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1. Safety of the PCSK9 inhibitor alirocumab: insights from 47 296 patient-years of observation

Author: Goodman, Shaun G, Steg, Philippe Gabriel, Szarek, Michael, Bhatt, Deepak L, Bittner, Vera A, Diaz, Rafael, Harrington, Robert A, Jukema, J Wouter, White, Harvey D, Zeiher, Andreas M, Manvelian, Garen, Pordy, Robert, Poulouin, Yann, Stipek, Wanda, Garon, Genevieve, Schwartz, Gregory G, Steg, Ph Gabriel, Tricoci, Pierluigi, Roe, Matthew T, Mahaffey, Kenneth W, Edelberg, Jay M, Hanotin, Corinne, Lecorps, Guillaume, Moryusef, Angèle, Sasiela, William J, Tamby, Jean-François, Aylward, Philip E, Drexel, Heinz, Sinnaeve, Peter, Dilic, Mirza, Lopes, Renato D, Gotcheva, Nina N, Prieto, Juan-Carlos, Yong, Huo, López-Jaramillo, Patricio, Pećin, Ivan, Reiner, Zeljko, Ostadal, Petr, Poulsen, Steen Hvitfeldt, Viigimaa, Margus, Nieminen, Markku S, Danchin, Nicolas, Chumburidze, Vakhtang, Marx, Nikolaus, Liberopoulos, Evangelos, Valdovinos, Pablo Carlos Montenegro, Tse, Hung-Fat, Kiss, Robert Gabor, Xavier, Denis, Zahger, Doron, Valgimigli, Marco, Kimura, Takeshi, Kim, Hyo Soo, Kim, Sang-Hyun, Erglis, Andrejs, Laucevicius, Aleksandras, Kedev, Sasko, Yusoff, Khalid, López, Gabriel Arturo Ramos, Alings, Marco, Halvorsen, Sigrun, Flores, Roger M Correa, Sy, Rody G, Budaj, Andrzej, Morais, Joao, Dorobantu, Maria, Karpov, Yuri, Ristic, Arsen D, Chua, Terrance, Murin, Jan, Fras, Zlatko, Dalby, Anthony J, Tuñón, José, de Silva, H Asita, Hagström, Emil, Landmesser, Ulf, Chiang, Chern-En, Sritara, Piyamitr, Guneri, Sema, Parkhomenko, Alexander, Ray, Kausik K, Moriarty, Patrick M, Chaitman, Bernard, Kelsey, Sheryl F, Olsson, Anders G, and Rouleau, Jean-Lucien
Subjects: Biomedical and Clinical Sciences, Clinical Sciences, Clinical Trials and Supportive Activities, Patient Safety, Clinical Research, 6.1 Pharmaceuticals, Good Health and Well Being, Humans, Antibodies, Monoclonal, Humanized, Anticholesteremic Agents, Biomarkers, Cardiovascular Diseases, Cholesterol, LDL, Dyslipidemias, PCSK9 Inhibitors, Proprotein Convertase 9, Randomized Controlled Trials as Topic, Serine Proteinase Inhibitors, Time Factors, Treatment Outcome, ODYSSEY OUTCOMES Investigators, Alirocumab, Cholesterol, PCSK9, Safety, Cardiorespiratory Medicine and Haematology, Pharmacology and Pharmaceutical Sciences, Cardiovascular medicine and haematology, Pharmacology and pharmaceutical sciences
Abstract: The ODYSSEY OUTCOMES trial, comprising over 47 000 patient-years of placebo-controlled observation, demonstrated important reductions in the risk of recurrent ischaemic cardiovascular events with the monoclonal antibody to proprotein convertase subtilisin/kexin type 9 alirocumab, as well as lower all-cause death. These benefits were observed in the context of substantial and persistent lowering of low-density lipoprotein cholesterol with alirocumab compared with that achieved with placebo. The safety profile of alirocumab was indistinguishable from matching placebo except for a ∼1.7% absolute increase in local injection site reactions. Further, the safety of alirocumab compared with placebo was evident in vulnerable groups identified before randomization, such as the elderly and those with diabetes mellitus, previous ischaemic stroke, or chronic kidney disease. The frequency of adverse events and laboratory-based abnormalities was generally similar to that in placebo-treated patients. Thus, alirocumab appears to be a safe and effective lipid-modifying treatment over a duration of at least 5 years.
Published: 2024

2. PM 1-322: new variable planetary nebula

Author: Paunzen, E., Bernhard, K., Budaj, J., Hambsch, F. -J., Hümmerich, S., Jones, D., and Krticka, J.
Subjects: Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract: Spectra of planetary nebulae (PNe) are characterised by strong forbidden emission lines and often also by an infrared (IR) excess. A few PNe show dust obscuration events and/or harbour long-period binaries. Some post-asymptotic giant branch stars, symbiotic stars, or B[e] stars may feature similar characteristics. Recently, dust clouds eclipsing white dwarfs were also detected. We report the discovery of an object with a very peculiar variability pattern that bears signatures compatible with the above-mentioned classes of objects. The object is ZTFJ201451.59+120353.4 and identifies with PM 1-322. The object was discovered in Zwicky Transient Facility archival data and investigated with historical and newly obtained photometric and spectroscopic observations. The ZTF r and g data show a one magnitude deep, eclipse-like event with a duration of about half a year that occurred in 2022. The variability pattern of the star is further characterised by several dimming events in the optical region that are accompanied by simultaneous brightenings in the red and IR regions. Apart from that, two fast eruption-like events were recorded in ZTF r data. Archival data from WISE indicate long-term variability with a possible period of 6 or 12 yr. Our follow-up time series photometry reveals a stochastic short-term variability with an amplitude of about 0.1 mag on a timescale of about one hour. The spectral energy distribution is dominated by IR radiation. Our high-resolution spectroscopy shows strong forbidden emission lines from highly ionised species and symmetric double-peaked emission in Halpha, which is very different from what is seen in earlier spectra obtained in 2007. Several explanatory scenarios are presented. Our most likely interpretation is that our target object involves a hot central star surrounded by gaseous and dusty disks, an extended nebula, and a possible companion star., Comment: 10 pages, 8 figures, 2 tables, accepted for publication in Astronomy & Astrophysics
Published: 2023
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3. Science with a small two-band UV-photometry mission II: Observations of stars and stellar systems

Author: Krtička, J., Benáček, J., Budaj, J., Korčáková, D., Pál, A., Piecka, M., Zejda, M., Bakış, V., Brož, M., Chang, Hsiang-Kuang, Faltová, N., Gális, R., Jadlovský, D., Janík, J., Kára, J., Kolář, J., Krtičková, I., Kubát, J., Kubátová, B., Kurfürst, P., Labaj, M., Merc, J., Mikulášek, Z., Münz, F., Paunzen, E., Prišegen, M., Ramezani, T., Rievajová, T., Řípa, J., Schmidtobreick, L., Skarka, M., Szász, G., Weiss, W., Zajaček, M., and Werner, N.
Subjects: Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Earth and Planetary Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: We outline the impact of a small two-band UV-photometry satellite mission on the field of stellar physics, magnetospheres of stars, binaries, stellar clusters, interstellar matter, and exoplanets. On specific examples of different types of stars and stellar systems, we discuss particular requirements for such satellite missions in terms of specific mission parameters such as bandpass, precision, cadence, and mission duration. We show that such a mission may provide crucial data not only for hot stars that emit most of their light in UV, but also for cool stars, where UV traces their activity. This is important, for instance, for exoplanetary studies, because the level of stellar activity influences habitability. While the main asset of the two-band UV mission rests in time-domain astronomy, an example of open clusters proves that such a mission would be important also for the study of stellar populations. Properties of the interstellar dust are best explored when combining optical and IR information with observations in UV. It is well known that dust absorbs UV radiation efficiently. Consequently, we outline how such a UV mission can be used to detect eclipses of sufficiently hot stars by various dusty objects and study disks, rings, clouds, disintegrating exoplanets or exoasteroids. Furthermore, UV radiation can be used to study the cooling of neutron stars providing information about the extreme states of matter in the interiors of neutron stars and used for mapping heated spots on their surfaces., Comment: Accepted for publication in Space Science Reviews; corrected version including comments of the referee
Published: 2023

4. Quick Ultra-VIolet Kilonova surveyor (QUVIK)

Author: Werner, N., Řípa, J., Münz, F., Hroch, F., Jelínek, M., Krtička, J., Zajaček, M., Topinka, M., Dániel, V., Gromeš, J., Václavík, J., Steiger, L., Lédl, V., Seginak, J., Benáček, J., Budaj, J., Faltová, N., Gális, R., Jadlovský, D., Janík, J., Kajan, M., Karas, V., Korčáková, D., Kosiba, M., Krtičková, I., Kubát, J., Kubátová, B., Kurfürst, P., Labaj, M., Mikulášek, Z., Pál, A., Paunzen, E., Piecka, M., Prišegen, M., Ramezani, T., Skarka, M., Szász, G., Thöne, C., and Zejda, M.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract: We present a near-UV space telescope on a ~70kg micro-satellite with a moderately fast repointing capability and a near real-time alert communication system that has been proposed in response to a call for an ambitious Czech national mission. The mission, which has recently been approved for Phase 0, A, and B1 study shall measure the brightness evolution of kilonovae, resulting from mergers of neutron stars in the near-UV band and thus it shall distinguish between different explosion scenarios. Between the observations of transient sources, the satellite shall perform observations of other targets of interest, a large part of which will be chosen in open competition., Comment: SPIE Astronomical Telescopes and Instrumentation
Published: 2022

5. Science with a Small Two-Band UV-Photometry Mission II: Observations of Stars and Stellar Systems

Author: Krtička, Jiří, Benáček, Jan, Budaj, Jan, Korčáková, Daniela, Pál, András, Piecka, Martin, Zejda, Miloslav, Bakış, Volkan, Brož, Miroslav, Chang, Hsiang-Kuang, Faltová, Nikola, Gális, Rudolf, Jadlovský, Daniel, Janík, Jan, Kára, Jan, Kolář, Jakub, Krtičková, Iva, Kubát, Jiří, Kubátová, Brankica, Kurfürst, Petr, Labaj, Matúš, Merc, Jaroslav, Mikulášek, Zdeněk, Münz, Filip, Paunzen, Ernst, Prišegen, Michal, Ramezani, Tahereh, Rievajová, Tatiana, Řípa, Jakub, Schmidtobreick, Linda, Skarka, Marek, Szász, Gabriel, Weiss, Werner, Zajaček, Michal, and Werner, Norbert
Published: 2024
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6. HD 183986: a high-contrast SB2 system with a pulsating component

Author: Vaňko, Martin, Pribulla, Theodor, Gajdoš, Pavol, Budaj, Ján, Zverko, Juraj, Paunzen, Ernst, Garai, Zoltán, Hambálek, Lubomír, Komžík, Richard, and Kundra, Emil
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: There is a small group of peculiar early-type stars on the main sequence that show different rotation velocities from different spectral lines. This inconsistency might be due to the binary nature of these objects. We aim to verify this hypothesis by a more detailed spectroscopic and photometric investigation of one such object: HD 183986. We obtained 151 high and medium resolution spectra that covered an anticipated long orbital period. There is clear evidence of theorbital motion of the primary component. We uncovered a very faint and broad spectrum of the secondary component. The corresponding SB2 orbital parameters, and the component spectra, were obtained by Fourier disentangling using the KOREL code. The component spectra were further modeled by iSpec code to arrive at the atmospheric quantities and the projected rotational velocities. We have proven that this object is a binary star with the period $P$ = 1268.2(11) d, eccentricity $e$ = 0.5728(20), and mass ratio $q$ = 0.655. The primary component is a slowly rotating star ($v \sin i = 27$ km.s$^{-1}$) while the cooler and less massive secondary rotates much faster ($v \sin i \sim 120$ km.s$^{-1}$). Photometric observations obtained by the TESS satellite were also investigated to shed more light on this object. A multi-period photometric variability was detected in the TESS data ranging from hours (the $\delta$ Sct-type variability) to a few days (spots/rotational variability). The physical parameters of the components and the origin of the photometric variability are discussed in more detail., Comment: Accepted to AJ. arXiv admin note: text overlap with arXiv:1307.2553 by other authors. text overlap with arXiv:1307.2553 by other authors
Published: 2022
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7. WD 1145+017: Alternative models of the atmosphere, dust clouds, and gas rings

Author: Budaj, Jan, Maliuk, Andrii, and Hubeny, Ivan
Subjects: Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract: WD 1145+017 is the first white dwarf known to be orbited by disintegrating exoasteroids. It is a DBZ-type white dwarf with strongly variable broad circumstellar lines and variable shallow UV transits. Various models of the dust clouds and gaseous rings have been proposed as an explanation for this behavior. Here we propose alternative models.The simple radiative transfer code Shellspec was modified for this purpose and used for testing the new dust cloud and gas disk models. We used modified TLUSTY and SYNSPEC codes to calculate atmosphere models assuming the LTE or NLTE, and to calculate the intrinsic spectrum of the star. We then used these atmosphere models to estimate the mass of the radiative and convective zones and NLTE spectrum synthesis to estimate their chemical composition. We offer an alternative explanation of some (not all) shallow UV transits. These may be naturally caused by the optical properties of the dust grains: opacities and mainly phase functions as a result of the forward scattering. The latter is much stronger in UV compared to the optical region, leaving more UV photons in the original direction during the transit. We also developed an alternative model of the gaseous disk, consisting of an inner, hotter, and almost circular disk and an outer, cooler, and eccentric disk. The structure precesses with a period of $3.83 \pm 0.12$ yr. We demonstrate that it fits the observed circumstellar lines reasonably well. These alternative models solve a few drawbacks that might be associated with the previous models, but they also have their own disadvantages. We confirm that the chemical composition of the atmosphere is similar to that of CI chondrites but C, N, and S are significantly underabundant and much closer to the bulk Earth composition. This is a strong argument that the star has recently encountered and accreted material from a body of Earth-like composition., Comment: Eqs.18, 19 in a more elegant form
Published: 2022
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8. Radial access versus distal radial access: the vote for use of ultrasonography?

Author: Bogumił Ramotowski, Anna Żuk, Paweł Lewandowski, Tomasz Słomski, Paweł Maciejewski, and Andrzej Budaj
Subjects: Medicine
Published: 2024
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9. Triglyceride Levels, Alirocumab Treatment, and Cardiovascular Outcomes After an Acute Coronary Syndrome

Author: Zahger, Doron, Schwartz, Gregory G., Du, Weiming, Szarek, Michael, Bhatt, Deepak L., Bittner, Vera A., Budaj, Andrzej J., Diaz, Rafael, Goodman, Shaun G., Jukema, J. Wouter, Kiss, Robert G., Harrington, Robert A., Moriarty, Patrick M., Scemama, Michel, Manvelian, Garen, Pordy, Robert, White, Harvey D., Zeiher, Andreas M., Fazio, Sergio, Geba, Gregory P., and Steg, Ph Gabriel
Published: 2024
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10. Platelet reactivity and activated clotting time predict hemorrhagic site complications in patients with chronic coronary syndromes undergoing percutaneous coronary interventions

Author: Ramotowski, Bogumił, Lewandowski, Paweł, Słomski, Tomasz, Maciejewski, Paweł, and Budaj, Andrzej
Published: 2024
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11. Looking into the cradle of the grave: J22564-5910, a young post-merger hot subdwarf?

Author: Vos, Joris, Pelisoli, Ingrid, Budaj, Jan, Reindl, Nicole, Schaffenroth, Veronika, Bobrick, Alexey, Geier, Stephan, Hermes, J. J., Nemeth, Peter, Østensen, Roy, Reding, Joshua S., Uzundag, Murat, and Vuckovic, Maja
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: We present the discovery of J22564-5910, a new type of hot subdwarf (sdB) which shows evidence of gas present in the system and has shallow, multi-peaked hydrogen and helium lines which vary in shape over time. All observational evidence points towards J22564-5910 being observed very shortly after the merger phase that formed it. Using high-resolution, high signal-to-noise spectroscopy, combined with multi-band photometry, Gaia astrometry, and TESS light curves, we aim to interpret these unusual spectral features. The photometry, spectra and light curves are all analyzed, and their results are combined in order to support our interpretation of the observations: the likely presence of a magnetic field combined with gas features around the sdB. Based on the triple-peaked H lines, the magnetic field strength is estimated and, by using the shellspec code, qualitative models of gas configurations are fitted to the observations. All observations can either be explained by a magnetic field of ~650 kG which enables the formation of a centrifugal magnetosphere, or a non-magnetic hot subdwarf surrounded by a circumstellar gas disk/torus. Both scenarios are not mutually exclusive and both can be explained by a recent merger. J22564-5910 is the first object of its kind. It is a rapidly spinning sdB with gas still present in the system. It is the first post-merger star observed this early after the merger event, and as such is very valuable system to test merger theories. If the magnetic field can be confirmed, it is not only the first magnetic sdB, but it hosts the strongest magnetic field ever found in a pre-white dwarf object. Thus, it could represent the long-sought for immediate ancestor of strongly magnetic WDs., Comment: 15 pages, 11 figures. Accepted for publication in A&A
Published: 2021
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12. Altered platelet reactivity, coagulation, endothelial and inflammatory markers early after smoking cessation verified with cotinine plasma concentration

Author: Ramotowski, Bogumił, Undas, Anetta, and Budaj, Andrzej
Published: 2023
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13. Shellspec39 -- a tool for modelling the spectra, light curves, and images of interacting binaries and exoplanets

Author: Budaj, Jan
Subjects: Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract: Program SHELLSPEC is designed to calculate light curves, spectra, and images of interacting binaries and extra-solar planets immersed in a moving gaseous or dusty circumstellar matter. It solves simple radiative transfer along the line of sight in 3D moving media. The Roche model and synthetic spectra from the stellar atmosphere models such as TLUSTY from Ivan Hubeny can be used as a boundary condition for the radiative transfer. The latest publicly available version is Shellspec39. The code has been combined with other methods such as Doppler tomography and interferometry and used to analyze spectroscopic, photometric, and interferometric observations of binary stars and transiting exoplanets. A few examples are briefly mentioned., Comment: Radiative Signatures from the Cosmos, ASP Conference Series, Vol. 519, Proceedings of a conference held 23-26 October, 2018 at Sorbonne University, Paris, France. Edited by K. Werner, C. Stehle, T. Rauch, and T. Lanz. San Francisco: Astronomical Society of the Pacific, 2019, p.87
Published: 2021

14. Optically thin circumstellar medium in $\beta$ Lyr A system

Author: Brož, M., Mourard, D., Budaj, J., Harmanec, P., Schmitt, H., Tallon-Bosc, I., Bonneau, D., Božić, H., Gies, D., and Šlechta, M.
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: beta Lyr A is a complex binary system with an extensive observational dataset: light curves (from FUV to FIR), interferometric squared visibility, closure phase, triple product measurements, spectral-energy distribution (SED), high-resolution spectroscopy, differential visibility amplitude, and also differential phase. In particular, we use spectra from Ondrejov 2m telescope from 2013 to 2015, to measure the emission in Halpha, HeI, SiII, NeI, or CII lines, and differential interferometry by CHARA/VEGA from the 2013 campaign to measure wavelength-dependent sizes across Halpha and HeI 6678. This allows us to constrain not only optically thick objects (primary, secondary, accretion disk), but also optically thin objects (disk atmosphere, jets, shell). We extended our modelling tool Pyshellspec (based on Shellspec; a 1D LTE radiative transfer code) to include all new observables, to compute differential visibilities/phases, to perform a Doppler tomography, and to determine a joint chi^2 metric. After an optimisation of 38 free parameters, we derive a robust model of the beta Lyr A system. According to the model, the emission is formed in an extended atmosphere of the disk, two perpendicular jets expanding at ~700 km s^-1, and a symmetric shell with the radius ~70 R_S. The spectroscopy indicates a low abundance of carbon, 10^-2 of the solar value. We also quantify systematic differences between datasets and discuss alternative models, with higher resolution, additional asymmetries, or He-rich abundance., Comment: 19 pages, 31 figures
Published: 2020
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15. Secular changes in the orbits of the quadruple system VW LMi

Author: Pribulla, T., Puha, E., Borkovits, T., Budaj, J., Garai, Z., Guenther, E., Hambalek, L., Komzik, R., Kundra, E., Szabo, Gy. M., and Vanko, M.
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: VW~LMi is the tightest known quadruple system with 2+2 hierarchy. It consists of a W UMa-type eclipsing binary (P12 = 0.47755 days) and another detached non-eclipsing binary (P34 = 7.93 days) orbiting around a common center of mass is about P1234 = 355 days. We present new observations of the system extending the time baseline to study long-term perturbations in the system and to improve orbital elements. The multi-dataset modeling of the system (4 radial-velocity curves for the components and the timing data) clearly showed an apsidal motion in the non-eclipsing binary at a rate of 4.6 degrees/yr, but no other perturbations. This is consistent with the nearly co-planarity of the outer, 355-day orbit, and the 7.93-day orbit of the non-eclipsing binary. Extensive N-body simulations enabled us to constrain the mutual inclination of the non-eclipsing binary and the outer orbits to j34-1234 < 10 degrees., Comment: 12 pages, 7 figures, MNRAS in press
Published: 2020
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16. Spatial distribution of exoplanet candidates based on Kepler and $Gaia$ data

Author: Maliuk, Andrii and Budaj, Jan
Subjects: Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Astrophysics of Galaxies, Astrophysics - Solar and Stellar Astrophysics
Abstract: The spatial distribution of exoplanets in the Galaxy is important for our understanding of planet formation and evolution. We aim to determine the spatial gradients of exoplanet occurrence in the Solar neighbourhood and in the vicinity of open clusters. We combined Kepler and Gaia DR2 data for this purpose, splitting the volume sampled by the Kepler mission into certain spatial bins. We determined an uncorrected and bias-corrected exoplanet frequency and metallicity for each bin. There is a clear drop in the uncorrected exoplanet frequency with distance for F-type stars, a decline with increasing distance along the Galactic longitude l=90 deg, and a drop with height above the Galactic plane. We find that the metallicity behaviour cannot be the reason for the drop of the exoplanet frequency around F stars with increasing distance. We argue that the above-mentioned gradients of uncorrected exoplanet frequency result from a single bias of undetected smaller planets around fainter stars. When we correct for observational biases, most of these gradients in exoplanet frequency become statistically insignificant. Only a slight decline of the planet occurrence with distance for F stars remains significant at the 3 sigma level. Apart from that, the spatial distribution of exoplanets in the Kepler field of view is compatible with a homogeneous one. At the same time, we do not find a significant change in the exoplanet frequency with increasing distance from open clusters. As a byproduct, we identified six exoplanet host star candidates that are members of open clusters. Four of them are in the NGC 6811 (KIC 9655005, KIC 9533489, Kepler-66, Kepler-67) and two belong to NGC 6866 (KIC 8396288, KIC 8331612). Two out of the six had already been known to be cluster members., Comment: 17 pages, 5 figures, accepted in A&A
Published: 2020
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17. Extrasolar enigmas: from disintegrating exoplanets to exoasteroids

Author: Budaj, Jan, Kabath, Petr, and Palle, Enric
Subjects: Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract: Thousands of transiting exoplanets have been discovered to date, thanks in great part to the {\em Kepler} space mission. As in all populations, and certainly in the case of exoplanets, one finds unique objects with distinct characteristics. Here we will describe the properties and behaviour of a small group of `disintegrating' exoplanets discovered over the last few years (KIC 12557548b, K2-22b, and others). They evaporate, lose mass unraveling their naked cores, produce spectacular dusty comet-like tails, and feature highly variable asymmetric transits. Apart from these exoplanets, there is observational evidence for even smaller `exo-'objects orbiting other stars: exoasteroids and exocomets. Most probably, such objects are also behind the mystery of Boyajian's star. Ongoing and upcoming space missions such as {\em TESS} and PLATO will hopefully discover more objects of this kind, and a new era of the exploration of small extrasolar systems bodies will be upon us., Comment: Accepted for publication in the book "Reviews in Frontiers of Modern Astrophysics: From Space Debris to Cosmology" (eds Kabath, Jones and Skarka; publisher Springer Nature) funded by the European Union Erasmus+ Strategic Partnership grant "Per Aspera Ad Astra Simul" 2017-1-CZ01-KA203-035562
Published: 2020
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18. HD 99458: First time ever Ap-type star as a $\delta$ Scuti pulsator in a short period eclipsing binary?

Author: Skarka, M., Kabáth, P., Paunzen, E., Fedurco, M., Budaj, J., Dupkala, D., Krtička, J., Hatzes, A., Pribulla, T., Parimucha, Š., Mikulášek, Z., Guenther, E., Sabotta, S., Blažek, M., Dvořáková, J., Hambálek, L., Klocová, T., Kollár, V., Kundra, E., Šlechta, M., and Vaňko, M.
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: We present the discovery of a unique object, a chemically peculiar Ap-type star showing $\delta$ Scuti pulsations which is bound in an eclipsing binary system with an orbital period shorter than 3 days. HD 99458 is, therefore, a complex astrophysical laboratory opening doors for studying various, often contradictory, physical phenomena at the same time. It is the first Ap star ever discovered in an eclipsing binary. The orbital period of 2.722 days is the second shortest among all known chemically peculiar (CP2) binary stars. Pulsations of $\delta$ Scuti type are also extremely rare among CP2 stars and no unambiguously proven candidate has been reported. HD 99458 was formerly thought to be a star hosting an exoplanet, but we definitely reject this hypothesis by using photometric observations from the K2 mission and new radial velocity measurements. The companion is a low-mass red dwarf star ($M_{2}=0.45(2)$ M$_{\odot}$) on an inclined orbit ($i=73.2(6)$ degrees) that shows only grazing eclipses. The rotation and orbital periods are synchronized, while the rotation and orbital axes are misaligned. HD 99458 is an interesting system deserving of more intense investigations., Comment: 8 pages, 4 figures, 4 tables, accepted in MNRAS
Published: 2019
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19. Diagnosing the Clumpy Protoplanetary Disk of the UXor Type Young Star GM Cephei

Author: Huang, P. C., Chen, W. P., Mugrauer, M., Bischoff, R., Budaj, J., Burkhonov, O., Ehgamberdiev, S., Errmann, R., Garai, Z., Hsiao, H. Y., Janulis, R., Jensen, E. L. N., Kiyota, S., Kuramoto, K., Lin, C. S., Lin, H. C., Liu, J. Z, Lux, O., Naito, H., Neuhäuser, R., Ohlert, J., Pakštienė, E., Pribulla, T., Qvam, J. K. T., Raetz, St., Sato, S., Schwartz, M., Semkov, E., Takagi, S., Wagner, D., Watanabe, M., and Zhang, Y.
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: UX Orionis stars (UXors) are Herbig Ae/Be or T Tauri stars exhibiting sporadic occultation of stellar light by circumstellar dust. GM\,Cephei is such a UXor in the young ($\sim4$~Myr) open cluster Trumpler\,37, showing prominent infrared excess, emission-line spectra, and flare activity. Our photometric monitoring (2008--2018) detects (1)~an $\sim$3.43~day period, likely arising from rotational modulation by surface starspots, (2)~sporadic brightening on time scales of days due to accretion, (3)~irregular minor flux drops due to circumstellar dust extinction, and (4)~major flux drops, each lasting for a couple of months with a recurrence time, though not exactly periodic, of about two years. The star experiences normal reddening by large grains, i.e., redder when dimmer, but exhibits an unusual "blueing" phenomenon in that the star turns blue near brightness minima. The maximum extinction during relatively short (lasting $\leq 50$~days) events, is proportional to the duration, a consequence of varying clump sizes. For longer events, the extinction is independent of duration, suggestive of a transverse string distribution of clumps. Polarization monitoring indicates an optical polarization varying $\sim3\%$--8$\%$, with the level anticorrelated with the slow brightness change. Temporal variation of the unpolarized and polarized light sets constraints on the size and orbital distance of the circumstellar clumps in the interplay with the young star and scattering envelope. These transiting clumps are edge-on manifestations of the ring- or spiral-like structures found recently in young stars with imaging in infrared of scattered light, or in submillimeter of thermalized dust emission., Comment: 20 pages, 9 figures
Published: 2019
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20. Physical properties of beta Lyr A and its opaque accretion disk

Author: Mourard, D., Broz, M., Nemravova, J., Harmanec, P., Budaj, J., Baron, F., Monnier, J., Schaefer, G., Schmitt, H., Tallon-Bosc, I., Armstrong, J., Baines, E., Bonneau, D., Bozic, H., Clausse, J. M., Farrington, C., Gies, D., Jurysek, J., Korcakova, D., McAlister, H., Meilland, A., Nardetto, N., Svoboad, P., Slechta, M., Wolf, M., and Zasche, P.
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: Mass exchange and mass loss in close binaries can significantly affect their evolution, but a complete self-consistent theory of these processes is still to be developed. Processes such as radiative shielding due to a~hot-spot region, or a~hydrodynamical interaction of different parts of the gas stream have been studied previously. In order to test the respective predictions, it is necessary to carry out detailed observations of binaries undergoing the largescale mass exchange, especially for those that are in the rapid transfer phase. \bla is an archetype of such a system, having a long and rich observational history. Our goal for this first study is to quantitatively estimate the geometry and physical properties of the optically thick components, namely the Roche-lobe filling mass-losing star, and the accretion disk surrounding the mass-gaining star of \blae. A series of continuum visible and NIR spectro-interferometric observations by the NPOI, CHARA/MIRC and VEGA instruments covering the whole orbit of \bla acquired during a~two-week campaign in 2013 were complemented with \ubvr\ photometric observations acquired during a three-year monitoring of the system. We included NUV and FUV observations from OAO~A-2, IUE, and Voyager satellites.
Published: 2018
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21. $\tau$ Ori and $\tau$ Lib: Two new massive heartbeat binaries

Author: Pigulski, Andrzej, Kaminska, Monika K., Kaminski, Krzysztof, Paunzen, Ernst, Budaj, Jan, Pribulla, Theodor, Torres, Pascal J., Stateva, Ivanka, Niemczura, Ewa, Skarka, Marek, Alicavus, Filiz Kahraman, Sekeras, Matej, van der Swaelmen, Mathieu, Vanko, Martin, Vanzi, Leonardo, Borisova, Ana, Helminiak, Krzysztof, Alicavus, Fahri, Dimitrov, Wojciech, Tokarek, Jakub, Derekas, Aliz, Fernandez, Daniela, Garai, Zoltan, Napetova, Mirela, Komzik, Richard, Merle, Thibault, Ratajczak, Milena, Richardson, Noel D., Team, Ritter Observing, Kambe, Eiji, and Ukita, Nobuharu
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: We report the discovery of two massive eccentric systems with BRITE data, $\tau$ Ori and $\tau$ Lib, showing heartbeat effects close to the periastron passage. $\tau$ Lib exhibits shallow eclipses that will soon vanish due to the apsidal motion in the system. In neither system, tidally excited oscillations were detected., Comment: 3 pages, 1 figure, to appear in the Proceedings of the 3rd BRITE Science Conference
Published: 2018

22. The First Post-Kepler Brightness Dips of KIC 8462852

Author: Boyajian, Tabetha S., Alonso, Roi, Ammerman, Alex, Armstrong, David, Ramos, A. Asensio, Barkaoui, K., Beatty, Thomas G., Benkhaldoun, Z., Benni, Paul, Bentley, Rory, Berdyugin, Andrei, Berdyugina, Svetlana, Bergeron, Serge, Bieryla, Allyson, Blain, Michaela G., Blanco, Alicia Capetillo, Bodman, Eva H. L., Boucher, Anne, Bradley, Mark, Brincat, Stephen M., Brink, Thomas G., Briol, John, Brown, David J. A., Budaj, J., Burdanov, A., Cale, B., Carbo, Miguel Aznar, Garcia, R. Castillo, Clark, Wendy J, Clayton, Geoffrey C., Clem, James L., Coker, Phillip H, Cook, Evan M., Copperwheat, Chris M., Curtis, J., Cutri, R. M., Cseh, B., Cynamon, C. H., Daniels, Alex J., Davenport, James R. A., Deeg, Hans J., De Lorenzo, Roberto, De Jaeger, Thomas, Desrosiers, Jean-Bruno, Dolan, John, Dowhos, D. J., Dubois, Franky, Durkee, R., Dvorak, Shawn, Easley, Lynn, Edwards, N., Ellis, Tyler G., Erdelyi, Emery, Ertel, Steve, Farfán, Rafael. G., Farihi, J., Filippenko, Alexei V., Foxell, Emma, Gandolfi, Davide, Garcia, Faustino, Giddens, F., Gillon, M., González-Carballo, Juan-Luis, González-Fernández, C., Hernández, J. I. González, Graham, Keith A., Greene, Kenton A., Gregorio, J., Hallakoun, Na'ama, Hanyecz, Ottó, Harp, G. R., Henry, Gregory W., Herrero, E., Hildbold, Caleb F., Hinzel, D., Holgado, G., Ignácz, Bernadett, Ivanov, Valentin D., Jehin, E., Jermak, Helen E., Johnston, Steve, Kafka, S., Kalup, Csilla, Kardasis, Emmanuel, Kaspi, Shai, Kennedy, Grant M., Kiefer, F., Kielty, C. L., Kessler, Dennis, Kiiskinen, H., Killestein, T. L., King, Ronald A., Kollar, V., Korhonen, H., Kotnik, C., Könyves-Tóth, Réka, Kriskovics, Levente, Krumm, Nathan, Krushinsky, Vadim, Kundra, E., Lachapelle, Francois-Rene, Lacourse, D., Lake, P., Lam, Kristine, Lamb, Gavin P., Lane, Dave, Lau, Marie Wingyee, Lewin, Pablo, Lintott, Chris, Lisse, Carey, Logie, Ludwig, Longeard, Nicolas, Villanueva, M. Lopez, Ludington, E. Whit, Mainzer, A., Malo, Lison, Maloney, Chris, Mann, A., Mantero, A., Marengo, Massimo, Marchant, Jon, González, M. J. Martinez, Masiero, Joseph R., Mauerhan, Jon C., Mccormac, James, Mcneely, Aaron, Meng, Huan Y. A., Miller, Mike, Molnar, Lawrence A., Morales, J. C., Morris, Brett M., Muterspaugh, Matthew W., Nespral, David, Nugent, C. R., Nugent, Katherine M., Odasso, A., O'keeffe, Derek, Oksanen, A., O'meara, John M., Ordasi, András, Osborn, Hugh, Ott, John J., Parks, J. R., Perez, Diego Rodriguez, Petriew, Vance, Pickard, R., Pál, András, Plavchan, P., Plaza, C. Westendorp, Pollacco, Don, Nuñez, F. Pozo, Pozuelos, F. J., Rau, Steve, Redfield, Seth, Relles, Howard, Ribas, I., Richards, Jon, Saario, Joonas L. O., Safron, Emily J., Sallai, J. Martin, Sárneczky, Krisztián, Schaefer, Bradley E., Schumer, Clea F., Schwartzendruber, Madison, Siegel, Michael H., Siemion, Andrew P. V., Simmons, Brooke D., Simon, Joshua D., Simón-Diaz, S., Sitko, Michael L., Socas-Navarro, Hector, Sódor, Á., Starkey, Donn, Steele, Iain A., Stone, Geoff, Street, R. A., Sullivan, Tricia, Suomela, J., Swift, J. J., Szabó, Gyula M., Szabó, Róbert, Szakáts, Róbert, Szalai, Tamás, Tanner, Angelle M., Toledo-Padrón, B., Tordai, Tamás, Triaud, Amaury H. M. J., Turner, Jake D., Ulowetz, Joseph H., Urbanik, Marian, Vanaverbeke, Siegfried, Vanderburg, Andrew, Vida, Krisztián, Vietje, Brad P., Vinkó, József, Von Braun, K., Waagen, Elizabeth O., Walsh, Dan, Watson, Christopher A., Weir, R. C., Wenzel, Klaus, Williamson, Michael W., Wright, Jason T., Wyatt, M. C., Zheng, Weikang, and Zsidi, Gabriella
Subjects: Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Earth and Planetary Astrophysics
Abstract: We present a photometric detection of the first brightness dips of the unique variable star KIC 8462852 since the end of the Kepler space mission in 2013 May. Our regular photometric surveillance started in October 2015, and a sequence of dipping began in 2017 May continuing on through the end of 2017, when the star was no longer visible from Earth. We distinguish four main 1-2.5% dips, named "Elsie," "Celeste," "Skara Brae," and "Angkor", which persist on timescales from several days to weeks. Our main results so far are: (i) there are no apparent changes of the stellar spectrum or polarization during the dips; (ii) the multiband photometry of the dips shows differential reddening favoring non-grey extinction. Therefore, our data are inconsistent with dip models that invoke optically thick material, but rather they are in-line with predictions for an occulter consisting primarily of ordinary dust, where much of the material must be optically thin with a size scale <<1um, and may also be consistent with models invoking variations intrinsic to the stellar photosphere. Notably, our data do not place constraints on the color of the longer-term "secular" dimming, which may be caused by independent processes, or probe different regimes of a single process., Comment: 19 pages, 8 figures, accepted for publication in ApJL
Published: 2018
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23. Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial.

Author: Ray, Kausik K, Colhoun, Helen M, Szarek, Michael, Baccara-Dinet, Marie, Bhatt, Deepak L, Bittner, Vera A, Budaj, Andrzej J, Diaz, Rafael, Goodman, Shaun G, Hanotin, Corinne, Harrington, Robert A, Jukema, J Wouter, Loizeau, Virginie, Lopes, Renato D, Moryusef, Angèle, Murin, Jan, Pordy, Robert, Ristic, Arsen D, Roe, Matthew T, Tuñón, José, White, Harvey D, Zeiher, Andreas M, Schwartz, Gregory G, and Steg, Philippe Gabriel
Abstract: After acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction in mean LDL cholesterol to 1·4-1·8 mmol/L with ezetimibe or statins reduces cardiovascular events in patients with an acute coronary syndrome and diabetes. However, the efficacy and safety of further reduction in LDL cholesterol with an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) after acute coronary syndrome is unknown. We aimed to explore this issue in a prespecified analysis of the ODYSSEY OUTCOMES trial of the PCSK9 inhibitor alirocumab, assessing its effects on cardiovascular outcomes by baseline glycaemic status, while also assessing its effects on glycaemic measures including risk of new-onset diabetes.ODYSSEY OUTCOMES was a randomised, double-blind, placebo-controlled trial, done at 1315 sites in 57 countries, that compared alirocumab with placebo in patients who had been admitted to hospital with an acute coronary syndrome (myocardial infarction or unstable angina) 1-12 months before randomisation and who had raised concentrations of atherogenic lipoproteins despite use of high-intensity statins. Patients were randomly assigned (1:1) to receive alirocumab or placebo every 2 weeks; randomisation was stratified by country and was done centrally with an interactive voice-response or web-response system. Alirocumab was titrated to target LDL cholesterol concentrations of 0·65-1·30 mmol/L. In this prespecified analysis, we investigated the effect of alirocumab on cardiovascular events by glycaemic status at baseline (diabetes, prediabetes, or normoglycaemia)-defined on the basis of patient history, review of medical records, or baseline HbA1c or fasting serum glucose-and risk of new-onset diabetes among those without diabetes at baseline. The primary endpoint was a composite of death from coronary heart disease, non-fatal myocardial infarction, fatal or non-fatal ischaemic stroke, or unstable angina requiring hospital admission. ODYSSEY OUTCOMES is registered with ClinicalTrials.gov, number NCT01663402.At study baseline, 5444 patients (28·8%) had diabetes, 8246 (43·6%) had prediabetes, and 5234 (27·7%) had normoglycaemia. There were no significant differences across glycaemic categories in median LDL cholesterol at baseline (2·20-2·28 mmol/L), after 4 months' treatment with alirocumab (0·80 mmol/L), or after 4 months' treatment with placebo (2·25-2·28 mmol/L). In the placebo group, the incidence of the primary endpoint over a median of 2·8 years was greater in patients with diabetes (16·4%) than in those with prediabetes (9·2%) or normoglycaemia (8·5%); hazard ratio (HR) for diabetes versus normoglycaemia 2·09 (95% CI 1·78-2·46, p
Published: 2019

24. On the nature of the candidate T-Tauri star V501 Aurigae

Author: Vaňko, M., Torres, G., Hambálek, L., Pribulla, T., Buchhave, L. A., Budaj, J., Dubovský, P., Garai, Z., Ginski, C., Grankin, K., Komžík, R., Krushevska, V., Kundra, E., Marka, C., Mugrauer, M., Neuhaeuser, R., Ohlert, J., Parimucha, Š., Perdelwitz, V., Raetz, St., and Shugarov, S. Yu.
Subjects: Astrophysics - Solar and Stellar Astrophysics
Abstract: We report new multi-colour photometry and high-resolution spectroscopic observations of the long-period variable V501 Aur, previously considered to be a weak-lined T-Tauri star belonging to the Taurus-Auriga star-forming region. The spectroscopic observations reveal that V501 Aur is a single-lined spectroscopic binary system with a 68.8-day orbital period, a slightly eccentric orbit (e ~ 0.03), and a systemic velocity discrepant from the mean of Taurus-Auriga. The photometry shows quasi-periodic variations on a different, ~55-day timescale that we attribute to rotational modulation by spots. No eclipses are seen. The visible object is a rapidly rotating (vsini ~ 25 km/s) early K star, which along with the rotation period implies it must be large (R > 26.3 Rsun), as suggested also by spectroscopic estimates indicating a low surface gravity. The parallax from the Gaia mission and other independent estimates imply a distance much greater than the Taurus-Auriga region, consistent with the giant interpretation. Taken together, this evidence together with a re-evaluation of the LiI~$\lambda$6707 and H$\alpha$ lines shows that V501 Aur is not a T-Tauri star, but is instead a field binary with a giant primary far behind the Taurus-Auriga star-forming region. The large mass function from the spectroscopic orbit and a comparison with stellar evolution models suggest the secondary may be an early-type main-sequence star., Comment: 13 pages, 7 figures. Accepted to MNRAS
Published: 2017
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25. 2024 ESC Guidelines for the management of chronic coronary syndromes: Developed by the task force for the management of chronic coronary syndromes of the European Society of Cardiology (ESC) Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS)

Author: Vrints, Christiaan, Andreotti, Felicita, Koskinas, Konstantinos C, Rossello, Xavier, Adamo, Marianna, Ainslie, James, Banning, Adrian Paul, Budaj, Andrzej, Buechel, Ronny R, Chiariello, Giovanni Alfonso, Chieffo, Alaide, Christodorescu, Ruxandra Maria, Deaton, Christi, Doenst, Torsten, Jones, Hywel W, Kunadian, Vijay, Mehilli, Julinda, Milojevic, Milan, Piek, Jan J, and Pugliese, Francesca
Subjects: HEART failure, SEX factors in disease, CHEST pain, POSITRON emission tomography computed tomography, MAGNETIC resonance imaging, MAJOR adverse cardiovascular events, MEDICAL care
Abstract: The document titled "2024 ESC Guidelines for the management of chronic coronary syndromes" provides comprehensive guidelines for the diagnosis and management of chronic coronary syndromes. It covers various topics such as initial management, diagnostic testing, medical therapy, revascularization options, and treatment for specific patient groups. The guidelines emphasize shared decision-making, patient education, and adherence to healthy lifestyle behaviors. It also highlights the importance of long-term follow-up and care, including strategies to improve medication adherence. These resources can be useful for library patrons conducting research on chronic coronary syndrome and seeking evidence-based guidance on its diagnosis and treatment. [Extracted from the article]
Published: 2024
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26. Mysterious eclipses in the light-curve of KIC8462852: a possible explanation

Author: Neslusan, L. and Budaj, J.
Subjects: Astrophysics - Earth and Planetary Astrophysics
Abstract: Apart from thousands of `regular' exoplanet candidates, Kepler satellite has discovered a few stars exhibiting peculiar eclipse-like events. They are most probably caused by disintegrating bodies transiting in front of the star. However, the nature of the bodies and obscuration events, such as those observed in KIC8462852, remain mysterious. A swarm of comets or artificial alien mega-structures have been proposed as an explanation for the latter object. We explore the possibility that such eclipses are caused by the dust clouds associated with massive parent bodies orbiting the host star. We assumed a massive object and a simple model of the dust cloud surrounding the object. Then, we used the numerical integration to simulate the evolution of the cloud, its parent body, and resulting light-curves as they orbit and transit the star. We found that it is possible to reproduce the basic features in the light-curve of KIC8462852 with only four objects enshrouded in dust clouds. The fact that they are all on similar orbits and that such models require only a handful of free parameters provides additional support for this hypothesis. This model provides an alternative to the comet scenario. With such physical models at hand, at present, there is no need to invoke alien mega-structures for an explanation of these light-curves., Comment: Accepted to A&A. Identical to v1 but with language correction
Published: 2016
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27. Impact of COVID‐19 pandemic on acute heart failure admissions and mortality: a multicentre study (COV‐HF‐SIRIO 6 study)

Author: Jacek Kubica, Małgorzata Ostrowska, Wioleta Stolarek, Michał Kasprzak, Klaudyna Grzelakowska, Jacek Kryś, Aldona Kubica, Piotr Adamski, Przemysław Podhajski, Eliano Pio Navarese, Edyta Anielska‐Michalak, Oliwia Brycht, Andrzej Curzytek, Aneta Dudek, Leszek Gromadziński, Paweł Grzelakowski, Leszek Kamiński, Andrzej Kleinrok, Marcin Kostkiewicz, Marek Koziński, Paweł Król, Tomasz Kulawik, Gleb Minczew, Marcin Mindykowski, Agnieszka Pawlak, Janusz Prokopczuk, Grzegorz Skonieczny, Bożena Sobkowicz, Sergiusz Sowiński, Sebastian Stankala, Paweł Szymański, Andrzej Wester, Przemysław Wilczewski, Stanisław Bartuś, Andrzej Budaj, Mariusz Gąsior, Marcin Gruchała, Jarosław Drożdż, Miłosz Jaguszewski, Piotr Jankowski, Jacek Legutko, Maciej Lesiak, Przemysław Leszek, Przemysław Mitkowski, Jadwiga Nessler, Anna Tomaszuk‐Kazberuk, Agnieszka Tycińska, Tomasz Zdrojewski, and Jarosław Kaźmierczak
Subjects: Heart failure, COVID‐19, In‐hospital mortality, Hospitalization, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Abstract Aims The coronavirus disease‐2019 (COVID‐19) pandemic has changed the landscape of medical care delivery worldwide. We aimed to assess the influence of COVID‐19 pandemic on hospital admissions and in‐hospital mortality rate in patients with acute heart failure (AHF) in a retrospective, multicentre study. Methods and results From 1 January 2019 to 31 December 2020, a total of 101 433 patients were hospitalized in 24 Cardiology Departments in Poland. The number of patients admitted due to AHF decreased by 23.4% from 9853 in 2019 to 7546 in 2020 (P
Published: 2022
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28. Biomarker Concentrations and Their Temporal Changes in Patients With Myocardial Infarction and Nonobstructive Compared With Obstructive Coronary Arteries: Results From the PLATO Trial

Author: Marcus Hjort, Kai M. Eggers, Tatevik Ghukasyan Lakic, Johan Lindbäck, Andrzej Budaj, Jan H. Cornel, Evangelos Giannitsis, Hugo A. Katus, Agneta Siegbahn, Robert F. Storey, Richard C. Becker, Lars Wallentin, and Bertil Lindahl
Subjects: biomarkers, myocardial infarction, myocardial infarction with nonobstructive coronary arteries, pathophysiology, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Background The pathobiology of myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA) is often uncertain. Investigating biomarker concentrations and their changes may offer novel pathophysiological insights. Methods and Results In this post hoc study of the PLATO (Platelet Inhibition and Patient Outcomes) trial, concentrations of hs‐cTnT (high‐sensitivity cardiac troponin T), NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide), hs‐CRP (high‐sensitivity C‐reactive protein), and GDF‐15 (growth differentiation factor 15) were measured in patients with MINOCA at baseline (n=554) and at 1‐month follow‐up (n=107). For comparisons, biomarkers were also measured in patients with MI with obstructive (stenosis ≥50%) coronary artery disease (baseline: n=11 106; follow‐up: n=2755]). Adjusted linear regression models were used to compare concentrations and their short‐ and long‐term changes. The adjusted geometric mean ratios (GMRs) in patients with MINOCA (median age, 61 years; 50.4% women) indicated lower hs‐cTnT (GMR, 0.77 [95% CI, 0.68–0.88]) but higher hs‐CRP (GMR, 1.21 [95% CI, 1.08–1.37]) and GDF‐15 concentrations (GMR, 1.06 [95% CI, 1.02–1.11]) at baseline compared with patients with MI with obstructive coronary artery disease, whereas NT‐proBNP concentrations were similar. Temporal decreases in hs‐cTnT, NT‐proBNP, and hs‐CRP concentrations until 1‐month follow‐up were more pronounced in patients with MINOCA. At follow‐up, patients with MINOCA had lower concentrations of hs‐cTnT (GMR, 0.71 [95% CI, 0.60–0.84]), NT‐proBNP (GMR, 0.45 [95% CI, 0.36–0.56]), and hs‐CRP (GMR, 0.68 [95% CI, 0.53–0.86]). One‐month GDF‐15 concentrations were similar between both groups with MI. Conclusions Biomarker concentrations suggest greater initial inflammatory activity, similar degree of myocardial dysfunction, and less pronounced myocardial injury during the acute phase of MINOCA compared with MI with obstructive coronary artery disease but also faster myocardial recovery. Registration URL: http://www.clinicaltrials.gov; Unique identifier: NCT00391872.
Published: 2023
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29. Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial

Author: Schwartz, Gregory G., Steg, Ph. Gabriel, Bhatt, Deepak L., Bittner, Vera A., Diaz, Rafael, Goodman, Shaun G., Harrington, Robert A., Jukema, J. Wouter, Szarek, Michael, White, Harvey D., Zeiher, Andreas M., Tricoci, Pierluigi, Roe, Matthew T., Mahaffey, Kenneth W., Edelberg, Jay M., Hanotin, Corinne, Lecorps, Guillaume, Moryusef, Angèle, Pordy, Robert, Sasiela, William J., Tamby, Jean-François, Aylward, Philip E., Drexel, Heinz, Sinnaeve, Peter, Dilic, Mirza, Lopes, Renato D., Gotcheva, Nina N., Prieto, Juan-Carlos, Yong, Huo, López-Jaramillo, Patricio, Pećin, Ivan, Reiner, Zeljko, Ostadal, Petr, Viigimaa, Margus, Nieminen, Markku S., Chumburidze, Vakhtang, Marx, Nikolaus, Danchin, Nicolas, Liberopoulos, Evangelos, Montenegro Valdovinos, Pablo Carlos, Tse, Hung-Fat, Kiss, Robert Gabor, Xavier, Denis, Zahger, Doron, Valgimigli, Marco, Kimura, Takeshi, Kim, Hyo Soo, Kim, Sang-Hyun, Erglis, Andrejs, Laucevicius, Aleksandras, Kedev, Sasko, Yusoff, Khalid, Ramos López, Gabriel Arturo, Alings, Marco, Halvorsen, Sigrun, Correa Flores, Roger M., Budaj, Andrzej, Morais, Joao, Dorobantu, Maria, Karpov, Yuri, Ristic, Arsen D., Chua, Terrance, Murin, Jan, Fras, Zlatko, Dalby, Anthony J., Tuñón, José, de Silva, H. Asita, Hagström, Emil, Landmesser, Ulf, Chiang, Chern-En, Sritara, Piyamitr, Guneri, Sema, Parkhomenko, Alexander, Ray, Kausik K., Moriarty, Patrick M., Vogel, Robert, Chaitman, Bernard, Kelsey, Sheryl F., Olsson, Anders G., Rouleau, Jean-Lucien, Simoons, Maarten L., Alexander, Karen, Meloni, Chiara, Rosenson, Robert, Sijbrands, Eric J.G., Alexander, John H., Armaganijan, Luciana, Bagai, Akshay, Bahit, Maria Cecilia, Brennan, J. Matthew, Clifton, Shaun, DeVore, Adam D., Deloatch, Shalonda, Dickey, Sheila, Dombrowski, Keith, Ducrocq, Grégory, Eapen, Zubin, Endsley, Patricia, Eppinger, Arleen, Harrison, Robert W., Hess, Connie Ng, Hlatky, Mark A., Jordan, Joseph Dedrick, Knowles, Joshua W., Kolls, Bradley J., Kong, David F., Leonardi, Sergio, Lillis, Linda, Maron, David J., Marcus, Jill, Mathews, Robin, Mehta, Rajendra H., Mentz, Robert J., Moreira, Humberto Graner, Patel, Chetan B., Bernardez-Pereira, Sabrina, Perkins, Lynn, Povsic, Thomas J., Puymirat, Etienne, Schuyler Jones, William, Shah, Bimal R., Sherwood, Matthew W., Stringfellow, Kenya, Sujjavanich, Darin, Toma, Mustafa, Trotter, Charlene, Van Diepen, Sean, Wilson, Matthew D., Yan, Andrew T., Schiavi, Lilia B., Garrido, Marcelo, Alvarisqueta, Andrés F., Sassone, Sonia A., Bordonava, Anselmo P., Alves De Lima, Alberto E., Schmidberg, Jorge M., Duronto, Ernesto A., Caruso, Orlando C., Novaretto, Leonardo P., Hominal, Miguel Angel, Montaña, Oscar R., Caccavo, Alberto, Gomez Vilamajo, Oscar A., Lorenzatti, Alberto J., Cartasegna, Luis R., Paterlini, Gustavo A., Mackinnon, Ignacio J., Caime, Guillermo D., Amuchastegui, Marcos, Salomone, Oscar, Codutti, Oscar R., Jure, Horacio O., Bono, Julio OE, Hrabar, Adrian D., Vallejos, Julio A., Ahuad Guerrero, Rodolfo A., Novoa, Federico, Patocchi, Cristian A., Zaidman, Cesar J., Giuliano, Maria E., Dran, Ricardo D., Vico, Marisa L., Carnero, Gabriela S., Guzman, Pablo N., Medrano Allende, Juan C., Garcia Brasca, Daniela F., Bustamante Labarta, Miguel H, Nani, Sebastian, Blumberg, Eduardo DS, Colombo, Hugo R, Liberman, Alberto, Fuentealba, Victorino, Luciardi, Hector L, Waisman, Gabriel D, Berli, Mario A, Garcia Duran, Ruben O, Cestari, Horacio G, Luquez, Hugo A, Giordano, Jorge A, Saavedra, Silvia S, Zapata, Gerardo, Costamagna, Osvaldo, Llois, Susana, Waites, Jonathon H, Collins, Nicholas, Soward, Allan, Hii, Chris LS, Shaw, James, Arstall, Margaret A, Horowitz, John, Ninio, Daniel, Rogers, James F, Colquhoun, David, Oqueli Flores, Romulo E, Roberts-Thomson, Philip, Raffel, Owen, Lehman, Sam J, Aroney, Constantine, Coverdale, Steven GM, Garrahy, Paul J, Starmer, Gregory, Sader, Mark, Carroll, Patrick A, Dick, Ronald, Zweiker, Robert, Hoppe, Uta, Huber, Kurt, Berger, Rudolf, Delle-Karth, Georg, Frey, Bernhard, Weidinger, Franz, Faes, Dirk, Hermans, Kurt, Pirenne, Bruno, Leone, Attilio, Hoffer, Etienne, Vrolix, Mathias CM, De Wolf, Luc, Wollaert, Bart, Castadot, Marc, Dujardin, Karl, Beauloye, Christophe, Vervoort, Geert, Striekwold, Harry, Convens, Carl, Roosen, John, Barbato, Emanuele, Claeys, Marc, Cools, Frank, Terzic, Ibrahim, Barakovic, Fahir, Midzic, Zlatko, Pojskic, Belma, Fazlibegovic, Emir, Kulić, Mehmed, Durak-Nalbantic, Azra, Vulic, Dusko, Muslibegovic, Adis, Goronja, Boris, Reis, Gilmar, Sousa, Luciano, Nicolau, Jose C, Giorgeto, Flavio E, Silva, Ricardo P, Nigro Maia, Lilia, Rech, Rafael, Rossi, Paulo RF, Cerqueira, Maria José AG, Duda, Norberto, Kalil, Renato, Kormann, Adrian, Abrantes, José Antonio M, Pimentel Filho, Pedro, Soggia, Ana Priscila, de Santos, Mayler ON, Neuenschwander, Fernando, Bodanese, Luiz C, Michalaros, Yorghos L, Eliaschewitz, Freddy G, Vidotti, Maria H, Leaes, Paulo E, Botelho, Roberto V, Kaiser, Sergio, Manenti, Euler Roberto Fernandes, Precoma, Dalton B, Moura Jorge, Jose C, de B Silva, Pedro G, Silveira, Jose A, Saporito, Wladmir, Marin-Neto, Jose A, Feitosa, Gilson S, Ritt, Luiz Eduardo F, de Souza, Juliana A, Costa, Fernando, Souza, Weimar KSB, Reis, Helder JL, Machado, Leandro, Ayoub, José Carlos Aidar, Todorov, Georgi V, Nikolov, Fedya P, Velcheva, Elena S, Tzekova, Maria L, Benov, Haralambi O, Petranov, Stanislav L, Tumbev, Haralin S, Shehova-Yankova, Nina S, Markov, Dimitar T, Raev, Dimitar H, Mollov, Mihail N, Kichukov, Kostadin N, Ilieva-Pandeva, Katya A, Ivanova, Raya, Gospodinov, Maryana, Mincheva, Valentina M, Lazov, Petar V, Dimov, Bojidar I, Senaratne, Manohara, Stone, James, Kornder, Jan, 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Published: 2019
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30. Prognostic value of galectin-3 and right ventricular function for long-term mortality in heart failure patients treated with cardiac resynchronization therapy

Author: Beata Zaborska, Ewa Pilichowska-Paszkiet, Ewa Makowska, Grażyna Sygitowicz, Tomasz Słomski, Michał Zaborski, and Andrzej Budaj
Subjects: Medicine, Science
Abstract: Abstract Recently, associations between the biomarker galectin-3 and numerous pathological processes involved in heart failure (HF) and right ventricular (RV) function have been observed. We aimed to assess the long-term prognostic ability of galectin-3 and RV function parameters for all-cause mortality in HF patients treated with cardiac resynchronization therapy (CRT). We prospectively studied 63 symptomatic HF patients with a left ventricular (LV) ejection fraction (EF) ≤ 35%. The median serum galectin-3 concentration was 13.4 ng/mL (IQR 11.05, 17.15). A detailed assessment of LV and RV geometry and function was performed with echocardiography. CRT defibrillator implantation was achieved in all patients without major complications. The follow-up lasted 5 years. In the multivariable Cox regression model, independent predictors for all-cause mortality were log baseline galectin-3 and baseline RV function expressed as tricuspid annular plane systolic excursion with HR 2.96 (p = 0.037) and HR 0.88 (p = 0.023), respectively. Analysis of subgroups defined by galectin-3 concentration and CRT response showed that patients with high baseline galectin-3 concentrations and a lack of response to CRT had a significantly lower probability of survival. In our patient cohort, the baseline galectin-3 concentration and RV function were independent predictors of long-term all-cause mortality in HFrEF patients following CRT implantation.
Published: 2021
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31. Apolipoprotein B, Residual Cardiovascular Risk After Acute Coronary Syndrome, and Effects of Alirocumab

Author: Hagström, Emil, Steg, P. Gabriel, Szarek, Michael, Bhatt, Deepak L., Bittner, Vera A., Danchin, Nicolas, Diaz, Rafael, Goodman, Shaun G., Harrington, Robert A., Jukema, J. Wouter, Liberopoulos, Evangelos, Marx, Nikolaus, McGinniss, Jennifer, Manvelian, Garen, Pordy, Robert, Scemama, Michel, White, Harvey D., Zeiher, Andreas M., Schwartz, Gregory G., Schwartz, Gregory G., Bhatt, Deepak L., Bittner, Vera A., Diaz, Rafael, Goodman, Shaun G., Harrington, Robert A., Jukema, J. Wouter, Szarek, Michael, White, Harvey D., Zeiher, Andreas M., Tricoci, Pierluigi, Roe, Matthew T., Mahaffey, Kenneth W., Edelberg, Jay M., Hanotin, Corinne, Lecorps, Guillaume, Moryusef, Angèle, Pordy, Robert, Sasiela, William J., Tamby, Jean-François, Diaz, Rafael, Aylward, Philip E, Drexel, Heinz, Sinnaeve, Peter, Dilic, Mirza, Lopes, Renato D., Gotcheva, Nina N, Goodman, Shaun G., Prieto, Juan-Carlos, Yong, Huo, López-Jaramillo, Patricio, Pećin, Ivan, Reiner, Zeljko, Ostadal, Petr, Poulsen, Steen Hvitfeldt, Viigimaa, Margus, Nieminen, Markku S, Danchin, Nicolas, Chumburidze, Vakhtang, Marx, Nikolaus, Liberopoulos, Evangelos, Carlos, Pablo, Valdovinos, Montenegro, Tse, Hung-Fat, Kiss, Robert Gabor, Xavier, Denis, Zahger, Doron, Valgimigli, Marco, Kimura, Takeshi, Kim, Hyo Soo, Kim, Sang-Hyun, Erglis, Andrejs, Laucevicius, Aleksandras, Kedev, Sasko, Yusoff, Khalid, Ramos López, Gabriel Arturo, Alings, Marco, White, Harvey D., Halvorsen, Sigrun, Correa Flores, Roger M, Sy, Rody G., Budaj, Andrzej, Morais, Joao, Dorobantu, Maria, Karpov, Yuri, Ristic, Arsen D., Chua, Terrance, Murin, Jan, Fras, Zlatko, Dalby, Anthony J, Tuñón, José, de Silva, H. 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Joachim, Völler, Heinz, Waltenberger, Johannes, Natour, Mohammed, Schmitt, Susanne, Müller-Wieland, Dirk, Steiner, Stephan, Heidenreich, Lothar, Offers, Elmar, Gremmler, Uwe, Killat, Holger, Rieker, Werner, Patsilinakos, Sotiris, Kartalis, Athanasios, Manolis, Athanassios, Sionis, Dimitrios, Chachalis, Geargios, Liberopoulos, Evangelos, Skoumas, Ioannis, Athyros, Vasilios, Vardas, Panagiotis, Parthenakis, Frangkiskos, Hahalis, Georgios, Lekakis, John, Hatzitolios, Apostolos, Fausto Ovando, Sergio R, Montenegro Valdovinos, Pablo Carlos, Arango Benecke, Juan L, Rodriguez De Leon, Edgar R, Yan, Bryan PY, Siu, David CW, Turi, Tibor, Merkely, Bela, Gabor Kiss, Robert, Ungi, Imre, Lupkovics, Geza, Nagy, Lajos, Katona, András, Édes, István, Müller, Gábor, Horvath, Iván, Kapin, Tibor, Szigeti, Zsolt, Faluközy, József, Kumbla, Mukund, Sandhu, Manjinder, Annam, Sharath, Reddy Proddutur, Naveen, Regella, Reddy, Premchand, Rajendra K, Mahajan, Ajaykumar, Pawar, Sudhir, Abhyanakar, Atul D, Kerkar, Prafulla, Govinda, Ravishankar A, Oomman, Abraham, Sinha, Dhurjati, Patil, Sachin N, Kahali, Dhiman, Sawhney, Jitendra, Joshi, Abhijeet B, Chaudhary, Sanjeev, Harkut, Pankaj, Guha, Santanu, Porwal, Sanjay, Jujjuru, Srimannarayana, Pothineni, Ramesh B, Monteiro, Minguel R, Khan, Aziz, Iyengar, Shamanna S, Grewal, Jasprakash Singh, Chopda, Manoj, Fulwani, Mahesh C, Patange, Dr. Aparna, Sachin, Patil, Chopra, Vijay K, Goyal, Naresh K, Shinde, Rituparna, Manakshe, Gajendra V, Patki, Nitin, Sethi, Sumeet, Munusamy, Vengatesh, Sunil Thanvi, Sunil Karnaand, Adhyapak, Srilakshmi, Patil, Chandrakant, Pandurangi, Ulhas, Mathur, Rishabh, Gupta, Jugal, Kalashetti, Suhas, Bhagwat, Ajit, Raghuraman, Bagirath, Kumar Yerra, Shiv, Bhansali, Prasant, Borse, Rohidas, Rahul, Patil, Das, Srihari, Kumar, Vinay, Abdullakutty, Jabir, Saathe, Shireesh, Palimkar, Priya, Abdullkutty, Jabir, Sathe, Shireesh, Atar, Shaul, Shechter, Michael, Mosseri, Morris, Arbel, Yaron, Ehud, Chorin, Ofer, Havakuk, Lotan, Chaim, Rosenschein, Uri, Katz, Amos, Henkin, Yaakov, Francis, Adi, Klutstein, Marc, Nikolsky, Eugenia, Zukermann, Robert, Turgeman, Yoav, Halabi, Majdi, Marmor, Alon, Kornowski, Ran, Jonas, Michael, Amir, Offer, Hasin, Yonathan, Rozenman, Yoseph, Fuchs, Shmuel, Zvi, Vered, Hussein, Osamah, Gavish, Dov, Vered, Zvi, Caraco, Yoseph, Elias, Mazen, Tov, Naveh, Wolfovitz, Efrat, Lishner, Michael, Elias, Nizar, Piovaccari, Giancarlo, Pellegrin, Annamaria De, Garbelotto, Raffaella, Guardigli, Gabriele, Marco, Valgimigli, Licciardello, Giovanni, Auguadro, Carla, Scalise, Filippo, Cuccia, Claudio, Salvioni, Alessandro, Musumeci, Giuseppe, Senni, Michelle, Calabrò, Paolo, Novo, Salvatore, Faggiano, Pompilio, Metra, Marco, De Cesare, Nicoletta B, Berti, Sergio, Puccioni, Enrico, Galvani, Marcello, Tespili, Maurizio, Piatti, Piermarco, Palvarini, Michela, Luca, Giuseppe De, Violini, Roberto, Leo, Alessandro De, Olivari, Zoran, Filardi, Pasquale Perrone, Ferratini, Maurizio, Racca, Vittorio, Dai, Kazuoki, Shimatani, Yuji, Kamiya, Haruo, Ando, Kenji, Takeda, Yoshihiro, Morino, Yoshihiro, Hata, Yoshiki, Kimura, Kazuo, Kishi, Koichi, Michishita, Ichiro, Uehara, Hiroki, Higashikata, Toshinori, Hirayama, Atsushi, Hirooka, Keiji, Doi, Yasuji, Sakagami, Satoru, Taguchi, Shuichi, Koike, Akihiro, Fujinaga, Hiroyuki, Koba, Shinji, Kozuma, Ken, Kawasaki, Tomohiro, Ono, Yujiro, Shimizu, Masatoshi, Katsuda, Yousuke, Wada, Atsuyuki, Shinke, Toshiro, Kimura, Takeshi, Ako, Junya, Fujii, Kenshi, Takahashi, Toshiyuki, Nakao, Koichi, Furukawa, Yutaka, Sugino, Hiroshi, Tamura, Ritsu, Mano, Toshiaki, Uematsu, Masaaki, Utsu, Noriaki, Ito, Kashima, Haraguchi, Takuya, Sato, Katsuhiko, Ueda, Yasunori, Nishibe, Akira, Fujimoto, Kazuteru, Masutani, Motomaru, Nishibe, Akira, Fujimoto, Kazuteru, Yoon, Jung Han, Kim, Sang-Hyun, Kim, Hack-Lyoung, Sik Park, Hun, Chae, In-Ho, Kim, Moo Hyun, Jeong, Myung Ho, Rha, Seungwoon, Kim, Chongjin, Kim, Hyo-Soo, Kim, Hae Young, Hong, Taekjong, Tahk, Seung-Jea, Kim, Youngkwon, Busmane, Arija, Pontaga, Natalija, Strelnieks, Aldis, Mintale, Iveta, Sime, Iveta, Petrulioniene, Zaneta, Kavaliauskiene, Roma, Jurgaitiene, Ruta, Sakalyte, Gintare, Slapikas, Rimvydas, Norkiene, Sigute, Misonis, Nerijus, Kibarskis, Aleksandras, Kubilius, Raimondas, Bojovski, Stojko, Kedev, Sasko, Lozance, Nensi, Kjovkaroski, Aleksandar, Doncovska, Snezana, Ong, Tiong Kiam, Kasim, Sazzli, Maskon, Oteh, Kandasamy, Balachandran, Yusoff, Khalid, Liew, Houng B, Wan Mohamed, Wan Mohd Izani, Castillo, Armando García, Ramos López, Gabriel Arturo, Calvillo, Jorge Carrillo, Campos, Pedro Fajardo, Núñez Fragoso, Juan Carlos, Bayram Llamas, Edmundo Alfredo, Alcocer Gamba, Marco Antonio, Madrigal, Jaime Carranza, González Salas, Luis Gerardo, Rosas, Enrique López, González Díaz, Belinda, Vázquez, Eduardo Salcido, Nacoud Ackar, Alfredo, Llamas Esperón, Guillermo Antonio, Martínez Sánchez, Carlos Rodolfo, De Leon, María Guerrero, Suarez Otero, Rodrigo, Salmón, Guillermo Fanghänel, Pérez Ríos, Jesús 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Sandy, Jain, Diwakar, Zainea, Mark, Bayron, Carlos, Karlsberg, Ronald, Dohad, Suhail, Lui, Henry, Keen, William, Westerhausen, Donald, Khurana, Sandeep, Agarwal, Himanshu, Birchem, Jessica, Penny, William, Chang, Mark, Murphy, Sherrill, Henry, John, Schifferdecker, Branislav, Gilbert, John M, Chalavarya, Gopal, Eaton, Charles, Schmedtje, John F, Christenson, Stuart, Dotani, Imran, Denham, Douglas, Macdonell, Alexander, Gibson, Paul, Rahman, Aref, Al Joundi, Tammam, Assi, Nizar, Conrad, Gary, Kotha, Purushotham, Love, Michael, Giesler, Gregory, Rubenstein, Howard, Gamil, Dawood, Akright, Laura, Krawczyk, Justine, Cobler, Joanne, Wells, Terry, Welker, James, Foster, Robert, Gilmore, Richard, Anderson, Jay, Jacoby, Douglas, Harris, Bill, Gardner, Geraldine, Dandillaya, Ramprasad, Vora, Kishor, Kostis, John, Hunter, John, Laxson, David, Ball, Eric, Anderson, Jay, Wells, Terry, Vora, Kishor, Ball, Eric, Welker, James, Lopes, Renato D., Egydio, Flavia, Kawakami, Anelise, Oliveira, Janaina, Goodman, Shaun G., Wozniak, Julianna, Matthews, Alexander, Ratky, Caroline, Valiris, Janine, Berdan, Lisa, Hepditch, Anita, Quintero, Kirby, Roe, Matthew T., Rorick, Tyrus, Westbrook, Melissa, Danchin, Nicolas, Bezault, Madeleine, Drouet, Elodie, Simon, Tabassome, White, Harvey D., Alsweiler, Caroline, Sinnaeve, Peter, Luyten, Anne, Aylward, Philip E, Butters, Julie, Griffith, Liddy, Shaw, Michelle, Hagström, Emil, Grunberg, Lena, Szarek, Michael, Islam, Shahidul, Brégeault, Marie-France, Bougon, Nathalie, Faustino, Douglas, Fontecave, Sylvie, Murphy, Judith, Tamby, Jean- Francois, Verrier, Melanie, Agnetti, Veronique, Andersen, Dorthe, Badreddine, Emmy, Bekkouche, Mhamed, Bouancheau, Cecile, Brigui, Imane, Brocklehurst, Maddy, Cianciarulo, Joseph, Devaul, Dawn, Domokos, Szilvia, Gache, Cecile, Gobillot, Caroline, Guillou, Severine, Healy, Jan, Heath, Megan, Jaiwal, Gayatri, Javierre, Carine, Labeirie, Julien, Monier, Myriam, Morales, Ulises, Mrabti, Asmaa, Mthombeni, Bicky, Okan, Betim, Smith, Lucile, Sheller, Jennifer, Sopena, Sebastien, Pellan, Valerie, Benbernou, Fadela, Bengrait, Nafissa, Lamoureux, Maud, Kralova, Katarina, Scemama, Michel, Bejuit, Raphael, Coulange, Anthony, Berthou, Christelle, Repincay, Jérôme, Lorenzato, Christelle, Etienne, Alexis, Gouet, Valerie, Lecorps, Guillaume, Loizeau, Virginie, Normand, Mickael, Ourliac, Anne, Rondel, Christelle, Adamo, Antony, Beltran, Pascale, Barraud, Pauline, Dubois-Gache, Helene, Halle, Benjamin, Metwally, Lamia, Mourgues, Maxime, Sotty, Marc, Vincendet, Marion, Cotruta, Raluca, Chengyue, Zhu, Fournie-Lloret, Dominique, Morrello, Christine, Perthuis, Aurelie, Picault, Patrick, Zobouyan, Isabelle, Colhoun, Helen M., Dempsey, Michael A., and McClanahan, Mark A.
Published: 2022
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32. Contemporary Management of Severe Symptomatic Aortic Stenosis

Author: Iung, Bernard, Bax, Jeroen, De Bonis, Michele, Delgado, Victoria, Haude, Michael, Hindricks, Gerhard, Maggioni, Aldo P., Pierard, Luc, Popescu, Bogdan A., Prendergast, Bernard, Price, Susanna, Rosenhek, Raphael, Ruschitzka, Frank, Vahanian, Alec, Wendler, Olaf, Windecker, Stephan, Mekhaldi, Souad, Lemaitre, Katell, Authier, Sébastien, Laroche, Cécile, Abdelhamid, Magdy, Apor, Astrid, Bajraktari, Gani, Beleslin, Branko, Bogachev-Prokophiev, Alexander, Demarco, Daniela Cassar, Pasquet, Agnes, Dogan, Sait Mesut, Erglis, Andrejs, Evangelista, Arturo, Goda, Artan, Ihlemann, Nikolaj, Ince, Huseyin, Katsaros, Andreas, Linhartova, Katerina, Mascherbauer, Julia, Mirrakhimov, Erkin, Mizariene, Vaida, Rahman-Haley, Shelley, Ribeiras, Regina, Samadov, Fuad, Saraste, Antti, Simkova, Iveta, Kostovska, Elizabeta Srbinovska, Tomkiewicz-Pajak, Lidia, Tribouilloy, Christophe, Zera, Eliverta, Metalla, Mimoza, Shirka, Ervina, Dado, Elona, Bica, Loreta, Aleksi, Jorida, Knuti, Gerti, Gjyli, Lidra, Pjeci, Rudina, Shuperka, Eritinka, Lleshi, Erviola, Rustemaj, Joana, Qordja, Marsjon, Gina, Mirald, Husi, Senada, Basic, Daniel, Steringer-Mascherbauer, Regina, Huber, Charlotte, Ebner, Christian, Sigmund, Elisabeth, Ploechl, Andrea, Sturmberger, Thomas, Eder, Veronica, Koppler, Tanja, Heger, Maria, Kammerlander, Andreas, Duca, Franz, Binder, Christina, Koschutnik, Matthias, Perschy, Leonard, Puskas, Lisa, Ho, Chen-Yu, Aliyev, Farid, Guluzada, Vugar, Imanov, Galib, Ibrahimov, Firdovsi, Abbasaliyev, Abbasali, Ahmedov, Tahir, Muslumova, Fargana, Babayev, Jamil, Rustamova, Yasmin, Jahangirov, Tofig, Samadov, Rauf, Museyibov, Muxtar, Isayev, Elnur, Musayev, Oktay, Xalilov, Shahin, Huseynov, Saleh, Yuzbashova, Madina, Zamanov, Vuqar, Mammadov, Vusal, Van Camp, Gery, Penicka, Martin, Batjoens, Hedwig, Debonnaire, Philippe, Dendooven, Daniel, Knecht, Sebastien, Duytschaever, Mattias, Vandekerckhove, Yves, Missault, Luc, Muyldermans, Luc, Tavernier, René, De Grande, Tineke, Coussement, Patrick, DeTroyer, Joyce, Derycker, Katrien, De Jaegher, Kelly, Bondue, Antoine, Beauloye, Christophe, Goffinet, Céline, Mirica, Daniela Corina, Eynden, Frédéric Vanden, Van de Borne, Philippe, Van Frachen, Béatrice, Vancraeynest, David, Vanoverschelde, Jean Louis, Pierard, Sophie, Malanca, Mihaela, Sinnaeve, Florence, Tahon, Séverine, De Clippel, Marie, Gayet, Frederic, Loiseau, Jacques, Van de Veire, Nico, Moerman, Veronique, Willems, Anne-Marie, Cosyns, Bernard, Droogmans, Steven, Motoc, Andreea, Kerkhove, Dirk, Plein, Daniele, Roosens, Bram, Weytjens, Caroline, Lancellotti, Patrizio, Dulgheru, Elena Raluca, Parenicova, Ilona, Bedanova, Helena, Tousek, Frantisek, Sindelarova, Stepanka, Canadyova, Julia, Taborsky, Milos, Ostransky, Jiri, Ivona simkova, Vicha, Marek, Jelinek, Libor, Opavska, Irena, Homza, Miroslav, Kvrayola, Miriam, Brat, Radim, Mrozek, Dan, Lichnerova, Eva, Docekalova, Iveta, Zarybnicka, Marta, Peskova, Marketa, Roucka, Patrik, Stastna, Vlasta, Vondrackova, Dagmar Jungwirtova, Hornig, Alfred, Niznansky, Matus, Branny, Marian, Vodzinska, Alexandra, Dorda, Miloslav, Snkouril, Libor, Kluz, Krystyna, Kypusova, Jana, Nezvalova, Radka, Olsen, Niels Thue, Ali, Hosam Hasan, Taha, Salma, Hassan, Mohamed, Afifi, Ahmed, Kabil, Hamza, Mady, Amr, Ebaid, Hany, Ahmed, Yasser, Nour, Mohammad, Talaat, Islam, Sayed, CairoMaiy El, Mostafa, Ahmad Elsayed, Sadek, CairoYasser, Eltobgi, CairoSherif, Bakhoum, Sameh, Doss, Ramy, Sheashea, Mahmoud, Elasry, Abd Allah, Fouad, Ahmed, Baraka, Mahmoud, Samir, Sameh, Roshdy, Alaa, AbdelRazek, Yasmin, Abd Rabou, Mostafa M., Abobakr, Ahmed, Moaaz, Moemen, Mokhtar, Mohamed, Ashry, Mohamed, Elkhashab, Khaled, Ghareeb, Haytham Soliman, Kamal, Mostafa, AbdelRazek, Gomaa, Farag, GizaNabil, Elbarbary, Giza:Ahmed, Wahib, Evette, Kazamel, Ghada, Kamal, Diaa, Tantawy, Mahmoud, Alansary, Adel, Yahia, Mohammed, Mahmoud, Raouf, El Banna, Tamer, Atef, Mohamed, Nasr, Gamela, Ahmed, Salah, El Hefny, Ehab E., Saifelyazal, Islam, El Ghany, Mostafa Abd, El Rahman El Hadary, Abd, Khairy, Ahmed, Lommi, Jyri, Laine, Mika, Kylmala, Minna, Kankanen, Katja, Turpeinen, Anu, Hartikainen, Juha, Kujanen, Lari, Airaksinen, Juhani, Vasankari, Tuija, Szymanski, Catherine, Bohbot, Yohann, Gun, Mesut, Rousseaux, Justine, Biere, Loic, Mateus, Victor, Audonnet, Martin, Rautureau, Jérémy, Cornet, Charles, Sorbets, Emmanuel, Mear, BourgesKarine, Issa, Adi, Jobic, Yannick, Le Ven, Florent, Pouliquen, Marie-Claire, Gilard, Martine, Ohanessian, Alice, Farhat, Ali, Vlase, Alina, Said, Fkhar, Lasgi, Caroline, Sanchez, Carlos, Breil, Romain, Peignon, Marc, Elkaim, Jean-Philippe, Jan-Blin, Virginie, BertrandM'Ban, Sylvain Ropars, Bardet, Hélène, Sawadogo, Samuel, Muschoot, Aurélie, Tchatchoua, Dieudonné, Elhadad, Simon, Maubert, Aline, Lazizi, Tahar, Ourghi, Kais, Bonnet, Philippe, Menager-Gangloff, Clarisse, Gafsi, Sofiene, Mansouri, Djidjiga, Aboyans, Victor, Magne, Julien, Martins, Elie, Karm, Sarah, Mohty, Dania, Briday, Guillaume, David, Amandine, Marechaux, Sylvestre, Le Goffic, Caroline, Binda, Camille, Menet, Aymeric, Delelis, Francois, Ringlé, Anne, Castel, Anne-Laure, Appert, Ludovic, Tristram, Domitille, Trouillet, Camille, Nacer, Yasmine, Ngoy, Lucas, Habib, MarseilleGilbert, Thuny, Franck, Haentjens, Julie, Cautela, Jennifer, Lavoute, Cécile, Robin, Floriane, Armangau, Pauline, Vergeylen, Ugo, Sanhadji, Khalil, Abdallah, Nessim Hamed, Kerzazi, Hassan, Perianu, Mariana, Plurien, François, Oueslati, Chaker, Debauchez, Mathieu, Monin, Jean-Luc, Konstantinos, Zannis, Berrebi, Alain, Dibie, Alain, Lansac, Emmanuel, Veugeois, Aurélie, Diakov, Christelle, Caussin, Christophe, Czitrom, Daniel, Salvi, Suzanna, Amabile, Nicolas, Dervanian, Patrice, Lejeune, Stéphanie, Bagdadi, Imane, Mokrane, Yemmi, Rouault, Gilles, Abalea, Jerome, Leledy, Marion, Horen, Patrice, Donal, Erwan, Bosseau, Christian, Paven, Elise, Galli, Elena, Collette, Edouard, Urien, Jean-Marie, Bridonneau, Valentin, Gervais, Renaud, Bauer, Fabrice, Chopra, Houzefa, Charbonnier, Arthur, Attias, David, Dahouathi, Nesrine, Khounlaboud, Moukda, Daudin, Magalie, Thebault, Christophe, Hamon, Cécile, Couffon, Philippe, Bellot, Catherine, Vomscheid, Maelle, Bernard, Anne, Dion, Fanny, Naudin, Djedjiga, Mouzouri, Mohammed, Rudelin, Mathilde, Berenfeld, Alain, Vanzwaelmen, Thibault, Alloui, Tarik, Radovikj, Marija Gjerakaroska, Jordanova, Slavica, Scholtz, Werner, Liberda-Knoke, Eva, Wiemer, Melanie, Mugge, Andreas, Nickenig, Georg, Sinning, Jan-Malte, Sedaghat, Alexander, Heintzen, Matthias, Ballof, Jan, Frenk, Daniel, Hambrecht, Rainer, Wienbergen, Harm, Seidel, Annemarie, Osteresch, Rico, Kramer, Kirsten, Ziemann, Janna, Schulze, Ramona, Fehske, Wolfgang, Eifler, Clarissa, Wafaisade, Bahram, Kuhn, Andreas, Fischer, Sören, Lichtenberg, Lutz, Brunold, Mareike, Simons, Judith, Balling, Doris, Buck, Thomas, Plicht, Bjoern, Schols, Wolfgang, Ebelt, Henning, Chamieh, Marwan, Anacker, Jelena, Rassaf, Tienush, Janosi, Alexander, Lind, Alexander, Lortz, Julia, Lüdike, Peter, Kahlert, Philipp, Rittger, Harald, Eichinger, Gabriele, Kuhls, Britta, Felix, Stephan B., Lehnert, Kristin, Pedersen, Ann-Louise, Dorr, Marcus, Empen, Klaus, Kaczmarek, Sabine, Busch, Mathias, Baly, Mohammed, Er, Fikret, Duman, Erkan, Gabriel, Linda, Weinbrenner, Christof, Bauersachs, Johann, Wider, Julian, Kempf, Tibor, Bohm, Michael, Schulze, Paul-Christian, Poerner, C. Tudor, Möbius-Winkler, Sven, Lenk, Karsten, Heitkamp, Kerstin, Franz, Marcus, Krauspe, Sabine, Schumacher, Burghard, Windmuller, Volker, Kurwitz, Sarah, Thiele, Holger, Kurz, Thomas, Meyer-Saraei, Roza, Akin, Ibrahim, Fastner, Christian, Lossnitzer, Dirk, Hoffmann, Ursula, Borggrefe, Martin, Baumann, Stefan, Kircher, Brigitte, Foellinger, Claudia, Dietz, Heike, Schieffer, Bernhard, Niroomand, Feraydoon, Mudra, Harald, Maier, Lars, Camboni, Daniele, Birner, Christoph, Debl, Kurt, Paulus, Michael, Seither, Benedikt, El Mokhtari, Nour Eddine, Oner, Alper, Caglayan, Evren, Sherif, Mohammed, Yucel, Seyrani, Custodis, Florian, Schwinger, Robert, Vorpahl, Marc, Seyfarth, Melchior, Nover, Ina, Koehler, Till, Christiani, Sarah, Sanchez, David Calvo, Schanze, Barbel, Sigusch, Holger, Salman, Athir, Hancock, Jane, Chambers, John, Demetrescue, Camelia, Prendergast, Claire, Dalby, Miles, Smith, Robert, Rogers, Paula, Riley, Cheryl, Tousoulis, Dimitris, Kanakakis, Ioannis, Spargias, Konstantinos, Lampropoulos, Konstantinos, Panagiotis, Tolis, Koutsoukis, Athanasios, Michalis, Lampros, Goudevenos, Ioannis, Bellos, Vasileios, Papafaklis, Michail, Lakkas, Lampros, Hahalis, George, Makris, Athanasios, Karvounis, Haralampos, Kamperidis, Vasileios, Ninios, Vlasis, Sachpekidis, Vasileios, Rouskas, Pavlos, Poulimenos, Leonidas, Charalampidis, Georgios, Hamodraka, Eftihia, Manolis, Athanasios, Kiss, Robert Gabor, Borsanyi, Tunde, Jarai, Zoltan, Zsary, Andras, Bartha, Elektra, Kosztin, Annamaria, Doronina, Alexandra, Kovacs, Attila, Imre, Barabas Janos, Chao, Chun, Benke, Kalman, Karoczkai, Istvan, Keltai, Kati, Förchécz, Zsolt, Pozsonyi, Zoltán, Jenei, Zsigmond, Patthy, Adam, Sallai, Laszlo, Majoros, Zsuzsanna, Pál, Tamás, Bencze, Jusztina, Sagi, Ildiko, Molnar, Andrea, Kurczina, Anita, Kolodzey, Gabor, Edes, Istvan, Szatmari, Valeria, Zajacz, Zsuzsanna, Cziraki, Attila, Nemeth, Adam, Faludi, Reka, Vegh, Laszlone, Jebelovszki, Eva, Lupkovics, Geza Karoly, Kovacs, Zsofia, Horvath, Andras, Berisha, Gezim, Ibrahimi, Pranvera, Percuku, Luan, Arapova, Rano, Laahunova, Elmira, Neronova, Kseniia, Zhakypova, Zarema, Naizabekova, Gulira, Muratova, Gulnazik, Sime, Iveta, Sorokins, Nikolajs, Kamzola, Ginta, Cgojeva-Sproge, Irina, Rancane, Gita, Valentinaviciene, Ramune, Rudiene, Laima, Raugaliene, Rasa, Bardzilauske, Aiste, Jonkaitiene, Regina, Petrauskaite, Jurate, Bieseviciene, Monika, Verseckaite, Raimonda, Zvirblyte, Ruta, Kalibatiene, Danute, Radauskaite, Greta, Janaviciute-Matuzeviciene, Gabija, Jancauskaite, Dovile, Balkute, Deimile, Maneikyte, Juste, Mileryte, Ingrida, Vaisvilaite, Monika, Gedvilaite, Lina, Biliukas, Mykolas, Karpaviciene, Vaiva, Xuereb, Robert George, Pllaha, Elton, Djaberi, Roxana, Komor, Klaudiusz, Gorgon-Komor, Agnieszka, Loranc, Beata, Myszor, Jaroslaw, Mizia-Stec, Katarzyna, Berger-Kucza, Adrianna, Mizia, Magdalena, Polak, Mateusz, Bogacki, Piotr, Podolec, Piotr, Komar, Monika, Sedziwy, Ewa, Sliwiak, Dorota, Sobien, Bartosz, Rog, Beata, Hlawaty, Marta, Gancarczyk, Urszula, Libiszewska, Natasza, Sorysz, Danuta, Gackowski, Andrzej, Cieply, Malgorzata, Misiuda, Agnieszka, Racibor, Franciszek, Nytko, Anna, Widenka, Kazimierz, Kolowca, Maciej, Bak, Janusz, Curzytek, Andrzej, Regulski, Mateusz, Kamela, Malgorzata, Wisniowski, Mateusz, Hryniewiecki, Tomasz, Szymanski, Piotr, Rozewicz, Monika, Grabowski, Maciej, Duchnowski, Piotr, Budaj, Andrzej, Zaborska, Beata, Pilichowska-Paskiet, Ewa, Sikora-Frac, Malgorzata, Slomski, Tomasz, Joao, Isabel, Cruz, Ines, Pereira, Hélder, Cale, Rita, Marques, Ana, Pereira, Ana Rita, Morais, Carlos, Freitas, Antonio, Roque, David, Antunes, Nuno, Pereira, Antonio Costeira, Vieira, Catarina, Salome, Nuno, Martins, Juliana, Campos, Isabel, Cardoso, Goncalo, Silva, Claudia, Oliveira, Afonso, Goncalves, Mariana, Martins, Rui, Quintal, Nuno, Mendes, Bruno, Silva, Joseline, Ferreira, Joao, Milner, James, Alves, Patricia, Marinho, Vera, Gago, Paula, Amado, Jose, Bispo, Joao, Bento, Dina, Machado, 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Calin, Andreea, Botezatu, Simona, Enache, Roxana, Rosca, Monica, Ciuperca, Daniela, Babalac, Evelyn, Beyer, Ruxandra, Cadis, Laura, Rancea, Raluca, Tomoaia, Raluca, Rosianu, Adela, Kovacs, Emese, Militaru, Constantin, Craciun, Alina, Mirea, Oana, Florescu, Mihaela, Grigorica, Lucica, Dragusin, Daniela, Nechita, Luiza, Marinescu, Mihai, Chiscaneanu, Teodor, Botezatu, Lucia, Corciova, Costela, Petris, Antoniu Octavian, Arsenescu-Georgescu, Catalina, Salaru, Delia, Alexandrescu, Dan Mihai, Plesoianu, Carmjen, Tanasa, Ana, Mitu, Ovidiu, Costache, Irina Iuliana, Tudorancea, Ionut, Usurelu, Catalin, Eminovici, Gabriela, Manitiu, Ioan, Stoia, Oana, Mitre, Adriana, Nistor, Dan-Octavian, Maier, Anca, Lupu, Silvia, Opris, Mihaela, Ionac, Adina, Popescu, Irina, Crisan, Simina, Mornos, Cristian, Goanta, Flavia, Gruescu, Liana, Voinescu, Oana, Petcu, Madalina, Cozlac, Ramona, Damrina, Elena, Khilova, Liliya, Ryazantseva, Irina, Kozmin, Dmitry, Kiseleva, Maria, Goncharova, Marina, Kitalaeva, Kamila, Demetskay, Victoria, Verevetinov, Artem, Fomenko, Mikhail, Skripkina, Elena, Tsoi, Viktor, Antipov, Georgii, Schneider, Yuri, Yazikov, Denis, Makarova, Marina, Cherkes, Aleksei, Ermakova, Natalya, Medvedev, Aleksandr, Sarosek, Anastasia, Isayan, Mikhail, Voronova, Tatyana, Kulumbegov, Oleg, Tuchina, Alina, Stefanov, Sergei, Klimova, Margarita, Smolyaninov, Konstantin, Dandarova, Zhargalma, Magamet, Victoriya, Spiropulos, Natalia, Boldyrev, Sergey, Barbukhatty, Kirill, Buyankov, Dmitrii, Yurin, Vladimir, Gross, Yuriy, Boronin, Maksim, Mikhaleva, Mariya, Shablovskaya, Mariya, Zotov, Alex, Borisov, Daniil, Tereshchenko, Vasily, Zubova, Ekaterina, Kuzmin, A., Tarasenko, Ivan, Gamzaev, Alishir, Borovkova, Natalya, Koroleva, Tatyana, Botova, Svetlana, Pochinka, Ilya, Dunaeva, Vera, Teplitskaya, Victoria, Semenova, Elena I., Korabel'Nikova, Olga V., Simonov, Denis S., Denisenko, Elena, Harina, Natalia, Yarohno, Natalia, Alekseeva, Svetlana, Abydenkova, Julia, Shabalkina, Lyubov, Mayorova, Olga, Tsechanovich, Valeriy, Medvedev, Igor, Lepilin, Michail, Nemchenko, PenzaEvgenii, Karnahin, Vadim, Safina, Vasilya, Slastin, Yaroslav, Gilfanova, Venera, Gorbunov, Roman, Jakubov, Ramis, Fazylova, Aigul, Poteev, Mansur, Vazetdinova, Laysan, Tarasova, Indira, Irgaliyev, Rishat, Moiseeva, Olga, Gordeev, Mikhail, Irtyuga, Olga, Moiseeva, Raisa, Ostanina, Nina, Zverev, Dmitry, Murtazalieva, Patimat, Kuznetsov, Dmitry, Skurativa, Mariya, Polyaeva, Larisa, Mihaiilov, Kirill, Obrenovic-Kircanski, Biljana, Putnik, Svetozar, Simic, Dragan, Petrovic, Milan, Nikolic, Natasa Markovic, Jovovic, Ljiljana, Ostric, Dimitra Kalimanovska, Brajovic, Milan, Manojlovic, Milica Dekleva, Novakovic, Vladimir, Zamaklar-Trifunovic, Danijela, Orbovic, Bojana, Petrovic, Olga, Boricic-Kostic, Marija, Andjelkovic, Kristina, Milanov, Marko, Despotovic-Nikolic, Maja, Budisavljevic, Sreten, Veljkovic, Sanja, Cvetinovic, Nataša, Lepojevic, Daniijela, Todorovic, Aleksandra, Nikolic, Aleksandra, Borzanovic, Branislava, Trkulja, Ljiljana, Tomic, Slobodan, Vukovic, Milan, Milosavljevic, Jelica, Milanovic, Mirjana, Stakic, Vladan, Cvetkovic, Aleksandra, Milutinovic, Suzana, Bozic, Olivera, Miladinovic, Miodrag, Nikolic, Zoran, Despotovic, Dinka, Jovanovic, Dimitrije, Stojsic-Milosavljevic, Anastazija, Ilic, Aleksandra, Sladojevic, Mirjana, Susak, Stamenko, Maletin, Srdjan, Pavlovic, Salvo, Kuzmanovic, Vladimir, Ivanovic, Nikola, Dejanovic, Jovana, Ruzicic, Dusan, Drajic, Dragana, Cvetanovic, Danijel, Mirkovic, Marija, Omoran, Jon, Margoczy, Roman, Sedminova, Katarina, Reptova, Adriana, Baranova, Eva, Valkovicova, Tatiana, Valocik, Gabriel, Kurecko, Marian, Vachalcova, Marianna, Kollarova, Alzbeta, Studencan, Martin, Alusik, Daniel, Kozlej, Marek, Macakova, Jana, Moral, Sergio, Cladellas, Merce, Luiso, Daniele, Calvo, Alicia, Palet, Jordi, Carballo, Juli, Tura, Gisela Teixido, Maldonado, Giuliana, Gutierrez, Laura, Gonzalez-Alujas, Teresa, Jose Fernando, Rodriguez Palomares, Villalva, Nicolas, Molina-Mora, Ma Jose, Paton, Ramon Rubio, Martinez Diaz, Juan Jose, Ruiz, Pablo Ramos, Valle, Alfonso, Rodriguez, Ana, Alania, Edgardo, Galcera, Emilio, Seller, Julia, Valenzuela, Gonzalo de la Morena, Espin, Daniel Saura, Garcia, Dolores Espinosa, Oliva Sandoval, Maria Jose, Gonzalez, Josefa, Navarro, Miguel Garcia, Perez-Martinez, Maria Teresa, Ortega Trujillo, Jose Ramon, Gallego, Irene Menduina, San Roman, Daniel, Perez Nogales, Eliu David, Medina, Olga, Montiel Quintero, Rodolfo Antonio, Bujanda Morun, Pablo Felipe, Perez, Marta Lopez, Huaripata, Jimmy Plasencia, Morales Gonzalez, Juan Jose, Nelson, Veronica Quevedo, Zamorano, Jose Luis, Gomez, Ariana Gonzalez, Fraile, Alfonso, Alberca, Maria Teresa, Martin, Joaquin Alonso, Fernandez-Golfin, Covadonga, Ramos, Javier, Jimenez, Sergio Hernandez, Mitroi, Cristina, Sanchez Fernandez, Pedro L., Diaz-Pelaez, Elena, Garde, Beatriz, Caballero, Luis, Garcia, Fermin Martinez, Cambronero, Francisco, Castro, Noelia, Castro, Antonio, De La Rosa, Alejandro, Gallego, Pastora, Mendez, Irene, Villegas, David Villagomez, Correa, Manuel Gonzalez, Calvo, Roman, Florian, Francisco, Paya, Rafael, Esteban, Esther, Buendia, Francisco, Cubillos, Andrés, Fernandez, Carmen, Cárdenas, Juan Pablo, Pérez-Boscá, José Leandro, Vano, Joan, Belchi, Joaquina, Iglesia-Carreno, Cristina, Iglesias, Francisco Calvo, Escudero-Gonzalez, Aida, Zapateria-Lucea, Sergio, Duarte, Juan Sterling, Perez-Davila, Lara, Cobas-Paz, Rafael, Besada-Montenegro, Rosario, Fontao-Romeo, Maribel, Lopez-Rodriguez, Elena, Paredes-Galan, Emilio, Caneiro-Queija, Berenice, Gonzalez, Alba Guitian, Bozkurt, Abdi, Demir, Serafettin, Unlu, Durmus, Cagliyan, Caglar Emre, Ikikardes, Muslum Firat, Tangalay, Mustafa, Kuloglu, Osman, Ozer, Necla, Canpolat, Ugur, Kemaloglu, Melek Didem, Demirtas, Abdullah Orhan, Akgün, Didar Elif, Avci, Eyup, Taylan, Gokay, Yilmaztepe, Mustafa Adem, Ucar, Fatih Mehmet, Altay, Servet, Gurdogan, Muhammet, Gudul, Naile Eris, Aktas, Mujdat, Buyuklu, Mutlu, Degirmenci, Husnu, Turan, Mehmet Salih, Mert, Kadir Ugur, Mert, Gurbet Ozge, Dural, Muhammet, Arslan, Sukru, Sayar, Nurten, Kanar, Batur, Sadic, Beste Ozben, Sahin, Ahmet Anil, Buyuk, Ahmet, Kilicarslan, Onur, Bostan, Cem, Yildirim, Tarik, Yildirim, Seda Elcim, Cosansu, Kahraman, Varim, Perihan, Ilguz, Ersin, Demirbag, Recep, Yesilay, Asuman, Cirit, Abdullah, Tusun, Eyyup, Erkus, Emre, Sayin, Muhammet Rasit, Kazaz, Zeynep, Kul, Selim, Karabag, Turgut, Kalayci, Belma, Eugène, Marc, and Bax, Jeroen J.
Published: 2021
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33. Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol

Author: Schwartz, Gregory G., Gabriel Steg, P.h., Bhatt, Deepak L., Bittner, Vera A., Diaz, Rafael, Goodman, Shaun G., Harrington, Robert A., Jukema, J. Wouter, Szarek, Michael, White, Harvey D., Zeiher, Andreas M., Tricoci, Pierluigi, Roe, Matthew T., Mahaffey, Kenneth W., Edelberg, Jay M., Hanotin, Corinne, Lecorps, Guillaume, Moryusef, Angèle, Pordy, Robert, Sasiela, William J., Tamby, Jean-François, Aylward, Philip E., Drexel, Heinz, Sinnaeve, Peter, Dilic, Mirza, Lopes, Renato D., Gotcheva, Nina N., Prieto, Juan-Carlos, Yong, Huo, López-Jaramillo, Patricio, Pećin, Ivan, Reiner, Zeljko, Ostadal, Petr, Poulsen, Steen Hvitfeldt, Viigimaa, Margus, Nieminen, Markku S., Danchin, Nicolas, Chumburidze, Vakhtang, Marx, Nikolaus, Liberopoulos, Evangelos, Montenegro Valdovinos, Pablo Carlos, Tse, Hung-Fat, Kiss, Robert Gabor, Xavier, Denis, Zahger, Doron, Valgimigli, Marco, Kimura, Takeshi, Kim, Hyo Soo, Kim, Sang-Hyun, Erglis, Andrejs, Laucevicius, Aleksandras, Kedev, Sasko, Yusoff, Khalid, Ramos López, Gabriel Arturo, Alings, Marco, Halvorsen, Sigrun, Correa Flores, Roger M., Sy, Rody G., Budaj, Andrzej, Morais, Joao, Dorobantu, Maria, Karpov, Yuri, Ristic, Arsen D., Chua, Terrance, Murin, Jan, Fras, Zlatko, Dalby, Anthony J., Tuñón, José, Asita de Silva, H., Hagström, Emil, Landmesser, Ulf, Müller, Christian, Chiang, Chern-En, Sritara, Piyamitr, Guneri, Sema, Parkhomenko, Alexander, Ray, Kausik K., Moriarty, Patrick M., Vogel, Robert, Chaitman, Bernard, Kelsey, Sheryl F., Olsson, Anders G., Rouleau, Jean-Lucien, Simoons, Maarten L., Alexander, Karen, Meloni, Chiara, Rosenson, Robert, Sijbrands, Eric J.G., Alexander, John H., Armaganijan, Luciana, Bagai, Akshay, Bahit, Maria Cecilia, Brennan, J. Matthew, Clifton, Shaun, DeVore, Adam D., Deloatch, Shalonda, Dickey, Sheila, Dombrowski, Keith, Ducrocq, Grégory, Eapen, Zubin, Endsley, Patricia, Eppinger, Arleen, Harrison, Robert W., Hess, Connie Ng, Hlatky, Mark A., Jordan, Joseph Dedrick, Knowles, Joshua W., Kolls, Bradley J., Kong, David F., Leonardi, Sergio, Lillis, Linda, Maron, David J., Marcus, Jill, Mathews, Robin, Mehta, Rajendra H., Mentz, Robert J., Moreira, Humberto Graner, Patel, Chetan B., Pereira, Sabrina Bernardez, Perkins, Lynn, Povsic, Thomas J., Puymirat, Etienne, Jones, William Schuyler, Shah, Bimal R., Sherwood, Matthew W., Stringfellow, Kenya, Sujjavanich, Darin, Toma, Mustafa, Trotter, Charlene, van Diepen, Sean F.P., Wilson, Matthew D., Tze-Kay Yan, Andrew, Schiavi, Lilia B., Garrido, Marcelo, Alvarisqueta, Andrés F., Sassone, Sonia A., Bordonava, Anselmo P., Alves De Lima, Alberto E., Schmidberg, Jorge M., Duronto, Ernesto A., Caruso, Orlando C., Novaretto, Leonardo P., Hominal, Miguel Angel, Montaña, Oscar R., Caccavo, Alberto, Gomez Vilamajo, Oscar A., Lorenzatti, Alberto J., Cartasegna, Luis R., Paterlini, Gustavo A., Mackinnon, Ignacio J., Caime, Guillermo D., Amuchastegui, Marcos, Salomone, Oscar, Codutti, Oscar R., Jure, Horacio O., Bono, Julio O.E., Hrabar, Adrian D., Vallejos, Julio A., Ahuad Guerrero, Rodolfo A., Novoa, Federico, Patocchi, Cristian A., Zaidman, Cesar J., Giuliano, Maria E., Dran, Ricardo D., Vico, Marisa L., Carnero, Gabriela S., Guzman, Pablo N., Medrano Allende, Juan C., Garcia Brasca, Daniela F., Bustamante Labarta, Miguel H., Nani, Sebastian, Blumberg, Eduardo D.S., Colombo, Hugo R., Liberman, Alberto, Fuentealba, Victorino, Luciardi, Hector L., Waisman, Gabriel D., Berli, Mario A., Garcia Duran, Ruben O., Cestari, Horacio G., Luquez, Hugo A., Giordano, Jorge A., Saavedra, Silvia S., Zapata, Gerardo, Costamagna, Osvaldo, Llois, Susana, Waites, Jonathon H., Collins, Nicholas, Soward, Allan, Hii, Chris L.S., Shaw, James, Arstall, Margaret A., Horowitz, John, Ninio, Daniel, Rogers, James F., Colquhoun, David, Oqueli Flores, Romulo E., Roberts-Thomson, Philip, Raffel, Owen, Lehman, Sam J., Aroney, Constantine, Coverdale, Steven G.M., Garrahy, Paul J., Starmer, Gregory, Sader, Mark, Carroll, Patrick A., Dick, Ronald, Zweiker, Robert, Hoppe, Uta, Huber, Kurt, Berger, Rudolf, Delle-Karth, Georg, Frey, Bernhard, Faes, Dirk, Hermans, Kurt, Pirenne, Bruno, Leone, Attilio, Hoffer, Etienne, Vrolix, Mathias C.M., De Wolf, Luc, Wollaert, Bart, Castadot, Marc, Dujardin, Karl, Beauloye, Christophe, Vervoort, Geert, Striekwold, Harry, Convens, Carl, Roosen, John, Barbato, Emanuele, Claeys, Marc, Cools, Frank, Terzic, Ibrahim, Barakovic, Fahir, Midzic, Zlatko, Pojskic, Belma, Fazlibegovic, Emir, Durak-Nalbantic, Azra, Kulić, Mehmed, Vulic, Dusko, Muslibegovic, Adis, Goronja, Boris, Reis, Gilmar, Sousa, Luciano, Nicolau, Jose C., Giorgeto, Flavio E., Silva, Ricardo P., Maia, Lilia Nigro, Rech, Rafael, Rossi, Paulo R.F., Cerqueira, Maria José A.G., Duda, Norberto, Kalil, Renato, Kormann, Adrian, Abrantes, José Antonio M., Filho, Pedro Pimentel, Soggia, Ana Priscila, de Santos, Mayler O.N., Neuenschwander, Fernando, Bodanese, Luiz C., Michalaros, Yorghos L., Eliaschewitz, Freddy G., Vidotti, Maria H., Leaes, Paulo E., Botelho, Roberto V., Kaiser, Sergio, Fernandes Manenti, Euler Roberto F., Precoma, Dalton B., Moura Jorge, Jose C., Silva, Pedro, Silveira, Jose A., Saporito, Wladmir, Marin Neto, Jose A., Feitosa, Gilson S., Ritt, Luiz Eduardo F., de Souza, Juliana A., Costa, Fernando, Souza, Weimar K.S.B., Reis, Helder J.L., Machado, Leandro, Aidar Ayoub, José Carlos, Todorov, Georgi V., Nikolov, Fedya P., Velcheva, Elena S., Tzekova, Maria L., Benov, Haralambi O., Petranov, Stanislav L., Tumbev, Haralin S., Shehova-Yankova, Nina S., Markov, Dimitar T., Raev, Dimitar H., Mollov, Mihail N., Kichukov, Kostadin N., Ilieva-Pandeva, Katya A., Ivanova, Raya, Gospodinov, Maryana, Mincheva, Valentina M., Lazov, Petar V., Dimov, Bojidar I., Senaratne, Manohara, Stone, James, Kornder, Jan, Pearce, Stephen, Dion, Danielle, Savard, Daniel, Pesant, Yves, Pandey, Amritanshu, Robinson, Simon, Gosselin, Gilbert, Vizel, Saul, Hoag, Gordon, Bourgeois, Ronald, Morisset, Anne, Sabbah, Eric, Sussex, Bruce, Kouz, Simon, MacDonald, Paul, Diaz, Ariel, Michaud, Nicolas, Fell, David, Leung, Raymond, Vuurmans, Tycho, Lai, Christopher, Nigro, Frank, Davies, Richard, Nogareda, Gustavo, Vijayaraghavan, Ram, Ducas, John, Lepage, Serge, Mehta, Shamir, Cha, James, Dupuis, Robert, Fong, Peter, Lutchmedial, Sohrab, Rodes-Cabau, Josep, Fadlallah, Hussein, Cleveland, David, Huynh, Thao, Bata, Iqbal, Hameed, Adnan, Pincetti, Cristian, Potthoff, Sergio, Prieto, Juan C., Acevedo, Monica, Aguirre, Arnoldo, Vejar, Margarita, Yañez, Mario, Araneda, Guillermo, Fernandez, Mauricio, Perez, Luis, Varleta, Paola, Florenzano, Fernando, Huidobro, Laura, Raffo, Carlos A., Olivares, Claudia, Nahuelpan, Leonardo, Montecinos, Humberto, Chen, Jiyan, Dong, Yugang, Huang, Weijian, Wang, Jianzhong, Huang, Shi'An, Yao, Zhuhua, Li, Xiang, Cui, Lan, Lin, Wenhua, Sun, Yuemin, Wang, Jingfeng, Li, Jianping, Zhang, Xuelian, Zhu, Hong, Chen, Dandan, Huang, Lan, Dong, Shaohong, Su, Guohai, Xu, Biao, Su, Xi, Cheng, Xiaoshu, Lin, Jinxiu, Zong, Wenxia, Li, Huanming, Feng, Yi, Xu, Dingli, Yang, Xinchun, Ke, Yuannan, Lin, Xuefeng, Zhang, Zheng, Zheng, Zeqi, Luo, Zhurong, Chen, Yundai, Ding, Chunhua, Zhong, Yi, Zheng, Yang, Li, Xiaodong, Peng, Daoquan, Zhao, Shuiping, Li, Ying, Liu, Xuebo, Wei, Meng, Liu, Shaowen, Yu, Yihua, Qu, Baiming, Jiang, Weihong, Zhou, Yujie, Zhao, Xingsheng, Yuan, Zuyi, Guo, Ying, Xu, Xiping, Shi, Xubo, Ge, Junbo, Fu, Guosheng, Bai, Feng, Fang, Weiyi, Shou, Xiling, Yang, Xiangjun, Wang, Jian'An, Xiang, Meixiang, Sun, Yingxian, Lu, Qinghua, Zhang, Ruiyan, Zhu, Jianhua, Xu, Yizhou, Fan, Zhongcai, Li, Tianchang, Wu, Chun, Jaramillo, Nicolas, Vallejo, Gregorio Sanchez, Luna Botia, Diana C., Lopez, Rodrigo Botero, Molina De Salazar, Dora I., Cadena Bonfanti, Alberto J., Aroca, Carlos Cotes, Higuera, Juan Diego, Blanquicett, Marco, Barrera Silva, Sandra I., Garcia Lozada, Henry J., Coronel Arroyo, Julian A., Accini Mendoza, Jose L., Fernandez Ruiz, Ricardo L., Quintero Ossa, Alvaro M., Manzur Jatin, Fernando G., Herazo, Aristides Sotomayor, Parada, Jeffrey Castellanos, Arambula, Rafael Suarez, Urina Triana, Miguel A., Fernandez Trujillo, Angela M., Strozzi, Maja, Car, Siniša, Jerić, Melita, Miličić, Davor, Benčić, Martina Lovrić, Pintarić, Hrvoje, Prvulović, Đeiti, Šikić, Jozica, Peršić, Viktor, Mileta, Dean, Štambuk, Kresimir, Babić, Zdravko, Tomulic, Vjekoslav, Lukenda, Josip, Mejic-Krstulovic, Stanka, Starcevic, Boris, Spinar, Jindrich, Horak, David, Velicka, Zdenek, Stasek, Josef, Alan, David, Machova, Vilma, Linhart, Ales, Novotny, Vojtech, Kaucak, Vladimir, Rokyta, Richard, Naplava, Robert, Coufal, Zdenek, Adamkova, Vera, Podpera, Ivo, Zizka, Jiri, Motovska, Zuzana, Marusincova, Ivana, Svab, Premysl, Heinc, Petr, Kuchar, Jiri, Povolny, Petr, Matuska, Jiri, Poulsen, Steen H., Raungaard, Bent, Clemmensen, Peter, Bang, Lia E., May, Ole, Bøttcher, Morten, Hove, Jens D., Frost, Lars, Gislason, Gunnar, Larsen, John, Johansen, Peter Betton, Hald, Flemming, Johansen, Peter, Jeppesen, Jørgen, Nielsen, Tonny, Kristensen, Kjeld S., Walichiewicz, Piotr Maria, Lomholdt, Jens D., Klausen, Ib C., Nielsen, Peter Kaiser, Davidsen, Flemming, Videbaek, Lars, Soots, Mai, Vahula, Veiko, Hedman, Anu, Soopõld, Üllar, Märtsin, Kaja, Jurgenson, Tiina, Kristjan, Arved, Huikuri, Heikki, Pierre Coste, Juhani Airaksinen, Ferrari, Emile, Morel, Olivier, Montalescot, Gilles, Machecourt, Jacques, Barone-Rochette, Gilles, Mansourati, Jacques, Cottin, Yves, Leclercq, Florence, Belhassane, Abdelkader, Delarche, Nicolas, Boccara, Franck, Paganelli, Franck, Clerc, Jérôme, Schiele, Francois, Aboyans, Victor, Probst, Vincent, Berland, Jacques, Lefèvre, Thierry, Citron, Bernard, Khintibidze, Irakli, Shaburishvili, Tamaz, Pagava, Zurab, Ghlonti, Ramaz, Lominadze, Zaza, Khabeishvili, George, Hemetsberger, Rayyan, Edward, Kemala, Rauch-Kröhnert, Ursula, Stratmann, Matthias, Appel, Karl-Friedrich, Schmidt, Ekkehard, Omran, Heyder, Stellbrink, Christoph, Dorsel, Thomas, Lianopoulos, Emmanouil, Vöhringer, Hans Friedrich, Marx, Roger, Zirlik, Andreas, Schellenberg, Detlev, Heitzer, Thomas, Laufs, Ulrich, Werner, Christian, Gielen, Stephan, Nuding, Sebastian, Winkelmann, Bernhard, Behrens, Steffen, Sydow, Karsten, Karakas, Mahir, Simonis, Gregor, Muenzel, Thomas, Werner, Nikos, Leggewie, Stefan, Böcker, Dirk, Braun-Dullaeus, Rüdiger, Toursarkissian, Nicole, Jeserich, Michael, Weißbrodt, Matthias, Schaeufele, Tim, Weil, Joachim, Völler, Heinz, Waltenberger, Johannes, Natour, Mohammed, Schmitt, Susanne, Müller-Wieland, Dirk, Steiner, Stephan, Heidenreich, Lothar, Offers, Elmar, Gremmler, Uwe, Killat, Holger, Rieker, Werner, Patsilinakos, Sotiris, Kartalis, Athanasios, Manolis, Athanassios, Sionis, Dimitrios, Chachalis, Geargios, Skoumas, Ioannis, Athyros, Vasilios, Vardas, Panagiotis, Parthenakis, Frangkiskos, Lekakis, John, Hatzitolios, Apostolos, Fausto Ovando, Sergio R., Arango Benecke, Juan L., Rodriguez De Leon, Edgar R., Yan, Bryan P.Y., Siu, David C.W., Turi, Tibor, Merkely, Bela, Ungi, Imre, Lupkovics, Geza, Nagy, Lajos, Katona, András, Édes, István, Müller, Gábor, Horvath, Iván, Kapin, Tibor, Szigeti, Zsolt, Faluközy, József, Kumbla, Mukund, Sandhu, Manjinder, Annam, Sharath, Proddutur, Naveen Reddy, Regella, Reddy, Premchand, Rajendra K., Mahajan, Ajaykumar, Pawar, Sudhir, Abhyanakar, Atul D., Kerkar, Prafulla, Govinda, Ravishankar A., Oomman, Abraham, Sinha, Dhurjati, Patil, Sachin N., Kahali, Dhiman, Sawhney, Jitendra, Joshi, Abhijeet B., Chaudhary, Sanjeev, Harkut, Pankaj, Guha, Santanu, Porwal, Sanjay, Jujjuru, Srimannarayana, Pothineni, Ramesh B., Monteiro, Minguel R., Khan, Aziz, Iyengar, Shamanna S., Grewal, Jasprakash Singh, Chopda, Manoj, Fulwani, Mahesh C., Patange, Aparna, Sachin, Patil, Chopra, Vijay K., Goyal, Naresh K., Shinde, Rituparna, Manakshe, Gajendra V., Patki, Nitin, Sethi, Sumeet, Munusamy, Vengatesh, Sunil Thanvi, Sunil Karnaand, Adhyapak, Srilakshmi, Patil, Chandrakant, Pandurangi, Ulhas, Mathur, Rishabh, Gupta, Jugal, Kalashetti, Suhas, Bhagwat, Ajit, Raghuraman, Bagirath, Yerra, Shiv Kumar, Bhansali, Prasant, Borse, Rohidas, Rahul, Patil, Das, Srihari, Kumar, Vinay, Abdullakutty, Jabir, Saathe, Shireesh, Palimkar, Priya, Abdullkutty, Jabir, Sathe, Shireesh, Atar, Shaul, Shechter, Michael, Mosseri, Morris, Arbel, Yaron, Ehud, Chorin, Ofer, Havakuk, Lotan, Chaim, Rosenschein, Uri, Katz, Amos, Henkin, Yaakov, Francis, Adi, Klutstein, Marc, Nikolsky, Eugenia, Zukermann, Robert, Turgeman, Yoav, Halabi, Majdi, Marmor, Alon, Kornowski, Ran, Jonas, Michael, Amir, Offer, Hasin, Yonathan, Rozenman, Yoseph, Fuchs, Shmuel, Zvi, Vered, Hussein, Osamah, Gavish, Dov, Vered, Zvi, Caraco, Yoseph, Elias, Mazen, Tov, Naveh, Wolfovitz, Efrat, Lishner, Michael, Elias, Nizar, Piovaccari, Giancarlo, De Pellegrin, Annamaria, Garbelotto, Raffaella, Guardigli, Gabriele, Marco, Valgimigli, Licciardello, Giovanni, Auguadro, Carla, Scalise, Filippo, Cuccia, Claudio, Salvioni, Alessandro, Musumeci, Giuseppe, Senni, Michelle, Calabrò, Paolo, Novo, Salvatore, Faggiano, Pompilio, Metra, Marco, De Cesare, Nicoletta B., Berti, Sergio, Cavallini, Claudio, Puccioni, Enrico, Galvani, Marcello, Tespili, Maurizio, Piatti, Piermarco, Palvarini, Michela, De Luca, Giuseppe, Violini, Roberto, De Leo, Alessandro, Olivari, Zoran, Filardi, Pasquale Perrone, Ferratini, Maurizio, Racca, Vittorio, Dai, Kazuoki, Shimatani, Yuji, Kamiya, Haruo, Ando, Kenji, Takeda, Yoshihiro, Morino, Yoshihiro, Hata, Yoshiki, Kimura, Kazuo, Kishi, Koichi, Michishita, Ichiro, Uehara, Hiroki, Higashikata, Toshinori, Hirayama, Atsushi, Hirooka, Keiji, Doi, Yasuji, Sakagami, Satoru, Taguchi, Shuichi, Koike, Akihiro, Fujinaga, Hiroyuki, Koba, Shinji, Kozuma, Ken, Kawasaki, Tomohiro, Ono, Yujiro, Shimizu, Masatoshi, Katsuda, Yousuke, Wada, Atsuyuki, Shinke, Toshiro, Ako, Junya, Fujii, Kenshi, Takahashi, Toshiyuki, Sakamoto, Tomohiro, Nakao, Koichi, Furukawa, Yutaka, Sugino, Hiroshi, Tamura, Ritsu, Mano, Toshiaki, Uematsu, Masaaki, Utsu, Noriaki, Ito, Kashima, Haraguchi, Takuya, Sato, Katsuhiko, Ueda, Yasunori, Nishibe, Akira, Fujimoto, Kazuteru, Masutani, Motomaru, Yoon, Jung Han, Kim, Hack-Lyoung, Park, Hun Sik, Chae, In-Ho, Kim, Moo Hyun, Jeong, Myung Ho, Rha, Seungwoon, Kim, Chongjin, Kim, Hae Young, Hong, Taekjong, Tahk, Seung-Jea, Kim, Youngkwon, Busmane, Arija, Pontaga, Natalija, Strelnieks, Aldis, Mintale, Iveta, Sime, Iveta, Petrulioniene, Zaneta, Kavaliauskiene, Roma, Jurgaitiene, Ruta, Sakalyte, Gintare, Slapikas, Rimvydas, Norkiene, Sigute, Misonis, Nerijus, Kibarskis, Aleksandras, Kubilius, Raimondas, Bojovski, Stojko, Lozance, Nensi, Kjovkaroski, Aleksandar, Doncovska, Snezana, Ong, Tiong Kiam, Kasim, Sazzli, Maskon, Oteh, Kandasamy, Balachandran, Liew, Houng B., Izani Wan Mohamed, Wan Mohd, Castillo, Armando García, Calvillo, Jorge Carrillo, Campos, Pedro Fajardo, Núñez Fragoso, Juan Carlos, Bayram Llamas, Edmundo Alfredo, Alcocer Gamba, Marco Antonio, Madrigal, Jaime Carranza, González Salas, Luis Gerardo, Rosas, Enrique López, González Díaz, Belinda, Salcido Vázquez, Eduardo, Nacoud Ackar, Alfredo, Antonio Llamas Esperón, Guillermo, Rodolfo Martínez Sánchez, Carlos, Guerrero De Leon, María, Suarez Otero, Rodrigo, Fanghänel Salmón, Guillermo, Pérez Ríos, Jesús Antonio, Garza Ruíz, José Angel, Breedveld, Robert W., Feenema-Aardema, Margriet, Borger-Van Der Burg, Alida, Hoogslag, Pieter A.M., Suryapranata, Harry, Oomen, Antonius, Van Haelst, Paulus, Feenema-Aradema, Margriet, Wiersma, Jacobijne J., Basart, Dirk, Van Der Wal, Ruud M.A., Zwart, Peter, Monraats, Pascalle, Van Kesteren, Henricus, Karalis, Ioannis, Jukema, Johan, Verdel, Gerardus J.E., Brueren, Bart R.G., Troquay, Roland PTh, Viergever, Eric P., Al-Windy, Nadea Y.Y., 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František, Gonsorcik, Jozef, Bugan, Viliam, Selecky, Juraj, Kamensky, Gabriel, Strbova, Jaroslava, Smik, Rudolf, Dukat, Andrej, Olexa, Peter, Žuran, Ivan, Poklukar, Janez, Šuligoj, Nataša Černič, Cevc, Matija, Cyster, Henry P., Ranjith, Naresh, Corbett, Clive, Bayat, Junaid, Makotoko, Ellen Makoali, du Toit Theron, Hendrik, Kapp, Ilse E., de V Basson, Matthys M., Lottering, Hanlie, Van Aswegen, Dina, Van Zyl, Louis J., Sebastian, Peter J., Pillay, Thayabran, Saaiman, Jan A., Commerford, Patrick J., Cassimjee, Soraya, Riaz, Garda, Ebrahim, Iftikhar O., Sarvan, Mahomed, Mynhardt, Joseph H., Reuter, Helmuth, Moodley, Rajendran, Vida, Manuel, Cequier Fillat, Angel R., Peris, Vicente Bodí, Jimenez, Francisco Fuentes, Marín, Francisco, Cruz Fernández, Jose M., Hidalgo Urbano, Rafael Jesus, Gil-Extremera, Blas, Toledo, Pablo, Diz, Fernando Worner, Garcia-Dorado, David, Iñiguez, Andres, Fernández, José Tuñón, Gonzalez-Juanatey, Jose R., Portales, Javier Fernandez, Murillo, Fernando Civeira, Pericas, Laia Matas, Zamorano, Jose Luis, De Mora Martin, Manuel, Cortada, Jordi Bruguera, Alonso Martin, Joaquin J., Serrano Antolin, Jose Maria, De Berrazueta Fernández, José R., Vázquez de Prada, José Antonio, Díaz Fernández, Jose Francisco, García Lledó, José Alberto, Sales, Juan Cosín, Rodriguez, Javier Botas, Tragant, Gabriel Gusi, Benedicto, Amparo, Gonzalez-Juanatey, Carlos, Potau, Mercedes Camprubí, Perez, Ignacio Plaza, De La Tassa, César Morís, Loma-Osorio Rincon, Pablo, Recena, Javier Balaguer, Escudier, Juan M., Payeras, Antonio Coca, Orcajo, Norberto Alonso, Valdivielso, Pedro, Constantine, Godwin, Haniffa, Ruvaiz, Tissera, Nirmali, Amarasekera, Stanley, Ponnamperuma, Chandrike, Fernando, Nimali, Fernando, Kaputella, Jayawardena, Jayanthimala, Wijeyasingam, Santharaj, Ranasinghe, Gotabhaya, Ekanayaka, Ruvan, Mendis, Sepalika, Senaratne, Vajira, Mayurathan, Gnanamoorthy, Rajapaksha, Ajantha, Sirisena, Thilak, Herath, Jagath I., Amarasena, Naomali, Berglund, Stefan, Rasmanis, Gundars, Vedin, Ola, Witt, Nils, Mourtzinis, Georgios, Nicol, Peter, Hansen, Ole, Romeo, Stefano, Jensen, Steen Agergaard, Torstensson, Ingemar, Ahremark, Ulf, Sundelin, Torbjörn, Moccetti, Tiziano, Mach, Francois, Binde, Ronald, Gämperli, Oliver, Tsai, Wei-Chuan, Ueng, Kwo-Chang, Lai, Wen-Ter, Liu, Ming-En, Hwang, Juey-Jen, Yin, Wei-Hsian, Hsieh, I-Chang, Hsieh, Ming-Jer, Lin, Wei Hsiang, Kuo, Jen-Yuan, Huang, Tsuei-Yuan, Fang, Chih-Yuan, Kaewsuwanna, Pinij, Soonfuang, Wasant, Jintapakorn, Woravut, Sukonthasarn, Apichard, Wongpraparut, Nattawut, Sastravaha, Krisada, Sansanayudh, Nakarin, Kehasukcharoen, Wirash, Piyayotai, Dilok, Chotnoparatpat, Paiboon, Camsari, Ahmet, Kultursay, Hakan, Mutlu, Bulent, Ersanli, Murat, Demirtas, Mustafa, Kirma, Cevat, Ural, Ertan, Koldas, Lale, Karpenko, Oleksandr, Prokhorov, Alexander, Vakaluyk, Ihor, Myshanych, Halyna, Reshotko, Dmytro, Batushkin, Valeriy, Rudenko, Leonid, Kovalskyi, Ihor, Kushnir, Mykola, Tseluyko, Vira, Mostovoy, Yuriy, Stanislavchuk, Mykola, Kyiak, Yulian, Karpenko, Yuriy, Malynovsky, Yaroslav, Klantsa, Andriy, Kutniy, Oles, Amosova, Ekaterina, Tashchuk, Viktor, Leshchuk, Oleh, Rishko, Mykola, Kopytsya, Mykola, Yagensky, Andriy, Vatutin, Mykola, Bagriy, Andriy, Barna, Olga M., Ushakov, Olexiy, Dzyak, Georgiy, Goloborodko, Borys, Rudenko, Anatolii, Zheleznyy, Volodymyr, Trevelyan, Jasper, Zaman, Azfar, Lee, Kaeng, Moriarty, Andrew, Aggarwal, Rajesh K., Clifford, Piers, Wong, Yuk-Ki, Iqbal, Syed M.R., Subkovas, Eduardas, Braganza, Denise, Sarkar, David, Storey, Robert, Griffiths, Huw, Mcclure, Sam, Muthusamy, Rangasamy, Smith, Simon, Kurian, John, Levy, Terry, Barr, Craig, Kadr, Honer, Gerber, Robert, Simaitis, Audrius, Soran, Handrean, Mathur, Anthony, Brodison, Adrian, Ayaz, Mohammad, Cheema, Muhammad, Oliver, Richard, Thackray, Simon, Mudawi, Telal, Rahman, Gohar, Sultan, Ayyaz, Reynolds, Timothy, Sharman, David, david Sprigings, Butler, Rob, Wilkinson, Peter, Lip, Gregory Y.H., Halcox, Julian, Gallagher, Sean, Ossei-Gerning, Nicholas, Vardi, Gil, Baldari, Duccio, Brabham, David, Treasure, Charles, II, Dahl, Charles, Palmer, Bruce, Wiseman, Alan, Khan, Abul, Puri, Sanjeev, Mohart, Ann Elizabeth, Ince, Carlos, Flores, Enrique, Wright, Scott, Cheng, Shi-Chi, Rosenberg, Michael, Rogers, William, Jr., Kosinski, Edward, Forgosh, Les, Waltman, Jonathan, Khan, Misal, Shoukfeh, Mohammad, Dagher, Georges, Cambier, Patrick, Lieber, Ira, Kumar, Priya, East, Cara, Krichmar, Perry, Hasan, Mian, White, Lindsey, Knickelbine, Thomas, Haldis, Thomas, Gillespie, Eve, Amidon, Thomas, Suh, David, Arif, Imran, Abdallah, Mouhamad, Akhter, Faiq, Carlson, Eric, D'Urso, Michael, El-Ahdab, Fadi, Nelson, William, Moriarty, Katie, Harris, Barry, Cohen, Steven, Carter, Luther, Doty, Daniel, Sabatino, Kenneth, Haddad, Tariq, Malik, Amir, Rao, Sunder, Mulkay, Angel, Jovin, Ion, Klancke, Kim, Malhotra, Vinay, Devarapalli, Sai K., Koren, Michael, Chandna, Harish, Dodds, George, III, Goraya, Tauqir, Bengston, James, Janik, Matthew, Moran, Joseph, Sumner, Andrew, Kobayashi, John, Davis, William, Yazdani, Shahram, Pasquini, John, Thakkar, Maitreya, Vedere, Amarnath, Leimbach, Wayne, Rider, James, fenton, Sarah, Singh, Narendra, Shah, Anil V., Janosik, Denise, Pepine, Carl, Berman, Brett, Gelormini, Joseph, Daniels, Christopher, Richard, Kerensky, Keating, Friederike, Kondo, Nicholas I., Shetty, Sanjay, Levite, Howard, Waider, Winfried, Takata, Theodore, Abu-Fadel, Mazen, Shah, Vipul, Aggarwal, Rahul, Izzo, Mark, Kumar, Anil, Hattler, Brack, Do, Rose, Link, Chad, Bortnick, Anna, Kinzfogl, George, III, Ghitis, Arnold, Larry, John, Teufel, Edward, Kuhlman, Peter, Mclaurin, Brent, Zhang, Wenwu, Thew, Stephen, Abbas, Jalal, White, Matthew, Islam, Othman, Subherwal, Sumeet, Ranadive, Nandkishore, Vakili, Babak, Gring, Christian, Henderson, David, Schuchard, Timothy, Farhat, Naim, Kline, Geoffrey, Mahal, Sharan, Whitaker, Jack, Speirs, Shawn, Andersen, Rolf, Daboul, Nizar, Horwitz, Phillip, Zahr, Firas, Ponce, George, Jafar, Zubair, Mcgarvey, Joseph, Jr., Panchal, Vipul, Voyce, Stephen, Blok, Thomas, Sheldon, William, Azizad, Masoud M., Schmalfuss, Carsten, Picone, Mark, Pederson, Robert, Herzog, William, Jr., Friedman, Keith, Lindsey, Jason, Nowins, Rosemary, Timothy, Eichenlaub, Leonard, Parilak, Lepor, Norman, El Shahawy, Mahfouz, Weintraub, Howard, Irimpen, Anand, Alonso, Alvaro, May, Wade, Christopher, Daniels, Galski, Thomas, Chu, Alan, Mody, Freny, Ramin, Ebrahimi, Hodes, Zachary, Rossi, Joseph, Rose, Gregory, Fairlamb, James, Lambert, Charles, Jr., Raisinghani, Ajit, Abbate, Antonio, Vetrovec, George, King, Marilyn, Carey, Charles, Gerber, Jaime, Younis, Liwa, Park, Hyeun, Vidovich, Mladen, Knutson, Thomas, Friedman, Dennis, Chaleff, Fred, Loussararian, Arthur, Rozeman, Phillip, Kimmelstiel, Carey, Kuvin, Jeffrey, Silver, Kevin, Foster, Malcolm, Tonnessen, Glen, Espinoza, Andrey, Amlani, Mohamadali, Wali, Andreas, Malozzi, Christopher, Jong, Geert T., Massey, Clara, Wattanakit, Keattiyoat, O'Donnell, Philip J., Singal, Dinesh, Jaffrani, Naseem, Banuru, Sridhar, Fisher, Daniel, Xenakis, Mark, Perlmutter, Neal, Bhagwat, Ravi, Strader, James, Jr., Blonder, Ronald, Akyea-Djamson, Ayim, Labroo, Ajay, Lee, Kwan, Marais, H. John, Claxton, Edmund, Jr., Weiss, Robert, Kathryn, Rohr, Berk, Martin, Rossi, Peter, Joshi, Parag, Khera, Amit, Khaira, Ajit S., Kumkumian, Greg, Lupovitch, Steven, Purow, Joshua, Welka, Stephen, Hoffman, David, Fischer, Stuart, Soroka, Eugene, Eagerton, Donald, Pancholy, Samir, Ray, Michael, Erenrich, Norman, Farrar, Michael, Pollock, Stewart, French, William J., Diamantis, Steve, Guy, Douglas, Gimple, Lawrence, Neustel, Mark, Schwartz, Steven, Pereira, Edward, Albert, Seals, Spriggs, Douglas, Strain, Janet, Mittal, Suneet, Vo, Anthony, Chane, Majed, Hall, Jason, Vijay, Nampalli, Lotun, Kapildeo, Lester, F. Martin, Nahhas, Ahed, Pope, Theodore, Nager, Paul, Vohra, Rakesh, Sharma, Mukesh, Bashir, Riyaz, Ahmed, Hinan, Berlowitz, Michael, Fishberg, Robert, Barrucco, Robert, Yang, Eric, Radin, Michael, Sporn, Daniel, Stapleton, Dwight, Eisenberg, Steven, Landzberg, Joel, Mcgough, Martin, Turk, Samir, Schwartz, Michael, Sundram, P. Sandy, Jain, Diwakar, Zainea, Mark, Bayron, Carlos, Karlsberg, Ronald, Dohad, Suhail, Lui, Henry, Keen, William, Westerhausen, Donald, Jr., Khurana, Sandeep, Agarwal, Himanshu, Birchem, Jessica, Penny, William, Jr., Chang, Mark, Murphy, Sherrill, Henry, John, Schifferdecker ;John M Gilbert, Branislav, Chalavarya, Gopal, Eaton, Charles, Schmedtje, John F., Jr., Christenson, Stuart, Dotani, Imran, Denham, Douglas, Macdonell, Alexander, Gibson, Paul, Rahman, Aref, Al Joundi, Tammam, Assi, Nizar, Conrad, Gary, Kotha, Purushotham, Love, Michael, Giesler, Gregory, Rubenstein, Howard, Gamil, Dawood, Akright, Laura, Krawczyk, Justine, Cobler, Joanne, Wells, Terry, Welker, James, Foster, Robert, Gilmore, Richard, Anderson, Jay, Jacoby, Douglas, Harris, Bill, Gardner, Geraldine, Dandillaya, Ramprasad, Vora, Kishor, Kostis, John, Hunter, John, Laxson, David, Ball, Eric, Egydio, Flavia, Kawakami, Anelise, Oliveira, Janaina, Wozniak, Julianna, Matthews, Alexander, Ratky, Caroline, Valiris, Janine, Berdan, Lisa, Hepditch, Anita, Quintero, Kirby, Rorick, Tyrus, Westbrook, Melissa, Pascual, Andrea, Rovito, Carla, Bezault, Madeleine, Drouet, Elodie, Simon, Tabassome, Alsweiler, Caroline, Luyten, Anne, Butters, Julie, Griffith, Liddy, Shaw, Michelle, Grunberg, Lena, Islam, Shahidul, Brégeault, Marie-France, Bougon, Nathalie, Faustino, Douglas, Fontecave, Sylvie, Murphy, Judith, Verrier, Melanie, Veronique Agnetti, Andersen, Dorthe, Badreddine, Emmy, Bekkouche, Mhamed, Bouancheau, Cecile, Brigui, Imane, Brocklehurst, Maddy, Cianciarulo, Joseph, Devaul, Dawn, Domokos, Szilvia, Gache, Cecile, Gobillot, Caroline, Guillou, Severine, Healy, Jan, Heath, Megan, Jaiwal, Gayatri, Javierre, Carine, Labeirie, Julien, Monier, Myriam, Morales, Ulises, Mrabti, Asmaa, Mthombeni, Bicky, Okan, Betim, Smith, Lucile, Sheller, Jennifer, Sopena, Sebastien, Pellan, Valerie, Benbernou, Fadela, Bengrait, Nafissa, Lamoureux, Maud, Kralova, Katarina, Scemama, Michel, Bejuit, Raphael, Coulange, Anthony, Berthou, Christelle, Repincay, Jérôme, Lorenzato, Christelle, Etienne, Alexis, Gouet, Valerie, Loizeau, Virginie, Normand, Mickael, Ourliac, Anne, Rondel, Christelle, Adamo, Antony, Beltran, Pascale, Barraud, Pauline, Dubois-Gache, Helene, Halle, Benjamin, Metwally, Lamia, Mourgues, Maxime, Sotty, Marc, Vincendet, Marion, Cotruta, Raluca, Chengyue, Zhu, Fournie-Lloret, Dominique, Morrello, Christine, Perthuis, Aurelie, Picault, Patrick, Zobouyan, Isabelle, Colhoun, Helen M., Dempsey, Michael A., McClanahan, Mark A., Manvelian, Garen, Sinnaeve, Peter R., and Gabriel Steg, Ph
Published: 2021
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34. The Role of Galectin-3 in Heart Failure—The Diagnostic, Prognostic and Therapeutic Potential—Where Do We Stand?

Author: Beata Zaborska, Małgorzata Sikora-Frąc, Krzysztof Smarż, Ewa Pilichowska-Paszkiet, Andrzej Budaj, Dariusz Sitkiewicz, and Grażyna Sygitowicz
Subjects: galectin-3, heart failure, atrial fibrillation, fibrosis, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract: Heart failure (HF) is a clinical syndrome with high morbidity and mortality, and its prevalence is rapidly increasing. Galectin-3 (Gal-3) is an important factor in the pathophysiology of HF, mainly due to its role in cardiac fibrosis, inflammation, and ventricular remodeling. Fibrosis is a hallmark of cardiac remodeling, HF, and atrial fibrillation development. This review aims to explore the involvement of Gal-3 in HF and its role in the pathogenesis and clinical diagnostic and prognostic significance. We report data on Gal-3 structure and molecular mechanisms of biological function crucial for HF development. Over the last decade, numerous studies have shown an association between echocardiographic and CMR biomarkers in HF and Gal-3 serum concentration. We discuss facts and concerns about Gal-3’s utility in acute and chronic HF with preserved and reduced ejection fraction for diagnosis, prognosis, and risk stratification. Finally, we present attempts to use Gal-3 as a therapeutic target in HF.
Published: 2023
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35. Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice

Author: Stanisław Tubek, Wiktor Kuliczkowski, Mariusz Gąsior, Marek Gierlotka, Jacek Kubica, Andrzej Budaj, Adam Witkowski, Krzysztof Reczuch, and Piotr Ponikowski
Subjects: guidelines, antiplatelet treatment, st elevation myocardial infarction, non-st elevation myocardial infarction, Medicine
Abstract: Acute coronary syndrome is a factor for poor prognosis and recurrent cardiovascular events. Adequate antiplatelet therapy is crucial in patients with the acute coronary syndrome for risk reduction. Such treatment is well described in four documents issued by the European Society of Cardiology, which precisely illustrate the use of antiplatelets in the settings of ST-elevated and non-ST elevated myocardial infarction. Despite its unquestioned role in the treatment of acute coronary syndrome, recent real-world-data from Polish registries reveal poor adherence to the guidelines-recommended antiplatelet treatment in Poland. Thus, we present here a comprehensive review of the use of antiplatelets in the settings of the acute coronary syndrome. Each phase of the treatment, i.e. pre-hospital, in-hospital and post-hospital, is discussed separately for a better understanding of the decision-making process at each step. We also present unpublished data from Polish registries (e.g. PL-ACS 2019, National Registry of Procedures of Invasive Cardiology, RECEPTOmetrPEX panel) regarding adherence to the guidelines-recommended treatment in Poland, thus highlighting the points of care which should be immediately improved. It has to be stressed here that careful assessment of ischaemic and bleeding risk has to be performed in each patient with acute coronary syndrome individually and repeated at successive phases of the treatment. Only such an approach allows for appropriate antiplatelet therapy tailoring.
Published: 2021
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36. Temporal biomarker concentration patterns during the early course of acute coronary syndrome

Author: Eggers, Kai M., Batra, Gorav, Lindahl, Bertil, Lakic, Tatevik, Lindbäck, Johan, Budaj, Andrzej, Cornel, Jan H., Giannitsis, Evangelos, Katus, Hugo A., Storey, Robert F., Becker, Richard C., Siegbahn, Agneta, Wallentin, Lars, Eggers, Kai M., Batra, Gorav, Lindahl, Bertil, Lakic, Tatevik, Lindbäck, Johan, Budaj, Andrzej, Cornel, Jan H., Giannitsis, Evangelos, Katus, Hugo A., Storey, Robert F., Becker, Richard C., Siegbahn, Agneta, and Wallentin, Lars
Abstract: Objectives: Biomarker concentrations and their changes during acute coronary syndrome (ACS) provide clinically useful information on pathophysiological processes, e.g. myocardial necrosis, hemodynamic stress and inflammation. However, current evidence on temporal biomarker patterns early during ACS is limited, and studies investigating multiple biomarkers are lacking. Methods: We measured concentrations of high-sensitivity cardiac troponin T (hs-cTnT) and I (hs-cTnI), NT-terminal pro-B-type natriuretic peptide, C-reactive protein, and growth-differentiation factor-15 (GDF-15) in plasma samples obtained at randomization in ACS patients from the PLATelet inhibition and patient Outcomes (PLATO) trial. Linear regressions with interaction analyses were used to investigate the associations of biomarker concentrations with the time from symptom onset and to model temporal biomarker concentration patterns. Results: The study population consisted of 16,944 patients (median age 62 years; 71.3 % males) with 6,853 (40.3 %) having ST-elevation myocardial infarction (STEMI) and 10,141 (59.7 %) having non-ST-elevation ACS (NSTE-ACS). Concentrations of all biomarkers were associated with time from symptom onset (pinteraction<0.001), apart for GDF-15 (pinteraction=0.092). Concentration increases were more pronounced in STEMI compared to NSTE-ACS. Temporal biomarker patterns for hs-cTnT and hs-cTnI were different depending on sex whereas biomarker patterns for the other biomarkers were similar in cohorts defined by age and sex. Conclusions: Temporal concentration patterns differ for various biomarkers early during ACS, reflecting the variability in the activation and duration of different pathophysiological processes, and the amount of injured myocardium. Our data emphasize that the time elapsed from symptom onset should be considered for the interpretation of biomarker results in ACS.
Published: 2024
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37. Abstract 10470: Projected Lifetime Benefits of Alirocumab in Patients After Acute Coronary Syndrome

Author: Budaj, Andrzej, Elbez, Yedid, Schwartz, Gregory G, Bhatt, Deepak L, Bittner, Vera A, Chua, Terrance Sing Jin, Diaz, Rafael, Goodman, Shaun G, Harrington, Robert A, Jukema, J Wouter, Kedev, Sasko, Laucevicius, Alexander, MORAIS, JOAO, MURIN, Jan, Parkhomenko, Alexander, Pordy, Robert, Scemama, Michel, Szarek, Michael, White, Harvey D, and Steg, Philippe G
Published: 2022
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38. Ground-based transit observations of the HAT-P-18, HAT-P-19, HAT-P-27/WASP-40 and WASP-21 systems

Author: Seeliger, M., Kitze, M., Errmann, R., Richter, S., Ohlert, J. M., Chen, W. P., Guo, J. K., Göğüş, E., Güver, T., Aydın, B., Mottola, S., Hellmich, S., Fernandez, M., Aceituno, F. J., Dimitrov, D., Kjurkchieva, D., Jensen, E., Cohen, D., Kundra, E., Pribulla, T., Vaňko, M., Budaj, J., Mallonn, M., Wu, Z. Y., Zhou, X., Raetz, St., Adam, C., Schmidt, T. O. B., Ide, A., Mugrauer, M., Marschall, L., Hackstein, M., Chini, R., Haas, M., Ak, T., Güzel, E., Özdönmez, A., Ginski, C., Marka, C., Schmidt, J. G., Dincel, B., Werner, K., Dathe, A., Greif, J., Wolf, V., Buder, S., Pannicke, A., Puchalski, D., and Neuhäuser, R.
Subjects: Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract: As part of our ongoing effort to investigate transit timing variations (TTVs) of known exoplanets, we monitored transits of the four exoplanets HAT-P-18b, HAT-P-19b, HAT-P-27b/WASP-40b and WASP-21b. All of them are suspected to show TTVs due to the known properties of their host systems based on the respective discovery papers. During the past three years 46 transit observations were carried out, mostly using telescopes of the Young Exoplanet Transit Initiative. The analyses are used to refine the systems orbital parameters. In all cases we found no hints for significant TTVs, or changes in the system parameters inclination, fractional stellar radius and planet to star radius ratio. However, comparing our results with those available in the literature shows that we can confirm the already published values.
Published: 2015
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39. Tables of phase functions, opacities, albedos, equilibrium temperatures, and radiative accelerations of dust grains in exoplanets

Author: Budaj, Jan, Kocifaj, Miroslav, Salmeron, Raquel, and Hubeny, Ivan
Subjects: Astrophysics - Earth and Planetary Astrophysics
Abstract: There has been growing observational evidence for the presence of condensates in the atmospheres and/or comet-like tails of extrasolar planets. As a result, systematic and homogeneous tables of dust properties are useful in order to facilitate further observational and theoretical studies. In this paper we present calculations and analysis of non-isotropic phase functions, asymmetry parameter (mean cosine of the scattering angle), absorption and scattering opacities, single scattering albedos, equilibrium temperatures, and radiative accelerations of dust grains relevant for extrasolar planets. Our assumptions include spherical grain shape, Deirmendjian particle size distribution, and Mie theory. We consider several species: corundum/alumina, perovskite, olivines with 0\% and 50\% iron content, pyroxenes with 0\%, 20\% and 60\% iron content, pure iron, carbon at two different temperatures, water ice, liquid water, and ammonia. The presented tables cover the wavelength range of 0.2 to 500 micron and modal particle radii from 0.01 micron to 100 micron. Equilibrium temperatures and radiative accelerations assume irradiation by a non-black-body source of light with temperatures from 7000K to 700K seen at solid angles from 2$\pi$ to $10^{-6}$ sr. The tables are provided to the community together with a simple code which allows for an optional, finite, angular dimension of the source of light (star) in the phase function., Comment: 27 pages, 17 figures, our final version which appeared in 2015,MNRAS,454,2
Published: 2015
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40. The EChO science case

Author: Tinetti, Giovanna, Drossart, Pierre, Eccleston, Paul, Hartogh, Paul, Isaak, Kate, Linder, Martin, Lovis, Christophe, Micela, Giusi, Ollivier, Marc, Puig, Ludovic, Ribas, Ignasi, Snellen, Ignas, Allard, Bruce Swinyard. France, Barstow, Joanna, Cho, James, Coustenis, Athena, Cockell, Charles, Correia, Alexandre, Decin, Leen, de Kok, Remco, Deroo, Pieter, Encrenaz, Therese, Forget, Francois, Glasse, Alistair, Griffith, Caitlin, Guillot, Tristan, Koskinen, Tommi, Lammer, Helmut, Leconte, Jeremy, Maxted, Pierre, Mueller-Wodarg, Ingo, Nelson, Richard, North, Chris, Pallé, Enric, Pagano, Isabella, Piccioni, Guseppe, Pinfield, David, Selsis, Franck, Sozzetti, Alessandro, Stixrude, Lars, Tennyson, Jonathan, Turrini, Diego, Beaulieu, Mariarosa Zapatero-Osorio. Jean-Philippe, Grodent, Denis, Guedel, Manuel, Luz, David, Nørgaard-Nielsen, Hans Ulrik, Ray, Tom, Rickman, Hans, Selig, Avri, Banaszkiewicz, Mark Swain. Marek, Barlow, Mike, Bowles, Neil, Branduardi-Raymont, Graziella, Foresto, Vincent Coudé du, Gerard, Jean-Claude, Gizon, Laurent, Hornstrup, Allan, Jarchow, Christopher, Kerschbaum, Franz, Kovacs, Géza, Lagage, Pierre-Olivier, Lim, Tanya, Lopez-Morales, Mercedes, Malaguti, Giuseppe, Pace, Emanuele, Pascale, Enzo, Vandenbussche, Bart, Wright, Gillian, Adriani, Gonzalo Ramos Zapata. Alberto, Azzollini, Ruymán, Balado, Ana, Bryson, Ian, Burston, Raymond, Colomé, Josep, Crook, Martin, Di Giorgio, Anna, Griffin, Matt, Hoogeveen, Ruud, Ottensamer, Roland, Irshad, Ranah, Middleton, Kevin, Morgante, Gianluca, Pinsard, Frederic, Rataj, Mirek, Reess, Jean-Michel, Savini, Giorgio, Schrader, Jan-Rutger, Stamper, Richard, Abe, Berend Winter. L., Abreu, M., Achilleos, N., Ade, P., Adybekian, V., Affer, L., Agnor, C., Agundez, M., Alard, C., Alcala, J., Prieto, C. Allende, Floriano, F. J. Alonso, Altieri, F., Iglesias, C. A. Alvarez, Amado, P., Andersen, A., Aylward, A., Baffa, C., Bakos, G., Ballerini, P., Banaszkiewicz, M., Barber, R. J., Barrado, D., Barton, E. J., Batista, V., Bellucci, G., Avilés, J. A. Belmonte, Berry, D., Bézard, B., Biondi, D., Błęcka, M., Boisse, I., Bonfond, B., Bordé, P., Börner, P., Bouy, H., Brown, L., Buchhave, L., Budaj, J., Bulgarelli, A., Burleigh, M., Cabral, A., Capria, M. T., Cassan, A., Cavarroc, C., Cecchi-Pestellini, C., Cerulli, R., Chadney, J., Chamberlain, S., Charnoz, S., Jessen, N. Christian, Ciaravella, A., Claret, A., Claudi, R., Coates, A., Cole, R., Collura, A., Cordier, D., Covino, E., Danielski, C., Damasso, M., Deeg, H. J., Delgado-Mena, E., Del Vecchio, C., Demangeon, O., De Sio, A., De Wit, J., Dobrijévic, M., Doel, P., Dominic, C., Dorfi, E., Eales, S., Eiroa, C., Contreras, M. Espinoza, Esposito, M., Eymet, V., Fabrizio, N., Fernández, M., Castella, B. Femenía, Figueira, P., Filacchione, G., Fletcher, L., Focardi, M., Fossey, S., Fouqué, P., Frith, J., Galand, M., Gambicorti, L., Gaulme, P., López, R. J. García, Garcia-Piquer, A., Gear, W., Gerard, J. -C., Gesa, L., Giani, E., Gianotti, F., Gillon, M., Giro, E., Giuranna, M., Gomez, H., Gomez-Leal, I., Hernandez, J. Gonzalez, Merino, B. González, Graczyk, R., Grassi, D., Guardia, J., Guio, P., Gustin, J., Hargrave, P., Haigh, J., Hébrard, E., Heiter, U., Heredero, R. L., Herrero, E., Hersant, F., Heyrovsky, D., Hollis, M., Hubert, B., Hueso, R., Israelian, G., Iro, N., Irwin, P., Jacquemoud, S., Jones, G., Jones, H., Justtanont, K., Kehoe, T., Kerschbaum, F., Kerins, E., Kervella, P., Kipping, D., Koskinen, T., Krupp, N., Lahav, O., Laken, B., Lanza, N., Lellouch, E., Leto, G., Goldaracena, J. Licandro, Lithgow-Bertelloni, C., Liu, S. J., Cicero, U. Lo, Lodieu, N., Lognonné, P., Lopez-Puertas, M., Lopez-Valverde, M. A., Rasmussen, I. Lundgaard, Luntzer, A., Machado, P., MacTavish, C., Maggio, A., Maillard, J. -P., Magnes, W., Maldonado, J., Mall, U., Marquette, J. -B., Mauskopf, P., Massi, F., Maurin, A. -S., Medvedev, A., Michaut, C., Miles-Paez, P., Montalto, M., Rodríguez, P. Montañés, Monteiro, M., Montes, D., Morais, H., Morales, J. C., Morales-Calderón, M., Morello, G., Martín, A. Moro, Moses, J., Bedon, A. Moya, Alcaino, F. Murgas, Oliva, E., Orton, G., Palla, F., Pancrazzi, M., Pantin, E., Parmentier, V., Parviainen, H., Ramírez, K. Y. Peña, Peralta, J., Perez-Hoyos, S., Petrov, R., Pezzuto, S., Pietrzak, R., Pilat-Lohinger, E., Piskunov, N., Prinja, R., Prisinzano, L., Polichtchouk, I., Poretti, E., Radioti, A., Ramos, A. A., Rank-Lüftinger, T., Read, P., Readorn, K., López, R. Rebolo, Rebordão, J., Rengel, M., Rezac, L., Rocchetto, M., Rodler, F., Béjar, V. J. Sánchez, Lavega, A. Sanchez, Sanromá, E., Santos, N., Forcada, J. Sanz, Scandariato, G., Schmider, F. -X., Scholz, A., Scuderi, S., Sethenadh, J., Shore, S., Showman, A., Sicardy, B., Sitek, P., Smith, A., Soret, L., Sousa, S., Stiepen, A., Stolarski, M., Strazzulla, G., Tabernero, H. M, Tanga, P., Tecsa, M., Temple, J., Terenzi, L., Tessenyi, M., Testi, L., Thompson, S., Thrastarson, H., Tingley, B. W., Trifoglio, M., Torres, J. Martín, Tozzi, A., Turrini, D., Varley, R., Vakili, F., de Val-Borro, M., Valdivieso, M. L., Venot, O., Villaver, E., Vinatier, S., Viti, S., Waldmann, I., Waltham, D., Ward-Thompson, D., Waters, R., Watkins, C., Watson, D., Wawer, P., Wawrzaszk, A., White, G., Widemann, T., Winek, W., Wiśniowski, T., Yelle, R., Yung, Y., and Yurchenko, S. N.
Subjects: Astrophysics - Earth and Planetary Astrophysics
Abstract: The discovery of almost 2000 exoplanets has revealed an unexpectedly diverse planet population. Observations to date have shown that our Solar System is certainly not representative of the general population of planets in our Milky Way. The key science questions that urgently need addressing are therefore: What are exoplanets made of? Why are planets as they are? What causes the exceptional diversity observed as compared to the Solar System? EChO (Exoplanet Characterisation Observatory) has been designed as a dedicated survey mission for transit and eclipse spectroscopy capable of observing a large and diverse planet sample within its four-year mission lifetime. EChO can target the atmospheres of super-Earths, Neptune-like, and Jupiter-like planets, in the very hot to temperate zones (planet temperatures of 300K-3000K) of F to M-type host stars. Over the next ten years, several new ground- and space-based transit surveys will come on-line (e.g. NGTS, CHEOPS, TESS, PLATO), which will specifically focus on finding bright, nearby systems. The current rapid rate of discovery would allow the target list to be further optimised in the years prior to EChO's launch and enable the atmospheric characterisation of hundreds of planets. Placing the satellite at L2 provides a cold and stable thermal environment, as well as a large field of regard to allow efficient time-critical observation of targets randomly distributed over the sky. A 1m class telescope is sufficiently large to achieve the necessary spectro-photometric precision. The spectral coverage (0.5-11 micron, goal 16 micron) and SNR to be achieved by EChO, thanks to its high stability and dedicated design, would enable a very accurate measurement of the atmospheric composition and structure of hundreds of exoplanets., Comment: 50 pages, 30 figures. Experimental Astronomy
Published: 2015
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41. Presentation, care, coronary intervention and outcomes of patients with NSTEMI according to age: insights from the international prospective ACVC-EAPCI EORP NSTEMI registry.

Author: Nadarajah, Ramesh, Ludman, Peter, Laroche, Cécile, Appelman, Yolande, Brugaletta, Salvatore, Budaj, Andrzej, Bueno, Hector, Huber, Kurt, Kunadian, Vijay, Leonardi, Sergio, Lettino, Maddalena, Milasinovic, Dejan, Clegg, Andrew, and Gale, Chris P
Subjects: PEARSON correlation (Statistics), NON-ST elevated myocardial infarction, MEDICAL quality control, SCIENTIFIC observation, KRUSKAL-Wallis Test, FISHER exact test, TREATMENT effectiveness, AGE distribution, DESCRIPTIVE statistics, CHI-squared test, LONGITUDINAL method, RESEARCH, CORONARY angiography, DATA analysis software
Abstract: Background Older people less frequently receive invasive coronary angiography (ICA) for NSTEMI than younger patients. We describe care, ICA data, and in-hospital and 30-day outcomes of NSTEMI by age in a contemporary and geographically diverse cohort. Methods Prospective cohort study including 2947 patients with NSTEMI from 287 centres in 59 countries, stratified by age (≥75 years, n = 761). Quality of care was evaluated based on 12 guideline-recommended care interventions, and data collected on ICA. Outcomes included in hospital acute heart failure, cardiogenic shock, repeat myocardial infarction, stroke/transient ischaemic attack, BARC Type ≥3 bleeding and death, as well as 30-day mortality. Results Patients aged ≥75 years, compared with younger patients, at presentation had a higher prevalence of comorbidities and oral anticoagulation prescription (22.4% vs 7.6%, p < 0.001). Older patients less frequently received ICA than younger patients (78.6% vs 90.6%, p < 0.001) with the recorded reason more often being advanced age, comorbidities or frailty. Of those who underwent ICA, older patients more frequently demonstrated 3-vessel, 4-vessel and/or left main stem coronary artery disease compared to younger patients (49.7% vs 34.1%, p < 0.001) but less frequently received revascularisation (63.6% vs 76.9%, p < 0.001). Older patients experienced higher rates of in-hospital acute heart failure (15.0% vs 8.4%, p < 0.001) and bleeding (2.8% vs 1.3%, p = 0.006), as well as in-hospital and 30-day mortality (3.4% vs 1.3%, p < 0.001; 4.8% vs 1.7%, p < 0.001; respectively), than younger patients. Conclusions Patients aged ≥75 years with NSTEMI, compared with younger patients, less frequently received ICA and guideline-recommended care, and had worse short-term outcomes. [ABSTRACT FROM AUTHOR]
Published: 2024
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42. Factor XI inhibition in cardiovascular disease.

Author: Carlin, Stephanie, Jakovac, Michael, Budaj, Andrzej, and Eikelboom, John
Published: 2024
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43. TransRadial versus transUlnar artery approach for elective invasive percutaneous coronary interventions: a randomized trial on the feasibility and safety with ultrasonographic outcome – RAUL study

Author: Dagmara Gralak-Lachowska, Paweł Lewandowski, Pawel Maciejewski, Bogumił Ramotowski, Andrzej Budaj, and Sebastian Stec
Subjects: transulnar access, complications, ultrasonography, Medicine
Published: 2020
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44. ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial

Author: Ueland, Thor, Åkerblom, Axel, Ghukasyan, Tatevik, Michelsen, Annika E., Becker, Richard C., Bertilsson, Maria, Budaj, Andrzej, Cornel, Jan H., Himmelmann, Anders, James, Stefan K., Siegbahn, Agneta, Storey, Robert F., Kontny, Frederic, Aukrust, Pål, and Wallentin, Lars
Published: 2020
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45. Studying of exoasteroids orbiting around WD 1145+017

Author: Maliuk, A., primary, Budaj, J., additional, Mkrtichian, D., additional, Garai, Z., additional, Zharikov, S., additional, Pribulla, T., additional, Komžík, R., additional, Kusakin, A., additional, Shestakova, L., additional, Kokumbaeva, R., additional, Reva, I., additional, Joshi, S., additional, Valeev, A., additional, Gadelshin, D., additional, Valyavin, G., additional, A-thano, N., additional, Mennickent, R., additional, Serebryanskiy, A., additional, and Kaye, T.G., additional
Published: 2024
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46. Strategy of lipid-lowering treatment in patients with acute coronary syndrome. The ELECTRA-SIRIO 2 investigators’ viewpoint

Author: Kubica, Jacek, primary, Banach, Maciej, additional, Adamski, Piotr, additional, Budaj, Andrzej, additional, Buszman, Piotr, additional, Di Somma, Salvatore, additional, Gabulova, Rahima, additional, Gajda, Robert, additional, Gurbel, Paul A., additional, Kosobucka-Ozdoba, Agata, additional, Konarski, Jacek, additional, Kubica, Aldona, additional, Magielski, Przemysław, additional, Niezgoda, Piotr, additional, Ostrowska, Małgorzata, additional, Piasecki, Maciej, additional, Rahimov, Uzeyir, additional, Tantry, Udaya, additional, Umińska, Julia M., additional, and Navarese, Eliano P., additional
Published: 2024
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47. Egzamin z kardiologii. Tom 1

Author: Balsam, Paweł, primary, Bielecka-Dąbrowa, Agata, additional, Błach, Anna, additional, Brociek, Emil, additional, Budaj-Fidecka, Anna, additional, Byczkowska, Katarzyna, additional, Chabior, Aleksandra, additional, Cichocka-Radwan, Anna, additional, Czepczor, Kinga, additional, Dobrowolski, Piotr, additional, Domienik-Karłowicz, Justyna, additional, Drożdż, Jarosław, additional, Filipiak-Strzecka, Dominika, additional, Gabryel, Łukasz, additional, Galas, Agata, additional, Gąsior, Zbigniew, additional, Gierlotka, Marek, additional, Góral, Piotr, additional, Holcman, Katarzyna, additional, Imiela, Anna, additional, Imiela, Tomasz, additional, Januszewicz, Andrzej, additional, Januszewicz, Magdalena, additional, Jedrzejczyk-Patej, Ewa, additional, Kapłon-Cieślicka, Agnieszka, additional, Kasperowicz, Krzysztof, additional, Kępski, Jarosław, additional, Kopeć, Grzegorz, additional, Kosiński, Przemysław, additional, Kozłowska, Bogna, additional, Krzesiński, Paweł, additional, Krzowski, Bartosz, additional, Kupczyńska, Karolina, additional, Kurzyna, Marcin, additional, Kuśmierczyk, Mariusz, additional, Lelonek, Małgorzata, additional, Lenarczyk, Radosław, additional, Leszek, Przemysław, additional, Lipiec, Piotr, additional, Mazurek, Michał, additional, Mielczarek, Szymon, additional, Mizia-Stec, Katarzyna, additional, Morawiec, Robert, additional, Nowak, Marcin M., additional, Ochijewicz, Dorota, additional, Opolski, Grzegorz, additional, Ozierański, Krzysztof, additional, Pasierski, Michał, additional, Pawlak, Agnieszka, additional, Piątkowski, Radosław, additional, Podolski, Maciej, additional, Prejbisz, Aleksander, additional, Pyziak-Stepień, Marta, additional, Rajska, Ewa, additional, Rubiś, Paweł, additional, Rymuza, Bartosz, additional, Sacha, Jerzy, additional, Skrobucha, Alicja, additional, Słomka, Sebastian, additional, Sobieszczańska-Małek, Małgorzata, additional, Sokolska, Justyna M., additional, Stępniewski, Jakub, additional, Suwalski, Piotr, additional, Szczerba, Ewa, additional, Szmit, Sebastian, additional, Szymański, Piotr, additional, Tomaszek, Aleksandra, additional, Torbicki, Adam, additional, Tymińska, Agata, additional, Wieteska-Mirek, Maria, additional, Witowicz, Anna, additional, Wojakowski, Wojciech, additional, Wrona, Katarzyna, additional, Załęska-Kocięcka, Marta, additional, Zawadka, Mateusz, additional, and Żurawska, Małgorzata, additional
Published: 2024
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48. Egzamin z kardiologii. Tom 3

Author: Balsam, Paweł, primary, Blamek, Sławomir, additional, Błach, Anna, additional, Braksator, Wojciech, additional, Budaj-Fidecka, Anna, additional, Budnik, Monika, additional, Burban, Anna, additional, Ciepłucha, Aleksandra, additional, Ciurzyński, Michał, additional, Czupryniak, Leszek, additional, Darocha, Szymon, additional, Dąbrowski, Rafał, additional, Dorniak, Karolina, additional, Dyrbuś, Maciej, additional, Dziewięcka, Ewa, additional, Elwertowski, Michał, additional, Ferens, Antoni, additional, Fojt, Anna, additional, Gackowski, Andrzej, additional, Gajewska, Magdalena, additional, Gajos, Grzegorz, additional, Gałązka, Zbigniew, additional, Gawałko, Monika, additional, Gąsecka, Aleksandra, additional, Główczynska, Renata, additional, Grabowski, Marcin, additional, Grodecki, Kajetan, additional, Haberka, Maciej, additional, Huczek, Zenon, additional, Januszkiewicz, Łukasz, additional, Jędrzejczyk-Patej, Ewa, additional, Jonik, Szymon, additional, Kapłon-Cieślicka, Agnieszka, additional, Kaszczewski, Piotr, additional, Kazimierczyk, Ewelina, additional, Kazimierczyk, Remigiusz, additional, Kępka, Cezary, additional, Kobylecka, Małgorzata, additional, Kochman, Janusz, additional, Kołodzińska, Agnieszka, additional, Kołtowski, Łukasz, additional, Konwerski, Michał, additional, Kosek-Nikołajczuk, Małgorzata, additional, Kowalik, Robert, additional, Kowara, Michał, additional, Kozyra-Pydyś, Eliza, additional, Koźluk, Edward, additional, Król, Wojciech, additional, Krzowski, Bartosz, additional, Kupczyńska, Karolina, additional, Kurnicka, Katarzyna, additional, Kuśmierczyk, Mariusz, additional, Kwieciński, Jacek, additional, Lenarczyk, Radosław, additional, Lichodziejewska, Barbara, additional, Lodziński, Piotr, additional, Maciejewski, Cezary, additional, Małecki, Robert, additional, Małyszko, Jolanta, additional, Mamcarz, Artur, additional, Marchel, Michał, additional, Mazurek, Maciej, additional, Mazurek, Michał, additional, Męcka, Klaudia, additional, Miśkowiec, Dawid, additional, Mizia-Stec, Katarzyna, additional, Ochotny, Romuald, additional, Opolski, Maksymilian P., additional, Oręziak, Artur, additional, Orszulak, Michał, additional, Ostrowska, Ewa, additional, Ozierański, Krzysztof, additional, Pachciński, Olaf, additional, Pasierski, Michał, additional, Peller, Michał, additional, Petryka-Mazurkiewicz, Joanna, additional, Piątkowska, Agnieszka, additional, Piotrowicz, Ewa, additional, Piotrowicz, Ryszard, additional, Pruszczyk, Piotr, additional, Rajewska-Tabor, Justyna, additional, Rogozik, Joanna, additional, Rogula, Sylwester, additional, Rokicki, Jakub, additional, Ryś-Czaporowska, Anna, additional, Stępień-Adamczewska, Violetta, additional, Stępińska, Janina, additional, Strzelczyk, Jakub, additional, Styczyński, Grzegorz, additional, Suwalski, Piotr, additional, Szczałuba, Krzysztof, additional, Szczerba, Ewa, additional, Śpiewak, Mateusz, additional, Świerżyńska, Ewa, additional, Tajstra, Mateusz, additional, Tomaniak, Mariusz, additional, Tycińska, Agnieszka, additional, Tymińska, Agata, additional, Wełnicki, Marcin, additional, Winciunas, Piotr Artur, additional, and Zaleska, Martyna, additional
Published: 2024
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49. High-precision photometry by telescope defocussing. VII. The ultra-short period planet WASP-103

Author: Southworth, John, Mancini, L., Ciceri, S., Budaj, J., Dominik, M., Jaimes, R. Figuera, Haugbolle, T., Jorgensen, U. G., Popovas, A., Rabus, M., Rahvar, S., von Essen, C., Schmidt, R. W., Wertz, O., Alsubai, K. A., Bozza, V., Bramich, D. M., Novati, S. Calchi, D'Ago, G., Hinse, T. C., Henning, Th., Hundertmark, M., Juncher, D., Korhonen, H., Skottfelt, J., Snodgrass, C., Starkey, D., and Surdej, J.
Subjects: Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract: We present 17 transit light curves of the ultra-short period planetary system WASP-103, a strong candidate for the detection of tidally-induced orbital decay. We use these to establish a high-precision reference epoch for transit timing studies. The time of the reference transit midpoint is now measured to an accuracy of 4.8s, versus 67.4s in the discovery paper, aiding future searches for orbital decay. With the help of published spectroscopic measurements and theoretical stellar models, we determine the physical properties of the system to high precision and present a detailed error budget for these calculations. The planet has a Roche lobe filling factor of 0.58, leading to a significant asphericity; we correct its measured mass and mean density for this phenomenon. A high-resolution Lucky Imaging observation shows no evidence for faint stars close enough to contaminate the point spread function of WASP-103. Our data were obtained in the Bessell $RI$ and the SDSS $griz$ passbands and yield a larger planet radius at bluer optical wavelengths, to a confidence level of 7.3 sigma. Interpreting this as an effect of Rayleigh scattering in the planetary atmosphere leads to a measurement of the planetary mass which is too small by a factor of five, implying that Rayleigh scattering is not the main cause of the variation of radius with wavelength., Comment: Accepted for publication in MNRAS. 12 pages, 8 tables, 7 figures. The reduced data will be available at http://www.astro.keele.ac.uk/~jkt/data-teps.html
Published: 2014
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50. Search for a circum-planetary material and orbital period variations of short-period Kepler exoplanet candidates

Author: Garai, Z., Zhou, G., Budaj, J., and Stellingwerf, R. F.
Subjects: Astrophysics - Earth and Planetary Astrophysics
Abstract: A unique short-period Mercury-size Kepler exoplanet candidate KIC012557548b has been discovered recently by Rappaport et al. (2012). This object is a transiting disintegrating exoplanet with a circum-planetary material - comet-like tail. Close-in exoplanets, like KIC012557548b, are subjected to the greatest planet-star interactions. This interaction may have various forms. In certain cases it may cause formation of the comet-like tail. Strong interaction with the host star, and/or presence of an additional planet may lead to variations in the orbital period of the planet. Our main aim is to search for comet-like tails similar to KIC012557548b and for long-term orbital period variations. We are curious about frequency of comet-like tail formation among short-period Kepler exoplanet candidates. We concentrate on a sample of 20 close-in candidates with a period similar to KIC012557548b from the Kepler mission., Comment: 19 pages, 75 figures, AN accepted
Published: 2014
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