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23 results on '"Brusadelli, Marion"'

1. Single cell transcriptomic analysis of HPV16-infected epithelium identifies a keratinocyte subpopulation implicated in cancer

Author

Bedard, Mary C., Chihanga, Tafadzwa, Carlile, Adrean, Jackson, Robert, Brusadelli, Marion G., Lee, Denis, VonHandorf, Andrew, Rochman, Mark, Dexheimer, Phillip J., Chalmers, Jeffrey, Nuovo, Gerard, Lehn, Maria, Williams, David E. J., Kulkarni, Aditi, Carey, Molly, Jackson, Amanda, Billingsley, Caroline, Tang, Alice, Zender, Chad, Patil, Yash, Wise-Draper, Trisha M., Herzog, Thomas J., Ferris, Robert L., Kendler, Ady, Aronow, Bruce J., Kofron, Matthew, Rothenberg, Marc E., Weirauch, Matthew T., Van Doorslaer, Koenraad, Wikenheiser-Brokamp, Kathryn A., Lambert, Paul F., Adam, Mike, Steven Potter, S., and Wells, Susanne I.

Published
2023
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5. Supplemental Figure 3 from Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling

Author

Romick-Rosendale, Lindsey E., primary, Hoskins, Elizabeth E., primary, Privette Vinnedge, Lisa M., primary, Foglesong, Grant D., primary, Brusadelli, Marion G., primary, Potter, S. Steven, primary, Komurov, Kakajan, primary, Brugmann, Samantha A., primary, Lambert, Paul F., primary, Kimple, Randall J., primary, Virts, Elizabeth L., primary, Hanenberg, Helmut, primary, Gillison, Maura L., primary, and Wells, Susanne I., primary

Published
2023
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6. Supplementary Figure and Table Legends from Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling

Author

Romick-Rosendale, Lindsey E., primary, Hoskins, Elizabeth E., primary, Privette Vinnedge, Lisa M., primary, Foglesong, Grant D., primary, Brusadelli, Marion G., primary, Potter, S. Steven, primary, Komurov, Kakajan, primary, Brugmann, Samantha A., primary, Lambert, Paul F., primary, Kimple, Randall J., primary, Virts, Elizabeth L., primary, Hanenberg, Helmut, primary, Gillison, Maura L., primary, and Wells, Susanne I., primary

Published
2023
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7. Supplemental Table 2 from Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling

Author

Romick-Rosendale, Lindsey E., primary, Hoskins, Elizabeth E., primary, Privette Vinnedge, Lisa M., primary, Foglesong, Grant D., primary, Brusadelli, Marion G., primary, Potter, S. Steven, primary, Komurov, Kakajan, primary, Brugmann, Samantha A., primary, Lambert, Paul F., primary, Kimple, Randall J., primary, Virts, Elizabeth L., primary, Hanenberg, Helmut, primary, Gillison, Maura L., primary, and Wells, Susanne I., primary

Published
2023
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8. Supplemental Table 1 from Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling

Author

Romick-Rosendale, Lindsey E., primary, Hoskins, Elizabeth E., primary, Privette Vinnedge, Lisa M., primary, Foglesong, Grant D., primary, Brusadelli, Marion G., primary, Potter, S. Steven, primary, Komurov, Kakajan, primary, Brugmann, Samantha A., primary, Lambert, Paul F., primary, Kimple, Randall J., primary, Virts, Elizabeth L., primary, Hanenberg, Helmut, primary, Gillison, Maura L., primary, and Wells, Susanne I., primary

Published
2023
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9. Supplemental Figure 1 from Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling

Author

Romick-Rosendale, Lindsey E., primary, Hoskins, Elizabeth E., primary, Privette Vinnedge, Lisa M., primary, Foglesong, Grant D., primary, Brusadelli, Marion G., primary, Potter, S. Steven, primary, Komurov, Kakajan, primary, Brugmann, Samantha A., primary, Lambert, Paul F., primary, Kimple, Randall J., primary, Virts, Elizabeth L., primary, Hanenberg, Helmut, primary, Gillison, Maura L., primary, and Wells, Susanne I., primary

Published
2023
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10. Supplemental Figure 2 from Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling

Author

Romick-Rosendale, Lindsey E., primary, Hoskins, Elizabeth E., primary, Privette Vinnedge, Lisa M., primary, Foglesong, Grant D., primary, Brusadelli, Marion G., primary, Potter, S. Steven, primary, Komurov, Kakajan, primary, Brugmann, Samantha A., primary, Lambert, Paul F., primary, Kimple, Randall J., primary, Virts, Elizabeth L., primary, Hanenberg, Helmut, primary, Gillison, Maura L., primary, and Wells, Susanne I., primary

Published
2023
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12. Data from Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling

Author

Romick-Rosendale, Lindsey E., primary, Hoskins, Elizabeth E., primary, Privette Vinnedge, Lisa M., primary, Foglesong, Grant D., primary, Brusadelli, Marion G., primary, Potter, S. Steven, primary, Komurov, Kakajan, primary, Brugmann, Samantha A., primary, Lambert, Paul F., primary, Kimple, Randall J., primary, Virts, Elizabeth L., primary, Hanenberg, Helmut, primary, Gillison, Maura L., primary, and Wells, Susanne I., primary

Published
2023
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13. Supplemental Figure 4 from Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling

Author

Romick-Rosendale, Lindsey E., primary, Hoskins, Elizabeth E., primary, Privette Vinnedge, Lisa M., primary, Foglesong, Grant D., primary, Brusadelli, Marion G., primary, Potter, S. Steven, primary, Komurov, Kakajan, primary, Brugmann, Samantha A., primary, Lambert, Paul F., primary, Kimple, Randall J., primary, Virts, Elizabeth L., primary, Hanenberg, Helmut, primary, Gillison, Maura L., primary, and Wells, Susanne I., primary

Published
2023
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15. Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin

Author

Ruiz-Torres, Sonya, Brusadelli, Marion G., Witte, David P., Wikenheiser-Brokamp, Kathryn A., Sauter, Sharon, Nelson, Adam S., Sertorio, Mathieu, Chlon, Timothy M., Lane, Adam, Mehta, Parinda A., Myers, Kasiani C., Bedard, Mary C., Pal, Bidisha, Supp, Dorothy M., Lambert, Paul F., Komurov, Kakajan, Kovacic, Melinda Butsch, Davies, Stella M., and Wells, Susanne I.

Published
2021
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16. HPV Strain Predicts Severity of Juvenile-Onset Recurrent Respiratory Papillomatosis with Implications for Disease Screening

Author

Bedard, Mary C., primary, de Alarcon, Alessandro, additional, Kou, Yann-Fuu, additional, Lee, David, additional, Sestito, Alexandra, additional, Duggins, Angela L., additional, Brusadelli, Marion, additional, Lane, Adam, additional, Wikenheiser-Brokamp, Kathryn A., additional, Wells, Susanne I., additional, and Smith, David F., additional

Published
2021
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17. Human Papillomavirus Oral- and Sero- Positivity in Fanconi Anemia

Author

Sauter, Sharon L., primary, Zhang, Xue, additional, Romick-Rosendale, Lindsey, additional, Wells, Susanne I., additional, Myers, Kasiani C., additional, Brusadelli, Marion G., additional, Poff, Charles B., additional, Brown, Darron R., additional, Panicker, Gitika, additional, Unger, Elizabeth R., additional, Mehta, Parinda A., additional, Bleesing, Jack, additional, Davies, Stella M., additional, and Butsch Kovacic, Melinda, additional

Published
2021
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18. Patient-Derived Organotypic Epithelial Rafts Model Phenotypes in Juvenile-Onset Recurrent Respiratory Papillomatosis

Author

Bedard, Mary C., primary, Brusadelli, Marion G., additional, Carlile, Adrean, additional, Ruiz-Torres, Sonya, additional, Lodin, Hannah, additional, Lee, Denis, additional, Kofron, Matthew, additional, Lambert, Paul F., additional, Lane, Adam, additional, Ameziane, Najim, additional, Bahassi, El Mustapha, additional, Wikenheiser-Brokamp, Kathryn A., additional, de Alarcon, Alessandro, additional, Smith, David F., additional, and Wells, Susanne I., additional

Published
2021
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19. Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma

Author

Toptan, Tuna, Brusadelli, Marion G., Turpin, Brian, Witte, David P., Surrallés i Calonge, Jordi, Velleuer, Eunike, Schramm, Martin, Dietrich, Ralf, Brakenhoff, Ruud H., Moore, Patrick S., Chang, Yuan, Wells, Susanne I., Universitat Autònoma de Barcelona, CCA - Imaging and biomarkers, CCA - Cancer biology and immunology, Otolaryngology / Head & Neck Surgery, and AII - Inflammatory diseases

Subjects
0301 basic medicine, Genome instability, Viral Diseases, Skin Neoplasms, viruses, Cell, Artificial Gene Amplification and Extension, Pathology and Laboratory Medicine, Polymerase Chain Reaction, 0302 clinical medicine, Fanconi anemia, Medicine and Health Sciences, Skin Tumors, Staining, education.field_of_study, Multidisciplinary, Squamous Cell Carcinomas, Head and Neck Tumors, 3. Good health, Infectious Diseases, medicine.anatomical_structure, Oncology, Medical Microbiology, Viral Pathogens, 030220 oncology & carcinogenesis, Viruses, Medicine, Immunohistochemistry, Pathogens, Polyomavirus, Research Article, Human Papillomavirus Infection, Science, Urology, Population, Sexually Transmitted Diseases, Dermatology, Research and Analysis Methods, Microbiology, Carcinomas, 03 medical and health sciences, Head and Neck Squamous Cell Carcinoma, Cell Line, Tumor, medicine, Humans, Basal cell, Molecular Biology Techniques, education, Microbial Pathogens, Molecular Biology, Immunohistochemistry Techniques, Polyomavirus Infections, Biology and life sciences, Squamous Cell Carcinoma of Head and Neck, Genitourinary Infections, business.industry, Head and neck cancer, Organisms, Cancers and Neoplasms, medicine.disease, Head and neck squamous-cell carcinoma, Polyomaviruses, Histochemistry and Cytochemistry Techniques, Nuclear Staining, Tumor Virus Infections, stomatognathic diseases, Fanconi Anemia, HEK293 Cells, 030104 developmental biology, Head and Neck Cancers, Specimen Preparation and Treatment, Immunologic Techniques, Cancer research, DNA viruses, business
Abstract

Fanconi anemia is a rare genome instability disorder with extreme susceptibility to squamous cell carcinoma of the head and neck and anogenital tract. In patients with this inherited disorder, the risk of head and neck cancer is 800-fold higher than in the general population, a finding which might suggest a viral etiology. Here, we analyzed the possible contribution of human polyomaviruses to FA-associated head and neck squamous cell carcinoma (HNSCC) by a pan-polyomavirus immunohistochemistry test which detects the T antigens of all known human polyomaviruses. We observed weak reactivity in 17% of the HNSCC samples suggesting that based on classical criteria, human polyomaviruses are not causally related to squamous cell carcinomas analyzed in this study.

Published
2018
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21. Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling

Author

Romick-Rosendale, Lindsey E., primary, Hoskins, Elizabeth E., additional, Privette Vinnedge, Lisa M., additional, Foglesong, Grant D., additional, Brusadelli, Marion G., additional, Potter, S. Steven, additional, Komurov, Kakajan, additional, Brugmann, Samantha A., additional, Lambert, Paul F., additional, Kimple, Randall J., additional, Virts, Elizabeth L., additional, Hanenberg, Helmut, additional, Gillison, Maura L., additional, and Wells, Susanne I., additional

Published
2016
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22. TGFβ signaling regulates lipogenesis in human sebaceous glands cells

Author

McNairn, Adrian J, primary, Doucet, Yanne, additional, Demaude, Julien, additional, Brusadelli, Marion, additional, Gordon, Christopher B, additional, Uribe-Rivera, Armando, additional, Lambert, Paul F, additional, Bouez, Charbel, additional, Breton, Lionel, additional, and Guasch, Géraldine, additional

Published
2013
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23. Signaling moderation: TGF-β in exocrine gland development, maintenance, and regulation.

Author

McNairn AJ, Brusadelli M, and Guasch G

Abstract

The TGF-β superfamily is involved in embryonic development and regulation of many cellular processes. Importantly, these signaling molecules have been increasingly revealed to play a crucial role in exocrine gland maintenance and regulation. TGF-β is involved in controlling the branching morphogenesis that is common to most exocrine glands, including: mammary gland, salivary, prostate, and in sebaceous gland regulation. In this review, we explore the molecular mechanisms and uses of TGF-β in crafting the microenvironment of epithelial tissues surrounding these exocrine glands and how perturbations in the signaling pathway affect their differentiation and proper development.

Published
2013
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