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This study aims to validate sanitation standard operating procedures (SSOPs) of the precooling system in two immersion stages with different temperatures followed by dripping for 3 min. The variables evaluated were temperature, weight, microbiological quality, and safety of chicken carcasses. Groups of indicator microorganisms were quantified and the occurrence of Salmonella spp., Listeria monocytogenes, diarrheagenic Escherichia coli (non-157), and Staphylococcus aureus with enterotoxigenic potential was investigated, before and after cooling by immersion and dripping. Salmonella serovars were determined by real-time PCR. Immersion of the carcasses in water at 9.5 (±2.89) and 2.33 (±1.30) °C in the first and second stages was sufficient to considerably reduce the carcass temperature to 5.70 and 7.41 °C at the system outlet and after dripping, respectively. The weight gain was 5.5%, in accordance with Brazilian legislation (

Realizou-se uma revisão sistemática qualitativa da literatura sobre como as Psicoterapias Humanistas, Fenomenológicas e Existenciais têm lidado com o método fenomenológico com relação à pesquisa qualitativa em Psicologia e à prática clínica, visando averiguar como procedem. Selecionou-se artigos em português, completos e referentes ao período de 2011 a 2021, a partir de buscas nas bases de dados LILACS, PePSIC e SciELO-Brasil. Como palavras chave: (método fenomenológico) AND (psicoterapia OR clínica). O corpus foi constituído por 45 artigos, os quais foram analisados quanti (Distribuição de artigos publicados; Desempenho dos periódicos brasileiros; Ranque dos psicólogos com maior índice de publicação; Filiações institucionais dos autores e coautores) e qualitativamente em função das dimensões: (I) desenho metodológico empregado, (II) análise de dados, (III) método fenomenológico no fazer terapêutico. Os resultados apontam: maior produção de artigos em 2020; concentração de publicações em um periódico de orientação humanista; predominância de autores e universidades cearenses e predominância de produções empíricas. O instrumento mais utilizado para coleta de dados a entrevista semiestruturada; para análise de dados muito se recorreu ao proposto por Giorgi e Sousa (2010), sendo o método de análise mais citado nas pesquisas o fenomenológico existencial-hermenêutico, que se baseou em diferentes autores. Os conceitos filosóficos propostos por Husserl aparecem de forma diferente daquela explorada pelo filósofo, aparecendo como: postura (profissional), atitude de compreensão tomada pelo psicólogo, evidenciando seu modo de intervenção. Ainda, os autores tratam como sinônimos as ideias de epoché, redução, redução fenomenológica, com um significado geral de atitude/postura. Parece incoerente aplicar o método fenomenológico diretamente como recurso psicoterapêutico, tendo em vista sua elaboração e desenvolvimento como método de investigação e validação dos fenômenos, tarefa particularmente introspectiva, racional e reflexiva.

ABSTRACT Objective: This study aimed to review the literature on the types of treatments proposed for patients with bruxism and implant supported, discussing a treatment protocol for those patients, for the purpose of prolonging the treatment longevity. Methods: A literature search in MEDLINE (PubMed), Google Scholar and SciELO databases, with the analysis of the literature published between 2006 and 2024. The descriptors used were “bruxism” and “dental implants” and “Dental Prosthesis, Implant-Supported”. Results: A total of 47 articles were identified in the PubMed online database, 24 in Google Scholar, 1 in SciELO, with a total of 72 articles. After reading the titles and abstracts, 56 works were selected, which were read in full. After full analysis of the studies and application of the inclusion and exclusion criteria, 13 articles remained that were included in this review. Conclusion: The study discusses the key factors to success of implant supported prosthesis treatment in patients with bruxism, which is a relevant risk factor for implant failure. The characteristics of the implant, such as the surface, modulus of elasticity, grade of titanium, diameter, length, location of the implant, implant-protected occlusion, type of prosthesis material and the need for an occlusal splint.

Introdução: as atividades laborais incorporam elementos físicos, sociais, emocionais e técnicos. Em um cenário de constantes transformações, compreender a atualidade científica sobre a estrutura e sobre as circunstâncias laborais dos enfermeiros na Atenção Primária a Saúde (APS) se revela como imperativo. Objetivo: identificar, na literatura científica, os aspectos relacionados ao ambiente de trabalho que influenciam a atuação dos enfermeiros inseridos na APS. Materiais e método: trata-se de revisão integrativa da literatura realizada em agosto de 2023 nas bases de dados Lilacs, Cinahl, Web of Science, Medline, Scopus e Embase, seguindo as recomendações do The Prisma 2020 Statement. Os critérios de inclusão foram artigos eletrônicos completos, em português, inglês ou espanhol, publicados entre 2019 e 2023. A presente revisão utilizou o instrumento Robis para avaliar o risco de viés. Resultados: a pesquisa identificou 1417 registros nas bases de dados, dos quais 20 foram selecionados para a amostra final. Desses, 30 % foram de 2020 (n = 6), em português, inglês e espanhol. O Brasil teve o maior número de publicações, com 55 % (n = 11), e os estudos qualitativos representaram 55 % (n = 11) na abordagem metodológica. Emergiram da análise as categorias temáticas “elementos psíquicos e emocionais”, “recursos humanos, materiais e infraestrutura”, “relações interpessoais”, “insatisfação”, “violência no local de trabalho” e “sobrecarga”. Conclusões: o ambiente precário na APS impacta negativamente os enfermeiros e os cuidados a população. Melhorias na infraestrutura, na equipe e nas condições de trabalho são essenciais para garantir a qualidade no cuidado.

This study investigates cyclone dynamics and impacts in the Southwestern Atlantic, with a focus on their effects on southern Brazil. As climate change intensifies coastal vulnerability, understanding cyclone behavior has become essential. Using the TRACK and cycloTRACK algorithms, we examined cyclone trajectories and cyclogenesis densities from 1979 to 2019 to analyze seasonal and spatial patterns shaped by large-scale atmospheric circulations, including the Antarctic Oscillation (AAO). The analysis explores trends in cyclone activity across various temporal and spatial scales, identifying key regions of cyclogenesis and trajectory density. Results indicate that the cycloTRACK algorithm is more effective at tracking more intense and consistent cyclones, excluding weaker systems. Seasonal patterns suggest variability in cyclone formation, likely associated with atmospheric instability and ocean–atmosphere interactions. While trends reveal an increase in cyclone passages in southern Brazil, these systems are strongly associated with extreme climatic events in the region, including coastal storms, intense precipitation, strong winds, and high waves. By clarifying cyclone dynamics and seasonal patterns, this study enhances our understanding of cyclone behavior and contributes to improved assessments of regional climate resilience in southern Brazil.

Abstract Lycopene (LYC), a carotenoid extracted mainly from tomatoes, has several biological properties, making its use desirable as a nutraceutical and pharmaceutical active ingredient. Among its various applications vulvovaginal candidiasis stands out. However, the use of LYC in therapy has limitations related to its solubility and stability. In this study, mesoporous silica nanoparticles (MSNs) are used to load and protect LYC from degradation. The exact amount of drug incorporated was determined by analytical techniques, such as high‐performance liquid chromatography (HPLC) and thermal analysis. For this, we developed and validated an HPLC method for LYC quantification and evaluated LYC impregnation in MSNs, followed by thermogravimetry analysis (TGA). Differential scanning calorimetry (DSC) was also used in order to confirm drug incorporation. Additionally, an in vitro release study in simulated vaginal fluid was also carried out. The HPLC method was duly validated for the range of 26–125 µg mL−1 and proved to be suitable for LYC quantification. DSC measurements suggest an improvement in the stability of the impregnated drug, which was reinforced by the release assay. Overall, the developed method is suitable to quantify LYC‐loaded porous materials enabling its use in vaginal applications.

Studies on land-use and land-cover change patterns contribute to better informed management decisions for the conservation and restoration of Atlantic Forest fragments and their megabiodiversity. In recent decades, the phenomenon of forest transition has been observed in several parts of the biome, including in highly urbanized and metropolitan areas such as Campinas, in the state of São Paulo. Here, we examine land-use and land-cover change (using MapBiomas data with 30 m spatial resolution) within the Campinas Environmental Protection Area, where natural forest cover increased from 9% to 17.1% of the total area between 1985 and 2023. Exogenous socioeconomic factors, including the gradual replacement of agricultural activities by tourism development and the designation of areas through successive ecological–economic zonings, are presented as possible causes of the decrease in deforestation and the stabilization and recovery of the remaining natural forest cover. Our analysis reaffirms evidence from other studies showing that secondary succession in abandoned pastures contributed to the forest transition process identified in the region. Strongly decreasing trends were identified for pasture areas and strongly increasing trends for forest formations and urban infrastructure. Based on analysis of forest formation transitions conducted at 5-year intervals between 1985 and 2020, we observed different patterns of net change between the local, regional, and macroregional levels and the state and biome levels. Our analysis of land-use and land-cover transitions for the most recent years (2018 to 2023), including the period of validity of the EPA Management Plan, indicates that the ecological–economic zoning instrument is effective in containing potential threats; however, it has limitations, since losses of forest formation were observed in all five conservation zones. We emphasize that, although we can attest to the effectiveness of ecological–economic zoning, which in the EPA region has undergone incremental adaptations favorable to the forest transition process, this management instrument is subject to changes in its limits and regulations based on the governance system established at its different levels.

The scope of this theoretical study is centred on the analysis of artistic practices developed during travel, focusing on the construction of the relationship between art and travel from the 16th century to the present. In order to do this, a historical perspective focuses on the journey to Italy, the obligatory destination for travellers in the modern era. From the nineteenth century onwards, contemporary artists sought to observe how travel became an artistic discourse. The term 'artourist' is introduced as a description of the artist who is a traveller and a developer of artistic projects. The research followed the methodology of virtual curatorship, which subjectivises and expands a reflective body of works of art and tourism. This article promotes the argument that tourism, despite the veiled pejorative connotation of academic profiles of the visual arts, can be an essential mechanism for artistic creation and imagination. In defence of free-thinking, this article presents an expanded reflection, pointing to theories and cases that reveal the contributions of the relationship between art and tourism as two complex systems through its protagonist: the travelling artist.

No presente artigo, temos como proposta apresentar o papel das emoções no ativismo de mães e pais de autistas no Brasil durante a década de 1980. A partir da triangulação de fontes documentais distintas (autobiografias, livros acadêmicos do período e matérias publicadas em periódicos), mapeamos as emoções mais comuns expressas pelos familiares em suas narrativas sobre a experiência com seus filhos, com destaque para a infelicidade e o amor. Observamos que as emoções possibilitaram uma análise crítica da realidade, o estabelecimento de vínculos de solidariedade e a construção das primeiras medidas que possibilitaram o reconhecimento dos direitos dos autistas no Brasil.

ABSTRACT: This study aimed to prepare and characterize Nile tilapia (Oreochromis niloticus) waste meal. The experimental design consisted of three treatments (carcass meal, mechanically separated meat meal - MSM, and head meal) and five replications of each treatment. Yield, microbiological quality, pH, water activity, proximate composition, energy value, mineral composition, fatty acid profile, amino acid composition, color, and particle size fractions and the geometric mean particle diameter (GMD) analyses were performed. Data were subjected to ANOVA, and means were compared by Tukey’s test at P < 0.05. Carcass, mechanically separated meat, and head meals had a protein content of 56.45%, 78.60%, and 50.33%, respectively, a lipid content of 7.16%, 13.15%, and 4.58%, respectively, and an ash content of 32.61%, 4.26%, and 38.41%, respectively. The mean yield of fish waste meals was 13%. Oleic, palmitic, and linoleic acids were the major fatty acids in the three fish waste meals, and glutamic acid, leucine, lysine, and glycine were the major amino acids. Color analysis showed that lightness (L*) ranged from 55.32 to 77.19, redness (a*) from 4.44 to 4.88, and yellowness (b*) from 4.13 to 9.51. The GMD ranged from 0.37 to 0.99 mm. The results indicate that Nile tilapia waste meals have high nutritional value and adequate pH, water activity, and microbiological quality for use in human nutrition.

O presente artigo tem como proposta explicitar uma das possibilidades de se fazer Educação fundamentada na responsabilidade de nossa presença enquanto professoras e professores na relação com estudantes, firmando a construção de uma sociedade mais democrática, assegurando liberdades de ser e estar nesse mundo e seus direitos inerentes a espaços equânimes. Dessa forma, o Tocando Corações surge diante do contexto pandêmico, em 2020, como um projeto de envolvimentos no Centro Integrado de Educação Pública (CIEP) Cora Coralina, na cidade de Duque de Caxias/RJ. Um projeto que valoriza os cotidianos, as identidades, empoderamentos e emancipações, baseado em uma Educação como agente transformador de realidades e veículo de fortalecimento de laços solidários, inspirando atos de responsabilidade social. Por meio de vídeos e livros digitais informativos, fazendo circular os materiais criados por estudantes e ex-estudantes nas redes sociais/virtuais, como forma de propagação positiva para o público em geral, um dos objetivos do projeto é de que, mediante conhecimento/arte, existisse um fortalecimento recíproco de combate a COVID-19 e seus desdobramentos tanto sociais, quanto políticos e econômicos, assim como tudo que se referisse a precarização da vida como um todo. São jovens, estudantes, livres e diversos em potencialidades que criam as bonitezas político-poéticas na luta contra o desencantamento da vida, enfatizando, em ações, que através de elos comunitários, é possível transformar de alguma forma a realidade.

ABSTRACT Wild birds have great prominence in the transmission of diseases to humans, mainly due to their ease of access to human populations, raising concerns about the potential impact of that proximity on public health. The present study reports ARV and PBV occurrence in wild birds from an environmental protection area in the Amazon biome, in Pará state, Brazil. We obtained 155 fecal specimens from 47 species of wild birds for RNA extraction, ARV and PBV detection utilizing molecular methods, nucleotide sequencing, and phylogenetic analysis. ARV prevalence was 0.6% (1/155), being positive in an individual of Myrmotherula longipennis, and PBV prevalence was 1.29% (2/155), affecting two individuals of Guira guira. The PBV strains were assigned to genogroup I based on phylogenetic analysis, and they shared a strong phylogenetic link with strains isolated from different geographic locations. The ARV strain was more closely related to strains that had previously circulated in the same region. The presence of ARV and PBV in this habitat suggests that infection cycles of these agents occur naturally in the wild ecosystem, potentially triggering transmission events between bird species and humans. This is the first study on ARV detection in wild birds in Brazil and the first report on the occurrence of PBV in wild Guira guira. Additional studies are required to determine the epidemiology, origin, evolution, and emergence of new potentially pathogenic viruses in the Amazon.

Introduction: Ewing sarcoma (ES) is a highly aggressive type of childhood cancer characterized by a chromosomal translocation resulting in fusions between the gene encoding EWS RNA Binding Protein 1 (EWSR1) and one gene of the ETS family, most frequently FLI-1, resulting in the EWS-FLI1 aberrant transcription factor. ES tumors can contain a subpopulation of cells showing cancer stem cell (CSC) features, which express stemness markers including CD133, OCT4 (Octamer-binding transcription factor 4), and NANOG, and display capacity to form tumorspheres likely enriched in CSCs. Neurotrophin (NT) receptors of the tropomyosin receptor kinase (Trk) family (TrkA, TrkB, and TrkC) may play a role in stimulating ES progression, but their possible role in CSCs remains unknown. Objective: To verify the effect of Trks inhibition on the formation of tumorspheres as well as the gene expression of stem markers. Method: The cells were dissociated and the formation of spheres was induced with supplemented culture medium and the K252a treatment was performed. After RNA extraction, mRNA expression levels of target genes Prom1 (CD133), OCT4 (POU5F1), SOX2, and Musashi-1 (MSI1) were analyzed by qPCR. Results: The pan-Trk inhibitor K252a (100 or 500 mM) hindered tumorsphere formation in human SK-ES-1 ES cell cultures. K252a also reduced mRNA expression of Prom1 (CD133-coding gene) while enhancing expression of OCT4. No changes in mRNA levels of SOX2 or Musashi-1 were observed. Conclusion: These findings provide the first evidence suggesting that Trk activity can influence stemness in ES cells.

Introduction: Short bowel syndrome (SBS) is defined as a severe reduction in intestinal mucosal absorption secondary to reduced intestinal functional area. The main causative factor for SBS is the length of intestinal resection in the neonatal period. The prognosticating factors are age, length of remnant intestine, preserved ileocecal valve, and venous maintenance. Objective: To evaluate the clinical and surgical aspects affecting survival outcomes in neonates with SBS at two tertiary care centers. Patients & methods: Retrospective cohort study involving two university tertiary care neonatal centers with diagnosed SBS. Neonates were allocated into two groups, SBS (

Congenital and chronic liver diseases have a substantial health burden worldwide. The most effective treatment available for these patients is whole organ transplantation; however, due to the severely limited supply of donor livers and the side effects associated with the immunosuppressive regimen required to accept allograft, the mortality rate in patients with end-stage liver disease is annually rising. Stem cell-based therapy aims to provide alternative treatments by either cell transplantation or bioengineered construct transplantation. Human amnion epithelial cells (AEC) are a widely available, ethically neutral source of cells with the plasticity and potential of multipotent stem cells and immunomodulatory properties of perinatal cells. AEC have been proven to be able to achieve functional improvement towards hepatocyte-like cells, capable of rescuing animals with metabolic disorders; however, they showed limited metabolic activities in vitro. Decellularised extracellular matrix (ECM) scaffolds have gained recognition as adjunct biological support. Decellularised scaffolds maintain native ECM components and the 3D architecture instrumental of the organ, necessary to support cells’ maturation and function. We combined ECM-scaffold technology with primary human AEC, which we demonstrated being equipped with essential ECM-adhesion proteins, and evaluated the effects on AEC differentiation into functional hepatocyte-like cells (HLC). This novel approach included the use of a custom 4D bioreactor to provide constant oxygenation and media perfusion to cells in 3D cultures over time. We successfully generated HLC positive for hepatic markers such as ALB, CYP3A4 and CK18. AEC-derived HLC displayed early signs of hepatocyte phenotype, secreted albumin and urea, and expressed Phase-1 and -2 enzymes. The combination of liver-specific ECM and bioreactor provides a system able to aid differentiation into HLC, indicating that the innovative perfusion ECM-scaffold technology may support the functional improvement of multipotent and pluripotent stem cells, with important repercussions in the bioengineering of constructs for transplantation.

O açaí possui grande importância para a economia e dieta da população paraense; no entanto, é frequente a preocupação relacionada à qualidade desse alimento, uma vez que ele está susceptível a diversas contaminações, que vão desde a colheita até seu processamento. Sendo assim, o objetivo do trabalho foi avaliar as condições higiênico-sanitárias dos boxes que processam e comercializam açaí no mercado municipal, Ver-o-Peso em Belém-PA, avaliar a qualidade microbiológica desse produto, e averiguar a conformidade com os padrões estabelecidos pela legislação vigente. Para a avaliação higiênico-sanitária foi elaborado um checklist com 5 blocos de avaliação 31 itens e 100 subitens de verificação. Também foram realizadas análises microbiológicas (bolores e leveduras, Escherichia coli, Salmonella spp. e Staphylococcus aureus) nas amostras coletadas nesses pontos de venda. O resultado do checklist evidenciou que os índices de adequação para os blocos avaliados estão abaixo de 62,5%, sendo classificados no grupo regular e ruim. Quanto às análises microbiológicas, houve presença de Salmonella spp. e E. coli, e os valores para bolores e leveduras e S. aureus se apresentaram acima do que é preconizado pela legislação. Ambas avaliações foram ferramentas complementares e apresentaram baixa adequação às legislações vigentes. Portanto, consumo desse alimento apresenta risco à saúde do consumidor.

Vesicoureteral reflux (VUR) is characterized by retrograde urine flow, caused by impaired occlusion of the intramural portion of the ureter by contraction of the detrusor muscle during urination or secondary to altered bladder dynamics, ureteral obstruction and neuromuscular diseases, such as Phelans syndrome -McDermid. This syndrome is a rare and underreported disease, resulting from the formation of chromosome 22 in a ring and has VUR as its main urological manifestation. The objective of this study is to alert the medical community about one of the differential diagnoses in the VUR etiology, based on the case of a female patient, 4 years and 2 months old, referred to the Pediatric Surgery service of the Mário Covas State Hospital with recurrent infection of urinary tract associated with impaired renal function and bilateral VUR evidenced on cystourethrography. During investigation, the phenotypic findings encouraged the performance of a karyotype that confirmed the alterations found in Phelan-McDermid syndrome. VUR early diagnosis was essential to establish the appropriate therapy, which involved clinical and surgical approaches aimed at improving quality of life, preserving the renal parenchyma and preventing further future complications.

Purpose: Breast cancer is the most common female malignancy and melanoma is the most lethal type of skin cancer. Traditional therapy for cancer treatment is far from satisfactory due to drug resistance and side effects, thus a search for new medicines is being emphasized. Palladium(II) complexes have been reported as anticancer potential agents. In this work, the anticancer activities and cell death induction of a new series of square-planar Pd(II) complexes were evaluated against MCF-7 and MDA-MB-435 cancer cells. Methods: MCF-7 (breast carcinoma) and MDA-MB-435 (melanoma) cells were cultivated, and treated with ligand and Pd(II) complexes. Cell growth, migration and adhesion inhibition, morphological alterations, cell death induction and, DNA interaction upon treatment were studied. Results: Pd(II) complexes exhibited both short and long-term antiproliferative effects on both cell lines, reducing by 80% cell growth in the SRB assay and abolishing longterm proliferation, estimated by the clonogenic assay. Complexes reduced significantly (P

Acidovorax citrulli is the causative agent for bacterial fruit blotch in melons and watermelons. This disease causes several problems in the production and consumption of watermelon. The knowledge of the chemical profile of the interaction between the bacteria and the fruit can help in the adoption of measures to control this disease. Thus, this study investigated the volatile organic compounds (VOCs) in the fruit and seed of infected and healthy watermelon. In the present study, we used headspace-solid phase microextraction (HS-SPME) and gas chromatography–mass spectrometry (GC–MS). Chemometric analysis, Hierarchical cluster analysis (HCA) and Principal component analysis (PCA), was used and the results show that this technique associate to GC–MS can be used to differentiate healthy from infected samples. Phenylethyl alcohol was produced by bacteria cultivated in vitro as well as in infected fruits and healthy and infected seeds. Therefore, detection of some phenolic compounds (phenol, benzyl alcohol, p-cresol and 2-mehoxy-phenol), acetoin and 2,3-butanediol was observed in the infected samples, which indicated the presence of a possible defense mechanism against infection.

ABSTRACT The work was intended to evaluate the effect of different organic compounds originating from the mixture of agroindustrial and urban wastes, as well as their doses in the physiology and production of cowpea. The experiment was conducted under a randomized block design, in a 4 x 5 + 2 factorial arrangement, with four organic fertilizers (3 composed obtained from of sewage sludge, green coconut shell, carnauba butt; and sewage sludge biochar), five doses (20, 40, 60, 80 and 100 t ha-1) and two additional treatments (without fertilization and mineral fertilization). We evaluated the leaf gas exchange in three phenological stages and the productive aspects. Regarding the physiological variables, the compounds with carnauba butt and green coconut shell promoted the best results and throughout the crop cycle, the gas exchange decreased. The productive aspects were increased by about 60%, especially due to the treatments with organic compounds. The PCA can confirm the univariate results, with emphasis on compounds with green coconut shell and carnauba butt. The high percentage of explanation found in axis 1 (60.49%) may be associated with the fact that the gas exchange and production variables are highly responsive to fertilization. The treatment with biochar caused a reduction in both in the physiological and in the productive aspects. The compounds with carnauba tip and green coconut shell promote satisfactory results, being viable alternatives to complement chemical fertilization with an indicated dose of 300g pot-1 or 60 t ha-1.

Este estudo teve por objetivo averiguar e compreender como a temática saúde está proposta nos documentos oficiais de ensino do Brasil, Chile e Colômbia. É parte de uma pesquisa mais ampla que investiga currículo de Ciências da Natureza em países da América Latina. Trata-se de um estudo qualitativo do tipo documental em que priorizou –se a busca em documentos curriculares normativos dos três países que discorrem sobre a temática saúde no ambiente escolar. Os documentos foram respectivamente Base Nacional Curricular Comum (Ministério da Educação, 2018), Bases Curriculares 1º ao 6º básico, Bases Curriculares 7° básico a 2° médio (Ministerio de Educación, 2015a, 2015b) e Estándares Básicos de Competências (Ministério da Educación Nacional, 2006). Nos documentos analisou- se as capacidades que os estudantes devem desenvolver ao longo do processo de escolarização. A fase de escolaridade escolhida para análise em cada documento está entre as idades de 11 a 14 anos. Pode-se averiguar que o tema saúde trabalhado nos países apresenta similaridades entre si, porém, foram encontradas algumas divergências entre eles em relação ao ano de escolaridade que são abordados os temas de alimentação saudável e prática de atividade física. As similaridades encontradas na temática saúde estão relacionadas aos conteúdos abordados, sendo elas substâncias psicoativas, sexualidade, imunização e Infecções Sexualmente Transmissíveis, entretanto, os conteúdos diferem quando ministrados nos anos de escolaridade dos países. Conclui-se que a temática saúde está em consonância entre si quanto à fase de escolaridade escolhida nos três países, portanto, embora possa haver diferenças culturais enquanto diferentes nações, há convergência entre os objetivos para os anos escolares analisados em relação à Educação em Saúde.

Introduction: The interplay of water and light, regarded as the main driver of tropical plant dynamics, determines leaf phenology and ecosystem productivity. Leaf phenology has been discussed as a key variable to explain photosynthetic seasonality in evergreen tropical forests, but the question is still open for seasonally tropical ecosystems. In the search for implementing long-term phenology monitoring in the tropics, phenocameras have proven to be an accurate method to estimate vegetative phenology in tropical communities. Here, we investigated the temporal patterns of leaf phenology and their relation to gross primary productivity (GPP) in a comparative study across three contrasting tropical biomes: dry forest (caatinga), woodland savanna (cerrado), and rainforest (Atlantic Forest).Methods: We monitored leaf phenology (phenocameras) and estimated gross primary productivity (eddy-covariance) continuously over time at three study sites. We investigated the main drivers controlling leaf phenology and tested the performance of abiotic (climate) and biotic (phenology) factors to explain gross primary productivity across sites.Results: We found that camera-derived indices presented the best relationships with gross primary productivity across all sites. Gross primary productivity seasonality was controlled by a gradient of water vs. light, where caatinga dry forest was water-limited, cerrado vegetation responded to water seasonality and light, and rainforest was mainly controlled by light availability. Vegetation phenology was tightly associated with productivity in the driest ecosystem (caatinga), where productivity was limited to the wet season, and the camera-derived index (Gcc) was the best proxy for gross primary productivity.Discussion: Leaf phenology increased their relative importance over gross primary productivity seasonality at less seasonal sites (cerrado and rainforest), where multiple leafing strategies influenced carbon exchanges. Our multi-site comparison, along with fine-scale temporal observations of leaf phenology and gross primary productivity patterns, uncovered the relationship between leafing and productivity across tropical ecosystems under distinct water constraints.

Introduction: Charles Bonnet syndrome (CBS) is a condition related to patients having complex visual hallucinations and visual loss due to ophthalmologic disease, without cognitive impairment. CBS is an important differential diagnosis of dementia syndromes, and the correct diagnosis has a great impact on the quality of life of those who suffer from the stigma of psychiatric disease. Objective: The objective of the present study is to determine the impact and review symptoms of CBS in patients with visual loss due to age-related macular degeneration (AMD) by using a questionnaire. Method: Sixty patients suffering from AMD were forwarded from the Retina Sector of the Ophthalmology Service of the Hospital do Servidor Público Estadual de São Paulo to the Low Vision Sector for a cognitive assessment questionnaire. Results: Of the 60 patients studied, 10 were diagnosed with CBS, thus representing 16.6% of the incidence of CBS cases in individuals with AMD. Among these 10 cases, males represented 30% versus females who represented 70% of the total. Patients over 80 years old represented 50% of those who were diagnosed with CBS. CBS represents an important co-diagnosis in AMD patients. Conclusion: The research highlights the utility of the cognitive assessment questionnaire as a valuable tool for easily diagnosing the syndrome in patients with AMD. This tool facilitates the identification of the condition, enabling the recommendation of appropriate clinical treatments and the provision of essential psychosocial support.

Obesity is a chronic, multifactorial and complex metabolic disorder, in which organic damage can be evident in the short or long term, especially dermatological disorders. With the objective of verifying the association between the body mass index and the presence of dermatological conditions, students at a public school in the backcountry of Bahia were studied. This was a cross-sectional study in which 169 schoolchildren were evaluated. The outcome was skin conditions, and the independent variables were BMI, age, and sex. Data were analyzed with the chi-squared test and an α≤0.05. About 41 students (24.3%) were underweight, 92 (54.4%) were eutrophic, and 36 (21.3%) were obese. Among the dermatological conditions, stretch marks stood out with a prevalence of 58%, followed by cellulite with 26%, and acne with 24.3%. The age group (14-20 years) was significantly associated with BMI values (p=0.05). Similarly, acanthosis (p=0.05), striae, hidradenitis, and cellulite also showed a significant relationship with BMI (p=0.01). There was statistical significance (p=0.01) when the presence of up to six dermatoses was compared with the low weight, eutrophic, and obese groups. Certain skin conditions were significantly associated with BMI. It is necessary to carry out educational awareness and prevention actions aimed at these young people that lead to a reduction in obesity cases, considering that in this group the dermatological changes were more evident.

Objetivo: compreender como propostas de educação em saúde podem contribuir para o conhecimento e atitudes dos adolescentes frente a depressão. Método: trata-se do recorte de um trabalho de conclusão de curso de graduação em enfermagem da Universidade Federal de Campina Grande, realizado no ano de 2018, fundamentado no método da pesquisa-ação e analisado por meio do Discurso do Sujeito Coletivo. Resultados: após realização do diagnóstico situacional foi possível realizar o planejamento e execução de três encontros para realização de ações educativas com uso de dinâmicas e metodologias que proporcionaram a participação dos jovens, bem como o diálogo do grupo e a construção de conhecimentos relacionados a depressão. Considerações finais: os atos educativos apresentaram-se positivos como oportunidade para a autonomia de adolescentes acerca da depressão, mostrando o quão significativo pode ser o uso deste tipo de metodologia para a transformação de realidade e resolubilidade de problemas sociais.

The biological roles of deubiquitinating enzymes (DUBs) in pancreatic ductal adenocarcinoma (PDAC) are not fully explored. Here the authors perform activity based proteomics with a loss of function genetic screen and identify that USP25 promotes PDAC growth and survival through HIF-1 protein stability and transcriptional activity.

Objetivo: caracterizar os encaminhamentos e a resolutividade da consultoria em aleitamento materno em uma unidade de alojamento conjunto. Método: estudo transversal descritivo realizado com 231 puérperas e seus recém-nascidos internados em alojamento conjunto no sul do Brasil. A coleta de dados foi realizada no período de agosto de 2016 a maio de 2017. Os dados foram analisados mediante estatística descritiva. Resultados: os motivos prevalentes para o encaminhamento foram dificuldade na técnica de amamentação (81,7%), primiparidade (57,8%), anatomia mamária (28,7%), presença de fissuras mamilares (19,6%) e dor ao amamentar (18,3%). A satisfação com o atendimento foi relatada por 97,8% das puérperas. Quanto a resolutividade, 70,6% considerou o atendimento totalmente resolutivo, 26,4% parcialmente e 3,0% não resolutivo. Conclusão: a consultoria em aleitamento materno foi resolutiva na maioria dos encaminhamentos, motivados por dificuldades que poderiam predispor uma interrupção precoce da amamentação, demonstrando a eficácia da inserção desse profissional nos serviços de saúde.

Introduction:The increase in availability and nutritional composition of oilseed co-products has made it essential to study the use of this biomass.Methods:The objective of this work was to investigate the effects of including oilseed cakes on intake and digestibility, performance, carcass characteristics and meat sensory in feedlot lambs. Twenty-four crossbred Dorper × Santa Inês lambs, with initial body weight of 30 ± 1.3 kg, male, castrated, aged 4–5 months, were distributed in a completely randomized experimental design with four treatments (diets) and six replications (animals), confined in individual stalls for 70 days.Results:The inclusion of tucuma cake (Tuc) reduced dry matter intake (p 0.05). Meat from lambs on the control diet was rated as less fibrous and more tender (p

In explaining and forecasting real life scenarios, statistical distributions are very helpful. It is very important to select the best fitting statistical distribution for modelling data. In analysis of real world phenomena like in reliability and economics, we may find distributions for bounded data observed as percentages, proportions or fractions (see, for example, Marshall and Olkin (2007)). In this context, in view of pertinent transformation on the Gumbel Type-II model, we suggest and study the unit Gumbel Type-II (UG-TII) model and explore few of its statistical characteristics. We also consider various methods of estimating the unknown parameters of UG-TII model from the frequentist perspective. Monte Carlo simulations are worked out in order to compare efficiency of suggested estimation methods for small as well as large samples. The efficiency of estimators is measured using simulated samples in terms of their bias and mean square error. In the end, two datasets have been examined in attempt to validate the realistic possibilities of new model. In comparison to the six severe competitors.

Introdução: Algumas pesquisas apontam para uma maior prevalência de Compulsão Alimentar Periódica (CAP) e Transtorno da Compulsão Alimentar Periódica (TCAP) em jovens universitários devido a mudanças no estilo de vida, pressão psicológica e diminuição no tempo disponível para a alimentação. Objetivo: Investigar a presença de compulsão alimentar periódica em universitários dos cursos de Nutrição e Fisioterapia. Materiais e Métodos: Trata-se de uma pesquisa descritiva, quantitativa e transversal. A população foi composta por 252 acadêmicos dos cursos de Nutrição e Fisioterapia. Foi utilizado a escala de compulsão alimentar periódica (ECAP) um questionário autoaplicável para avaliar a presença ou não de TCAP. Resultados: A maior parte dos acadêmicos não apresentou compulsão tendo uma porcentagem de 73,4%, em vista que 20,6% apresentaram uma certa variação ao ato de comer e 6% apresentaram a compulsão alimentar periódica. Os valores que contribuíram para a diferença significativa foram 82,5% acadêmicos do curso de Nutrição, que se apresentaram normais sem obter a compulsão, para 26,1% do curso de Fisioterapia que tem uma variação de inclinação ao comer muito. Conclusão: Houve diferenças significativas relacionadas ao hábito de comer quando se encontra chateado, como também em saber as calorias ideais a serem ingeridas por dia, além de uma diferença na prática de atividade física e na escala da compulsão alimentar.

A plataforma digital YouTube tem se tornado popular entre as crianças e uma prática cuja popularidade vem aumentando nesse espaço é a do unboxing, que consiste em vídeos nos quais seus protagonistas, denominados YouTubers, abrem embalagens e fazem demonstração de novos produtos, como brinquedos e itens colecionáveis. O presente artigo buscou analisar, à luz do Direito do Consumidor, se a eventual publicidade veiculada por meio desses vídeos gera responsabilidade civil por publicidade ilícita do YouTuber anunciante. Para tanto, foi realizada pesquisa exploratória de natureza bibliográfica, em doutrina especializada, e documental, a partir das decisões do Conselho Nacional de Autorregulamentação Publicitária. Foi empregado o método indutivo, uma vez que se partiu de uma análise de fatos específicos a respeito da atuação dos YouTubers para uma conclusão geral referente ao tema da responsabilidade civil por publicidade ilícita. Verificou-se a presença de elementos da publicidade ilícita nos vídeos unboxing, não só pela abusividade do direcionamento ao público infantil, mas também pelo caráter velado da publicidade. Ademais, concluiu-se pela responsabilidade civil objetiva dos YouTubers que veiculam tais conteúdos, visto que participam ativamente da elaboração da comunicação mercadológica e podem receber contraprestação da empresa fornecedora, além de exercerem grande influência sobre seus seguidores.

ABSTRACT Purpose: to identify the frequency and levels of kinesiophobia and catastrophizing in patients with temporomandibular disorders who had been submitted to speech-language-hearing therapy. Methods: the sample comprised patients with myogenous (predominantly) and mixed temporomandibular disorders in the study group and healthy individuals in the control group. The instruments used were the Diagnostic Criteria for Temporomandibular Disorders, Tampa Scale for Kinesiophobia, and Pain Catastrophizing Scale. Statistical analyses were performed with the Mann-Whitney test (to compare the means on each scale between the groups) and the Spearman’s correlation coefficient test (to analyze the correlation between the scales in each group and its significance). Results: the study group had a higher pain catastrophizing index than the control group. Likewise, the study group had greater kinesiophobia positive indices, whereas the control group had lower ones. A moderate positive correlation was also identified between kinesiophobia and catastrophizing in the study group. Conclusion: patients presented with temporomandibular disorders have higher levels of kinesiophobia and catastrophizing than subjects not diagnosed with the disorder.

OBJECTIVE: To understand the academic training of geriatrics residents and their supervisors regarding the sexuality of older adults, as well as practical approaches to the subject in their work routines. METHODS: This qualitative study was conducted with geriatrics residents and their supervisors at a public hospital in Recife, PE, Brazil in 2019 and 2020. RESULTS: A partial understanding of the respondents' concept of sexuality was identified through statements that expressed confusion between sexual intercourse and sexuality, as well as a lack of knowledge about sexuality on an individual level. Although the respondents affirmed the importance of discussing the subject, they reported that they do not, except passively. The respondents discuss this issue depending on the patient's questions, despite acknowledging their difficulty in seeking a health service to talk about sexuality-related issues. Finally, the lack of an approach to sexuality in geriatric consultations was linked with gaps in undergraduate and specialization programs about general care for older adults, resulting in a feeling of unpreparedness to face the taboos and prejudices associated with sexuality. CONCLUSION: Although professionals consider it important to address sexuality with patients, most of them do not do so in medical consultations due to a number of difficulties, including the lack of a protocol to follow, which leads to a passive approach. Therefore, professionals acknowledge the difficulty of addressing the subject and associate it with deficiencies in their academic training.

Abstract Guabiju tree (Myrcianthes pungens) belongs to the Myrtaceae family, with wide occurrence in Rio Grande do Sul (RS), southern Brazil, demonstrates great commercial potential regarding the consumption of its fresh fruit, which has a sweet taste and can be used in drinks, jellies and ice creams, in addition to its nutraceutical properties. As their main characteristic, rusts present the formation of orange pustules containing urediniospores of the pathogen on affected organs. The action of the pathogen causes deformation of stems, leaves, flowers and fruits, thus interfer-ing with the physiological processes of the plant. Thus, the present work aimed at presenting information on the occurrence and confirmation of the causal agent of guabiju rust, in addition to reporting the accessions most susceptible and resistant to Austropuccinia in the guabiju working collection of Eldorado do Sul, RS, Brazil. The diagnosis of the disease was based on symptoms, observation of fungal structures by light microscopy and molecular analyses. From microscopy, ellipsoid to ovoid and slightly equinulate urediniospores were observed, characteristic of Austropuccinia sp. The sequence of the internal transcribed spacer (ITS) region of the isolate showed 99.06% similarity with sequences from the same region of A. psidii deposited on the nucleotide database - GenBank (NCBI). This is the first report of rust associated with guabiju in the state of Rio Grande do Sul, Brazil. From the diagrammatic scale developed, it was possible to identify different levels of susceptibility to A. psidii in guabiju accessions under study.

ABSTRACT Purpose: to describe the strategies used to minimize the nocebo effect in health communication. Methods: an integrative review of the literature. The keywords “nocebo effect” and “health communication” and their combinations were used in English, Portuguese, and Spanish to search publications from 2011 to 2021 in MEDLINE, Latin American and Caribbean Health Sciences Literature (LILACS), Cochrane Library, EMBASE, and Web of Science/ISI. The following research question was used: “Which strategies have been used to minimize the nocebo effect in health communication?”. Literature Review: altogether, 77 articles were found, although only six met the inclusion criteria and comprised the review sample. Their year of publication ranged from 2015 to 2021. Positive framing, assertive communication, and contextual factors were the strategies used to minimize the nocebo effect. Conclusion: the strategies used to minimize the nocebo effect were contextual factors, motivational talk, positive framing, assertive communication, and empathetic communication. These communication techniques are seemingly effective, though still little known by health professionals. This knowledge is important as it helps develop communicative skills aiming at humanized patient care.

The COVID-19 pandemic and its effects on public health have urgently demanded effective health policies to avoid the spread of COVID-19. Thus, public administrators have implemented non-pharmacological and pharmacological interventions to mitigate the pandemic's impacts and strengthen health services. The aim of this ecological study is to describe the scenario of COVID-19 pandemic in a Brazilian city, during 2 years. This ecological study was carried out in Nova Friburgo, a Brazilian city, for 105 weeks (two years), from March 29, 2020 (week 1) to April 02, 2022 (week 105). Data on COVID-19 cases and COVID-19 deaths, occupation of COVID-19 exclusive beds in hospitals, community mobility, vaccination, government regulation on the opening of city establishments and city risk assessment were collected from public datasets. Four waves of COVID-19 cases and deaths were observed during this period. The first case occurred in week 1 and first death in week 3 of this study. The highest peaks of cases and deaths were observed during the third wave with 1,131 cases (week 54) and 47 deaths (week 55) and where the highest occupation of COVID-19 exclusive beds in local hospitals occurred. Interventions from more restrictive to more flexible, were implemented throughout this study, including lockdown and gradual return in economic and social strata levels. Vaccination began on week 43 and at the end of this study 89.91% of the total population was vaccinated with at least one dose, being 83.22% fully vaccinated. A deep description of several interventions used to avoid COVID-19 spread in a Brazilian city during 2 years of this pandemic can help promote better decision-making in the future while it exposes the challenges of conducting public health policies in a pandemic scenario.

Dermatofibrosarcoma protuberans (DFSP) is an extremely rare and potentially aggressive soft tissue tumor. Around 85 to 90% of DFSP cases are low-grade tumors, while the fibrosarcomatous variant (DFSP-FS) is associated with medium and high-grade neoplasms. DFSP affects more young adults, in their 30s; however, it can be present in all ages. It has a high potential for locoregional dissemination and recurrence, directly related to tumor size. In the present study, a case of dermatofibrosarcoma protuberans with local recurrence after surgical treatment will be reported, subsequently treated with imatinib and a new surgical approach, with no new recurrences so far. The effectiveness of imatinib is noted in a deep, infiltrative and relapsed DFSP, in which upfront surgery would cause significant functional and cosmetic damage. Imatinib allowed an important clinical improvement for the patient, with tumor reduction in the initial weeks of treatment.

O presente estudo objetivou investigar a relação entre a idade (sub-13 e sub-15) e o momento competitivo (início e final da competição) com os níveis de coesão de grupo em atletas amadores de basquetebol. Participaram 26 atletas (12 e 14 respectivamente). O instrumento utilizado foi o Questionário de Ambiente de Grupo: GEQ. As análises foram conduzidas entre os grupos, comparando os resultados do início e do final do campeonato. Utilizou-se o teste U de Mann-Whitney para comparação entre grupos, e o Friedman para análise intragrupo. Os resultados demonstraram que não houve diferença significante entre os grupos em nenhum momento do campeonato (início e final), para nenhuma dimensão, com os grupos investigados apresentando elevados escores nas dimensões relacionadas à tarefa, tanto no início quanto no final do campeonato. Assim, pode-se considerar que nem a idade, nem o momento da competição influenciaram os níveis de coesão, pois os dois grupos do estudo apresentaram níveis de coesão similares e elevados, tanto no início quanto no final da competição, o que é apontado como relevante para o bom desempenho esportivo dos atletas. Palavras-chave: Coesão de grupo; basquetebol; psicologia do esporte; ambiente de grupo.

IntroductionSome studies have shown poor agreement between intraoperative and histopathological classifications for appendicitis, despite their routine use in clinical practice.ObjectiveTo investigate the agreement between histopathological and intraoperative classifications for pediatric appendicitis and evaluate the predictive potential of these classifications for the post-operative outcome.MethodsA retrospective, longitudinal, observational single-center study, carried out with 485 patients up to15 years of age, with a confirmed diagnosis of acute appendicitis by histopathological evaluation. The histopathological results classified the appendices as uncomplicated appendicitis when there was confirmation of the diagnosis of appendicitis without necrosis or perforation and complicated appendicitis when there was extensive necrotic tissue in the outer layer of the appendix or signs of perforation. The intraoperative findings were classified as uncomplicated appendicitis when the appendix presented with hyperemia and edema or fibrinous exudate and complicated appendicitis when the appendix showed necrosis, abscess, or perforation. The kappa index determined the agreement and the prediction relationships using a generalized linear model.Results43.9% of cases were classified as complicated appendicitis by histopathological evaluation and 49.7% by intraoperative classification. The agreement analysis between the histopathological and intraoperative classification showed a moderate agreement, with a Kappa index of 0.419 (0.337–0.501). There was an association (P < 0.05) between the intraoperative classification and the post-operative clinical outcomes (time to start feeding, fever, intraabdominal collection, length of stay, the need for antibiotic therapy changing, and need for ICU). There was no association between histopathological classification and post-operative outcomes.ConclusionThe agreement between the two classifications was moderate, and the intraoperative classification was able to predict the post-operative clinical outcomes.

Sepsis is a generalized disease characterized by an extreme response to a severe infection. Moreover, challenges remain in the diagnosis, treatment and management of septic patients. In this mini-review we demonstrate developments on cellular pathogenesis and the role of Caveolin-1 (Cav-1) in sepsis. Studies have shown that Cav-1 has a significant role in sepsis through the regulation of membrane traffic and intracellular signaling pathways. In addition, activation of apoptosis/autophagy is considered relevant for the progression and development of sepsis. However, how Cav-1 is involved in sepsis remains unclear, and the precise mechanisms need to be further investigated. Finally, the role of Cav-1 in altering cell permeability during inflammation, in sepsis caused by microorganisms, apoptosis/autophagy activation and new therapies under study are discussed in this mini-review.

Objetivo: identificar e descrever os procedimentos invasivos/dolorosos e as medidas analgésicas aplicadas em um recém-nascido prematuro extremo durante o período de internação em uma Unidade de Terapia Intensiva Neonatal. Método: trata-se de uma pesquisa observacional, tipo estudo de caso de caráter intrínseco, quantitativo, descritivo e analítico. Os dados foram coletados do prontuário de um lactente que nasceu com idade gestacional de 26 semanas e com seguimento no Ambulatório Canguru, de um hospital escola, do interior do Estado do Paraná. Resultados: o recém-nascido foi submetido a 368 procedimentos invasivos e dolorosos durante todo o período de internação (73 dias), sendo a aspiração de vias aéreas o procedimento prevalente realizado 217 vezes. Destes procedimentos, 64% foram realizados com o uso de analgesia e 36% sem medidas analgésicas. Considerações Finais: os procedimentos dolorosos aos quais o RN foi submetido, durante o período de internação foram expressivos. Por meio de uma ação efetiva e segura foi prescrito o método farmacológico para minimizar a dor.

Objetivo: analisar a associação do sobrepeso com variáveis sociodemográficas, condições de saúde e indicadores do estilo de vida de colaboradores técnicos de uma instituição de ensino superior privada. Materiais e Métodos: Estudo transversal analítico, realizado em uma instituição particular do norte de Minas Gerais. Adotou-se uma amostra probabilística aleatória, constituída por 101 colaboradores técnicos. A coleta de dados foi realizada atraves da avaliação antropométrica e por meio de questionários (sóciodemográficas, condições de saúde e estilo de vida fantástico). Para análise estatística foi estimada a frequência absoluta e relativa. A associação entre as variáveis foi analisada pelo teste do qui-quadrado e as variáveis associadas até o nível de 20% foram analisadas em conjunto por meio de Regressão Logística, sendo assumidas no modelo final apenas as variáveis associadas até o nível de 5%. Resultados: A prevalência sobrepeso/obesidade foi de 64,4%. Entre os colaboradores técnicos o sobrepeso/obesidade foi associado ao estado civil (OR=1,30 p=

Objetivo: Desvelar o que vem sendo produzido pela enfermagem sobre as experiências enfrentadas pelos familiares de crianças hospitalizadas. Metodologia: revisão integrativa a partir da busca nas bases PubMed, LILACS e na biblioteca Virtual SciELO, utilizando os descritores: hospitalized child, family, nursing, durante o mês de janeiro de 2018. Selecionaram-se estudos publicados entre 2011 e 2017, nos idiomas inglês, português e espanhol. Após a análise dos dados, foram selecionados 31 estudos; Resultados: elaborou-se as categorias: adaptação da rotina familiar; afastamento do restante da família e dos filhos sadios; desajuste diante da estrutura física e falta de conforto hospitalar; procedimentos médicos, enfermagem e normas/rotinas rígidas. Conclusão: a hospitalização de uma criança interfere significativamente na vida dos familiares, afetando seu relacionamento familiar, sua saúde física e mental e a manutenção de sua rede social.

Objetivo: Desvelar a produção acerca da assistência de enfermagem prestada às crianças/adolescentes vítimas de violência. Métodos: Trata-se de uma revisão sistematizada realizada com consulta nas bases de dados: LILACS, Scielo e BDENF. Foram selecionados 19 artigos para compor este trabalho. A análise de dados deu-se por meio da proposta de Mendes, Silveira e Galvão. Resultados: Os dados foram discutidos através dos tópicos: despreparo dos profissionais frente aos casos de violência infantil; sentimentos dos profissionais envolvidos no cuidado à criança/adolescente vítima de violência; notificação, protocolos e rotinas na assistência à criança/adolescente vítima de violência; estratégias de assistência à criança/adolescente vítima de violência. Conclusão: Os profissionais de enfermagem não se sentem preparados para atuarem frente aos casos de violência infantil. Identificou-se a necessidade de protocolos assistenciais que respaldem a assistência profissional. Ademais, é importante o fortalecimento da rede de atenção intersetorial que garanta a assistência adequada às vítimas e suas famílias.

This article investigates the relationship between anaphoric processing and reading from a Psycholinguistic perspective, aiming to know and analyze Brazilian studies that relate these two axes and to propose deliberations for pedagogical implications to the teaching of reading. Thus, this article is characterized as a bibliographic research, carried out through the systematic review method and the study of the literature on reading processing, comprehension and teaching. The pieces of research analyzed through the systematic review are all experimental and their results show the processing cost differences generated by different anaphoric constructions. Regarding pedagogical implications, the deliberations are based on 1) reading has to be taught; 2) the text is the stimuli readers access to comprehend; 3) text nature and composition have direct implications in processing as well as in its result; 4) the written text is constituted by a web from which co-reference is an important part; 5) anaphor resolution is, therefore, central to text comprehension and it has to be explicitly and systematically taught, which means the point in the classroom environment is not the text analysis itself, but its analysis concerning the reader in a reading activity aiming at comprehension.

Este artigo investiga a relação entre processamento anafórico e leitura em perspectiva psicolinguística, visando conhecer e analisar estudos brasileiros que relacionam esses dois eixos e propor ponderações sobre implicações pedagógicas ao ensino da leitura. Trata-se, pois, de pesquisa bibliográfica, desenvolvida pelo método de revisão sistemática e pelo estudo da literatura acerca do processamento e da compreensão em leitura e do seu ensino. As pesquisas analisadas no estudo de revisão são experimentais e seus resultados demonstram diferenças de custos de processamento geradas por distintas construções anafóricas. Quanto às implicações pedagógicas, as ponderações respaldam-se nos seguintes princípios: i) leitura se ensina; ii) o estímulo a que o/a leitor/a acessa visando à compreensão é o texto escrito; iii) a natureza e a constituição do texto têm implicações diretas tanto no processamento quanto no seu resultado; iv) o texto escrito se constitui por meio de uma trama da qual a correferenciação é parte importante; v) a resolução de anáforas, portanto, é fundamental à compreensão dos textos e deve ser explícita e sistematicamente ensinada, não se tratando, assim, de análise do texto pelo texto em sala de aula, mas de sua análise na relação com o/ a leitor/a em atividade de leitura objetivando a compreensão.