The thalamus is a large and well-differentiated nuclear mass and many of its connections have been worked out anatomically. Primarily, it has been considered to be the end station of most of the sensory systems of the body, being the rccipient of at least seven afferent tracts. Despite this, in cases of tmnors originating in the thalamus, sensory signs and symptoms are not at all prominent. 6 Furthermore, in the operation of chemoor electrothalamectomy, lesions are placed deliberately in the ventrolateral thalamus, and sensory sequelae arc not common. :~ The thalalnus, with special reference to the thalamic reticular system, has been considered to play a role in the coordination of cortical electrical activity and in the maintenance of consciousness. 5 Yet, recent studies of hemispherectomy and hemithalamectomy in the monkey have shown no such disturbance of consciousness, u The most striking result of lesions of the thalamus to date has been the relief of abnormal motor phenomena such as parkinsonism and hemiballismus, results that are hard to understand in the light of present knowledge and physiology? Following a helnidecortication in both monkey and man, there usually is a temporary abolition of all forms of sensation. TM This then is followed by a partial return of sensations of light touch and pinprick over the face and body, but sense of position and other forms of deep sensibility are abolished permanently. Two explanations have been offered to explain the results of hemidecortication: either the thalamus of the ablated side is sufficient to account for the residual sensation or there is ipsilateral representation in the opposite thalamus. Convincing evidence has been advanced to support both points of view. 4 I t is, of course, not possible to perform a hemidecortication without performing a partial thalamectomy as all cortical relay and association nuclei of the thalamus will show retrograde degeneration. 9 The preservation of motor function following hemicorticectomy generally has been attributed to ipsilateral cortical representation rather than to the residual basal ganglia. ~ The results of ablation of the thalamus in primates have not been studied satisfactorily until recently. Although studies of hemidecorticare animals had been made by many observers, it was Mettler 7 who, in 1943, succeeded in removing hemisphere, thalamus and subthalamus in a monkey in two operations. However, it remained for White et al. 11 to develop a single-staged surgical technique that resulted in the survival of most of the animals. They did not attempt to isolate tile afferent arteries first but carried out a sectional removal, entering the 3rd ventricle widely. They noted tile following: State of consciousness--within s 6 hours after the operation, the animal was awake and responding to the environment. I t was never somnolent. The animal would begin to eat ~4-48 hours after the operation and resumed normal hehavioral patterns within ~ weeks. Motor activity there was an initial flaccid hemiplegia, hut the animal was crawling within clays, sitting by 4 days, and walking at 1 week. Timre was excellent motor recovery in ~-3 months, the animal being able to stand, walk, run and climb. I t did not regain fine movements in foot or hand. There was a limited spasticity and a slight hyperreflexia of the involved side without a Babinski's sign. No extrapyramidal symptoms were present. Sensation--there was complete hemianalgesla up to ~ hours. Following this there was gradual improvement, reaching a maximum in 1 month. Response to pin-prick was maximum in the face. Localization was poor and usually limited to recognition of the extremity stimulated. Response to heat was fairly good, apparently being interpreted as painful. There was no response to touch or vibration and tests for sense of position, hopping and placing were absent. Control hemidecorticate animals recovered sensation more rapidly and to a higher degree than (lid hemispherectomized animals. Comparable preparations in man are lacking. As pointed out by Penfield and Evans, S the operation designated as hemispherectomy should in reality be called a hemicorticectomy because every effort is made to spare the thalamus and basal ganglia. Austin and Grant 1 found after "hemispherectomy" complete degeneration of the nucleus ventralis posterolateralis in the presence of pin-prick response, and postulated an ipsilateral thalamic representation.