Schlünssen, Vivi, Olivieri, Mario, Blanc, Paul D, Watkins, John, Bono, Roberto, Squillacioti, Giulia, Buist, A Sonia, Vermeulen, Roel, Jarvis, Deborah, Probst-Hensch, Nicole, and Zock, Jan-Paul

Abstract

RATIONALE: Few longitudinal studies have assessed the relationship between occupational exposures and lung function decline in the general population, with sufficiently long follow-up.OBJECTIVES: Our objective was to examine this potential association in two large cohorts (ECRHS and SAPALDIA).METHODS: General population samples aged 18 to 62 were randomly selected in 1991-1993, and followed up approximately 10 and 20 years later. Spirometry (without bronchodilation) was performed at each visit. Coded complete job histories during follow-up visits were linked to a Job-Exposure Matrix, generating cumulative exposure estimates for 12 occupational exposures. FEV1 and FVC were jointly modelled in linear mixed-effects models, fitted in a Bayesian framework, taking into account age and smoking.RESULTS: A total of 40,024 lung function measurements from 17,833 study participants were analyzed. We found accelerated declines in FEV1 and the FEV1/FVC ratio for exposure to biological dust, mineral dust and metals (FEV1 -15.1ml, -14.4ml and -18.7ml respectively, and FEV1/FVC -0.52%, -0.43% and -0.36% respectively, per 25 intensity-years of exposure). These declines were comparable in magnitude to those associated with long-term smoking. No effect modification by sex or smoking status was identified. Findings were similar between the ECRHS and SAPALDIA cohorts.CONCLUSIONS: Our results greatly strengthen the evidence base implicating occupation, independent of smoking, as a risk factor for lung function decline. This highlights the need to prevent or control these exposures in the workplace.

Published
2021

17. Prevalence and Population-Attributable Risk for Chronic Airflow Obstruction in a Large Multinational Study

Author

Burney, Peter, Patel, Jaymini, Minelli, Cosetta, Gnatiuc, Louisa, Amaral, André F. S., Kocabaş, Ali, Cherkaski, Hamid Hacene, Gulsvik, Amund, Nielsen, Rune, Bateman, Eric, Jithoo, Anamika, Mortimer, Kevin, Sooronbaev, Talant M., Lawin, Hervé, Nejjari, Chakib, Elbiaze, Mohammed, El Rhazi, Karima, Zheng, Jin-Ping, Ran, Pixin, Welte, Tobias, Obaseki, Daniel, Erhabor, Gregory, Elsony, Asma, Osman, Nada Bakri, Ahmed, Rana, Nizankowska-Mogilnicka, Ewa, Mejza, Filip, Mannino, David M., Bárbara, Cristina, Wouters, Emiel F. M., Idolor, Luisito F., Loh, Li-Cher, Rashid, Abdul, Juvekar, Sanjay, Gislason, Thorarinn, Al Ghobain, Mohamed, Studnicka, Michael, Harrabi, Imed, Denguezli, Meriam, Koul, Parvaiz A., Jenkins, Christine, Marks, Guy, Jõgi, Rain, Hafizi, Hasan, Janson, Christer, Tan, Wan C., Aquart-Stewart, Althea, Mbatchou, Bertrand, Nafees, Asaad, Gunasekera, Kirthi, Seemungal, Terry, Padukudru Anand, Mahesh, Enright, Paul, Vollmer, William M., Blangiardo, Marta, Elfadaly, Fadlalla G., Buist, A. Sonia, Burney, Peter, Patel, Jaymini, Minelli, Cosetta, Gnatiuc, Louisa, Amaral, André F. S., Kocabaş, Ali, Cherkaski, Hamid Hacene, Gulsvik, Amund, Nielsen, Rune, Bateman, Eric, Jithoo, Anamika, Mortimer, Kevin, Sooronbaev, Talant M., Lawin, Hervé, Nejjari, Chakib, Elbiaze, Mohammed, El Rhazi, Karima, Zheng, Jin-Ping, Ran, Pixin, Welte, Tobias, Obaseki, Daniel, Erhabor, Gregory, Elsony, Asma, Osman, Nada Bakri, Ahmed, Rana, Nizankowska-Mogilnicka, Ewa, Mejza, Filip, Mannino, David M., Bárbara, Cristina, Wouters, Emiel F. M., Idolor, Luisito F., Loh, Li-Cher, Rashid, Abdul, Juvekar, Sanjay, Gislason, Thorarinn, Al Ghobain, Mohamed, Studnicka, Michael, Harrabi, Imed, Denguezli, Meriam, Koul, Parvaiz A., Jenkins, Christine, Marks, Guy, Jõgi, Rain, Hafizi, Hasan, Janson, Christer, Tan, Wan C., Aquart-Stewart, Althea, Mbatchou, Bertrand, Nafees, Asaad, Gunasekera, Kirthi, Seemungal, Terry, Padukudru Anand, Mahesh, Enright, Paul, Vollmer, William M., Blangiardo, Marta, Elfadaly, Fadlalla G., and Buist, A. Sonia

Abstract

Rationale: The Global Burden of Disease program identified smoking and ambient and household air pollution as the main drivers of death and disability from chronic obstructive pulmonary disease (COPD). Objectives: To estimate the attributable risk of chronic airflow obstruction (CAO), a quantifiable characteristic of COPD, due to several risk factors. Methods: The Burden of Obstructive Lung Disease study is a cross-sectional study of adults, aged ≥40, in a globally distributed sample of 41 urban and rural sites. Based on data from 28,459 participants, we estimated the prevalence of CAO, defined as a postbronchodilator FEV1-to-FVC ratio less than the lower limit of normal, and the relative risks associated with different risk factors. Local relative risks were estimated using a Bayesian hierarchical model borrowing information from across sites. From these relative risks and the prevalence of risk factors, we estimated local population attributable risks. Measurements and Main Results: The mean prevalence of CAO was 11.2% in men and 8.6% in women. The mean population attributable risk for smoking was 5.1% in men and 2.2% in women. The next most influential risk factors were poor education levels, working in a dusty job for ≥10 years, low body mass index, and a history of tuberculosis. The risk of CAO attributable to the different risk factors varied across sites. Conclusions: Although smoking remains the most important risk factor for CAO, in some areas, poor education, low body mass index, and passive smoking are of greater importance. Dusty occupations and tuberculosis are important risk factors at some sites.

Published
2021
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18. Chronic airflow obstruction and ambient particulate air pollution

Author

Amaral, Andre F. S., Burney, Peter G. J., Patel, Jaymini, Minelli, Cosetta, Mejza, Filip, Mannino, David M., Seemungal, Terence A. R., Mahesh, Padukudru Anand, Lo, Li Cher, Janson, Christer, Juvekar, Sanjay, Denguezli, Meriam, Harrabi, Imed, Wouters, Emiel F. M., Cherkaski, Hamid, Mortimer, Kevin, Jogi, Rain, Bateman, Eric D., Fuertes, Elaine, Al Ghobain, Mohammed, Tan, Wan, Obaseki, Daniel O., El Sony, Asma, Studnicka, Michael, Aquart-Stewart, Althea, Koul, Parvaiz, Lawin, Herve, Nafees, Asaad Ahmed, Awopeju, Olayemi, Erhabor, Gregory E., Gislason, Thorarinn, Welte, Tobias, Gulsvik, Amund, Nielsen, Rune, Gnatiuc, Louisa, Kocabas, Ali, Marks, Guy B., Sooronbaev, Talant, Mbatchou Ngahane, Bertrand Hugo, Barbara, Cristina, Buist, A. Sonia, Amaral, Andre F. S., Burney, Peter G. J., Patel, Jaymini, Minelli, Cosetta, Mejza, Filip, Mannino, David M., Seemungal, Terence A. R., Mahesh, Padukudru Anand, Lo, Li Cher, Janson, Christer, Juvekar, Sanjay, Denguezli, Meriam, Harrabi, Imed, Wouters, Emiel F. M., Cherkaski, Hamid, Mortimer, Kevin, Jogi, Rain, Bateman, Eric D., Fuertes, Elaine, Al Ghobain, Mohammed, Tan, Wan, Obaseki, Daniel O., El Sony, Asma, Studnicka, Michael, Aquart-Stewart, Althea, Koul, Parvaiz, Lawin, Herve, Nafees, Asaad Ahmed, Awopeju, Olayemi, Erhabor, Gregory E., Gislason, Thorarinn, Welte, Tobias, Gulsvik, Amund, Nielsen, Rune, Gnatiuc, Louisa, Kocabas, Ali, Marks, Guy B., Sooronbaev, Talant, Mbatchou Ngahane, Bertrand Hugo, Barbara, Cristina, and Buist, A. Sonia

Abstract

Smoking is the most well-established cause of chronic airflow obstruction (CAO) but particulate air pollution and poverty have also been implicated. We regressed sex-specific prevalence of CAO from 41 Burden of Obstructive Lung Disease study sites against smoking prevalence from the same study, the gross national income per capita and the local annual mean level of ambient particulate matter (PM2.5) using negative binomial regression. The prevalence of CAO was not independently associated with PM2.5 but was strongly associated with smoking and was also associated with poverty. Strengthening tobacco control and improved understanding of the link between CAO and poverty should be prioritised.

Published
2021
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19. Cumulative Occupational Exposures and Lung Function Decline in Two Large General Population Cohorts

Author

IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Dep IRAS, Lytras, Theodore, Beckmeyer-Borowko, Anna, Kogevinas, Manolis, Kromhout, Hans, Carsin, Anne-Elie, Antó, Josep Maria, Bentouhami, Hayat, Weyler, Joost, Heinrich, Joachim, Nowak, Dennis, Urrutia, Isabel, Martínez-Moratalla, Jesús, Gullón, José Antonio, Pereira Vega, Antonio, Raherison Semjen, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Villani, Simona, Gislason, Thorarinn, Svanes, Øistein, Holm, Mathias, Forsberg, Bertil, Norbäck, Dan, Mehta, Amar J, Keidel, Dirk, Vernez, David, Benke, Geza, Jõgi, Rain, Torén, Kjell, Sigsgaard, Torben, Schlünssen, Vivi, Olivieri, Mario, Blanc, Paul D, Watkins, John, Bono, Roberto, Squillacioti, Giulia, Buist, A Sonia, Vermeulen, Roel, Jarvis, Deborah, Probst-Hensch, Nicole, Zock, Jan-Paul, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Dep IRAS, Lytras, Theodore, Beckmeyer-Borowko, Anna, Kogevinas, Manolis, Kromhout, Hans, Carsin, Anne-Elie, Antó, Josep Maria, Bentouhami, Hayat, Weyler, Joost, Heinrich, Joachim, Nowak, Dennis, Urrutia, Isabel, Martínez-Moratalla, Jesús, Gullón, José Antonio, Pereira Vega, Antonio, Raherison Semjen, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Villani, Simona, Gislason, Thorarinn, Svanes, Øistein, Holm, Mathias, Forsberg, Bertil, Norbäck, Dan, Mehta, Amar J, Keidel, Dirk, Vernez, David, Benke, Geza, Jõgi, Rain, Torén, Kjell, Sigsgaard, Torben, Schlünssen, Vivi, Olivieri, Mario, Blanc, Paul D, Watkins, John, Bono, Roberto, Squillacioti, Giulia, Buist, A Sonia, Vermeulen, Roel, Jarvis, Deborah, Probst-Hensch, Nicole, and Zock, Jan-Paul

Published
2021

20. COPD: Should Diagnosis Match Physiology?

Author

Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jingping, Zhou, Yumin, Kocabaş, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Studnicka, Michael, Dawes, Torkil, Lamprecht, Bernd, Sator, Lea, Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jörundsdottir, Kristin, Gudmundsdottir, Lovisa, Gudmundsdottir, Sigrun, Gundmundsson, Gunnar, Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Pajak, Andrzej, Skucha, Wojciech, Szczeklik, Andrzej, Twardowska, Magda, Welte, Tobias, Bodemann, Isabelle, Geldmacher, Henning, Schweda-Linow, Alexandra, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Tan, Wan C., Wang, Wen, Mannino, David M., Cain, John, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Dantes, Renato B., Amarillo, Lourdes, Berratio, Lakan U., Fernandez, Lenora C., Francisco, Norberto A., Garcia, Gerard S., de Guia, Teresita S., Idolor, Luisito F., Naval, Sullian S., Reyes, Thessa, Roa, Camilo C., Jr, Sanchez, Ma. Flordeliza, Simpao, Leander P., Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Burney, Peter G.J., Amor, Caron, Potts, James, Tumilty, Michael, McLean, Fiona, Wouters, E.F.M., Wesseling, G.J., Bárbara, Cristina, Rodrigues, Fátima, Dias, Hermínia, Cardoso, João, Almeida, João, Matos, Maria João, Simão, Paula, Santos, Moutinho, Ferreira, Reis, Janson, Christer, Olafsdottir, Inga Sif, Nisser, Katarina, Spetz-Nyström, Ulrike, Hägg, Gunilla, Lund, Gun-Marie, Jõgi, Rain, Laja, Hendrik, Ulst, Katrin, Zobel, Vappu, Lill, Toomas-Julius, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Raphael, Jonelle, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Katkar, Sunil, Kadam, Milind, Dhanawade, Rupesh, Ghurup, Umesh, Harrabi, Imed, Denguezli, Myriam, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Roa, Camilo C., Ayuyao, Fernando G., Tady, Cecil Z., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Jr, Reyes, Maria Teresita N., Dantes, Renato. B., Juvekar, Sanjay, Hirve, Siddhi, Sambhudas, Somnath, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Arati, Umap, Archana, Shelar, Nitin, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Gawhane, Ashleshsa, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Madas, Sapna, Obaseki, Daniel, Erhabor, Gregory, Awopeju, Olayemi, Adewole, Olufemi, Horner, Andreas, and Buist, A. Sonia

Published
2020
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21. Bronchodilator reversibility in asthma and COPD: Findings from three large population studies

Author

Janson, Christer, Malinovschi, Andrei, Amaral, Andre, Accordini, Simone, Bousquet, Jean, Buist, A Sonia, Canonica, Giorgio Walter, Dahlén, Barbro, Garcia-Aymerich, Judith, Gnatiuc, Louisa, Kowalski, Marek, Patel, Jaymini, Tan, Wan, Torén, Kjell, Zuberbier, Torsten, Burney, Peter, Jarvis, Deborah, Amaral, Andre F.S., Buist, A. Sonia, Commission of the European Communities, Wellcome Trust, Medical Research Council (MRC), Kaiser Foundation Hospitals,Center for Health Research, Sociedade Portuguesa de Pneumologia, Tartu University Hospital, Ciro Horn, Department of Medical Sciences, Respiratory Medicine & Allergology, Uppsala University, Population Health and Occupational Disease [Londres, Royaume-Uni], National Heart and Lung Institute [Londres, Royaume-Uni] (NHLI), Imperial College London-Imperial College London, Department of Diagnostics and Public Health [Verona] (UNIVR | DDSP), University of Verona (UNIVR), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Humanitas Clinical and Research Center [Rozzano, Milan, Italy], University of British Columbia (UBC), Sahlgrenska Academy at University of Gothenburg, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université Montpellier 1 (UM1)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), and Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)

Subjects
Male, Internationality, Respiratory System, ECRHS, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, RESPONSIVENESS, Pulmonary Disease, Chronic Obstructive, FEV1, 0302 clinical medicine, Forced Expiratory Volume, Bronchodilator, 030212 general & internal medicine, 11 Medical and Health Sciences, Aged, 80 and over, COPD, education.field_of_study, medicine.diagnostic_test, Middle Aged, respiratory system, Bronchodilator Agents, 3. Good health, TIME, LUNG-FUNCTION, Female, medicine.symptom, Life Sciences & Biomedicine, Adult, Pulmonary and Respiratory Medicine, Spirometry, medicine.medical_specialty, Adolescent, medicine.drug_class, prevalence, Population, GA2LEN, Young Adult, 03 medical and health sciences, FEV1/FVC ratio, Internal medicine, Wheeze, Administration, Inhalation, NITRIC-OXIDE LEVELS, medicine, Humans, Albuterol, VALIDITY, education, Aged, Asthma, Science & Technology, business.industry, asthma, BOLD, bronchodilator reversibility, COPD, ECRHS, GA2LEN, prevalence, asthma, medicine.disease, FVC, respiratory tract diseases, bronchodilator reversibility, Logistic Models, 030228 respiratory system, Multivariate Analysis, Exhaled nitric oxide, OBSTRUCTION, business, BOLD
Abstract

Bronchodilator response (BDR) testing is used as a diagnostic method in obstructive airway diseases. The aim of this investigation was to compare different methods for measuring BDR in participants with asthma and chronic obstructive pulmonary disease (COPD) and to study to the extent to which BDR was related to symptom burden and phenotypic characteristics.Forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) were measured before and 15 min after 200 μg of salbutamol in 35 628 subjects aged ≥16 years from three large international population studies. The subjects were categorised in three groups: current asthma (n=2833), COPD (n=1146) and no airway disease (n=31 649). Three definitions for flow-related reversibility (increase in FEV1) and three for volume-related reversibility (increase in FVC) were used.The prevalence of bronchodilator reversibility expressed as increase FEV1 ≥12% and 200 mL was 17.3% and 18.4% in participants with asthma and COPD, respectively, while the corresponding prevalence was 5.1% in those with no airway disease. In asthma, bronchodilator reversibility was associated with wheeze (OR 1.36, 95% CI 1.04–1.79), atopy (OR 1.36, 95% CI 1.04–1.79) and higher exhaled nitric oxide fraction, while in COPD neither flow- nor volume-related bronchodilator reversibility was associated with symptom burden, exacerbations or health status after adjusting for pre-bronchodilator FEV1.Bronchodilator reversibility was at least as common in participants with COPD as those with asthma. This indicates that measures of reversibility are of limited value for distinguishing asthma from COPD in population studies. However, in asthma, bronchodilator reversibility may be a phenotypic marker.

Published
2019

22. Chronic airflow obstruction and ambient particulate air pollution

Author

Amaral, Andre F S, primary, Burney, Peter G J, additional, Patel, Jaymini, additional, Minelli, Cosetta, additional, Mejza, Filip, additional, Mannino, David M, additional, Seemungal, Terence A R, additional, Mahesh, Padukudru Anand, additional, Lo, Li Cher, additional, Janson, Christer, additional, Juvekar, Sanjay, additional, Denguezli, Meriam, additional, Harrabi, Imed, additional, Wouters, Emiel F M, additional, Cherkaski, Hamid, additional, Mortimer, Kevin, additional, Jogi, Rain, additional, Bateman, Eric D, additional, Fuertes, Elaine, additional, Al Ghobain, Mohammed, additional, Tan, Wan, additional, Obaseki, Daniel O, additional, El Sony, Asma, additional, Studnicka, Michael, additional, Aquart-Stewart, Althea, additional, Koul, Parvaiz, additional, Lawin, Herve, additional, Nafees, Asaad Ahmed, additional, Awopeju, Olayemi, additional, Erhabor, Gregory E, additional, Gislason, Thorarinn, additional, Welte, Tobias, additional, Gulsvik, Amund, additional, Nielsen, Rune, additional, Gnatiuc, Louisa, additional, Kocabas, Ali, additional, Marks, Guy B, additional, Sooronbaev, Talant, additional, Mbatchou Ngahane, Bertrand Hugo, additional, Barbara, Cristina, additional, and Buist, A Sonia, additional

Published
2021
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23. Increase in Airway Obstruction between 1993 and 2012 in Switzerland. An Observational Study

Author

West, Erin A, Strassmann, Alexandra, Wang, Craig, Turk, Alexander, de Hoogh, Kees, Röösli, Martin, Bopp, Matthias, Buist, A Sonia, Dressel, Holger, Puhan, Milo A, University of Zurich, and Puhan, Milo A

Subjects
Pulmonary and Respiratory Medicine, 2740 Pulmonary and Respiratory Medicine, 610 Medicine & health, 10060 Epidemiology, Biostatistics and Prevention Institute (EBPI)
Published
2020

24. COPD: should diagnosis match physiology?

Author

Studnicka, Michael, Horner, Andreas, Sator, Lea, Buist, A. Sonia, Lamprecht, Bernd, Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jingping, Zhou, Yumin, Kocabaş, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Dawes, Torkil, Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jörundsdottir, Kristin, Gudmundsdottir, Lovisa, Gudmundsdottir, Sigrun, Gundmundsson, Gunnar, Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Pajak, Andrzej, Skucha, Wojciech, Szczeklik, Andrzej, Twardowska, Magda, Welte, Tobias, Bodemann, Isabelle, Geldmacher, Henning, Schweda-Linow, Alexandra, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Tan, Wan C., Wang, Wen, Mannino, David M., Cain, John, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Dantes, Renato B., Amarillo, Lourdes, Berratio, Lakan U., Fernandez, Lenora C., Francisco, Norberto A., Garcia, Gerard S., de Guia, Teresita S., Idolor, Luisito F., Naval, Sullian S., Reyes, Thessa, Roa, Camilo C., Sanchez, Ma. Flordeliza, Simpao, Leander P., Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Burney, Peter G.J., Amor, Caron, Potts, James, Tumilty, Michael, McLean, Fiona, Wouters, E.F.M., Wesseling, G.J., Bárbara, Cristina, Rodrigues, Fátima, Dias, Hermínia, Cardoso, João, Almeida, João, Matos, Maria João, Simão, Paula, Santos, Moutinho, Ferreira, Reis, Janson, Christer, Olafsdottir, Inga Sif, Nisser, Katarina, Spetz-Nyström, Ulrike, Hägg, Gunilla, Lund, Gun-Marie, Jõgi, Rain, Laja, Hendrik, Ulst, Katrin, Zobel, Vappu, Lill, Toomas-Julius, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Raphael, Jonelle, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Katkar, Sunil, Kadam, Milind, Dhanawade, Rupesh, Ghurup, Umesh, Harrabi, Imed, Denguezli, Myriam, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Ayuyao, Fernando G., Tady, Cecil Z., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Reyes, Maria Teresita N., Dantes, Renato. B., Juvekar, Sanjay, Hirve, Siddhi, Sambhudas, Somnath, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Arati, Umap, Archana, Shelar, Nitin, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Gawhane, Ashleshsa, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Madas, Sapna, Obaseki, Daniel, Erhabor, Gregory, Awopeju, Olayemi, and Adewole, Olufemi

Subjects
Spirometry, Chronic obstructive pulmonary disease, Humans
Abstract

Submitted by Maria da Luz Antunes (mluz.antunes@estesl.ipl.pt) on 2020-12-08T16:58:31Z No. of bitstreams: 1 COPD_should diagnosis match physiology.pdf: 83490 bytes, checksum: bbbfcb5fa3e4d33e5d07d47e299641c6 (MD5) Made available in DSpace on 2020-12-08T16:58:31Z (GMT). No. of bitstreams: 1 COPD_should diagnosis match physiology.pdf: 83490 bytes, checksum: bbbfcb5fa3e4d33e5d07d47e299641c6 (MD5) Previous issue date: 2020-02 info:eu-repo/semantics/publishedVersion

Published
2020

27. Increase in Airway Obstruction between 1993 and 2012 in Switzerland. An Observational Study

Author

West, Erin A; https://orcid.org/0000-0001-7339-3819, Strassmann, Alexandra, Wang, Craig, Turk, Alexander, de Hoogh, Kees, Röösli, Martin, Bopp, Matthias, Buist, A Sonia, Dressel, Holger, Puhan, Milo A, West, Erin A; https://orcid.org/0000-0001-7339-3819, Strassmann, Alexandra, Wang, Craig, Turk, Alexander, de Hoogh, Kees, Röösli, Martin, Bopp, Matthias, Buist, A Sonia, Dressel, Holger, and Puhan, Milo A

Abstract

Rationale: Most studies determining the prevalence of airway obstruction are limited to short time periods.Objectives: Because temporal trends of obstruction in populations are largely unknown, we determined the prevalence of airway obstruction over 20 years in yearly general population samples in Switzerland between 1993 and 2012.Methods: We analyzed data of 85,789 participants aged 35 years and older who provided spirometric measurements as part of the LuftiBus lung function campaign. We linked data from the 2003-2012 period to the Swiss National Cohort to adjust for annual population differences. Spirometry was performed without bronchodilation, according to American Thoracic Society guidelines. We used Global Lung Initiative (GLI) and Hankinson reference equations to identify obstruction.Results: Obstruction prevalence increased between 1993 and 2012 from 6.1% (95% confidence interval [CI], 5.5 to 6.7) to 15.6% (95% CI, 13.8 to 17.3) based on GLI estimates and from 5.3% (95% CI, 4.7 to 5.9) to 15.4% (95% CI, 13.6 to 17.1) based on Hankinson estimates. When adjusted for participant demographics, air pollutant and occupational exposures, altitude, and season, the prevalence ratios of obstruction were 1.54 (95% CI, 1.22 to 1.93) and 1.65 (95% CI, 1.33 to 2.04) for GLI- and Hankinson-defined airway obstruction, respectively, for 2012 compared with 2003.Conclusions: Though prebronchodilator measurements likely overestimate the prevalence of airway obstruction in absolute terms compared with post-bronchodilator measurements, we found an increase in airway obstruction prevalence. Even with adjustment for several well-known risk factors for obstruction to make the populations across the years more comparable, we still saw a statistically significant increase in prevalence over this time period.

Published
2020

29. Cumulative Occupational Exposures and Lung-Function Decline in Two Large General-Population Cohorts

Author

Lytras, Theodore, primary, Beckmeyer-Borowko, Anna, additional, Kogevinas, Manolis, additional, Kromhout, Hans, additional, Carsin, Anne-Elie, additional, Antó, Josep Maria, additional, Bentouhami, Hayat, additional, Weyler, Joost, additional, Heinrich, Joachim, additional, Nowak, Dennis, additional, Urrutia, Isabel, additional, Martínez-Moratalla, Jesús, additional, Gullón, José Antonio, additional, Pereira Vega, Antonio, additional, Raherison Semjen, Chantal, additional, Pin, Isabelle, additional, Demoly, Pascal, additional, Leynaert, Bénédicte, additional, Villani, Simona, additional, Gislason, Thorarinn, additional, Svanes, Øistein, additional, Holm, Mathias, additional, Forsberg, Bertil, additional, Norbäck, Dan, additional, Mehta, Amar J., additional, Keidel, Dirk, additional, Vernez, David, additional, Benke, Geza, additional, Jõgi, Rain, additional, Torén, Kjell, additional, Sigsgaard, Torben, additional, Schlünssen, Vivi, additional, Olivieri, Mario, additional, Blanc, Paul D., additional, Watkins, John, additional, Bono, Roberto, additional, Squillacioti, Giulia, additional, Buist, A. Sonia, additional, Vermeulen, Roel, additional, Jarvis, Deborah, additional, Probst-Hensch, Nicole, additional, and Zock, Jan-Paul, additional

Published
2021
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36. COPD

Author

Studnicka, Michael, primary, Horner, Andreas, additional, Sator, Lea, additional, Buist, A. Sonia, additional, Lamprecht, Bernd, additional, Zhong, NanShan, additional, Liu, Shengming, additional, Lu, Jiachun, additional, Ran, Pixin, additional, Wang, Dali, additional, Zheng, Jingping, additional, Zhou, Yumin, additional, Kocabaş, Ali, additional, Hancioglu, Attila, additional, Hanta, Ismail, additional, Kuleci, Sedat, additional, Turkyilmaz, Ahmet Sinan, additional, Umut, Sema, additional, Unalan, Turgay, additional, Studnicka, Michael, additional, Dawes, Torkil, additional, Bateman, Eric, additional, Jithoo, Anamika, additional, Adams, Desiree, additional, Barnes, Edward, additional, Freeman, Jasper, additional, Hayes, Anton, additional, Hlengwa, Sipho, additional, Johannisen, Christine, additional, Koopman, Mariana, additional, Louw, Innocentia, additional, Ludick, Ina, additional, Olckers, Alta, additional, Ryck, Johanna, additional, Storbeck, Janita, additional, Gislason, Thorarinn, additional, Benedikdtsdottir, Bryndis, additional, Jörundsdottir, Kristin, additional, Gudmundsdottir, Lovisa, additional, Gudmundsdottir, Sigrun, additional, Gundmundsson, Gunnar, additional, Nizankowska-Mogilnicka, Ewa, additional, Frey, Jakub, additional, Harat, Rafal, additional, Mejza, Filip, additional, Nastalek, Pawel, additional, Pajak, Andrzej, additional, Skucha, Wojciech, additional, Szczeklik, Andrzej, additional, Twardowska, Magda, additional, Welte, Tobias, additional, Bodemann, Isabelle, additional, Geldmacher, Henning, additional, Schweda-Linow, Alexandra, additional, Gulsvik, Amund, additional, Endresen, Tina, additional, Svendsen, Lene, additional, Tan, Wan C., additional, Wang, Wen, additional, Mannino, David M., additional, Cain, John, additional, Copeland, Rebecca, additional, Hazen, Dana, additional, Methvin, Jennifer, additional, Dantes, Renato B., additional, Amarillo, Lourdes, additional, Berratio, Lakan U., additional, Fernandez, Lenora C., additional, Francisco, Norberto A., additional, Garcia, Gerard S., additional, de Guia, Teresita S., additional, Idolor, Luisito F., additional, Naval, Sullian S., additional, Reyes, Thessa, additional, Roa, Camilo C., additional, Sanchez, Ma. Flordeliza, additional, Simpao, Leander P., additional, Jenkins, Christine, additional, Marks, Guy, additional, Bird, Tessa, additional, Espinel, Paola, additional, Hardaker, Kate, additional, Toelle, Brett, additional, Burney, Peter G.J., additional, Amor, Caron, additional, Potts, James, additional, Tumilty, Michael, additional, McLean, Fiona, additional, Wouters, E.F.M., additional, Wesseling, G.J., additional, Bárbara, Cristina, additional, Rodrigues, Fátima, additional, Dias, Hermínia, additional, Cardoso, João, additional, Almeida, João, additional, Matos, Maria João, additional, Simão, Paula, additional, Santos, Moutinho, additional, Ferreira, Reis, additional, Janson, Christer, additional, Olafsdottir, Inga Sif, additional, Nisser, Katarina, additional, Spetz-Nyström, Ulrike, additional, Hägg, Gunilla, additional, Lund, Gun-Marie, additional, Jõgi, Rain, additional, Laja, Hendrik, additional, Ulst, Katrin, additional, Zobel, Vappu, additional, Lill, Toomas-Julius, additional, Koul, Parvaiz A., additional, Malik, Sajjad, additional, Hakim, Nissar A., additional, Khan, Umar Hafiz, additional, Chowgule, Rohini, additional, Shetye, Vasant, additional, Raphael, Jonelle, additional, Almeda, Rosel, additional, Tawde, Mahesh, additional, Tadvi, Rafiq, additional, Katkar, Sunil, additional, Kadam, Milind, additional, Dhanawade, Rupesh, additional, Ghurup, Umesh, additional, Harrabi, Imed, additional, Denguezli, Myriam, additional, Tabka, Zouhair, additional, Daldoul, Hager, additional, Boukheroufa, Zaki, additional, Chouikha, Firas, additional, Khalifa, Wahbi Belhaj, additional, Ayuyao, Fernando G., additional, Tady, Cecil Z., additional, Tan, Daniel T., additional, Banal-Yang, Sylvia, additional, Balanag, Vincent M., additional, Reyes, Maria Teresita N., additional, Dantes, Renato. B., additional, Juvekar, Sanjay, additional, Hirve, Siddhi, additional, Sambhudas, Somnath, additional, Chaidhary, Bharat, additional, Tambe, Meera, additional, Pingale, Savita, additional, Umap, Arati, additional, Umap, Archana, additional, Shelar, Nitin, additional, Devchakke, Sampada, additional, Chaudhary, Sharda, additional, Bondre, Suvarna, additional, Walke, Savita, additional, Gawhane, Ashleshsa, additional, Sapkal, Anil, additional, Argade, Rupali, additional, Gaikwad, Vijay, additional, Salvi, Sundeep, additional, Brashier, Bill, additional, Londhe, Jyoti, additional, Madas, Sapna, additional, Obaseki, Daniel, additional, Erhabor, Gregory, additional, Awopeju, Olayemi, additional, and Adewole, Olufemi, additional

Published
2020
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37. Testing bronchodilator responsiveness

Author

Janson, Christer, primary, Malinovschi, Andrei, additional, Amaral, Andre F.S., additional, Accordini, Simone, additional, Bousquet, Jean, additional, Buist, A. Sonia, additional, Garcia-Aymerich, Judith, additional, Gnatiuc, Louisa, additional, Tan, Wan, additional, Torén, Kjell, additional, Zuberbier, Torsten, additional, and Burney, Peter, additional

Published
2019
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39. Overdiagnosis of COPD in Subjects With Unobstructed Spirometry A BOLD Analysis

Author

Sator, Lea, Horner, Andreas, Studnicka, Michael, Lamprecht, Bernd, Kaiser, Bernhard, McBurnie, Mary Ann, Buist, A. Sonia, Gnatiuc, Luisa, Mannino, David M., Janson, Christer, Bateman, Eric D., Burney, Peter, Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jingping, Zhou, Yumin, Kocabas, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Dawes, Torkil, Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jorundsdottir, Kristin, Gudmundsdottir, Lovisa, Gudmundsdottir, Sigrun, Gundmundsson, Gunnar, Nizankowska-Mogilnicka, Ewa, Wouters, E. F. M., Wesseling, G. J., MUMC+: MA Longziekten (3), RS: NUTRIM - R3 - Respiratory & Age-related Health, Pulmonologie, MUMC+: MA Med Staf Spec Longziekten (9), and RS: CAPHRI - R5 - Optimising Patient Care

Subjects
COUNTRIES, SYMPTOMS, overtreatment, false positive diagnosis, ACCURACY, overdiagnosis, DIAGNOSIS, OBSTRUCTIVE PULMONARY-DISEASE, PREVALENCE, UNDERDIAGNOSIS, DEFINITIONS, SEVERITY, COPD, QUALITY, misdiagnosis
Abstract

BACKGROUND: There are several reports on underdiagnosis of COPD, while little is known about COPD overdiagnosis and overtreatment. We describe the overdiagnosis and the prevalence of spirometrically defined false positive COPD, as well as their relationship with overtreatment across 23 population samples in 20 countries participating in the BOLD Study between 2003 and 2012. METHODS: A false positive diagnosis of COPD was considered when participants reported a doctor's diagnosis of COPD, but postbronchodilator spirometry was unobstructed (FEV1/FVC > LLN). Additional analyses were performed using the fixed ratio criterion (FEV1/FVC

Published
2019

47. A pooled analysis of FEV(sub 1) decline in COPD patients randomized to inhaled corticosteroids or placebo

Author

Soriano, Joan B., Sin, Don D., Zhang, Xuekui, Camp, Pat G., Anderson, Julie A., Anthonisen, Nick R., Buist, A. Sonia, Burge, P. Sherwood, Calverley, Peter M., Connett, John E., Petersson, Stefan, Postma, Dirkje S., Szafranski, Wojciech, and Vestbo, Jorgen

Subjects
Forced expiratory volume -- Analysis, Lung diseases, Obstructive -- Care and treatment, Lung diseases, Obstructive -- Patient outcomes, Lung diseases, Obstructive -- Research, Corticosteroids -- Research, Health
Published
2007

49. Self-reported food reactions and their associations with asthma

Author

Emery, Nancy L., Vollmer, William M., Buist, A. Sonia, and Osborne, Molly L.

Subjects
Asthmatics -- Research -- Health aspects, Food -- Health aspects -- Research, Food allergy -- Research, Health, Health care industry, Research, Health aspects
Abstract

The role of food reactions in asthma has not been well described The objectives of this study were to evaluate the types of self-reported reactions to foods in asthmatic patients, [...]

Published
1996

50. Testing bronchodilator responsiveness

Author

Janson, Christer, Malinovschi, Andrei, Amaral, Andre F. S., Accordini, Simone, Bousquet, Jean, Buist, A. Sonia, Garcia-Aymerich, Judith, Gnatiuc, Louisa, Tan, Wan, Toren, Kjell, Zuberbier, Torsten, Burney, Peter, Janson, Christer, Malinovschi, Andrei, Amaral, Andre F. S., Accordini, Simone, Bousquet, Jean, Buist, A. Sonia, Garcia-Aymerich, Judith, Gnatiuc, Louisa, Tan, Wan, Toren, Kjell, Zuberbier, Torsten, and Burney, Peter

Published
2019
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