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1. Minimalistic Hybrid Approach for the Percutaneous Treatment of Coronary Chronic Total Occlusions: Midterm Follow-Up of an International Multicenter Cohort

Author

Castaldi, Gianluca, Kovacic, Mihajlo, Poletti, Enrico, Benedetti, Alice, Moroni, Alice, Scott, Benjamin, Wilgenhof, Adriaan, Bezzeccheri, Andrea, Vescovo, Giovanni, Budassi, Simone, El Jattari, Hicham, Convens, Carl, Verheye, Stefan, Vermeersch, Paul, Zivelonghi, Carlo, Tumscitz, Carlo, and Agostoni, Pierfrancesco

Published
2024
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2. Sex-specific features of optical coherence tomography detected plaque vulnerability related to clinical outcomes: insights from the CLIMA study

Author

Biccirè, Flavio Giuseppe, Debelak, Caterina, Varricchione, Giuseppe, Budassi, Simone, Gatto, Laura, Romagnoli, Enrico, Di Pietro, Riccardo, Sammartini, Emanuele, Marco, Valeria, Paoletti, Giulia, Burzotta, Francesco, Ozaki, Yukio, Pastori, Daniele, Alfonso, Fernando, Arbustini, Eloisa, and Prati, Francesco

Published
2023
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4. The Role of the Association Between Serum C-Reactive Protein Levels and Coronary Plaque Macrophage Accumulation in Predicting Clinical Events — Results from the CLIMA Registry

Author

Budassi, Simone, Biccirè, Flavio Giuseppe, Paoletti, Giulia, Marco, Valeria, Boi, Alberto, Romagnoli, Enrico, Fabbiocchi, Franco, Fineschi, Massimo, Di Pietro, Riccardo, Versaci, Francesco, Calligaris, Giuseppe, Gatto, Laura, Albertucci, Mario, Ramazzotti, Vito, Burzotta, Francesco, Ozaki, Yukio, Arbustini, Eloisa, Alfonso, Fernando, and Prati, Francesco

Published
2022
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5. Adoption of a new automated optical coherence tomography software to obtain a lipid plaque spread-out plot

Author

Isidori, Francesco, Lella, Eugenio, Marco, Valeria, Albertucci, Mario, Ozaki, Yukio, La Manna, Alessio, Biccirè, Flavio Giuseppe, Romagnoli, Enrico, Bourantas, Christos V., Paoletti, Giulia, Fabbiocchi, Franco, Gatto, Laura, Budassi, Simone, Sticchi, Alessandro, Burzotta, Francesco, Taglieri, Nevio, Calligaris, Giuseppe, Arbustini, Eloisa, Alfonso, Fernando, and Prati, Francesco

Published
2021
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7. Prevalence and quantitative assessment of macrophages in coronary plaques

Author

Gatto, Laura, Paoletti, Giulia, Marco, Valeria, La Manna, Alessio, Fabbiocchi, Franco, Cortese, Bernardo, Vergallo, Rocco, Boi, Alberto, Fineschi, Massimo, Di Giorgio, Alessandro, Taglieri, Nevio, Calligaris, Giuseppe, Budassi, Simone, Burzotta, Francesco, Isidori, Francesco, Lella, Eugenio, Ruscica, Giovanni, Albertucci, Mario, Tamburino, Corrado, Ozaki, Yukio, Alfonso, Fernando, Arbustini, Eloisa, and Prati, Francesco

Published
2021
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8. Contributors

Author

Agostoni, Pierfrancesco, primary, Landesberg, Amir, additional, Balkan, Wayne, additional, Banerjee, Monisha, additional, Banks, C. Adam, additional, Barac, Yaron, additional, Barker, Colin M., additional, Bejjanki, Harini, additional, Besola, Laura, additional, Bouten, C.V.C., additional, Bridges, Charles R, additional, Budassi, Simone, additional, Burkhoff, Daniel, additional, Burzotta, Francesco, additional, Cherian, Tharian S., additional, Chour, Tony, additional, Christman, Karen L., additional, Cleveland, David, additional, Colli, Andrea, additional, Cooper, David K.C., additional, Davis, Darryl R, additional, Ekser, Burcin, additional, Fargnoli, Anthony S, additional, Fiocco, Alessandro, additional, Folino, Giulio, additional, Gössl, Mario, additional, Garbutt, Tiffany A., additional, Gerosa, Gino, additional, Gheorghe, Livia, additional, Gubara, Sarah M, additional, Hahn, Rebecca T., additional, Hajjar, Roger J, additional, Hamid, Nadira, additional, Hara, Hidetaka, additional, Hare, Joshua M., additional, Hochman-Mendez, Camila, additional, Iwase, Hayato, additional, Jebran, Ahmad-Fawad, additional, Katz, Michael G, additional, Kazory, Amir, additional, Kliger, Chad, additional, Klouda, L., additional, Koratala, Abhilash, additional, Kutschka, Ingo, additional, Lee, Po-Feng, additional, Lenneman, Andrew J., additional, Lilly, Scott M., additional, Liu, Jiandong, additional, Lurier, E.B., additional, Marbán, Eduardo, additional, Nadali, Matteo, additional, Neofytou, Evgenios, additional, Nijenhuis, Vincent J, additional, Pagani, Francis D., additional, Pirelli, Luigi, additional, Prabhu, Sumanth D., additional, Pradegan, Nicola, additional, Qian, Li, additional, Rajapreyar, Indranee N., additional, Reardon, Michael J., additional, Russo, Giulio, additional, Sampaio, Luiz C., additional, Sorajja, Paul, additional, Tang, Liang, additional, Taylor, Doris A., additional, Topaz, Guy, additional, Trani, Carlo, additional, Trapana, Justin, additional, Tung, Roderick, additional, Nussinovitch, Udi, additional, Upadhyay, Gaurav A., additional, Uzendu, Anezi, additional, van der Heyden, Jan, additional, Vigliani, Marguerite B., additional, Wang, Raymond M., additional, Watt, Tessa M.F., additional, Wu, Joseph C., additional, Feld, Yair, additional, Zimmermann, Wolfram-Hubertus, additional, and Zivelonghi, Carlo, additional

Published
2020
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11. Clinical impact of OCT-derived suboptimal stent implantation parameters and definitions.

Author

Romagnoli, Enrico, Burzotta, Francesco, Vergallo, Rocco, Gatto, Laura, Biondi-Zoccai, Giuseppe, Ramazzotti, Vito, Biccirè, Flavio, Budassi, Simone, Trani, Carlo, Ali, Ziad, Stone, Gregg W, and Prati, Francesco

Subjects
PERCUTANEOUS coronary intervention, DRUG-eluting stents, MULTIVARIATE analysis, RETROSPECTIVE studies, TREATMENT effectiveness, COMPARATIVE studies, OPTICAL coherence tomography, RESEARCH funding, COMPLICATIONS of prosthesis, PROPORTIONAL hazards models
Abstract

Aims Despite growing evidence supporting the clinical utility of optical coherence tomography (OCT) guidance during percutaneous coronary interventions (PCIs), there is no common agreement as to the optimal stent implantation parameters that enhance clinical outcome. Methods and results We retrospectively examined the predictive accuracy of suboptimal stent implantation definitions proposed from the CLI-OPCI II, ILUMIEN-IV OPTIMAL PCI, and FORZA studies for the long-term risk of device-oriented cardiovascular events (DoCE) in the population of large all-comers CLI-OPCI project. A total of 1020 patients undergoing OCT-guided drug-eluting stent implantation in the CLI-OPCI registry with a median follow-up of 809 (quartiles 414–1376) days constituted the study population. According to CLI-OPCI II, ILUMIEN-IV OPTIMAL PCI, and FORZA criteria, the incidence of suboptimal stent implantation was 31.8%, 58.1%, and 57.8%, respectively. By multivariable Cox analysis, suboptimal stent implantation criteria from the CLI-OPCI II [hazard ratio 2.75 (95% confidence interval 1.88–4.02), P < 0.001] and ILUMIEN-IV OPTIMAL PCI [1.79 (1.18–2.71), P = 0.006] studies, but not FORZA trial [1.11 (0.75–1.63), P = 0.597], were predictive of DoCE. At long-term follow-up, stent edge disease with minimum lumen area <4.5 mm2 [8.17 (5.32–12.53), P < 0.001], stent edge dissection [2.38 (1.33–4.27), P = 0.004], and minimum stent area <4.5 mm2 [1.68 (1.13–2.51), P = 0.011] were the main OCT predictors of DoCE. Conclusion The clinical utility of OCT-guided PCI might depend on the metrics adopted to define suboptimal stent implantation. Uncovered disease at the stent border, stent edge dissection, and minimum stent area <4.5 mm2 were the strongest OCT associates of stent failure. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment Guidance

Author

Viscusi, Michele Mattia, primary, La Porta, Ylenia, additional, Migliaro, Giuseppe, additional, Gargano, Gian Marco, additional, Nusca, Annunziata, additional, Gatto, Laura, additional, Budassi, Simone, additional, Paolucci, Luca, additional, Mangiacapra, Fabio, additional, Ricottini, Elisabetta, additional, Melfi, Rosetta, additional, Rinaldi, Raffaele, additional, Prati, Francesco, additional, Ussia, Gian Paolo, additional, and Grigioni, Francesco, additional

Published
2023
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13. Clinical Impact of OCT-Derived Suboptimal Stent Implantation Parameters and Definitions

Author

Romagnoli, Enrico, Burzotta, Francesco, Vergallo, Rocco, Gatto, Laura, Biondi-Zoccai, Giuseppe, Ramazzotti, Vito, Biccirè, Flavio, Budassi, Simone, Trani, Carlo, Ali, Ziad, Stone, Gregg W, Prati, Francesco, Burzotta, Francesco (ORCID:0000-0002-6569-9401), Trani, Carlo (ORCID:0000-0001-9777-013X), Romagnoli, Enrico, Burzotta, Francesco, Vergallo, Rocco, Gatto, Laura, Biondi-Zoccai, Giuseppe, Ramazzotti, Vito, Biccirè, Flavio, Budassi, Simone, Trani, Carlo, Ali, Ziad, Stone, Gregg W, Prati, Francesco, Burzotta, Francesco (ORCID:0000-0002-6569-9401), and Trani, Carlo (ORCID:0000-0001-9777-013X)

Abstract

Aims: Despite growing evidence supporting the clinical utility of optical coherence tomography (OCT)-guidance during percutaneous coronary interventions (PCIs), there is no common agreement as to the optimal stent implantation parameters that enhance clinical outcome. Methods and results: We retrospectively examined the predictive accuracy of suboptimal stent implantation definitions proposed from the CLI-OPCI II, ILUMIEN-IV OPTIMAL PCI, and FORZA studies for the long-term risk of device oriented cardiovascular events (DoCE) in the population of large all-comers CLI-OPCI project.A total of 1020 patients undergoing OCT-guided drug-eluting stent implantation in the CLI-OPCI registry with a median follow-up of 809 (quartiles 414-1376) days constituted the study population. According to CLI-OPCI II, ILUMIEN-IV OPTIMAL PCI, and FORZA criteria, the incidence of suboptimal stent implantation was31.8%, 58.1%, and 57.8%, respectively. By multivariable Cox analysis, suboptimal stent implantation criteria from the CLI-OPCI II (hazard ratio 2.75 [95% confidence interval 1.88-4.02], p<0.001) and ILUMIEN-IV OPTIMAL PCI (1.79 [1.18-2.71], p=0.006) studies, but not FORZA trial (1.11 [0.75-1.63], p=0.597), were predictive of DoCE. At long-term follow-up, stent edge disease with minimum lumen area <4.5mm2 (8.17 [5.32-12.53], p<0.001), stent edge dissection (2.38 [1.33-4.27], p=0.004) and minimum stent area <4.5mm2 (1.68 [1.13-2.51], p=0.011) were the main OCT predictors of DoCE. Conclusion: The clinical utility of OCT-guided PCI might depend on the metrics adopted to define suboptimal stent implantation. Uncovered disease at the stent border, stent edge dissection, and minimum stent area <4.5mm2 were the strongest OCT associates of stent failure.

Published
2023

14. Sex-specific features of optical coherence tomography detected plaque vulnerability related to clinical outcomes: insights from the CLIMA study

Author

Biccirè, Flavio Giuseppe, primary, Debelak, Caterina, additional, Varricchione, Giuseppe, additional, Budassi, Simone, additional, Gatto, Laura, additional, Romagnoli, Enrico, additional, Di Pietro, Riccardo, additional, Sammartini, Emanuele, additional, Marco, Valeria, additional, Paoletti, Giulia, additional, Burzotta, Francesco, additional, Ozaki, Yukio, additional, Pastori, Daniele, additional, Alfonso, Fernando, additional, Arbustini, Eloisa, additional, and Prati, Francesco, additional

Published
2022
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15. 145 PREDICTION OF NEW ONSET ATRIAL FIBRILLATION IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PERCUTANEOUS CORONARY INTERVENTION USING THE C2HEST AND MC2HEST SCORES A REPORT FROM THE MULTICENTER REALE-ACS REGISTRY

Author

Gelfusa, Martina, primary, Biccirè, Flavio Giuseppe, additional, Tanzilli, Gaetano, additional, Prati, Francesco, additional, Sammartini, Emanuele, additional, Celeski, Mihail, additional, Budassi, Simone, additional, Barillà, Francesco, additional, Lip, Gregory Y H, additional, and Pastori, Daniele, additional

Published
2022
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16. 42 SEASON VARIABILITY IN ATHEROSCLEROSIS COMPOSITION: INSIGHTS FROM 1848 NON-CULPRIT CORONARY PLQUES

Author

Sammartini, Emanuele, primary, Biccirè, Flavio Giuseppe, additional, Debelak, Caterina, additional, La Porta, Ylenia, additional, Budassi, Simone, additional, Varricchione, Giuseppe, additional, Romagnoli, Enrico, additional, Marco, Valeria, additional, Boi, Alberto, additional, Fineschi, Massimo, additional, Fabbiocchi, Franco, additional, Taglieri, Nevio, additional, Calligaris, Giuseppe, additional, Ozaki, Yukio, additional, Arbustini, Eloisa, additional, Alfonso, Fernando, additional, and Prati, Francesco, additional

Published
2022
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18. TCT-237 Clinical Effectiveness of Functional Assessment of Non-Culprit Coronary Lesions Using an Optical Coherence Tomography Computational Algorithm: A CLIMA Post-Hoc Analysis

Author

Biccirè, Flavio Giuseppe, primary, Di Pietro, Riccardo, additional, Debelak, Caterina, additional, Boi, Alberto, additional, Bourantas, Christos, additional, Budassi, Simone, additional, Varricchione, Giuseppe, additional, Sammartini, Emanuele, additional, Versaci, Francesco, additional, Fabbiocchi, Franco, additional, Burzotta, Francesco, additional, Ozaki, Yukio, additional, Arbustini, Eloisa, additional, Alfonso, Fernando, additional, and Prati, Francesco, additional

Published
2022
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19. Optical coherence tomography-derived lipid core burden index and clinical outcomes: results from the CLIMA registry

Author

Biccirè, Flavio Giuseppe, primary, Budassi, Simone, additional, Ozaki, Yukio, additional, Boi, Alberto, additional, Romagnoli, Enrico, additional, Di Pietro, Riccardo, additional, Bourantas, Christos V, additional, Marco, Valeria, additional, Paoletti, Giulia, additional, Debelak, Caterina, additional, Sammartini, Emanuele, additional, Versaci, Francesco, additional, Fabbiocchi, Franco, additional, Burzotta, Francesco, additional, Pastori, Daniele, additional, Crea, Filippo, additional, Arbustini, Eloisa, additional, Alfonso, Fernando, additional, and Prati, Francesco, additional

Published
2022
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20. Clinical outcomes of suboptimal stent deployment as assessed by optical coherence tomography: long-term results of the CLI-OPCI registry

Author

Prati, Francesco, primary, Romagnoli, Enrico, additional, Biccirè, Flavio Biccirè, additional, Burzotta, Francesco, additional, La Manna, Alessio, additional, Budassi, Simone, additional, Ramazzotti, Vito, additional, Albertucci, Mario, additional, Fabbiocchi, Franco, additional, Sticchi, Alessandro, additional, Trani, Carlo, additional, Calligaris, Giuseppe, additional, Fineschi, Massimo, additional, Versaci, Francesco, additional, Tamburino, Corrado, additional, Ozaki, Yukio, additional, Alfonso, Fernando, additional, and Mintz, Gary Mintz, additional

Published
2022
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22. Sex-specific features of optical coherence tomography detected plaque vulnerability related to clinical outcomes: insights from the CLIMA study

Author

Biccirè, Flavio Giuseppe, Debelak, Caterina, Varricchione, Giuseppe, Budassi, Simone, Gatto, Laura, Romagnoli, Enrico, Di Pietro, Riccardo, Sammartini, Emanuele, Marco, Valeria, Paoletti, Giulia, Burzotta, Francesco, Ozaki, Yukio, Pastori, Daniele, Alfonso, Fernando, Arbustini, Eloisa, Prati, Francesco, Burzotta, Francesco (ORCID:0000-0002-6569-9401), Biccirè, Flavio Giuseppe, Debelak, Caterina, Varricchione, Giuseppe, Budassi, Simone, Gatto, Laura, Romagnoli, Enrico, Di Pietro, Riccardo, Sammartini, Emanuele, Marco, Valeria, Paoletti, Giulia, Burzotta, Francesco, Ozaki, Yukio, Pastori, Daniele, Alfonso, Fernando, Arbustini, Eloisa, Prati, Francesco, and Burzotta, Francesco (ORCID:0000-0002-6569-9401)

Abstract

Purpose: To investigate the different impact of optical coherence tomography (OCT)-derived vulnerable plaque features on future adverse events (AEs) according to the biological sex. Methods: The prospective multicenter CLIMA study (ClinicalTrials.gov: NCT02883088) enrolled 1003 patients with OCT plaque analysis of non-treated coronary plaques located in the proximal left anterior descending artery. Sex-specific differences in plaque composition and vulnerable features were described. We investigated the incidence of AEs, including cardiac death, any myocardial infarction and target vessel revascularization at 1-year. Results: Among 1003 patients, 24.6% were women. Women were older and more frequently affected by chronic kidney disease. Dyslipidemia, prior MI and smoking habit were more common in men. At OCT analysis, women had shorter plaque length (p <0.001), ticker fibrous cap (p = 0.001), smaller maximum lipid arc (p =0.019), lower macrophage infiltration (p <0.001) and intra-plaque layered tissue (p =0.007). During follow-up, 65 AEs were registered. The presence of a thin fibrous cap and a large macrophage infiltration (>67 degrees) predicted AEs in both sexes. The presence of macrophages (HR 3.38, p =0.018) and a small minimum lumen area (HR 4.97, p =0.002) were associated with AEs in women but not in men, while a large lipid arc (> 180 degrees) was associated with AEs in men (HR 2.56, p =0.003) but not in women. Conclusion: This subanalysis of the CLIMA study investigated for the first-time sex-specific OCT features of plaque vulnerability associated with AEs. Local inflammation was associated with AEs in women and a large lipid arc was predictive in men. OCT may help develop sex-specific risk stratification strategies.

Published
2022

23. Optical coherence tomography-derived lipid core burden index and clinical outcomes: results from the CLIMA registry

Author

Biccirè, Flavio Giuseppe, Budassi, Simone, Ozaki, Yukio, Boi, Alberto, Romagnoli, Enrico, Di Pietro, Riccardo, Bourantas, Christos V, Marco, Valeria, Paoletti, Giulia, Debelak, Caterina, Sammartini, Emanuele, Versaci, Francesco, Fabbiocchi, Franco, Burzotta, Francesco, Pastori, Daniele, Crea, Filippo, Arbustini, Eloisa, Alfonso, Fernando, Prati, Francesco, Burzotta, Francesco (ORCID:0000-0002-6569-9401), Crea, Filippo (ORCID:0000-0001-9404-8846), Biccirè, Flavio Giuseppe, Budassi, Simone, Ozaki, Yukio, Boi, Alberto, Romagnoli, Enrico, Di Pietro, Riccardo, Bourantas, Christos V, Marco, Valeria, Paoletti, Giulia, Debelak, Caterina, Sammartini, Emanuele, Versaci, Francesco, Fabbiocchi, Franco, Burzotta, Francesco, Pastori, Daniele, Crea, Filippo, Arbustini, Eloisa, Alfonso, Fernando, Prati, Francesco, Burzotta, Francesco (ORCID:0000-0002-6569-9401), and Crea, Filippo (ORCID:0000-0001-9404-8846)

Abstract

N/A

Published
2022

24. Optical coherence tomography-derived lipid core burden index and clinical outcomes: results from the CLIMA registry.

Author

Biccirè, Flavio Giuseppe, Budassi, Simone, Ozaki, Yukio, Boi, Alberto, Romagnoli, Enrico, Pietro, Riccardo Di, Bourantas, Christos V, Marco, Valeria, Paoletti, Giulia, Debelak, Caterina, Sammartini, Emanuele, Versaci, Francesco, Fabbiocchi, Franco, Burzotta, Francesco, Pastori, Daniele, Crea, Filippo, Arbustini, Eloisa, Alfonso, Fernando, and Prati, Francesco

Subjects
RESEARCH, SCIENTIFIC observation, CONFIDENCE intervals, MANN Whitney U Test, T-test (Statistics), OPTICAL coherence tomography, CORONARY artery disease, DESCRIPTIVE statistics, CHI-squared test, KAPLAN-Meier estimator, RESEARCH funding, DATA analysis software, ODDS ratio, LONGITUDINAL method, SECONDARY analysis
Abstract

Aims The aim of this study was to assess the morphological characteristics and prognostic implications of the optical coherence tomography (OCT)-derived lipid core burden index (LCBI). Methods and results OCT-LCBI was assessed in 1003 patients with 1-year follow-up from the CLIMA multicentre registry using a validated software able to automatically obtain a maximum OCT-LCBI in 4 mm (maxOCT-LCBI4mm). Primary composite clinical endpoint included cardiac death, myocardial infarction, and target-vessel revascularization. A secondary analysis using clinical outcomes of CLIMA study was performed. Patients with a maxOCT-LCBI4mm ≥ 400 showed higher prevalence of fibrous cap thickness (FCT) <75 μm [odds ratio (OR) 1.43, 95% confidence interval (CI) 1.03–1.99; P = 0.034], lipid pool arc >180° (OR 3.93, 95%CI 2.97–5.21; P < 0.001), minimum lumen area <3.5 mm2 (OR 1.5, 95%CI 1.16–1.94; P = 0.002), macrophage infiltration (OR 2.38, 95%CI 1.81–3.13; P < 0.001), and intra-plaque intimal vasculature (OR 1.34, 95%CI 1.05–1.72; P = 0.021). A maxOCT-LCBI4mm ≥400 predicted the primary endpoint [adjusted hazard ratio (HR) 1.86, 95%CI 1.1–3.2; P = 0.019] as well as the CLIMA endpoint (HR 2.56, 95%CI 1.24–5.29; P = 0.011). Patients with high lipid content and thin FCT < 75 µm were at higher risk for adverse events (HR 4.88, 95%CI 2.44–9.72; P < 0.001). Conclusions A high maxOCT-LCBI4mm was related to poor outcome and vulnerable plaque features. This study represents a step further in the automated assessment of the coronary plaque risk profile. [ABSTRACT FROM AUTHOR]

Published
2023
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26. Relationship betweeen the amount and location of macrophages and clinical outcome: subanalysis of the CLIMA-study

Author

Gatto, Laura, primary, Alfonso, Fernando, additional, Paoletti, Giulia, additional, Burzotta, Francesco, additional, La Manna, Alessio, additional, Budassi, Simone, additional, Biccirè, Flavio Giuseppe, additional, Fineschi, Massimo, additional, Marco, Valeria, additional, Fabbiocchi, Franco, additional, Vergallo, Rocco, additional, Boi, Alberto, additional, Ruscica, Giovanni, additional, Versaci, Francesco, additional, Taglieri, Nevio, additional, Calligaris, Giuseppe, additional, Albertucci, Mario, additional, Romagnoli, Enrico, additional, Ramazzotti, Vito, additional, Tamburino, Corrado, additional, Crea, Filippo, additional, Ozaki, Yukio, additional, Arbustini, Eloisa, additional, and Prati, Francesco, additional

Published
2022
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27. 233 Prognostic implications of the automated detection of lipid core burden index at optical coherence tomography: post hoc analysis of the CLIMA study

Author

Biccirè, Flavio Giuseppe, primary, Budassi, Simone, additional, Isidori, Francesco, additional, Lella, Eugenio, additional, Romagnoli, Enrico, additional, Albertucci, Mario, additional, Paoletti, Giulia, additional, Manna, Alessio La, additional, Boi, Alberto, additional, Burzotta, Francesco, additional, Ozaki, Yukio, additional, Mintz, Gary S, additional, Alfonso, Fernando, additional, and Prati, Francesco, additional

Published
2021
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28. TCT-88 Relationship Between the Amount and Location of Macrophages and Clinical Outcome: Subanalysis of the CLIMA Study

Author

Budassi, Simone, primary, Biccirè, Flavio, additional, Gatto, Laura, additional, Alfonso, Fernando, additional, Paoletti, Giulia, additional, Burzotta, Francesco, additional, La Manna, Alessio, additional, Fineschi, Massimo, additional, Marco, Valeria, additional, Fabbiocchi, Franco, additional, Vergallo, Rocco, additional, Boi, Alberto, additional, Ruscica, Giovanni, additional, Versaci, Francesco, additional, Taglieri, Nevio, additional, Calligaris, Giuseppe, additional, Albertucci, Mario, additional, Romagnoli, Enrico, additional, Ramazzptto, Vito, additional, Tamburino, Corrado, additional, Crea, Filippo, additional, Ozaki, Yukio, additional, Arbustini, Eloisa, additional, and Prati, Francesco, additional

Published
2021
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29. TCT-80 Feasibility and Prognostic Meaning of the Automated Detection of Lipid Core Burden Index at Optical Coherence Tomography: Post Hoc Analysis of the CLIMA Study

Author

Biccirè, Flavio, primary, Budassi, Simone, additional, Isidori, Francesc, additional, Lella, Eugenio, additional, Marco, Valeria, additional, Albertucci, Mario, additional, Ozaki, Yukio, additional, La Manna, Alessio, additional, Romagnoli, Enrico, additional, Bourantas, Christos, additional, Paoletti, Giulia, additional, Fabbiocchi, Franco, additional, Gatto, Laura, additional, Sticchi, Alessandro, additional, Burzotta, Francesco, additional, Taglieri, Nevio, additional, Calligaris, Giuseppe, additional, Arbustini, Eloisa, additional, Alfonso, Fernando, additional, and Prati, Francesco, additional

Published
2021
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32. Impact of prior coronary artery bypass grafting in patients undergoing chronic total occlusion-percutaneous coronary intervention: Procedural and clinical outcomes from the REgistry of Crossboss and Hybrid procedures in FrAnce, the NetheRlands, BelGium, and UnitEd Kingdom (RECHARGE)

Author

Budassi, Simone, Zivelonghi, Carlo, Dens, Joseph, Bagnall, Alan J., Knaapen, Paul, Avran, Alexandre, Spratt, James C., Walsh, Simon, Faurie, Benjamin, Agostoni, Pierfrancesco, Cardiology, and ACS - Atherosclerosis & ischemic syndromes

Subjects
surgical procedures, operative, cardiovascular diseases
Abstract

Aim: Chronic total occlusions (CTO) in patients with history of coronary artery bypass graft (CABG) show more advanced and complex atherosclerotic pathology. Aim of our study is to compare outcomes in patients undergoing CTO percutaneous coronary intervention (PCI) with previous CABG versus those without in the REgistry of Crossboss and Hybrid procedures in FrAnce the NetheRlands, BelGium and UnitEd Kingdom (RECHARGE). Methods & results: The RECHARGE cohort (1,252 patients) was divided in two groups according to the presence of previous CABG (217) or not. We also focused, in the post-CABG group, on a comparison between CTO in previously grafted vessels versus non-grafted vessels. The CTO complexity scores were higher and the success rate (71.9% vs. 88.7%, p

Published
2021

33. Clinical outcomes of suboptimal stent deployment as assessed by optical coherence tomography: long-term results of the CLI-OPCI registry

Author

Prati, Francesco, Romagnoli, Enrico, Biccirè, Flavio Giuseppe, Burzotta, Francesco, La Manna, Alessio, Budassi, Simone, Ramazzotti, Vito, Albertucci, Mario, Fabbiocchi, Franco, Sticchi, Alessandro, Trani, Carlo, Calligaris, Giuseppe, Fineschi, Massimo, Versaci, Francesco, Tamburino, Corrado, Ozaki, Yukio, Alfonso, Fernando, Mintz, Gary S, Burzotta, Francesco (ORCID:0000-0002-6569-9401), Trani, Carlo (ORCID:0000-0001-9777-013X), Prati, Francesco, Romagnoli, Enrico, Biccirè, Flavio Giuseppe, Burzotta, Francesco, La Manna, Alessio, Budassi, Simone, Ramazzotti, Vito, Albertucci, Mario, Fabbiocchi, Franco, Sticchi, Alessandro, Trani, Carlo, Calligaris, Giuseppe, Fineschi, Massimo, Versaci, Francesco, Tamburino, Corrado, Ozaki, Yukio, Alfonso, Fernando, Mintz, Gary S, Burzotta, Francesco (ORCID:0000-0002-6569-9401), and Trani, Carlo (ORCID:0000-0001-9777-013X)

Abstract

N/A

Published
2021

39. Prevalence and quantitative assessment of macrophages in coronary plaques

Author

Gatto, Laura, primary, Paoletti, Giulia, additional, Marco, Valeria, additional, La Manna, Alessio, additional, Fabbiocchi, Franco, additional, Cortese, Bernardo, additional, Vergallo, Rocco, additional, Boi, Alberto, additional, Fineschi, Massimo, additional, Di Giorgio, Alessandro, additional, Taglieri, Nevio, additional, Calligaris, Giuseppe, additional, Budassi, Simone, additional, Burzotta, Francesco, additional, Isidori, Francesco, additional, Lella, Eugenio, additional, Ruscica, Giovanni, additional, Albertucci, Mario, additional, Tamburino, Corrado, additional, Ozaki, Yukio, additional, Alfonso, Fernando, additional, Arbustini, Eloisa, additional, and Prati, Francesco, additional

Published
2020
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41. Impact of environmental pollution and weather changes on the incidence of ST-elevation myocardial infarction

Author

Biondi-Zoccai, Giuseppe, primary, Frati, Giacomo, additional, Gaspardone, Achille, additional, Mariano, Enrica, additional, Di Giosa, Alessandro D, additional, Bolignano, Andrea, additional, Dei Giudici, Angela, additional, Calcagno, Simone, additional, Scappaticci, Massimiliano, additional, Sciarretta, Sebastiano, additional, Valenti, Valentina, additional, Casati, Rebecca, additional, Visconti, Giuseppe, additional, Penco, Maria, additional, Giannico, Maria B, additional, Peruzzi, Mariangela, additional, Cavarretta, Elena, additional, Budassi, Simone, additional, Cosma, Joseph, additional, Federici, Massimo, additional, Roever, Leonardo, additional, Romeo, Francesco, additional, and Versaci, Francesco, additional

Published
2020
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43. Impact of environmental pollution and weather changes on the incidence of ST-elevation myocardial infarction.

Author

Biondi-Zoccai, Giuseppe, Frati, Giacomo, Gaspardone, Achille, Mariano, Enrica, Di Giosa, Alessandro D., Bolignano, Andrea, Dei Giudici, Angela, Calcagno, Simone, Scappaticci, Massimiliano, Sciarretta, Sebastiano, Valenti, Valentina, Casati, Rebecca, Visconti, Giuseppe, Penco, Maria, Giannico, Maria B., Peruzzi, Mariangela, Cavarretta, Elena, Budassi, Simone, Cosma, Joseph, and Federici, Massimo

Published
2021
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46. TCT-102 Impact of Coronary Artery Bypass History in Patients Undergoing Chronic Total Occlusion-Percutaneous Coronary Intervention: Procedural and Clinical Outcomes from the Registry of CrossBoss and Hybrid Procedures in France, the Netherlands, Belgium, and United Kingdom (RECHARGE)

Author

Budassi, Simone, primary, Zivelonghi, Carlo, additional, Dens, Joseph, additional, Walsh, Simon, additional, Knaapen, Paul, additional, Avran, Alexandre, additional, Spratt, James, additional, and Agostoni, Pierfrancesco, additional

Published
2019
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48. MiR-423 is differentially expressed in patients with stable and unstable coronary artery disease: A pilot study

Author

Rizzacasa, Barbara, primary, Morini, Elena, additional, Mango, Ruggiero, additional, Vancheri, Chiara, additional, Budassi, Simone, additional, Massaro, Gianluca, additional, Maletta, Sara, additional, Macrini, Massimiliano, additional, D’Annibale, Silvio, additional, Romeo, Francesco, additional, Novelli, Giuseppe, additional, and Amati, Francesca, additional

Published
2019
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49. Selection of a “housekeeping” miRNA to normalize qRT-PCR data v1

Author

Rizzacasa, Barbara, primary, Morini, Elena, additional, Mango, Ruggiero, additional, Vancheri, Chiara, additional, Budassi, Simone, additional, Massaro, Gianluca, additional, Maletta, Sara, additional, Macrini, Massimiliano, additional, D’Annibale, Silvio, additional, Romeo, Francesco, additional, Novelli, Giuseppe, additional, and Amati, Francesca, additional

Published
2019
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50. Comparative Ct method quantification (2-ΔCt method). v1

Author

Rizzacasa, Barbara, primary, Morini, Elena, additional, Mango, Ruggiero, additional, Vancheri, Chiara, additional, Budassi, Simone, additional, Massaro, Gianluca, additional, Maletta, Sara, additional, Macrini, Massimiliano, additional, D’Annibale, Silvio, additional, Romeo, Francesco, additional, Novelli, Giuseppe, additional, and Amati, Francesca, additional

Published
2019
Full Text
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