1. Evaluation of immunological, inflammatory, and oxidative stress biomarkers in gasoline station attendants
- Author
-
Angela Maria Moro, Elisa Sauer, Natália Brucker, Mariele Feiffer Charão, Bruna Gauer, Sabrina Nunes do Nascimento, Gabriela Goethel, Marta Maria Medeiros Frescura Duarte, and Solange Cristina Garcia
- Subjects
Occupational toxicology ,Benzene ,Toluene ,Xylene ,CD80 ,CD86 ,Therapeutics. Pharmacology ,RM1-950 ,Toxicology. Poisons ,RA1190-1270 - Abstract
Abstract Background Gasoline is a complex mixture of saturated and unsaturated hydrocarbons, in which aromatic compounds, such as BTX (benzene, toluene, and xylene) feature as the main constituents. Simultaneous exposure to these aromatic hydrocarbons causes a significant impact on benzene toxicity. In order to detect early alterations caused in gasoline station attendants exposed to BTX compounds, immunological, inflammatory, and oxidative stress biomarkers were evaluated. Methods A total of 66 male subjects participated in this study. The gasoline station attendants (GSA) group consisted of 38 gasoline station attendants from Rio Grande do Sul, Brazil. The non-exposed group consisted of 28 subjects who were non-smokers and who had no history of occupational exposure. Environmental and biological monitoring of BTX exposure was performed using blood and urine. Results The GSA group showed increased BTX concentrations in relation to the non-exposed group (p
- Published
- 2019
- Full Text
- View/download PDF